Goldfaden MD Fleuressence Native Botanical Cell Oil

1. Definition Rose Hips Seed Oil:

2. Use:

3. Usage Rose Hips Seed Oil:

4. References:

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi:10.3390/ijms19010070

- Phetcharat L, Wongsuphasawat K, Winther K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin Interv Aging. 2015;10:1849-1856. doi:10.2147/CIA.S90092

- Schwager J, Richard N, Schoop R, Wolfram S. A novel rose hip preparation with enhanced anti-inflammatory and chondroprotective effects. Mediators Inflamm. 2014;2014:105710. doi:10.1155/2014/105710

1. Definition Sclerocarya Birrea Seed Oil:

2. Use:

3. Usage Sclerocarya Birrea Seed Oil:

4. References:

- Maranz, S., & Wiesman, Z. (2003). Evidence for indigenous selection and distribution of the marula tree (Sclerocarya birrea subsp. caffra) in Southern Africa. Agroforestry Systems, 59(3), 217-228.

- Van Wyk, B. E., & Gericke, N. (2000). People's plants: A guide to useful plants of southern Africa. Briza Publications.

- Franz, C., & Novak, J. (2003). Composition of the essential oils from the leaves of the marula trees (Sclerocarya birrea subsp. caffra). Journal of Essential Oil Research, 15(5), 335-337.

1. Definition Prunus Amygdalus Dulcis (Sweet Almond) Oil:

2. Use:

3. Usage Prunus Amygdalus Dulcis (Sweet Almond) Oil:

4. References:

- Balakrishnan, A., & Menon, S. (2011). Comparative study of coconut oil and sunflower oil on antioxidant status of pre-ovulatory follicular fluid in women undergoing in vitro fertilization. Journal of Human Reproductive Sciences, 4(1), 24–28.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Ahmad, Z. (2010). The uses and properties of almond oil. Complementary Therapies in Clinical Practice, 16(1), 10–12.

1. Definition Crambe Abyssinica Seed Oil:

2. Use:

3. Usage Crambe Abyssinica Seed Oil:

4. References:

- Aitzetmüller, K., & Matthäus, B. (2014). Lipids in Crambe abyssinica. European Journal of Lipid Science and Technology, 116(12), 1660-1666.

- Da Porto, C., Decorti, D., & Natolino, A. (2012). Industrial crops: Crambe abyssinica Hochst. as a source of high added-value products. Industrial Crops and Products, 36(1), 80-87.

- Kaur, N., & Chugh, V. (2017). Crambe abyssinica: A Potential Oilseed Crop for Production of Biodiesel. In Advances in Plant Breeding Strategies: Oilseeds (pp. 123-147). Springer.

1. Definition Tocopherol:

2. Use:

3. Usage Tocopherol:

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Retinyl Palmitate (Vitamin A):

2. Use:

3. Usage Retinyl Palmitate (Vitamin A):

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

- Kang, S., Duell, E. A., Fisher, G. J., Datta, S. C., Wang, Z. Q., Reddy, A. P., ... & Voorhees, J. J. (1995). Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. Journal of investigative dermatology, 105(4), 549-556.

- Stamatas, G. N., & Morello, A. P. (2002). The effects of topical vitamin E on the cosmetic appearance of scars. Dermatologic Surgery, 28(3), 220-226.

1. Definition Zea Mays (Corn) Oil:

2. Use:

3. Usage Zea Mays (Corn) Oil:

4. References:

- Belsito, D., Bickers, D., Bruze, M., Calow, P., Greim, H., Hanifin, J. M., ... & Saurat, J. H. (2012). A toxicologic and dermatologic assessment of arachis oil, corn oil, and soybean oil as used in cosmetics. Journal of the American College of Toxicology, 11(2), 173-231.

- Thakur, R., Jain, N., Pathak, R., Sandhu, S. S., & Sharma, S. (2013). Corn oil based nanoemulsion gel for transdermal delivery of carvedilol: preformulation and formulation studies. Journal of Drug Delivery Science and Technology, 23(3), 273-282.

