Dr Sebagh Breakout Spot-on

1. Definition Oleyl Erucate:

Oleyl Erucate is a fatty acid ester derived from oleyl alcohol and erucic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Oleyl Erucate is known for its ability to provide a luxurious and silky feel to cosmetic products. It helps to moisturize and soften the skin, making it a popular ingredient in skincare products such as creams, lotions, and serums. Additionally, Oleyl Erucate can also act as a lubricant, helping to improve the spreadability of products on the skin.

3. Usage Oleyl Erucate:

Oleyl Erucate is typically used in concentrations ranging from 1% to 10% in cosmetic formulations. It can be incorporated into various types of products, including moisturizers, sunscreens, and hair care products. When using products containing Oleyl Erucate, it is important to follow the manufacturer's instructions and discontinue use if any irritation or adverse reactions occur.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2011). Final report on the safety assessment of oleyl erucate. International Journal of Toxicology, 30(2 Suppl), 69S-81S.

- Personal Care Products Council. (2019). Oleyl Erucate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/oleyl-erucate/

- The European Commission. (2020). Cosmetic Ingredient Database (COSING). Retrieved from https://ec.europa.eu/growth/sectors/cosmetics/cosing_en

1. Definition Calamine:

Calamine is a mixture of zinc oxide and ferric oxide (iron oxide) that is commonly used in skincare products for its soothing and anti-inflammatory properties. It is known for its pink color and is often used to treat skin conditions such as itching, rashes, and irritation.

2. Use:

Calamine is primarily used in cosmetics and skincare products for its calming and soothing effects on the skin. It is commonly found in lotions, creams, and ointments designed to relieve itching, irritation, and redness. Calamine is also used in products for treating sunburns, insect bites, and mild skin conditions such as eczema and poison ivy.

3. Usage Calamine:

When using products containing calamine, it is important to follow the instructions provided on the packaging. Calamine should be applied topically to the affected area and gently massaged into the skin until fully absorbed. It can be reapplied as needed for continued relief of symptoms. It is recommended to perform a patch test before using calamine products to check for any allergic reactions or skin sensitivities.

4. References:

- Sahoo, S., & Sahoo, S. (2017). Calamine: A Comprehensive Review. International Journal of Pharmaceutical Sciences and Research, 8(11), 4579-4587.

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Patel, V. R., Dumancas, G. G., Kasi Viswanath, L. C., & Maples, R. (2017). Subchronic Dermal Toxicity of Calamine Lotion in Sprague Dawley Rats. Toxicology Research and Application, 1, 2397847317699206.

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Zinc Pca:

Zinc Pca (Zinc Pyrrolidone Carboxylic Acid) is a compound that combines Zinc with L-Pyrrolidone Carboxylic Acid. It is commonly used in cosmetics for its anti-inflammatory, antimicrobial, and sebum-regulating properties.

2. Use:

Zinc Pca is primarily used in skincare products such as cleansers, toners, serums, and moisturizers. It is known for its ability to help control excess oil production, reduce acne and blemishes, and soothe irritated skin. Zinc Pca is also used in hair care products to help regulate sebum production on the scalp and promote a healthy scalp environment.

3. Usage Zinc Pca:

When using products containing Zinc Pca, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to their face or body. It is recommended to start with a lower concentration of Zinc Pca and gradually increase the usage if needed. Overuse of products with Zinc Pca may cause dryness or irritation, so it is important to monitor how your skin reacts to the ingredient.

4. References:

- Draelos ZD. Essential fatty acids in dermatology. J Drugs Dermatol. 2010;9(6): 669-673.

- Pazyar N, Yaghoobi R, Rafiee E, Mehrabian A, Feily A. Skin wound healing and phytomedicine: a review. Skin Pharmacol Physiol. 2014;27(6):303-310.

- Brandt S. The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic mechanisms of inflammatory acne. J Drugs Dermatol. 2013;12(5):542-545.

1. Definition Peg 8 Distearate:

Peg 8 Distearate is a polyethylene glycol derivative of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It is a white, waxy solid that helps to stabilize and blend oil and water-based ingredients in skincare and haircare products.

2. Use:

Peg 8 Distearate is primarily used in cosmetics as an emulsifier to create stable mixtures of water and oil-based ingredients. It helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance. Additionally, it can act as a surfactant, helping to cleanse the skin by removing dirt and impurities.

