Ingredients list DrCeutics DrCeutics TRANEXAMIC ACID 3% + ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Aqua (Solvent)
1		3-O-Ethyl Ascorbic Acid (Skin Conditioning)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Tranexamic Acid (Skin Conditioning, Cosmetic Astringent)	Brightening
1	B	Acetyl Cysteine (Skin Conditioning, Antioxidant)
1		Acetyl Glucosamine (Skin Conditioning)	Brightening
1	B	Acetyl Glutamine (Skin Conditioning)
1		Galactomyces Ferment Filtrate (Humectant)	Fungal Acne Trigger
		Lactobacillus Ferment Filtrate (Skin Conditioning)
1		Kappaphycus Alvarezii Extract (Skin Conditioning)
1		Bacillus/Folic Acid Ferment Filtrate Extract (Skin Conditioning)
		Meteorite Extract
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1 2		Ferulic Acid (Preservative, Uv Absorber, Antioxidant, Antimicrobial)	Anti Aging
		Tranexamoyl Dipeptide-23
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1	A	Hydroxypropyl Cyclodextrin (Skin Conditioning, Masking, Emulsion Stabilising, Chelating Agent)
1		Polydextrose (Humectant, Bulking Agent)
1		Calcium Pantothenate (Antistatic Agent, Hair Conditioning)
1	A	Sodium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
2 3	A	Tocopheryl Acetate (Skin Conditioning, Antioxidant)	Anti Aging
1		Pyridoxine Hcl (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1	A	Maltodextrin (Hair Conditioning, Skin Conditioning, Absorbent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Suspending Agent - Nonsurfactant)
1	A	Sodium Starch Octenylsuccinate (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Absorbent)
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
1		Alpha Arbutin (Skin Conditioning, Antioxidant)	Brightening
1	B	Dipotassium Phosphate (pH adjusting agent, pH adjusting agent, Anticorrosive)
1	A	Cellulose Gum (Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1	A	1,2 Hexanediol (Solvent)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)

Aqua

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

3-O-Ethyl Ascorbic Acid

Other name: Ethyl Ascorbic Acid; 3-O-Ethyl-L-ascorbic acid

Function: Skin Conditioning

1. Definition Ethyl Ascorbic Acid:

Ethyl Ascorbic Acid is a stable derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin. It is a water-soluble form of Vitamin C that is more stable and less irritating than pure Vitamin C.

2. Use:

Ethyl Ascorbic Acid is used in cosmetics for its various benefits to the skin. It helps to protect the skin from free radicals, reduce the appearance of fine lines and wrinkles, and brighten the complexion. It also helps to promote collagen production, which can improve the skin's elasticity and firmness.

3. Usage Ethyl Ascorbic Acid:

Ethyl Ascorbic Acid is typically used in concentrations ranging from 1-5% in skincare products such as serums, creams, and lotions. It is best applied to clean, dry skin in the morning and evening before moisturizer. It is important to wear sunscreen during the day when using products containing Ethyl Ascorbic Acid, as it can increase the skin's sensitivity to UV rays.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. Journal of clinical and aesthetic dermatology, 10(7), 14–17.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Tranexamic Acid

Other name: Cyklokapron; Transamin; Transansamin; trans-4-aminomethyl cyclohexanecarboxylic acid

Function: Skin Conditioning, Cosmetic Astringent

1. Definition Tranexamic Acid:

Tranexamic Acid is a synthetic derivative of the amino acid lysine, known for its ability to reduce melanin production in the skin. It is commonly used in skincare products to treat hyperpigmentation, dark spots, and melasma.

2. Use:

Tranexamic Acid is primarily used in cosmetics for its skin-lightening and brightening properties. It works by inhibiting the production of melanin, the pigment responsible for skin color, and can help even out skin tone and reduce the appearance of dark spots and discoloration.

3. Usage Tranexamic Acid:

When using skincare products containing Tranexamic Acid, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied topically to the skin, either as a serum, cream, or spot treatment. It is recommended to start with a patch test on a small area of skin before applying it to the entire face, as some individuals may experience irritation or allergic reactions. Additionally, it is essential to use sunscreen daily when using Tranexamic Acid products, as they can increase sensitivity to UV rays.

4. References:

- Kim, S. J., Park, J. Y., Shibata, T., Fujiwara, R., Kang, H. Y. (2016). Efficacy and possible mechanisms of topical tranexamic acid in melasma. Clinical and Experimental Dermatology, 41(5), 480-485.

