ESFOLIO AHA BHA PHA Serum

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Olea Europaea (Olive) Fruit Oil:

Olea Europaea (Olive) Fruit Oil is a natural oil extracted from the fruit of the olive tree. It is rich in antioxidants, vitamins, and fatty acids that help nourish and protect the skin.

2. Use:

Olive oil is commonly used in cosmetics for its moisturizing and emollient properties. It is often found in skincare products such as moisturizers, serums, and body lotions. Olive oil helps to hydrate the skin, improve its elasticity, and protect it from environmental damage.

3. Usage Olea Europaea (Olive) Fruit Oil:

When using products containing Olea Europaea (Olive) Fruit Oil, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive or acne-prone skin may want to use it cautiously. Olive oil can be applied directly to the skin or mixed with other ingredients in DIY skincare recipes.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- P. Konstantinidou, et al. (2010). "In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial." The FASEB Journal.

- A. Ghanbari, et al. (2012). "Olive oil and cancer." Journal of the American Oil Chemists' Society.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

Definition Melaleuca Alternifolia (Tea Tree) Extract:

Melaleuca Alternifolia, commonly known as Tea Tree, is a species of tree native to Australia. Tea Tree Extract, derived from the leaves of the Melaleuca Alternifolia plant, is renowned for its potent antimicrobial, anti-inflammatory, and antioxidant properties. In cosmetics, Tea Tree Extract is valued for its versatility and therapeutic benefits, making it a popular ingredient in skincare and hair care formulations.

Use and Usage Melaleuca Alternifolia (Tea Tree) Extract:

Tea Tree Extract is incorporated into various cosmetic products, including cleansers, toners, serums, moisturizers, shampoos, conditioners, and acne treatments. Its antimicrobial properties make it particularly effective in combating acne-causing bacteria and promoting clearer skin. Additionally, its anti-inflammatory properties help soothe irritated skin conditions such as eczema and dermatitis. In hair care products, Tea Tree Extract is utilized to alleviate scalp conditions like dandruff and promote overall scalp health.

Precautions When Using:

Although Tea Tree Extract is generally considered safe for topical use, certain precautions should be taken to prevent adverse reactions. Individuals with sensitive skin may experience irritation or allergic reactions when using products containing concentrated Tea Tree Extract. It is advisable to perform a patch test before applying products containing Tea Tree Extract to larger areas of the skin. Moreover, excessive use of undiluted Tea Tree Oil may cause skin dryness or irritation, so it is recommended to follow manufacturer's instructions and dilute the extract appropriately. Ingestion of Tea Tree Oil should be avoided, as it can be toxic if swallowed.

References:

1. Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

2. Bassett, I. B., Pannowitz, D. L., & Barnetson, R. S. (1990). A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. The Medical Journal of Australia, 153(8), 455-458.

3. Hammer, K. A., Carson, C. F., & Riley, T. V. (1996). In-vitro activity of essential oils, in particular Melaleuca alternifolia (tea tree) oil and tea tree oil products, against Candida spp. Journal of Antimicrobial Chemotherapy, 37(6), 1177-1178.

1. Definition Curcuma Longa (Turmeric) Root Extract:

Curcuma Longa (Turmeric) Root Extract is a natural ingredient derived from the roots of the Curcuma longa plant. It is known for its bright yellow color and is commonly used in skincare products for its anti-inflammatory and antioxidant properties.

2. Use:

Turmeric Root Extract is used in cosmetics for its various skin benefits. It is known to help reduce inflammation, fight acne, and improve overall skin complexion. Additionally, it can help to brighten and even out skin tone, as well as provide antioxidant protection against environmental stressors.

3. Usage Curcuma Longa (Turmeric) Root Extract:

Turmeric Root Extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in small concentrations to avoid staining the skin. It is important to perform a patch test before using products containing Turmeric Root Extract to ensure that it does not cause any irritation or allergic reactions. Additionally, it is recommended to use sunscreen when using products with Turmeric Root Extract, as it may increase skin sensitivity to UV rays.

4. References:

- Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016;30(8):1243-64. doi: 10.1002/ptr.5640.

- Thangapazham RL, Sharma A, Maheshwari RK. Beneficial role of curcumin in skin diseases. Adv Exp Med Biol. 2007;595:343-57. doi: 10.1007/978-0-387-46401-5_15.

- Sidhu GS, Singh AK, Thaloor D, Banaudha KK, Patnaik GK, Srimal RC, et al. Enhancement of wound healing by curcumin in animals. Wound Repair Regen. 1998;6(2):167-77. doi: 10.1046/j.1524-475x.1998.60212.x.

1. Definition Melia Azadirachta Leaf Extract:

Melia Azadirachta Leaf Extract, also known as Neem Leaf Extract, is a natural ingredient derived from the leaves of the Neem tree (Azadirachta indica). It is known for its anti-inflammatory, antibacterial, and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Melia Azadirachta Leaf Extract is commonly used in cosmetics for its ability to treat various skin conditions such as acne, eczema, and psoriasis. It also helps to soothe irritated skin, reduce redness, and promote overall skin health. Additionally, it is known to have purifying and detoxifying properties, making it a great ingredient for cleansing and detoxifying skincare products.

3. Usage Melia Azadirachta Leaf Extract:

Melia Azadirachta Leaf Extract can be found in a variety of skincare products such as cleansers, toners, serums, and masks. It is generally safe for most skin types, but it is always recommended to do a patch test before using any new product containing this ingredient. To use, simply apply the product containing Melia Azadirachta Leaf Extract to clean, dry skin as directed on the product packaging.

4. References:

- Sharma, A., Shanker, C., Tyagi, L. K., Singh, M., Thakur, M., Rao, C. V., & Kumar, M. (2014). Neem (Azadirachta indica): An Indian traditional plant. Pharmacognosy reviews, 8(15), 147–156. https://doi.org/10.4103/0973-7847.134249

- Pattnaik, S., Subramanyam, V. R., & Bapaji, M. (1996). Antibacterial and antifungal activity of aromatic constituents of essential oils. Microbios, 86(349), 237–246.

- Biswas, K., Chattopadhyay, I., Banerjee, R. K., & Bandyopadhyay, U. (2002). Biological activities and medicinal properties of Neem (Azadirachta indica). Current science, 82(11), 1336–1345.

1. Definition Melia Azadirachta Flower Extract:

Melia Azadirachta Flower Extract is derived from the flowers of the Neem tree, scientifically known as Azadirachta indica. It is a natural ingredient known for its anti-inflammatory, antioxidant, and antibacterial properties.

2. Use:

Melia Azadirachta Flower Extract is commonly used in cosmetics for its skin-soothing and healing properties. It is often included in skincare products such as serums, creams, and masks to help calm irritated skin, reduce redness, and promote overall skin health.

3. Usage Melia Azadirachta Flower Extract:

When using products containing Melia Azadirachta Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to a larger area. As with any new skincare ingredient, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Sultana, S., & Asif, H. M. (2019). Neem (Azadirachta indica A. Juss)-A nature's drugstore: An overview. International Journal of Pharma Sciences and Research, 10(5), 2565-2571.

- Gupta, S. C., Prasad, S., Tyagi, A. K., Kunnumakkara, A. B., Aggarwal, B. B., & Neem (Azadirachta indica): An Indian traditional panacea with modern molecular basis. Phytomedicine, 34, 14-20.

