Full ingredients list Fourth Ray A-Ha Moment Enzyme Mask

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Vitis Vinifera (Grape) Seed Oil (Skin Conditioning, Emollient)	Promotes Wound Healing Fungal Acne Trigger Good for oily skin
1 4	B	Glycolic Acid (pH adjusting agent, pH adjusting agent, Exfoliant)	Anti Aging Bad for sensitive skin Good for oily skin
1	A	Zea Mays (Corn) Starch (Skin Protecting, Abrasive, Absorbent, Viscosity Increasing Agent)	Bad for oily skin
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
1	A	Argania Spinosa (Argan) Kernel Oil (Skin Conditioning, Emollient)	Fungal Acne Trigger
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
1		Lactobacillus/Papaya Fruit Ferment Extract (Skin Conditioning, Hair Conditioning, Abrasive)
		Vaccinium Macrocarpon (Cranberry) Fruit Powder*
1	B	Cetearyl Olivate (Hair Conditioning)	Fungal Acne Trigger
1		Euterpe Oleracea Fruit Extract (Hair Conditioning)
1		Hylocereus Undatus Fruit Extract
1		Lycium Barbarum Fruit Extract (Skin Conditioning, Hair Conditioning, Astringent)
1 2	B	Citrus Limon (Lemon) Fruit Extract	Bad for sensitive skin Good for oily skin
1		Vaccinium Myrtillus Fruit Extract (Skin Conditioning)
1		Gluconolactone (Solvent, Fragrance, Humectant)	Anti Aging
1 4	B	Lactic Acid (Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant)	Anti Aging Bad for sensitive skin
1 3	B	Salicylic Acid (Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover)	Bad for sensitive skin Good for oily skin Acne fighting
1		Tartaric Acid (Masking, Fragrance, pH adjusting agent, pH adjusting agent, Exfoliant)	Anti Aging Bad for sensitive skin
1		Saccharum Officinarum (Sugar Cane) Extract (Skin Conditioning, Moisturising)
1		Acer Saccharum (Sugar Maple) Extract (Keratolytic)
1 2	B	Citrus Paradisi (Grapefruit) Fruit Extract (Skin Conditioning)
1	B	Citrus Clementina Fruit Extract (Skin Conditioning)
		Citrus Tangerina (Tangerine) Peel Extract
2 4	B	Citrus Aurantium Dulcis (Orange) Fruit Extract (Masking, Fragrance, Skin Conditioning)	Bad for sensitive skin
1 2	B	Citrus Aurantium Dulcis (Orange) Peel Extract
1		Myrciaria Dubia Fruit Extract (Skin Conditioning)
1		Opuntia Ficus Indica Seed Oil (Emollient)
		Punica Granatum Fruit Extract (Skin Conditioning)
1	A	Calendula Officinalis Flower Extract (Skin Conditioning, Masking, Perfuming)
1 6		Quartz (Abrasive)
1	A	Algin (Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding)	Bad for sensitive skin Bad for oily skin
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Sorbitan Olivate (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1		Leuconostoc/Radish Root Ferment Filtrate (Antimicrobial, Antidandruff Agent)
1	A	Aluminum Hydroxide (Humectant, Skin Protecting, Opacifying, Emollient, Viscosity Controlling)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	1,2-Hexanediol (Solvent)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1 3		Titanium Dioxide (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying)	UV Protection Good for sensitive skin

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Vitis Vinifera (Grape) Seed Oil

Other name: Vitis Vinifera Seed Oil; Grape Seed Oil

Function: Skin Conditioning, Emollient

1. Definition Vitis Vinifera (Grape) Seed Oil:

Vitis Vinifera (Grape) Seed Oil is a natural oil extracted from the seeds of grapes. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Grape seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is lightweight and easily absorbed by the skin, making it suitable for all skin types. The oil helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and protect against environmental damage.

3. Usage Vitis Vinifera (Grape) Seed Oil:

Grape seed oil can be used on its own as a facial oil or added to moisturizers, serums, and hair products. It can also be used as a carrier oil for essential oils. To use grape seed oil, simply apply a few drops to clean, damp skin or hair and massage gently until absorbed. It can be used daily as part of a skincare routine.

Precautions: While grape seed oil is generally considered safe for most skin types, it is always recommended to do a patch test before using any new product to check for any allergic reactions. People with grape allergies should avoid using grape seed oil. Additionally, it is important to store grape seed oil in a cool, dark place to prevent oxidation and maintain its quality.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.

- Meier, L., & Stange, R. (2008). The role of essential fatty acids in human health. Journal of pediatric gastroenterology and nutrition, 47, S41-S44.

- Sivakumar, G., & Balamurugan, S. (2019). A review on grape seed oil. Journal of Critical Reviews, 6(1), 1-6.

Glycolic Acid

Other name: Hydroxyacetic acid

Function: pH adjusting agent, pH adjusting agent, Exfoliant

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

See more: Unlocking the Power of Glycolic Acid in Skincare!!!

Zea Mays (Corn) Starch

Other name: Zea mays

Function: Skin Protecting, Abrasive, Absorbent, Viscosity Increasing Agent

1. Definition Zea Mays (Corn) Starch:

Zea Mays (Corn) Starch is a fine, white powder derived from the corn kernel. It is commonly used in cosmetics as a thickening agent, absorbent, and skin conditioning agent.

2. Use:

Corn starch is often used in cosmetics to help absorb excess oil and moisture, giving products a silky texture. It can also help to improve the spreadability of products and provide a smooth finish to the skin.

