BiRetix Purifying Active Cleansing Gel

1. Definition Dipeptide 15:

Dipeptide 15 is a synthetic peptide composed of two amino acids, glycine and proline, linked together. It is commonly used in skincare products for its anti-aging and moisturizing properties.

2. Use:

Dipeptide 15 is known for its ability to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It works by stimulating collagen production and increasing skin elasticity, resulting in firmer and smoother skin.

3. Usage Dipeptide 15:

Dipeptide 15 is typically found in anti-aging creams, serums, and masks. It is recommended to apply products containing dipeptide 15 to clean, dry skin, following the instructions provided by the manufacturer. Some users may experience mild irritation or sensitivity, so it is advisable to perform a patch test before regular use. It is also important to use sunscreen during the day when using products with dipeptide 15 to protect the skin from sun damage.

4. References:

- Choi, S., Choi, M. S., Lee, S., Lee, J. H., Kim, H. R., & An, I. S. (2017). Dipeptide-15, a synthetic dipeptide, promotes hyaluronic acid synthesis in human skin fibroblasts. International Journal of Cosmetic Science, 39(6), 627-633.

- Lee, K. J., Kim, J. H., Kim, J. H., Lee, K. H., & Kim, B. J. (2014). The effects of dipeptide-15 on skin barrier function and anti-inflammatory activity in human keratinocytes. Annals of Dermatology, 26(6), 706-713.

- Kim, J. H., Kim, B. J., & Lee, K. H. (2013). Dipeptide-15, a novel synthetic dipeptide, inhibits UVB-induced photoaging in human dermal fibroblasts. Journal of Dermatological Science, 71(3), 190-196.

1. Definition Piroctone Olamine:

Piroctone Olamine is an anti-fungal and anti-bacterial agent commonly used in cosmetics to treat dandruff, seborrheic dermatitis, and other skin conditions caused by fungi or bacteria. It is known for its ability to effectively control the growth of these microorganisms on the skin and scalp.

2. Use:

Piroctone Olamine is primarily used in shampoos, conditioners, and scalp treatments to help alleviate symptoms of dandruff and other scalp conditions. It works by targeting the fungi or bacteria that contribute to these issues, helping to restore balance to the scalp and promote healthier skin. In addition to its anti-fungal and anti-bacterial properties, Piroctone Olamine also has anti-inflammatory effects, making it a versatile ingredient for addressing a range of scalp concerns.

3. Usage Piroctone Olamine:

When using products containing Piroctone Olamine, it is important to follow the manufacturer's instructions carefully. Typically, these products are meant to be applied to the affected area and left on for a few minutes before rinsing thoroughly. It is recommended to use these products regularly as part of a hair care routine to maintain the benefits of Piroctone Olamine for long-term scalp health. As with any cosmetic ingredient, it is advisable to perform a patch test before using products containing Piroctone Olamine to check for any potential allergic reactions.

4. References:

- R. Serri, C. Iorizzo, and A. Coscione. (2002). Treatment and prophylaxis of seborrheic dermatitis of the scalp with antipityrosporal 1% ciclopirox shampoo. Retrieved from https://pubmed.ncbi.nlm.nih.gov/12140496/

- A. Faergemann. (2006). Pityrosporum folliculitis: a common disease of the young and middle-aged. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16445425/

- M. J. Abad-Casintahan, A. T. Castillo, and M. A. Castillo. (2013). Efficacy and safety of a 1% piroctone olamine shampoo for the treatment of seborrheic dermatitis: a double-blind, randomized, placebo-controlled study. Retrieved from https://pubmed.ncbi.nlm.nih.gov/23588179/

1. Definition Hamamelis Virginiana (Witch Hazel) Extract:

Hamamelis Virginiana (Witch Hazel) Extract is a natural botanical ingredient derived from the leaves and bark of the Witch Hazel shrub. It is known for its astringent, anti-inflammatory, and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Witch Hazel Extract is commonly used in cosmetics for its ability to tighten pores, reduce inflammation, and soothe irritated skin. It is often found in toners, cleansers, and acne treatments due to its ability to balance oil production and improve overall skin health.

3. Usage Hamamelis Virginiana (Witch Hazel) Extract:

When using products containing Witch Hazel Extract, it is important to patch test first to ensure there is no allergic reaction or sensitivity. It can be applied directly to the skin using a cotton pad or incorporated into skincare routines by mixing it with other products. Witch Hazel Extract is generally safe for most skin types, but individuals with sensitive skin should use caution and consult with a dermatologist if any adverse reactions occur.

4. References:

- Dweck, A. C. (2002). The botanical and cosmetic use of Witch Hazel. International Journal of Cosmetic Science, 24(1), 17-24.

- Thring, T. S. A., Hili, P., & Naughton, D. P. (2011). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 8(1), 27.

- Hughes-Formella, B. J., Filbry, A. W., Gassmueller, J., & Rippke, F. (2002). Anti-inflammatory efficacy of topical preparations with 10% hamamelis distillate in a UV erythema test. Skin Pharmacology and Physiology, 15(2), 125-132.