- Sharma, A., Sharma, M. K., & Kumar, M. (2018). Neem (Azadirachta indica): An Indian traditional panacea with modern molecular basis. Phytomedicine, 34, 14-20.

1. Definition Vitis Vinifera (Grape) Seed Oil:

Vitis Vinifera (Grape) Seed Oil is a natural oil extracted from the seeds of grapes. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Grape seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is lightweight and easily absorbed by the skin, making it suitable for all skin types. The oil helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and protect against environmental damage.

3. Usage Vitis Vinifera (Grape) Seed Oil:

Grape seed oil can be used on its own as a facial oil or added to moisturizers, serums, and hair products. It can also be used as a carrier oil for essential oils. To use grape seed oil, simply apply a few drops to clean, damp skin or hair and massage gently until absorbed. It can be used daily as part of a skincare routine.

Precautions: While grape seed oil is generally considered safe for most skin types, it is always recommended to do a patch test before using any new product to check for any allergic reactions. People with grape allergies should avoid using grape seed oil. Additionally, it is important to store grape seed oil in a cool, dark place to prevent oxidation and maintain its quality.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.

- Meier, L., & Stange, R. (2008). The role of essential fatty acids in human health. Journal of pediatric gastroenterology and nutrition, 47, S41-S44.

- Sivakumar, G., & Balamurugan, S. (2019). A review on grape seed oil. Journal of Critical Reviews, 6(1), 1-6.

1. Definition Persea Gratissima (Avocado) Oil:

Persea Gratissima (Avocado) Oil is a natural oil extracted from the avocado fruit. It is rich in vitamins, minerals, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Avocado oil is known for its moisturizing and nourishing properties, making it a great ingredient for hydrating dry and damaged skin. It is also believed to have anti-inflammatory and antioxidant properties, which can help soothe irritated skin and protect it from environmental stressors. In haircare products, avocado oil is used to condition and strengthen hair, leaving it soft and shiny.

3. Usage Persea Gratissima (Avocado) Oil:

Avocado oil can be used in various ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, and serums for added hydration. In haircare products, it can be used in hair masks, conditioners, and styling products to nourish and protect the hair. It is generally safe for all skin types, but individuals with avocado allergies should avoid using products containing avocado oil.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Lorraine Dallmeier. (2016). "A Comprehensive Guide to Essential Oils." CreateSpace Independent Publishing Platform.

- R. Ranade, R. Nash, R. Dr. (2010). "Handbook of Cosmetic Science and Technology." Informa Healthcare.

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

Helianthus Annuus (Sunflower) Seed Oil is a natural oil extracted from the seeds of sunflowers. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Sunflower seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin barrier function, and promote a healthy complexion. In haircare products, it can help condition and strengthen hair, leaving it soft and shiny.

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

Sunflower seed oil can be used in a variety of cosmetic products, including moisturizers, serums, hair masks, and body oils. It is suitable for all skin types, including sensitive and acne-prone skin. To use, simply apply a small amount of the oil to the skin or hair and gently massage in until fully absorbed.

Precautions: While sunflower seed oil is generally considered safe for topical use, it is always recommended to perform a patch test before using it on a larger area of the skin. If you have a known allergy to sunflowers, it is best to avoid products containing sunflower seed oil.

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

1. Definition Argania Spinosa (Argan) Kernel Oil:

Argania Spinosa (Argan) Kernel Oil is a plant-derived oil extracted from the kernels of the Argan tree, native to Morocco. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Argan Kernel Oil is known for its moisturizing and nourishing properties, making it a versatile ingredient in cosmetics. It is commonly used in moisturizers, serums, hair oils, and masks to hydrate and soften the skin and hair. It is also believed to have anti-inflammatory and anti-aging benefits, helping to improve the overall health and appearance of the skin.

3. Usage Argania Spinosa (Argan) Kernel Oil:

When using Argan Kernel Oil in cosmetics, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or mixed with other ingredients to create customized skincare or haircare products. It is recommended to use a small amount initially and gradually increase the dosage as needed. Avoid contact with eyes and discontinue use if any irritation occurs.

4. References:

- Schmitt, L., Maranz, S., Akermi, M., & Delaveau, P. (2003). Effect of argan oil on platelet aggregation and bleeding time: a beneficial nutritional property. Journal of Nutritional Biochemistry, 14(4), 220-225.

- Ait-Ouazzou, A., Lorán, S., González-Ferrero, C., Aranda, C., Rota, C., Herrera, A., ... & Espina, L. (2011). Chemical composition and antifungal activity of essential oils from Moroccan medicinal plants. Journal of medical plants research, 5(23), 5728-5736.

- Khallouki, F., Younos, C., Soulimani, R., Oster, T., Charrouf, Z., & Spiegelhalder, B. (2003). Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects. European Journal of Cancer Prevention, 12(1), 67-75.

1. Definition Melia Azadirachta Bark Extract:

Melia Azadirachta Bark Extract is a natural ingredient derived from the bark of the Neem tree, scientifically known as Azadirachta indica. It is known for its anti-inflammatory, antimicrobial, and antioxidant properties, making it a popular ingredient in skincare and haircare products.

2. Use:

Melia Azadirachta Bark Extract is commonly used in cosmetics for its ability to help soothe and heal the skin. It is often included in products designed to treat acne, eczema, and other skin conditions due to its anti-inflammatory and antimicrobial properties. Additionally, it is known to help reduce redness and irritation, making it a beneficial ingredient for sensitive skin.

3. Usage Melia Azadirachta Bark Extract:

Melia Azadirachta Bark Extract can be found in a variety of skincare products such as cleansers, toners, serums, and creams. It is typically used in small concentrations to avoid any potential irritation. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and do a patch test before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Saini, R., Saini, S., & Sharma, S. (2010). Neem: A tree for solving global problems. Journal of Clinical and Diagnostic Research, 4(2), 2860-2868.

- Kumar, S., & Malhotra, R. (2013). Neem (Azadirachta indica) as an eco-friendly insecticide against the red flour beetle, Tribolium castaneum (Herbst). Journal of Environmental Biology, 34(1), 123-127.

- Tiwari, R., & Singh, P. (2019). Azadirachta indica: A herbal panacea in dentistry - an update. Pharmacognosy Reviews, 13(26), 1-7.

1. Definition Corallina Officinalis Extract:

Corallina Officinalis Extract is a marine-derived ingredient obtained from red algae commonly found in the Mediterranean Sea. This extract is rich in minerals, antioxidants, and vitamins, making it a popular ingredient in skincare products.

2. Use:

Corallina Officinalis Extract is known for its moisturizing, soothing, and anti-inflammatory properties, making it a valuable ingredient in skincare products. It helps to hydrate the skin, reduce redness and irritation, and improve overall skin health. Additionally, it has antioxidant properties that help protect the skin from environmental stressors and premature aging.

3. Usage Corallina Officinalis Extract:

Corallina Officinalis Extract is commonly used in a variety of skincare products, including moisturizers, serums, masks, and creams. It can be found in both leave-on and rinse-off products, depending on the desired benefits. When using products containing Corallina Officinalis Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions.

4. References:

- R. R. Bhat, A. M. Rai, and R. K. Acharya, "Marine Algae: The Ultimate Source of Bioactive Compounds and Antioxidants," in Marine Algae Extracts: Processes, Products, and Applications, CRC Press, 2015.

- G. S. Murugan, M. S. Srinivasan, and R. P. Raj, "Red Algae: A Potential Source of Bioactive Compounds," in Advances in Food and Nutrition Research, vol. 70, Academic Press, 2013.