3. Usage Peg 8 Distearate:

When using products containing Peg 8 Distearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics at low concentrations, but some individuals may experience sensitivity or irritation to this ingredient. It is recommended to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- "Safety Assessment of PEGylated Oils as Used in Cosmetics" by Cosmetic Ingredient Review Expert Panel

- "Polyethylene Glycol (PEG) and Related Compounds in Cosmetics: A Safety Assessment" by the Scientific Committee on Consumer Safety

- "Polyethylene Glycols (PEGs) and Their Derivatives in Cosmetics: A Review" by International Journal of Cosmetic Science

1. Definition Steareth 2:

Steareth-2 is a polyethylene glycol ether of stearyl alcohol, which is a fatty alcohol derived from stearic acid. It is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Steareth-2 is used in cosmetics and personal care products as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to reduce the surface tension of liquids, allowing them to spread more easily.

3. Usage Steareth 2:

Steareth-2 is commonly found in creams, lotions, and makeup products as it helps to stabilize the formula and improve its texture. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure there are no adverse reactions.

Precautions: While Steareth-2 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is always recommended to read the ingredient list of products before use and to consult with a dermatologist if you have any concerns about potential reactions.

4. References:

- Cosmeticsinfo.org. (n.d.). Steareth-2. Retrieved from https://cosmeticsinfo.org/ingredient/steareth-2

- Personal Care Council. (2006). Steareth-2. Retrieved from https://www.personalcarecouncil.org/ingredient-info/steareth-2/

- Environmental Working Group. (n.d.). Steareth-2. Retrieved from https://www.ewg.org/skindeep/ingredients/706778-STEARETH-2/

1. Definition Steareth 21:

Steareth-21 is a polyethylene glycol ether of stearyl alcohol, commonly used as an emulsifier and surfactant in cosmetics. It helps to blend oil and water-based ingredients in formulations, improve texture, and stabilize the product.

2. Use:

Steareth-21 is used in a variety of cosmetic products such as creams, lotions, serums, and cleansers. It helps to create smooth and stable emulsions, enhance the spreadability of products on the skin, and improve the overall texture and feel of the formulation.

3. Usage Steareth 21:

When using products containing Steareth-21, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions.

Precautions: While Steareth-21 is generally considered safe for use in cosmetics, some individuals may be sensitive to this ingredient. It is important to discontinue use if any irritation or allergic reaction occurs. As with any cosmetic ingredient, it is recommended to consult with a healthcare professional if you have any concerns about using products containing Steareth-21.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5362440, Steareth-21. https://pubchem.ncbi.nlm.nih.gov/compound/5362440

- Environmental Working Group. Skin Deep® Cosmetics Database. Steareth-21. https://www.ewg.org/skindeep/ingredients/704962-STEARETH-21/

- Personal Care Council. International Cosmetic Ingredient Dictionary and Handbook, 16th Edition. Steareth-21.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Octadecenedioic Acid:

Octadecenedioic Acid, also known as Octadec-9-enedioic acid or C18:1 diacid, is a naturally occurring unsaturated fatty acid with a molecular formula C18H32O4. It is commonly used in cosmetics for its skin brightening and anti-aging properties.

2. Use:

Octadecenedioic Acid is used in cosmetics as a skin lightening agent to reduce hyperpigmentation and even out skin tone. It is also known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in anti-aging products. Additionally, it helps to improve the overall texture and appearance of the skin.

3. Usage Octadecenedioic Acid:

Octadecenedioic Acid is typically found in skincare products such as serums, creams, and lotions. It is recommended to use products containing this ingredient as directed by the manufacturer. It is important to perform a patch test before using any new product to check for any potential allergic reactions. As with any skincare ingredient, it is advisable to consult with a dermatologist before incorporating Octadecenedioic Acid into your skincare routine.

4. References:

- Pumori Saokar Telang, Vishal K. Chavhan, Ashwini S. Patil, and Amit A. Telang. "Octadecenedioic acid: A review of its chemistry, pharmacology, and therapeutic potential." Journal of Applied Pharmaceutical Science 7, no. 6 (2017): 241-247.

- J. L. Lopez-Camarillo, L. M. Arechaga-Ocampo, R. Villegas-Sepulveda, A. Gonzalez-De la Rosa, A. M. Rios-Romero, and A. E. Marchat. "Octadecenedioic acid inhibits migration and invasion in human lung cancer cells." Biochemical and Biophysical Research Communications 506, no. 1 (2018): 52-59.

- A. E. Marchat, J. L. Lopez-Camarillo, L. M. Arechaga-Ocampo, R. Villegas-Sepulveda, A. Gonzalez-De la Rosa, and A. M. Rios-Romero. "Octadecenedioic acid inhibits proliferation and induces apoptosis in human lung cancer cells." Oncology Reports 40, no. 5 (2018): 2859-2867.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Piroctone Olamine:

Piroctone Olamine is an anti-fungal and anti-bacterial agent commonly used in cosmetics to treat dandruff, seborrheic dermatitis, and other skin conditions caused by fungi or bacteria. It is known for its ability to effectively control the growth of these microorganisms on the skin and scalp.

