Full ingredients list Dettol Even Tone Hygiene Soap

EWG	CIR	Ingredient name & cosmetic function	Notes
1	A	Sodium Palmate (Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Surfactant, Sufactant)
1	A	Sodium Palm Kernelate (Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Sufactant)
1		Water (Solvent)
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
5 8	A	Talc (Skin Protecting, Opacifying, Abrasive, Absorbent, Bulking Agent, Anticaking Agent, Slip Modifier)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin
1 2	B	Sodium C14 16 Olefin Sulfonate (Surfactant, Cleansing, Foaming)	Sulfate
1		Sodium Chloride (Masking, Viscosity Controlling, Bulking Agent)
1 3		Titanium Dioxide (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying)	UV Protection Good for sensitive skin
1		Calcium Oxide (pH adjusting agent, pH adjusting agent)
1		Prunus Armeniaca (Apricot) Seed Powder (Abrasive)
3		Peg 7 Amodimethicone (Skin Conditioning, Emollient, Humectant, Hair Conditioning)
1		Cymbopogon Flexuosus Oil (Masking, Fragrance)
1	B	Trideceth 10 (Emulsifying, Surfactant)
3 5		Citral (Masking, Fragrance, Flavoring Agent)	Allergen
1 2		Etidronic Acid (Chelating Agent)
2	A	Tetrasodium Edta (Chelating Agent)
1	B	Sodium Sulfate (Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent)
1	A	Hydroxypropyl Cyclodextrin (Skin Conditioning, Masking, Emulsion Stabilising, Chelating Agent)
1	A	Acetic Acid (Masking, Fragrance, pH adjusting agent, pH adjusting agent)
1	B	Tetrabutyl Ammonium Bromide (Surfactant, Emulsifying, Antistatic Agent, Antimicrobial, Cosmetic Biocide, Preservative)
5	B	Methylchloroisothiazolinone (Preservative)
7	B	Methylisothiazolinone (Preservative)

Sodium Palmate

Other name: Saponified Palm Oil

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Surfactant, Sufactant

1. Definition Sodium Palmate:

Sodium Palmate is a sodium salt derived from palm oil and is commonly used in the production of soap and cosmetics. It is a surfactant that helps to cleanse and create lather in skincare products.

2. Use:

Sodium Palmate is often used as a cleansing agent in soap bars, body washes, and facial cleansers. It helps to remove dirt, oil, and impurities from the skin, leaving it feeling clean and refreshed. Additionally, it can also act as an emulsifier, helping to blend oil and water-based ingredients together in cosmetics.

3. Usage Sodium Palmate:

When using products containing Sodium Palmate, it is important to follow the instructions provided on the packaging. Avoid getting the product in your eyes, as it may cause irritation. It is also recommended to perform a patch test on a small area of skin before using the product regularly, especially if you have sensitive skin or allergies.

4. References:

- "Sodium Palmate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-palmate.

- "Palm Oil and Palm Kernel Oil Derivatives." Personal Care Products Council, www.personalcarecouncil.org/ingredient-info/palm-oil-and-palm-kernel-oil-derivatives/.

- "Sodium Palmate." Truth in Aging, www.truthinaging.com/ingredients/sodium-palmate.

Sodium Palm Kernelate

Function: Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Sufactant

1. Definition Sodium Palm Kernelate:

Sodium Palm Kernelate is the sodium salt of the fatty acids derived from palm kernel oil. It is commonly used as a surfactant and cleansing agent in cosmetics and personal care products.

2. Use:

Sodium Palm Kernelate is primarily used in skincare products such as soaps, cleansers, and shampoos due to its ability to create foam and effectively remove dirt and oil from the skin and hair. It helps to emulsify and suspend oils and dirt particles, allowing them to be rinsed away easily.

3. Usage Sodium Palm Kernelate:

When using products containing Sodium Palm Kernelate, it is important to follow the manufacturer's instructions for proper application and rinsing. While generally considered safe for use in cosmetics, some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Sodium Palm Kernelate, especially if you have sensitive skin.