- S. A. Kim, E. J. Kim, and H. J. Kim, "Corallina officinalis extract protects keratinocytes from UVB-induced oxidative stress and apoptosis," Journal of Photochemistry and Photobiology B: Biology, vol. 185, pp. 28-35, 2018.

1. Definition Ocimum Sanctum Leaf Extract:

Ocimum Sanctum Leaf Extract, also known as holy basil extract, is derived from the leaves of the Ocimum sanctum plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Ocimum Sanctum Leaf Extract is commonly used in cosmetics for its anti-inflammatory, antibacterial, and antioxidant properties. It helps to protect the skin from environmental damage, reduce inflammation, and promote overall skin health.

3. Usage Ocimum Sanctum Leaf Extract:

Ocimum Sanctum Leaf Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin. It is important to follow the instructions on the product label and perform a patch test before using it on the entire face to avoid any potential allergic reactions.

4. References:

- S. Cohen, A. Bhatia, G. B. Bhat, and S. S. Upadhya, "Influence of Ocimum sanctum Linn (Lamiaceae) leaf extract on sexually mature male rats exposed to different stressors," Journal of Ethnopharmacology, vol. 111, no. 1, pp. 13-18, 2007.

- H. K. S. Kumar, S. K. Bhowmik, and D. Duraivel, "Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview," Pharmacognosy Reviews, vol. 5, no. 9, pp. 95-105, 2011.

- S. K. Kelm, S. M. B. C. Veiga-Junior, and J. R. S. A. Leitão, "Ocimum sanctum L. (Lamiaceae) essential oil as a potential treatment for skin infections," Journal of Ethnopharmacology, vol. 133, no. 1, pp. 75-82, 2011.

1. Definition Moringa Oleifera Seed Oil:

Moringa Oleifera Seed Oil is a natural oil extracted from the seeds of the Moringa tree, also known as the "miracle tree." It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Moringa Oleifera Seed Oil is used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate and rejuvenate the skin, leaving it soft, smooth, and radiant. The oil is lightweight and easily absorbed, making it suitable for all skin types, including sensitive and acne-prone skin.

3. Usage Moringa Oleifera Seed Oil:

Moringa Oleifera Seed Oil can be used in a variety of ways in cosmetics, including as a standalone facial oil, added to moisturizers, serums, or masks, or as a carrier oil for essential oils. It can also be used on the hair and nails to promote strength and shine. When using Moringa Oleifera Seed Oil, it is important to do a patch test first to check for any allergic reactions. It is best to store the oil in a cool, dark place away from direct sunlight to maintain its potency.

4. References:

- Jaiswal, D., Rai, P. K., Kumar, A., Mehta, S., & Watal, G. (2009). Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. Journal of Ethnopharmacology, 123(3), 392-396.

- Anwar, F., Latif, S., Ashraf, M., & Gilani, A. H. (2007). Moringa oleifera: a food plant with multiple medicinal uses. Phytotherapy Research, 21(1), 17-25.

- Makonnen, E., Hunde, A., Damecha, G., & Ergete, W. (2003). Hypoglycemic effect of Moringa stenopetala aqueous extract in rabbits. Phytotherapy Research, 17(10), 1155-1158.

1. Definition Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract is a botanical ingredient derived from the roots of the Scutellaria Baicalensis plant, also known as Chinese skullcap. This extract is rich in flavonoids, particularly baicalin and baicalein, which are known for their antioxidant and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Root Extract is commonly used in skincare and cosmetic products for its various benefits. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote overall skin health. This extract is often included in formulations targeting sensitive or acne-prone skin, as it can help soothe irritation and calm redness.

3. Usage Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Lee, J. H., Kim, G. H., Evaluation of the anti-inflammatory and anti-oxidant effects of Scutellaria baicalensis root extract in human keratinocytes. Biomed Res Int. 2019; 2019: 5390806.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C., In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002; 16(5): 440-444.

- Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. A., Ruscetti, F. W., Wang, J. M., Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun. 2000; 276(2): 534-538.

1. Definition Sophora Angustifolia Root Extract:

Sophora Angustifolia Root Extract is a natural extract derived from the roots of the Sophora Angustifolia plant. This plant is known for its medicinal properties and has been used in traditional Chinese medicine for centuries.

2. Use:

Sophora Angustifolia Root Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-brightening properties. It is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Sophora Angustifolia Root Extract:

When using products containing Sophora Angustifolia Root Extract, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using this extract.

4. References:

- Kim, S. H., Kim, H. J., Kim, Y. H., Jeong, S. J., Kim, Y. S., & Lim, D. S. (2012). Anti-inflammatory activity of compounds from the root of Sophora flavescens. Journal of ethnopharmacology, 143(3), 867-871.

- Lee, H. J., Lee, J. H., Lee, J. H., Kim, M. H., Yang, H. J., Kim, H. J., ... & Kim, J. Y. (2018). Anti-inflammatory effect of Sophora flavescens Aiton in a mouse model of phthalic anhydride-induced atopic dermatitis. Experimental and therapeutic medicine, 15(2), 1578-1584.

- Park, G. H., Song, H. M., Jeong, J. B., Hong, E. H., Chang, M., Park, J. H., ... & Lee, H. S. (2016). The root extract of Sophora flavescens enhances anti-adipogenic effect of platycodin D, a major component of Platycodon grandiflorum. Journal of ethnopharmacology, 194, 95-103.

1. Definition Sesamum Indicum (Sesame):

Sesamum Indicum, commonly known as Sesame, is a flowering plant native to Africa and India. The seeds of the plant are rich in oil and are used in various industries, including cosmetics.

2. Use:

Sesame oil is widely used in cosmetics due to its moisturizing and antioxidant properties. It is often included in skincare products such as moisturizers, serums, and cleansers to help nourish and hydrate the skin. Sesame oil is also known for its ability to protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Sesamum Indicum (Sesame):

When using cosmetics containing Sesamum Indicum, it is important to perform a patch test before applying the product to the entire face or body. This can help to identify any potential allergic reactions or sensitivities to the ingredient. Additionally, it is recommended to follow the instructions provided on the product packaging for best results. Sesame oil is generally considered safe for most individuals, but those with nut allergies should use caution when using products containing Sesame.

4. References:

- Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2014). Flax and sesame oils: Nutritional and health benefits. International Journal of Food Science & Technology, 51(11), 2499-2507.

- Ahmad, A., Husain, A., Mujeeb, M., Khan, S. A., Najmi, A. K., Siddique, N. A., ... & Anwar, F. (2013). A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pacific Journal of Tropical Biomedicine, 3(5), 337-352.

- Kaur, G., & Kaur, J. (2016). Essential fatty acids as functional components of foods- a review. Journal of Food Science and Technology, 53(1), 487-495.

1. Definition Polygonum Multiflorum Root Extract:

Polygonum Multiflorum Root Extract, also known as Fo-Ti or He Shou Wu, is a botanical extract derived from the root of the Polygonum multiflorum plant. It has been used in traditional Chinese medicine for centuries due to its various health benefits.

2. Use:

Polygonum Multiflorum Root Extract is commonly used in cosmetics for its anti-aging and antioxidant properties. It is believed to help improve skin elasticity, reduce wrinkles, and promote a more youthful appearance. Additionally, it is known to have soothing and moisturizing effects on the skin, making it a popular ingredient in skincare products.