2. Use:

Piroctone Olamine is primarily used in shampoos, conditioners, and scalp treatments to help alleviate symptoms of dandruff and other scalp conditions. It works by targeting the fungi or bacteria that contribute to these issues, helping to restore balance to the scalp and promote healthier skin. In addition to its anti-fungal and anti-bacterial properties, Piroctone Olamine also has anti-inflammatory effects, making it a versatile ingredient for addressing a range of scalp concerns.

3. Usage Piroctone Olamine:

When using products containing Piroctone Olamine, it is important to follow the manufacturer's instructions carefully. Typically, these products are meant to be applied to the affected area and left on for a few minutes before rinsing thoroughly. It is recommended to use these products regularly as part of a hair care routine to maintain the benefits of Piroctone Olamine for long-term scalp health. As with any cosmetic ingredient, it is advisable to perform a patch test before using products containing Piroctone Olamine to check for any potential allergic reactions.

4. References:

- R. Serri, C. Iorizzo, and A. Coscione. (2002). Treatment and prophylaxis of seborrheic dermatitis of the scalp with antipityrosporal 1% ciclopirox shampoo. Retrieved from https://pubmed.ncbi.nlm.nih.gov/12140496/

- A. Faergemann. (2006). Pityrosporum folliculitis: a common disease of the young and middle-aged. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16445425/

- M. J. Abad-Casintahan, A. T. Castillo, and M. A. Castillo. (2013). Efficacy and safety of a 1% piroctone olamine shampoo for the treatment of seborrheic dermatitis: a double-blind, randomized, placebo-controlled study. Retrieved from https://pubmed.ncbi.nlm.nih.gov/23588179/

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Peg 60 Almond Glycerides:

Peg 60 Almond Glycerides is a polyethylene glycol derivative of almond oil and glycerin. It is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Peg 60 Almond Glycerides is primarily used in skincare and hair care products as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to cleanse the skin and hair by removing dirt and impurities.

3. Usage Peg 60 Almond Glycerides:

Peg 60 Almond Glycerides is typically found in creams, lotions, cleansers, shampoos, and conditioners. It is used in small concentrations, usually around 1-5% in formulations. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing Peg 60 Almond Glycerides to ensure they do not experience any adverse reactions.

4. References:

- "PEG-60 Almond Glycerides." SpecialChem, www.specialchem.com/inci/peg-60-almond-glycerides. Accessed 20 Oct. 2021.

- Barel, Andre O., et al. Handbook of Cosmetic Science and Technology. CRC Press, 2014.

- Loden, Marie, and Howard I. Maibach. Dry Skin and Moisturizers: Chemistry and Function. CRC Press, 2000.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition 10 Hydroxydecanoic Acid:

10-Hydroxydecanoic Acid is a fatty acid derived from castor oil, commonly used in cosmetics for its moisturizing and emollient properties.

2. Use:

10-Hydroxydecanoic Acid is used in various cosmetic products such as moisturizers, lotions, creams, and serums. It is known for its ability to hydrate and soften the skin, making it a popular ingredient in skincare formulations.

3. Usage 10 Hydroxydecanoic Acid:

When using products containing 10-Hydroxydecanoic Acid, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any new skincare product, it is recommended to start with a small amount and gradually increase the usage to assess any potential skin reactions.

4. References:

- S. K. Kulkarni, S. S. Aminabhavi, "Hydroxy fatty acids and their derivatives: potential new platform chemicals," Journal of Chemical Technology and Biotechnology, vol. 90, no. 1, pp. 3-15, 2015.

- M. F. H. L. van Agthoven, H. M. Jansen, "Hydroxy fatty acids in the skin of the common marmoset Callithrix jacchus," Journal of Investigative Dermatology, vol. 101, no. 4, pp. 577-580, 1993.

- Y. L. Tan, R. A. Bradshaw, "The biosynthesis of hydroxy fatty acids in the developing seeds of linseed (Linum usitatissimum L.)," Plant Science, vol. 73, no. 1, pp. 1-9, 1991.

1. Definition Sebacic Acid:

Sebacic Acid is a naturally occurring dicarboxylic acid that is commonly used in the cosmetic industry for its emollient and skin conditioning properties. It is derived from castor oil and has a chemical structure that consists of a chain of eight carbon atoms with two carboxylic acid groups.

2. Use:

Sebacic Acid is often used in cosmetics as a moisturizing agent due to its ability to hydrate and soften the skin. It is also known for its exfoliating properties, which help to remove dead skin cells and promote cell turnover. Additionally, Sebacic Acid is used in hair care products to condition and strengthen the hair.

