CCSD Correct Brightening Pads

1. Definition Silybum Marianum Fruit Extract:

Silybum Marianum Fruit Extract, also known as Milk Thistle Extract, is derived from the fruit of the Silybum Marianum plant. It is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Silybum Marianum Fruit Extract is commonly used in cosmetics for its ability to protect the skin from environmental stressors and free radicals. It is also believed to have skin-soothing and hydrating properties, making it suitable for sensitive or dry skin types.

3. Usage Silybum Marianum Fruit Extract:

Silybum Marianum Fruit Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate this ingredient into your skincare routine, look for products that list Silybum Marianum Fruit Extract as one of the top ingredients on the label.

4. References:

- Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs. 2001;61(14):2035-63.

- Surai PF, Silymarin as a natural antioxidant: an overview of the current evidence and perspectives. Antioxidants (Basel). 2015;4(1):204-47.

- Abenavoli L, Capasso R, Milic N, Capasso F. Milk thistle in liver diseases: past, present, future. Phytother Res. 2010;24(10):1423-32.

1. Definition Phyllanthus Emblica Fruit Extract:

Phyllanthus Emblica Fruit Extract, also known as Indian Gooseberry or Amla extract, is derived from the fruit of the Phyllanthus Emblica tree. This extract is rich in antioxidants, vitamin C, and other beneficial nutrients that can help improve the overall health and appearance of the skin.

2. Use:

Phyllanthus Emblica Fruit Extract is commonly used in cosmetics for its antioxidant properties, which can help protect the skin from environmental damage and premature aging. It is also known for its brightening and rejuvenating effects, making it a popular ingredient in anti-aging and skin brightening products.

3. Usage Phyllanthus Emblica Fruit Extract:

Phyllanthus Emblica Fruit Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is important to follow the instructions provided by the manufacturer and perform a patch test before using products containing this extract to ensure compatibility with your skin.

4. References:

- Kaur, I. P., & Saini, A. (2011). Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer. European Journal of Cancer Prevention, 20(3), 225-239.

- Thakur, N. S., & Bhargava, S. (2018). Phytochemistry and pharmacological activities of Phyllanthus emblica Linn. (Euphorbiaceae): an overview. Journal of Drug Delivery and Therapeutics, 8(6), 373-379.

- Prakash, O., & Kumar, A. (2013). Therapeutic potential of Phyllanthus emblica (amla): the ayurvedic wonder. Journal of Basic and Clinical Physiology and Pharmacology, 24(1), 93-105.

1. Definition Phosphoric Acid:

Phosphoric acid, also known as orthophosphoric acid, is a mineral acid commonly used in various industries, including the cosmetics industry. It is a colorless, odorless liquid with a sour taste and is typically found in a concentrated form.

2. Use:

Phosphoric acid is used in cosmetics as a pH adjuster and as a chelating agent. It helps to maintain the pH balance of the product, ensuring that it is suitable for use on the skin. Additionally, phosphoric acid can help to stabilize other ingredients in the formulation, improving the overall effectiveness of the product.

3. Usage Phosphoric Acid:

When using cosmetics containing phosphoric acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. Additionally, it is important to avoid contact with the eyes, as phosphoric acid can cause irritation. If contact does occur, rinse the affected area with water immediately.

4. References:

- G. L. Patrick. An Introduction to Medicinal Chemistry. Oxford University Press, 2013.

- R. M. S. Pereira. Handbook of Cosmetic Science and Technology. CRC Press, 2014.

- M. A. R. Meireles. Cosmetics: Science and Technology. Wiley, 2017.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Arctostaphylos Uva Ursi (Bearberry) Leaf Extract:

Arctostaphylos Uva Ursi (Bearberry) Leaf Extract is a natural ingredient derived from the leaves of the bearberry plant. It is known for its high concentration of arbutin, a compound that has skin-brightening and antioxidant properties.

2. Use:

Bearberry leaf extract is commonly used in cosmetics for its skin-brightening and lightening effects. It is often included in products designed to reduce the appearance of hyperpigmentation, age spots, and uneven skin tone. Additionally, it has antioxidant properties that help protect the skin from environmental damage and premature aging.

