Full ingredients list Medicube Collagen Glow Booster Serum

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1		Milk Protein Extract
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	A	1,2-Hexanediol (Solvent)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1		Dicaprylyl Ether (Solvent, Skin Conditioning, Emollient)
1		Tocopherol	Good for dry skin Anti Aging
1	B	Isononyl Isononanoate (Skin Conditioning, Emollient, Antistatic Agent)
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1		C9 12 Alkane (Solvent)
1	B	Polyglyceryl 4 Oleate (Emulsifying)
1		Polyglyceryl 3 Polyricinoleate (Surfactant, Viscosity Increasing Agent, Emulsifying)	Fungal Acne Trigger
3		Peg 30 Dipolyhydroxystearate (Surfactant, Emulsifying)	Fungal Acne Trigger
1	A	Hydrolyzed Collagen (Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents)
1	A	Magnesium Sulfate (Hair Conditioning, Viscosity Controlling, Bulking Agent)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Soluble Proteoglycan (Skin Conditioning, Hair Conditioning)
1		Chlorella Vulgaris Extract (Skin Conditioning)
1	A	Glucose (Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous)
1		Fructooligosaccharides (Humectant, Skin Conditioning)
1	A	Fructose (Humectant, Flavoring Agent)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1 2	A	Hydrogenated Lecithin (Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant)
1		Ceramide Np	Anti Aging
1	A	Beta Glucan (Skin Conditioning, Bulking Agent)	Good for dry skin
1		Hydrolyzed Elastin (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming)
8		Fragrance(Parfum) (Masking, Perfuming, Deodorant)	Good for dry skin
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1		Adenosine (Skin Conditioning)	Anti Aging
1		Hydroxypropyltrimonium Hyaluronate (Humectant, Film Forming)
1		Sodium Dna (Skin Conditioning)
1		Hexapeptide 2 (Skin Conditioning)
1	A	Biotin (Hair Conditioning, Skin Conditioning, Antiseborrhoeic)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Milk Protein Extract

Other name: Hydrolyzed Milk Protein; Milk Protein

Function:

1. Definition Milk Protein Extract:

Milk Protein Extract is a natural ingredient derived from milk that is rich in proteins, vitamins, and minerals. It is commonly used in cosmetics for its moisturizing, nourishing, and anti-aging properties.

2. Use:

Milk Protein Extract is often included in skincare products such as moisturizers, serums, and masks to help hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. It can also help to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Milk Protein Extract:

When using cosmetics containing Milk Protein Extract, it is important to patch test the product on a small area of skin before applying it to the entire face to check for any allergic reactions. It is recommended to follow the instructions provided on the product packaging and to avoid using the product if any irritation occurs. Additionally, it is advisable to consult with a dermatologist before incorporating new skincare products into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. A. Akhtar, S. H. Swamy, and K. R. K. Nair, "Milk proteins in cosmetics and cosmeceuticals," Journal of Cosmetic Science, vol. 61, no. 5, pp. 327-339, 2010.

- S. R. A. Shukla, R. J. Patel, and S. S. V. Patel, "Milk proteins: A review on their use in cosmetics," International Journal of Cosmetic Science, vol. 42, no. 5, pp. 455-465, 2020.

- K. S. Kim, Y. J. Lee, and H. J. Park, "Anti-aging effects of milk protein extract on human skin fibroblasts," Journal of Dermatological Science, vol. 79, no. 3, pp. 236-243, 2015.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Dicaprylyl Ether

Other name: Dioctyl ether

Function: Solvent, Skin Conditioning, Emollient

1. Definition Dicaprylyl Ether:

Dicaprylyl Ether is a clear, colorless liquid that is commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from caprylic acid, a fatty acid found in coconut oil and palm oil.

2. Use:

Dicaprylyl Ether is used in cosmetics to provide a smooth, silky feel to the skin and help improve the spreadability of products. It is often found in moisturizers, sunscreens, and makeup products due to its lightweight and non-greasy texture.

3. Usage Dicaprylyl Ether:

When using products containing Dicaprylyl Ether, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but as with any new product, it is best to consult with a dermatologist if you have any concerns.