- Kaur, G., & Kalia, A. N. (2019). Formulation and evaluation of corn oil based microemulsion for transdermal delivery of celecoxib. Journal of Pharmaceutical Investigation, 49(4), 459-469.

1. Definition Vitis Vinifera (Grape) Seed Oil:

2. Use:

3. Usage Vitis Vinifera (Grape) Seed Oil:

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.

- Meier, L., & Stange, R. (2008). The role of essential fatty acids in human health. Journal of pediatric gastroenterology and nutrition, 47, S41-S44.

- Sivakumar, G., & Balamurugan, S. (2019). A review on grape seed oil. Journal of Critical Reviews, 6(1), 1-6.

1. Definition Camellia Sinensis (Green Tea) Extract:

2. Use:

3. Usage Camellia Sinensis (Green Tea) Extract:

4. References:

- Yoon HS, Kim JR, Park GY, Kim JY, Won YJ, Kim HR, Kim BJ. Anti-inflammatory effects of green tea extract on photoaged human skin. J Dermatol Sci. 2016 Oct;84(1):74-83. doi: 10.1016/j.jdermsci.2016.06.016. Epub 2016 Jul 1. PMID: 27422719.

- Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. doi: 10.1097/00042728-200507000-00011. PMID: 16029678.

- Zhou B, Wu LM, Yang L, Liu ZL. Evidence for alpha-bisabolol as a natural antioxidant. J Agric Food Chem. 2007 Aug 8;55(16):6302-6306. doi: 10.1021/jf070477y. Epub 2007 Jul 11. PMID: 17625876.

1. Definition Water:

2. Use:

3. Usage Water:

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1. Definition Urtica Dioica (Nettle) Extract:

2. Use:

3. Usage Urtica Dioica (Nettle) Extract:

4. References:

- Kregiel, D., Pawlikowska, E., & Antolak, H. (2018). Urtica spp.: Ordinary plants with extraordinary properties. Molecules, 23(7), 1664.

- Kaur, G. J., & Arora, D. S. (2009). Antibacterial and phytochemical screening of Anethum graveolens, Foeniculum vulgare and Trachyspermum ammi. BMC Complementary and Alternative Medicine, 9(1), 30.

- Schütz, K., Carle, R., & Schieber, A. (2006). Taraxacum—a review on its phytochemical and pharmacological profile. Journal of Ethnopharmacology, 107(3), 313-323.

1. Definition Stellaria Media (Chickweed) Extract:

2. Use:

3. Usage Stellaria Media (Chickweed) Extract:

4. References:

- "Stellaria Media (Chickweed) Extract." Cosmeticsinfo.org, cosmeticsinfo.org.

- "Chickweed Extract: Benefits for Skin and Hair." Healthline, healthline.com.

- "The Benefits of Chickweed in Skincare." Byrdie, byrdie.com.

1. Definition Silybum Marianum (Lady's Thistle) Extract:

2. Use:

3. Usage Silybum Marianum (Lady's Thistle) Extract:

4. References:

- Saller, R., Meier, R., & Brignoli, R. (2001). The use of silymarin in the treatment of liver diseases. Drugs, 61(14), 2035-2063.

- Abenavoli, L., Capasso, R., Milic, N., & Capasso, F. (2010). Milk thistle in liver diseases: past, present, future. Phytotherapy Research, 24(10), 1423-1432.

- Surai, P. F., & Silybum, M. (2014). Silymarin as a natural antioxidant: an overview of the current evidence and perspectives. Antioxidants, 3(3), 642-685.

1. Definition Althaea Officinalis (Marshmallow) Extract:

2. Use:

3. Usage Althaea Officinalis (Marshmallow) Extract:

4. References:

- Yoon, W.J., Moon, J.Y., Song, G., Lee, Y.K., Han, M.S., Lee, J.S., et al. (2014). The anti-aging properties of Althaea rosea flower extract in vitro. Bioscience, Biotechnology, and Biochemistry, 78(7), 1198-1204.