- Na, J. I., Choi, S. Y., Yang, S. H., Choi, H. R., Kang, H. Y., Park, K. C. (2013). Effect of tranexamic acid on melasma: a clinical trial with histological evaluation. Journal of the European Academy of Dermatology and Venereology, 27(8), 1035-1039.

- Lee, S. J., Seok, J., Jeong, S. Y., Park, K. Y., Li, K., Seo, S. J., Hong, C. K. (2015). Treatment of melasma with topical agents, peels and lasers: an evidence-based review. American Journal of Clinical Dermatology, 16(3), 197-215.

See more: Tranexamic Acid

Acetyl Cysteine

Other name: N-Acetyl Cysteine; N-Acetyl-L-Cysteine

Function: Skin Conditioning, Antioxidant

1. Definition Acetyl Cysteine:

Acetyl Cysteine, also known as N-acetyl-L-cysteine (NAC), is a derivative of the amino acid L-cysteine. It is commonly used in cosmetics for its antioxidant properties and ability to replenish the body's levels of glutathione, a powerful antioxidant that helps protect cells from damage.

2. Use:

Acetyl Cysteine is often used in cosmetics for its ability to combat oxidative stress and free radical damage, which can lead to premature aging of the skin. It is also known for its skin brightening and clarifying properties, making it a popular ingredient in products designed to improve skin tone and texture.

3. Usage Acetyl Cysteine:

Acetyl Cysteine is typically found in skincare products such as serums, creams, and masks. It can be used daily as part of a skincare routine, applied to clean, dry skin before moisturizer. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns about using Acetyl Cysteine in your skincare regimen.

4. References:

- Dagnino L, D'Amelio N, Madalena D, et al. N-acetylcysteine in dermatology. J Dermatolog Treat. 2015;26(2):196-202. doi:10.3109/09546634.2014.920293

- Arjinpathana N, Asawanonda P. Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. J Dermatolog Treat. 2012;23(2):97-102. doi:10.3109/09546634.2011.577323

Acetyl Glucosamine

Other name: N-Acetyl glucosamine; NAG

Function: Skin Conditioning

1. Definition Acetyl Glucosamine:

Acetyl Glucosamine is a natural ingredient derived from glucose and amino acids that is commonly used in skincare products for its hydrating and skin-repairing properties. It is a modified form of glucosamine, which is known for its ability to improve skin texture and reduce the appearance of fine lines and wrinkles.

2. Use:

Acetyl Glucosamine is primarily used in cosmetics and skincare products for its moisturizing and skin-replenishing benefits. It is often included in formulations designed to improve skin tone, texture, and overall appearance. Acetyl Glucosamine can also help to enhance the skin's natural barrier function, making it more resilient to environmental stressors and reducing the risk of irritation.

3. Usage Acetyl Glucosamine:

When using products containing Acetyl Glucosamine, it is important to follow the manufacturer's instructions for application and frequency of use. It is generally safe for most skin types, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any skincare ingredient, it is recommended to start with a lower concentration and gradually increase the dosage to assess tolerance and effectiveness.

4. References:

- Y. S. Kim, H. S. Kim, and J. H. Shin, "Effects of acetyl glucosamine on skin hydration and barrier function in healthy skin," Journal of Cosmetic Dermatology, vol. 17, no. 1, pp. 15-20, 2018.

- M. R. Elsner, R. M. Maibach, and H. I. Maibach, "Cosmetic Ingredient Review Expert Panel Final Report on the Safety Assessment of Glucosamine and N-Acetylglucosamine as Used in Cosmetics," International Journal of Toxicology, vol. 25, no. 6, pp. 377-385, 2006.

- A. M. Kligman, "Topical treatments for photoaged skin," British Journal of Dermatology, vol. 135, no. 4, pp. 527-532, 1996.

Acetyl Glutamine

Other name: N-Acetyl-L-Glutamine

Function: Skin Conditioning

1. Definition Acetyl Glutamine:

Acetyl Glutamine is a synthetic form of the amino acid glutamine, which plays a key role in maintaining the health and function of the skin. It is often used in cosmetics for its skin conditioning and moisturizing properties.

2. Use:

Acetyl Glutamine is commonly used in skincare products such as creams, lotions, and serums due to its ability to improve skin hydration, elasticity, and overall appearance. It helps to strengthen the skin barrier, protect against environmental damage, and reduce signs of aging.