3. Usage Arctostaphylos Uva Ursi (Bearberry) Leaf Extract:

Bearberry leaf extract can be found in various skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-7% depending on the desired effect. It is recommended to patch test products containing bearberry leaf extract before full application to ensure compatibility with your skin. When using products with bearberry leaf extract, it is important to follow the instructions provided by the manufacturer to avoid any potential adverse reactions.

4. References:

- Saeedi M, Eslamifar M, Khezri K, et al. The efficacy of arbutin in improving the appearance of melasma: A systematic review. J Cosmet Dermatol. 2019;18(6):1656-1662. doi:10.1111/jocd.13002

- Rendon MI, Gaviria JI. Review of skin-lightening agents. Dermatol Surg. 2005;31(7 Pt 2):886-889. doi:10.1097/00042728-200507000-00011

- Huh SY, Shin JW, Na JI, Huh CH, Youn SW, Park KC. A randomized, double-blind, placebo-controlled trial of the effect of topical Arbutin on skin pigmentations in Korean patients. J Dermatolog Treat. 2009;20(2):76-81. doi:10.1080/09546630802046041

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

1. Definition Kojic Acid:

Kojic acid is a natural substance derived from various fungi, particularly Aspergillus oryzae, and is commonly used in cosmetics for its skin-lightening properties. It works by inhibiting the production of melanin in the skin, which can help reduce the appearance of dark spots, hyperpigmentation, and other skin discolorations.

2. Use:

Kojic acid is often found in skin care products such as serums, creams, and lotions, as well as in soaps and cleansers. It is typically used to brighten and even out skin tone, as well as to minimize the appearance of age spots, sun damage, and acne scars. Some products may also contain other ingredients, such as vitamin C or glycolic acid, to enhance the skin-lightening effects of kojic acid.

3. Usage Kojic Acid:

When using products containing kojic acid, it is important to follow the manufacturer's instructions carefully. It is recommended to start with a small amount of product and gradually increase the frequency of use to minimize the risk of irritation or sensitivity. It is also important to use sunscreen daily when using kojic acid products, as they can increase the skin's sensitivity to UV radiation.

4. References:

- Sarkar, R., Arora, P., & Garg, K. V. (2013). Cosmeceuticals for hyperpigmentation: What is available? Journal of Cutaneous and Aesthetic Surgery, 6(1), 4–11.

- Lim, J. T. (1999). Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. Dermatologic Surgery, 25(4), 282–284.

- Garcia, A., Fulton, J. E., & Huggins, J. (1999). Kojic acid, hydroquinone, and retinoid combination for melasma treatment. Journal of Drugs in Dermatology, 3(1), 68–72.

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

1. Definition Calcium Pantetheine Sulfonate:

Calcium Pantetheine Sulfonate is a water-soluble derivative of pantothenic acid (Vitamin B5) that is commonly used in cosmetics for its skin conditioning and moisturizing properties.

2. Use:

Calcium Pantetheine Sulfonate is often included in skincare products such as moisturizers, serums, and creams due to its ability to improve skin hydration and elasticity. It is known to help strengthen the skin barrier, enhance skin smoothness, and promote a healthy complexion.

3. Usage Calcium Pantetheine Sulfonate:

When using skincare products containing Calcium Pantetheine Sulfonate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use sunscreen during the day when using products with Calcium Pantetheine Sulfonate to protect the skin from sun damage.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Most pseudoceramides do not have ceramide-like biological activity: serine-pseudoceramide is a biological equivalent of ceramide. Journal of lipid research, 50(12), 2406-2413.

- Kim, H. J., Kim, J. H., Chie, E. K., & Young, J. J. (2008). The effects of calcium pantothenate on skin hydration, elasticity, and wrinkle formation in UVB-irradiated hairless mice. Bioscience, biotechnology, and biochemistry, 72(4), 961-964.

- Lee, S. H., & Lee, S. J. (2004). The effect of calcium pantothenate on skin hydration, flexibility, and wrinkle formation in UVB-irradiated hairless mice. Korean Journal of Dermatology, 42(8), 1026-1031.