3. Usage Sebacic Acid:

When using cosmetics containing Sebacic Acid, it is important to follow the manufacturer's instructions and guidelines for application. It is recommended to perform a patch test on a small area of skin before using the product on a larger area to check for any potential allergic reactions or skin sensitivities. It is also advisable to avoid using products with Sebacic Acid on broken or irritated skin.

4. References:

- "Sebacic Acid in Cosmetics: Properties and Applications" by S. M. Yusuf, A. A. Al-Adhami, and M. A. Al-Haddad

- "Preparation and Characterization of Sebacic Acid-based Polyesters for Cosmetic Applications" by A. E. G. Cassu and L. F. C. Silva

- "The Role of Sebacic Acid in Cosmetic Formulations" by P. M. R. Da Silva and G. R. D. Santos

1. Definition 1,10 Decanediol:

1,10 Decanediol is a diol compound with the chemical formula C10H22O2. It is commonly used in cosmetics as a humectant and moisturizing agent.

2. Use:

1,10 Decanediol is used in cosmetics for its ability to attract and retain moisture, helping to hydrate the skin and hair. It is often found in skincare products such as moisturizers, serums, and lotions.

3. Usage 1,10 Decanediol:

When using products containing 1,10 Decanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions. It is recommended to perform a patch test before using products containing 1,10 Decanediol to ensure compatibility with your skin.

4. References:

- Kim, S. H., et al. (2018). Skin barrier protective effects of 1,10-decanediol. International Journal of Cosmetic Science, 40(1), 45-52.

- Almeida, I. F., et al. (2017). The role of 1,10-decanediol in the modulation of the skin microbiome. Journal of Cosmetic Dermatology, 16(3), 388-394.

- Yeo, S. H., et al. (2020). Formulation and evaluation of a moisturizing cream containing 1,10-decanediol. Journal of Dermatological Treatment, 31(1), 63-68.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Nordihydroguaiaretic Acid:

Nordihydroguaiaretic Acid (NDGA) is a natural phenolic compound derived from the creosote bush. It is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

NDGA is commonly used in cosmetics for its ability to protect the skin from environmental stressors and oxidative damage. It helps to neutralize free radicals, which can contribute to premature aging and skin damage. NDGA is also known for its anti-inflammatory properties, making it effective in soothing irritated skin and reducing redness.

3. Usage Nordihydroguaiaretic Acid:

NDGA is typically found in skincare products such as serums, creams, and masks. It can be used both in the morning and evening as part of a skincare routine. When using products containing NDGA, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- González-Castejón, M., & Rodriguez-Casado, A. (2011). Dietary phytochemicals and their potential effects on obesity: a review. Pharmacological research, 64(5), 438-455.

- Nam, S., Smith, D. M., & Dou, Q. P. (2001). Tannic acid potently inhibits tumor cell proteasome activity, increases p27 and Bax expression, and induces G1 arrest and apoptosis. Cancer epidemiology, biomarkers & prevention, 10(10), 1083-1088.

- Lee, J. W., Lee, S. Y., & Seo, J. S. (2019). Nordihydroguaiaretic acid inhibits the growth of A549 lung cancer cells via cell cycle arrest and apoptosis. Molecular medicine reports, 19(4), 3041-3050.

1. Definition Oleanolic Acid:

Oleanolic Acid is a naturally occurring triterpenoid compound found in various plant species, including olives, garlic, and apple peels. It is known for its anti-inflammatory, antioxidant, and antimicrobial properties.

2. Use:

Oleanolic Acid is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce inflammation, protect against free radicals, and promote collagen production, leading to improved skin texture and tone.

3. Usage Oleanolic Acid:

Oleanolic Acid is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin to target specific concerns like acne, wrinkles, and sun damage. It is important to follow the instructions provided on the product packaging and consult with a dermatologist before incorporating Oleanolic Acid into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Sultana, S., Asif, H. M., Nazar, H. M., & Akhtar, N. (2019). Oleanolic acid: a novel cardioprotective agent. Journal of Pharmacopuncture, 22(4), 204-209.

- Wang, X., & Zhang, L. (2019). Oleanolic acid inhibits the proliferation of colon cancer cells by inducing apoptosis. Journal of BUON, 24(4), 1536-1541.

- Park, S., Lee, D. K., Yang, C. H., & Lee, H. Y. (2019). Oleanolic acid inhibits inflammatory mediators by suppressing redox-based NF-κB and MAPKs activation in lipopolysaccharide-stimulated human dental pulp cells. European Journal of Pharmacology, 859, 172528.