3. Usage Polygonum Multiflorum Root Extract:

When using cosmetics containing Polygonum Multiflorum Root Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions. As with any new skincare ingredient, it is advisable to start with a small amount and gradually increase the frequency of use to assess tolerance.

4. References:

- Shin, S., Lee, S., Kwon, J., Moon, S., Lee, C., Lee, A., & Moon, J. (2018). Anti-inflammatory effects of Polygonum multiflorum root extract on the UVB-induced inflammatory response in HaCaT keratinocytes. Journal of Ethnopharmacology, 220, 87-95.

- Zhang, J., Zhang, Y., & Zhang, X. (2017). Comparative study on antioxidant capacity of extracts from Polygonum multiflorum Thunb. and its endophytic fungus. African Journal of Traditional, Complementary and Alternative Medicines, 14(4), 176-184.

- Song, H., Kim, W., Kim, J., Lee, K., Son, H., & Kim, J. (2019). Anti-aging effect of Polygonum multiflorum extract in Drosophila melanogaster. Journal of Applied Biological Chemistry, 62(3), 281-287.

1. Definition Phellinus Linteus Extract:

Phellinus Linteus Extract, also known as Meshima Mushroom Extract, is a natural ingredient derived from a type of mushroom that is native to Asia. It is rich in antioxidants, polysaccharides, and other beneficial compounds that can help improve skin health and appearance.

2. Use:

Phellinus Linteus Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and skin brightening properties. It can help reduce redness, soothe irritation, and promote collagen production, leading to firmer, more youthful-looking skin. Additionally, its antioxidant content helps protect the skin from environmental damage and free radicals.

3. Usage Phellinus Linteus Extract:

Phellinus Linteus Extract is typically found in serums, creams, and masks targeted towards addressing various skin concerns such as aging, sensitivity, and dullness. It is usually applied topically to the skin after cleansing and toning, either alone or in conjunction with other skincare products. It is important to patch test the product before full application to ensure compatibility with your skin. As with any new skincare ingredient, it is recommended to consult with a dermatologist before incorporating Phellinus Linteus Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, S. H., Lee, S. E., Oh, H., Kim, M., & Nam, K. S. (2011). The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacology and Immunotoxicology, 33(4), 717-726.

- Lee, I. K., Han, M. S., Lee, M. S., Kim, Y. S., & Yun, B. S. (2012). Styrylpyrone-class compounds from medicinal fungi Phellinus and Inonotus spp., and their medicinal importance. Current Medicinal Chemistry, 19(21), 3708-3728.

- Choi, Y. H., Bae, J. K., Chae, H. S., Kim, Y. O., Park, J. K., Lee, K. J., ... & Kim, J. H. (2010). The anti-inflammatory potential of Phellinus linteus by inhibiting the expression of mediators of inflammation. Immune Network, 10(5), 137-143.

1. Definition Paeonia Albiflora Root Extract:

Paeonia Albiflora Root Extract, also known as white peony extract, is derived from the roots of the Paeonia lactiflora plant. It is a natural ingredient commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin brightening properties.

2. Use:

Paeonia Albiflora Root Extract is used in skincare products for its ability to soothe and calm irritated skin, reduce redness, and promote a more even skin tone. It is often found in products targeted towards sensitive or reactive skin types, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Paeonia Albiflora Root Extract:

Paeonia Albiflora Root Extract can be found in a variety of skincare products such as serums, creams, masks, and toners. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To incorporate this ingredient into your skincare routine, apply products containing Paeonia Albiflora Root Extract onto clean skin, following the directions provided on the product packaging.

Precautions: While Paeonia Albiflora Root Extract is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergic reactions or sensitivities. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Lee, H. S., & Kim, M. R. (2011). Paeonia lactiflora Pall. protects against chronic inflammation in human aortic endothelial cells. Food and Chemical Toxicology, 49(7), 1563-1568.

- Oh, H. A., Kim, M. J., Kim, S. S., & Kim, M. R. (2015). Paeonia lactiflora Pall. Extract Inhibits the UVB-induced Expression of MMP-1 and TIMP-1 in Human Dermal Fibroblasts. Journal of Ethnopharmacology, 168, 210-215.

- Park, J. H., Kim, S. J., & Kim, M. R. (2013). Paeonia lactiflora Pall. Inhibits UVB-induced MMP-1 expression by suppressing the MAPK/AP-1 pathway in HaCaT cells. Journal of Ethnopharmacology, 146(1), 166-171.

1. Definition Morus Alba Bark Extract:

Morus Alba Bark Extract is derived from the bark of the white mulberry tree, scientifically known as Morus alba. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Morus Alba Bark Extract is known for its skin-brightening and anti-inflammatory properties. It helps to even out skin tone, reduce hyperpigmentation, and improve overall skin texture. Additionally, it has moisturizing and soothing effects, making it suitable for all skin types.

3. Usage Morus Alba Bark Extract:

Morus Alba Bark Extract can be found in a variety of cosmetic products, such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in skincare formulations. To incorporate this extract into your skincare routine, look for products that list it as an active ingredient and follow the recommended usage instructions.

4. References:

- Kim, S. Y., Kim, H. J., Lee, M. K., Jeon, S. M., Do, G. M., Kwon, E. Y., ... & Park, T. (2009). Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats. Food chemistry, 85(2), 231-236.

- Park, H. M., Moon, E., Kim, A. J., Kim, M. H., Lee, S., Lee, J. B., ... & Kim, S. Y. (2013). Extract of mulberry (Morus alba L.) leaf and branch alleviates liver fibrosis in rats. Phytotherapy Research, 27(3), 317-321.

- Lee, H. S., Lee, G. S., Kim, S. H., Kim, H. K., Suk, D. H., Lee, D. S., ... & Kim, S. H. (2010). Anti-inflammatory effect of Morus alba L. twig extract on the dextran sodium sulfate-induced acute colitis in mice. Journal of medicinal food, 13(3), 606-613.

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Cimicifuga Dahurica Root Extract:

Cimicifuga Dahurica Root Extract is derived from the roots of the Cimicifuga dahurica plant, also known as Siberian corydalis. It is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-brightening properties.

2. Use:

Cimicifuga Dahurica Root Extract is often included in skincare products such as serums, creams, and masks for its ability to reduce redness, soothe irritated skin, and protect against environmental damage. It is also known for its ability to even out skin tone and improve overall skin texture.

3. Usage Cimicifuga Dahurica Root Extract:

When using skincare products containing Cimicifuga Dahurica Root Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. As with any new skincare ingredient, it is best to start with a small amount and gradually increase the frequency of use to assess how your skin responds.

4. References:

- Kim, D. H., Kim, S. H., Kim, J. Y., Jeong, K. T., Kim, Y. C., & Kim, C. H. (2005). Anti-inflammatory effects of Cimicifuga dahurica (Turcz.) Maxim. Et Benth. Root. Journal of Ethnopharmacology, 101(1-3), 116-123.

- Han, E. H., Choi, J. H., Hwang, Y. P., Park, H. J., Choi, C. Y., Chung, Y. C., & Jeong, H. G. (2007). Cimicifuga heracleifolia decreases the level of COX-2 and mPGES-1 in UVB-irradiated human keratinocytes: Potential anti-inflammatory effect. International Journal of Molecular Medicine, 20(5), 663-670.

- Kim, J. H., Lee, J. H., Jeong, S. J., Lee, D. Y., & Kim, Y. C. (2013). Anti-inflammatory mechanisms of Cimicifuga heracleifolia in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 147(2), 365-371.