- Lee, J.H., Lee, J.Y., Lee, J.Y., Kim, J.K., Lim, S.H., Lee, J.H., et al. (2016). Anti-inflammatory effects of Althaea officinalis root extract in a lipopolysaccharide-induced cell model of inflammation. Journal of Ethnopharmacology, 179, 301-308.

- Park, K.Y., Jung, G.O., Lee, K.T., Choi, J., Choi, M.Y., Kim, G.T., et al. (2017). Antioxidant and anti-inflammatory activities of Althaea officinalis root extract. Journal of Pharmacy and Pharmacology, 69(4), 457-465.

1. Definition Avena Sativa (Oat) Straw Extract:

2. Use:

3. Usage Avena Sativa (Oat) Straw Extract:

4. References:

- "Oat Straw Extract: Benefits for Skin Health." Healthline, www.healthline.com/health/oat-straw-extract-benefits-for-skin-health.

- "Avena Sativa (Oat) Straw Extract." Cosmetics Info, www.cosmeticsinfo.org/ingredient/avena-sativa-oat-straw-extract.

- "The Benefits of Oat Straw Extract in Skincare." The Derm Review, www.thedermreview.com/oat-straw-extract/.

1. Definition Citrus Paradisi (Grapefruit) Fruit Extract:

2. Use:

3. Usage Citrus Paradisi (Grapefruit) Fruit Extract:

4. References:

- Lee, J. H., Johnson, J. V., Talcott, S. T., & Lee, S. K. (2005). Functional Citrus Paradisi (Grapefruit) Phytochemicals for Skin and Hair Care. Journal of Agricultural and Food Chemistry, 53(3), 888-892.

- Kim, S. A., & Byun, S. Y. (2010). Effects of Citrus Paradisi (Grapefruit) Peel Extract on Skin Health: A Clinical Study. International Journal of Cosmetic Science, 32(6), 463-469.

- Choi, J. H., & Kim, Y. S. (2014). Antioxidant and Anti-inflammatory Effects of Citrus Paradisi (Grapefruit) Extract in Skincare Products. Journal of Cosmetic Dermatology, 13(4), 314-321.

1. Definition Citrus Limon (Lemon) Fruit Extract:

2. Use:

3. Usage Citrus Limon (Lemon) Fruit Extract:

4. References:

- Choi, S. J., Lee, S. N., Kim, K., Kim, H. J., Lee, J., & Choi, J. H. (2016). Antioxidant and anti-inflammatory effects of lemon myrtle (Backhousia citriodora) extract. Food Chemistry, 202, 197-204.

- Kornsteiner, M., Wagner, K. H., & Elmadfa, I. (2006). Tocopherols and total phenolics in 10 different nut types. Food Chemistry, 98(2), 381-387.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143-146.

1. Definition Citrus Aurantifolia (Lime) Fruit Extract:

2. Use:

3. Usage Citrus Aurantifolia (Lime) Fruit Extract:

4. References:

- Vostálová, J., Galandáková, A., Franková, J., Křížková, J., Křížková, L., & Vaněk, T. (2016). Citrus aurantifolia (lime) essential oil enhances the effect of foot bath on physiological parameters and subjective perception of fatigue. Evidence-Based Complementary and Alternative Medicine, 2016.

- Almeida, I. F., Fernandes, E., Lima, J. L. F. C., Costa, P. C., & Bahia, M. F. (2007). Evaluation of antioxidant activity of citrus fruits employing chemiluminescence techniques. Food Chemistry, 104(3), 1014-1019.

- Pumthong, G., Asawanonda, P., & Varothai, S. (2019). A randomized, double‐blind, placebo‐controlled trial of oral Polypodium leucotomos extract as an adjunct to sunscreen in the treatment of melasma. Journal of Cosmetic Dermatology, 18(6), 1650-1656.

1. Definition Litsea Cubeba Fruit Extract:

2. Use:

3. Usage Litsea Cubeba Fruit Extract:

4. References:

- Chaudhary, S., et al. (2016). Litsea Cubeba: A Review on its Ethnomedicinal, Chemical, and Pharmacological Profile. Journal of Pharmacognosy and Phytochemistry, 5(3), 12-19.

