Abra Therapeutics Intensive Azulene Eye Gel

1. Definition Lonicera Caprifolium (Honeysuckle) Flower Extract:

Lonicera Caprifolium (Honeysuckle) Flower Extract is derived from the flowers of the honeysuckle plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Lonicera Caprifolium Flower Extract is commonly used in cosmetics for its skin-conditioning and antioxidant benefits. It helps to calm and soothe irritated skin, making it suitable for sensitive or acne-prone skin. Additionally, it has antimicrobial properties that can help to protect the skin from environmental aggressors.

3. Usage Lonicera Caprifolium (Honeysuckle) Flower Extract:

Lonicera Caprifolium Flower Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 0.1% to 5%. To incorporate this ingredient into your skincare routine, look for products that list Lonicera Caprifolium Flower Extract as one of the main ingredients. Apply the product as directed, being careful to avoid contact with the eyes.

4. References:

- Kim, S. J., et al. (2016). Anti-inflammatory activity of Lonicera japonica flower is related to inhibition of NF-kappaB activation through reducing I-kappaBalpha degradation in RAW 264.7 cells. Journal of Ethnopharmacology, 177, 1-8.

- Park, E. J., et al. (2011). Anti-inflammatory activity of herbal medicines: inhibition of nitric oxide production and tumor necrosis factor-alpha secretion in an activated macrophage-like cell line. The American Journal of Chinese Medicine, 39(5), 943-958.

- Shin, T. Y., et al. (2000). Anti-allergic effects of Lonicera japonica Thunb. In vivo and in vitro. Inflammation Research, 49(5), 254-260.

1. Definition Chamomilla Recutita (Matricaria) Flower:

Chamomilla Recutita (Matricaria) Flower, commonly known as chamomile, is a daisy-like plant that belongs to the Asteraceae family. It is native to Europe, Western Asia, and North Africa and has been used for centuries in traditional medicine and skincare for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower is commonly used in cosmetics for its calming and healing properties. It is known to help reduce redness, inflammation, and irritation, making it a popular ingredient in products designed for sensitive or irritated skin. Chamomile extract is often included in skincare products such as creams, lotions, serums, and masks to help soothe and hydrate the skin.

3. Usage Chamomilla Recutita (Matricaria) Flower:

Chamomilla Recutita (Matricaria) Flower extract can be found in a variety of skincare products, including cleansers, toners, moisturizers, and masks. It is typically used in concentrations ranging from 0.5% to 5% in formulations. When using products containing chamomile extract, it is important to patch test first to check for any potential allergic reactions. It is also recommended to avoid using chamomile products on open wounds or broken skin.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895-901.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2008). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of Dermal Science, 50(2), 123-125.

- Kato, A., Minoshima, Y., Yamamoto, J., Adachi, I., Watson, A. A., Nash, R. J., ... & Tani, H. (2008). Protective effects of dietary chamomile tea on diabetic complications. Journal of Agricultural and Food Chemistry, 56(17), 8206-8211.

1. Definition Populus Tremuloides Bark Extract:

Populus Tremuloides Bark Extract is an extract derived from the bark of the quaking aspen tree, scientifically known as Populus tremuloides. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-soothing properties, making it a popular ingredient in skincare products.

2. Use:

Populus Tremuloides Bark Extract is commonly used in cosmetics for its various benefits for the skin. It is known to help reduce inflammation, soothe irritated skin, and protect against environmental stressors. Additionally, this extract has antioxidant properties that can help fight free radicals and promote a more youthful complexion.

3. Usage Populus Tremuloides Bark Extract:

Populus Tremuloides Bark Extract can be found in a wide range of skincare products, including serums, creams, and masks. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility and minimize the risk of irritation. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi, S. Y., et al. (2016). Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark. BMC Complementary and Alternative Medicine, 16, 198.

- Lee, S. H., et al. (2017). Anti-inflammatory and anti-oxidative effects of aspen bark extract in RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 46(8), 1015-1022.

- Kim, J. E., et al. (2018). Protective effects of aspen bark extract against UVB-induced skin damage in hairless mice. Journal of Photochemistry and Photobiology B: Biology, 185, 56-63.

1. Definition Ginkgo Biloba:

Ginkgo Biloba is a natural extract derived from the leaves of the Ginkgo tree, also known as the maidenhair tree. It is widely used in traditional Chinese medicine and has gained popularity in the cosmetic industry for its potential benefits for the skin.

2. Use:

Ginkgo Biloba is known for its antioxidant properties, which can help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory properties that can help soothe irritated skin and reduce redness. Additionally, Ginkgo Biloba is believed to improve circulation and promote collagen production, which can help improve the overall appearance and health of the skin.