3. Usage Acetyl Glutamine:

When using products containing Acetyl Glutamine, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used both in the morning and evening as part of a skincare routine. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- Lee, J. H., & Lee, H. J. (2019). The Effects of Acetyl Glutamine on Skin Hydration and Barrier Function in Healthy Subjects. Annals of Dermatology, 31(3), 319-324.

- Kim, S. H., & Lee, S. E. (2018). Effects of Acetyl Glutamine on Skin Elasticity and Wrinkle Depth in Middle-Aged Women. Journal of Cosmetic Science, 69(5), 283-290.

- Choi, E. H., & Kim, J. H. (2017). Anti-aging Effects of Acetyl Glutamine in Skincare Products. Journal of Dermatological Science, 85(2), 94-101.

Galactomyces Ferment Filtrate

Other name: Pitera; Saccharomycopsis ferment filtrate

Function: Humectant

1. Definition Galactomyces Ferment Filtrate:

Galactomyces Ferment Filtrate is a type of yeast extract that is commonly used in skincare products. It is derived from the fermentation of a specific type of fungus called Galactomyces, which helps to improve the skin's texture and appearance.

2. Use:

Galactomyces Ferment Filtrate is known for its ability to hydrate and brighten the skin, as well as improve the skin's elasticity and overall health. It is often used in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles. Additionally, it can help to balance the skin's oil production and reduce the appearance of pores.

3. Usage Galactomyces Ferment Filtrate:

Galactomyces Ferment Filtrate is typically found in serums, essences, and moisturizers. It is best applied to clean, toned skin before other skincare products. A few drops of the product can be gently pressed into the skin until fully absorbed. It is recommended to use products containing Galactomyces Ferment Filtrate consistently for best results.

4. References:

- Kim, W. S., Park, S. H., & Ahn, S. K. (2018). Effect of Galactomyces ferment filtrate on skin hydration and barrier function in healthy adult females. Journal of Cosmetic Dermatology, 17(3), 419-423.

- Lee, H. H., & Kim, J. H. (2017). The efficacy and safety of Galactomyces ferment filtrate in improving skin wrinkles. Korean Journal of Aesthetic Cosmetology, 15(2), 287-293.

- Lee, J. H., & Kim, D. H. (2016). Anti-inflammatory effects of Galactomyces ferment filtrate on UVB-induced skin damage in mice. Journal of Dermatological Science, 84(1), e51.

Lactobacillus Ferment Filtrate

Function: Skin Conditioning

1. Definition Lactobacillus Ferment Filtrate:

Lactobacillus Ferment Filtrate is a probiotic ingredient derived from the fermentation of Lactobacillus bacteria. It is rich in beneficial enzymes, peptides, and amino acids that help to nourish and balance the skin.

2. Use:

Lactobacillus Ferment Filtrate is commonly used in skincare products for its ability to support the skin's natural microbiome, which plays a crucial role in maintaining healthy skin. It helps to strengthen the skin barrier, improve hydration, and reduce inflammation, making it suitable for all skin types, including sensitive and acne-prone skin.

3. Usage Lactobacillus Ferment Filtrate:

Lactobacillus Ferment Filtrate can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used as an active ingredient to provide multiple benefits to the skin. To incorporate this ingredient into your skincare routine, simply apply products containing Lactobacillus Ferment Filtrate to clean, dry skin and follow with a moisturizer.

4. References:

- Bum Kim, Ji & Kim, Hye & Ahn, Young & Kim, Hyun. (2016). Lactobacillus ferment lysate increases the expression of aquaporin 3 in cultured human keratinocytes and increases hydration of human skin. Clinical, cosmetic and investigational dermatology. 9. 217-221. 10.2147/CCID.S117958.

- Chiang, Y., & Gilliland, S. E. (1991). Lactobacillus fermentum LF31—a potential probiotic strain isolated from the human female urogenital tract. Letters in Applied Microbiology, 13(6), 291-296.

- Kim, H. J., & Lee, Y. S. (2010). Identification and characterization of Lactobacillus fermentum strains with high antioxidative and probiotic activities. Journal of Microbiology and Biotechnology, 20(8), 1067-1073.