3. Usage Zea Mays (Corn) Starch:

Corn starch is commonly found in various cosmetic products such as powders, dry shampoos, and facial masks. It is generally considered safe for use on the skin, but it is always recommended to do a patch test before applying it to a larger area to check for any potential allergic reactions. It is important to avoid inhaling the powder during application to prevent respiratory irritation.

4. References:

- “Corn Starch in Cosmetics: Benefits, Uses, and Side Effects” by Dr. Anvita Bhargava, MD

- “The Role of Corn Starch in Formulating Cosmetics” by Dr. Samantha Jones, PhD

- “Safety Assessment of Zea Mays (Corn) Starch as Used in Cosmetics” by Cosmetic Ingredient Review

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Argania Spinosa (Argan) Kernel Oil

Function: Skin Conditioning, Emollient

1. Definition Argania Spinosa (Argan) Kernel Oil:

Argania Spinosa (Argan) Kernel Oil is a plant-derived oil extracted from the kernels of the Argan tree, native to Morocco. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Argan Kernel Oil is known for its moisturizing and nourishing properties, making it a versatile ingredient in cosmetics. It is commonly used in moisturizers, serums, hair oils, and masks to hydrate and soften the skin and hair. It is also believed to have anti-inflammatory and anti-aging benefits, helping to improve the overall health and appearance of the skin.

3. Usage Argania Spinosa (Argan) Kernel Oil:

When using Argan Kernel Oil in cosmetics, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or mixed with other ingredients to create customized skincare or haircare products. It is recommended to use a small amount initially and gradually increase the dosage as needed. Avoid contact with eyes and discontinue use if any irritation occurs.

4. References:

- Schmitt, L., Maranz, S., Akermi, M., & Delaveau, P. (2003). Effect of argan oil on platelet aggregation and bleeding time: a beneficial nutritional property. Journal of Nutritional Biochemistry, 14(4), 220-225.

- Ait-Ouazzou, A., Lorán, S., González-Ferrero, C., Aranda, C., Rota, C., Herrera, A., ... & Espina, L. (2011). Chemical composition and antifungal activity of essential oils from Moroccan medicinal plants. Journal of medical plants research, 5(23), 5728-5736.

- Khallouki, F., Younos, C., Soulimani, R., Oster, T., Charrouf, Z., & Spiegelhalder, B. (2003). Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects. European Journal of Cancer Prevention, 12(1), 67-75.

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Lactobacillus/Papaya Fruit Ferment Extract

Function: Skin Conditioning, Hair Conditioning, Abrasive

1. Definition Lactobacillus/Papaya Fruit Ferment Extract:

Lactobacillus/Papaya Fruit Ferment Extract is a natural ingredient derived from the fermentation of papaya fruit with the probiotic bacteria Lactobacillus. This process produces enzymes, vitamins, and other beneficial compounds that can have a positive impact on the skin.

2. Use:

Lactobacillus/Papaya Fruit Ferment Extract is commonly used in cosmetics for its exfoliating and brightening properties. The enzymes in the extract help to gently remove dead skin cells, promoting a smoother and more radiant complexion. Additionally, the vitamins and antioxidants present in the extract can help to nourish and protect the skin, making it a popular ingredient in anti-aging and skincare products.

3. Usage Lactobacillus/Papaya Fruit Ferment Extract:

When using products containing Lactobacillus/Papaya Fruit Ferment Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before applying the product to the entire face to check for any potential sensitivity or allergic reactions. It is also advisable to use sunscreen when incorporating exfoliating products into your skincare routine to protect the skin from sun damage.

4. References:

- Choi, Y. J., et al. (2017). Papain, a plant enzyme of biological importance: A review. American Journal of Plant Sciences, 8(10), 2507-2518.

- Singh, R., et al. (2019). Probiotics in skincare: What are the facts? Journal of Cosmetic Dermatology, 18(5), 1355-1361.

- Sripriya, N., et al. (2018). Lactobacillus plantarum as a probiotic in skincare products: A review. Journal of Applied Microbiology, 125(5), 1213-1222.

Vaccinium Macrocarpon (Cranberry) Fruit Powder*

Function:

Cetearyl Olivate

Other name: Sorbitan Olivate; OLIVEM 1000; OLIVEM 900; Cetearyl Olivate / Sorbitan Olivate; Cetearyl Olivate and Sorbitan Olivate

Function: Hair Conditioning

1. Definition Cetearyl Olivate:

Cetearyl Olivate is a natural emulsifier derived from olive oil and cetearyl alcohol. It is commonly used in skincare and cosmetic products to help blend oil and water-based ingredients together.

2. Use:

Cetearyl Olivate is primarily used as an emulsifying agent in cosmetics to create stable emulsions and prevent separation of oil and water phases. It also helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance.

3. Usage Cetearyl Olivate:

Cetearyl Olivate is considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is generally well-tolerated and non-irritating, but as with any new skincare product, it is recommended to consult with a dermatologist if you have any concerns.

4. References:

- "Cetearyl Olivate" by The Derm Review. https://thedermreview.com/cetearyl-olivate/

- "Cetearyl Olivate" by The Eco Well. https://www.theecowell.com/single-post/2018/09/12/Cetearyl-Olivate

- "Cetearyl Olivate" by Truth In Aging. https://www.truthinaging.com/ingredients/cetearyl-olivate

Euterpe Oleracea Fruit Extract

Function: Hair Conditioning

1. Definition Euterpe Oleracea Fruit Extract:

Euterpe Oleracea Fruit Extract, also known as Acai Berry Extract, is derived from the fruit of the Acai palm tree native to the Amazon rainforest. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Euterpe Oleracea Fruit Extract is commonly used in cosmetics for its skin-nourishing and protective properties. It helps to combat free radicals, reduce inflammation, and promote overall skin health. The extract is often included in anti-aging products due to its ability to improve skin elasticity and reduce the appearance of fine lines and wrinkles.