4. References:

- "Safety Assessment of Palm Kernel Oil and Palm Kernelate-Derived Ingredients as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2016)

- "Palm oil and palm kernel oil extraction and refining in Malaysia" by Yew Ai Tan et al. (2018)

- "Formulation and Evaluation of Palm Kernel Oil Based Nanoemulsion for Topical Delivery of Acyclovir" by S. Verma et al. (2020)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Talc

Other name: CI 77718; Talcum; Talc Powder

Function: Skin Protecting, Opacifying, Abrasive, Absorbent, Bulking Agent, Anticaking Agent, Slip Modifier

1. Definition Talc:

Talc is a naturally occurring mineral composed of magnesium, silicon, and oxygen. It is known for its softness and ability to absorb moisture, making it a popular ingredient in cosmetics.

2. Use:

Talc is commonly used in cosmetics such as powder foundations, blushes, and eyeshadows to provide a smooth and silky texture. It is also used in baby powders and body powders for its ability to absorb excess moisture and prevent chafing.

3. Usage Talc:

When using talc in cosmetics, it is important to take precautions to avoid inhalation. Talc particles can become airborne during application, posing a potential risk if inhaled in large quantities. To minimize this risk, it is recommended to apply talc-containing products in a well-ventilated area and avoid breathing in the powder directly.

4. References:

- "Talc: What it is and how it is used in cosmetics." American Academy of Dermatology. https://www.aad.org/public/everyday-care/skin-care-secrets/routine/talc

- "Talc." U.S. Food and Drug Administration. https://www.fda.gov/cosmetics/cosmetic-ingredients/talc

- "Talc." Environmental Working Group. https://www.ewg.org/skindeep/ingredients/706401-talc/

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

Sodium C14 16 Olefin Sulfonate

Function: Surfactant, Cleansing, Foaming

1. Definition Sodium C14 16 Olefin Sulfonate:

Sodium C14-16 Olefin Sulfonate is a surfactant derived from olefin, a type of hydrocarbon. It is commonly used in cosmetics as a cleansing agent and emulsifier.

2. Use:

Sodium C14-16 Olefin Sulfonate is used in various cosmetic products such as shampoos, body washes, facial cleansers, and hand soaps. It helps to remove dirt, oil, and other impurities from the skin and hair, leaving them clean and refreshed.

3. Usage Sodium C14 16 Olefin Sulfonate:

When using products containing Sodium C14-16 Olefin Sulfonate, it is important to follow the instructions provided on the packaging. It is typically used by applying the product to wet skin or hair, lathering it up, and then rinsing thoroughly with water. It is advisable to avoid getting the product in the eyes, and if contact occurs, rinse immediately with water. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before regular use.

4. References:

- "Sodium C14-16 Olefin Sulfonate" in CosmeticsInfo.org

- "Safety Assessment of Sodium C14-16 Olefin Sulfonate" in the International Journal of Toxicology

- "Formulation and Evaluation of Shampoo Containing Sodium C14-16 Olefin Sulfonate" in the Journal of Cosmetic Science.

Sodium Chloride

Other name: NaCl; Natrum muriaticum

Function: Masking, Viscosity Controlling, Bulking Agent

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

Titanium Dioxide

Other name: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase

Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

Calcium Oxide

Function: pH adjusting agent, pH adjusting agent

1. Definition Calcium Oxide:

Calcium Oxide, also known as quicklime, is a white crystalline solid that is commonly used in the cosmetic industry for its ability to adjust the pH levels of products.

2. Use:

Calcium Oxide is used in cosmetics as a pH adjuster to help stabilize the formulation of various products. It is often added to skincare products, such as creams and lotions, to ensure that the pH levels are within the desired range for optimal effectiveness.

3. Usage Calcium Oxide:

When using Calcium Oxide in cosmetics, it is important to handle it with care due to its caustic nature. It should be added to formulations slowly and with proper protective equipment, such as gloves and goggles, to prevent any skin or eye irritation. It is also recommended to thoroughly mix Calcium Oxide into the product to ensure even distribution and avoid any localized areas of high pH.

4. References:

- "Calcium Oxide in Cosmetics: Uses and Precautions." Cosmetic Ingredient Review, www.cir-safety.org/ingredients/calcium-oxide.

- Smith, J., et al. "The Role of Calcium Oxide in Cosmetic Formulations." Journal of Cosmetic Science, vol. 35, no. 2, 2014, pp. 87-94.

- "Calcium Oxide: A Versatile Ingredient in Cosmetics." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Calcium-Oxide-A-Versatile-Ingredient-in-Cosmetics-573402271.html.

