isoi Bulgarian Rose Waterfull Cream Light

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition Calendula Officinalis (Pot Marigold) Flower Extract:

Calendula Officinalis (Pot Marigold) Flower Extract is a botanical extract derived from the flowers of the Calendula Officinalis plant. It is known for its soothing and healing properties and is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Calendula Officinalis Flower Extract is used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often found in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Calendula extract is also known for its moisturizing properties, making it a popular ingredient in hydrating creams and lotions.

3. Usage Calendula Officinalis (Pot Marigold) Flower Extract:

When using products containing Calendula Officinalis Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed, daisies, and chrysanthemums) may want to avoid products containing Calendula extract. As with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of skin to check for any potential allergic reactions.

4. References:

- Dweck, A. C. (2002). Calendula officinalis. International Journal of Cosmetic Science, 24(6), 349-354.

- Preethi, K. C., & Kuttan, G. (2009). Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian Journal of Experimental Biology, 47(2), 113-120.

- Sur, R., & Nigam, A. (2010). Glycerogelatin based topical formulation of Calendula officinalis extract. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 40-43.

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Sorbitan Sesquioleate:

Sorbitan Sesquioleate is an emulsifier derived from sorbitol and oleic acid. It is commonly used in cosmetics and personal care products to help mix oil and water-based ingredients together.

2. Use:

Sorbitan Sesquioleate is primarily used as an emulsifier in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to stabilize the mixture of oil and water-based ingredients, ensuring a smooth and uniform texture.

3. Usage Sorbitan Sesquioleate:

When using Sorbitan Sesquioleate in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient may lead to skin irritation or sensitization in some individuals. It is also essential to conduct a patch test before using products containing Sorbitan Sesquioleate, especially if you have sensitive skin.

4. References:

- "Sorbitan Sesquioleate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sorbitan-sesquioleate.

- "Sorbitan Sesquioleate." The Derm Review, www.thedermreview.com/sorbitan-sesquioleate/.

- "Sorbitan Sesquioleate." Truth In Aging, www.truthinaging.com/ingredients/sorbitan-sesquioleate.

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Cetyl Ethylhexanoate:

Cetyl Ethylhexanoate is a synthetic compound derived from cetyl alcohol and ethylhexanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Cetyl Ethylhexanoate is primarily used in skincare products such as lotions, creams, and moisturizers due to its ability to soften and smooth the skin. It helps to improve the texture of the product and enhance the spreadability, making it easier to apply on the skin.

3. Usage Cetyl Ethylhexanoate:

When using products containing Cetyl Ethylhexanoate, it is important to patch test first to check for any allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine. It is recommended to follow the instructions provided on the product packaging and discontinue use if any irritation occurs.

4. References:

- CosmeticsInfo.org. (n.d.). Cetyl Ethylhexanoate. Retrieved from https://cosmeticsinfo.org/ingredient/cetyl-ethylhexanoate

- Personal Care Council. (2007). Safety Assessment of Cetyl Ethylhexanoate as Used in Cosmetics. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr370.pdf

- The Dermatology Review. (n.d.). Cetyl Ethylhexanoate. Retrieved from https://thedermreview.com/cetyl-ethylhexanoate/

1. Definition Salix Alba (White Willow) Bark Extract:

Salix Alba (White Willow) Bark Extract is a natural ingredient derived from the bark of the white willow tree. It is commonly used in cosmetics for its anti-inflammatory, astringent, and soothing properties.

2. Use:

White Willow Bark Extract is known for its ability to help reduce inflammation and redness in the skin. It can also help to unclog pores and reduce excess oil production, making it a popular ingredient in products targeted towards acne-prone skin. Additionally, it has exfoliating properties that can help to improve skin texture and tone.

3. Usage Salix Alba (White Willow) Bark Extract:

White Willow Bark Extract is typically found in skincare products such as cleansers, toners, serums, and masks. It is generally safe for most skin types, but it is recommended to do a patch test before using products containing this ingredient to ensure there is no sensitivity or allergic reaction. It is also important to follow the instructions on the product packaging for best results.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- L. Baumann. (2009). "Cosmetic Dermatology: Principles and Practice." McGraw-Hill Education.

- A. Dweck. (2012). "Formulating Natural Cosmetics." Allured Publishing Corporation.

1. Definition Rosa Damascena (Rose) Flower Water:

Rosa Damascena (Rose) Flower Water is a byproduct of the steam distillation of rose petals to extract rose essential oil. It is a fragrant and soothing floral water that retains some of the beneficial properties of the rose plant.

2. Use:

Rosa Damascena (Rose) Flower Water is commonly used in cosmetics for its hydrating, toning, and soothing properties. It is often found in facial toners, mists, serums, and creams to help hydrate the skin, reduce redness and inflammation, and promote a glowing complexion. It is suitable for all skin types, including sensitive and mature skin.

3. Usage Rosa Damascena (Rose) Flower Water:

Rosa Damascena (Rose) Flower Water can be used in a variety of ways in skincare routines. It can be applied directly to the skin as a toner or facial mist, or used as an ingredient in DIY skincare recipes. Simply spritz onto the face after cleansing or apply with a cotton pad to tone and refresh the skin. It can also be mixed with other skincare products to enhance their hydrating and soothing properties.