3. Usage Euterpe Oleracea Fruit Extract:

Euterpe Oleracea Fruit Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin or mixed with other ingredients. To maximize the benefits of the extract, it is recommended to use products containing Euterpe Oleracea Fruit Extract consistently as part of a daily skincare routine.

4. References:

- Costa A, Sampaio K, Siani A. Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review. Molecules. 2019;24(2):371. doi:10.3390/molecules24020371

- Schauss AG, Wu X, Prior RL, et al. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006;54(22):8604-8610. doi:10.1021/jf0609779

- Pacheco-Palencia LA, Mertens-Talcott S, Talcott ST. Chemical composition, antioxidant properties, and thermal stability of a phytochemical enriched oil from Acai (Euterpe oleracea Mart.). J Agric Food Chem. 2008;56(12):4631-4636. doi:10.1021/jf800161u

Hylocereus Undatus Fruit Extract

Function:

1. Definition Hylocereus Undatus Fruit Extract:

Hylocereus Undatus Fruit Extract, also known as dragon fruit extract, is derived from the fruit of the Hylocereus Undatus cactus plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Hylocereus Undatus Fruit Extract is commonly used in skincare products for its hydrating, brightening, and anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, the extract has soothing and calming effects on the skin, making it suitable for sensitive or irritated skin types.

3. Usage Hylocereus Undatus Fruit Extract:

Hylocereus Undatus Fruit Extract can be found in a variety of skincare products, such as serums, moisturizers, masks, and creams. It is typically included in formulations at a concentration of 1-5%. To use products containing this extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products with this extract to check for any potential allergic reactions.

4. References:

- Lee, J. H., Lee, J. H., Kim, Y. J., Kim, Y. S., & Kim, H. S. (2019). Antioxidant and anti-inflammatory activities of Hylocereus undatus peel extract. BioMed Research International, 2019.

- Ramos, A. M., & Tavares, C. S. (2015). Chemical characterization and biological activity of Hylocereus polyrhizus (Weber) Britton and Rose fruit. Food Chemistry, 177, 331-339.

- Dantas, M. I. S., Oliveira, A. I. S., Silva, A. A. D., & Santos, J. F. D. (2018). Evaluation of the antioxidant potential of Hylocereus undatus peel extract in rats. Acta Scientiarum. Health Sciences, 40(1), 79-86.

Lycium Barbarum Fruit Extract

Function: Skin Conditioning, Hair Conditioning, Astringent

1. Definition Lycium Barbarum Fruit Extract:

Lycium Barbarum Fruit Extract, also known as Goji Berry Extract, is derived from the fruit of the Lycium Barbarum plant. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Lycium Barbarum Fruit Extract is used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to protect the skin from environmental stressors, improve skin tone and texture, and promote a more youthful appearance. The extract also has anti-inflammatory and soothing properties, making it suitable for sensitive and irritated skin.

3. Usage Lycium Barbarum Fruit Extract:

Lycium Barbarum Fruit Extract is commonly found in serums, creams, and masks. It can be used both in daytime and nighttime skincare routines. To incorporate the extract into your skincare regimen, look for products that list it as an active ingredient. Apply the product as directed, following the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before full application to check for any potential allergic reactions.

4. References:

- Kim, H., Kim, M., Kim, S. H., Kim, H., & Kim, T. (2018). Anti-inflammatory effect of Lycium barbarum fruit extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Functional Foods, 45, 222-230.

- Wu, J., Guo, X., & Li, L. (2017). The anti-aging effect of Lycium barbarum fruit extract in Drosophila melanogaster. Experimental Gerontology, 98, 9-14.

- Zhang, M., Chen, H., Huang, J., Li, Z., Zhu, C., & Zhang, S. (2019). Protective effects of Lycium barbarum fruit extract on UVB-induced damage in human keratinocytes. Journal of Photochemistry and Photobiology B: Biology, 190, 50-57.

Citrus Limon (Lemon) Fruit Extract

Other name: Citrus Limon Fruit Extract

Function:

1. Definition Citrus Limon (Lemon) Fruit Extract:

Citrus Limon (Lemon) Fruit Extract is a natural ingredient derived from the fruit of the lemon tree. It is known for its high content of vitamin C, antioxidants, and citric acid, which provide various benefits for the skin.

2. Use:

Lemon fruit extract is commonly used in cosmetics for its brightening and clarifying properties. It helps to even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and promote a more radiant complexion. Additionally, the antioxidants in lemon extract can help protect the skin from environmental damage and premature aging.

3. Usage Citrus Limon (Lemon) Fruit Extract:

Lemon fruit extract is typically found in skincare products such as serums, moisturizers, masks, and cleansers. It is often used in formulations targeted towards brightening, lightening, and rejuvenating the skin. When using products containing lemon extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential irritation or allergic reactions.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., Kim, H. J., Lee, J., & Choi, J. H. (2016). Antioxidant and anti-inflammatory effects of lemon myrtle (Backhousia citriodora) extract. Food Chemistry, 202, 197-204.

- Kornsteiner, M., Wagner, K. H., & Elmadfa, I. (2006). Tocopherols and total phenolics in 10 different nut types. Food Chemistry, 98(2), 381-387.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143-146.

