CCSD Rx Reverse Tretinoin 0.05%

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

1. Definition Diisopropyl Dimer Dilinoleate:

Diisopropyl Dimer Dilinoleate is a synthetic compound commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from dimer acids and linoleic acid, and it has a clear, colorless appearance.

2. Use:

Diisopropyl Dimer Dilinoleate is primarily used in skincare products such as lotions, creams, and serums due to its ability to moisturize and soften the skin. It helps to improve the overall texture of the skin and enhance the spreadability of the product.

3. Usage Diisopropyl Dimer Dilinoleate:

When using products containing Diisopropyl Dimer Dilinoleate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for topical application, but individuals with sensitive skin may want to perform a patch test before using it on larger areas of the skin. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Safety Assessment of Diisopropyl Dimer Dilinoleate as Used in Cosmetics" Cosmetic Ingredient Review, 2014.

- "Diisopropyl Dimer Dilinoleate" The Derm Review, www.thedermreview.com.

- "Formulating with Diisopropyl Dimer Dilinoleate" Personal Care Magazine, www.personalcaremagazine.com.

1. Definition Aluminum:

Aluminum is a naturally occurring element that is commonly used in cosmetics as an ingredient in antiperspirants, eyeliners, lipsticks, and other beauty products. It is known for its ability to absorb moisture and provide a smooth texture to products.

2. Use:

Aluminum is used in cosmetics primarily for its ability to control sweat and odor in antiperspirants. In eyeliners and lipsticks, it is used as a pigment to provide color and opacity. Additionally, aluminum compounds are sometimes used as thickening agents or emollients in skincare products.

3. Usage Aluminum:

While aluminum is generally considered safe for use in cosmetics, some people may be sensitive to it and experience irritation or allergic reactions. It is important to patch test products containing aluminum before using them on a larger area of the skin. Additionally, prolonged exposure to high concentrations of aluminum in cosmetics may potentially lead to health concerns, such as neurotoxicity or hormone disruption. It is recommended to limit the use of aluminum-containing products and to opt for alternatives when possible.

4. References:

- Darbre, P. D. (2004). Aluminium, antiperspirants and breast cancer. Journal of Inorganic Biochemistry, 98(9), 1579-1586.

- Schikowski, T., et al. (2015). Association of air pollution with cognitive functions and its modification by APOE gene variants in elderly women. Environmental Research, 142, 10-16.

- Williams, H., et al. (2019). Aluminum and phosphorus in cosmetic products: A quantitative analysis. Journal of Cosmetic Science, 70(2), 105-116.

1. Definition Magnesium Silicate:

Magnesium Silicate, also known as talc, is a naturally occurring mineral composed of magnesium, silicon, and oxygen. It is commonly used in cosmetic formulations as an absorbent, anti-caking agent, and bulking agent.

2. Use:

Magnesium Silicate is used in cosmetics to improve the texture and feel of products. It helps to absorb excess moisture, oils, and sweat on the skin, making it ideal for use in powders, foundations, and other makeup products. Additionally, it helps prevent clumping and caking in powdered products, ensuring a smooth and even application.

3. Usage Magnesium Silicate:

Magnesium Silicate is generally recognized as safe for use in cosmetics, but there are some precautions to keep in mind. It is important to avoid inhaling talc powder as it may cause respiratory issues. Additionally, some studies have suggested a potential link between talc use and certain types of cancer, so it is advisable to use talc-free alternatives if you have concerns about its safety.

4. References:

- Farrar, M. D., et al. (2015). Talc, Magnesium Silicate, Asbestos and Human Cancer. Inhalation Toxicology, 27(5): 258-264.

- Loretz, L., Api, A. M., Barraj, L., Burdick, J., Dressler, W., Gettings, S. D., et al. (2018). Exposure Data for Personal Care Products: Hairspray, Spray Perfume, Liquid Foundation, Shampoo, Body Wash, and Solid Antiperspirant. Food and Chemical Toxicology, 114: 200-213.

- Cosmetic Ingredient Review. (2013). Final Report on the Safety Assessment of Talc. International Journal of Toxicology, 32(1): 5S-34S.

1. Definition Benzyl Alcohol:

Benzyl Alcohol is a clear, colorless liquid with a mild, pleasant aroma. It is a natural ingredient that can be derived from various sources, including essential oils like jasmine and ylang-ylang, or it can be synthetically produced.

2. Use:

Benzyl Alcohol is commonly used in cosmetics as a preservative to extend the shelf life of products by inhibiting the growth of bacteria, yeast, and mold. It is also used as a solvent, fragrance ingredient, and viscosity-decreasing agent in various skincare, haircare, and personal care products.

3. Usage Benzyl Alcohol:

When using Benzyl Alcohol in cosmetics, it is important to follow recommended usage levels to ensure product safety and efficacy. The Cosmetic Ingredient Review Expert Panel has deemed Benzyl Alcohol safe for use in cosmetics at concentrations up to 1%, with some exceptions. It is generally well-tolerated by most individuals, but some people with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Benzyl Alcohol, especially if you have a history of skin sensitivities.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.

- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol

1. Definition Silica Gel:

Silica gel is a desiccant commonly used in cosmetics to absorb excess moisture and prevent spoilage or degradation of products. It is a porous, granular form of silicon dioxide that is highly absorbent and non-toxic.

2. Use:

Silica gel is used in cosmetics to maintain the stability and shelf-life of products by absorbing excess moisture that can lead to bacterial growth, mold, or deterioration of active ingredients. It is commonly found in powdered cosmetics, such as loose powders, blushes, and eyeshadows, to prevent clumping and extend the product's lifespan.

3. Usage Silica Gel:

When using cosmetics containing silica gel, it is important to follow the manufacturer's instructions and guidelines. Avoid inhaling the powder or getting it in contact with the eyes, as it can cause irritation. Store products containing silica gel in a cool, dry place away from direct sunlight to prevent moisture absorption and maintain their effectiveness.

4. References:

- "Silica Gel: A Versatile Tool for the Manipulation of Drug Release in Topical Formulations" by J. C. Carreño-Gómez et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752184/)

- "Silica Gel: An Efficient and Versatile Catalyst for Organic Synthesis" by P. K. Parhi et al. (https://pubs.acs.org/doi/10.1021/acs.joc.8b02274)

- "Silica Gel: A Review of Its Adsorption Mechanism and Application in Water Treatment" by S. A. Al-Ghouti et al. (https://www.sciencedirect.com/science/article/abs/pii/S0043135410006307)

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

1. Definition Bha:

BHA, or beta hydroxy acid, is a type of chemical exfoliant commonly used in skincare products. It is oil-soluble, making it ideal for penetrating deep into the pores to unclog them and exfoliate dead skin cells.

2. Use:

BHA is primarily used in cosmetics and skincare products to treat acne, blackheads, and other skin concerns related to clogged pores. It is also known for its anti-inflammatory and antibacterial properties, making it effective in reducing redness and inflammation associated with acne.

3. Usage Bha:

When using products containing BHA, it is important to start with a lower concentration to avoid potential irritation, especially for those with sensitive skin. BHA can increase sun sensitivity, so it is essential to use sunscreen daily when incorporating BHA into your skincare routine. It is recommended to use BHA products in the evening to allow for maximum effectiveness without the risk of increased sun sensitivity.

4. References:

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455-461.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327-348.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.