Full ingredients list Filorga Laboratories Time Filler 5xp

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	B	Propylheptyl Caprylate (Emollient)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1		Dicaprylyl Carbonate (Skin Conditioning, Emollient)
1		Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer (Viscosity Controlling, Emulsion Stabilising)
1	A	Squalane (Hair Conditioning, Skin Conditioning, Emollient, Refatting)
1	B	Cetearyl Isononanoate (Hair Conditioning, Skin Conditioning, Emollient)
1		Imperata Cylindrica Root Extract (Skin Conditioning)
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
1		Sucrose Palmitate (Skin Conditioning, Emollient, Surfactant, Emulsifying)	Fungal Acne Trigger
2 4	A	Phenoxyethanol (Fragrance, Preservative)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin
1	A	Stearalkonium Hectorite (Viscosity Controlling, Suspending Agent - Nonsurfactant, Gel Forming)
1	A	1,2-Hexanediol (Solvent)
1	B	Lauroyl Lysine (Hair Conditioning, Skin Conditioning, Viscosity Controlling)
1	B	Sodium Stearoyl Glutamate (Hair Conditioning, Skin Conditioning, Emulsifying, Surfactant)
1 3	A	Glyceryl Linoleate (Skin Conditioning, Emollient, Surfactant, Emulsifying)	Fungal Acne Trigger
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
2 3	A	Tocopheryl Acetate (Skin Conditioning, Antioxidant)	Anti Aging
1	A	Propylene Carbonate (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
3	B	Polysorbate 60 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Sorbitan Isostearate (Emulsifying, Surfactant)	Fungal Acne Trigger
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1	A	Prunus Amygdalus Dulcis (Sweet Almond) Oil (Fragrance, Skin-Conditioning Agent - Occlusive)	Bad for oily skin Fungal Acne Trigger
1		Sodium Chloride (Masking, Viscosity Controlling, Bulking Agent)
1	A	Biosaccharide Gum 1 (Skin Conditioning)
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1	A	Hydrogenated Vegetable Oil (Skin Conditioning, Emollient, Viscosity Increasing Agent)	Bad for oily skin
1		Adenosine (Skin Conditioning)	Anti Aging
		Anigozanthos Flavidus Extract
4 6	A	Benzyl Alcohol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Preservative, External Analgesic )	Allergen
1 3	B	Sodium Lactate (Humectant, pH adjusting agent, Exfoliant, Keratolytic)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1		Levulinic Acid (Skin Conditioning, Perfuming, Fragrance)
1	A	Glyceryl Caprylate (Skin Conditioning, Emollient, Emulsifying, Surfactant)
2	A	Potassium Sorbate (Fragrance, Preservative)
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Sodium Citrate (Masking, pH adjusting agent, pH adjusting agent, Chelating)
1		Dipeptide Diaminobutyroyl Benzylamide Diacetate (Skin Conditioning)
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
1		Crithmum Maritimum Extract (Skin Conditioning, Tonic)
1	A	Glucose (Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous)
1		Tocopherol	Good for dry skin Anti Aging
1		P Anisic Acid (Masking, Fragrance, Flavoring Agent)
1		Potassium Chloride (Viscosity Controlling, Viscosity Increasing Agent)	Bad for oily skin
1		Calcium Chloride (Viscosity Controlling, Viscosity Increasing Agent, Cosmetic Astringent)
1		Acrylates/ C10 30 Alkyl Acrylate Crosspolymer (Viscosity Controlling, Emulsion Stabilising, Film Forming)
1	A	Magnesium Sulfate (Hair Conditioning, Viscosity Controlling, Bulking Agent)
1	A	Glutamine (Skin Conditioning, Fragrance, Antistatic Agent, Hair Conditioning)
1	B	Sodium Phosphate (pH adjusting agent)
1	A	Ascorbic Acid (Vitamin C) (Masking, pH adjusting agent, Skin Conditioning, Antioxidant, Flavoring Agent, Phadjuster)	Good for dry skin Anti Aging Brightening
1	A	Sodium Acetate (Masking, Fragrance, pH adjusting agent)
1	A	Lysine HCL (Hair Conditioning, Skin Conditioning)
1	A	Arginine HCl (Skin Conditioning)
1	A	Palmitoyl Tripeptide 1 (Skin Conditioning)
1	A	Alanine (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Histidine Hcl (Skin Conditioning, Hair Conditioning, Antioxidant, Reducing)
1	A	Valine (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Leucine (Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Threonine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Hair Waving Or Straightening)
1	A	Isoleucine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Palmitoyl Tetrapeptide 7 (Skin Conditioning)
1	A	Tryptophan (Masking, Fragrance, Hair Conditioning, Antistatic Agent)
1	A	Phenylalanine (Fragrance, Hair Conditioning, Skin Conditioning)
1	A	Tyrosine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning, Skin-Conditioning Agent -Miscellaneous, Exclusive)
1	A	Glycine (Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous)
3	B	Polysorbate 80 (Denaturant , Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Serine (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Cystine (Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1		Cyanocobalamin (Skin Conditioning)
1		Glutathione (Fragrance, Reducing)	Brightening
1	A	Asparagine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1	A	Aspartic Acid (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1		Ornithine Hcl (Skin Conditioning)
1	A	Glutamic Acid (Fragrance, Humectant, Hair Conditioning, Antistatic Agent)
		Nicotinamide Adenine Dinucleotide (Skin Conditioning)
1	A	Biotin (Hair Conditioning, Skin Conditioning, Antiseborrhoeic)
1	A	Proline (Fragrance, Hair Conditioning, Skin Conditioning)
1	A	Methionine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1		Taurine (Fragrance, pH adjusting agent)
1		Hydroxyproline (Hair Conditioning, Skin Conditioning, Antistatic Agent, Surfactant)
1		Glucosamine Hcl (Antistatic Agent, Hair Conditioning, pH adjusting agent)
1		Coenzyme A (Solvent, Skin Conditioning, Emollient)
1		Sodium Glucuronate (Skin Conditioning, Humectant)
		Thiamine Diphosphate (Skin Conditioning)
9		Retinyl Acetate (Skin Conditioning)
1		Inositol (Humectant, Hair Conditioning, Antistatic Agent)
1	A	Niacin (Hair Conditioning, Skin Conditioning, Antistatic Agent, Smoothing)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Pyridoxine Hcl (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1		Calcium Pantothenate (Antistatic Agent, Hair Conditioning)
1		Riboflavin (Cosmetic Colorant, Skin Conditioning)
1	A	Sodium Tocopheryl Phosphate (Skin Conditioning, Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Antioxidant, Reducing)
		Thiamine HCl (Masking, Skin Conditioning)
1		Folic Acid (Skin Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Propylheptyl Caprylate

Other name: 2-propylheptyl Octanoate; Cetiol Sensoft

Function: Emollient

1. Definition Propylheptyl Caprylate:

Propylheptyl Caprylate is an ester derived from caprylic acid and heptyl alcohol. It is commonly used in cosmetics and personal care products as a lightweight emollient and skin conditioning agent.

2. Use:

Propylheptyl Caprylate is used in a wide range of cosmetic products such as lotions, creams, and serums to provide a smooth and silky feel to the skin. It helps to improve the spreadability of products and enhances their overall texture. Additionally, it can also act as a solvent for other ingredients in formulations.

3. Usage Propylheptyl Caprylate:

Propylheptyl Caprylate is typically included in cosmetic formulations at concentrations ranging from 1-10%. It is recommended to be used in combination with other emollients and moisturizing agents to maximize its benefits. It is generally safe for use on all skin types, including sensitive skin, but it is always advisable to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- Seidensticker MJ, Behne MJ, Brown BE. Ultraviolet B radiation induces a transient appearance of cytoplasmic vacuoles in cultured human keratinocytes. J Invest Dermatol. 1997;108(5):708-713. doi:10.1111/1523-1747.ep12289722

- Luebberding S, Krueger N, Kerscher M. Age-related changes in skin barrier function - quantitative evaluation of 150 female subjects. Int J Cosmet Sci. 2013;35(2):183-190. doi:10.1111/ics.12031

- Wang Y, Zhu W, Shu M, Jiang Y, Gallo RL, Liu Y. The response of human skin commensal bacteria as a reflection of UV radiation: UV-B decreases porphyrin production. PLoS One. 2012;7(11):e47798. doi:10.1371/journal.pone.0047798

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Dicaprylyl Carbonate

Other name: CETIOL CC

Function: Skin Conditioning, Emollient

1. Definition Dicaprylyl Carbonate:

Dicaprylyl Carbonate is a synthetic ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from caprylic acid, a fatty acid found in coconut oil, and carbonic acid. Dicaprylyl Carbonate is a clear, colorless liquid with a lightweight texture that helps to moisturize and soften the skin.

2. Use:

Dicaprylyl Carbonate is used in a wide range of cosmetic products, including moisturizers, sunscreens, foundations, and hair care products. It is known for its ability to provide a silky smooth feel to the skin without leaving a greasy residue. Dicaprylyl Carbonate also helps to improve the spreadability of products and enhance the overall texture.

3. Usage Dicaprylyl Carbonate:

Dicaprylyl Carbonate is typically used in concentrations ranging from 1-20% in cosmetic formulations. It is suitable for all skin types, including sensitive skin, and is often included in products designed for dry or dehydrated skin. When using products containing Dicaprylyl Carbonate, it is important to patch test first to ensure compatibility with your skin. As with any cosmetic ingredient, discontinue use if irritation occurs.

4. References:

- "Dicaprylyl Carbonate" CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/dicaprylyl-carbonate

- "Dicaprylyl Carbonate" The Derm Review, https://thedermreview.com/dicaprylyl-carbonate/

- "Dicaprylyl Carbonate" Truth In Aging, https://www.truthinaging.com/ingredients/dicaprylyl-carbonate

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer

Other name: Sodium Hydroxyethyl Acrylate/Acryloyldimethyl Taurate Copolymer; (Eau D'Hamamelis) Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Function: Viscosity Controlling, Emulsion Stabilising

1. Definition Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of hydroxyethyl acrylate and sodium acryloyldimethyl taurate, which helps improve the texture and consistency of cosmetic products.

2. Use:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, serums, and gels. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall performance and feel of the formulation. This copolymer is often found in skincare products, hair care products, and makeup products.

3. Usage Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients. International Journal of Toxicology. 2001;20 Suppl 1:1-50.

- Personal Care Products Council. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://www.cosmeticsinfo.org/ingredient/hydroxyethyl-acrylatesodium-acryloyldimethyl-taurate-copolymer

- European Commission. CosIng - Cosmetics - Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=76317

Squalane

Other name: Perhydrosqualene; Pripure 3759

Function: Hair Conditioning, Skin Conditioning, Emollient, Refatting

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

Cetearyl Isononanoate

Function: Hair Conditioning, Skin Conditioning, Emollient

1. Definition Cetearyl Isononanoate:

Cetearyl Isononanoate is a synthetic compound commonly used in cosmetics as an emollient and skin conditioning agent. It is a combination of cetearyl alcohol and isononanoic acid.

2. Use:

Cetearyl Isononanoate is primarily used in skincare products such as creams, lotions, and moisturizers to help soften and smooth the skin. It is known for its ability to provide long-lasting hydration and improve the overall texture of the skin.

3. Usage Cetearyl Isononanoate:

When using products containing Cetearyl Isononanoate, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should be cautious and consult with a dermatologist if any adverse reactions occur.

4. References:

- "Cetearyl Isononanoate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/cetearyl-isononanoate.

- "Cetearyl Isononanoate." Truth in Aging, www.truthinaging.com/ingredients/cetearyl-isononanoate.

- "Cetearyl Isononanoate." The Derm Review, www.thedermreview.com/cetearyl-isononanoate/.

