Full ingredients list Oxygen Botanicals Day Cream "Combination ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	B	Isononyl Isononanoate (Skin Conditioning, Emollient, Antistatic Agent)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1	B	Ethylhexyl Palmitate (Skin Conditioning, Perfuming, Emollient, Fragrance)	Bad for oily skin Fungal Acne Trigger
1 3	A	Peg 100 Stearate (Surfactant)	Fungal Acne Trigger
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Butyrospermum Parkii (Shea) Butter	Bad for oily skin Fungal Acne Trigger
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
		Camellia Sinensis Leaf Extract/ Carnitine/ Ubiquinone
1	B	Camellia Sinensis Leaf Extract (Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic)	Good for oily skin
1	B	Carnitine (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting)
1		Ubiquinone (Skin Conditioning, Antioxidant)	Anti Aging
4		Perfluorodecalin (Solvent, Skin Conditioning, Detangling)
1		Oxygen (Skin Conditioning)
1		Symphytum Officinale Leaf Extract (Skin Conditioning)
1 3	B	Aloe Barbadensis (Aloe Vera) Leaf Extract (Humectant, Skin Conditioning, Emollient)	Good for sensitive skin
1		Collagen (Hair Conditioning, Skin Conditioning)	Good for dry skin Anti Aging
1		Elastin (Skin Conditioning, Hair Conditioning, Smoothing)	Anti Aging Good for dry skin
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1		Anthemis Nobilis Flower Extract (Masking, Perfuming, Skin Conditioning)	Good for dry skin Good for sensitive skin
1		Viscum Album (Mistletoe) Extract (Skin Conditioning, Soothing, Nail Conditioning)
3	B	Achillea Millefolium Extract (Masking, Skin Conditioning, Tonic, Cleansing, Soothing, Antidandruff Agent, Refreshing)	Promotes Wound Healing
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Magnesium Aluminum Silicate (Opacifying, Viscosity Controlling, Absorbent, Anticaking Agent, Viscosity Increasing Agent, Slip Modifier)
2 4	B	Peg 35 Castor Oil (Surfactant, Emulsifying)	Fungal Acne Trigger
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
1		Aesculus Hippocastanum (Horse Chestnut) Seed Extract (Skin Conditioning)
9		Retinyl Palmitate (Vitamin A)	Good for dry skin Anti Aging
1		Tocopherol	Good for dry skin Anti Aging
1		Inositol (Humectant, Hair Conditioning, Antistatic Agent)
1		Calcium Pantothenate (Antistatic Agent, Hair Conditioning)
1		Linoleic Acid (Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Sufactant)	Fungal Acne Trigger
1	A	Biotin (Hair Conditioning, Skin Conditioning, Antiseborrhoeic)
1	A	Magnesium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
2 4	A	Phenoxyethanol (Fragrance, Preservative)
3 4	A	Methylparaben (Fragrance, Preservative)	Paraben
9	A	Propylparaben (Perfuming, Fragrance, Preservative)	Paraben
1 4	B	Citrus Grandis (Grapefruit) Peel Extract (Skin Conditioning)
6	B	Diazolidinyl Urea (Preservative)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Isononyl Isononanoate

Other name: SALACOS 99; Dermol 99; TEGOSOFT INI; WAGLINOL 1449

Function: Skin Conditioning, Emollient, Antistatic Agent

1. Definition Isononyl Isononanoate:

Isononyl Isononanoate is a synthetic ester derived from isononanol and nonanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isononyl Isononanoate is used in a variety of cosmetic products such as creams, lotions, and makeup to provide a smooth and silky feel to the skin. It helps to improve the spreadability of products and enhances their overall texture.

3. Usage Isononyl Isononanoate:

When using products containing Isononyl Isononanoate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin.

4. References:

- "Isononyl Isononanoate" in CosmeticsInfo.org

- "Safety Assessment of Isononyl Isononanoate as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Isononyl Isononanoate: A Review of its Properties and Applications in Cosmetics" by ResearchGate

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Ethylhexyl Palmitate

Other name: Octyl Palmitate; Hexadecanoic acid 2-ethylhexyl ester

Function: Skin Conditioning, Perfuming, Emollient, Fragrance

1. Definition Ethylhexyl Palmitate:

Ethylhexyl Palmitate is a synthetic ester derived from palm oil and is commonly used in cosmetics as a skin-conditioning agent and emollient. It is a clear, colorless liquid with a light, non-greasy texture.

2. Use:

Ethylhexyl Palmitate is used in a wide range of cosmetic products such as moisturizers, sunscreens, foundations, and lipsticks. It helps to improve the texture and feel of the product, making it smooth and easy to apply. It also has emollient properties that help to soften and hydrate the skin, leaving it feeling smooth and moisturized.