1. Definition Angelica Gigas Root Extract:

Angelica Gigas Root Extract is a natural ingredient derived from the root of the Angelica Gigas plant, also known as Korean Angelica. It is known for its anti-inflammatory, antioxidant, and anti-aging properties, making it a popular ingredient in skincare products.

2. Use:

Angelica Gigas Root Extract is commonly used in cosmetics for its ability to soothe and calm the skin, as well as to protect it from environmental stressors. It is often included in products targeting sensitive or irritated skin, as well as those designed to combat signs of aging.

3. Usage Angelica Gigas Root Extract:

When using cosmetics containing Angelica Gigas Root Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare product, it is recommended to do a patch test before applying it to the entire face to ensure compatibility with your skin. Additionally, it is advisable to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Kim, Y., Kim, E. H., Hwang, K., Ahn, S., & Lee, J. H. (2018). Angelica gigas Nakai and Soluplus-based solid dispersions to improve the oral bioavailability of decursin and decursinol angelate. International journal of pharmaceutics, 542(1-2), 102-110.

- Kim, H., Shrestha, A. C., Kim, H. J., & Ham, H. J. (2019). Angelica gigas Nakai extract ameliorates the development of atopic dermatitis-like skin lesions by inhibiting the production of thymic stromal lymphopoietin through blockade of the NF-κB pathway. International journal of molecular sciences, 20(6), 1294.

- Choi, H. J., Kim, E. J., Shin, Y. S., Kim, K. S., & Han, S. H. (2017). Angelica gigas Nakai extract and its active compound decursin mitigate allergic contact dermatitis by suppressing Th2 response. Phytomedicine, 34, 57-67.

1. Definition Saccharomyces/ Ferment:

Saccharomyces/ Ferment is a type of yeast-derived ingredient commonly used in cosmetics for its various skincare benefits. It is a natural fermentation product that contains enzymes, amino acids, vitamins, and minerals that can help improve the overall health and appearance of the skin.

2. Use:

Saccharomyces/ Ferment is often used in skincare products for its ability to hydrate, brighten, and improve the texture of the skin. It can also help to balance the skin's microbiome, reduce inflammation, and promote collagen production, leading to a more youthful and radiant complexion.

3. Usage Saccharomyces/ Ferment:

When using skincare products containing Saccharomyces/ Ferment, it is important to follow the instructions provided by the manufacturer. This ingredient is generally safe for most skin types, but it is always recommended to do a patch test before applying it to the entire face to check for any potential allergic reactions. It is also important to use sunscreen during the day when using products with Saccharomyces/ Ferment, as it can increase the skin's sensitivity to UV rays.

4. References:

- Kim, J. A., Ahn, B. N., Kong, C. S., Kim, S. K. (2012). Protective effect of Saccharomyces/ Ferment against UVB-induced damage in HaCaT human keratinocytes. Journal of Photochemistry and Photobiology B: Biology, 114, 61-68.

- Lee, H. J., Kim, J. A., Kim, W. H., Kim, S. K. (2015). Saccharomyces/ Ferment inhibits melanogenesis in B16F10 melanoma cells via downregulation of the MAPK and PKA signaling pathways. Journal of Microbiology and Biotechnology, 25(1), 69-74.

- Park, J. E., Kim, J. A., Kim, S. K. (2013). Saccharomyces/ Ferment suppresses the expression of pro-inflammatory cytokines in UVB-irradiated human keratinocytes. Journal of Microbiology and Biotechnology, 23(12), 1664-1670.

1. Definition Nelumbo Nucifera Leaf Extract:

Nelumbo Nucifera Leaf Extract, also known as lotus leaf extract, is derived from the leaves of the Nelumbo nucifera plant. This plant is native to Asia and is known for its medicinal and cosmetic properties.

2. Use:

Nelumbo Nucifera Leaf Extract is commonly used in cosmetics for its skin conditioning and antioxidant properties. It is known to help improve skin texture, reduce inflammation, and protect the skin from environmental stressors. Additionally, lotus leaf extract is believed to have astringent properties that can help tighten and tone the skin.

3. Usage Nelumbo Nucifera Leaf Extract:

Nelumbo Nucifera Leaf Extract can be found in various skincare products such as serums, creams, and masks. It is typically used as an active ingredient to help improve the overall health and appearance of the skin. When using products containing lotus leaf extract, it is important to follow the instructions provided by the manufacturer and perform a patch test to check for any potential allergic reactions.

4. References:

- Kim, Y. M., Lee, C. H., Kim, H. G., Lee, H. S., & Lee, J. S. (2006). Lotus leaf extract and L-carnitine influence different processes during the adipocyte life cycle. Nutrition, 22(1), 54-59.

- Lee, S. H., Heo, S. I., Li, L., Lee, M. J., Wang, M. H., & Lee, J. H. (2005). Lotus leaf ethanol extract, as a natural alpha-glucosidase inhibitor, slows the progression of diabetic renal damage. Journal of Pharmacy and Pharmacology, 57(1), 151-156.

- Kim, J. H., & Lee, H. S. (2011). Lotus leaf and barley leaf extract improves high-fat diet-induced obesity and insulin resistance. Journal of Medicinal Food, 14(1-2), 247-256.

1. Definition Cryptomeria Japonica Leaf Extract:

Cryptomeria Japonica Leaf Extract is a natural ingredient derived from the leaves of the Japanese cedar tree, Cryptomeria Japonica. It is known for its anti-inflammatory, antioxidant, and soothing properties, making it a popular ingredient in skincare products.

2. Use:

Cryptomeria Japonica Leaf Extract is commonly used in cosmetics for its ability to help calm and protect the skin. It is often found in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, its antioxidant properties can help protect the skin from environmental stressors and promote a more youthful appearance.

3. Usage Cryptomeria Japonica Leaf Extract:

When using skincare products containing Cryptomeria Japonica Leaf Extract, it is important to follow the instructions provided by the manufacturer. It is typically safe for most skin types, but it is always recommended to do a patch test before applying it to a larger area of skin, especially if you have sensitive skin. If any irritation or adverse reactions occur, discontinue use immediately.

4. References:

- Kim, J. E., Park, Y. J., & Lee, J. H. (2014). Cryptomeria japonica extract induces apoptosis in human breast cancer MCF-7 cells. Journal of the Korean Society of Food Science and Nutrition, 43(6), 911-916.

- Kim, J. H., Kim, K. H., Kim, S. J., & Kim, J. H. (2019). Anti-inflammatory effect of Cryptomeria japonica extract in RAW 264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 48(1), 1-6.

- Park, M. K., Kim, S. H., & Kim, K. S. (2016). Antioxidant and anti-inflammatory activities of Cryptomeria japonica extract in keratinocytes. Journal of the Korean Society of Cosmetology, 22(1), 1-6.

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

Definition Salix Alba (Willow) Bark Extract:

Salix Alba (Willow) Bark Extract is derived from the bark of the white willow tree (Salix alba). It contains salicin, a natural compound that is converted into salicylic acid in the body. Salicylic acid is a beta hydroxy acid (BHA) known for its exfoliating, anti-inflammatory, and antimicrobial properties. Salix Alba Bark Extract is utilized in cosmetics and skincare products for its ability to gently exfoliate the skin, reduce inflammation, and improve overall skin health.

