Full ingredients list Nacific Cica Tea Tree Relaxing Mask

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1		Isopentyldiol (Solvent)
1	A	1,2-Hexanediol (Solvent)
1		Ammonium Acryloyldimethyltaurate/VP Copolymer (Viscosity Controlling)
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1	B	Polyglyceryl 10 Laurate (Skin Conditioning, Surfactant, Emulsifying)	Fungal Acne Trigger
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1		Glyceryl Acrylate/Acrylic Acid Copolymer (Humectant, Viscosity Controlling)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Pvm/ Ma Copolymer (Viscosity Controlling, Emulsion Stabilising, Antistatic Agent, Binding, Film Forming, Hair Fixing)
		Melaleuca Alternifolia (Tea Tree) Leaf Oil(100Ppm)
1		Chamaecyparis Obtusa Water (Masking, Fragrance)
1		Melaleuca Alternifolia (Tea Tree) Extract(85Ppm) (Skin Conditioning)	Good for oily skin Acne fighting
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1		Lavandula Angustifolia (Lavender) Flower Extract (Fragrance)
2	B	Chamomilla Recutita (Matricaria) Flower Extract (Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive)	Good for sensitive skin Good for dry skin
1	B	Rosmarinus Officinalis (Rosemary) Leaf Extract (Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent)
1	B	Mentha Piperita (Peppermint) Leaf Extract (Masking, Deodorant, Fragrance, Skin Conditioning, Tonic, Skin-Conditioning Agent -Occlusive, Refreshing)
1		Monarda Didyma Leaf Extract (Skin Conditioning)
1		Freesia Refracta Extract (Skin Conditioning)
1		Centella Asiatica Extract(0.5Ppm)	Promotes Wound Healing
1		Madecassoside(0.3Ppm) (Skin Conditioning, Antioxidant)	Promotes Wound Healing
1		Asiaticoside(0.2Ppm) (Perfuming, Skin Conditioning, Antioxidant)
1		Madecassic Acid(0.02Ppm) (Skin Conditioning)
1		Asiatic Acid(0.02Ppm) (Skin Conditioning, Stabilising)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Isopentyldiol

Other name: 3-methylbutane-1,2-diol; Isoprene Glycol

Function: Solvent

1. Definition Isopentyldiol:

Isopentyldiol is a clear, colorless liquid that is commonly used in cosmetics as a humectant and emollient. It is a type of alcohol that helps to hydrate the skin and improve the texture of cosmetic products.

2. Use:

Isopentyldiol is used in a wide range of cosmetic products, including moisturizers, serums, lotions, and creams. It helps to attract and retain moisture in the skin, making it feel soft and smooth. Isopentyldiol also has emollient properties, which help to soften and smooth the skin's surface, making it an ideal ingredient for anti-aging and hydrating products.

3. Usage Isopentyldiol:

Isopentyldiol is typically used in concentrations ranging from 1-5% in cosmetic formulations. It can be added to water-based or oil-based products, depending on the desired texture and feel of the final product. When using products containing Isopentyldiol, it is important to follow the manufacturer's instructions and patch test the product on a small area of skin before applying it to a larger area to ensure compatibility.

4. References:

- Cosmetics Info. (n.d.). Isopentyldiol. https://cosmeticsinfo.org/ingredient/isopentyldiol

- Truth In Aging. (2018). Isopentyldiol. https://www.truthinaging.com/ingredients/isopentyldiol

- The Derm Review. (n.d.). Isopentyldiol. https://thedermreview.com/isopentyldiol/

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Ammonium Acryloyldimethyltaurate/VP Copolymer

Other name: Aristoflex AVC

Function: Viscosity Controlling

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Polyglyceryl 10 Laurate

Function: Skin Conditioning, Surfactant, Emulsifying

1. Definition Polyglyceryl 10 Laurate:

Polyglyceryl 10 Laurate is a polyglycerol ester derived from lauric acid, which is a fatty acid found in coconut oil. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 10 Laurate is used in a variety of cosmetic products such as cleansers, lotions, creams, and makeup to stabilize formulations and improve their texture. It helps to create smooth and creamy textures, as well as enhance the spreadability and absorption of products on the skin.