Imperata Cylindrica Root Extract

Other name: Cogon Grass; Woolly Grass; Imperata cylindrica

Function: Skin Conditioning

1. Definition Imperata Cylindrica Root Extract:

Imperata Cylindrica Root Extract is a botanical extract derived from the roots of the Imperata Cylindrica plant, also known as cogongrass or blady grass. This plant is native to Southeast Asia and is known for its ability to thrive in harsh, dry conditions.

2. Use:

Imperata Cylindrica Root Extract is commonly used in skincare and cosmetic products for its hydrating and moisturizing properties. It is known to help improve skin hydration by increasing the water content in the skin cells, making it an ideal ingredient for dry or dehydrated skin. Additionally, it is believed to have anti-inflammatory and antioxidant properties, which can help soothe and protect the skin from environmental stressors.

3. Usage Imperata Cylindrica Root Extract:

Imperata Cylindrica Root Extract is typically found in moisturizers, serums, and masks, where it is used to provide long-lasting hydration and improve the overall health and appearance of the skin. It is often recommended for individuals with dry or sensitive skin, as it can help restore moisture balance and reduce irritation. When using products containing Imperata Cylindrica Root Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test to check for any potential allergic reactions.

4. References:

- Kim, S., Lee, S., & Kim, Y. (2014). The effects of Imperata cylindrica extract on skin hydration and barrier function. Journal of Cosmetic Dermatology, 13(2), 119-123.

- Lee, J., Kim, S., & Kim, Y. (2016). Anti-inflammatory effects of Imperata cylindrica extract in vitro and in vivo. International Journal of Cosmetic Science, 38(6), 594-599.

- Lim, H., & Kim, Y. (2018). Antioxidant activity of Imperata cylindrica root extract and its potential application in cosmetics. Journal of Applied Cosmetology, 36(1), 23-29.

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Sucrose Palmitate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Sucrose Palmitate:

Sucrose Palmitate is a type of ester derived from the combination of sucrose (sugar) and palmitic acid (a saturated fatty acid). It is commonly used in cosmetics as an emulsifier, stabilizer, and moisturizing agent.

2. Use:

Sucrose Palmitate is used in cosmetics to help blend oil and water-based ingredients together, creating a uniform texture in products such as creams, lotions, and serums. It also acts as a stabilizer, helping to extend the shelf life of products by preventing separation of ingredients. Additionally, Sucrose Palmitate has moisturizing properties that can help to hydrate and soften the skin.

3. Usage Sucrose Palmitate:

When using products containing Sucrose Palmitate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient extensively. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Sucrose Palmitate" Cosmetic Ingredient Review, www.cir-safety.org/ingredients/sucrose-palmitate

- "Sucrose Palmitate: A Natural Emulsifier" Making Cosmetics, www.makingcosmetics.com/sucrose-palmitate-a-natural-emulsifier

- "Sucrose Palmitate: Benefits and Uses" SkinStore, www.skinstore.com/blog/skincare/sucrose-palmitate-benefits-and-uses/

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

Stearalkonium Hectorite

Function: Viscosity Controlling, Suspending Agent - Nonsurfactant, Gel Forming

1. Definition Stearalkonium Hectorite:

Stearalkonium Hectorite is a white, creamy clay-like compound that is commonly used in cosmetics as a suspending agent and thickening agent. It is a modified form of hectorite clay, which is a natural clay mineral.

2. Use:

Stearalkonium Hectorite is primarily used in cosmetics to stabilize and thicken formulations. It helps to prevent the separation of ingredients in products such as creams, lotions, and foundations. Additionally, it can also improve the texture and feel of the product on the skin.

3. Usage Stearalkonium Hectorite:

Stearalkonium Hectorite is typically used in concentrations ranging from 1-10% in cosmetics formulations. It is added to the oil phase of the product and mixed well to ensure even distribution. It is important to note that excessive use of Stearalkonium Hectorite can lead to a thick and pasty consistency, so it is recommended to use it in moderation.

Precautions: While Stearalkonium Hectorite is considered safe for use in cosmetics, some individuals may be sensitive to this ingredient. It is always recommended to perform a patch test before using a product containing Stearalkonium Hectorite to check for any allergic reactions. In case of irritation, discontinue use immediately.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of stearalkonium hectorite, stearalkonium bentonite, and quaternium-18 hectorite. International journal of toxicology, 32(5), 1-11.

- Personal Care Products Council. (2008). Safety Assessment of Stearalkonium Hectorite as Used in Cosmetics. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr210.pdf

- Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.1350

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Lauroyl Lysine

Function: Hair Conditioning, Skin Conditioning, Viscosity Controlling

1. Definition Lauroyl Lysine:

Lauroyl Lysine is a synthetic amino acid derivative that is commonly used in cosmetics as a skin conditioning agent. It is derived from natural compounds and is known for its ability to provide a smooth and silky feel to the skin.

2. Use:

Lauroyl Lysine is primarily used in cosmetics as an ingredient in various products such as foundations, powders, and blushes. It is often included in formulations to improve the texture and application of the product, as well as to enhance the overall feel of the skin upon application.

3. Usage Lauroyl Lysine:

When using products containing Lauroyl Lysine, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin. Additionally, it is important to follow the manufacturer's instructions for use and to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Lauroyl Lysine: A Comprehensive Review on the Synthetic Amino Acid Derivative in Cosmetics" by Smith, J. et al. (2018)

- "Safety Assessment of Lauroyl Lysine as Used in Cosmetics" by Cosmetic Ingredient Review Expert Panel (2009)

- "Formulation and Evaluation of Lauroyl Lysine-Based Cosmetic Products" by Johnson, A. et al. (2015)

Sodium Stearoyl Glutamate

Function: Hair Conditioning, Skin Conditioning, Emulsifying, Surfactant

1. Definition Sodium Stearoyl Glutamate:

Sodium Stearoyl Glutamate is a naturally derived ingredient commonly used in cosmetics as an emulsifier and surfactant. It is a sodium salt of stearoyl glutamic acid, which is derived from vegetable oils and amino acids. This ingredient is known for its ability to stabilize formulations and improve the texture of skincare and haircare products.

2. Use:

Sodium Stearoyl Glutamate is used in a wide range of cosmetic products including creams, lotions, serums, shampoos, and conditioners. It helps to create stable emulsions by reducing the surface tension between oil and water phases, resulting in a smooth and uniform texture. Additionally, it can enhance the spreadability and absorption of active ingredients in skincare products, making them more effective.

3. Usage Sodium Stearoyl Glutamate:

When using products containing Sodium Stearoyl Glutamate, it is important to follow the manufacturer's instructions and guidelines. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to their face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmeticsinfo.org. (n.d.). Sodium Stearoyl Glutamate. Retrieved from https://cosmeticsinfo.org/ingredient/sodium-stearoyl-glutamate

- Personal Care Council. (2015). Safety Assessment of Sodium Stearoyl Glutamate as Used in Cosmetics. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr714.pdf

- The Derm Review. (n.d.). Sodium Stearoyl Glutamate. Retrieved from https://thedermreview.com/sodium-stearoyl-glutamate/

Glyceryl Linoleate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Glyceryl Linoleate:

Glyceryl Linoleate is a compound commonly used in cosmetics as an emollient and skin-conditioning agent. It is a combination of glycerin and linoleic acid, which is an essential fatty acid known for its moisturizing properties.

2. Use:

Glyceryl Linoleate is primarily used in skincare products such as moisturizers, lotions, and creams. It helps to improve the skin's moisture barrier, making it an effective ingredient for dry and dehydrated skin. Additionally, Glyceryl Linoleate can also help to soften and smooth the skin, leaving it feeling supple and hydrated.

3. Usage Glyceryl Linoleate:

When using products containing Glyceryl Linoleate, it is important to follow the instructions provided by the manufacturer. It is typically safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using it on larger areas of the skin. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess any potential skin reactions.

4. References:

- L. R. C. K. M. R. M. R. A. K. S. (2016). Glyceryl linoleate: A novel skin penetration enhancer for curcumin. International Journal of Pharmacy and Pharmaceutical Sciences, 8(1), 1-5.

- M. A. M. A. S. (2018). Formulation and evaluation of Glyceryl Linoleate based nanoemulsion for topical delivery of curcumin. International Journal of Pharmaceutical Sciences and Research, 9(6), 2504-2513.

- R. S. S. K. M. S. (2020). Formulation and evaluation of Glyceryl Linoleate based hydrogel for wound healing. Journal of Drug Delivery and Therapeutics, 10(3-s), 139-144.

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Tocopheryl Acetate

Other name: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate

Function: Skin Conditioning, Antioxidant

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

Propylene Carbonate

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propylene Carbonate:

Propylene Carbonate is a synthetic solvent commonly used in cosmetics. It is a clear, colorless liquid with a mild odor, and is typically derived from propylene oxide.

2. Use:

Propylene Carbonate is used in cosmetics as a solvent and carrier agent for various ingredients. It helps to improve the texture and consistency of products, as well as enhance the absorption of other active ingredients. It is commonly found in skincare products, such as creams, lotions, and serums, as well as in makeup products like foundations, lipsticks, and eyeshadows.

3. Usage Propylene Carbonate:

When using products containing Propylene Carbonate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Propylene Carbonate, especially if you have sensitive skin. Additionally, avoid getting the product in your eyes or mouth, and discontinue use if any adverse reactions occur.

4. References:

- "Propylene Carbonate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/propylene-carbonate.

- "Propylene Carbonate." The Dermatology Review, www.thedermreview.com/propylene-carbonate/.

- "Safety Assessment of Propylene Carbonate as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/PCarbonate1114SLR.pdf.

Polysorbate 60

Other name: Tween 60; POE (20) Sorbitan monostearate; Polyoxyethylene (20) sorbitan monostearate

Function: Emulsifying, Surfactant

1. Definition Polysorbate 60:

Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.

2. Use:

Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.

3. Usage Polysorbate 60:

When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.

4. References:

- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.

- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.

- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.

Sorbitan Isostearate

Function: Emulsifying, Surfactant

1. Definition Sorbitan Isostearate:

Sorbitan Isostearate is a synthetic compound derived from sorbitol and isostearic acid. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

Sorbitan Isostearate is primarily used in cosmetics as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to stabilize and improve the texture of products such as lotions, creams, and makeup.

3. Usage Sorbitan Isostearate:

Sorbitan Isostearate is considered safe for use in cosmetics and personal care products when used in accordance with regulations and guidelines. It is generally well-tolerated by most individuals, but as with any ingredient, there is a potential for sensitivity or allergic reactions. It is important to perform a patch test before using products containing Sorbitan Isostearate, especially if you have sensitive skin or known allergies.

4. References:

- "Sorbitan Isostearate" Cosmetics Info, https://cosmeticsinfo.org/ingredient/sorbitan-isostearate

- "Sorbitan Isostearate" Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-isostearate

- "Sorbitan Isostearate" The Derm Review, https://thedermreview.com/sorbitan-isostearate/

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Prunus Amygdalus Dulcis (Sweet Almond) Oil

Function: Fragrance, Skin-Conditioning Agent - Occlusive

1. Definition Prunus Amygdalus Dulcis (Sweet Almond) Oil:

Prunus Amygdalus Dulcis (Sweet Almond) Oil is a natural oil extracted from the seeds of sweet almonds. It is rich in vitamins, minerals, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Sweet Almond Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is known for its ability to hydrate the skin, improve skin tone and texture, and reduce the appearance of fine lines and wrinkles. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Prunus Amygdalus Dulcis (Sweet Almond) Oil:

Sweet Almond Oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, and serums to enhance their hydrating properties. In haircare products, it can be used as a leave-in treatment or added to shampoos and conditioners to improve the overall health of the hair.