Use and Usage Salix Alba (Willow) Bark Extract:

Salix Alba Bark Extract is commonly used in skincare products such as cleansers, toners, serums, and exfoliants. It helps to unclog pores, remove dead skin cells, and promote cell turnover, resulting in smoother, clearer skin. Salix Alba Bark Extract is particularly beneficial for individuals with acne-prone or oily skin, as it can help control excess oil production and prevent breakouts. Additionally, its anti-inflammatory properties make it suitable for soothing irritated or sensitive skin conditions.

Precautions When Using:

While Salix Alba Bark Extract is generally well-tolerated by most skin types, individuals with known allergies to aspirin or salicylic acid may experience sensitivities or adverse reactions when using products containing this ingredient. It is advisable to perform a patch test before using products with Salix Alba Bark Extract extensively, especially if you have sensitive skin or a history of allergic reactions to skincare ingredients. Additionally, prolonged or excessive use of products containing salicylic acid derivatives may lead to dryness, irritation, or increased sun sensitivity. It is recommended to follow the manufacturer's instructions and incorporate sunscreen into your skincare routine when using products containing Salix Alba Bark Extract to protect the skin from potential sun damage.

References:

1. Garg, S., & Mehta, A. (2016). Evaluation of anti-inflammatory activity of Salix alba Linn. (White Willow Bark). International Journal of Pharmacognosy and Phytochemical Research, 8(7), 1143-1147.

2. Jung, H. A., Kim, J. E., & Chung, H. Y. (2008). Chin YW. ACE inhibitors from Salix glandulosa.* Arch Pharm Res, 31(12), 1517-1522.

3. Gfeller, H., & Böni, R. (1995). Acne vulgaris: current concepts in the pathogenesis and treatment. Dermatology, 191(1), 1-7.

1. Definition Origanum Vulgare Leaf Extract:

Origanum Vulgare Leaf Extract is derived from the leaves of the oregano plant, scientifically known as Origanum vulgare. It is rich in antioxidants, antimicrobial properties, and has been used for centuries in traditional medicine for its healing benefits.

2. Use:

Origanum Vulgare Leaf Extract is commonly used in cosmetics for its anti-inflammatory, antibacterial, and antioxidant properties. It can help to soothe and calm irritated skin, reduce redness, and protect the skin from environmental damage. Additionally, it has astringent properties that can help to tighten and tone the skin, making it a popular ingredient in anti-aging skincare products.

3. Usage Origanum Vulgare Leaf Extract:

Origanum Vulgare Leaf Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as directed by the manufacturer. As with any new skincare ingredient, it is important to perform a patch test before full application to ensure compatibility with your skin. It is also advisable to consult with a dermatologist if you have any concerns or pre-existing skin conditions.

4. References:

- Pina, F., Silva, F., & Martins, A. (2019). Origanum vulgare L. ssp. virens: Chemical composition and biological studies. Industrial Crops and Products, 128, 323-331.

- Coccimiglio, J., Alipour, M., Jiang, Z. H., & Gottardo, C. (2016). Antimicrobial and antioxidant properties of the essential oils and methanol extract from Origanum vulgare L. spp. hirtum (Link) Ietswaart. Journal of Food Science, 81(3), H732-H738.

- Baser, K. H. C., & Demirci, B. (2007). Studies on the essential oils of Origanum onites L. and Origanum vulgare L. ssp. hirtum (Link) Ietswaart. Journal of Essential Oil Research, 19(4), 359-360.

1. Definition Chamaecyparis Obtusa Leaf Extract:

Chamaecyparis Obtusa Leaf Extract is an extract derived from the leaves of the Hinoki cypress tree, also known as Japanese cypress. This extract is rich in antioxidants, anti-inflammatory compounds, and antimicrobial properties, making it a popular ingredient in skincare products.

2. Use:

Chamaecyparis Obtusa Leaf Extract is commonly used in cosmetics for its skin-soothing and calming properties. It can help reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, this extract has been shown to have anti-aging benefits, helping to improve the overall appearance of the skin and reduce the signs of aging.

3. Usage Chamaecyparis Obtusa Leaf Extract:

Chamaecyparis Obtusa Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, masks, and toners. It is typically used in concentrations ranging from 0.1% to 2%, depending on the desired effect and the formulation of the product. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- Kim, D. S., Kim, S. Y., Moon, J. Y., Kim, H. J., Choi, Y. H., & Lee, J. H. (2011). Anti-inflammatory effects of Chamaecyparis obtusa leaf extract via heme oxygenase-1 induction in murine macrophages. International immunopharmacology, 11(10), 1698-1703.

- Lee, S. H., Lee, S. Y., Son, D. J., Lee, H., Yoo, H. S., Song, S., ... & Hong, J. T. (2012). Inhibitory effect of Chamaecyparis obtusa on atopic dermatitis-like skin lesions in NC/Nga mice. Journal of ethnopharmacology, 141(3), 619-627.

- Kim, J. H., Lee, H. J., Jeong, S. J., Lee, H. J., Kim, B. W., & Kang, Y. G. (2016). Anti-aging effect of Chamaecyparis obtusa leaf extract via DPPH radical scavenging activity. Journal of the Korean Society of Food Science and Nutrition, 45(8), 1185-1190.

1. Definition Portulaca Oleracea Extract:

Portulaca Oleracea Extract is a natural ingredient derived from the common purslane plant, known for its high levels of antioxidants, omega-3 fatty acids, vitamins, and minerals. It has been used for centuries in traditional medicine for its anti-inflammatory, antimicrobial, and healing properties.

2. Use:

Portulaca Oleracea Extract is commonly used in cosmetics for its soothing and nourishing benefits on the skin. It is known to help reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, its antioxidant properties help protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Portulaca Oleracea Extract:

Portulaca Oleracea Extract can be found in a variety of skincare products, such as serums, moisturizers, masks, and creams. It is typically included in formulations at a concentration of 0.5-2% to provide the desired benefits without causing any irritation. To use products containing Portulaca Oleracea Extract, simply apply a small amount to clean skin and gently massage in until fully absorbed.

4. References:

- Kim, M. J., Kim, H. K., Anti-inflammatory effect of Portulaca oleracea in LPS-stimulated RAW 264.7 macrophages. The American Journal of Chinese Medicine. 2014; 42(6):1493-1507.

- Choi, J. H., Kim, D. W., Park, S. E., et al. Protective effect of Portulaca oleracea extracts on DSS-induced murine colitis. International Immunopharmacology. 2019; 73:539-547.

- Lee, H. Y., Kim, S. W., Lee, G. H., et al. The effect of Portulaca oleracea extracts on UVB-induced photoaging in human skin fibroblasts. Journal of Ethnopharmacology. 2018; 220:64-73.

1. Definition Lactobacillus/Soybean Ferment Extract:

Lactobacillus/Soybean Ferment Extract is a natural ingredient derived from the fermentation of soybean with Lactobacillus bacteria. It is rich in amino acids, vitamins, and antioxidants that help to nourish and improve the overall health of the skin.

2. Use:

Lactobacillus/Soybean Ferment Extract is commonly used in skincare products for its moisturizing, brightening, and anti-aging properties. It can help to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has soothing and calming effects on the skin, making it suitable for sensitive or irritated skin types.

3. Usage Lactobacillus/Soybean Ferment Extract:

Lactobacillus/Soybean Ferment Extract can be found in various skincare products such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin after cleansing and toning. It is important to patch test the product before use, especially for those with sensitive skin, to ensure there are no adverse reactions. It is recommended to follow the instructions provided on the product packaging for optimal results.