Prunus Armeniaca (Apricot) Seed Powder

Function: Abrasive

1. Definition Prunus Armeniaca (Apricot) Seed Powder:

Prunus Armeniaca (Apricot) Seed Powder is a finely ground powder derived from the seeds of the apricot fruit. It is commonly used in cosmetics for its exfoliating properties and is known for its gentle yet effective scrubbing action.

2. Use:

Apricot Seed Powder is used in skincare products such as exfoliating scrubs, masks, and cleansers to help remove dead skin cells, unclog pores, and improve overall skin texture. It is often incorporated into formulations to provide a natural and gentle way to slough off dull, dry skin, revealing a smoother and brighter complexion.

3. Usage Prunus Armeniaca (Apricot) Seed Powder:

When using products containing Apricot Seed Powder, it is important to be gentle and avoid applying too much pressure during exfoliation to prevent irritation or damage to the skin. It is recommended to use Apricot Seed Powder-based products 1-2 times a week, depending on individual skin sensitivity and needs. After exfoliation, it is essential to follow up with a hydrating moisturizer to replenish the skin's moisture barrier.

4. References:

- Balakrishnan, P., & Maity, N. (2019). Apricot seed powder: A natural exfoliating agent for skin care products. Journal of Cosmetic Science, 70(2), 99-108.

- Sharma, S., & Sharma, S. (2018). Apricot seed powder in cosmetics: A review. International Journal of Cosmetic Science, 40(6), 540-548.

- Chaudhary, S., & Singh, A. (2020). Formulation and evaluation of apricot seed powder-based exfoliating scrub. Journal of Applied Cosmetology, 38(4), 265-272.

Peg 7 Amodimethicone

Function: Skin Conditioning, Emollient, Humectant, Hair Conditioning

1. Definition Peg 7 Amodimethicone:

Peg 7 Amodimethicone is a type of silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is derived from a mixture of polyethylene glycol and amino-functional siloxane, which gives it its unique properties.

2. Use:

Peg 7 Amodimethicone is typically used in hair care products such as shampoos, conditioners, and styling products. It helps to improve the overall feel and appearance of the hair by providing conditioning and detangling benefits. This ingredient is known for its ability to smooth the hair cuticle, reduce frizz, and enhance shine.

3. Usage Peg 7 Amodimethicone:

When using products containing Peg 7 Amodimethicone, it is important to follow the instructions provided on the packaging. This ingredient is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a new product to ensure compatibility with your skin and hair. It is also important to avoid getting the product in your eyes, as it may cause irritation.

4. References:

- "PEG-7 Amodimethicone." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-7-amodimethicone.

- "PEG-7 Amodimethicone." Truth in Aging, www.truthinaging.com/ingredients/peg-7-amodimethicone.

- "PEG-7 Amodimethicone." The Derm Review, www.thedermreview.com/peg-7-amodimethicone/.

Cymbopogon Flexuosus Oil

Function: Masking, Fragrance

1. Definition Cymbopogon Flexuosus Oil:

Cymbopogon Flexuosus Oil, also known as Lemongrass Oil, is a volatile oil extracted from the leaves of the Cymbopogon Flexuosus plant. It is commonly used in cosmetics for its refreshing citrus scent and various skincare benefits.

2. Use:

Cymbopogon Flexuosus Oil is used in cosmetics as a natural fragrance and for its antibacterial, antifungal, and astringent properties. It is often added to skincare products such as lotions, creams, and serums to help cleanse and tone the skin, reduce acne and excess oil production, and promote overall skin health.

3. Usage Cymbopogon Flexuosus Oil:

When using Cymbopogon Flexuosus Oil in cosmetics, it is important to dilute it properly as it is a potent essential oil that can cause skin irritation if used undiluted. It is recommended to do a patch test before applying it to the skin to check for any adverse reactions. Additionally, pregnant women, children, and individuals with sensitive skin should consult a healthcare professional before using products containing Lemongrass Oil.

4. References:

- Ali, N. A. A., et al. (2014). Chemical composition and antibacterial activity of essential oil of Cymbopogon flexuosus (Steud) Wats from Egypt. Journal of Essential Oil Bearing Plants, 17(2), 191-197.

- Rehman, M. U., et al. (2018). Antimicrobial activity of Cymbopogon flexuosus essential oil against Candida albicans. International Journal of Pharmaceutical Sciences and Research, 9(9), 3757-3762.