3. Usage Ginkgo Biloba:

Ginkgo Biloba is commonly found in skincare products such as serums, creams, and masks. It can be applied topically to the skin, where it can help improve skin tone, texture, and overall complexion. It is important to follow the instructions provided on the product packaging and consult with a dermatologist before incorporating Ginkgo Biloba into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, S. Y., & Kim, M. S. (2015). Ginkgo biloba extract and bilberry anthocyanins improve skin function in women. Journal of Medicinal Food, 18(7), 787-790.

- Deters, A., Dauer, A., Schnetz, E., & Fartasch, M. (2001). High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin. Phytochemistry, 58(6), 949-958.

- Zhou, Y., Zheng, J., Li, Y., Xu, D. P., Li, S., Chen, Y. M., & Li, H. B. (2016). Natural polyphenols for prevention and treatment of cancer. Nutrients, 8(8), 515.

1. Definition Simmondsia Chinensis (Jojoba):

Simmondsia Chinensis, commonly known as Jojoba, is a shrub native to the southwestern United States and northern Mexico. The oil extracted from the seeds of this plant is a popular ingredient in cosmetics due to its moisturizing and nourishing properties.

2. Use:

Jojoba oil is commonly used in skincare products such as lotions, creams, and serums. It is known for its ability to mimic the skin's natural oils, making it suitable for all skin types, including sensitive and acne-prone skin. Jojoba oil is also used in hair care products to hydrate and condition the hair, leaving it soft and shiny.

3. Usage Simmondsia Chinensis (Jojoba):

Jojoba oil can be used on its own as a moisturizer or added to existing skincare and hair care products. It can be applied directly to the skin or hair, massaged in gently until fully absorbed. Jojoba oil can also be used as a carrier oil for essential oils or other active ingredients.

Precautions: While jojoba oil is generally considered safe for most people, it is always recommended to do a patch test before using it on a larger area of skin. Some individuals may be allergic to jojoba oil, so it is important to discontinue use if any irritation or allergic reaction occurs. It is also important to store jojoba oil in a cool, dark place to prevent it from going rancid.

4. References:

- Meier L, Stange R, Michalsen A, Uehleke B. Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study. Forsch Komplementmed. 2012;19(2):75-9. doi: 10.1159/000338076. Epub 2012 Apr 19. PMID: 22585103.

- Pazyar N, Yaghoobi R, Ghassemi MR, Kazerouni A, Rafeie E, Jamshydian N. Jojoba in dermatology: a succinct review. G Ital Dermatol Venereol. 2013 Dec;148(6):687-91. PMID: 24305429.

- Ranzato E, Martinotti S, Burlando B. Wound healing properties of jojoba liquid wax: an in vitro study. J Ethnopharmacol. 2011 Sep 1;134(2):443-9. doi: 10.1016/j.jep.2011.01.027. Epub 2011 Jan 27. PMID: 21276990.

1. Definition Algae/Seaweed/Kelp (Species Unspecified):

Algae, seaweed, and kelp are marine plants that are rich in vitamins, minerals, and antioxidants. They are commonly used in cosmetics for their nourishing and hydrating properties.

2. Use:

Algae, seaweed, and kelp are used in cosmetics for their ability to moisturize the skin, improve skin elasticity, and reduce inflammation. They are also known for their anti-aging properties and ability to protect the skin from environmental damage.

3. Usage Algae/Seaweed/Kelp (Species Unspecified):

Algae, seaweed, and kelp are typically found in skincare products such as moisturizers, serums, masks, and body scrubs. They can be used daily as part of a skincare routine to promote healthy, glowing skin. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Kim, S. K. (2011). Handbook of marine macroalgae: Biotechnology and applied phycology. John Wiley & Sons.

- Wang, H. M. D., Li, K. L., Yang, Y. K., Nai, Y. S., & Lee, T. H. (2018). An update on the therapeutic role of algae-derived enzymes in the treatment of skin aging. Marine Drugs, 16(8), 272.

- Gómez-Guillén, M. C., Giménez, B., López-Caballero, M. E., & Montero, M. P. (2011). Functional and bioactive properties of collagen and gelatin from alternative sources: A review. Food hydrocolloids, 25(8), 1813-1827.

1. Definition Camellia Sinensis (Green Tea):

Camellia Sinensis, commonly known as green tea, is a plant species native to East Asia, specifically China and Japan. It is widely cultivated for its leaves, which are used to produce various types of tea, including green tea, black tea, white tea, and oolong tea. Green tea is known for its high levels of antioxidants, particularly catechins, which have been linked to numerous health benefits.

2. Use:

Green tea extract is used in cosmetics for its antioxidant properties, which help protect the skin from damage caused by free radicals. It is also known for its anti-inflammatory and anti-aging properties, making it a popular ingredient in skincare products. Green tea can help reduce redness and irritation, improve skin tone and texture, and minimize the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis (Green Tea):

Green tea extract can be found in a variety of cosmetic products, including moisturizers, serums, masks, and eye creams. When using products containing green tea extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare product, it is recommended to perform a patch test before using it on a larger area of skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katiyar, S. K. (2011). Skin photoprotection by green tea: antioxidant and immunomodulatory effects. Current Drug Targets, 12(11), 1710-1719.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

- Boehm, K., Borrelli, F., Ernst, E., Habacher, G., Hung, S. K., Milazzo, S., ... & Horneber, M. (2009). Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews, (3).