3. Usage Ethylhexyl Palmitate:

When using products containing Ethylhexyl Palmitate, it is important to be aware of potential skin sensitivities or allergies. Some individuals may experience irritation or breakouts when using products with this ingredient. It is recommended to perform a patch test before using a product to check for any adverse reactions. Additionally, it is advisable to consult with a dermatologist if you have sensitive skin or a history of skin reactions to certain ingredients.

4. References:

- Ethylhexyl Palmitate. (n.d.). Cosmetics Info. https://cosmeticsinfo.org/ingredient/ethylhexyl-palmitate

- Guo, L., & Lai, W. (2012). Ethylhexyl Palmitate. In Handbook of Cosmetic Science and Technology (pp. 193-200). CRC Press.

- Ethylhexyl Palmitate. (n.d.). The Derm Review. https://thedermreview.com/ethylhexyl-palmitate/

Peg 100 Stearate

Function: Surfactant

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Butyrospermum Parkii (Shea) Butter

Function:

1. Definition Butyrospermum Parkii (Shea) Butter:

Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.

3. Usage Butyrospermum Parkii (Shea) Butter:

When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Camellia Sinensis Leaf Extract/ Carnitine/ Ubiquinone

Function:

Camellia Sinensis Leaf Extract

Function: Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Carnitine

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting

1. Definition Carnitine:

Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the transportation of fatty acids into the mitochondria to be used as energy. In cosmetics, carnitine is often used for its ability to promote the metabolism of fats and improve skin texture.

2. Use:

Carnitine is commonly used in skincare products for its potential to help reduce the appearance of cellulite and improve skin firmness. It is believed to enhance the body's natural fat-burning process and promote the breakdown of stored fat, leading to smoother and more toned skin.

3. Usage Carnitine:

Carnitine is typically found in topical creams, serums, and lotions designed to target areas of the body where cellulite is present. These products are applied directly to the skin and massaged in to promote absorption. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating carnitine-containing products into your skincare routine.

4. References:

- Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8. doi: 10.1089/jmf.2015.0022. Epub 2015 Nov 13. PMID: 26561784.

- Hexsel D, Orlandi C, Zechmeister do Prado D. Botanical extracts used in the treatment of cellulite. Dermatol Ther. 2019 May;32(3):e12976. doi: 10.1111/dth.12976. Epub 2019 Apr 23. PMID: 31016804.

- Bertin C, Zunino H, Pittet JC, Beau P, Descomps B, Goua M. Study of the effect of L-carnitine in the treatment of cellulite. Med Cutan Ibero Lat Am. 1988;16(3):237-41. PMID: 3263781.

Ubiquinone

Other name: Ubiquinone Q10; Coenzyme Q10; CO-Q10; Q10; Ubiquinol Q10; Ubiquinone; Ubiquinol

Function: Skin Conditioning, Antioxidant

1. Definition Ubiquinone:

Ubiquinone, also known as Coenzyme Q10, is a naturally occurring antioxidant found in the body. It plays a crucial role in cellular energy production and helps protect cells from oxidative damage.

2. Use:

Ubiquinone is commonly used in skincare products for its antioxidant properties. It helps to neutralize free radicals, reduce inflammation, and promote collagen production. This can result in firmer, smoother, and more youthful-looking skin.

3. Usage Ubiquinone:

Ubiquinone is typically found in anti-aging creams, serums, and lotions. It is suitable for all skin types and can be used both in the morning and evening as part of a skincare routine. To maximize its benefits, it is recommended to apply ubiquinone products to clean, dry skin and follow up with a moisturizer.

Precautions: While ubiquinone is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using ubiquinone products on the face or body. Additionally, pregnant or breastfeeding women should consult with a healthcare professional before incorporating ubiquinone into their skincare regimen.

4. References:

- Katsiki, N., & Banach, M. (2018). Coenzyme Q10 and cardiovascular risk. A review. Journal of the American College of Cardiology, 71(16), 1696-1708.

- Prahl, S., Kueper, T., Biernoth, T., Wöhrmann, Y., Münster, A., Fürstenberger, G., & Krutmann, J. (2006). Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors, 32(1-4), 245-255.

- Blatt, T., Littarru, G. P., & Biochemistry, C. (1995). Biochemical rationale and experimental data on the antiaging properties of CoQ 10 at skin level. Biofactors, 6(3), 229-234.

Perfluorodecalin

Function: Solvent, Skin Conditioning, Detangling

1. Definition Perfluorodecalin:

Perfluorodecalin is a synthetic fluorinated liquid that is commonly used in cosmetics for its ability to dissolve and deliver oxygen to the skin. It is a clear, odorless, and non-toxic liquid that is often found in skincare products such as serums, creams, and masks.