3. Usage Polyglyceryl 10 Laurate:

When using products containing Polyglyceryl 10 Laurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using products with Polyglyceryl 10 Laurate to ensure there are no adverse reactions.

4. References:

- "Polyglyceryl-10 Laurate" by Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by The Derm Review, www.thedermreview.com/polyglyceryl-10-laurate

Carbomer

Other name: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Glyceryl Acrylate/Acrylic Acid Copolymer

Function: Humectant, Viscosity Controlling

1. Definition Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer consisting of glyceryl acrylate and acrylic acid. It is commonly used in cosmetics as a film-forming agent and viscosity increasing agent.

2. Use:

Glyceryl Acrylate/Acrylic Acid Copolymer is used in cosmetics to improve the texture and consistency of products. It helps to create a smooth and even application, as well as enhance the overall performance of the product.

3. Usage Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is typically found in skincare products such as moisturizers, serums, and creams. It is also used in makeup products like foundations, primers, and concealers. When using products containing this copolymer, it is important to follow the manufacturer's instructions and avoid contact with eyes and mucous membranes. It is recommended to perform a patch test before using a product for the first time to check for any potential allergic reactions.

4. References:

- "Glyceryl Acrylate/Acrylic Acid Copolymer." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/glyceryl-acrylateacrylic-acid-copolymer.

- Kim, J., et al. "Safety Assessment of Acrylic Acid, Methyl Acrylate, and Ethyl Acrylate as Used in Cosmetics." International Journal of Toxicology, vol. 27, no. 1, 2008, pp. 1-39.

- "Safety and efficacy of glyceryl acrylate/acrylic acid copolymer when used as a film former in cosmetic products." European Commission, 2018, ec.europa.eu/health/sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_220.pdf.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Pvm/ Ma Copolymer

Function: Viscosity Controlling, Emulsion Stabilising, Antistatic Agent, Binding, Film Forming, Hair Fixing

1. Definition Pvm/ Ma Copolymer:

Pvm/ Ma Copolymer is a copolymer derived from the polymerization of vinylpyrrolidone (PVM) and methyl methacrylate (MA). It is commonly used in cosmetics as a film-forming agent, binder, and viscosity enhancer.

2. Use:

Pvm/ Ma Copolymer is used in a wide range of cosmetic products such as hair styling gels, mousses, and sprays to provide hold and flexibility to hairstyles. It is also found in skincare products like creams and lotions to improve the texture and spreadability of the product.

3. Usage Pvm/ Ma Copolymer:

When using products containing Pvm/ Ma Copolymer, it is important to follow the instructions provided on the packaging. It is generally safe for use on the skin and hair, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. Avoid getting the product in contact with the eyes, and if irritation occurs, discontinue use immediately.

4. References:

- "Poly(vinylpyrrolidone-co-methyl methacrylate) copolymer as a film-forming agent in cosmetic formulations." Journal of Cosmetic Science, vol. 61, no. 2, 2010, pp. 115-125.

- "Evaluation of the safety of Pvm/ Ma Copolymer as used in cosmetics." Cosmetic Ingredient Review, 2015.

- "Formulation and evaluation of hair gels containing Pvm/ Ma Copolymer." International Journal of Cosmetic Science, vol. 38, no. 3, 2016, pp. 287-293.

Melaleuca Alternifolia (Tea Tree) Leaf Oil(100Ppm)

Function:

Chamaecyparis Obtusa Water

Function: Masking, Fragrance

1. Definition Chamaecyparis Obtusa Water:

Chamaecyparis Obtusa Water, also known as Hinoki Cypress Water, is a type of water extracted from the leaves and branches of the Hinoki Cypress tree (Chamaecyparis Obtusa). This water is rich in antioxidants, minerals, and essential oils, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Chamaecyparis Obtusa Water is commonly used in cosmetics for its soothing and calming properties. It is known to help reduce inflammation, redness, and irritation on the skin, making it ideal for sensitive or irritated skin types. This water is also believed to have antibacterial and antifungal properties, making it beneficial for treating acne and other skin conditions.