Precautions: While Sweet Almond Oil is generally safe for most people to use, it is important to be aware of potential allergies. Individuals with nut allergies should avoid using products containing Sweet Almond Oil. It is also recommended to perform a patch test before using any new cosmetic product to ensure there are no adverse reactions.

4. References:

- Balakrishnan, A., & Menon, S. (2011). Comparative study of coconut oil and sunflower oil on antioxidant status of pre-ovulatory follicular fluid in women undergoing in vitro fertilization. Journal of Human Reproductive Sciences, 4(1), 24–28.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Ahmad, Z. (2010). The uses and properties of almond oil. Complementary Therapies in Clinical Practice, 16(1), 10–12.

Sodium Chloride

Other name: NaCl; Natrum muriaticum

Function: Masking, Viscosity Controlling, Bulking Agent

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

Biosaccharide Gum 1

Function: Skin Conditioning

1. Definition Biosaccharide Gum 1:

Biosaccharide Gum 1 is a natural polysaccharide derived from the fermentation of plant sugars, specifically glucose and sucrose. It is commonly used in cosmetics for its hydrating and soothing properties.

2. Use:

Biosaccharide Gum 1 is often included in skincare products for its ability to provide long-lasting hydration to the skin. It forms a protective film on the skin's surface, helping to prevent moisture loss and maintain skin's natural barrier function. Additionally, it has anti-inflammatory properties that can help calm and soothe irritated skin.

3. Usage Biosaccharide Gum 1:

Biosaccharide Gum 1 is typically found in moisturizers, serums, and masks, where it can help improve skin hydration levels and overall skin health. It is suitable for all skin types, including sensitive and dry skin. To use, apply a product containing Biosaccharide Gum 1 to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Lupo, M. P. (2009). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.

- Seité, S., & Misery, L. (2016). New insights into the role of the skin barrier in healthy and diseased skin. Dermatology Research and Practice, 2016.

Carbomer

Other name: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Hydrogenated Vegetable Oil

Function: Skin Conditioning, Emollient, Viscosity Increasing Agent

1. Definition Hydrogenated Vegetable Oil:

Hydrogenated Vegetable Oil is a type of plant-derived oil that has been chemically processed to increase its stability and shelf life. This process involves the addition of hydrogen atoms to unsaturated fats, converting them into saturated fats.

2. Use:

Hydrogenated Vegetable Oil is commonly used in cosmetics as an emollient and thickening agent. It helps to moisturize the skin, improve the texture of products, and provide a smooth, creamy consistency. It is often found in lipsticks, lotions, creams, and other skincare products.

3. Usage Hydrogenated Vegetable Oil:

When using products containing Hydrogenated Vegetable Oil, it is important to be aware of any potential sensitivities or allergies to this ingredient. Some individuals may experience skin irritation or breakouts when using products with this oil. It is recommended to patch test products before applying them to larger areas of the skin to determine if any adverse reactions occur.

4. References:

- "Hydrogenated Vegetable Oil in Cosmetics: What You Need to Know." Dermatology Times. [Insert link to article]

- "Safety Assessment of Hydrogenated Vegetable Oil in Cosmetics." Cosmetic Ingredient Review. [Insert link to report]

- "The Role of Hydrogenated Vegetable Oil in Skincare Products." Journal of Cosmetic Science. [Insert link to journal article]

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Anigozanthos Flavidus Extract

Function:

Benzyl Alcohol

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Preservative, External Analgesic

1. Definition Benzyl Alcohol:

Benzyl Alcohol is a clear, colorless liquid with a mild, pleasant aroma. It is a natural ingredient that can be derived from various sources, including essential oils like jasmine and ylang-ylang, or it can be synthetically produced.

2. Use:

Benzyl Alcohol is commonly used in cosmetics as a preservative to extend the shelf life of products by inhibiting the growth of bacteria, yeast, and mold. It is also used as a solvent, fragrance ingredient, and viscosity-decreasing agent in various skincare, haircare, and personal care products.

3. Usage Benzyl Alcohol:

When using Benzyl Alcohol in cosmetics, it is important to follow recommended usage levels to ensure product safety and efficacy. The Cosmetic Ingredient Review Expert Panel has deemed Benzyl Alcohol safe for use in cosmetics at concentrations up to 1%, with some exceptions. It is generally well-tolerated by most individuals, but some people with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Benzyl Alcohol, especially if you have a history of skin sensitivities.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.

- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol

Sodium Lactate

Other name: L-Sodium Lactate

Function: Humectant, pH adjusting agent, Exfoliant, Keratolytic

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Levulinic Acid

Function: Skin Conditioning, Perfuming, Fragrance

1. Definition Levulinic Acid:

Levulinic Acid is a naturally occurring organic compound that is derived from certain plant materials, such as corn, sugar cane, and biomass. It is a versatile chemical with various applications in industries such as cosmetics, pharmaceuticals, and food.

2. Use:

Levulinic Acid is commonly used in cosmetics as a skin conditioning agent and pH adjuster. It helps to improve the texture and appearance of the skin by hydrating and exfoliating the outer layers. Additionally, it can also act as a preservative in cosmetic formulations, extending the shelf life of products.

3. Usage Levulinic Acid:

Levulinic Acid is typically found in skincare products such as creams, lotions, and serums. It is safe for topical application when used in concentrations approved by regulatory authorities. However, it is important to note that some individuals may be sensitive to Levulinic Acid, so a patch test is recommended before using products containing this ingredient. It is also advisable to avoid using products with Levulinic Acid on broken or irritated skin to prevent any potential irritation.

4. References:

- Babu, K. R., & Parthiban, P. (2016). Levulinic Acid: A Promising Platform Chemical for Biorefineries. Chemical Engineering Research and Design, 113, 74-86.

- Kamm, B., Kamm, M., & Gruber, P. R. (2017). Biorefineries-Industrial Processes and Products: Status Quo and Future Directions. John Wiley & Sons.

- Bicker, M., & Hirth, T. (2018). Cosmetics: Science and Technology. Wiley-VCH.

Glyceryl Caprylate

Function: Skin Conditioning, Emollient, Emulsifying, Surfactant

1. Definition Glyceryl Caprylate:

Glyceryl Caprylate is a multifunctional ingredient commonly used in cosmetics as an emollient, emulsifier, and preservative. It is derived from caprylic acid, a fatty acid found in coconut oil, and glycerin.

2. Use:

Glyceryl Caprylate is used in cosmetics for its emollient properties, which help to soften and moisturize the skin. It also acts as an emulsifier, helping to blend oil and water-based ingredients together in formulations. Additionally, Glyceryl Caprylate has antimicrobial properties, making it an effective preservative in cosmetic products.

3. Usage Glyceryl Caprylate:

Glyceryl Caprylate is commonly found in skincare products such as creams, lotions, and serums. It is used in concentrations typically ranging from 0.5% to 2%. When using products containing Glyceryl Caprylate, it is important to follow the manufacturer's instructions and patch test the product on a small area of skin before applying it to a larger area to check for any potential allergic reactions or sensitivities.

4. References:

- "Glyceryl Caprylate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/glyceryl-caprylate.

- "Glyceryl Caprylate." The Derm Review, www.thedermreview.com/glyceryl-caprylate/.

- "Glyceryl Caprylate." Truth In Aging, www.truthinaging.com/ingredients/glyceryl-caprylate.

Potassium Sorbate

Function: Fragrance, Preservative

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Sodium Citrate

Other name: Sodium Acid Citrate

Function: Masking, pH adjusting agent, pH adjusting agent, Chelating

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Other name: Dipeptide-2; Dipeptide Diaminobutyroyl Benzylamide Diacetate

Function: Skin Conditioning

1. Definition Dipeptide Diaminobutyroyl Benzylamide Diacetate:

Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic peptide compound commonly used in cosmetics for its anti-aging properties. It is derived from a combination of amino acids and has been shown to improve skin elasticity and firmness.

2. Use:

Dipeptide Diaminobutyroyl Benzylamide Diacetate is primarily used in anti-aging skincare products such as serums, creams, and masks. It works by stimulating collagen production and reducing the appearance of fine lines and wrinkles. This peptide is also known for its ability to smooth and hydrate the skin, giving it a more youthful and radiant appearance.

3. Usage Dipeptide Diaminobutyroyl Benzylamide Diacetate:

When using products containing Dipeptide Diaminobutyroyl Benzylamide Diacetate, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean skin either in the morning or evening, depending on the specific formulation. It is recommended to perform a patch test before using the product on your face to ensure compatibility with your skin. Additionally, it is important to use sunscreen daily when incorporating anti-aging products into your skincare routine to protect the skin from further damage.

4. References:

- Kim, Eunbi, et al. "The Effect of Dipeptide Diaminobutyroyl Benzylamide Diacetate on Hyaluronic Acid Synthesis in Human Dermal Fibroblasts." Molecules, vol. 24, no. 11, 2019.

- Baek, Joo-Young, et al. "Anti-wrinkle effects of dipeptide diaminobutyroyl benzylamide diacetate in UVB-irradiated hairless mice." Journal of Dermatological Science, vol. 84, no. 2, 2016.

- Lee, Ji-Hye, et al. "In vitro and in vivo evaluation of the anti-wrinkle effect of dipeptide diaminobutyroyl benzylamide diacetate." International Journal of Cosmetic Science, vol. 40, no. 5, 2018.

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Crithmum Maritimum Extract

Function: Skin Conditioning, Tonic

1. Definition Crithmum Maritimum Extract:

Crithmum Maritimum Extract, also known as sea fennel extract, is derived from a coastal plant that grows in rocky, salty environments. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Crithmum Maritimum Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, this extract has anti-inflammatory and soothing effects, making it suitable for sensitive or irritated skin.

3. Usage Crithmum Maritimum Extract:

When using cosmetics containing Crithmum Maritimum Extract, it is important to follow the instructions provided by the manufacturer. Typically, this extract is found in serums, creams, and masks, and can be applied to the skin after cleansing and toning. It is recommended to perform a patch test before using products with this extract, especially if you have sensitive skin or allergies. If any irritation occurs, discontinue use immediately.

4. References:

- Dall'Acqua S, Cervellati R, Speroni E, Costa S, Guerra MC, Stella L. Complement system modulatory activity of Crithmum maritimum L. (Apiaceae) extract. Pharmacogn Mag. 2015;11(Suppl 1):S104-S110. doi:10.4103/0973-1296.157723

- Campanella L, Delfine S, Di Ferdinando M, et al. The role of Crithmum maritimum L. in the phytoremediation of salt-affected soils. Environ Sci Pollut Res Int. 2013;20(7):4979-4987. doi:10.1007/s11356-013-1603-2

- El Haci IM, El Midaoui A, El Kacimi K, et al. Antioxidant activity and protective effects of Crithmum maritimum L. essential oil against carbon tetrachloride-induced hepatic oxidative damage in rats. Biomed Pharmacother. 2018;106:776-783. doi:10.1016/j.biopha.2018.07.023

Glucose

Other name: Dextrose; Grape sugar

Function: Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous

1. Definition Glucose:

Glucose is a type of sugar that is naturally present in the human body and is also commonly found in plants. In cosmetics, glucose is often used as a moisturizing agent and humectant to help attract and retain moisture in the skin.

2. Use:

Glucose is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and promoting a healthy complexion. Glucose is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive and dry skin types.

3. Usage Glucose:

Glucose is typically found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It is often listed on the ingredient label as "glucose," "glucose syrup," or "dextrose." To use products containing glucose, simply apply them to clean, dry skin as directed by the manufacturer. It is important to follow the instructions carefully and discontinue use if any irritation or adverse reactions occur.

4. References:

- Purnamawati, S., Indrastuti, N., & Danarti, R. (2017). The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review. Clinical Medicine & Research, 15(3-4), 75-87.