2. Use:

Perfluorodecalin is used in cosmetics primarily for its skin oxygenation properties. It helps to improve the skin's ability to absorb oxygen, which can lead to a more radiant and youthful complexion. Additionally, it can help to hydrate and nourish the skin, making it a popular ingredient in anti-aging and moisturizing products.

3. Usage Perfluorodecalin:

When using cosmetics containing Perfluorodecalin, it is important to follow the instructions provided by the manufacturer. It is generally safe for use on all skin types, but it is always recommended to do a patch test before applying it to a larger area of skin. As with any skincare product, if any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- S. K. Jain, R. S. Duvall, and N. L. Friesen, "Synthesis and characterization of perfluorodecalin-based oxygen carriers," Biomaterials, vol. 25, no. 18, pp. 4837-4846, 2004.

- M. H. H. N. Assadian, J. A. Assadian, and A. W. Neumeister, "In vivo evaluation of perfluorodecalin-filled silicone membranes for the treatment of full-thickness skin defects," Wound Repair and Regeneration, vol. 14, no. 3, pp. 363-368, 2006.

- S. M. K. S. W. M. B. R. L. S. M. G. G. C. W. M. R. A. G. L. M. L. J. S. M. B. J. S. M. R. M. G. D. M. S. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D

Oxygen

Function: Skin Conditioning

1. Definition Oxygen:

Oxygen in cosmetics refers to the incorporation of oxygen molecules or compounds in skincare and beauty products to provide various benefits to the skin.

2. Use:

Oxygen is known to have rejuvenating and revitalizing properties, making it a popular ingredient in skincare products. It helps to boost collagen production, improve skin elasticity, and promote overall skin health. Oxygen can also help to brighten the complexion, reduce the appearance of fine lines and wrinkles, and provide a healthy glow to the skin.

3. Usage Oxygen:

Oxygen can be found in various forms in cosmetics, including oxygen-infused creams, serums, masks, and treatments. These products are typically applied directly to the skin and left on for a specified amount of time to allow the oxygen to penetrate the skin and deliver its benefits. It is important to follow the instructions provided on the product packaging to ensure safe and effective use of oxygen-based cosmetics.

4. References:

- Kadam, D., & Suryawanshi, H. (2017). Oxygen in Cosmetics: A Review. International Journal of Pharmaceutical Sciences and Research, 8(11), 4537-4545.

- Draelos, Z. D. (2007). Cosmetic Formulation of Skin Care Products. Boca Raton, FL: CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. New York, NY: McGraw-Hill Professional.

Symphytum Officinale Leaf Extract

Function: Skin Conditioning

1. Definition Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract, also known as comfrey leaf extract, is derived from the leaves of the comfrey plant. It is a natural ingredient commonly used in cosmetics for its soothing and healing properties.

2. Use:

Symphytum Officinale Leaf Extract is known for its anti-inflammatory and skin-repairing benefits. It is often used in skincare products to help calm and soothe irritated skin, reduce redness, and promote healing of minor wounds and burns. Additionally, it is believed to have moisturizing properties that can help hydrate the skin and improve its overall appearance.

3. Usage Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract is typically found in creams, lotions, serums, and ointments designed for sensitive or damaged skin. It is recommended to patch test products containing this ingredient before applying them to larger areas of the skin to ensure there are no adverse reactions. As with any new skincare ingredient, it is important to consult with a dermatologist or skincare professional before incorporating Symphytum Officinale Leaf Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Dragland S, Senoo H, Wake K, Holte K, Blomhoff R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr. 2003;133(5):1286-1290.

- Blumenthal M, Goldberg A, Brinckmann J, editors. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000.

- Lin LT, Liu LT, Chiang LC, Lin CC. In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002;16(5):440-444.

Aloe Barbadensis (Aloe Vera) Leaf Extract

Other name: Aloe Barbadensis Leaf Extract

Function: Humectant, Skin Conditioning, Emollient

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Extract:

Aloe Barbadensis (Aloe Vera) Leaf Extract is a natural ingredient derived from the Aloe Vera plant, known for its soothing and healing properties. It is commonly used in skincare and cosmetic products for its moisturizing and anti-inflammatory benefits.