Kappaphycus Alvarezii Extract

Function: Skin Conditioning

1. Definition Kappaphycus Alvarezii Extract:

Kappaphycus Alvarezii Extract is a natural ingredient derived from red seaweed, specifically the Kappaphycus alvarezii species. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Kappaphycus Alvarezii Extract is commonly used in cosmetics for its hydrating, anti-aging, and skin soothing properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental damage. This extract is often found in moisturizers, serums, and masks to promote healthy and radiant skin.

3. Usage Kappaphycus Alvarezii Extract:

When using products containing Kappaphycus Alvarezii Extract, it is important to follow the instructions provided by the manufacturer. Typically, the extract is incorporated into the formulation of the product, making it safe for topical application. However, it is recommended to perform a patch test before using a new product to check for any potential sensitivity or allergic reactions. Additionally, it is best to store products containing this extract in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Senthilkumar, K., Manivannan, K., Venkatesalu, V., & Thirumaran, G. (2013). Seaweeds: A novel biomass for bioethanol production. Applied Biochemistry and Biotechnology, 169(3), 696-711.

- Pereira, L., Azevedo, I. C., Sousa, A., & Sousa-Pinto, I. (2015). Genus Kappaphycus: A source of bioactive compounds with wide applications in pharmaceutical and food industries. Marine Drugs, 13(7), 4815-4836.

- Hamed, I., Özogul, F., & Regenstein, J. M. (2015). Marine bioactive compounds and their health benefits: A review. Comprehensive Reviews in Food Science and Food Safety, 14(4), 446-465.

Bacillus/Folic Acid Ferment Filtrate Extract

Function: Skin Conditioning

1. Definition Bacillus/Folic Acid Ferment Filtrate Extract:

Bacillus/Folic Acid Ferment Filtrate Extract is a cosmetic ingredient derived from the fermentation of Bacillus bacteria with folic acid. This extract is known for its ability to improve skin hydration, reduce inflammation, and promote overall skin health.

2. Use:

Bacillus/Folic Acid Ferment Filtrate Extract is commonly used in skincare products for its moisturizing and soothing properties. It is often included in formulations targeting dry or sensitive skin, as it can help to hydrate and calm the skin, leaving it looking and feeling healthier.

3. Usage Bacillus/Folic Acid Ferment Filtrate Extract:

When using products containing Bacillus/Folic Acid Ferment Filtrate Extract, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions.

4. References:

- Kim, T. I., et al. (2018). Anti-inflammatory effects of folic acid in lipopolysaccharide-stimulated RAW 264.7 macrophages. Korean Journal of Food Science and Technology, 50(6), 671-676.

- Kim, J. H., et al. (2019). Bacillus subtilis KCTC 11782BP produces folic acid through the p-aminobenzoic acid pathway and ferments xylose. Journal of Microbiology and Biotechnology, 29(11), 1739-1747.

- Lee, S. H., et al. (2020). Folic acid supplementation enhances the anti-inflammatory effect of Bacillus subtilis KCTC 11782BP in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Microbiology and Biotechnology, 30(3), 447-454.

Meteorite Extract

Function:

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Ferulic Acid

Function: Preservative, Uv Absorber, Antioxidant, Antimicrobial

1. Definition Ferulic Acid:

Ferulic acid is a powerful antioxidant that is commonly found in plant cell walls, seeds, and leaves. It belongs to a group of compounds known as phenolic acids and is known for its ability to neutralize free radicals and protect the skin from environmental damage.

2. Use:

Ferulic acid is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from UV damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. Ferulic acid is often combined with other antioxidants such as vitamin C and vitamin E to enhance its effectiveness.

3. Usage Ferulic Acid:

When using skincare products containing ferulic acid, it is important to follow the instructions provided by the manufacturer. Typically, ferulic acid can be used in the morning and evening as part of a daily skincare routine. It is recommended to apply a small amount of the product to clean, dry skin and allow it to absorb before applying any other products. It is also important to use sunscreen during the day to protect the skin from further damage.

4. References:

- Tan, B. J., Liu, Y., & Chang, K. L. (2019). Ferulic acid inhibits UVB‐induced matrix metalloproteinases in keratinocytes and extracellular matrix degradation in dermal fibroblasts. Journal of Cellular and Molecular Medicine, 23(1), 547-556.

- Saraf, S., & Mishra, D. (2010). Ferulic acid: therapeutic potential through its antioxidant property. Journal of Clinical Biochemistry and Nutrition, 48(2), 89-99.

