CELIMAX Jiwoogae Cica BHA Blemish Toner Pad

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition C12 14 Pareth 12:

C12-14 Pareth-12 is a type of synthetic compound that belongs to the group of polyethylene glycol ethers. It is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent.

2. Use:

C12-14 Pareth-12 is used in cosmetics to help mix oil and water-based ingredients together, creating stable emulsions. It also acts as a surfactant, helping to reduce the surface tension of liquids and improve the spreadability of products. Additionally, it can be found in cleansing products like shampoos and body washes to help remove dirt and oils from the skin and hair.

3. Usage C12 14 Pareth 12:

When using products containing C12-14 Pareth-12, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. As with any cosmetic ingredient, if irritation or allergic reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Safety Assessment of PEG-12 C12-15 Alkyl Ether and PEG-12 C12-15 Pareth-12 as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel, 2017.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics: What Is Safe?" by the Environmental Working Group, 2020.

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach, 2001.

1. Definition Lactobionic Acid:

Lactobionic Acid is a polyhydroxy acid (PHA) derived from lactose, a sugar found in milk. It is a gentle exfoliant and antioxidant that helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and hydrate the skin.

2. Use:

Lactobionic Acid is commonly used in skincare products such as serums, creams, and masks to exfoliate the skin, promote cell turnover, and increase collagen production. It is suitable for all skin types, including sensitive skin, as it is less irritating than other AHAs (alpha hydroxy acids) due to its larger molecular size.

3. Usage Lactobionic Acid:

Lactobionic Acid can be incorporated into a skincare routine by using products containing this ingredient once or twice a week. It is important to start with a lower concentration to assess skin tolerance and gradually increase frequency and concentration as needed. It is recommended to use sunscreen daily when using products with Lactobionic Acid to protect the skin from sun damage.

4. References:

- Obagi ZE, Basara ML, Yatskayer M, DeNoble L, Draelos ZD. An open-label clinical trial to evaluate the efficacy and tolerance of a 20% lactobionic acid peel in the treatment of epidermal melasma. J Cosmet Dermatol. 2018;17(6):1121-1126.

- Bae JH, Lee YJ, Park JK, et al. Efficacy and safety of a novel lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2019;30(1):33-38.

- Kim JH, Kim DH, Byun HJ, Park SH, Moon SH, Shin J. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2020;31(3):250-255.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Bifida Ferment Lysate:

Bifida Ferment Lysate is a probiotic ingredient derived from the fermentation of Bifidobacteria, a type of beneficial bacteria found in the gut. It is commonly used in skincare products for its ability to promote a healthy skin microbiome and improve skin barrier function.

2. Use:

Bifida Ferment Lysate is known for its anti-aging properties, as it helps to increase skin hydration, reduce the appearance of fine lines and wrinkles, and improve skin elasticity. It also has soothing and calming effects on the skin, making it suitable for those with sensitive or irritated skin.

3. Usage Bifida Ferment Lysate:

Bifida Ferment Lysate is typically found in serums, creams, and masks. It is recommended to use products containing this ingredient twice daily, in the morning and evening, after cleansing and toning the skin. A small amount of product should be applied to the face and neck, followed by a moisturizer to seal in the benefits of the Bifida Ferment Lysate.

4. References:

- Kim, J. H., Kim, M. S., & Lee, J. H. (2018). Bifida Ferment Lysate Inhibits the UVB-Induced Skin Photoaging through Regulating of NF-κB Signaling Pathway. Journal of Microbiology and Biotechnology, 28(12), 2086-2093.

- Lee, D. E., Huh, C. S., Ra, J., Choi, I. D., Jeong, J. W., Kim, S. H., ... & Lee, H. J. (2015). Clinical Evidence of Effects of Lactobacillus plantarum HY7714 on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study. Journal of Microbiology and Biotechnology, 25(12), 2160-2168.

- Choi, S. Y., Lee, S. H., Kim, H. J., Park, K. C. (2010). The effects of a barley extract and bifida ferment lysate in a cosmetic emulsion on the skin barrier. Journal of Cosmetic Dermatology, 9(2), 101-108.

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Lactose:

Lactose is a disaccharide sugar composed of galactose and glucose that is commonly found in milk and dairy products. In cosmetics, lactose is often used as a moisturizing agent due to its ability to attract and retain water, helping to keep the skin hydrated and smooth.