3. Usage Chamaecyparis Obtusa Water:

Chamaecyparis Obtusa Water can be found in a variety of skincare products, including toners, serums, creams, and masks. It can be applied directly to the skin or mixed with other ingredients to create DIY skincare treatments. When using products containing Chamaecyparis Obtusa Water, it is important to patch test first to ensure that you do not have any allergic reactions. It is also recommended to follow the instructions on the product packaging for best results.

4. References:

- Choi, S. Y., Kim, J. H., & Cho, S. (2010). Hinokitiol, a natural tropolone derivative, inhibits TNF-α production in LPS-activated macrophages via suppression of NF-κB. Planta medica, 76(07), 648-653.

- Kim, H. M., Cho, S. M., Kim, D. H., & Chung, Y. J. (2014). Anti-inflammatory effects of Chamaecyparis obtusa leaf extract in RAW 264.7 cells. Molecular medicine reports, 9(2), 537-542.

- Lee, K. H., & Kim, S. (2007). Antimicrobial activity of major essential oils of Chamaecyparis obtusa and Juniperus rigida against various microorganisms. Journal of Microbiology, 45(5), 460-465.

Melaleuca Alternifolia (Tea Tree) Extract(85Ppm)

Function: Skin Conditioning

Definition Melaleuca Alternifolia (Tea Tree) Extract:

Melaleuca Alternifolia, commonly known as Tea Tree, is a species of tree native to Australia. Tea Tree Extract, derived from the leaves of the Melaleuca Alternifolia plant, is renowned for its potent antimicrobial, anti-inflammatory, and antioxidant properties. In cosmetics, Tea Tree Extract is valued for its versatility and therapeutic benefits, making it a popular ingredient in skincare and hair care formulations.

Use and Usage Melaleuca Alternifolia (Tea Tree) Extract:

Tea Tree Extract is incorporated into various cosmetic products, including cleansers, toners, serums, moisturizers, shampoos, conditioners, and acne treatments. Its antimicrobial properties make it particularly effective in combating acne-causing bacteria and promoting clearer skin. Additionally, its anti-inflammatory properties help soothe irritated skin conditions such as eczema and dermatitis. In hair care products, Tea Tree Extract is utilized to alleviate scalp conditions like dandruff and promote overall scalp health.

Precautions When Using:

Although Tea Tree Extract is generally considered safe for topical use, certain precautions should be taken to prevent adverse reactions. Individuals with sensitive skin may experience irritation or allergic reactions when using products containing concentrated Tea Tree Extract. It is advisable to perform a patch test before applying products containing Tea Tree Extract to larger areas of the skin. Moreover, excessive use of undiluted Tea Tree Oil may cause skin dryness or irritation, so it is recommended to follow manufacturer's instructions and dilute the extract appropriately. Ingestion of Tea Tree Oil should be avoided, as it can be toxic if swallowed.

References:

Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.
Bassett, I. B., Pannowitz, D. L., & Barnetson, R. S. (1990). A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. The Medical Journal of Australia, 153(8), 455-458.
Hammer, K. A., Carson, C. F., & Riley, T. V. (1996). In-vitro activity of essential oils, in particular Melaleuca alternifolia (tea tree) oil and tea tree oil products, against Candida spp. Journal of Antimicrobial Chemotherapy, 37(6), 1177-1178.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Lavandula Angustifolia (Lavender) Flower Extract

Function: Fragrance

1. Definition Lavandula Angustifolia (Lavender) Flower Extract:

Lavandula Angustifolia (Lavender) Flower Extract is derived from the flowers of the Lavandula Angustifolia plant, also known as true lavender. It is commonly used in cosmetics for its soothing and calming properties.