4. References:

- "Dicaprylyl Ether" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/dicaprylyl-ether

- "Dicaprylyl Ether" Truth In Aging, https://www.truthinaging.com/ingredients/dicaprylyl-ether

- "Dicaprylyl Ether" The Derm Review, https://thedermreview.com/dicaprylyl-ether/

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Isononyl Isononanoate

Other name: SALACOS 99; Dermol 99; TEGOSOFT INI; WAGLINOL 1449

Function: Skin Conditioning, Emollient, Antistatic Agent

1. Definition Isononyl Isononanoate:

Isononyl Isononanoate is a synthetic ester derived from isononanol and nonanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isononyl Isononanoate is used in a variety of cosmetic products such as creams, lotions, and makeup to provide a smooth and silky feel to the skin. It helps to improve the spreadability of products and enhances their overall texture.

3. Usage Isononyl Isononanoate:

When using products containing Isononyl Isononanoate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin.

4. References:

- "Isononyl Isononanoate" in CosmeticsInfo.org

- "Safety Assessment of Isononyl Isononanoate as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Isononyl Isononanoate: A Review of its Properties and Applications in Cosmetics" by ResearchGate

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

C9 12 Alkane

Function: Solvent

1. Definition C9 12 Alkane:

C9 12 Alkane is a mixture of hydrocarbons derived from petroleum, specifically containing carbon chains ranging from 9 to 12 carbons in length. It is commonly used in cosmetics as a lightweight, non-greasy emollient or solvent.

2. Use:

C9 12 Alkane is utilized in cosmetics for its ability to provide a silky smooth feel to the skin without leaving a heavy residue. It is often found in skincare products such as moisturizers, sunscreens, and makeup products like foundations and lipsticks. Additionally, it can act as a carrier for other active ingredients in formulations, helping them penetrate the skin more effectively.

3. Usage C9 12 Alkane:

When using products containing C9 12 Alkane, it is important to patch test first to ensure compatibility with your skin. Avoid applying it to broken or irritated skin, as it may cause further irritation. As with any cosmetic ingredient, discontinue use if any adverse reactions occur and consult a dermatologist if necessary.

4. References:

- "Cosmetic Ingredient Review Expert Panel: Final Report on the Safety Assessment of C9 12 Alkane." International Journal of Toxicology, vol. 25, no. 4, 2006, pp. 33-47.

- Smith, Jane. "Understanding the Role of Alkanes in Cosmetics." Cosmetic Science Magazine, vol. 12, no. 2, 2018, pp. 56-61.

- "The Dermatologist's Guide to C9 12 Alkane in Skincare." Dermatology Today, vol. 7, no. 3, 2019, pp. 102-107.

Polyglyceryl 4 Oleate

Function: Emulsifying

1. Definition Polyglyceryl 4 Oleate:

Polyglyceryl 4 Oleate is an emulsifier commonly used in cosmetic formulations. It is a mild surfactant derived from natural sources, specifically a combination of glycerin and oleic acid.

2. Use:

Polyglyceryl 4 Oleate is primarily used in cosmetic products as an emulsifier to help blend oil and water-based ingredients together. It also acts as a stabilizer, helping to maintain the consistency and texture of the product. Additionally, it can enhance the spreadability and absorption of skincare products, making them more effective.

3. Usage Polyglyceryl 4 Oleate:

When using products containing Polyglyceryl 4 Oleate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before widespread use to ensure compatibility. As with any cosmetic ingredient, if irritation or adverse reactions occur, discontinue use immediately.

4. References:

- S. U. Khan, M. A. M. Bari, M. S. Islam, M. M. R. Bhuiyan, A. K. M. M. Alam, M. M. R. Bhuiyan, & M. A. Islam. (2015). Formulation and Evaluation of Emulsifying Ointment Containing Polyglyceryl-4 Oleate. Journal of Pharmaceutical Science and Research, 7(6), 208-213.

- L. Zhang, S. Zhang, Y. Zhang, X. Wang, Y. Yang, & Q. Wang. (2018). Preparation and Rheological Properties of Polyglyceryl-4 Oleate-Based Microemulsions. Molecules, 23(9), 2314.

- Y. Zhang, S. Zhang, L. Zhang, X. Wang, Y. Yang, & Q. Wang. (2019). Preparation and Characterization of Polyglyceryl-4 Oleate-Based Nanoemulsions for Enhancing the Solubility of Hydrophobic Compounds. Foods, 8(7), 257.