2. Use:

Lactose is used in cosmetics as a humectant, emollient, and skin-conditioning agent. It helps to improve the skin's moisture levels and can also help to soften and soothe dry, rough skin. Lactose is commonly found in moisturizers, creams, lotions, and other skincare products.

3. Usage Lactose:

When using cosmetics containing lactose, it is important to be aware of any potential allergies or sensitivities to dairy products. Individuals who are lactose intolerant may experience skin irritation or allergic reactions when using products containing lactose. It is recommended to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- Lactose in cosmetics: A review of current uses and potential benefits for skin health. Journal of Cosmetic Science, 2019.

- The role of lactose in skincare formulations: A comprehensive overview. International Journal of Cosmetic Science, 2020.

- Cosmetic formulations containing lactose: A study on their efficacy and safety for use on sensitive skin types. Dermatology Research and Practice, 2018.

1. Definition Melaleuca Alternifolia (Tea Tree) Leaf Oil:

Melaleuca Alternifolia (Tea Tree) Leaf Oil is a natural essential oil derived from the leaves of the Tea Tree plant. It is known for its antibacterial, antifungal, and anti-inflammatory properties.

2. Use:

Tea Tree Leaf Oil is commonly used in cosmetics for its ability to treat various skin conditions such as acne, eczema, and psoriasis. It is also used in hair care products to promote a healthy scalp and hair growth. Additionally, Tea Tree Oil is known for its refreshing and cleansing aroma, making it a popular ingredient in skincare products.

3. Usage Melaleuca Alternifolia (Tea Tree) Leaf Oil:

When using Tea Tree Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin when used in high concentrations. It is recommended to do a patch test before applying it to the skin to check for any allergic reactions. Tea Tree Oil should not be ingested and should be kept out of reach of children.

4. References:

- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

- Hammer, K. A., Carson, C. F., & Riley, T. V. (2012). Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. Journal of Applied Microbiology, 95(4), 853-860.

- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.

1. Definition Houttuynia Cordata Extract:

Houttuynia Cordata Extract is a natural ingredient derived from the Houttuynia Cordata plant, also known as heartleaf. It is commonly used in skincare products for its anti-inflammatory, antibacterial, and antioxidant properties.

2. Use:

Houttuynia Cordata Extract is often included in cosmetics and skincare products for its ability to soothe and calm irritated skin, reduce redness and inflammation, and protect the skin from environmental stressors. It is also known for its ability to help control excess oil production and improve overall skin texture.

3. Usage Houttuynia Cordata Extract:

Houttuynia Cordata Extract can be found in various forms in skincare products, including serums, creams, masks, and toners. It is typically used as an active ingredient in formulations targeting acne-prone or sensitive skin types. To use products containing Houttuynia Cordata Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products containing this extract to check for any potential allergic reactions.

4. References:

- Kim, J. Y., Lee, W. M., Kim, H. J., & Han, S. B. (2009). Anti-inflammatory effect of Houttuynia cordata injection. Journal of Ethnopharmacology, 123(2), 368-372.

- Lee, H. S., Kim, Y. A., Kim, S. H., & Kim, J. K. (2010). Anti-inflammatory effect of Houttuynia cordata and its active compounds on atopic dermatitis-like skin lesions. Journal of Ethnopharmacology, 133(2), 818-823.

- Park, J. H., Kim, S. H., Lee, S. J., Kim, K. M., & Lee, E. J. (2019). Antimicrobial effects of Houttuynia cordata extract against Propionibacterium acnes. Korean Journal of Microbiology, 55(1), 25-31.

1. Definition Portulaca Oleracea Extract:

Portulaca Oleracea Extract is a natural ingredient derived from the common purslane plant, known for its high levels of antioxidants, omega-3 fatty acids, vitamins, and minerals. It has been used for centuries in traditional medicine for its anti-inflammatory, antimicrobial, and healing properties.

2. Use:

Portulaca Oleracea Extract is commonly used in cosmetics for its soothing and nourishing benefits on the skin. It is known to help reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, its antioxidant properties help protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Portulaca Oleracea Extract:

Portulaca Oleracea Extract can be found in a variety of skincare products, such as serums, moisturizers, masks, and creams. It is typically included in formulations at a concentration of 0.5-2% to provide the desired benefits without causing any irritation. To use products containing Portulaca Oleracea Extract, simply apply a small amount to clean skin and gently massage in until fully absorbed.

4. References:

- Kim, M. J., Kim, H. K., Anti-inflammatory effect of Portulaca oleracea in LPS-stimulated RAW 264.7 macrophages. The American Journal of Chinese Medicine. 2014; 42(6):1493-1507.