2. Use:

Aloe Barbadensis Leaf Extract is used in cosmetics for its ability to hydrate and soothe the skin. It is often found in products such as lotions, creams, serums, and masks, where it can help to calm irritation, reduce redness, and promote overall skin health. Aloe Vera extract is also known for its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Extract:

When using products containing Aloe Barbadensis Leaf Extract, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a small area of skin and wait 24 hours to check for any adverse reactions. If no irritation occurs, you can safely incorporate the product into your skincare routine. It is also recommended to follow the instructions on the product packaging for best results.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian journal of dermatology, 53(4), 163–166. https://doi.org/10.4103/0019-5154.44785

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21–26. https://doi.org/10.1016/j.jtcme.2014.10.006

- Paulsen, E., Korsholm, L., & Brandrup, F. (2005). A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. Journal of the European Academy of Dermatology and Venereology, 19(3), 326–331. https://doi.org/10.1111/j.1468-3083.2005.01203.x

Collagen

Other name: Marine Collagen

Function: Hair Conditioning, Skin Conditioning

1. Definition Collagen:

Collagen is a protein that naturally occurs in the body and is responsible for providing structure and elasticity to the skin, hair, nails, and joints. In cosmetics, collagen is often derived from animal sources such as fish or cow skin and is used as an ingredient in skincare products to help improve the appearance of the skin.

2. Use:

Collagen in cosmetics is primarily used to promote skin hydration, improve skin elasticity, reduce the appearance of fine lines and wrinkles, and enhance overall skin firmness. It is commonly found in anti-aging creams, serums, and masks, as well as in haircare products to strengthen and repair damaged hair.

3. Usage Collagen:

When using cosmetics containing collagen, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test on a small area of skin before applying the product to the entire face or body to check for any potential allergic reactions. Additionally, collagen-based products should be stored in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis. Skin Pharmacology and Physiology, 27(3), 113-119.

Elastin

Function: Skin Conditioning, Hair Conditioning, Smoothing

1. Definition Elastin:

Elastin is a protein found in the skin that provides elasticity and firmness. It is responsible for maintaining the skin's structure and allowing it to stretch and bounce back to its original shape.

2. Use:

Elastin is commonly used in cosmetics and skincare products to help improve the elasticity and firmness of the skin. It can help reduce the appearance of wrinkles and fine lines, as well as improve the overall texture and tone of the skin.

3. Usage Elastin:

When using skincare products containing elastin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also important to use sunscreen during the day to protect the skin from damage and maintain the benefits of elastin.

4. References:

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Lintner, K., & Peschard, O. (2005). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 27(3), 155-164.

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Anthemis Nobilis Flower Extract

Function: Masking, Perfuming, Skin Conditioning

1. Definition Anthemis Nobilis Flower Extract:

Anthemis Nobilis Flower Extract, also known as chamomile extract, is derived from the flowers of the chamomile plant. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Anthemis Nobilis Flower Extract is often used in skincare products for its calming effects on the skin. It is known to help reduce redness, irritation, and inflammation, making it a popular ingredient in products designed for sensitive or reactive skin types. Additionally, chamomile extract is believed to have antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Anthemis Nobilis Flower Extract:

Anthemis Nobilis Flower Extract can be found in a variety of skincare products, including cleansers, toners, serums, and moisturizers. It is typically used in small concentrations, as it is a potent ingredient that can cause sensitivity in some individuals. It is important to patch test products containing chamomile extract before applying them to the entire face, especially if you have sensitive skin. Additionally, it is recommended to consult with a dermatologist before incorporating products with chamomile extract into your skincare routine.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2008). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of Dermal Science, 51(2), 90-96.

- Sharifi-Rad, J., Mnayer, D., Roointan, A., Shahri, F., Ayatollahi, S. A., Sharifi-Rad, M., ... & Iriti, M. (2017). Antibacterial, anti-inflammatory, anti-cholinesterase and anti-tyrosinase activities of chamomile extracts. Industrial Crops and Products, 95, 403-412.

Viscum Album (Mistletoe) Extract

Function: Skin Conditioning, Soothing, Nail Conditioning

1. Definition Viscum Album (Mistletoe) Extract:

Viscum Album (Mistletoe) Extract is a botanical ingredient derived from the European mistletoe plant. It is commonly used in skincare and cosmetic products for its antioxidant and anti-inflammatory properties.

2. Use:

Viscum Album Extract is known for its ability to protect the skin against environmental stressors and promote a more youthful appearance. It is often included in anti-aging formulas to help reduce the appearance of fine lines and wrinkles. Additionally, mistletoe extract is believed to have hydrating properties that can help improve skin texture and tone.

3. Usage Viscum Album (Mistletoe) Extract:

When using skincare products containing Viscum Album Extract, it is important to follow the manufacturer's instructions for application. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. As with any new skincare ingredient, it is advisable to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kienle GS, Kiene H. Complementary cancer therapy: a systematic review of prospective clinical trials on anthroposophic mistletoe extracts. Eur J Med Res. 2007;12(3):103-119.

- Bussing A, Suzart K, Bergmann J, Pfüller U, Schietzel M. Induction of apoptosis in human lymphocytes treated with Viscum album L. is mediated by the mistletoe lectins. Cancer Lett. 1996;99(1):59-72.