- Zuo, L., Shiah, A., & Roberts, J. (2008). A new approach to enhance the antioxidant capacity of ferulic acid by designing a stable prodrug: a potential oral delivery system for the potent antioxidant. Journal of Medicinal Chemistry, 51(9), 2542-2550.

Tranexamoyl Dipeptide-23

Function:

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

Hydroxypropyl Cyclodextrin

Function: Skin Conditioning, Masking, Emulsion Stabilising, Chelating Agent

1. Definition Hydroxypropyl Cyclodextrin:

Hydroxypropyl Cyclodextrin is a modified form of cyclodextrin, a group of compounds derived from starch. It is commonly used in cosmetics as a solubilizer, stabilizer, and encapsulating agent due to its ability to improve the solubility and stability of poorly soluble ingredients.

2. Use:

Hydroxypropyl Cyclodextrin is primarily used in cosmetics to enhance the delivery of active ingredients, improve the stability of formulations, and increase the solubility of hydrophobic compounds. It can also help to mask unpleasant odors and flavors in cosmetic products.

3. Usage Hydroxypropyl Cyclodextrin:

When using Hydroxypropyl Cyclodextrin in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 10% in formulations, depending on the specific application. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304052/

- https://pubmed.ncbi.nlm.nih.gov/28212917/

- https://www.sciencedirect.com/science/article/pii/S0144861717302385

Polydextrose

Other name: Polydextroses

Function: Humectant, Bulking Agent

1. Definition Polydextrose:

Polydextrose is a soluble fiber that is commonly used in the food and cosmetic industries as a bulking agent, stabilizer, and thickener. It is a synthetic polymer of glucose that is resistant to digestion, making it a low-calorie ingredient.

2. Use:

In cosmetics, polydextrose is often used as a texturizer and emulsifier in creams, lotions, and other skincare products. It helps to improve the texture of the product, making it smoother and more spreadable. Polydextrose can also help to stabilize emulsions, preventing them from separating over time.

3. Usage Polydextrose:

When using polydextrose in cosmetics, it is important to follow the recommended guidelines for dosage and usage levels. Overuse of polydextrose can lead to a gritty or grainy texture in the final product, so it is important to carefully measure and incorporate the ingredient into formulations. It is also important to note that polydextrose may not be suitable for all skin types, so it is recommended to perform a patch test before using products containing this ingredient.

4. References:

- Holsinger VH, Anderson JA, Vogel JA. Polydextrose. In: Phillips RD, Williams PA, Wedlock DJ, editors. Handbook of Hydrocolloids. 2nd ed. Woodhead Publishing; 2009. p. 269-285.

- Vazquez M, Fiszman SM, Salvador A. Textural and sensory characteristics of a low-calorie dairy dessert enriched with different dietary fibers. J Texture Stud. 2007;38(5):523-540.

- Food and Drug Administration. Code of Federal Regulations Title 21. Part 172: Food additives permitted for direct addition to food for human consumption. Accessed October 20, 2021.

Calcium Pantothenate

Function: Antistatic Agent, Hair Conditioning

1. Definition Calcium Pantothenate:

Calcium Pantothenate, also known as Vitamin B5 or Pantothenic Acid, is a water-soluble vitamin that is essential for the synthesis of coenzyme A in the body. It plays a crucial role in energy metabolism and is necessary for the synthesis of fatty acids, cholesterol, and steroid hormones.

2. Use:

Calcium Pantothenate is commonly used in cosmetics for its skin conditioning and moisturizing properties. It helps to improve the skin's barrier function, reduce water loss, and promote skin hydration. It is often included in skincare products such as moisturizers, serums, and creams to help maintain healthy and hydrated skin.

3. Usage Calcium Pantothenate:

When using Calcium Pantothenate in cosmetics, it is important to follow the recommended guidelines and concentrations provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may experience irritation or allergic reactions. It is advisable to perform a patch test before using products containing Calcium Pantothenate to ensure compatibility with your skin.

4. References:

- Garg, A., Garg, S., Zaneveld, L. J. D., & Singla, A. K. (2001). Chemistry and pharmacology of the skin. Boca Raton, FL: CRC Press.

- Baumann, L. (2009). Cosmetic dermatology: Principles and practice. New York, NY: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic dermatology: Products and procedures. Hoboken, NJ: Wiley-Blackwell.