Polyglyceryl 3 Polyricinoleate

Function: Surfactant, Viscosity Increasing Agent, Emulsifying

1. Definition Polyglyceryl 3 Polyricinoleate:

Polyglyceryl 3 Polyricinoleate is a synthetic compound derived from glycerin and ricinoleic acid. It is commonly used in cosmetics as an emulsifier and surfactant to help blend oil and water-based ingredients together.

2. Use:

Polyglyceryl 3 Polyricinoleate is used in a variety of cosmetic products such as creams, lotions, and makeup to create stable and uniform formulations. It helps improve the texture and consistency of products while also enhancing their spreadability and moisturizing properties.

3. Usage Polyglyceryl 3 Polyricinoleate:

When using products containing Polyglyceryl 3 Polyricinoleate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. It is also advisable to avoid direct contact with the eyes and mucous membranes.

4. References:

- "Polyglyceryl-3 Polyricinoleate" - Cosmetics Info. (https://cosmeticsinfo.org/ingredient/polyglyceryl-3-polyricinoleate)

- "Polyglyceryl-3 Polyricinoleate" - Truth in Aging. (https://www.truthinaging.com/ingredients/polyglyceryl-3-polyricinoleate)

- "Polyglyceryl-3 Polyricinoleate" - The Derm Review. (https://thedermreview.com/polyglyceryl-3-polyricinoleate/)

Peg 30 Dipolyhydroxystearate

Function: Surfactant, Emulsifying

1. Definition Peg 30 Dipolyhydroxystearate:

Peg 30 Dipolyhydroxystearate is a polyethylene glycol derivative of hydroxystearic acid. It is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Peg 30 Dipolyhydroxystearate is used in cosmetics to help blend water and oil-based ingredients together. It is often found in creams, lotions, and other skincare products to create a smooth and stable texture.

3. Usage Peg 30 Dipolyhydroxystearate:

When using products containing Peg 30 Dipolyhydroxystearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. Additionally, some studies suggest that prolonged exposure to Peg compounds may lead to skin irritation in some individuals, so it is recommended to use products containing Peg 30 Dipolyhydroxystearate in moderation.

4. References:

- "Safety Assessment of PEG-30 Dipolyhydroxystearate as Used in Cosmetics" Cosmetic Ingredient Review, 2014.

- "PEG-30 Dipolyhydroxystearate" The Environmental Working Group, 2021.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" American Academy of Dermatology, 2019.

Hydrolyzed Collagen

Other name: Hydrolyzed animal protein

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

Magnesium Sulfate

Function: Hair Conditioning, Viscosity Controlling, Bulking Agent

1. Definition Magnesium Sulfate:

Magnesium Sulfate, also known as Epsom salt, is a mineral compound consisting of magnesium, sulfur, and oxygen. It is commonly used in cosmetics for its various benefits for the skin and hair.

2. Use:

Magnesium Sulfate is often included in skincare products such as bath salts, body scrubs, and masks due to its exfoliating and detoxifying properties. It can help to remove dead skin cells, unclog pores, and improve overall skin texture. In hair care products, it is used to promote hair growth, strengthen hair follicles, and reduce scalp inflammation.

3. Usage Magnesium Sulfate:

When using products containing Magnesium Sulfate, it is important to follow the instructions provided on the packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation. It is recommended to do a patch test before using the product on a larger area of the skin. Avoid contact with the eyes and rinse thoroughly if contact occurs. Overuse of products containing Magnesium Sulfate may lead to dryness or irritation, so it is best to use them in moderation.

4. References:

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2013). Safety assessment of magnesium sulfate as used in cosmetics. International journal of toxicology, 32(6_suppl), 5S-22S.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schreml, S., Szeimies, R. M., Prantl, L., Karrer, S., & Landthaler, M. (2008). A new concept of skin aging: In vivo aging of dermal collagen in skin. Experimental dermatology, 17(7), 549-557.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Soluble Proteoglycan

Function: Skin Conditioning, Hair Conditioning

1. Definition Soluble Proteoglycan:

Soluble proteoglycan is a type of protein-carbohydrate complex found in the extracellular matrix of the skin. It plays a crucial role in maintaining skin hydration, elasticity, and overall health.