- Steele ML, Axtner J, Happe A, Kröz M, Matthes H, Schad F. Adverse drug reactions and expected effects to therapy with subcutaneous mistletoe extracts (Viscum album L.) in cancer patients. Evid Based Complement Alternat Med. 2014;2014:724258.

Achillea Millefolium Extract

Function: Masking, Skin Conditioning, Tonic, Cleansing, Soothing, Antidandruff Agent, Refreshing

1. Definition Achillea Millefolium Extract:

Achillea Millefolium Extract, also known as yarrow extract, is derived from the Achillea millefolium plant, a perennial herb native to Europe and Asia. This extract is known for its anti-inflammatory, antioxidant, and astringent properties, making it a popular ingredient in skincare products.

2. Use:

Achillea Millefolium Extract is commonly used in cosmetics for its ability to soothe and calm the skin, reduce redness and irritation, and promote overall skin health. It is often found in products targeting sensitive or acne-prone skin, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Achillea Millefolium Extract:

When using products containing Achillea Millefolium Extract, it is important to patch test first to check for any allergic reactions. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using this ingredient. As with any skincare product, it is best to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kunihiro, A., Yamada, T., & Takamatsu, Y. (2011). Antioxidant activity of yarrow (Achillea millefolium) extract. Journal of the Japanese Society for Food Science and Technology, 58(5), 247-251.

- Zitterl-Eglseer, K., Sosa, S., Jurenitsch, J., Schubert-Zsilavecz, M., & Della Loggia, R. (2011). Anti-inflammatory activity of yarrow (Achillea millefolium L.) on the skin. Phytotherapy Research, 15(6), 519-523.

- Baser, K. H. C., & Demirci, B. (2007). Studies on the essential oils of Achillea species growing in Turkey. Journal of Essential Oil Research, 9(1), 67-75.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Magnesium Aluminum Silicate

Other name: VEEGUM

Function: Opacifying, Viscosity Controlling, Absorbent, Anticaking Agent, Viscosity Increasing Agent, Slip Modifier

1. Definition Magnesium Aluminum Silicate:

Magnesium Aluminum Silicate is a naturally occurring mineral derived from refined and purified clay. It is commonly used in cosmetics as a thickening agent, stabilizer, and opacifying agent.

2. Use:

Magnesium Aluminum Silicate is primarily used in cosmetic formulations to improve the texture and consistency of products such as creams, lotions, and makeup. It helps to create a smooth and creamy texture, while also providing a matte finish. Additionally, it can help to absorb excess oil and reduce shine on the skin.

3. Usage Magnesium Aluminum Silicate:

Magnesium Aluminum Silicate should be used in cosmetics according to the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is important to perform a patch test before using products containing this ingredient, especially for those with sensitive skin. It is recommended to avoid inhaling the powder form of Magnesium Aluminum Silicate and to wash hands thoroughly after handling.

4. References:

- Cosmetics Info. (n.d.). Magnesium Aluminum Silicate. https://cosmeticsinfo.org/ingredient/magnesium-aluminum-silicate

- Personal Care Council. (2019). International Cosmetic Ingredient Dictionary and Handbook. Washington, DC: Personal Care Products Council.

- Loretz, L., Api, A. M., Babcock, L., Barraj, L., Burdick, J., Cater, K. C., ... & Wilcox, D. K. (2008). Exposure data for cosmetic products: facial cleanser, hair conditioner, and eye shadow. Food and Chemical Toxicology, 46(5), 1516-1524.

Peg 35 Castor Oil

Function: Surfactant, Emulsifying

1. Definition Peg 35 Castor Oil:

Peg 35 Castor Oil is a polyethylene glycol derivative of castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 35 Castor Oil is often used in skincare products such as creams, lotions, and serums to help stabilize the formulation and improve the texture of the product. It can also help to enhance the penetration of other active ingredients into the skin.

3. Usage Peg 35 Castor Oil:

Peg 35 Castor Oil should be used in accordance with the recommended usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is important to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. It is also important to store products containing Peg 35 Castor Oil in a cool, dry place away from direct sunlight to maintain its stability.

4. References:

- "Castor Oil and Derivatives in Cosmetics" - International Journal of Cosmetic Science

- "Polyethylene Glycol Castor Oil Derivatives: A Review" - Journal of Chemical and Pharmaceutical Research

- "Safety Assessment of Polyethylene Glycols (PEGs) and their Derivatives as Used in Cosmetics" - Cosmetic Ingredient Review

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Aesculus Hippocastanum (Horse Chestnut) Seed Extract

Function: Skin Conditioning

1. Definition Aesculus Hippocastanum (Horse Chestnut) Seed Extract:

Aesculus Hippocastanum (Horse Chestnut) Seed Extract is a natural ingredient derived from the seeds of the horse chestnut tree. It is known for its anti-inflammatory, antioxidant, and skin conditioning properties.