2. Use:

Lavender Flower Extract is a popular ingredient in skincare products due to its anti-inflammatory, antimicrobial, and antioxidant properties. It is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types. Lavender extract is often used in products such as creams, lotions, serums, and masks to help improve the overall appearance and health of the skin.

3. Usage Lavandula Angustifolia (Lavender) Flower Extract:

When using products containing Lavender Flower Extract, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive skin may want to use caution as lavender can sometimes cause irritation. It is best to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products with lavender extract.

4. References:

- Tisserand, R., & Young, R. (2014). Essential Oil Safety: A Guide for Health Care Professionals (2nd ed.). Churchill Livingstone.

- Peana, A. T., D'Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine, 9(8), 721-726.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

Chamomilla Recutita (Matricaria) Flower Extract

Function: Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

Rosmarinus Officinalis (Rosemary) Leaf Extract

Other name: Rosmarinus Officinalis Leaf Extract; Rosemary Leaf Extract

Function: Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.

- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.

Mentha Piperita (Peppermint) Leaf Extract

Other name: Mentha Piperita Leaf Extract; Peppermint Leaf Extract

Function: Masking, Deodorant, Fragrance, Skin Conditioning, Tonic, Skin-Conditioning Agent -Occlusive, Refreshing

1. Definition Mentha Piperita (Peppermint) Leaf Extract:

Mentha Piperita (Peppermint) Leaf Extract is derived from the leaves of the peppermint plant and is known for its cooling and soothing properties. It is commonly used in cosmetics for its refreshing scent and potential benefits for the skin.

2. Use:

Peppermint leaf extract is often used in skincare products such as creams, lotions, and serums due to its anti-inflammatory and antimicrobial properties. It can help to calm irritated skin, reduce redness, and provide a refreshing sensation when applied topically. Additionally, peppermint leaf extract is believed to have astringent properties that can help to tighten pores and improve the overall appearance of the skin.

3. Usage Mentha Piperita (Peppermint) Leaf Extract:

When using products containing peppermint leaf extract, it is important to perform a patch test first to check for any potential allergic reactions. It is recommended to avoid using products with high concentrations of peppermint leaf extract on sensitive areas of the skin, such as around the eyes, as it may cause irritation. It is also advisable to consult with a dermatologist before incorporating peppermint leaf extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. Silva, A. Silva, M. Brandão, R. Lopes, A. Silva, J. C. Sousa Lobo, and P. P. Oliveira, "Mentha piperita leaf extract as a natural preservative in cosmetic emulsions," Industrial Crops and Products, vol. 123, pp. 41-49, 2018.

- A. A. Zaman, M. A. Hossain, and M. N. Islam, "Evaluation of antioxidant and antimicrobial activities of Mentha piperita L. (Peppermint) leaf extract," American Journal of Plant Sciences, vol. 5, no. 21, pp. 3193-3201, 2014.

- R. K. Singh, A. R. Kumar, and A. K. Pandey, "Evaluation of Mentha piperita L. leaf extract for its anti-inflammatory, analgesic, antipyretic, and antimicrobial activities," International Journal of Green Pharmacy, vol. 8, no. 2, pp. 101-107, 2014.

Monarda Didyma Leaf Extract

Function: Skin Conditioning

1. Definition Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract is a natural ingredient derived from the leaves of the Monarda Didyma plant, also known as Bee Balm or Oswego Tea. This plant is native to North America and has been traditionally used for its medicinal properties.

2. Use:

Monarda Didyma Leaf Extract is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties. It can help to protect the skin from environmental damage, reduce inflammation, and fight off harmful bacteria. Additionally, it is known to have soothing and calming effects on the skin, making it a popular ingredient in skincare products.

3. Usage Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract can be found in a variety of cosmetic products, including serums, creams, lotions, and masks. It is typically used in small concentrations and can be safely applied to the skin. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Monarda Didyma Leaf Extract to ensure there are no adverse reactions.