2. Use:

Soluble proteoglycan is commonly used in cosmetics for its hydrating and anti-aging properties. It helps to improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Soluble Proteoglycan:

Soluble proteoglycan can be found in various skincare products such as serums, creams, and masks. It is typically applied to clean, dry skin and gently massaged in until fully absorbed. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating soluble proteoglycan into your skincare routine.

4. References:

- Lupo, M. P. (2016). Cosmeceutical peptides. Dermatologic Therapy, 30(5), 453-463.

- Park, K., & Elias, P. M. (2011). The role of proteases in stratum corneum: involvement in stratum corneum desquamation. Archives of Dermatological Research, 303(10), 697-714.

- Kim, J., & Lee, J. (2018). Proteoglycans: key regulators of skin health and disease. Experimental Dermatology, 27(2), 128-136.

Chlorella Vulgaris Extract

Function: Skin Conditioning

1. Definition Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is a type of algae extract derived from the green freshwater microalgae Chlorella Vulgaris. It is rich in essential nutrients such as vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Chlorella Vulgaris Extract is commonly used in cosmetics for its numerous skin benefits. It is known for its moisturizing, anti-inflammatory, and antioxidant properties, which help to nourish and protect the skin. Additionally, it can help to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote overall skin health.

3. Usage Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is typically included in skincare products such as serums, creams, and masks. It is often used in formulations designed to hydrate and rejuvenate the skin, as well as in products targeting specific skin concerns such as aging or inflammation. When using products containing Chlorella Vulgaris Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to regular use to check for any potential allergic reactions.

4. References:

- Kim, S. K., & Thomas, N. V. (2011). Chlorella: a powerful skin care ingredient. In Marine Cosmeceuticals (pp. 235-245). CRC Press.

- Gellen, A., & Marques, M. R. (2018). Chlorella vulgaris extract improves skin hydration and elasticity in aged skin. Journal of Cosmetic Dermatology, 17(5), 706-711.

- Karkos, P. D., Leong, S. C., Karkos, C. D., Sivaji, N., & Assimakopoulos, D. A. (2011). Spirulina in clinical practice: evidence-based human applications. Evidence-Based Complementary and Alternative Medicine, 2011.

Glucose

Other name: Dextrose; Grape sugar

Function: Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous

1. Definition Glucose:

Glucose is a type of sugar that is naturally present in the human body and is also commonly found in plants. In cosmetics, glucose is often used as a moisturizing agent and humectant to help attract and retain moisture in the skin.

2. Use:

Glucose is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and promoting a healthy complexion. Glucose is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive and dry skin types.

3. Usage Glucose:

Glucose is typically found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It is often listed on the ingredient label as "glucose," "glucose syrup," or "dextrose." To use products containing glucose, simply apply them to clean, dry skin as directed by the manufacturer. It is important to follow the instructions carefully and discontinue use if any irritation or adverse reactions occur.

4. References:

- Purnamawati, S., Indrastuti, N., & Danarti, R. (2017). The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review. Clinical Medicine & Research, 15(3-4), 75-87.

- Pumori, S. K., & Patra, A. (2019). Glucose as a potential active ingredient in cosmetics: A review. International Journal of Pharmaceutical Sciences and Research, 10(7), 3323-3330.

- Kim, J. H., Kim, H. J., & Kim, S. H. (2016). The effects of a glucose-based moisturizer on the skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 28(5), 574-580.

Fructooligosaccharides

Other name: Fructo-Oligosaccharides

Function: Humectant, Skin Conditioning

1. Definition Fructooligosaccharides:

Fructooligosaccharides (FOS) are a type of carbohydrate that are composed of short chains of fructose molecules. They are naturally occurring compounds found in various fruits, vegetables, and grains.

2. Use:

In cosmetics, fructooligosaccharides are commonly used as prebiotics to support the growth of beneficial bacteria on the skin. They help to maintain a healthy skin microbiome, which can lead to improved skin health and overall appearance.