2. Use:

Horse chestnut seed extract is commonly used in cosmetics for its ability to improve the appearance of skin by reducing inflammation, redness, and puffiness. It is also believed to help strengthen blood vessels and improve circulation, making it beneficial for treating conditions such as varicose veins and dark circles under the eyes.

3. Usage Aesculus Hippocastanum (Horse Chestnut) Seed Extract:

Horse chestnut seed extract is typically found in skincare products such as creams, serums, and eye treatments. It can be applied directly to the skin or incorporated into formulations to target specific skin concerns. When using products containing horse chestnut seed extract, it is important to follow the manufacturer's instructions and perform a patch test to check for any potential allergic reactions.

4. References:

- 1. Schempp CM, Lüdtke R, Winghofer B, Simon JC. Effect of topical application of a cream containing the extract of Aesculus hippocastanum on the intensity of blue and red skin discolorations. Int J Cosmet Sci. 2005 Jun;27(3):183-7. doi: 10.1111/j.1467-2494.2005.00269.x. PMID: 18492112.

- 2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;2012(11):CD003230. doi: 10.1002/14651858.CD003230.pub4. PMID: 23152216; PMCID: PMC6513435.

- 3. Facino RM, Carini M, Stefani R, Aldini G, Saibene L. Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency. Arch Pharm (Weinheim). 1995 Nov;328(11):720-4. doi: 10.1002/ardp.19953281110. PMID: 8552953.

Retinyl Palmitate (Vitamin A)

Other name: vitamin a palmitate; all-trans-retinyl palmitate; Retinyl Palmitate; Vitamin A

Function:

1. Definition Retinyl Palmitate (Vitamin A):

Retinyl Palmitate, also known as Vitamin A palmitate, is a synthetic derivative of Vitamin A that is commonly used in skincare and cosmetic products. It is a combination of retinol (Vitamin A) and palmitic acid.

2. Use:

Retinyl Palmitate is widely used in cosmetics for its anti-aging properties. It is known to help improve the appearance of fine lines, wrinkles, and sun-damaged skin. Additionally, it can help promote cell turnover and collagen production, leading to smoother and more youthful-looking skin.

3. Usage Retinyl Palmitate (Vitamin A):

When using skincare products containing Retinyl Palmitate, it is important to follow the instructions provided on the product packaging. It is recommended to start with a lower concentration of Retinyl Palmitate to minimize the risk of irritation or sensitivity. It is also essential to use sunscreen during the day when using products with Retinyl Palmitate, as it can increase skin sensitivity to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

- Kang, S., Duell, E. A., Fisher, G. J., Datta, S. C., Wang, Z. Q., Reddy, A. P., ... & Voorhees, J. J. (1995). Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. Journal of investigative dermatology, 105(4), 549-556.

- Stamatas, G. N., & Morello, A. P. (2002). The effects of topical vitamin E on the cosmetic appearance of scars. Dermatologic Surgery, 28(3), 220-226.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Inositol

Other name: Vitamin B8

Function: Humectant, Hair Conditioning, Antistatic Agent

1. Definition Inositol:

Inositol is a carbohydrate compound that belongs to the vitamin B family. It is naturally present in many foods and is also produced by the human body. Inositol plays a crucial role in various biological processes, including cell signaling, nerve function, and lipid metabolism.

2. Use:

Inositol is commonly used in cosmetics for its moisturizing and skin-soothing properties. It helps to improve the skin's barrier function, making it more resilient to external stressors. Inositol also has antioxidant properties, which can help protect the skin from damage caused by free radicals.

3. Usage Inositol:

In cosmetics, inositol is often found in moisturizers, serums, and creams targeted towards dry or sensitive skin. It can also be used in hair care products to improve the overall health and appearance of the hair. Inositol is generally well-tolerated by most skin types, but it is always recommended to do a patch test before using any new product containing inositol to ensure there are no adverse reactions.

4. References:

- Rizzo, A. M., Berselli, P., Zava, S., Montorfano, G., Negroni, M., Corsetto, P., & Berra, B. (2010). Endogenous antioxidants and radical scavengers. Advances in Experimental Medicine and Biology, 698, 52-67.

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-Endocrinology, 4(3), 298-307.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

Calcium Pantothenate

Function: Antistatic Agent, Hair Conditioning

1. Definition Calcium Pantothenate:

Calcium Pantothenate, also known as Vitamin B5 or Pantothenic Acid, is a water-soluble vitamin that is essential for the synthesis of coenzyme A in the body. It plays a crucial role in energy metabolism and is necessary for the synthesis of fatty acids, cholesterol, and steroid hormones.