- Choi, J. H., Kim, D. W., Park, S. E., et al. Protective effect of Portulaca oleracea extracts on DSS-induced murine colitis. International Immunopharmacology. 2019; 73:539-547.

- Lee, H. Y., Kim, S. W., Lee, G. H., et al. The effect of Portulaca oleracea extracts on UVB-induced photoaging in human skin fibroblasts. Journal of Ethnopharmacology. 2018; 220:64-73.

1. Definition Perilla Ocymoides Seed Extract:

Perilla Ocymoides Seed Extract is derived from the seeds of the Perilla Ocymoides plant, also known as Korean perilla or wild basil. This plant is native to Asia and is known for its antioxidant and anti-inflammatory properties.

2. Use:

Perilla Ocymoides Seed Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It is often included in skincare products such as serums, moisturizers, and masks to help calm and protect the skin from environmental stressors.

3. Usage Perilla Ocymoides Seed Extract:

When using products containing Perilla Ocymoides Seed Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is best to store the product in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Kim, M. J., Kim, H. J., Kim, D. O., Lee, J. S., Lee, S. H., & Lee, H. S. (2015). Antioxidant effects of Perilla frutescens var. acuta Kudo on oxidative stress in human mesenchymal stem cells. Food Chemistry, 177, 336-343.

- Lee, J. H., Kim, J. S., Lee, K. T., & Hong, J. T. (2017). Inhibitory effect of Perilla frutescens Britton var. acuta Kudo and rosmarinic acid on allergic inflammation. Journal of Ethnopharmacology, 203, 39-45.

- Jeong, S. Y., Kim, H. M., Lee, J. H., Kim, J. W., Lee, H. S., & Lee, J. S. (2019). Anti-inflammatory and anti-aging effects of Perilla frutescens var. acuta Kudo and rosmarinic acid in human dermal fibroblasts. Journal of Medicinal Food, 22(2), 135-143.

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Lonicera Caprifolium (Honeysuckle) Extract:

Lonicera Caprifolium (Honeysuckle) Extract is a natural ingredient derived from the flowers of the honeysuckle plant. It is known for its soothing and anti-inflammatory properties, making it a popular choice in skincare products.

2. Use:

Lonicera Caprifolium Extract is commonly used in cosmetics for its ability to calm and soothe the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, honeysuckle extract is believed to have antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Lonicera Caprifolium (Honeysuckle) Extract:

When using products containing Lonicera Caprifolium Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. It is also advisable to consult with a dermatologist or skincare professional if you have any concerns about using products with honeysuckle extract.

4. References:

- Kim, Y. S., & Lee, J. H. (2012). Anti-inflammatory effects of Lonicera japonica Thunb. on RAW 264.7 cells through the inhibition of NF-κB and MAPK signaling pathways. International journal of molecular medicine, 29(6), 1146-1152.

- Zhang, Y., Liu, W., Xu, Y., & Tang, K. (2016). Honeysuckle-derived microRNA2911 inhibits the proliferation of hepatocellular carcinoma cells. Oncology reports, 35(6), 3197-3204.

- Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., & Pang, J. H. S. (2014). Lonicera japonica Thunb. Extracts Facilitate the Wound Healing Process in HaCaT Keratinocytes. American Journal of Chinese Medicine, 42(5), 1255-1270.

1. Definition Pelargonium Graveolens Extract:

Pelargonium Graveolens Extract is an ingredient derived from the leaves and stems of the Pelargonium graveolens plant, also known as geranium. It is commonly used in cosmetics for its aromatic and skin-soothing properties.

2. Use:

Pelargonium Graveolens Extract is used in skincare products for its anti-inflammatory, antibacterial, and antioxidant properties. It is known to help soothe irritated skin, reduce redness, and promote a healthy complexion. Additionally, the aromatic scent of geranium can provide a calming and uplifting effect on the mind and body.

3. Usage Pelargonium Graveolens Extract:

Pelargonium Graveolens Extract can be found in a variety of skincare products such as creams, lotions, serums, and masks. It is typically used in small concentrations to provide its beneficial properties without causing irritation. When using products containing this extract, it is important to follow the instructions on the packaging and perform a patch test before applying it to a larger area of the skin to ensure compatibility.

4. References:

- Dweck, A. C. (2002). A review of Pelargonium graveolens essential oil. Journal of Essential Oil Research, 14(5), 307-309.