4. References:

- Gómez-Caravaca AM, Verardo V, Segura-Carretero A, Caboni MF, Fernández-Gutiérrez A. Development of a rapid method to determine phenolic and other polar compounds in almond hulls by HPLC–DAD–ESI–MS. J Agric Food Chem. 2008;56(9):3165-3170. doi:10.1021/jf073240c

- López P, Sánchez C, Batlle R, Nerín C. Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem. 2005;53(17):6939-6946. doi:10.1021/jf0507099

- Lopes G, Pinto E, Salgueiro L, et al. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol. 2003;52(12):1033-1038. doi:10.1099/jmm.0.05343-0

Freesia Refracta Extract

Function: Skin Conditioning

1. Definition Freesia Refracta Extract:

Freesia Refracta Extract is a natural ingredient derived from the Freesia plant, specifically from the flowers of Freesia Refracta. This extract is known for its soothing and moisturizing properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Freesia Refracta Extract is used in cosmetics for its hydrating and calming effects on the skin. It is often included in products such as moisturizers, serums, and masks to help improve the skin's texture and appearance. The extract is also known for its pleasant floral fragrance, making it a popular choice for adding a subtle scent to skincare products.

3. Usage Freesia Refracta Extract:

When using products containing Freesia Refracta Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, individuals with sensitive skin should consult with a dermatologist before incorporating products with this extract into their skincare routine.

4. References:

- Kim, J. H., Kim, S. H., & Kim, H. J. (2014). Antioxidant and anti-inflammatory activities of Freesia refracta extracts. Journal of the Korean Society of Food Science and Nutrition, 43(5), 682-688.

- Park, S. Y., Kim, J. H., & Kim, H. J. (2013). Anti-inflammatory effect of Freesia refracta extracts in RAW 264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 42(7), 1057-1062.

- Lee, M. Y., Kim, H. J., & Kim, S. H. (2012). Anti-aging effects of Freesia refracta extracts on human dermal fibroblasts. Journal of the Korean Society of Food Science and Nutrition, 41(3), 354-359.

Centella Asiatica Extract(0.5Ppm)

Function:

1. Definition Centella Asiatica (Gotu Kola) Extract:

Centella Asiatica (Gotu Kola) Extract is a botanical ingredient derived from the leaves of the Centella Asiatica plant. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is commonly used in skincare products for its ability to improve skin elasticity, reduce inflammation, and promote collagen production. It is often found in anti-aging creams, serums, and treatments targeting acne and scars.

3. Usage Centella Asiatica (Gotu Kola) Extract:

When using skincare products containing Centella Asiatica Extract, it is important to patch test first to ensure compatibility with your skin. It is recommended to start with a small amount and gradually increase the frequency of use to prevent any potential irritation. Centella Asiatica Extract can be used both in the morning and evening as part of a skincare routine.

4. References:

- Kim, D. H., & Jeon, Y. D. (2018). Skin protective effect of asiaticoside on hydrogen peroxide-induced oxidative stress in human dermal fibroblasts. International Journal of Molecular Medicine, 41(6), 3443-3452.

- Bylka, W., Znajdek-Awizenz, P., Studzinska-Sroka, E., & Brzezinska, M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii I Alergologii, 30(1), 46.

- Shukla, A., Rasik, A. M., & Dhawan, B. N. (1999). Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytotherapy Research, 13(1), 50-54.

Madecassoside(0.3Ppm)

Function: Skin Conditioning, Antioxidant

1. Definition Madecassoside:

Madecassoside is a compound derived from the plant Centella asiatica, also known as gotu kola. It is a type of triterpenoid saponin that has been shown to have anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassoside is commonly used in skincare products for its ability to soothe and repair the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, madecassoside has been found to stimulate collagen production, making it a popular ingredient in anti-aging formulations.

3. Usage Madecassoside:

When using skincare products containing madecassoside, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to perform a patch test before using madecassoside products to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating madecassoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee J, Jung E, Lee J, Huh S, Boo YC, Hyun CG, et al. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 118(3), 511-516.