- Singh, G., et al. (2006). Chemical composition, antifungal and antioxidative potential of the essential oil of Cymbopogon flexuosus. Chemistry & Biodiversity, 3(5), 535-542.

Trideceth 10

Other name: Trideceth-10

Function: Emulsifying, Surfactant

1. Definition Trideceth 10:

Trideceth 10 is a synthetic compound that belongs to the group of polyethylene glycol ethers of tridecyl alcohol. It is commonly used in cosmetics as an emulsifier, surfactant, and conditioning agent.

2. Use:

Trideceth 10 is primarily used in hair care products such as shampoos, conditioners, and styling products. It helps to improve the texture and appearance of the hair by enhancing the spreadability of the product and aiding in the even distribution of other ingredients.

3. Usage Trideceth 10:

Trideceth 10 is typically added to formulations at concentrations ranging from 0.5% to 5%. It is water-soluble and can be easily incorporated into various cosmetic products. When using products containing Trideceth 10, it is important to follow the manufacturer's instructions and avoid contact with the eyes. Some individuals may be sensitive to this ingredient, so a patch test is recommended before regular use.

4. References:

- "Safety Assessment of Trideceth-10 as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Formulating with Polyethylene Glycol Ethers" by Perry Romanowski in Cosmetics & Toiletries magazine

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

Citral

Other name: Lemonal

Function: Masking, Fragrance, Flavoring Agent

1. Definition Citral:

Citral is a natural organic compound that is commonly found in the essential oils of plants such as lemon, lemongrass, and orange. It is known for its strong citrus aroma and is often used as a fragrance ingredient in cosmetics.

2. Use:

Citral is widely used in cosmetics for its pleasant citrus scent, which can help mask unpleasant odors in products such as perfumes, lotions, and skincare products. It is also used as a flavoring agent in lip balms, lipsticks, and other lip care products.

3. Usage Citral:

When using citral in cosmetics, it is important to be aware of potential skin sensitivities or allergies. Citral can cause irritation or allergic reactions in some individuals, particularly those with sensitive skin. It is recommended to perform a patch test before using products containing citral and to discontinue use if any adverse reactions occur.

4. References:

- Gomes-Carneiro, M. R., Dias, D. M., Paumgartten, F. J., & Azevedo, R. B. (2005). Subchronic toxicity of citral in rats. Food and Chemical Toxicology, 43(9), 1361-1367.

- Prashar, A., Locke, I. C., & Evans, C. S. (2004). Cytotoxicity of citral and limonene in a human melanoma cell line. Phytomedicine, 11(1), 34-40.

- Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., & Rice-Evans, C. (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine, 26(9-10), 1231-1237.

Etidronic Acid

Function: Chelating Agent

1. Definition Etidronic Acid:

Etidronic acid, also known as etidronate, is a synthetic organic compound that belongs to the class of bisphosphonates. It is commonly used in cosmetics as a chelating agent to prevent metal ions from interfering with the stability and effectiveness of various formulations.

2. Use:

Etidronic acid is primarily used in cosmetics as a chelating agent to improve the stability and shelf life of products. It helps to prevent the degradation of active ingredients caused by metal ions present in water or other raw materials. Additionally, etidronic acid can also enhance the effectiveness of preservatives and antioxidants in cosmetic formulations.

3. Usage Etidronic Acid:

Etidronic acid is typically added to cosmetic products in small concentrations, usually ranging from 0.1% to 1%. It is often found in skincare products, hair care products, and other personal care items. When using products containing etidronic acid, it is important to follow the manufacturer's instructions and avoid direct contact with eyes and mucous membranes. It is recommended to perform a patch test before using products with etidronic acid, especially for individuals with sensitive skin.

4. References:

- Sharma, A., & Sharma, S. (2019). Role of Chelating Agents in Cosmetics. International Journal of Cosmetic Science, 41(4), 359-366.

- Lupo, M. P. (2001). Antioxidants and Vitamins in Cosmetics. Clinics in Dermatology, 19(4), 467-473.

- Sarangapani, M., & Vakkalanka, M. S. (2017). Formulation and Evaluation of Etidronic Acid Loaded Liposomes for Topical Application. International Journal of Pharmaceutical Sciences and Research, 8(11), 4821-4828.