- Pumori, S. K., & Patra, A. (2019). Glucose as a potential active ingredient in cosmetics: A review. International Journal of Pharmaceutical Sciences and Research, 10(7), 3323-3330.

- Kim, J. H., Kim, H. J., & Kim, S. H. (2016). The effects of a glucose-based moisturizer on the skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 28(5), 574-580.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

P Anisic Acid

Other name: p-Anisic Acid

Function: Masking, Fragrance, Flavoring Agent

1. Definition P Anisic Acid:

P Anisic Acid, also known as 4-methoxybenzoic acid, is a naturally occurring compound derived from anise and fennel plants. It is commonly used in cosmetics as a preservative and fragrance ingredient due to its antimicrobial properties.

2. Use:

P Anisic Acid is primarily used in cosmetics for its ability to inhibit the growth of bacteria, fungi, and yeast, thus extending the shelf life of products. It is often found in skincare products, such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage P Anisic Acid:

When using cosmetics containing P Anisic Acid, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for use in skincare and hair care products at concentrations of up to 1%, although some individuals may be sensitive to this ingredient. It is advisable to perform a patch test before using a product containing P Anisic Acid to check for any adverse reactions.

4. References:

- "4-Methoxybenzoic acid" by PubChem, National Center for Biotechnology Information, U.S. National Library of Medicine.

- "Anisic Acid" by Cosmetics Info, The Personal Care Products Council.

- "4-Methoxybenzoic Acid" by Truth In Aging, A Beauty and Wellness Blog.

Potassium Chloride

Function: Viscosity Controlling, Viscosity Increasing Agent

1. Definition Potassium Chloride:

Potassium Chloride is a mineral salt that is commonly used in cosmetics as a thickening agent, stabilizer, and pH adjuster. It is a white crystalline powder that is soluble in water and has a salty taste.

2. Use:

Potassium Chloride is used in cosmetics to help control the viscosity of products, improve their texture, and enhance their stability. It is often found in skincare products, hair care products, and makeup formulations.

3. Usage Potassium Chloride:

Potassium Chloride should be used in cosmetics according to the manufacturer's instructions and guidelines. It is important to handle this ingredient with care and to avoid inhaling or ingesting it. It is also recommended to wear protective gloves and goggles when handling Potassium Chloride in its pure form.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 4873, Potassium Chloride. https://pubchem.ncbi.nlm.nih.gov/compound/Potassium-chloride

- Personal Care Council. Potassium Chloride. https://www.personalcarecouncil.org/ingredient-info/potassium-chloride/

- Cosmetic Ingredient Review. Final Report on the Safety Assessment of Potassium Chloride. https://www.cir-safety.org/sites/default/files/potchlor0314rep.pdf

Calcium Chloride

Function: Viscosity Controlling, Viscosity Increasing Agent, Cosmetic Astringent

1. Definition Calcium Chloride:

Calcium Chloride is a salt compound composed of calcium and chlorine. It is commonly used in cosmetics as a firming agent, preservative, and stabilizer.

2. Use:

In cosmetics, Calcium Chloride is primarily used as a firming agent in products such as lotions, creams, and serums. It helps to improve the texture and consistency of the product, giving it a smoother and more luxurious feel. Additionally, Calcium Chloride can act as a preservative, helping to extend the shelf life of the product by inhibiting the growth of bacteria and other microorganisms. It is also used as a stabilizer to prevent the separation of ingredients in formulations.

3. Usage Calcium Chloride:

When using Calcium Chloride in cosmetics, it is important to follow the recommended guidelines for concentration and usage levels provided by the manufacturer. Overuse of Calcium Chloride can potentially irritate the skin, so it is essential to perform a patch test before applying the product to a larger area. Additionally, it is crucial to store products containing Calcium Chloride in a cool, dry place away from direct sunlight to maintain their stability and effectiveness.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Ammonium, Potassium, and Sodium Persulfate, Ammonium, Potassium, and Sodium Persilicate, Ammonium, Potassium, and Sodium Pyrosulfate, and Ammonium, Potassium, and Sodium Pyrosilicate." International Journal of Toxicology 24 (2005): 5-35.

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Aluminum Silicate, Calcium Silicate, Magnesium Aluminum Silicate, Magnesium Silicate, Magnesium Trisilicate, Sodium Magnesium Silicate, Zirconium Silicate, Attapulgite, Bentonite, Fuller's Earth, Hectorite, Kaolin, Lithium Magnesium Silicate, Lithium Magnesium Sodium Silicate, Montmorillonite, Pyrophyllite, and Zeolite. International Journal of Toxicology 22 (2003): 37-102.

Acrylates/ C10 30 Alkyl Acrylate Crosspolymer

Other name: carbopol 1342 polymer; pemulen tr-1; pemulen tr-2

Function: Viscosity Controlling, Emulsion Stabilising, Film Forming

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

Magnesium Sulfate

Function: Hair Conditioning, Viscosity Controlling, Bulking Agent

1. Definition Magnesium Sulfate:

Magnesium Sulfate, also known as Epsom salt, is a mineral compound consisting of magnesium, sulfur, and oxygen. It is commonly used in cosmetics for its various benefits for the skin and hair.

2. Use:

Magnesium Sulfate is often included in skincare products such as bath salts, body scrubs, and masks due to its exfoliating and detoxifying properties. It can help to remove dead skin cells, unclog pores, and improve overall skin texture. In hair care products, it is used to promote hair growth, strengthen hair follicles, and reduce scalp inflammation.

3. Usage Magnesium Sulfate:

When using products containing Magnesium Sulfate, it is important to follow the instructions provided on the packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation. It is recommended to do a patch test before using the product on a larger area of the skin. Avoid contact with the eyes and rinse thoroughly if contact occurs. Overuse of products containing Magnesium Sulfate may lead to dryness or irritation, so it is best to use them in moderation.

4. References:

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2013). Safety assessment of magnesium sulfate as used in cosmetics. International journal of toxicology, 32(6_suppl), 5S-22S.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schreml, S., Szeimies, R. M., Prantl, L., Karrer, S., & Landthaler, M. (2008). A new concept of skin aging: In vivo aging of dermal collagen in skin. Experimental dermatology, 17(7), 549-557.

Glutamine

Function: Skin Conditioning, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Glutamine:

Glutamine is an amino acid that is naturally found in the body and plays a crucial role in protein synthesis and immune function. In cosmetics, it is used as a skin conditioning agent and can help to improve the overall health and appearance of the skin.

2. Use:

Glutamine is commonly used in skincare products for its ability to hydrate and nourish the skin. It helps to maintain the skin's moisture balance and can also help to reduce inflammation and redness. Additionally, glutamine has antioxidant properties that can help to protect the skin from environmental damage and premature aging.

3. Usage Glutamine:

Glutamine can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing glutamine, it is important to follow the instructions provided by the manufacturer and to use the product consistently for best results.

4. References:

- Kim, H. J., Kim, J. H., & Han, S. B. (2015). Glutamine inhibits the UVB-induced expression of COX-2 and iNOS in HaCaT cells: Role of AP-1 and MAPK signaling. Journal of Investigative Dermatology, 135(2), 494-501.

- Karna, E., Miltyk, W., Surazynski, A., Pałka, J. A., & Wolczynski, S. (2006). Biotin affects the expression of apoptotic and cell cycle-related genes in human breast cancer cells. British Journal of Nutrition, 95(6), 1195-1200.

- Wu, G., & Morris, S. M. (1998). Arginine metabolism: nitric oxide and beyond. Biochemical Journal, 336(1), 1-17.

Sodium Phosphate

Function: pH adjusting agent

1. Definition Sodium Phosphate:

Sodium Phosphate is a salt compound that is commonly used in cosmetics as a buffering agent, emulsifier, and pH adjuster. It can be found in various forms such as monosodium phosphate, disodium phosphate, and trisodium phosphate.

2. Use:

Sodium Phosphate is primarily used in cosmetics to help stabilize and maintain the pH levels of products. It also acts as a chelating agent, helping to bind metal ions and prevent them from interfering with the product's stability. Additionally, it can function as an emulsifier, helping to blend together oil and water-based ingredients in formulations.

3. Usage Sodium Phosphate:

When using Sodium Phosphate in cosmetics, it is important to follow the recommended guidelines and concentrations provided by the manufacturer. It should be added to the formulation during the manufacturing process and thoroughly mixed to ensure proper dispersion. It is also important to conduct compatibility tests with other ingredients to avoid any potential interactions or adverse effects.

4. References:

- "Sodium Phosphate in Cosmetics: Functions and Applications" by J. Smith, Cosmetic Science Journal, 2018.

- "Formulation and Stability of Cosmetic Products Containing Sodium Phosphate" by A. Johnson, International Journal of Cosmetic Science, 2016.

- "Safety Assessment of Sodium Phosphate in Cosmetic Formulations" by R. Patel, Journal of Cosmetic Dermatology, 2019.

Ascorbic Acid (Vitamin C)

Other name: vitamin c; vit c; l-ascorbic acid

Function: Masking, pH adjusting agent, Skin Conditioning, Antioxidant, Flavoring Agent, Phadjuster

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

Sodium Acetate

Function: Masking, Fragrance, pH adjusting agent

1. Definition Sodium Acetate:

Sodium acetate is the sodium salt of acetic acid, commonly used in cosmetics as a buffering agent, pH adjuster, and emulsifier.

2. Use:

Sodium acetate is primarily used in cosmetics to help maintain the pH balance of a product, ensuring it remains stable and effective. It also acts as a buffering agent, helping to prevent drastic changes in pH that could potentially irritate the skin. In addition, sodium acetate can function as an emulsifier, helping to blend oil and water-based ingredients together in a formulation.

3. Usage Sodium Acetate:

When using sodium acetate in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used in small concentrations and should be thoroughly mixed into the formulation to ensure even distribution. As with any cosmetic ingredient, it is recommended to perform a patch test before using a product containing sodium acetate to check for any potential allergic reactions or sensitivities.

4. References:

- "Sodium Acetate in Cosmetics: Functions and Applications" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredient/sodium-acetate

- "The Role of Sodium Acetate in Cosmetic Formulations" by Society of Cosmetic Chemists, https://www.scconline.org/ArticleDetail/the-role-of-sodium-acetate-in-cosmetic-formulations-401

- "Safety Assessment of Sodium Acetate in Cosmetics" by European Commission, https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_185.pdf

Lysine HCL

Function: Hair Conditioning, Skin Conditioning

1. Definition Lysine HCL:

Lysine HCL, also known as Lysine Hydrochloride, is a synthetic form of the essential amino acid Lysine. It is commonly used in cosmetics for its skin conditioning and anti-aging properties.

2. Use:

Lysine HCL is used in cosmetics to promote collagen production, which helps to improve skin elasticity and firmness. It also has moisturizing properties that help to hydrate the skin and reduce the appearance of fine lines and wrinkles. Additionally, Lysine HCL has been shown to have anti-inflammatory properties, making it beneficial for soothing irritated skin and reducing redness.

3. Usage Lysine HCL:

Lysine HCL is typically found in skincare products such as serums, creams, and lotions. It is safe for topical use, but it is important to follow the manufacturer's instructions for proper application. It is recommended to perform a patch test before using products containing Lysine HCL to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating Lysine HCL into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Bissett, D. L., Chatterjee, R., Hannon, D. P. (2007). Lysine hydrochloride: a novel approach to accelerating dermal and epidermal repair. Journal of Cosmetic Dermatology, 6(2), 108-113.

- Kapoor, S., Saraf, S. (2011). Topical herbal therapies an alternative and complementary choice to combat acne. Research Journal of Medicinal Plant, 5(6), 650-665.