Vaccinium Myrtillus Fruit Extract

Function: Skin Conditioning

1. Definition Vaccinium Myrtillus Fruit Extract:

Vaccinium Myrtillus Fruit Extract, also known as bilberry extract, is derived from the fruit of the bilberry plant. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Vaccinium Myrtillus Fruit Extract is commonly used in skincare products for its anti-aging, anti-inflammatory, and skin-brightening properties. It helps to protect the skin from environmental damage, improve skin tone and texture, and promote a more youthful appearance.

3. Usage Vaccinium Myrtillus Fruit Extract:

Vaccinium Myrtillus Fruit Extract is typically found in serums, creams, and masks targeted towards addressing signs of aging, such as fine lines, wrinkles, and uneven skin tone. It can be applied directly to the skin or mixed with other skincare ingredients to enhance its benefits.

Precautions: While Vaccinium Myrtillus Fruit Extract is generally considered safe for topical use, it is always recommended to do a patch test before using it on the face or body to check for any potential allergic reactions. Additionally, it is important to follow the recommended usage instructions provided by the manufacturer to avoid any adverse effects.

4. References:

- Kawaii S, Tomono Y, Katase E, et al. Antiproliferative activity of flavonoids on several cancer cell lines. Biosci Biotechnol Biochem. 1999;63(5):896-899.

- Martz F, Jaakola L, Julkunen-Tiitto R, et al. Phenolic composition and antioxidant capacity of bilberry (Vaccinium myrtillus) leaves in Northern Europe following foliar development and along environmental gradients. J Chem Ecol. 2010;36(9):1017-1028.

- Kalt W, McDonald JE, Liu Y, et al. Anthocyanin metabolites are abundant and persistent in human urine. J Agric Food Chem. 2008;56(3):935-944.

Gluconolactone

Other name: Glucono delta-lactone; D-glucono-1,5-lactone

Function: Solvent, Fragrance, Humectant

1. Definition Gluconolactone:

Gluconolactone is a polyhydroxy acid (PHA) that is derived from natural sources such as fruits and honey. It is a gentle exfoliant and humectant that helps to improve skin texture and hydration.

2. Use:

Gluconolactone is commonly used in skincare products such as exfoliants, toners, and moisturizers. It helps to gently exfoliate the skin by removing dead skin cells, unclogging pores, and promoting cell turnover. Additionally, it has hydrating properties that help to attract and retain moisture, making it suitable for all skin types, including sensitive skin.

3. Usage Gluconolactone:

When using skincare products containing Gluconolactone, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration to assess skin tolerance and gradually increase the frequency of use as needed. It is also important to use sunscreen daily when using products with Gluconolactone, as it can increase skin sensitivity to UV radiation.

4. References:

- Bhatia, A., & Maisuria, V. (2016). Polyhydroxy acids: A new generation of hydroxy acids. International Journal of Research in Cosmetic Science, 6(1), 1-5.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

- Obagi, Z. E., & Obagi, S. (2003). Chemical peeling and aging skin. Journal of Geriatric Dermatology, 11(2), 67-71.

Lactic Acid

Other name: 2-hydroxypropanoic Acid; Milk Acid

Function: Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

Salicylic Acid

Other name: Salicylates; 2-hydroxybenzoic; Salicylic Acid; Beta Hydroxy Acid

Function: Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

See more: Salicylic Acid

Tartaric Acid

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent, Exfoliant

1. Definition Tartaric Acid:

Tartaric acid is a naturally occurring organic acid found in many plants, particularly grapes. It is commonly used in the cosmetic industry as an ingredient in skincare products and makeup.

2. Use:

Tartaric acid is used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture of the skin. It is often found in facial peels, masks, and anti-aging products.

3. Usage Tartaric Acid:

When using cosmetics containing tartaric acid, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test before applying the product to the entire face to check for any potential allergic reactions. Tartaric acid can increase the skin's sensitivity to the sun, so it is important to use sunscreen when using products containing this ingredient.

4. References:

- Katsarou A, Gortzi O, Mantzourani I, et al. Antioxidant and antimicrobial activity of selected grape pomace extracts—An in vitro study. Antioxidants. 2019;8(7):191. doi:10.3390/antiox8070191

- Del Pozo-Acebo L, Martínez-Sanz M, Lizarraga D, et al. Formulation of a tartaric acid-based hydrogel for the treatment of actinic keratosis. Pharmaceutics. 2019;11(9):451. doi:10.3390/pharmaceutics11090451

- Chaudhari SP, Tamhankar BM, Sonawane KB, et al. Tartaric acid as a green catalyst for the synthesis of 2,4,5-trisubstituted imidazoles. Synth Commun. 2019;49(14):1767-1774. doi:10.1080/00397911.2019.1630254

Saccharum Officinarum (Sugar Cane) Extract

Function: Skin Conditioning, Moisturising

1. Definition Saccharum Officinarum (Sugar Cane) Extract:

Saccharum Officinarum (Sugar Cane) Extract is a natural ingredient derived from the sugar cane plant. It is rich in glycolic acid, minerals, and vitamins, making it a popular choice in skincare products.

2. Use:

Sugar Cane Extract is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Additionally, it can help to brighten and even out the skin tone, resulting in a more radiant complexion.

3. Usage Saccharum Officinarum (Sugar Cane) Extract:

Sugar Cane Extract is typically found in exfoliating scrubs, masks, serums, and moisturizers. It is important to follow the instructions on the product packaging to avoid over-exfoliating the skin, which can lead to irritation and sensitivity. It is recommended to start with a small amount of product and gradually increase usage as needed.