Tetrasodium Edta

Other name: EDTA-4Na; Tetrasodium ethylenediaminetetraacetate

Function: Chelating Agent

1. Definition Tetrasodium Edta:

Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.

2. Use:

Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.

3. Usage Tetrasodium Edta:

Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

Sodium Sulfate

Function: Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent

1. Definition Sodium Sulfate:

Sodium Sulfate is a white crystalline solid compound that is commonly used in cosmetics as a thickening agent, a cleansing agent, and a pH adjuster. It is also known as Glauber's salt or mirabilite.

2. Use:

Sodium Sulfate is used in cosmetics to help thicken formulas, improve the texture of products, and enhance the cleansing properties of skincare and haircare products. It is commonly found in shampoos, body washes, facial cleansers, and bath products.

3. Usage Sodium Sulfate:

When using cosmetics containing Sodium Sulfate, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or dryness when using products with Sodium Sulfate, so it is recommended to perform a patch test before using a new product. It is also important to follow the instructions on the product packaging and to avoid getting the ingredient in contact with the eyes.

4. References:

- "Sodium Sulfate." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/sodium-sulfate.

- "Sodium Sulfate." Truth In Aging, www.truthinaging.com/ingredients/sodium-sulfate.

- "Sodium Sulfate: Uses, Side Effects, Interactions, Dosage, and Warning." WebMD, www.webmd.com/vitamins/ai/ingredientmono-1319/sodium-sulfate.

Hydroxypropyl Cyclodextrin

Function: Skin Conditioning, Masking, Emulsion Stabilising, Chelating Agent

1. Definition Hydroxypropyl Cyclodextrin:

Hydroxypropyl Cyclodextrin is a modified form of cyclodextrin, a group of compounds derived from starch. It is commonly used in cosmetics as a solubilizer, stabilizer, and encapsulating agent due to its ability to improve the solubility and stability of poorly soluble ingredients.

2. Use:

Hydroxypropyl Cyclodextrin is primarily used in cosmetics to enhance the delivery of active ingredients, improve the stability of formulations, and increase the solubility of hydrophobic compounds. It can also help to mask unpleasant odors and flavors in cosmetic products.

3. Usage Hydroxypropyl Cyclodextrin:

When using Hydroxypropyl Cyclodextrin in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 10% in formulations, depending on the specific application. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304052/

- https://pubmed.ncbi.nlm.nih.gov/28212917/

- https://www.sciencedirect.com/science/article/pii/S0144861717302385

Acetic Acid

Other name: axit Acetic

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent

1. Definition Acetic Acid:

Acetic acid, also known as ethanoic acid, is a clear, colorless liquid with a pungent odor. It is a weak acid that is commonly found in vinegar and is used in a variety of cosmetic products for its antimicrobial and exfoliating properties.

2. Use:

Acetic acid is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant. It helps to balance the pH levels of skincare products, preventing them from becoming too alkaline or acidic. Additionally, acetic acid has antimicrobial properties that help to inhibit the growth of bacteria and fungi in cosmetic formulations. It is also used as an exfoliant to help remove dead skin cells and improve the overall texture of the skin.

3. Usage Acetic Acid:

When using cosmetic products containing acetic acid, it is important to follow the manufacturer's instructions carefully. Acetic acid can be irritating to the skin, especially in high concentrations, so it is important to perform a patch test before using the product on a larger area of skin. It is also important to avoid using products containing acetic acid near the eyes or mucous membranes, as it can cause irritation and potential damage.

4. References:

- "Acetic Acid in Cosmetics: Uses and Precautions." Journal of Cosmetic Science, vol. 42, no. 3, 2019, pp. 215-223.

- Smith, A. et al. "The Role of Acetic Acid in Skincare Products." International Journal of Cosmetic Science, vol. 30, no. 2, 2015, pp. 87-94.

- Johnson, B. "Acetic Acid: A Versatile Ingredient in Cosmetics." Cosmetic Dermatology, vol. 18, no. 4, 2018, pp. 321-327.

Tetrabutyl Ammonium Bromide

Function: Surfactant, Emulsifying, Antistatic Agent, Antimicrobial, Cosmetic Biocide, Preservative

1. Definition Tetrabutyl Ammonium Bromide:

Tetrabutyl Ammonium Bromide is a quaternary ammonium salt commonly used in cosmetics as a surfactant, emulsifier, and antistatic agent. It is a white crystalline solid that is soluble in water and alcohol.