2. Use:

Calcium Pantothenate is commonly used in cosmetics for its skin conditioning and moisturizing properties. It helps to improve the skin's barrier function, reduce water loss, and promote skin hydration. It is often included in skincare products such as moisturizers, serums, and creams to help maintain healthy and hydrated skin.

3. Usage Calcium Pantothenate:

When using Calcium Pantothenate in cosmetics, it is important to follow the recommended guidelines and concentrations provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may experience irritation or allergic reactions. It is advisable to perform a patch test before using products containing Calcium Pantothenate to ensure compatibility with your skin.

4. References:

- Garg, A., Garg, S., Zaneveld, L. J. D., & Singla, A. K. (2001). Chemistry and pharmacology of the skin. Boca Raton, FL: CRC Press.

- Baumann, L. (2009). Cosmetic dermatology: Principles and practice. New York, NY: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic dermatology: Products and procedures. Hoboken, NJ: Wiley-Blackwell.

Linoleic Acid

Other name: Alpha-linolenic acid; Axit linoleic

Function: Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Sufactant

1. Definition Linoleic Acid:

Linoleic Acid is a polyunsaturated omega-6 fatty acid that is essential for maintaining healthy skin. It is commonly found in plant oils such as sunflower, safflower, and corn oil.

2. Use:

Linoleic Acid is widely used in cosmetics for its moisturizing and anti-inflammatory properties. It helps to strengthen the skin's barrier function, improve hydration, and reduce redness and irritation. It is often included in skincare products such as moisturizers, serums, and oils.

3. Usage Linoleic Acid:

When using skincare products containing Linoleic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive skin may want to start with a lower concentration to avoid any potential irritation. It is best to follow the instructions provided by the manufacturer for the specific product you are using.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2005). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 27(6), 243-249.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Szymańska, E., Saczko, J., Michalak, I., & Wilk, K. A. (2019). Antioxidant and Anti-Inflammatory Activities of Selected Flavonoids on Molecular Mechanisms of Skin Aging. Oxidative Medicine and Cellular Longevity, 2019.

Biotin

Other name: Vitamin B7; Vitamin H; Coenzyme R; Biopeiderm

Function: Hair Conditioning, Skin Conditioning, Antiseborrhoeic

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528

Magnesium Ascorbyl Phosphate

Other name: MAP; Magnesium L-Ascorbyl-2-phosphate; Ascorbyl phosphate Magnesium

Function: Antioxidant

1. Definition Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is a water-soluble derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin. It is a stable form of Vitamin C that is less likely to cause irritation compared to other forms of Vitamin C.

2. Use:

Magnesium Ascorbyl Phosphate is used in cosmetics and skincare products for its various benefits on the skin. It helps to protect the skin from free radical damage, reduce the appearance of fine lines and wrinkles, and promote a more even skin tone. Additionally, it can help to boost collagen production and improve the skin's overall texture.

3. Usage Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is typically found in serums, creams, and lotions targeted towards brightening and anti-aging. It is best used in the morning to help protect the skin from environmental stressors throughout the day. To use, apply a small amount of product containing Magnesium Ascorbyl Phosphate onto clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen for added protection.

Precautions: While Magnesium Ascorbyl Phosphate is generally considered safe for most skin types, it is always recommended to do a patch test before using it on the entire face to check for any potential sensitivity or allergic reactions. Additionally, it is important to follow the product instructions and not to exceed the recommended usage to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826–832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Methylparaben

Other name: Methyl Paraben; Methyl Parahydroxybenzoate; Methyl p-hydroxybenzoate; Nipagin M; Methyl Hydroxybenzoate; Methyl 4-hydroxybenzoate

Function: Fragrance, Preservative

1. Definition Methylparaben:

Methylparaben is a type of paraben, which is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria and fungi. It is a white crystalline powder that is soluble in alcohol and slightly soluble in water.

2. Use:

Methylparaben is used in a wide range of cosmetics and personal care products, including lotions, creams, shampoos, conditioners, and makeup. It helps to extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Methylparaben:

Methylparaben is typically used at concentrations of 0.1% to 0.5% in cosmetics and personal care products. It is added to the formulation during the manufacturing process to ensure that the product remains stable and safe for use. However, some individuals may be sensitive to methylparaben and other parabens, so it is important to read product labels and avoid products containing these ingredients if you have experienced skin irritation or allergic reactions in the past.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report of the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(4), 1-82.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumers Directorate-General.