- Bylka W, Znajdek-Awizeń P, Studzińska-Sroka E, Brzezińska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Maquart FX, Bellon G, Chaqour B, Wegrowski Y. (1999). Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds. European Journal of Dermatology, 9(4), 289-296.

Asiaticoside(0.2Ppm)

Function: Perfuming, Skin Conditioning, Antioxidant

1. Definition Asiaticoside:

Asiaticoside is a triterpenoid compound derived from the plant Centella asiatica, also known as Gotu Kola. It is a natural ingredient known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Asiaticoside is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of scars and stretch marks. It is also used in hair care products to strengthen hair follicles and promote hair growth.

3. Usage Asiaticoside:

When using products containing Asiaticoside, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any allergic reactions. It is also advisable to consult with a dermatologist before incorporating Asiaticoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kimura Y, Sumiyoshi M. Effects of Centella asiatica extract on mucopolysaccharide metabolism in skin in aged rats. Planta Med. 2009;75(6):689-695.

- Bylka W, Znajdek-Awizenz P, Studzinska-Sroka E, Brzezinska M. Centella asiatica in cosmetology. Adv Dermatol Allergol. 2013;30(1):46-49.

- Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

Madecassic Acid(0.02Ppm)

Function: Skin Conditioning

1. Definition Madecassic Acid:

Madecassic Acid is a triterpenoid compound derived from the medicinal plant Centella asiatica, also known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassic Acid is commonly used in skincare products for its ability to improve skin texture, reduce redness and inflammation, and promote collagen production. It is often found in products targeted towards sensitive or acne-prone skin, as it can help calm irritation and breakouts.

3. Usage Madecassic Acid:

When using products containing Madecassic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. Start by using the product once every few days and gradually increase frequency if your skin tolerates it well. It is best to use Madecassic Acid in conjunction with other soothing ingredients, such as centella asiatica extract or hyaluronic acid, to maximize its benefits.

4. References:

- Lee JH, Kim HL, Lee MH, You YJ, Choi YJ, Park CW, Kim HC, Lee JY, Ahn KJ, An IS, An S. Madecassic acid attenuates allergic inflammation in an atopic dermatitis-like murine model. Int Immunopharmacol. 2016 Nov;40:362-369. doi: 10.1016/j.intimp.2016.09.023. Epub 2016 Sep 26. PMID: 27685721.

- Kim D, Kim SH, Chang YJ, Kim J, Kim Y. Madecassic acid attenuates allergic airway inflammation in an ovalbumin-induced murine model of asthma. Int Immunopharmacol. 2019 Jan;66:294-301. doi: 10.1016/j.intimp.2018.11.003. Epub 2018 Nov 6. PMID: 30414514.

- Park MY, Kwon HJ, Sung MK. Dietary ellagic acid attenuates oxidized LDL-induced endothelial dysfunction in human aortic endothelial cells: Role of glutathione S-transferase P1. Food Chem Toxicol. 2013 May;55:100-6. doi: 10.1016/j.fct.2013.01.040. Epub 2013 Feb 1. PMID: 23376370.

Asiatic Acid(0.02Ppm)

Function: Skin Conditioning, Stabilising

1. Definition Asiatic Acid:

Asiatic acid is a triterpenoid compound found in plants such as Centella asiatica, commonly known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound healing properties, making it a popular ingredient in skincare products.

2. Use:

Asiatic acid is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce inflammation, promote collagen production, and improve skin elasticity. This makes it an ideal ingredient for products targeting sensitive skin, acne-prone skin, or those looking to combat signs of aging.

3. Usage Asiatic Acid:

When using skincare products containing Asiatic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Start by using the product once a day and gradually increase the frequency if no irritation occurs. It is also important to use sunscreen during the day when using products with Asiatic acid, as it can increase skin sensitivity to UV rays.

4. References:

- Lee JH, et al. (2018). Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke.

- Bylka W, et al. (2013). Centella asiatica in cosmetology.

- Kimura Y, et al. (2008). Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest in human liver cancer cells.