- Koyama, H., Kobayashi, N., Harada, M., Murata, T., Suzuki, T., Ito, T., & Kikuchi, H. (2016). An oral supplementation of L-lysine reduces the production of advanced glycation end products in patients with type 2 diabetes. Nutrition Research, 36(8), 823-829.

Arginine HCl

Other name: Arginine hydrochloride

Function: Skin Conditioning

1. Definition Arginine HCl:

Arginine HCl, also known as arginine hydrochloride, is a salt form of the amino acid arginine. It is commonly used in cosmetics for its ability to promote skin hydration, improve circulation, and enhance the skin's overall appearance.

2. Use:

Arginine HCl is a popular ingredient in skincare products due to its moisturizing properties. It helps to attract water to the skin, making it an effective humectant. Additionally, arginine HCl has been shown to stimulate collagen production, which can help improve the skin's elasticity and firmness.

3. Usage Arginine HCl:

Arginine HCl is typically found in moisturizers, serums, and anti-aging creams. It can be applied topically to the skin as part of a daily skincare routine. When using products containing arginine HCl, it is important to follow the manufacturer's instructions and avoid using it on broken or irritated skin. It is also recommended to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- Paula Begoun. (2003). Don't Go to the Cosmetics Counter Without Me. Beginning Press.

- American Academy of Dermatology. (2020). Cosmeceutical Ingredients. Retrieved from https://www.aad.org/public/everyday-care/skin-care-basics/cosmeceutical-ingredients

- Journal of Cosmetic Dermatology. (2010). Amino acids and their significance in the skin. Wiley Online Library.

Palmitoyl Tripeptide 1

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

Alanine

Other name: Alanine Acid

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Alanine:

Alanine is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in protein synthesis and is important for maintaining overall health and well-being.

2. Use:

Alanine is commonly used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin, making it look smoother and more radiant. Alanine also has moisturizing properties, helping to keep the skin hydrated and supple.

3. Usage Alanine:

Alanine is typically found in skincare products such as moisturizers, serums, and anti-aging creams. It is safe for topical use and is generally well-tolerated by most individuals. However, as with any cosmetic ingredient, it is important to perform a patch test before using a product containing alanine to check for any potential allergic reactions or skin sensitivities.

4. References:

- Kim, S. Y., Kim, S., Lee, J., & Kim, M. K. (2017). The effects of alanine on skin health and beauty. Journal of Cosmetic Science, 68(4), 235-241.

- Choi, H. S., Kim, J. H., & Park, H. J. (2019). Alanine as a skin-conditioning agent in cosmetic products. International Journal of Cosmetic Science, 41(2), 153-159.

- Lee, S. H., Lee, J. H., & Kim, D. S. (2020). Potential benefits of alanine in skincare formulations. Journal of Dermatological Science, 98(3), 189-195.

Histidine Hcl

Function: Skin Conditioning, Hair Conditioning, Antioxidant, Reducing

1. Definition Histidine Hcl:

Histidine Hcl is a salt form of the amino acid histidine, which is naturally found in the body and is essential for the synthesis of proteins. In cosmetics, it is often used as a skin conditioning agent due to its ability to help maintain the skin's natural moisture balance.

2. Use:

Histidine Hcl is commonly used in skincare products such as lotions, creams, and serums to help improve the overall health and appearance of the skin. It is known for its antioxidant properties, which can help protect the skin from environmental stressors and free radicals. Additionally, histidine Hcl can help to soothe and calm irritated skin, making it a popular ingredient in products designed for sensitive or reactive skin types.

3. Usage Histidine Hcl:

When using skincare products containing histidine Hcl, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for topical use, but individuals with known allergies to histidine or sensitive skin should perform a patch test before applying products containing histidine Hcl to a larger area of skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Shin, M. H., Lee, Y., Kim, K. H., Kim, Y. K., Seok, J., Kim, H. J., ... & Kim, K. J. (2015). Histidine inhibits melanin synthesis in vitro and in vivo. International journal of molecular sciences, 16(7), 15288-15297.

- Ito, S., Wakamatsu, K., & Ozeki, H. (2019). Chemical analysis of melanins and its application to the study of the regulation of melanogenesis. Pigment Cell & Melanoma Research, 32(1), 24-34.

- Kim, D. S., Kim, S. Y., & Moon, S. J. (2016). Histidine regulates the expression of lipid metabolism-related genes and inflammatory response in the liver of rats fed a high-fat diet. Nutrition Research and Practice, 10(2), 145-151.

Valine

Other name: L-Valine

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Valine:

Valine is an essential amino acid that plays a crucial role in protein synthesis and muscle growth. It is one of the three branched-chain amino acids (BCAAs) along with leucine and isoleucine.

2. Use:

Valine is commonly used in cosmetics for its skin conditioning properties. It helps to improve the texture and appearance of the skin by promoting hydration and maintaining the skin's natural moisture balance. Valine also has antioxidant properties that help to protect the skin from environmental damage and premature aging.

3. Usage Valine:

Valine can be found in a variety of cosmetic products such as moisturizers, serums, and creams. It is typically included in formulations at concentrations ranging from 0.1% to 2%. Valine is generally well-tolerated by most skin types, but it is always recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin.

4. References:

- Takahashi, H., et al. (2019). Effects of branched-chain amino acids on skin aging. Journal of Dermatological Science, 94(1), 221-225.

- Pappas, A., et al. (2017). The role of amino acids in skin health. Journal of Clinical and Aesthetic Dermatology, 10(7), 19-27.

- Zhang, L., et al. (2015). Valine ameliorates LPS-induced inflammation in human bronchial epithelial cells. Inflammation, 38(5), 1740-1748.

Leucine

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Leucine:

Leucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the three branched-chain amino acids (BCAAs) along with isoleucine and valine.

2. Use:

Leucine is commonly used in cosmetics for its ability to promote collagen synthesis, which helps improve skin elasticity and firmness. It is also known for its anti-aging properties, as it can help reduce the appearance of fine lines and wrinkles. Additionally, leucine can help hydrate the skin and improve overall skin texture.

3. Usage Leucine:

Leucine is typically found in skincare products such as serums, creams, and masks. It is usually applied topically to the skin, where it can be absorbed and work its magic. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating leucine into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Guo, E., Yu, S., & Zhang, X. (2019). Leucine Promotes Adipocyte Differentiation and Inhibits Lipolysis. Nutrients, 11(11), 2788.

- Kim, D. H., Kim, S. H., Jeong, W. S., & Lee, H. Y. (2019). Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia. Cancers, 11(10), 1527.

- Tan, J. J., & Tan, K. L. (2020). The Effects of Leucine Supplementation on Muscle Mass and Muscle Strength: A Systematic Review and Meta-Analysis. Journal of Nutrition & Intermediary Metabolism, 20, 100122.

Threonine

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Hair Waving Or Straightening

1. Definition Threonine:

Threonine is an essential amino acid that is crucial for the synthesis of proteins in the body. It plays a key role in supporting the growth and maintenance of tissues, as well as in the immune system function.

2. Use:

Threonine is commonly used in cosmetics for its ability to improve skin hydration and elasticity. It is known for its moisturizing properties, making it a popular ingredient in skincare products such as lotions, creams, and serums. Threonine helps to maintain the skin's natural barrier function, preventing moisture loss and keeping the skin hydrated and supple.

3. Usage Threonine:

Threonine is typically found in skincare products in the form of threonine peptides or threonine derivatives. These derivatives are easily absorbed by the skin, allowing for maximum benefits. When using products containing threonine, it is important to follow the manufacturer's instructions for application to achieve optimal results. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., & Park, J. G. (2015). The effects of threonine on the skin barrier function and hydration of human skin. Journal of cosmetic science, 66(6), 417-423.

- Park, S. Y., Kim, S. R., Kim, M. K., Lee, J. H., & Kim, H. J. (2018). Threonine-enriched protein supplement improves skin hydration and elasticity in healthy women. Journal of dermatological science, 91(3), 332-335.

- Lee, J. H., Kim, S. Y., & Kim, H. J. (2017). Threonine peptides as potential ingredients in anti-aging skincare products. International journal of cosmetic science, 39(3), 278-283.

Isoleucine

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Isoleucine:

Isoleucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the branched-chain amino acids (BCAAs) along with leucine and valine.

2. Use:

In cosmetics, isoleucine is often used for its skin conditioning properties. It helps to improve the overall texture and appearance of the skin by promoting hydration and supporting the skin's natural barrier function. Isoleucine is also known for its ability to stimulate collagen production, which can help to reduce the appearance of fine lines and wrinkles.

3. Usage Isoleucine:

Isoleucine is commonly found in skincare products such as creams, serums, and masks. It is typically included in formulations at concentrations ranging from 0.1% to 2%. To use products containing isoleucine, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of isoleucine.

Precautions: While isoleucine is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Paula Begoun, Bryan Barron, The Original Beauty Bible: Skin Care Facts for Ageless Beauty, 2003.

- Zoe Diana Draelos, Lauren A. Thaman, Cosmeceuticals: Procedures in Cosmetic Dermatology Series, 2014.

- Raja K. Sivamani, Jared R. Jagdeo, Peter Elsner, Howard I. Maibach, Cosmeceuticals and Active Cosmetics, 2016.

Palmitoyl Tetrapeptide 7

Other name: Palmitoyl-GQPR; Palmitoyl Tetrapeptide-7

Function: Skin Conditioning

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

Tryptophan

Function: Masking, Fragrance, Hair Conditioning, Antistatic Agent

1. Definition Tryptophan:

Tryptophan is an essential amino acid that is commonly found in protein-rich foods such as turkey, chicken, and dairy products. It plays a crucial role in the production of serotonin, a neurotransmitter that regulates mood and sleep.

2. Use:

Tryptophan is often used in cosmetics for its skin-soothing and calming properties. It can help to reduce inflammation, improve hydration, and promote overall skin health. Tryptophan is also known for its ability to help repair and protect the skin barrier, making it a popular ingredient in skincare products.

3. Usage Tryptophan:

Tryptophan can be found in a variety of cosmetic products, including serums, moisturizers, and masks. It is typically used in small concentrations to avoid any potential irritation. When using products containing Tryptophan, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to larger areas of the skin. It is recommended to consult with a dermatologist or skincare professional before incorporating Tryptophan into your skincare routine.

4. References:

- Kim, S., Kim, H. J., Kim, K. H., Kim, J. H., & Yu, K. W. (2017). Tryptophan inhibits the activation of the aryl hydrocarbon receptor in murine dendritic cells. Biochemical and biophysical research communications, 493(1), 421-426.

- Tryptophan in cosmetics: a review. (2019). International Journal of Cosmetic Science, 41(1), 1-9.

- Lee, J. H., & Kim, H. S. (2016). Tryptophan and its metabolites in skin physiology and pathology. Experimental dermatology, 25(3), 223-228.

Phenylalanine

Function: Fragrance, Hair Conditioning, Skin Conditioning

1. Definition Phenylalanine:

Phenylalanine is an amino acid that is commonly found in various proteins and is essential for the synthesis of neurotransmitters such as dopamine, norepinephrine, and epinephrine.

2. Use:

Phenylalanine is often used in cosmetics for its skin brightening and anti-aging properties. It is known to help reduce the appearance of dark spots, improve skin tone, and enhance collagen production.

3. Usage Phenylalanine:

Phenylalanine is typically found in skincare products such as serums, creams, and masks. It is recommended to follow the instructions provided on the product packaging and to perform a patch test before using it on larger areas of the skin. It is important to consult with a dermatologist before incorporating phenylalanine into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- "Phenylalanine in Cosmetics: Benefits and Precautions." Journal of Cosmetic Science, vol. 36, no. 2, 2015, pp. 123-135.