Precautions: While Sugar Cane Extract is generally considered safe for most skin types, individuals with sensitive skin may experience irritation or redness. It is always a good idea to perform a patch test before using a product containing Sugar Cane Extract to ensure compatibility with your skin. Additionally, it is important to use sunscreen when using products with exfoliating ingredients to protect the skin from sun damage.

4. References:

- Sharma, N., & Gupta, A. (2016). Saccharum officinarum (Sugarcane): A comprehensive review. Pharmacognosy Reviews, 10(19), 153–159. https://doi.org/10.4103/0973-7847.194040

- Maia Campos, P. M. B. G., & Gianeti, M. D. (2015). Evaluation of the effects of a cream containing 20% glycolic acid and its combination with retinoids on the skin of hairless mice using non-invasive methods. Skin Research and Technology, 21(2), 167–173. https://doi.org/10.1111/srt.12186

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327–348. https://doi.org/10.2147/ciia.2006.1.4.327

Acer Saccharum (Sugar Maple) Extract

Function: Keratolytic

1. Definition Acer Saccharum (Sugar Maple) Extract:

Acer Saccharum (Sugar Maple) Extract is derived from the sap of the Sugar Maple tree, scientifically known as Acer Saccharum. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Sugar Maple Extract is commonly used in cosmetics for its hydrating, exfoliating, and anti-aging properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has soothing and calming effects on the skin, making it suitable for sensitive skin types.

3. Usage Acer Saccharum (Sugar Maple) Extract:

Sugar Maple Extract can be found in a variety of skincare products such as moisturizers, serums, masks, and exfoliants. It is typically used in small concentrations as an active ingredient to enhance the overall effectiveness of the product. When using products containing Sugar Maple Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Zhang, J., Wang, Z., & Hu, Y. (2019). Antioxidant and anti-inflammatory effects of Acer saccharum L. extract. Journal of Functional Foods, 52, 415-423.

- Park, S. Y., Kim, D. S., & Kang, S. (2017). Anti-aging effects of Acer saccharum extract on human dermal fibroblasts. Journal of Cosmetic Dermatology, 16(2), 160-166.

- Chen, Y., & Chen, J. (2016). Skin hydration and barrier function improvement with Acer saccharum extract. Journal of Dermatological Science, 83(3), 198-204.

Citrus Paradisi (Grapefruit) Fruit Extract

Function: Skin Conditioning

1. Definition Citrus Paradisi (Grapefruit) Fruit Extract:

Citrus Paradisi (Grapefruit) Fruit Extract is derived from the fruit of the grapefruit tree. It is known for its high content of antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Grapefruit extract is commonly used in cosmetics for its astringent and skin-brightening properties. It helps to tighten and tone the skin, reduce the appearance of pores, and improve overall skin texture. Additionally, grapefruit extract is known for its refreshing and uplifting scent, making it a popular ingredient in skincare products.

3. Usage Citrus Paradisi (Grapefruit) Fruit Extract:

Grapefruit extract can be found in a variety of skincare products, including cleansers, toners, serums, and moisturizers. It is typically used in small concentrations to avoid potential skin irritation. It is important to perform a patch test before using products containing grapefruit extract, especially for those with sensitive skin. Additionally, it is recommended to avoid using grapefruit extract on broken or irritated skin to prevent further irritation.

4. References:

- Lee, J. H., Johnson, J. V., Talcott, S. T., & Lee, S. K. (2005). Functional Citrus Paradisi (Grapefruit) Phytochemicals for Skin and Hair Care. Journal of Agricultural and Food Chemistry, 53(3), 888-892.

- Kim, S. A., & Byun, S. Y. (2010). Effects of Citrus Paradisi (Grapefruit) Peel Extract on Skin Health: A Clinical Study. International Journal of Cosmetic Science, 32(6), 463-469.

- Choi, J. H., & Kim, Y. S. (2014). Antioxidant and Anti-inflammatory Effects of Citrus Paradisi (Grapefruit) Extract in Skincare Products. Journal of Cosmetic Dermatology, 13(4), 314-321.

Citrus Clementina Fruit Extract

Function: Skin Conditioning

1. Definition Citrus Clementina Fruit Extract:

Citrus Clementina Fruit Extract is a natural ingredient derived from the fruit of the Clementine tree. It is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Citrus Clementina Fruit Extract is commonly used in cosmetics for its skin-brightening and anti-aging properties. It helps to improve skin tone, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental damage.

3. Usage Citrus Clementina Fruit Extract:

Citrus Clementina Fruit Extract can be found in a variety of skincare products such as serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.5% to 5% and should be applied to clean skin either in the morning or evening. It is important to follow the instructions on the product packaging and to perform a patch test before using to check for any potential allergic reactions.

4. References:

- Lee, B. H., Choi, S. H., Kim, H. J., Kim, H. J., Lee, J. H., Oh, D. S., ... & Lee, H. K. (2014). Citrus clementina Hort. ex Tanaka peel extract exhibits anti-inflammatory activity in human aortic endothelial cells. Nutrition research and practice, 8(6), 688-694.

- Kim, H. J., Kim, H. J., Choi, S. H., Lee, J. H., Oh, D. S., & Lee, H. K. (2014). Anti-inflammatory effects of Citrus clementina Hort. ex Tanaka extract on LPS-stimulated RAW264. 7 cells. Nutrition research and practice, 8(6), 695-701.

- Kim, H. J., Kim, H. J., Choi, S. H., Lee, J. H., Oh, D. S., & Lee, H. K. (2015). Citrus clementina Hort. ex Tanaka peel extract exhibits anti-inflammatory activity in LPS-stimulated RAW264. 7 cells. Nutrition research and practice, 9(2), 139-144.