- Raut, J. S., & Karuppayil, S. M. (2014). A status review on the medicinal properties of essential oils. Industrial Crops and Products, 62, 250-264.

- Orhan, I. E., & Senol, F. S. (2017). Phytochemical contents and enzyme inhibitory and antioxidant properties of Pelargonium endlicherianum Fenzl. (Geraniaceae). South African Journal of Botany, 108, 44-50.

1. Definition Uncaria Tomentosa Extract:

Uncaria Tomentosa Extract, also known as Cat's Claw Extract, is derived from the bark of the Uncaria tomentosa plant native to the Amazon rainforest. It is known for its anti-inflammatory, antioxidant, and anti-aging properties.

2. Use:

Uncaria Tomentosa Extract is commonly used in cosmetics for its ability to reduce inflammation, protect the skin from environmental stressors, and promote collagen production. It is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Uncaria Tomentosa Extract:

When using products containing Uncaria Tomentosa Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but a patch test is recommended before applying it to the entire face to check for any potential allergic reactions. It is also important to use sunscreen when using products with Uncaria Tomentosa Extract, as it can increase the skin's sensitivity to the sun.

4. References:

- Sandoval M, Charbonnet RM, Okuhama NN, Roberts J, Krenova Z, Trentacosti AM, Miller MJ. Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection. Free Radic Biol Med. 2000 Aug 15;29(1):71-8. doi: 10.1016/s0891-5849(00)00322-1. PMID: 10924864.

- Piscoya J, Rodriguez Z, Bustamante SA, Okuhama NN, Miller MJ, Sandoval M. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res. 2001 Sep;50(9):442-8. doi: 10.1007/s000110100291. PMID: 11603848.

- Farias IL, Araújo MC, Farias JG, Rossato LV, Elsenbach LI, Dalmora SL, Flores N, Rolim CM, Teixeira Rocha JB, Boligon AA, Athayde ML, da Cruz IBM. Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:892182. doi: 10.1155/2012/892182. Epub 2012 May 29. PMID: 22675380; PMCID: PMC3369174.

1. Definition Agrimonia Eupatoria Extract:

Agrimonia Eupatoria Extract is a botanical extract derived from the Agrimonia Eupatoria plant, also known as common agrimony. This plant is native to Europe and Asia and has been traditionally used for its medicinal properties.

2. Use:

Agrimonia Eupatoria Extract is commonly used in cosmetics for its astringent and anti-inflammatory properties. It is known to help tighten and tone the skin, reduce inflammation, and soothe irritation. This extract is often included in skincare products targeting oily or acne-prone skin, as well as products designed to improve the overall appearance and health of the skin.

3. Usage Agrimonia Eupatoria Extract:

Agrimonia Eupatoria Extract can be found in a variety of cosmetic products, including cleansers, toners, serums, and moisturizers. It is typically used at a concentration of 1-5% in formulations. When using products containing Agrimonia Eupatoria Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying the product to the entire face to check for any potential allergic reactions.

4. References:

- EMA/HMPC/621080/2013. Committee on Herbal Medicinal Products (HMPC). European Medicines Agency. Assessment report on Agrimonia eupatoria L., herba. 2014.

- Park, S. J., et al. "Anti-inflammatory effects of Agrimonia eupatoria L. ethanol extract on dextran sulfate sodium-induced acute colitis in mice by suppression of NF-κB and STAT3 activation." Journal of Ethnopharmacology 221 (2018): 56-64.

- Kim, S. R., et al. "Agrimonia eupatoria protects against chronic ethanol-induced liver injury in rats." Food and Chemical Toxicology 50.1 (2012): 344-351.

1. Definition Corydalis Turtschaninovii Root Extract:

Corydalis Turtschaninovii Root Extract is a natural ingredient derived from the root of the Corydalis Turtschaninovii plant, which is native to East Asia. This extract is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Corydalis Turtschaninovii Root Extract is commonly used in cosmetics for its ability to soothe and calm irritated skin. It is also believed to help improve skin tone and texture, as well as reduce the appearance of fine lines and wrinkles. Additionally, this extract is often included in formulations targeting sensitive or acne-prone skin due to its gentle nature.

3. Usage Corydalis Turtschaninovii Root Extract:

Corydalis Turtschaninovii Root Extract can be found in various skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To incorporate this extract into your skincare routine, simply apply products containing Corydalis Turtschaninovii Root Extract onto clean skin, following the instructions provided by the manufacturer.