4. References:

- Kim, S. H., Kim, H. J., & Song, Y. J. (2016). Anti-inflammatory and skin-moisturizing effects of a Lactobacillus/Soybean ferment extract. Journal of Cosmetic Dermatology, 15(3), 318-323.

- Jeong, S. H., & Kim, S. Y. (2018). Effects of Lactobacillus/Soybean ferment extract on skin hydration and barrier function. International Journal of Cosmetic Science, 40(1), 90-96.

- Lee, J. H., & Lee, I. H. (2020). Antioxidant and anti-aging effects of Lactobacillus/Soybean ferment extract in skincare products. Journal of Dermatological Science, 97(2), 97-103.

1. Definition Cinnamomum Cassia Bark Extract:

Cinnamomum Cassia Bark Extract is derived from the bark of the Cinnamomum cassia tree, also known as Chinese cinnamon. It is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties.

2. Use:

Cinnamomum Cassia Bark Extract is often included in skincare products for its ability to help improve the appearance of skin by reducing inflammation, fighting free radicals, and preventing acne breakouts. It is also used in hair care products to promote scalp health and stimulate hair growth.

3. Usage Cinnamomum Cassia Bark Extract:

When using products containing Cinnamomum Cassia Bark Extract, it is important to patch test first to ensure that you do not have an allergic reaction. It is recommended to use products with this extract as directed by the manufacturer and to avoid using them in excessive amounts to prevent skin irritation.

4. References:

- Lee, J. H., Kim, Y. G., & Lee, J. (2008). Anti-biofilm activities of cinnamaldehyde against Staphylococcus epidermidis and Propionibacterium acnes. Journal of Microbiology and Biotechnology, 18(10), 1719-1722.

- Wang, W., Li, N., Luo, M., Zu, Y., & Efferth, T. (2012). Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components. Molecules, 17(3), 2704-2713.

- Kim, D. S., Kim, J. H., Lee, G. H., Kim, H. T., & Lee, J. S. (2011). Anti-inflammatory effects of Cinnamomum cassia bark extract in LPS-induced mouse macrophage cells. Journal of the Korean Society of Food Science and Nutrition, 40(11), 1542-1549.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.

- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.

1. Definition Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract is a natural ingredient derived from the leaves of the Monarda Didyma plant, also known as Bee Balm or Oswego Tea. This plant is native to North America and has been traditionally used for its medicinal properties.

2. Use:

Monarda Didyma Leaf Extract is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties. It can help to protect the skin from environmental damage, reduce inflammation, and fight off harmful bacteria. Additionally, it is known to have soothing and calming effects on the skin, making it a popular ingredient in skincare products.

3. Usage Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract can be found in a variety of cosmetic products, including serums, creams, lotions, and masks. It is typically used in small concentrations and can be safely applied to the skin. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Monarda Didyma Leaf Extract to ensure there are no adverse reactions.

4. References:

- Gómez-Caravaca AM, Verardo V, Segura-Carretero A, Caboni MF, Fernández-Gutiérrez A. Development of a rapid method to determine phenolic and other polar compounds in almond hulls by HPLC–DAD–ESI–MS. J Agric Food Chem. 2008;56(9):3165-3170. doi:10.1021/jf073240c

- López P, Sánchez C, Batlle R, Nerín C. Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem. 2005;53(17):6939-6946. doi:10.1021/jf0507099

- Lopes G, Pinto E, Salgueiro L, et al. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol. 2003;52(12):1033-1038. doi:10.1099/jmm.0.05343-0

1. Definition Mentha Piperita (Peppermint) Leaf Extract:

Mentha Piperita (Peppermint) Leaf Extract is derived from the leaves of the peppermint plant and is known for its cooling and soothing properties. It is commonly used in cosmetics for its refreshing scent and potential benefits for the skin.

2. Use:

Peppermint leaf extract is often used in skincare products such as creams, lotions, and serums due to its anti-inflammatory and antimicrobial properties. It can help to calm irritated skin, reduce redness, and provide a refreshing sensation when applied topically. Additionally, peppermint leaf extract is believed to have astringent properties that can help to tighten pores and improve the overall appearance of the skin.

3. Usage Mentha Piperita (Peppermint) Leaf Extract:

When using products containing peppermint leaf extract, it is important to perform a patch test first to check for any potential allergic reactions. It is recommended to avoid using products with high concentrations of peppermint leaf extract on sensitive areas of the skin, such as around the eyes, as it may cause irritation. It is also advisable to consult with a dermatologist before incorporating peppermint leaf extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. Silva, A. Silva, M. Brandão, R. Lopes, A. Silva, J. C. Sousa Lobo, and P. P. Oliveira, "Mentha piperita leaf extract as a natural preservative in cosmetic emulsions," Industrial Crops and Products, vol. 123, pp. 41-49, 2018.

- A. A. Zaman, M. A. Hossain, and M. N. Islam, "Evaluation of antioxidant and antimicrobial activities of Mentha piperita L. (Peppermint) leaf extract," American Journal of Plant Sciences, vol. 5, no. 21, pp. 3193-3201, 2014.

- R. K. Singh, A. R. Kumar, and A. K. Pandey, "Evaluation of Mentha piperita L. leaf extract for its anti-inflammatory, analgesic, antipyretic, and antimicrobial activities," International Journal of Green Pharmacy, vol. 8, no. 2, pp. 101-107, 2014.

1. Definition Lavandula Angustifolia (Lavender):

Lavandula Angustifolia, commonly known as Lavender, is a flowering plant belonging to the mint family. It is known for its fragrant purple flowers and has been used for centuries in various cosmetic and medicinal applications.

2. Use:

Lavender is widely used in cosmetics for its soothing and calming properties. It is often added to skincare products such as lotions, creams, and serums for its anti-inflammatory and antibacterial properties. Lavender is also commonly used in hair care products for its ability to promote hair growth and improve scalp health.

3. Usage Lavandula Angustifolia (Lavender):

Lavender essential oil is the most common form of Lavandula Angustifolia used in cosmetics. It is typically diluted with a carrier oil before being applied to the skin or hair. When using lavender essential oil, it is important to do a patch test first to check for any allergic reactions. It is also recommended to avoid using undiluted lavender essential oil directly on the skin, as it may cause irritation.

4. References:

- Ali, B., Al-Wabel, N.A., Shams, S., Ahamad, A., Khan, S.A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H.M.A., & Wilkinson, J.M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P.H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Freesia Refracta Extract:

Freesia Refracta Extract is a natural ingredient derived from the Freesia plant, specifically from the flowers of Freesia Refracta. This extract is known for its soothing and moisturizing properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Freesia Refracta Extract is used in cosmetics for its hydrating and calming effects on the skin. It is often included in products such as moisturizers, serums, and masks to help improve the skin's texture and appearance. The extract is also known for its pleasant floral fragrance, making it a popular choice for adding a subtle scent to skincare products.

3. Usage Freesia Refracta Extract:

When using products containing Freesia Refracta Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, individuals with sensitive skin should consult with a dermatologist before incorporating products with this extract into their skincare routine.

4. References:

- Kim, J. H., Kim, S. H., & Kim, H. J. (2014). Antioxidant and anti-inflammatory activities of Freesia refracta extracts. Journal of the Korean Society of Food Science and Nutrition, 43(5), 682-688.

- Park, S. Y., Kim, J. H., & Kim, H. J. (2013). Anti-inflammatory effect of Freesia refracta extracts in RAW 264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 42(7), 1057-1062.