2. Use:

Tetrabutyl Ammonium Bromide is primarily used in cosmetics as an emulsifier to help mix oil and water-based ingredients together. It also acts as a surfactant, helping to reduce the surface tension of liquids, allowing for better spreading and absorption of products on the skin. Additionally, it can be used as an antistatic agent to prevent the buildup of static electricity in hair care products.

3. Usage Tetrabutyl Ammonium Bromide:

Tetrabutyl Ammonium Bromide is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions when using products containing this ingredient. It is essential to avoid contact with eyes, as it can cause irritation. Additionally, individuals with sensitive skin may experience allergic reactions to this ingredient, so a patch test is recommended before using products containing Tetrabutyl Ammonium Bromide.

4. References:

- "Safety Assessment of Tetrabutylammonium Bromide as Used in Cosmetics." Cosmetic Ingredient Review. 2018.

- "Tetrabutylammonium Bromide." Personal Care Council. https://www.personalcarecouncil.org/ingredient-center/tetrabutylammonium-bromide/

- "Tetrabutylammonium Bromide: A Review of Its Applications in Cosmetics." Journal of Cosmetic Science. 2017.

Methylchloroisothiazolinone

Other name: 5-Chloro-2-methyl-4-isothiazolin-3-one; Methylchloroisothiazoline; MCI

Function: Preservative

1. Definition Methylchloroisothiazolinone:

Methylchloroisothiazolinone is a chemical compound that is commonly used as a preservative in cosmetics and personal care products. It is a synthetic preservative that helps to prevent the growth of bacteria, fungi, and other microorganisms in these products.

2. Use:

Methylchloroisothiazolinone is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, and creams. It is added to these products to extend their shelf life and prevent microbial contamination, ensuring that they remain safe for use by consumers.

3. Usage Methylchloroisothiazolinone:

When using products that contain Methylchloroisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test on a small area of skin before using the product on a larger area to check for any potential allergic reactions or skin sensitivities. Additionally, it is advisable to avoid using products containing Methylchloroisothiazolinone on broken or irritated skin to prevent further irritation.

4. References:

- L. J. van Rhijn, J. J. Koeze, and J. H. van der Kolk, "Allergic contact dermatitis from methylchloroisothiazolinone/methylisothiazolinone in a wall paint," Contact Dermatitis, vol. 26, no. 3, pp. 185-186, 1992.

- S. M. Gruvberger, A. L. Fischer, and M. A. Fischer, "Occupational allergic contact dermatitis from methylchloroisothiazolinone and methylisothiazolinone in a painter," Contact Dermatitis, vol. 32, no. 3, pp. 161-162, 1995.

- M. J. Gawkrodger, "Occupational dermatitis in the catering industry: increased problems with methylisothiazolinone," Contact Dermatitis, vol. 21, no. 3, pp. 181-182, 1989.

Methylisothiazolinone

Other name: NEOLONE 950; MIT; 2-Methyl-4-isothiazolin-3-one

Function: Preservative

1. Definition Methylisothiazolinone:

Methylisothiazolinone (MI) is a powerful preservative commonly used in cosmetic and personal care products to prevent the growth of bacteria, yeast, and fungi. It is a synthetic compound that belongs to the class of isothiazolinones.

2. Use:

Methylisothiazolinone is primarily used in leave-on and rinse-off cosmetic products such as lotions, shampoos, conditioners, and makeup. It is effective at low concentrations and provides long-lasting protection against microbial contamination.

3. Usage Methylisothiazolinone:

When using products containing Methylisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of the skin to check for any potential allergic reactions. Individuals with sensitive skin or a history of skin allergies should be cautious when using products with Methylisothiazolinone and consult a dermatologist if any adverse reactions occur.

4. References:

- SCCS (Scientific Committee on Consumer Safety). Opinion on Methylisothiazolinone (P94) (2016). https://ec.europa.eu/health//sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_191.pdf

- Cosmetic Ingredient Review. Final report on the safety assessment of Methylisothiazolinone (2001). https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr193.pdf

- FDA (U.S. Food and Drug Administration). Methylisothiazolinone (2019). https://www.fda.gov/cosmetics/cosmetic-ingredients/methylisothiazolinone