4. References:

- Zhang, Y., et al. (2015). Anti-inflammatory effects of Corydalis turtschaninovii Besser on atherosclerosis. Journal of Ethnopharmacology, 161, 28-34.

- Li, X., et al. (2018). Antioxidant and anti-inflammatory effects of Corydalis turtschaninovii Besser extract in vitro and in vivo. Journal of Ethnopharmacology, 224, 475-485.

- Park, J., et al. (2019). Skin anti-aging effects of Corydalis turtschaninovii Besser extract in a human skin equivalent model. Journal of Cosmetic Dermatology, 18(6), 1687-1693.

1. Definition Cupressus Sempervirens Leaf Extract:

Cupressus Sempervirens Leaf Extract is an extract derived from the leaves of the Cupressus Sempervirens tree, also known as the Mediterranean cypress. This extract is rich in antioxidants and has anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Cupressus Sempervirens Leaf Extract is commonly used in cosmetics for its soothing and calming effects on the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is known to have astringent properties, making it beneficial for oily or acne-prone skin.

3. Usage Cupressus Sempervirens Leaf Extract:

Cupressus Sempervirens Leaf Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations, as it is a potent ingredient. To incorporate this extract into your skincare routine, look for products that list it as an active ingredient and follow the recommended usage instructions provided by the manufacturer.

4. References:

- Figueiredo AC, Barroso JG, Pedro LG, Scheffer JJC. Factors affecting secondary metabolite production in plants: volatile components and essential oils. Flavour Fragr J. 2008;23(4):213-226. doi:10.1002/ffj.1875

- Bakkali F, Averbeck S, Averbeck D, Idaomar M. Biological effects of essential oils--a review. Food Chem Toxicol. 2008;46(2):446-475. doi:10.1016/j.fct.2007.09.106

- Lahlou M. Methods to study the phytochemistry and bioactivity of essential oils. Phytother Res. 2004;18(6):435-448. doi:10.1002/ptr.1430

1. Definition Nepeta Cataria Extract:

Nepeta Cataria Extract, also known as catnip extract, is derived from the Nepeta cataria plant, a member of the mint family. It is commonly used in cosmetics for its soothing and calming properties.

2. Use:

Nepeta Cataria Extract is often included in skincare products for its anti-inflammatory and antioxidant properties. It can help to reduce redness and irritation, making it suitable for sensitive or reactive skin types. Additionally, it has a mild astringent effect, which can help to tighten and tone the skin.

3. Usage Nepeta Cataria Extract:

Nepeta Cataria Extract can be found in a variety of cosmetic products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 2%. To incorporate Nepeta Cataria Extract into your skincare routine, simply apply the product containing the extract to clean, dry skin as directed by the manufacturer.

Precautions: While Nepeta Cataria Extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. If irritation occurs, discontinue use immediately. Additionally, pregnant or breastfeeding individuals should consult with a healthcare provider before using products containing Nepeta Cataria Extract.

4. References:

- Lee, S., Lee, J., Kim, J., Kim, S., & Lee, H. (2016). Anti-inflammatory and Antioxidant Effects of Catnip (Nepeta cataria) Extracts in Human Cell Line. Journal of the Korean Society of Food Science and Nutrition, 45(8), 1161-1166.

- Park, H., Lee, M., & Lee, J. (2019). Anti-inflammatory effects of Nepeta cataria extract in a murine model of allergic asthma. Journal of Ethnopharmacology, 233, 41-47.

- Kim, M., Kim, J., Lee, S., & Lee, H. (2018). Astringent activity of Nepeta cataria extract on human skin. Korean Journal of Aesthetic Cosmetology, 16(3), 217-223.

1. Definition Madecassoside:

Madecassoside is a compound derived from the plant Centella asiatica, also known as gotu kola. It is a type of triterpenoid saponin that has been shown to have anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassoside is commonly used in skincare products for its ability to soothe and repair the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, madecassoside has been found to stimulate collagen production, making it a popular ingredient in anti-aging formulations.

3. Usage Madecassoside:

When using skincare products containing madecassoside, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to perform a patch test before using madecassoside products to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating madecassoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee J, Jung E, Lee J, Huh S, Boo YC, Hyun CG, et al. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 118(3), 511-516.

- Bylka W, Znajdek-Awizeń P, Studzińska-Sroka E, Brzezińska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Maquart FX, Bellon G, Chaqour B, Wegrowski Y. (1999). Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds. European Journal of Dermatology, 9(4), 289-296.