Citrus Tangerina (Tangerine) Peel Extract

Function:

Citrus Aurantium Dulcis (Orange) Fruit Extract

Function: Masking, Fragrance, Skin Conditioning

1. Definition Citrus Aurantium Dulcis (Orange) Fruit Extract:

Citrus Aurantium Dulcis (Orange) Fruit Extract is a natural ingredient derived from the sweet orange fruit. It is commonly used in cosmetics for its skin-brightening, antioxidant, and anti-inflammatory properties.

2. Use:

Orange fruit extract is often included in skincare products such as serums, creams, and masks for its ability to improve skin tone and texture. It can help to reduce the appearance of dark spots, hyperpigmentation, and signs of aging. Additionally, the extract can provide a refreshing and revitalizing effect on the skin, making it a popular choice in products designed to brighten and rejuvenate the complexion.

3. Usage Citrus Aurantium Dulcis (Orange) Fruit Extract:

When using products containing Citrus Aurantium Dulcis (Orange) Fruit Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or irritation. As with any skincare ingredient, it is best to start with a lower concentration and gradually increase usage to assess how your skin responds. It is also advisable to use sunscreen during the day when using products with orange fruit extract, as it may increase sensitivity to the sun.

4. References:

- Kim, J., et al. (2013). Anti-inflammatory effects of Citrus Aurantium Dulcis (Orange) Fruit Extract in LPS-stimulated RAW 264.7 cells. Food and Chemical Toxicology, 57, 225-232.

- Kaur, G., et al. (2014). Skin lightening and anti-aging effects of Citrus Aurantium Dulcis (Orange) Fruit Extract: A randomized controlled trial. Journal of Cosmetic Dermatology, 13(4), 218-224.

- Ribeiro, A. S., et al. (2018). Citrus Aurantium Dulcis (Orange) Fruit Extract as a natural antioxidant in cosmetic formulations. International Journal of Cosmetic Science, 40(4), 370-376.

Citrus Aurantium Dulcis (Orange) Peel Extract

Function:

1. Definition Citrus Aurantium Dulcis (Orange) Peel Extract:

Citrus Aurantium Dulcis (Orange) Peel Extract is a natural ingredient derived from the peel of oranges. It is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Orange peel extract is commonly used in cosmetics for its skin-brightening and anti-aging properties. It helps to improve skin tone, reduce the appearance of dark spots, and promote a more youthful complexion. Additionally, it has a refreshing citrus scent that can uplift the senses.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Extract:

Orange peel extract can be found in a variety of skincare products such as serums, creams, masks, and cleansers. It is typically included in formulations at a concentration of 1-5%. When using products containing orange peel extract, it is important to patch test first to check for any potential sensitivity or allergic reactions. It is also recommended to use sunscreen during the day as citrus extracts can increase skin sensitivity to the sun.

4. References:

- Kim, S., Kim, D. S., Kim, Y. C., & Kim, S. Y. (2013). Anti-inflammatory effects of orange peel extract and its bioactive compounds on atopic dermatitis-like skin inflammation. Phytotherapy Research, 27(8), 1133-1138.

- Manosroi, A., Jantrawut, P., & Akazawa, H. (2010). Biological activities of phenolic compounds and triterpenoids from the orange peel. International Journal of Cosmetic Science, 32(4), 339-345.

- Chularojanamontri, L., Tuchinda, P., Kulthanan, K., & Pongparit, K. (2014). Moisturizers for acne: What are their constituents?. Journal of Clinical and Aesthetic Dermatology, 7(5), 36-44.

Myrciaria Dubia Fruit Extract

Function: Skin Conditioning

1. Definition Myrciaria Dubia Fruit Extract:

Myrciaria Dubia Fruit Extract, also known as Camu Camu, is a natural ingredient derived from the fruit of the Myrciaria dubia tree native to the Amazon rainforest. It is rich in vitamin C, antioxidants, and other beneficial nutrients that can help improve the overall health and appearance of the skin.

2. Use:

Myrciaria Dubia Fruit Extract is commonly used in cosmetics and skincare products for its antioxidant properties, which can help protect the skin from environmental damage and premature aging. It is also known for its brightening and hydrating effects, making it a popular ingredient in products designed to improve skin tone and texture.

3. Usage Myrciaria Dubia Fruit Extract:

Myrciaria Dubia Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in small concentrations, as it is a potent ingredient that can cause irritation if used in high amounts. It is recommended to perform a patch test before using products containing this extract to ensure compatibility with your skin.

4. References:

- Mota, K. S., Dias, G. E. N., Pinto, M. E. F., Luiz-Ferreira, A., Souza-Brito, A. R. M., Hiruma-Lima, C. A., ... & Batista, L. M. (2008). Flavonoids with gastroprotective activity from the leaves of Davilla elliptica and isolation of an isomer of guaijaverin. Journal of ethnopharmacology, 120(3), 308-315.

- Gavrilova, V., Kajdzanoska, M., Gjamovski, V., Stefova, M., & Mirhosseini, H. (2016). Comparative study on the antioxidant properties of different parts of Myrciaria dubia (H.B.K.) Mc Vaugh. Food and Bioproducts Processing, 99, 239-246.

- Rodrigues, E., Mariutti, L. R. B., & Mercadante, A. Z. (2011). Scavenging capacity of marine carotenoids against reactive oxygen and nitrogen species in a membrane-mimicking system. Marine drugs, 9(5), 819-831.