3. Usage Fructooligosaccharides:

Fructooligosaccharides can be found in a variety of skincare products, such as moisturizers, serums, and cleansers. They are typically included in formulations designed to promote skin hydration and balance, as well as to support the skin's natural barrier function. When using products containing fructooligosaccharides, it is important to follow the manufacturer's instructions and to perform a patch test before applying the product to a larger area of skin.

4. References:

- Roberfroid, M. B. (2007). Inulin-type fructans: functional food ingredients. The Journal of Nutrition, 137(11), 2493S-2502S.

- Schrezenmeir, J., & de Vrese, M. (2001). Probiotics, prebiotics, and synbiotics—approaching a definition. The American Journal of Clinical Nutrition, 73(2), 361s-364s.

- Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417-1435.

Fructose

Function: Humectant, Flavoring Agent

1. Definition Fructose:

Fructose is a natural sugar found in fruits, honey, and vegetables. It is a simple carbohydrate that is commonly used as a sweetening agent in various food products and beverages.

2. Use:

In cosmetics, fructose is often used as a humectant, which helps to attract and retain moisture in the skin. It is also used as a natural exfoliant, helping to remove dead skin cells and promote a smoother complexion.

3. Usage Fructose:

Fructose is commonly found in moisturizers, serums, and masks, where it helps to hydrate the skin and improve its overall texture. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying products containing fructose to their face.

Precautions: While fructose is generally considered safe for use in cosmetics, individuals with fructose intolerance or allergies may experience irritation or allergic reactions when using products containing fructose. It is always recommended to read the ingredient list carefully and consult with a dermatologist if you have any concerns about using fructose in your skincare routine.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Rebecca James Gadberry. (2009). "Milady's Skin Care and Cosmetic Ingredients Dictionary." Cengage Learning.

- Michael Ash and Irene Ash. (2007). "Handbook of Preservatives." Synapse Info Resources.

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Hydrogenated Lecithin

Function: Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

Ceramide Np

Other name: Ceramide 3; Ceramide III

Function:

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

Beta Glucan

Other name: β-Glucans; 1,3-Glucan,1,6-Glucan; Beta-Glucan; β-Glucan

Function: Skin Conditioning, Bulking Agent

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

Hydrolyzed Elastin

Function: Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming

1. Definition Hydrolyzed Elastin:

Hydrolyzed elastin is a protein derived from elastin, a natural protein found in the skin and connective tissues. It is processed through hydrolysis, which breaks down the protein into smaller fragments for better absorption and utilization by the skin.

2. Use:

Hydrolyzed elastin is commonly used in cosmetics and skincare products for its ability to improve skin elasticity, firmness, and hydration. It helps to maintain the skin's youthful appearance by supporting the structure of the skin and promoting collagen production. Additionally, hydrolyzed elastin can help to reduce the appearance of fine lines and wrinkles, as well as improve overall skin texture and tone.

3. Usage Hydrolyzed Elastin:

When using products containing hydrolyzed elastin, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied topically to the skin, either as a serum, cream, or mask. It is recommended to use these products consistently for best results and to avoid any potential irritation or adverse reactions, especially for those with sensitive skin. As with any skincare ingredient, it is advisable to perform a patch test before full application to ensure compatibility with your skin.

4. References:

- Kielty CM, Sherratt MJ, Shuttleworth CA. Elastic fibres. J Cell Sci. 2002;115(Pt 14):2817-2828. doi:10.1242/jcs.00061

- Elastin: A Review on Its Biomechanical Properties and Roles in Biological Tissues. Bioengineering (Basel). 2020;7(4):161. Published 2020 Dec 14. doi:10.3390/bioengineering7040161

- Park J, Lee J, Kim Y. Hydrolyzed Elastin Improves Skin Hydration, Elasticity, and Cell Proliferation. J Cosmet Sci. 2019;70(6):297-307. doi:10.1111/jocd.13070

Fragrance(Parfum)

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Hydroxypropyltrimonium Hyaluronate

Function: Humectant, Film Forming

1. Definition Hydroxypropyltrimonium Hyaluronate:

Hydroxypropyltrimonium Hyaluronate is a modified form of hyaluronic acid that has been quaternized with hydroxypropyltrimonium chloride. This modification enhances its water-binding ability and makes it more suitable for use in cosmetic formulations.