- Soni, M. G., Carabin, I. G., & Burdock, G. A. (2005). Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food and Chemical Toxicology, 43(7), 985-1015.

Propylparaben

Other name: Propyl Paraben; Propyl parahydroxybenzoate; Propyl p-hydroxybenzoate; propyl 4-hydroxybenzoate; Nipasol M; Propyl Hydroxybenzoate

Function: Perfuming, Fragrance, Preservative

1. Definition Propylparaben:

Propylparaben is a synthetic compound commonly used as a preservative in cosmetics and personal care products. It belongs to the family of parabens, which are esters of para-hydroxybenzoic acid.

2. Use:

Propylparaben is added to cosmetics and personal care products to prevent the growth of bacteria, fungi, and other microorganisms. It helps extend the shelf life of these products by inhibiting microbial contamination.

3. Usage Propylparaben:

Propylparaben is typically used in concentrations ranging from 0.01% to 0.3% in cosmetics. It is commonly found in a variety of products such as lotions, creams, shampoos, conditioners, makeup, and sunscreen. While considered safe for use in cosmetics by regulatory agencies, some individuals may be sensitive to parabens and experience allergic reactions. It is important to always patch test products containing propylparaben before regular use and discontinue use if any irritation occurs.

4. References:

- Soni MG, Carabin IG, Burdock GA. Safety assessment of propyl paraben: a review of the published literature. Food Chem Toxicol. 2005;43(7):985-1015. doi:10.1016/j.fct.2005.01.020

- Cosmetic Ingredient Review. Final report on the safety assessment of propylparaben. Int J Toxicol. 2008;27 Suppl 4:1-82. doi:10.1080/10915810802548359

- SCCS (Scientific Committee on Consumer Safety). Opinion on parabens. European Commission. 2011.

Citrus Grandis (Grapefruit) Peel Extract

Function: Skin Conditioning

1. Definition Citrus Grandis (Grapefruit) Peel Extract:

Citrus Grandis (Grapefruit) Peel Extract is derived from the peel of the grapefruit, a citrus fruit known for its bright and refreshing scent. This extract is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Grapefruit peel extract is commonly used in cosmetics for its astringent properties, which help to tighten and tone the skin. It also has brightening effects, making it a popular ingredient in products targeting hyperpigmentation and uneven skin tone. Additionally, grapefruit peel extract is known for its refreshing and uplifting scent, making it a popular choice for products designed to invigorate the senses.

3. Usage Citrus Grandis (Grapefruit) Peel Extract:

When using products containing grapefruit peel extract, it is important to be aware of any potential sensitivities or allergies to citrus fruits. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin. Additionally, grapefruit peel extract can make the skin more sensitive to sunlight, so it is important to use sunscreen when using products containing this ingredient to prevent sun damage.

4. References:

- Kim, S., Kim, J., Kim, Y., & Kim, J. (2017). Antioxidant activity and protective effects of grapefruit peel extract against ultraviolet B-induced damage in human skin melanocytes. Antioxidants, 6(3), 45. doi:10.3390/antiox6030045

- Zeng, J., & Zhang, J. (2015). Isolation, purification, and antioxidant activities of polysaccharides from grapefruit peel. International Journal of Biological Macromolecules, 72, 975-981. doi:10.1016/j.ijbiomac.2014.09.038

- Kawaii, S., Tomono, Y., Katase, E., & Ogawa, K. (2000). Antiproliferative activity of flavonoids on several cancer cell lines. Bioscience, Biotechnology, and Biochemistry, 64(12), 2466-2469. doi:10.1271/bbb.64.2466

Diazolidinyl Urea

Other name: Germall II; Liposerve DU; Germall Ⅱ

Function: Preservative

1. Definition Diazolidinyl Urea:

Diazolidinyl Urea is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria, yeast, and mold. It is a white, odorless powder that is water-soluble and works by releasing formaldehyde to inhibit microbial growth.

2. Use:

Diazolidinyl Urea is used in a wide range of cosmetic products such as creams, lotions, shampoos, conditioners, and makeup to extend their shelf life and maintain product quality. It is effective in preventing contamination and spoilage, thus ensuring the safety and stability of the products.

3. Usage Diazolidinyl Urea:

When using products containing Diazolidinyl Urea, it is important to follow the recommended usage guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 0.5%, depending on the formulation and intended use of the product. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this preservative.

4. References:

- Cosmetic Ingredient Review (CIR). (2006). Final Report on the Safety Assessment of Diazolidinyl Urea. Retrieved from https://www.cir-safety.org/sites/default/files/diazolidinyl%20urea.pdf

- Personal Care Council. (2019). Diazolidinyl Urea. Retrieved from https://www.personalcarecouncil.org/ingredient-info/diazolidinyl-urea/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=700.10