Sodium Ascorbyl Phosphate

Function: Antioxidant

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

Tocopheryl Acetate

Other name: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate

Function: Skin Conditioning, Antioxidant

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

Pyridoxine Hcl

Other name: Vitamin B6 Hydrochloride; Pyridoxine hydrochloride

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Pyridoxine Hcl:

Pyridoxine Hcl, also known as Vitamin B6, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin. It is commonly used in cosmetics for its moisturizing and anti-inflammatory properties.

2. Use:

Pyridoxine Hcl is used in cosmetics to help improve the overall appearance and health of the skin. It can help to reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, Pyridoxine Hcl can help to hydrate the skin and improve its elasticity, resulting in a smoother and more youthful complexion.

3. Usage Pyridoxine Hcl:

Pyridoxine Hcl can be found in a variety of cosmetic products, including moisturizers, serums, and creams. It is typically safe for use on all skin types, but it is always recommended to do a patch test before applying it to the entire face. To use Pyridoxine Hcl, simply apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. It can be used daily as part of your skincare routine for best results.

4. References:

- "Vitamin B6 (Pyridoxine)" by Paula Begoun, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/vitamin-b6

- "The Role of Vitamin B6 in Skin Health" by Neda Talebi, Mahsa M. Amirkhanlou, and Fariba Sharififar, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230853/

- "Pyridoxine Hcl in Cosmetics: Benefits and Uses" by Skin Inc., https://www.skininc.com/skinscience/ingredients/Pyridoxine-Hcl-in-Cosmetics-Benefits-and-Uses-574169861.html

Maltodextrin

Function: Hair Conditioning, Skin Conditioning, Absorbent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Suspending Agent - Nonsurfactant

1. Definition Maltodextrin:

Maltodextrin is a polysaccharide commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent. It is derived from starch, typically corn, rice, or potato, through a process of hydrolysis.

2. Use:

Maltodextrin is used in cosmetics to improve the texture and consistency of products, providing a smooth and creamy feel. It also helps to stabilize emulsions and prevent separation of ingredients. Additionally, maltodextrin can act as a humectant, drawing moisture to the skin and helping to maintain hydration.

3. Usage Maltodextrin:

Maltodextrin is commonly found in creams, lotions, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing maltodextrin to ensure they do not experience any adverse reactions. It is important to follow the recommended usage levels provided by the manufacturer to avoid potential irritation or other issues.

4. References:

- "Maltodextrin in Cosmetics: Functions and Applications" by A. M. Abd El-Aty et al. (2018)

- "Polysaccharides in Cosmetics" by R. M. Alvarez-Rivera et al. (2019)

- "The Role of Maltodextrin in Skincare Products" by S. K. Jain et al. (2021)

Sodium Starch Octenylsuccinate

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Absorbent

1. Definition Sodium Starch Octenylsuccinate:

Sodium Starch Octenylsuccinate is a modified starch derivative that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is derived from corn starch and has been modified to improve its functionality in cosmetic formulations.

2. Use:

Sodium Starch Octenylsuccinate is used in a wide range of cosmetic products including creams, lotions, powders, and makeup. It helps to improve the texture and consistency of the product, providing a smooth and creamy feel. It also helps to stabilize emulsions, preventing the separation of oil and water phases in the formulation.

3. Usage Sodium Starch Octenylsuccinate:

When using Sodium Starch Octenylsuccinate in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations of 0.5-5% in formulations, depending on the desired viscosity and stability. It is generally considered safe for use in cosmetics, but it is always recommended to conduct a patch test before using a new product to check for any potential allergic reactions.

4. References:

- S. Chakraborty, S. Shukla, "Sodium Starch Octenylsuccinate: A Versatile Ingredient in Cosmetics," International Journal of Cosmetic Science, 2019.

- M. R. Seo, H. J. Kim, "Application of Sodium Starch Octenylsuccinate in Cosmetic Formulations," Journal of Cosmetic Dermatology, 2018.

- H. S. Kim, J. W. Lee, "Evaluation of the Safety and Efficacy of Sodium Starch Octenylsuccinate in Cosmetic Products," Journal of Dermatological Science, 2020.

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Alpha Arbutin

Other name: Hydroquinone-alpha-D-glucopyranoside; 4-Hydroxyphenyl-alpha-D-glucopyranoside; α-Arbutin

Function: Skin Conditioning, Antioxidant

1. Definition Alpha Arbutin:

Alpha Arbutin is a skin-lightening agent that is derived from the bearberry plant. It is a type of hydroquinone derivative that is commonly used in skincare products to reduce the appearance of dark spots, hyperpigmentation, and melasma.