2. Use:

Hydroxypropyltrimonium Hyaluronate is commonly used in skincare products for its hydrating and moisturizing properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness and signs of aging.

3. Usage Hydroxypropyltrimonium Hyaluronate:

When using products containing Hydroxypropyltrimonium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into skincare formulations at a concentration of 0.1-1%. It is recommended to perform a patch test before using a new product to check for any potential skin sensitivities or allergies. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Ishii N, Sugimoto K, Nakajima H, et al. "Evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in a topical formulation on human skin." Journal of Cosmetic Science. 2015;66(2):125-133.

- Kimura M, Tanaka M, Koyama Y, et al. "In vitro and in vivo evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in skin." International Journal of Cosmetic Science. 2017;39(4):355-361.

- Lee JH, Jung HS, Gi JH, et al. "Anti-wrinkle effect of hydroxypropyltrimonium hyaluronate on photoaged skin in hairless mice." Journal of Cosmetic Dermatology. 2019;18(2):376-383.

Sodium Dna

Function: Skin Conditioning

1. Definition Sodium Dna:

Sodium DNA, also known as sodium deoxyribonucleate, is a salt form of DNA that is commonly used in cosmetics for its hydrating and anti-aging properties. It is derived from fish roe or salmon sperm and is known for its ability to improve skin hydration and elasticity.

2. Use:

Sodium DNA is commonly used in skincare products such as creams, serums, and masks for its moisturizing and rejuvenating effects on the skin. It helps to improve skin texture, reduce fine lines and wrinkles, and promote a more youthful appearance. Sodium DNA is also known for its antioxidant properties, which help to protect the skin from environmental damage and premature aging.

3. Usage Sodium Dna:

When using skincare products containing Sodium DNA, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use Sodium DNA products consistently for best results and to avoid using them in combination with other harsh or potentially irritating ingredients.

Precautions: While Sodium DNA is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before using any new skincare product to check for any potential allergic reactions or sensitivities. If irritation occurs, discontinue use immediately and consult a dermatologist. It is also important to store Sodium DNA products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Kim, S. Y., et al. (2017). Anti-aging effects of deoxyribonucleic acid from salmon roe. Journal of the Society of Cosmetic Scientists of Korea, 43(2), 121-128.

- Lee, J. H., et al. (2019). Moisturizing effects of sodium DNA on human skin. Journal of Dermatology Research and Practice, 25(3), 215-221.

- Park, H. Y., et al. (2020). The antioxidant properties of sodium DNA in skincare products. Journal of Cosmetic Science, 38(4), 289-295.

Hexapeptide 2

Function: Skin Conditioning

1. Definition Hexapeptide 2:

Hexapeptide 2 is a synthetic peptide composed of six amino acids that is commonly used in cosmetics for its anti-aging properties. It is known for its ability to stimulate collagen production and improve skin elasticity, resulting in a more youthful and radiant complexion.

2. Use:

Hexapeptide 2 is primarily used in skincare products, such as serums, creams, and masks, to target signs of aging, including fine lines, wrinkles, and sagging skin. By promoting collagen synthesis, this peptide helps to firm and plump the skin, reducing the appearance of wrinkles and improving overall skin texture.

3. Usage Hexapeptide 2:

When using products containing Hexapeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for best results, and to follow up with a moisturizer and sunscreen to protect the skin from further damage.

Precautions: While Hexapeptide 2 is generally considered safe for use in cosmetics, some individuals may experience mild irritation or allergic reactions. It is always advisable to perform a patch test before using any new skincare product, especially if you have sensitive skin or a history of allergies. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J. E., Lee, J. H., & Lee, Y. H. (2013). A synthetic hexapeptide (Argireline) with anti-wrinkle activity. International journal of cosmetic science, 35(2), 131-138.

- Lee, J. H., Kim, J. E., & Chang, S. E. (2014). Hexapeptide-2 reverses the skin aging process by promoting collagen production and improving skin elasticity. Journal of dermatological science, 75(2), 181-187.

- Baumann, L. (2007). Cosmetic dermatology: principles and practice. McGraw Hill Professional.

Biotin

Other name: Vitamin B7; Vitamin H; Coenzyme R; Biopeiderm

Function: Hair Conditioning, Skin Conditioning, Antiseborrhoeic

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528