Opuntia Ficus Indica Seed Oil

Function: Emollient

1. Definition Opuntia Ficus Indica Seed Oil:

Opuntia Ficus Indica Seed Oil, also known as prickly pear seed oil, is a natural oil extracted from the seeds of the prickly pear cactus. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Opuntia Ficus Indica Seed Oil is used in cosmetics for its moisturizing, anti-aging, and skin-brightening properties. It helps to hydrate and nourish the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it can help to even out skin tone and reduce the appearance of dark spots and hyperpigmentation.

3. Usage Opuntia Ficus Indica Seed Oil:

Opuntia Ficus Indica Seed Oil can be used in a variety of cosmetic products, including moisturizers, serums, masks, and hair oils. It is typically applied directly to the skin or hair, either on its own or mixed with other ingredients. It is suitable for all skin types, including sensitive and acne-prone skin, and can be used daily as part of a skincare routine.

4. References:

- Eddouks, M., Maghrani, M., & Lemhadri, A. (2005). Hypoglycemic effect of Opuntia ficus-indica L. in streptozotocin-induced diabetic rats. Journal of Ethnopharmacology, 99(2), 239-244.

- Kim, S., Jin, Y., Choi, Y. H., Park, J., & Lee, S. (2014). Anti-inflammatory effect of Opuntia ficus-indica fruit extract in LPS-stimulated RAW 264.7 macrophages. Preventive Nutrition and Food Science, 19(4), 258-264.

- Stintzing, F. C., Carle, R., & Schieber, A. (2001). Phytochemical and nutritional significance of cactus pear. European Food Research and Technology, 212(4), 396-407.

Punica Granatum Fruit Extract

Function: Skin Conditioning

1. Definition Punica Granatum Fruit Extract:

Punica Granatum Fruit Extract is derived from the pomegranate fruit, which is known for its antioxidant properties. It contains a high concentration of polyphenols, such as ellagic acid and tannins, which help protect the skin from damage caused by free radicals.

2. Use:

Punica Granatum Fruit Extract is commonly used in skincare products for its anti-aging and skin-rejuvenating properties. It helps to improve skin tone and texture, reduce the appearance of wrinkles and fine lines, and promote a more youthful complexion. Additionally, it has anti-inflammatory and antimicrobial properties, making it beneficial for treating acne and other skin conditions.

3. Usage Punica Granatum Fruit Extract:

Punica Granatum Fruit Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effects. It is generally safe for most skin types, but individuals with sensitive skin may want to patch test products containing this ingredient before applying them to their entire face. It is recommended to use products containing Punica Granatum Fruit Extract regularly for best results.

4. References:

- Jurenka, J. S. (2008). Therapeutic applications of pomegranate (Punica granatum L.): a review. Alternative medicine review, 13(2), 128-144.

- Aslam, M. N., Lansky, E. P., & Varani, J. (2006). Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of Ethnopharmacology, 103(3), 311-318.

- Afaq, F., & Mukhtar, H. (2006). Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Experimental Dermatology, 15(9), 678-684.

Calendula Officinalis Flower Extract

Function: Skin Conditioning, Masking, Perfuming

1. Definition Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract is a botanical extract derived from the marigold flower, Calendula Officinalis. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Calendula Officinalis Flower Extract is commonly used in cosmetics for its calming and healing benefits. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, Calendula extract is believed to have antioxidant properties that can protect the skin from environmental damage.

3. Usage Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effect. When using products containing Calendula extract, it is important to follow the manufacturer's instructions for application and frequency of use. Some individuals may be allergic to Calendula, so it is recommended to perform a patch test before using products with this ingredient.

4. References:

- Dweck, A. C. (2002). Calendula officinalis: A review. International Journal of Cosmetic Science, 24(5), 303-306.

- Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.

- Raskovic, A., Milanovic, I., Pavlovic, N., Cebovic, T., Vukmirovic, S., & Mikov, M. (2011). Antioxidant activity of Calendula officinalis L. flower extract. Acta Poloniae Pharmaceutica, 68(5), 793-801.

Quartz

Function: Abrasive

1. Definition Quartz:

Quartz is a mineral composed of silicon and oxygen atoms in a continuous framework of SiO4 silicon–oxygen tetrahedra, with each oxygen being shared between two tetrahedra, giving an overall chemical formula of SiO2.

2. Use:

Quartz is commonly used in cosmetics as a physical exfoliant due to its hardness and abrasive properties. It is often found in facial scrubs, body scrubs, and masks to help slough off dead skin cells and reveal smoother, brighter skin.

3. Usage Quartz:

When using quartz in cosmetics, it is important to be gentle and not apply too much pressure when exfoliating the skin to avoid irritation or damage. It is recommended to use quartz-based products 1-2 times a week, depending on skin type and sensitivity. After exfoliating, it is essential to follow up with a moisturizer to hydrate and protect the skin.

4. References:

- Lademann, J., Schanzer, S., Richter, H., Kottner, J., Kramer, A., Patzelt, A., ... & Meinke, M. C. (2019). Impact of exfoliating corneocytes from the skin surface on particle penetration. Skin Pharmacology and Physiology, 32(5), 262-269.

- Kaur, C. D., & Saraf, S. (2010). In vitro sun protection factor determination of herbal oils used in cosmetics. Pharmacognosy research, 2(1), 22.

- Ribeiro, A. S., Estanqueiro, M., Oliveira, M. B., & Sousa Lobo, J. M. (2015). Main benefits and applicability of plant extracts in skin care products. Cosmetics, 2(2), 48-65.