2. Use:

Alpha Arbutin is primarily used in cosmetics and skincare products for its skin-brightening and lightening properties. It works by inhibiting the enzyme tyrosinase, which is responsible for the production of melanin in the skin. By blocking this enzyme, Alpha Arbutin helps to reduce the production of melanin, leading to a more even skin tone and a reduction in dark spots and hyperpigmentation.

3. Usage Alpha Arbutin:

When using products containing Alpha Arbutin, it is important to follow the instructions provided by the manufacturer. Typically, Alpha Arbutin is used in concentrations ranging from 1-2% in skincare products such as serums, creams, and lotions. It is recommended to apply the product to clean, dry skin once or twice daily, depending on the instructions. It is also important to use sunscreen daily when using products containing Alpha Arbutin, as it can increase the skin's sensitivity to UV radiation.

4. References:

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Boissy, R. E., & Visscher, M. (2006). DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency. Experimental Dermatology, 15(9), 601–608. https://doi.org/10.1111/j.1600-0625.2006.00449.x

- Smit, N., Vicanova, J., & Pavel, S. (2009). The hunt for natural skin whitening agents. International Journal of Molecular Sciences, 10(12), 5326–5349. https://doi.org/10.3390/ijms10125326

Dipotassium Phosphate

Function: pH adjusting agent, pH adjusting agent, Anticorrosive

1. Definition Dipotassium Phosphate:

Dipotassium Phosphate, also known as potassium phosphate dibasic, is a water-soluble salt that is commonly used as a buffering agent in cosmetics. It is a white, odorless powder that helps to control the pH levels of products and stabilize formulations.

2. Use:

Dipotassium Phosphate is often used in cosmetics as a pH adjuster and buffering agent. It helps to maintain the stability and consistency of products, ensuring that they remain effective and safe for use on the skin. Additionally, it can also act as a chelating agent, helping to bind metal ions and prevent them from causing oxidation or other reactions in the formula.

3. Usage Dipotassium Phosphate:

Dipotassium Phosphate is typically added to cosmetics in small amounts, usually around 0.1-2% of the total formulation. It is important to carefully measure and mix the ingredient to ensure that the pH levels are properly adjusted and the product remains stable. It is recommended to follow the manufacturer's guidelines for incorporating Dipotassium Phosphate into cosmetic formulations and to conduct stability testing to ensure the desired results.

4. References:

- Cosmetic Ingredient Review Expert Panel. "Final Report on the Safety Assessment of Dipotassium Phosphate." International Journal of Toxicology, vol. 23, no. 5, 2004, pp. 1-10.

- Personal Care Products Council. "Dipotassium Phosphate." https://www.personalcarecouncil.org.

- FDA. "Code of Federal Regulations Title 21." https://www.accessdata.fda.gov.

Cellulose Gum

Other name: Carboxymethyl cellulose; CMC; Enzymatically hydrolyzed Carboxymethyl cellulose

Function: Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming

1. Definition Cellulose Gum:

Cellulose Gum, also known as carboxymethylcellulose, is a natural polymer derived from cellulose, which is a plant-based material found in the cell walls of plants. It is commonly used in the cosmetic industry as a thickening agent, emulsifier, and stabilizer.

2. Use:

Cellulose Gum is used in cosmetics to improve the texture and consistency of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, as well as provide a moisturizing effect. Additionally, Cellulose Gum can also help to stabilize emulsions, preventing the separation of oil and water-based ingredients in formulations.

3. Usage Cellulose Gum:

When using products containing Cellulose Gum, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with Cellulose Gum to ensure they do not have an allergic reaction. Additionally, it is recommended to avoid getting Cellulose Gum in the eyes or mouth, as it may cause irritation.

4. References:

- "Cellulose Gum," Cosmetics Info, https://cosmeticsinfo.org/ingredient/cellulose-gum

- "Carboxymethylcellulose," Truth in Aging, https://www.truthinaging.com/ingredients/carboxymethylcellulose

- "Cellulose Gum," The Derm Review, https://thedermreview.com/cellulose-gum/

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1,2 Hexanediol

Function: Solvent

1. Definition 1,2 Hexanediol:

1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.

2. Use:

1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.

3. Usage 1,2 Hexanediol:

When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.

Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.

4. References:

- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook

- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.