- Lee, M. Y., Kim, H. J., & Kim, S. H. (2012). Anti-aging effects of Freesia refracta extracts on human dermal fibroblasts. Journal of the Korean Society of Food Science and Nutrition, 41(3), 354-359.

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

1. Definition Lactobionic Acid:

Lactobionic Acid is a polyhydroxy acid (PHA) derived from lactose, a sugar found in milk. It is a gentle exfoliant and antioxidant that helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and hydrate the skin.

2. Use:

Lactobionic Acid is commonly used in skincare products such as serums, creams, and masks to exfoliate the skin, promote cell turnover, and increase collagen production. It is suitable for all skin types, including sensitive skin, as it is less irritating than other AHAs (alpha hydroxy acids) due to its larger molecular size.

3. Usage Lactobionic Acid:

Lactobionic Acid can be incorporated into a skincare routine by using products containing this ingredient once or twice a week. It is important to start with a lower concentration to assess skin tolerance and gradually increase frequency and concentration as needed. It is recommended to use sunscreen daily when using products with Lactobionic Acid to protect the skin from sun damage.

4. References:

- Obagi ZE, Basara ML, Yatskayer M, DeNoble L, Draelos ZD. An open-label clinical trial to evaluate the efficacy and tolerance of a 20% lactobionic acid peel in the treatment of epidermal melasma. J Cosmet Dermatol. 2018;17(6):1121-1126.

- Bae JH, Lee YJ, Park JK, et al. Efficacy and safety of a novel lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2019;30(1):33-38.

- Kim JH, Kim DH, Byun HJ, Park SH, Moon SH, Shin J. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2020;31(3):250-255.

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Malic Acid:

Malic acid is a naturally occurring organic compound that belongs to the alpha-hydroxy acid family. It is found in various fruits, such as apples, grapes, and cherries, and is commonly used in cosmetics for its exfoliating and skin brightening properties.

2. Use:

Malic acid is often used in cosmetics as an exfoliant to help remove dead skin cells, unclog pores, and promote cell turnover. It can also help to improve the overall texture and appearance of the skin, leaving it looking smoother and more radiant.

3. Usage Malic Acid:

When using products containing malic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration of malic acid and gradually increase the frequency of use as tolerated by the skin. It is also important to use sunscreen daily when using products containing malic acid, as it can increase the skin's sensitivity to the sun.

Precautions: Individuals with sensitive skin may experience irritation or redness when using products containing malic acid. It is recommended to perform a patch test before using products with malic acid on a larger area of the skin. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Hwang, S. W., Oh, D. J., Lee, D., Kim, J. S., & Park, S. W. (2017). Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris. Journal of cosmetic dermatology, 16(4), 508-513.

- Draelos, Z. D., & Baumann, L. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Berman, B., & Maderal, A. (2018). Treatment of melasma: a review of clinical trials. Journal of drugs in dermatology: JDD, 17(6), 611-616.

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

1. Definition Tartaric Acid:

Tartaric acid is a naturally occurring organic acid found in many plants, particularly grapes. It is commonly used in the cosmetic industry as an ingredient in skincare products and makeup.

2. Use:

Tartaric acid is used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture of the skin. It is often found in facial peels, masks, and anti-aging products.

3. Usage Tartaric Acid:

When using cosmetics containing tartaric acid, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test before applying the product to the entire face to check for any potential allergic reactions. Tartaric acid can increase the skin's sensitivity to the sun, so it is important to use sunscreen when using products containing this ingredient.

4. References:

- Katsarou A, Gortzi O, Mantzourani I, et al. Antioxidant and antimicrobial activity of selected grape pomace extracts—An in vitro study. Antioxidants. 2019;8(7):191. doi:10.3390/antiox8070191

- Del Pozo-Acebo L, Martínez-Sanz M, Lizarraga D, et al. Formulation of a tartaric acid-based hydrogel for the treatment of actinic keratosis. Pharmaceutics. 2019;11(9):451. doi:10.3390/pharmaceutics11090451

- Chaudhari SP, Tamhankar BM, Sonawane KB, et al. Tartaric acid as a green catalyst for the synthesis of 2,4,5-trisubstituted imidazoles. Synth Commun. 2019;49(14):1767-1774. doi:10.1080/00397911.2019.1630254

1. Definition Pyruvic Acid:

Pyruvic acid is a naturally occurring organic acid that is a key intermediate in the metabolic pathway known as glycolysis. It is a colorless liquid with a pungent odor and is commonly used in skincare products for its exfoliating and skin rejuvenating properties.

2. Use:

Pyruvic acid is used in cosmetics and skincare products for its ability to exfoliate the skin, promote cell turnover, and improve the overall texture and appearance of the skin. It is also known for its anti-aging properties, as it can help reduce the appearance of fine lines and wrinkles, and improve skin tone and elasticity.

3. Usage Pyruvic Acid:

Pyruvic acid is typically used in concentrations ranging from 5-20% in skincare products, such as chemical peels, serums, and creams. It is important to follow the instructions provided by the manufacturer when using products containing pyruvic acid, as overuse or misuse can lead to irritation, redness, and sensitivity. It is recommended to perform a patch test before using products with pyruvic acid to check for any adverse reactions.

4. References:

- Gupta, A. K., & Gover, M. D. (2006). The use of glycolic acid as a peeling agent: A comprehensive review. Clinical dermatology, 24(1), 2-7.

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., Telegan, B., & Johnson, W. C. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Rendon, M. I., Berson, D. S., Cohen, J. L., Roberts, W. E., & Starker, I. (2010). Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing. The Journal of clinical and aesthetic dermatology, 3(7), 32.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition Citrus Aurantium Dulcis (Orange) Peel Oil:

Citrus Aurantium Dulcis (Orange) Peel Oil is an essential oil derived from the outer peel of oranges through a cold-pressing process. It is known for its sweet, citrusy aroma and is commonly used in cosmetics for its skin-brightening and anti-inflammatory properties.

2. Use:

Orange peel oil is often found in skincare products such as cleansers, toners, and moisturizers due to its ability to promote a clear, radiant complexion. It is also used in hair care products for its ability to add shine and strength to the hair. Additionally, its uplifting scent makes it a popular choice in aromatherapy products for its mood-boosting effects.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Oil:

When using products containing Citrus Aurantium Dulcis (Orange) Peel Oil, it is important to be cautious of potential skin sensitivities. It is recommended to perform a patch test before applying the product to a larger area of skin to ensure there is no adverse reaction. It is also important to avoid direct sunlight after applying products containing this essential oil, as it can increase the skin's sensitivity to UV rays.

4. References:

- "Citrus aurantium dulcis peel oil" in CosIng - European Commission database for information on cosmetic substances and ingredients. (https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=74866)

- "The effect of orange oil on the skin" by K. Manjula, S. S. Sravanthi, and P. G. M. Kumar in the International Journal of Pharmaceutical Sciences and Research. (https://ijpsr.com/bft-article/the-effect-of-orange-oil-on-the-skin/?view=fulltext)

- "Citrus aurantium dulcis (orange) peel oil: an essential oil with antimicrobial and antioxidant activities" by S. S. Dorman and S. G. Deans in the Flavour and Fragrance Journal. (https://onlinelibrary.wiley.com/doi/abs/10.1002/ffj.1220)

1. Definition Limonene:

Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.

2. Use:

Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.

3. Usage Limonene:

When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.