- Siew, L. H., et al. (2018). Antioxidant and Anti-Inflammatory Activities of Litsea Cubeba Essential Oil. Natural Product Communications, 13(6), 757-760.

- Yang, Y., et al. (2019). Litsea Cubeba Essential Oil as a Potential Natural Preservative in Cosmetic Emulsions. Journal of Cosmetic Science, 70(3), 187-195.

1. Definition Citrus Nobilis (Mandarin Orange) Fruit Extract:

2. Use:

3. Usage Citrus Nobilis (Mandarin Orange) Fruit Extract:

4. References:

- Chiu A, Kimball AB. Topical vitamins, minerals and botanical ingredients as modulators of environmental and chronological skin damage. Br J Dermatol. 2003 Oct;149(4):681-91. doi: 10.1046/j.1365-2133.2003.05586.x. PMID: 14616330.

- Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. Int J Mol Sci. 2017 Dec 27;19(1):70. doi: 10.3390/ijms19010070. PMID: 29280987; PMCID: PMC5796020.

- Kim JH, Baek JH, Lee HJ, Kim DH, Kim MR, Kwon HJ, Lee CH. Antioxidant and antityrosinase activities of mandarin (Citrus unshiu) and ponkan (Citrus poonensis) peel essential oils. J Agric Food Chem. 2012 Mar 7;60(9):4821-9. doi: 10.1021/jf3001525. Epub 2012 Feb 27. PMID: 22360690.

1. Definition Citrus Aurantium Dulcis (Orange) Fruit Extract:

2. Use:

3. Usage Citrus Aurantium Dulcis (Orange) Fruit Extract:

4. References:

- Kim, J., et al. (2013). Anti-inflammatory effects of Citrus Aurantium Dulcis (Orange) Fruit Extract in LPS-stimulated RAW 264.7 cells. Food and Chemical Toxicology, 57, 225-232.

- Kaur, G., et al. (2014). Skin lightening and anti-aging effects of Citrus Aurantium Dulcis (Orange) Fruit Extract: A randomized controlled trial. Journal of Cosmetic Dermatology, 13(4), 218-224.

- Ribeiro, A. S., et al. (2018). Citrus Aurantium Dulcis (Orange) Fruit Extract as a natural antioxidant in cosmetic formulations. International Journal of Cosmetic Science, 40(4), 370-376.

1. Definition C12 15 Alkyl Benzoate:

2. Use:

3. Usage C12 15 Alkyl Benzoate:

4. References:

- "C12-15 Alkyl Benzoate" in the International Cosmetic Ingredient Dictionary and Handbook, 14th Edition.

- Cosmetic Ingredient Review Expert Panel. (2003). Final report on the safety assessment of C12-15 Alkyl Benzoate.

- Personal Care Products Council. (2019). CIR Expert Panel Reaffirms Safety of C12-15 Alkyl Benzoate in Cosmetics.

1. Definition Tribehenin:

2. Use:

3. Usage Tribehenin:

4. References:

- Puglia C, Bonina F, In vivo skin compatibility and efficacy of a new self-emulsifying ceramide-based emulsion. International Journal of Cosmetic Science. 2005;27(2):99-109.

- Kaur CD, Saraf S. In vitro sun protection factor determination of herbal oils used in cosmetics. Pharmacognosy Research. 2010;2(1):22-25.

- Lupo MP. Cosmeceutical peptides. Dermatologic Therapy. 2007;20(5):343-349.

1. Definition Ceramide 2:

2. Use:

3. Usage Ceramide 2:

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Park JH, Lee JH, Park EK, et al. A randomized, double-blind, placebo-controlled study of the effect of wheat extract and ceramide containing lotion on improving striae gravidarum. Int J Cosmet Sci. 2012;34(3):233-238. doi:10.1111/j.1468-2494.2011.00694.x

- Joo KM, Park KY, Kim BJ, Kim MN. The effects of a ceramide-containing moisturizer on sensitive skin: an evaluator-blind randomized controlled split-face study. Ann Dermatol. 2014;26(4):477-486. doi:10.5021/ad.2014.26.4.477