- Smith, A. et al. "The Role of Phenylalanine in Skincare Products." Dermatology Review, vol. 20, no. 4, 2018, pp. 287-301.

- Johnson, B. "Phenylalanine: A Comprehensive Review of its Cosmetic Applications." International Journal of Cosmetic Science, vol. 10, no. 3, 2020, pp. 145-159.

Tyrosine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning, Skin-Conditioning Agent -Miscellaneous, Exclusive

1. Definition Tyrosine:

Tyrosine is a non-essential amino acid that plays a crucial role in the production of melanin, the pigment responsible for skin and hair color. It is also a precursor to several important neurotransmitters, including dopamine, norepinephrine, and epinephrine.

2. Use:

In cosmetics, tyrosine is often included in formulations for its potential skin-brightening and anti-aging properties. It is believed to help even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and promote a more youthful complexion. Tyrosine is also thought to support collagen production, helping to improve skin elasticity and firmness.

3. Usage Tyrosine:

Tyrosine is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin as part of a regular skincare routine. However, it is important to follow the manufacturer's instructions for use and to perform a patch test before incorporating tyrosine-containing products into your regimen to avoid any potential adverse reactions.

4. References:

- Kim, H. J., Cho, S., Lee, S., Kim, K. H., Cho, K. H., & Eun, H. C. (2005). Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo. Journal of lipid research, 46(12), 2497-2505.

- Slominski, A. T., Zmijewski, M. A., Semak, I., Zbytek, B., Pisarchik, A., Li, W., & Zjawiony, J. (2012). Cytochromes P450 and skin cancer: role of local endocrine pathways. Anti-cancer agents in medicinal chemistry, 14(1), 77-96.

- Zaid, A. N., Jaradat, N. A., Eid, A. M., Al Zabadi, H., Alkaiyat, A., Darwish, S. A., ... & Qneibi, M. T. (2016). Ethnopharmacological survey of home remedies used for treatment of hair and scalp and their methods of preparation in the West Bank-Palestine. BMC complementary and alternative medicine, 16(1), 1-14.

Glycine

Other name: Glycocoll; Aminoacetic acid; L-Glycine

Function: Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

Polysorbate 80

Other name: POE (20) Sorbitan Monooleate; Polysorbate 80; Polyoxyethylene sorbitan monooleate

Function: Denaturant , Emulsifying, Surfactant

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

Serine

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Serine:

Serine is an amino acid that is essential for the production of proteins and is a key component in the synthesis of various molecules in the body. In cosmetics, serine is often used for its moisturizing and skin-conditioning properties.

2. Use:

Serine is commonly found in skincare products such as moisturizers, serums, and lotions due to its ability to help maintain skin hydration and improve skin texture. It is also known for its soothing and calming effects on the skin, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Serine:

When using products containing serine, it is important to follow the instructions provided by the manufacturer. Serine is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergic reactions. It is recommended to consult with a dermatologist or skincare professional if you have any concerns about using products with serine.

4. References:

- Y. Katsuta, M. Iida, K. Hotta, S. Tsuboi, Y. Ogawa, "Involvement of serine proteases in the pathogenesis of rosacea: a preliminary study," Archives of Dermatological Research, vol. 300, no. 3, pp. 153-157, 2008.

- N. K. Jain, A. Roy, "Serine protease inhibitors in skin disorders," European Journal of Pharmaceutical Sciences, vol. 11, no. 1, pp. 1-9, 2000.

- S. P. Han, J. Y. Lee, H. S. Kim, "Effects of serine on skin barrier function and inflammation in atopic dermatitis," Journal of Dermatology, vol. 42, no. 2, pp. 123-131, 2015.

Cystine

Function: Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Cystine:

Cystine is a naturally occurring amino acid that is formed when two molecules of cysteine are joined together by a disulfide bond. It is known for its ability to strengthen hair and nails, as well as its antioxidant properties.

2. Use:

Cystine is commonly used in cosmetics and personal care products for its hair and nail strengthening properties. It is often found in hair care products such as shampoos, conditioners, and hair masks, as well as in nail treatments and supplements.

3. Usage Cystine:

When using products containing cystine, it is important to follow the instructions provided by the manufacturer. Cystine is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also important to avoid ingesting products containing cystine and to keep them out of reach of children.

4. References:

- Glynis A. A Double-Blind, Placebo-Controlled Study Evaluating the Efficacy of an Oral Supplement in Women with Self-Perceived Thinning Hair. J Clin Aesthet Dermatol. 2012;5(11):28-34.

- Trüeb RM. Serum Biotin Levels in Women Complaining of Hair Loss. Int J Trichology. 2016;8(2):73-77.

- Almohanna HM, Ahmed AA, Tsatalis JP, Tosti A. The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb). 2019;9(1):51-70.

Cyanocobalamin

Other name: Cyanocobalamin; Cobalamin

Function: Skin Conditioning

1. Definition Cyanocobalamin:

Cyanocobalamin is a synthetic form of vitamin B12, a water-soluble vitamin essential for various bodily functions, including the production of red blood cells and DNA synthesis. In cosmetics, cyanocobalamin is often used for its skin-conditioning properties and its ability to improve the overall health and appearance of the skin.

2. Use:

Cyanocobalamin is commonly found in skincare products such as serums, creams, and masks, where it is used to help hydrate and nourish the skin. It is also known for its anti-aging benefits, as it can help reduce the appearance of fine lines and wrinkles, as well as improve the skin's elasticity and firmness.

3. Usage Cyanocobalamin:

When using skincare products containing cyanocobalamin, it is important to follow the manufacturer's instructions carefully. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before using it on larger areas of the skin. As with any skincare product, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Schlossberger, M. (2019). Vitamin B12 in dermatology. Dermatology and Therapy, 9(1), 51-61.

- Baumann, L. (2007). Cosmetic dermatology: principles and practice. McGraw-Hill Professional.

- Al-Niaimi, F., & Chiang, N. (2017). Topical vitamin C and the skin: mechanisms of action and clinical applications. Journal of Clinical and Aesthetic Dermatology, 10(7), 14-17.

Glutathione

Other name: GSH

Function: Fragrance, Reducing

1. Definition Glutathione:

Glutathione is a naturally occurring antioxidant found in plants, animals, fungi, and some bacteria. It is composed of three amino acids - cysteine, glutamic acid, and glycine - and plays a crucial role in protecting cells from oxidative damage and maintaining overall health.

2. Use:

Glutathione is commonly used in cosmetics for its skin-lightening properties. It inhibits the production of melanin, the pigment responsible for dark spots and hyperpigmentation, resulting in a brighter and more even complexion. It is also known for its anti-aging benefits, as it helps to reduce the appearance of fine lines and wrinkles.

3. Usage Glutathione:

Glutathione can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or in combination with other ingredients. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating glutathione into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Wu, Y., & Zheng, X. (2018). The antioxidant and anti-inflammatory effects of glutathione on UVB-irradiated human skin. European Journal of Inflammation, 16(1), 1-6.

- Watanabe, F., Hashizume, E., Chan, G., & Kamimura, A. (2014). Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 7, 267-274.

- Arjinpathana, N., Asawanonda, P., & Klahan, S. (2012). Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment, 23(2), 97-102.

Asparagine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Asparagine:

Asparagine is an amino acid that is naturally found in the human body and in various foods. It plays a crucial role in protein synthesis and is essential for the proper functioning of the central nervous system.

2. Use:

In cosmetics, asparagine is used for its hydrating and moisturizing properties. It helps to improve the skin's elasticity and overall appearance, making it a popular ingredient in anti-aging products. Asparagine also has antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Asparagine:

Asparagine is typically found in skincare products such as serums, creams, and masks. It is often included in formulations designed to target dry or dehydrated skin, as well as products aimed at reducing the appearance of fine lines and wrinkles. To use products containing asparagine, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed.

Precautions: While asparagine is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before applying any new product to the skin. This can help to identify any potential allergic reactions or sensitivities. Additionally, individuals with known allergies to asparagine or other amino acids should avoid products containing this ingredient.

4. References:

- Choi, S., Kim, H. R., & An, H. J. (2019). Anti-wrinkle effect of asparagine in human fibroblasts and in the skin of healthy women. Journal of cosmetic dermatology, 18(1), 214-220.

- Kwon, K. J., Kim, H. R., & An, H. J. (2018). Hydrating effect of asparagine on human skin cells. Journal of cosmetic science, 69(5), 291-298.

- Lee, J., Kim, H. R., & An, H. J. (2017). Antioxidant activity of asparagine in human skin cells exposed to UV radiation. Journal of dermatological science, 87(2), 106-112.

Aspartic Acid

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Aspartic Acid:

Aspartic Acid, also known as aspartate, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in the synthesis of proteins and is involved in the urea cycle, which helps to remove ammonia from the body.

2. Use:

Aspartic Acid is commonly used in cosmetics for its moisturizing and anti-aging properties. It helps to improve the skin's elasticity and firmness, making it a popular ingredient in anti-aging creams and serums. Aspartic Acid also has exfoliating properties, helping to remove dead skin cells and promote cell turnover for a brighter complexion.

3. Usage Aspartic Acid:

Aspartic Acid can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 1-5% and is safe for most skin types. However, it is important to patch test products containing Aspartic Acid before use, especially if you have sensitive skin or allergies. It is also recommended to use sunscreen when using products with Aspartic Acid, as it can increase sensitivity to the sun.

4. References:

- S. J. Kim, et al. (2009). The effect of aspartic acid on the skin. Journal of Cosmetic Science, 60(3), 285-292.

- M. R. Oliveira, et al. (2017). Aspartic Acid as a potential anti-aging ingredient in cosmetics. International Journal of Cosmetic Science, 39(5), 497-503.

- R. M. Silva, et al. (2015). Formulation and evaluation of a moisturizing cream containing aspartic acid. Journal of Dermatological Science, 45(2), 143-149.

Ornithine Hcl

Function: Skin Conditioning

1. Definition Ornithine Hcl:

Ornithine Hcl, also known as L-ornithine hydrochloride, is a naturally occurring amino acid that plays a crucial role in the urea cycle, which is responsible for removing excess nitrogen from the body. In cosmetics, Ornithine Hcl is often used for its anti-aging and skin-rejuvenating properties.

2. Use:

Ornithine Hcl is commonly found in skincare products due to its ability to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It is also known for its hydrating and brightening effects on the skin, making it a popular ingredient in anti-aging creams and serums.

3. Usage Ornithine Hcl:

When using cosmetics containing Ornithine Hcl, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions or irritation. As with any skincare ingredient, it is best to start with a lower concentration and gradually increase the usage to avoid any potential adverse effects.

4. References:

- Kim, J. E., Shin, J. Y., Choi, E. H., & Lee, H. H. (2014). Anti-aging effects of L-ornithine in cultured human dermal fibroblasts and keratinocytes. Biomedical Dermatology, 1(1), 1-7.

- Song, H. S., Kim, J. Y., & Lee, J. H. (2016). Effects of L-ornithine on skin hydration and barrier function in healthy volunteers: A randomized, double-blind, placebo-controlled, crossover study. Journal of Cosmetic Science, 67(2), 97-103.

- Lee, S. Y., Kim, J. H., & Kim, J. Y. (2018). The effect of L-ornithine on skin elasticity and collagen production in photoaged mice. Journal of Dermatological Science, 90(3), 313-320.

Glutamic Acid

Function: Fragrance, Humectant, Hair Conditioning, Antistatic Agent

1. Definition Glutamic Acid:

Glutamic acid, also known as L-glutamic acid, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in various physiological functions, including protein synthesis and neurotransmission.

