Bumetrizole

1. Definition Bumetrizole:

Bumetrizole, also known as 4-tert-butyl-4'-methoxydibenzoylmethane, is a chemical compound commonly used in sunscreens and other cosmetic products as a UV filter. It belongs to the class of organic compounds known as benzophenones, which are known for their ability to absorb and dissipate UV radiation.

2. Use:

Bumetrizole is primarily used in sunscreen formulations to provide protection against both UVA and UVB rays. It works by absorbing UV radiation and converting it into less harmful forms of energy, thus preventing damage to the skin. In addition to its sun-protective properties, bumetrizole is also used in some cosmetic products to prevent color fading and degradation caused by exposure to sunlight.

3. Usage Bumetrizole:

When using cosmetics containing bumetrizole, it is important to follow the instructions provided on the product packaging. Apply sunscreen with bumetrizole generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is recommended to use products with bumetrizole in conjunction with other sun protection measures, such as wearing protective clothing and seeking shade during peak sun hours.

Precautions: While bumetrizole is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing bumetrizole, especially if you have sensitive skin or a history of skin reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267.

- Draelos ZD. Sunscreens: An overview and update. J Am Acad Dermatol. 2019;80(1):266-275.

- Chatelain E, Gabard B. Photostabilization of butyl methoxydibenzoylmethane (avobenzone) and ethylhexyl methoxycinnamate by bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a new UV broadband filter. Photochem Photobiol. 2001;74(3):401-406.