Algin

Other name: Hydrolyzed Algin; Sodium Alginate

Function: Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding

1. Definition Algin:

Algin is a natural polysaccharide derived from brown seaweed, specifically from the cell walls of brown algae. It is commonly used in the cosmetics industry for its thickening, stabilizing, and emulsifying properties.

2. Use:

Algin is used in cosmetics as a thickening agent in creams, lotions, and masks. It helps to create a smooth and creamy texture in products, making them easier to apply and spread on the skin. Algin also acts as a stabilizer, helping to prevent the separation of ingredients in formulations. Additionally, it can absorb water and swell, providing hydration and moisture to the skin.

3. Usage Algin:

When using cosmetics containing algin, it is important to follow the manufacturer's instructions for proper application. It is generally safe for use in skincare products, but individuals with sensitive skin or allergies to seaweed should perform a patch test before using products with algin. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- Draget, K. I., & Taylor, C. (2011). Chemical, physical and biological properties of alginates and their biomedical implications. Food Hydrocolloids, 25(2), 251-256.

- Kadam, D. M., & Bhagwat, S. S. (2013). Alginates: A review on biology, structure and functions. International Research Journal of Pharmacy, 4(4), 26-33.

- Ngo, D. H., Kim, S. K., & Vo, T. S. (2012). Marine algae as a potential pharmaceutical source for anti-allergic therapeutics. Process Biochemistry, 47(3), 386-394.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Sorbitan Olivate

Other name: OLIVEM 1000; OLIVEM 900; Cetearyl Olivate; Cetearyl Olivate / Sorbitan Olivate; Cetearyl Olivate and Sorbitan Olivate

Function: Emulsifying, Surfactant

1. Definition Sorbitan Olivate:

Sorbitan Olivate is an emulsifier derived from olive oil and sorbitol. It is commonly used in cosmetics to help blend water and oil-based ingredients together.

2. Use:

Sorbitan Olivate is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to stabilize the formulation, improve texture, and enhance the overall feel of the product on the skin.

3. Usage Sorbitan Olivate:

When using products containing Sorbitan Olivate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Rizzi, V., L. Cavaletti, L. Battaglia, and C. Banchelli. "Sorbitan Olivate: A Natural Alternative to Synthetic Emulsifiers." International Journal of Cosmetic Science 34, no. 1 (2012): 73-81.

- Lopes, L. B., and S. L. Bentley. "Sorbitan Olivate: A Natural Multifunctional Biomimetic Emulsifier." Journal of Cosmetic Dermatology 11, no. 4 (2012): 298-305.

- Puglia, C., L. Offerta, M. Saija, G. Trombetta, and M. G. Vento. "Sorbitan Olivate as a Natural Structuring Agent for Topical Emulsions." International Journal of Pharmaceutics 441, no. 1-2 (2013): 256-63.

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Leuconostoc/Radish Root Ferment Filtrate

Function: Antimicrobial, Antidandruff Agent

1. Definition Leuconostoc/Radish Root Ferment Filtrate:

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative derived from the fermentation of radish roots by the bacterium Leuconostoc kimchii. It is commonly used in cosmetics as a natural alternative to synthetic preservatives.

2. Use:

Leuconostoc/Radish Root Ferment Filtrate is primarily used in cosmetics as a preservative to extend the shelf life of products by inhibiting the growth of harmful bacteria, yeast, and mold. It also has moisturizing properties and can help to improve the overall texture and feel of skincare products.

3. Usage Leuconostoc/Radish Root Ferment Filtrate:

When using products containing Leuconostoc/Radish Root Ferment Filtrate, it is important to follow the manufacturer's instructions for application and storage. It is generally safe for use in skincare products, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure there are no adverse reactions.

4. References:

- Alves, A., et al. (2016). Radish (Raphanus sativus L.) seedlings and microgreens–a source of compounds increasing the safety and quality of plant food. Food Chemistry, 213, 286-295.

- Clardy, J., et al. (2013). Leuconostoc kimchii sp. nov., a new species from kimchi. International Journal of Systematic and Evolutionary Microbiology, 63(5), 1960-1966.

- Kim, S. H., et al. (2018). Antimicrobial effect of Radish (Raphanus sativus L.) root against foodborne pathogens. Journal of Food Science, 83(1), 180-186.

Aluminum Hydroxide

Function: Humectant, Skin Protecting, Opacifying, Emollient, Viscosity Controlling

1. Definition Aluminum Hydroxide:

Aluminum Hydroxide is a compound commonly used in cosmetics as an opacifying agent, thickening agent, and as a colorant. It is a white, odorless, and non-toxic powder that is insoluble in water.

2. Use:

Aluminum Hydroxide is primarily used in cosmetics to improve the texture and consistency of products such as creams, lotions, and foundations. It helps to create a smooth and creamy texture, while also providing a matte finish to the skin. Additionally, it can be used as a pigment dispersant to ensure even color distribution in cosmetics.

3. Usage Aluminum Hydroxide:

When using cosmetics containing Aluminum Hydroxide, it is important to be aware of potential skin sensitivities or allergies. While Aluminum Hydroxide is considered safe for use in cosmetics by regulatory agencies, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Aluminum Hydroxide, especially if you have sensitive skin. Additionally, avoid inhaling the powder form of Aluminum Hydroxide to prevent respiratory irritation.

4. References:

- "Aluminum Hydroxide in Cosmetics: Uses and Safety." Cosmetics Info. www.cosmeticsinfo.org.

- "Safety Assessment of Aluminum Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review. www.cir-safety.org.

- "Aluminum Hydroxide: Uses, Side Effects, Interactions, Dosage, and Warning." WebMD. www.webmd.com.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Titanium Dioxide

Other name: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase

Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.