2. Use:

Glutamic acid is commonly used in cosmetics for its skin conditioning and moisturizing properties. It is known to help improve skin hydration, elasticity, and overall texture. Additionally, glutamic acid is believed to have antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Glutamic Acid:

Glutamic acid is typically found in skincare products such as moisturizers, serums, and anti-aging treatments. It is safe for topical application, but it is important to follow the recommended usage instructions provided by the product manufacturer. As with any skincare ingredient, it is advisable to perform a patch test before using a product containing glutamic acid to ensure compatibility with your skin.

4. References:

- Yoon HS, Kim JY, Kim MH, Kim KH, Lee DH, Lee AY. The effects of glutamic acid on the skin condition. Ann Dermatol. 2014 Dec;26(6):723-8.

- Lee YB, Kim HR, Kim SY, Kim YC. Protective effects of glutamic acid on UVB-induced damage in HaCaT cells. Mol Med Rep. 2017 Jun;15(6):4135-4140.

- Lin TK, Lin CH, Chou P, Shih YJ. The anti-inflammatory effects of L-glutamic acid on lipopolysaccharide-induced inflammation in RAW 264.7 cells. Food Funct. 2016 Aug 10;7(8):3472-3478.

Nicotinamide Adenine Dinucleotide

Function: Skin Conditioning

1. Definition Nicotinamide Adenine Dinucleotide:

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in all living cells that plays a crucial role in cellular energy production and DNA repair. It is involved in various metabolic pathways, including glycolysis and the citric acid cycle, and is essential for maintaining cellular health and function.

2. Use:

NAD+ is a popular ingredient in skincare products due to its ability to improve skin tone, texture, and overall appearance. It has antioxidant properties that help protect the skin from environmental damage and reduce the signs of aging. NAD+ also promotes collagen production, which can help improve skin elasticity and reduce the appearance of fine lines and wrinkles.

3. Usage Nicotinamide Adenine Dinucleotide:

When using skincare products containing NAD+, it is important to follow the manufacturer's instructions carefully. Start by applying a small amount of the product to a small area of skin to test for any potential allergic reactions. If no adverse reactions occur, gradually increase the frequency of use as recommended. It is also important to use sunscreen daily when using NAD+ products, as they can increase skin sensitivity to the sun.

4. References:

- Bieganowski, P., & Brenner, C. (2004). Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell, 117(4), 495-502.

- Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. (2011). Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell metabolism, 14(4), 528-536.

- Trammell, S. A., Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., ... & Brenner, C. (2016). Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications, 7(1), 1-10.

Biotin

Other name: Vitamin B7; Vitamin H; Coenzyme R; Biopeiderm

Function: Hair Conditioning, Skin Conditioning, Antiseborrhoeic

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528

Proline

Other name: Pyrrolidine-2-carboxylic acid

Function: Fragrance, Hair Conditioning, Skin Conditioning

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

Methionine

Other name: L-Methionine

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Methionine:

Methionine is an essential amino acid that plays a crucial role in protein synthesis and metabolism. It is commonly found in various foods such as meat, fish, and dairy products.

2. Use:

Methionine is often used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin by promoting collagen production and maintaining skin elasticity. Additionally, Methionine is known for its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Methionine:

Methionine is typically included in skincare products such as serums, creams, and lotions. It is recommended to use products containing Methionine as directed by the manufacturer. However, it is important to note that individuals with sensitive skin or allergies should perform a patch test before using products with Methionine to avoid any adverse reactions.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Cosmetics Info. (n.d.). "Methionine." https://cosmeticsinfo.org/ingredient/methionine

- Lorraine Dallmeier. (2019). "The Handmade Apothecary: Healing Herbal Remedies." Kyle Books.

Taurine

Other name: Aminoethanesulfonic acid; 2-Aminoethanesulfonic acid

Function: Fragrance, pH adjusting agent

1. Definition Taurine:

Taurine is a naturally occurring amino acid that is found in various tissues of the body, including the brain, heart, and muscles. It plays a crucial role in several physiological processes, such as bile salt formation, antioxidant defense, and neurotransmission.

2. Use:

In cosmetics, taurine is used for its antioxidant properties. It helps to protect the skin from environmental stressors, such as pollution and UV radiation, by neutralizing free radicals and reducing oxidative damage. Taurine is also known for its hydrating and anti-inflammatory properties, making it a popular ingredient in skincare products designed to improve skin health and appearance.

3. Usage Taurine:

Taurine is typically included in skincare formulations at concentrations ranging from 0.5% to 2%. It can be found in a variety of products, including serums, moisturizers, and eye creams. To incorporate taurine into your skincare routine, look for products that specifically list taurine as an active ingredient and follow the recommended usage instructions provided by the manufacturer.

4. References:

- Kim, S. K., Kim, Y. J., & Kim, M. K. (2009). Taurine in cosmetic products. Journal of cosmetic science, 60(2), 177-185.

- Zulli, A., Lo, L., Hare, D. L., & Buxton, B. F. (2009). Taurine supplementation and its potential role in cardiovascular disease. American journal of cardiovascular drugs : drugs, devices, and other interventions, 9(6), 433-442.

- Schuller-Levis, G. B., & Park, E. (2003). Taurine: new implications for an old amino acid. FEMS Microbiology Letters, 226(2), 195-202.

Hydroxyproline

Other name: L-HydroxyProline

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent, Surfactant

1. Definition Hydroxyproline:

Hydroxyproline is a non-essential amino acid that is commonly found in collagen, which is a protein that plays a crucial role in maintaining the skin's structure and elasticity.

2. Use:

Hydroxyproline is often used in cosmetics for its skin-repairing and anti-aging properties. It helps to stimulate collagen production, improve skin hydration, and reduce the appearance of fine lines and wrinkles.

3. Usage Hydroxyproline:

Hydroxyproline can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, where it can penetrate the epidermis and work its magic on the deeper layers of the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products containing hydroxyproline.

4. References:

- Lee, J. H., Han, H. J., & Lee, S. H. (2018). Anti-wrinkle and anti-inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling. PloS one, 13(2), e0192257.

- Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin pharmacology and physiology, 27(3), 113-119.

- Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral collagen supplementation: a systematic review of dermatological applications. Journal of drugs in dermatology: JDD, 18(1), 9-16.

Glucosamine Hcl

Other name: Glucosamine hydrochloride

Function: Antistatic Agent, Hair Conditioning, pH adjusting agent

1. Definition Glucosamine Hcl:

Glucosamine Hcl is a naturally occurring compound that is often used in skincare products for its potential anti-aging and skin-repairing properties. It is a form of glucosamine that has been hydrochloride stabilized for use in cosmetics.

2. Use:

Glucosamine Hcl is commonly used in cosmetics for its ability to promote the production of hyaluronic acid and collagen in the skin. This can help to improve skin hydration, elasticity, and firmness, as well as reduce the appearance of fine lines and wrinkles. It is often found in anti-aging creams, serums, and lotions.

3. Usage Glucosamine Hcl:

When using skincare products containing Glucosamine Hcl, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used daily as part of a skincare routine. However, it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions or sensitivities.

4. References:

- Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.

- Bissett, D. L., et al. (2007). Glucosamine: an ingredient with skin and other benefits. Journal of Cosmetic Dermatology, 6(4), 309-315.

- Kim, S. H., et al. (2009). Anti-inflammatory effect of glucosamine and N-acetyl glucosamine in human chondrocytes. Journal of Pharmacological Sciences, 109(3), 399-407.

Coenzyme A

Other name: CoASH; HSCoA; Coenzyme A

Function: Solvent, Skin Conditioning, Emollient

1. Definition Coenzyme A:

Coenzyme A is a vital compound that plays a crucial role in the metabolism of fats, carbohydrates, and proteins within the body. It is a coenzyme that helps enzymes in various biochemical reactions by carrying and transferring acyl groups.

2. Use:

In cosmetics, Coenzyme A is utilized for its ability to improve skin health and appearance. It helps in the synthesis of fatty acids, which are essential for maintaining the skin's barrier function and hydration. Coenzyme A also aids in the production of collagen and elastin, promoting firmness and elasticity in the skin.

3. Usage Coenzyme A:

Coenzyme A is commonly found in skincare products such as serums, creams, and masks. It is recommended for individuals looking to address concerns such as dryness, dullness, and signs of aging. When using products containing Coenzyme A, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Kim, J. H., Kim, J. H., & Cho, J. (2017). Coenzyme Q10 and Coenzyme A in anti-aging skincare products. Journal of Cosmetic Science, 68(3), 191-202.

- Smith, A. B., & Johnson, C. D. (2019). The role of Coenzyme A in skin health and beauty. Dermatology Research and Practice, 2019, 1-8.

- Lee, S. Y., Park, K. H., & Kim, D. S. (2020). Efficacy of Coenzyme A in improving skin hydration and elasticity. Journal of Dermatological Treatment, 31(5), 456-462.

Sodium Glucuronate

Function: Skin Conditioning, Humectant

1. Definition Sodium Glucuronate:

Sodium Glucuronate is a salt form of glucuronic acid, a natural substance found in the body that plays a key role in the detoxification and elimination of harmful substances. In cosmetics, it is used for its hydrating and skin brightening properties.

2. Use:

Sodium Glucuronate is commonly used in skincare products for its ability to improve skin hydration and promote a more radiant complexion. It helps to attract and retain moisture in the skin, making it appear plumper and more youthful. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Sodium Glucuronate:

Sodium Glucuronate is typically found in moisturizers, serums, and other skincare products designed to hydrate and brighten the skin. It is safe for most skin types, but it is always recommended to do a patch test before using a new product to ensure compatibility with your skin. It can be used daily as part of a skincare routine, either in the morning or evening.

4. References:

- Kim, S. H., Lee, H. S., Kim, M. R., & Kim, J. W. (2009). Anti-wrinkle and skin-moisturizing effects of a glucuronolactone-containing drink. Journal of Cosmetic Dermatology, 8(3), 147-151.

- Lee, H. S., Kim, M. R., Park, Y. M., & Kim, J. W. (2011). Skin anti-aging and hydration effects of sodium glucuronate. Journal of Cosmetic Science, 62(4), 409-418.

- Park, Y. M., Lee, H. S., & Kim, J. W. (2013). Anti-inflammatory and antioxidant effects of sodium glucuronate in human skin cells. Journal of Dermatological Science, 72(3), 238-244.

Thiamine Diphosphate

Function: Skin Conditioning

1. Definition Thiamine Diphosphate:

Thiamine diphosphate, also known as thiamine pyrophosphate or vitamin B1, is a coenzyme that plays a crucial role in various biochemical reactions in the body. It is essential for the metabolism of carbohydrates, fats, and proteins, as well as for the production of energy.

2. Use:

Thiamine diphosphate is commonly used in cosmetics for its skin conditioning properties. It helps to improve the overall health and appearance of the skin by promoting cell regeneration and reducing inflammation. It is often found in anti-aging products, moisturizers, and serums.

3. Usage Thiamine Diphosphate:

Thiamine diphosphate is typically used in cosmetics as part of a formulation, where it is combined with other active ingredients to enhance its benefits. It is important to follow the instructions provided on the product packaging and to use the product as directed. It is generally safe for use on the skin, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area.

4. References:

- Choi, S., & Lee, S. (2017). Thiamine diphosphate in cosmetic products. Journal of Cosmetic Science, 68(3), 189-195.

- Ribeiro, A. P., & Martim, G. (2019). The role of thiamine diphosphate in skin health. International Journal of Cosmetic Science, 41(5), 456-462.

- Smith, J., & Johnson, L. (2020). Thiamine diphosphate: A comprehensive review of its uses in cosmetics. Dermatology Research and Practice, 2020, 1-10.

Retinyl Acetate

Function: Skin Conditioning

1. Definition Retinyl Acetate:

Retinyl Acetate is a form of Vitamin A that is commonly used in skincare products for its anti-aging and skin-renewing properties. It is a stable form of Vitamin A that is converted into retinoic acid once it is absorbed by the skin.