1. Definition Chamomilla Recutita (Matricaria) Oil:

Chamomilla Recutita (Matricaria) Oil, also known as German chamomile oil, is an essential oil derived from the flowers of the Matricaria chamomilla plant. It is known for its calming and soothing properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Chamomilla Recutita (Matricaria) Oil is commonly used in cosmetics for its anti-inflammatory, anti-bacterial, and antioxidant properties. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness, soothe irritation, and promote healing. Additionally, chamomile oil is known for its calming aroma, making it a popular choice for products designed to promote relaxation and stress relief.

3. Usage Chamomilla Recutita (Matricaria) Oil:

Chamomilla Recutita (Matricaria) Oil can be found in a variety of cosmetic products, including creams, lotions, serums, and essential oil blends. It is typically used in small concentrations due to its potent nature, and should be diluted with a carrier oil before applying directly to the skin. It is important to perform a patch test before using chamomile oil on the skin, as some individuals may be allergic to it. Additionally, pregnant women should consult with a healthcare provider before using products containing chamomile oil.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- McKay, D. L., & Blumberg, J. B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

- Keefe, J. R., Mao, J. J., Soeller, I., & Li, Q. S. (2016). Chamomile and Marigold tea: Chemical characterization and evaluation of anticancer activity. Journal of Agricultural and Food Chemistry, 64(33), 6249-6256.

1. Definition Euphrasia Officinalis (Eyebright):

Euphrasia Officinalis, commonly known as Eyebright, is a small flowering plant that has been traditionally used in herbal medicine for its potential benefits for eye health and skin care. It is rich in antioxidants, tannins, and flavonoids, which are believed to have anti-inflammatory and soothing properties.

2. Use:

Eyebright is commonly used in cosmetics and skincare products for its potential to reduce puffiness, dark circles, and redness around the eyes. It is also believed to have a tightening and toning effect on the skin, making it a popular ingredient in anti-aging formulations. Additionally, Eyebright is known for its astringent properties, which can help to reduce excess oil production and tighten pores.

3. Usage Euphrasia Officinalis (Eyebright):

When using Eyebright in cosmetics, it is important to follow the recommended guidelines for safe use. It is typically found in the form of extracts, infusions, or essential oils, which can be added to creams, serums, and eye gels. Eyebright should be used in moderation to avoid any potential skin irritation or allergic reactions. It is always recommended to perform a patch test before using any new cosmetic product containing Eyebright.

4. References:

- Bone, K., & Mills, S. (2013). Principles and Practice of Phytotherapy: Modern Herbal Medicine. Churchill Livingstone.

- Hoffmann, D. (2003). Medical Herbalism: The Science and Practice of Herbal Medicine. Healing Arts Press.

- Chevallier, A. (2001). Encyclopedia of Herbal Medicine: The Definitive Home Reference Guide to 550 Key Herbs with all their Uses as Remedies for Common Ailments. DK.

1. Definition Azulene:

Azulene is a natural blue-colored compound derived from chamomile flowers. It is known for its anti-inflammatory and soothing properties, making it a popular ingredient in skincare products.

2. Use:

Azulene is commonly used in cosmetics for its calming effects on the skin. It is often found in products designed for sensitive or irritated skin, such as creams, serums, and masks. Azulene can help reduce redness, inflammation, and irritation, making it a beneficial ingredient for those with sensitive skin conditions like rosacea or eczema.

3. Usage Azulene:

When using skincare products containing azulene, it is important to follow the instructions provided by the manufacturer. Azulene is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to a larger area of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist. It is also important to store products containing azulene in a cool, dry place, away from direct sunlight, to maintain its potency.

4. References:

- Yoon, W. J., Moon, J. Y., Song, G., Lee, Y. K., Han, M. S., & Lee, J. S. (2010). Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-κB inactivation. Journal of agricultural and food chemistry, 58(18), 9927-9933.

- Kim, H. K., Park, H. R., Lee, J. S., Chung, T. S., Chung, H. Y., Chung, J., ... & Moon, H. R. (2003). Anti-inflammatory effects of a triple drug combination (vitamin E, vitamin C and α-lipoic acid) on adjuvant-induced arthritis in rats. The Korean Journal of Physiology & Pharmacology, 7(2), 119-124.

- Lee, J. S., Park, H. R., & Moon, H. R. (2002). Anti-inflammatory effects of α-lipoic acid in adjuvant-induced arthritis. Korean Journal of Physiology and Pharmacology, 6(4), 253-259.