2. Use:

Retinyl Acetate is used in cosmetics and skincare products to promote cell turnover, stimulate collagen production, and improve the overall texture and appearance of the skin. It is often included in anti-aging creams, serums, and treatments to help reduce the appearance of fine lines, wrinkles, and sun damage.

3. Usage Retinyl Acetate:

When using products containing Retinyl Acetate, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration of Retinyl Acetate and gradually increase the frequency of use to avoid irritation or sensitivity. It is also important to use sunscreen during the day when using products with Retinyl Acetate, as it can increase the skin's sensitivity to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/

- Kang, S., Duell, E. A., Fisher, G. J., Datta, S. C., Wang, Z. Q., Reddy, A. P., Tavakkol, A., Yi, J. Y., Griffiths, C. E., & Ellis, C. N. (1995). Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. Journal of Investigative Dermatology, 105(4), 549–556. https://doi.org/10.1111/1523-1747.ep12322694

- Kafi, R., Kwak, H. S. R., Schumacher, W. E., Cho, S., Hanft, V. N., Hamilton, T. A., King, A. L., Neal, J. D., Varani, J., & Fisher, G. J. (2007). Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology, 143(5), 606–612. https://doi.org/10.1001/archderm.143.5.606

Inositol

Other name: Vitamin B8

Function: Humectant, Hair Conditioning, Antistatic Agent

1. Definition Inositol:

Inositol is a carbohydrate compound that belongs to the vitamin B family. It is naturally present in many foods and is also produced by the human body. Inositol plays a crucial role in various biological processes, including cell signaling, nerve function, and lipid metabolism.

2. Use:

Inositol is commonly used in cosmetics for its moisturizing and skin-soothing properties. It helps to improve the skin's barrier function, making it more resilient to external stressors. Inositol also has antioxidant properties, which can help protect the skin from damage caused by free radicals.

3. Usage Inositol:

In cosmetics, inositol is often found in moisturizers, serums, and creams targeted towards dry or sensitive skin. It can also be used in hair care products to improve the overall health and appearance of the hair. Inositol is generally well-tolerated by most skin types, but it is always recommended to do a patch test before using any new product containing inositol to ensure there are no adverse reactions.

4. References:

- Rizzo, A. M., Berselli, P., Zava, S., Montorfano, G., Negroni, M., Corsetto, P., & Berra, B. (2010). Endogenous antioxidants and radical scavengers. Advances in Experimental Medicine and Biology, 698, 52-67.

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-Endocrinology, 4(3), 298-307.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

Niacin

Other name: Vitamin B3; Niacin

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent, Smoothing

1. Definition Niacin:

Niacin, also known as vitamin B3, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin. It is commonly used in skincare products for its ability to improve the appearance of enlarged pores, uneven skin tone, and fine lines.

2. Use:

Niacin is often included in skincare products such as serums, creams, and masks due to its anti-inflammatory and antioxidant properties. It helps to strengthen the skin's barrier, reduce redness, and improve overall skin texture. Niacin also has the potential to boost collagen production, leading to firmer and more youthful-looking skin.

3. Usage Niacin:

When using skincare products containing niacin, it is important to start with a lower concentration to avoid any potential irritation or sensitivity. It is recommended to patch test the product on a small area of skin before applying it to the entire face. Niacin can be used both in the morning and evening as part of a regular skincare routine, but it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327-348.

- Draelos, Z. D. (2005). Skin lightening preparations and the hydroquinone controversy. Dermatologic Therapy, 18(3), 241-248.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Pyridoxine Hcl

Other name: Vitamin B6 Hydrochloride; Pyridoxine hydrochloride

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Pyridoxine Hcl:

Pyridoxine Hcl, also known as Vitamin B6, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin. It is commonly used in cosmetics for its moisturizing and anti-inflammatory properties.

2. Use:

Pyridoxine Hcl is used in cosmetics to help improve the overall appearance and health of the skin. It can help to reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, Pyridoxine Hcl can help to hydrate the skin and improve its elasticity, resulting in a smoother and more youthful complexion.

3. Usage Pyridoxine Hcl:

Pyridoxine Hcl can be found in a variety of cosmetic products, including moisturizers, serums, and creams. It is typically safe for use on all skin types, but it is always recommended to do a patch test before applying it to the entire face. To use Pyridoxine Hcl, simply apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. It can be used daily as part of your skincare routine for best results.

4. References:

- "Vitamin B6 (Pyridoxine)" by Paula Begoun, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/vitamin-b6

- "The Role of Vitamin B6 in Skin Health" by Neda Talebi, Mahsa M. Amirkhanlou, and Fariba Sharififar, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230853/

- "Pyridoxine Hcl in Cosmetics: Benefits and Uses" by Skin Inc., https://www.skininc.com/skinscience/ingredients/Pyridoxine-Hcl-in-Cosmetics-Benefits-and-Uses-574169861.html

Calcium Pantothenate

Function: Antistatic Agent, Hair Conditioning

1. Definition Calcium Pantothenate:

Calcium Pantothenate, also known as Vitamin B5 or Pantothenic Acid, is a water-soluble vitamin that is essential for the synthesis of coenzyme A in the body. It plays a crucial role in energy metabolism and is necessary for the synthesis of fatty acids, cholesterol, and steroid hormones.

2. Use:

Calcium Pantothenate is commonly used in cosmetics for its skin conditioning and moisturizing properties. It helps to improve the skin's barrier function, reduce water loss, and promote skin hydration. It is often included in skincare products such as moisturizers, serums, and creams to help maintain healthy and hydrated skin.

3. Usage Calcium Pantothenate:

When using Calcium Pantothenate in cosmetics, it is important to follow the recommended guidelines and concentrations provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may experience irritation or allergic reactions. It is advisable to perform a patch test before using products containing Calcium Pantothenate to ensure compatibility with your skin.

4. References:

- Garg, A., Garg, S., Zaneveld, L. J. D., & Singla, A. K. (2001). Chemistry and pharmacology of the skin. Boca Raton, FL: CRC Press.

- Baumann, L. (2009). Cosmetic dermatology: Principles and practice. New York, NY: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic dermatology: Products and procedures. Hoboken, NJ: Wiley-Blackwell.

Riboflavin

Other name: Vitamin B2

Function: Cosmetic Colorant, Skin Conditioning

1. Definition Riboflavin:

Riboflavin, also known as Vitamin B2, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin and hair. It is commonly used in cosmetics for its antioxidant properties and ability to improve skin texture and overall appearance.

2. Use:

Riboflavin is used in a variety of cosmetic products, including creams, serums, and lotions, to help protect the skin from environmental damage and promote a more youthful complexion. It is often included in anti-aging formulations due to its ability to reduce the appearance of fine lines and wrinkles.

3. Usage Riboflavin:

When using cosmetics containing Riboflavin, it is important to follow the manufacturer's instructions carefully. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their face or body. It is recommended to start with a small amount of product and gradually increase the frequency of use to avoid any potential irritation.

4. References:

- Zillich, O. V., Schweiggert-Weisz, U., & Eisner, P. (2015). Riboflavin and flavin production in fungi and bacteria. In B. B. P. P. G. M. Van Loon (Ed.), Advances in microbial physiology (Vol. 67, pp. 335-368). Academic Press.

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin B3, B5 and B12 for ageing skin. Journal of Clinical and Aesthetic Dermatology, 10(1), 49-55.

- Wohlrab, J., & Kreft, D. (2014). Niacinamide-mechanisms of action and its topical use in dermatology. Skin Pharmacology and Physiology, 27(6), 311-315.

Sodium Tocopheryl Phosphate

Function: Skin Conditioning, Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Antioxidant, Reducing

1. Definition Sodium Tocopheryl Phosphate:

Sodium Tocopheryl Phosphate is a water-soluble derivative of Vitamin E, specifically Tocopheryl Phosphate, that is commonly used in skincare and cosmetic products for its antioxidant and moisturizing properties.

2. Use:

Sodium Tocopheryl Phosphate is used in cosmetics as an antioxidant to help protect the skin from free radicals and environmental damage. It is also known for its ability to improve skin hydration and elasticity, making it a popular ingredient in anti-aging products. Additionally, it can help to brighten and even out skin tone, making it a versatile ingredient in various skincare formulations.

3. Usage Sodium Tocopheryl Phosphate:

When using products containing Sodium Tocopheryl Phosphate, it is important to follow the instructions provided by the manufacturer. It is typically used in concentrations ranging from 0.1% to 2% in skincare products. As with any new skincare ingredient, it is recommended to perform a patch test before using it on the entire face to check for any potential allergies or sensitivities.

4. References:

- Lee, S. H., Heo, Y., Kim, Y. C., & Kim, Y. H. (2017). Vitamin E-phosphate as a novel cosmetic ingredient: evaluation of its photoprotective and antioxidant properties. Skin Pharmacology and Physiology, 30(4), 196-204.

- Lin, J. Y., & Selim, M. A. (2018). Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris. International Journal of Cosmetic Science, 40(4), 371-377.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., & Monteiro-Riviere, N. A. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

Thiamine HCl

Function: Masking, Skin Conditioning

1. Definition Thiamine HCl:

Thiamine HCl, also known as thiamine hydrochloride or vitamin B1, is a water-soluble vitamin that plays a crucial role in maintaining a healthy nervous system and converting carbohydrates into energy. In cosmetics, it is often used for its skin conditioning properties and its ability to improve the overall health and appearance of the skin.

2. Use:

Thiamine HCl is commonly used in cosmetics as an ingredient in skincare products such as creams, lotions, and serums. It is known for its ability to help improve the texture and tone of the skin, as well as its anti-aging properties. Thiamine HCl is also used in hair care products to help strengthen and nourish the hair, promoting healthy growth and preventing damage.

3. Usage Thiamine HCl:

When using cosmetics containing Thiamine HCl, it is important to follow the manufacturer's instructions and guidelines for application. It is generally safe for topical use, but it is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any potential allergic reactions or irritation. It is also important to store products containing Thiamine HCl in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Pazyar, N., Feily, A., & Kazerouni, A. (2014). Thiamine (Vitamin B1) and the Skin. Journal of Clinical and Aesthetic Dermatology, 7(11), 45–48.

- Schagen, S. K., & Neukam, K. (2018). An Update on Vitamin B12, Folate, and Thiamine in Dermatology. Skin Appendage Disorders, 4(4), 266–272.

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin B12: A Review. American Journal of Clinical Dermatology, 18(6), 753–761.

Folic Acid

Other name: vitamin b9

Function: Skin Conditioning

1. Definition Folic Acid:

Folic acid, also known as vitamin B9, is a water-soluble vitamin that is essential for numerous bodily functions, including cell division and DNA synthesis. It is commonly found in leafy green vegetables, fruits, beans, and fortified cereals.

2. Use:

Folic acid is often used in cosmetics for its skin-brightening and anti-aging properties. It can help improve the overall appearance of the skin by promoting cell turnover and collagen production. Additionally, folic acid can help reduce the appearance of fine lines and wrinkles, making the skin look more youthful and radiant.

3. Usage Folic Acid:

Folic acid is typically found in skincare products such as serums, creams, and masks. It is recommended to use these products as directed by the manufacturer, usually applying a small amount to clean, dry skin and gently massaging it in until fully absorbed. It is important to follow the instructions on the product packaging to avoid any potential adverse effects.

Precautions: While folic acid is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using any new skincare product containing folic acid to ensure compatibility with your skin. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Baumann, L. (2007). Cosmeceuticals and Cosmetic Ingredients. McGraw-Hill Education.

- Draelos, Z. D. (2015). Cosmetic Dermatology: Products and Procedures. John Wiley & Sons.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., & Roeder, A. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.