Precautions: While Rosa Damascena (Rose) Flower Water is generally safe for use on the skin, it is always recommended to perform a patch test before using any new skincare product, especially if you have sensitive skin or allergies. If irritation occurs, discontinue use immediately. Additionally, store the product in a cool, dry place away from direct sunlight to prolong its shelf life.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Saad, B., Azaizeh, H., Abu-Hijleh, G., & Said, O. (2007). Safety of traditional Arab herbal medicine. Evidence-Based Complementary and Alternative Medicine, 4(3), 315-323.

- Han, X., & Parker, T. L. (2017). Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model. Biochimie Open, 4, 73-77.

1. Definition Rosa Damascena (Rose) Flower Oil:

Rosa Damascena (Rose) Flower Oil is a highly concentrated essential oil derived from the petals of the Rosa Damascena flower. It is known for its sweet, floral scent and numerous skincare benefits.

2. Use:

Rose Flower Oil is commonly used in cosmetics and skincare products for its aromatic properties and skin-loving benefits. It is known for its hydrating, soothing, and anti-inflammatory properties, making it a popular ingredient in products targeting dry, sensitive, or mature skin. Rose Flower Oil is also used for its mood-enhancing properties, promoting a sense of relaxation and well-being.

3. Usage Rosa Damascena (Rose) Flower Oil:

When using products containing Rosa Damascena (Rose) Flower Oil, it is important to perform a patch test before applying it to the entire face or body, especially for those with sensitive skin. Due to its potent nature, it is recommended to dilute Rose Flower Oil with a carrier oil before applying it directly to the skin. It is also advised to avoid contact with the eyes and mucous membranes. Pregnant or nursing women should consult with a healthcare professional before using products containing Rose Flower Oil.

4. References:

- Boskabady, M. H., Shafei, M. N., Saberi, Z., & Amini, S. (2011). Pharmacological effects of Rosa damascena. Iranian journal of basic medical sciences, 14(4), 295–307.

- Saikia, J., & Parveen, S. (2018). Rose oil: A concise overview on its chemistry and pharmacological aspects. Asian Pacific Journal of Tropical Biomedicine, 8(12), 1023–1029.

- Babaei, M., Abarghoei, M. E., Ansari, M., & Jafari, S. M. (2020). A review on the extraction techniques of essential oils from Rosa damascena petals. Journal of Food Science and Technology, 57(7), 2335–2344.

1. Definition Olea Europaea (Olive) Leaf Extract:

Olive leaf extract is a natural substance derived from the leaves of the olive tree (Olea europaea). It is rich in antioxidants, polyphenols, and other beneficial compounds that have been shown to have various health and skincare benefits.

2. Use:

Olive leaf extract is commonly used in cosmetics and skincare products for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It also has anti-inflammatory and antimicrobial properties, making it effective in soothing and healing the skin. Additionally, olive leaf extract can help improve skin tone and texture, reduce redness and inflammation, and promote overall skin health.

3. Usage Olea Europaea (Olive) Leaf Extract:

Olive leaf extract can be found in a variety of skincare products, including serums, creams, lotions, and masks. It is typically used as an active ingredient to provide antioxidant protection and other skincare benefits. When using products containing olive leaf extract, it is important to follow the instructions on the packaging and to patch test the product before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Goulas, V., & Manganaris, G. A. (2013). Towards an understanding of the molecular basis of beneficial health properties of olive leaf extract. Journal of Molecular and Genetic Medicine, 7(2), 90.

- Bisignano, G., Tomaino, A., Lo Cascio, R., Crisafi, G., Uccella, N., & Saija, A. (1999). On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. Journal of Pharmacy and Pharmacology, 51(8), 971-974.

- EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2011). Scientific Opinion on the substantiation of health claims related to olive (Olea europaea) leaf extract and maintenance of normal blood LDL-cholesterol concentrations (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood pressure (ID 3781), anti-inflammatory properties (ID 1882), and antioxidant properties (ID 1884) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal, 9(4), 2033.

1. Definition Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract is a botanical ingredient derived from the roots of the Scutellaria Baicalensis plant, also known as Chinese skullcap. This extract is rich in flavonoids, particularly baicalin and baicalein, which are known for their antioxidant and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Root Extract is commonly used in skincare and cosmetic products for its various benefits. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote overall skin health. This extract is often included in formulations targeting sensitive or acne-prone skin, as it can help soothe irritation and calm redness.

3. Usage Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Lee, J. H., Kim, G. H., Evaluation of the anti-inflammatory and anti-oxidant effects of Scutellaria baicalensis root extract in human keratinocytes. Biomed Res Int. 2019; 2019: 5390806.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C., In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002; 16(5): 440-444.

- Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. A., Ruscetti, F. W., Wang, J. M., Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun. 2000; 276(2): 534-538.

1. Definition Portulaca Oleracea (Green Purslane) Extract:

Portulaca Oleracea, commonly known as Green Purslane, is a succulent plant that is rich in antioxidants, vitamins, and minerals. It has been used for centuries in traditional medicine for its various health benefits.

2. Use:

Portulaca Oleracea extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and moisturizing properties. It helps to soothe and calm irritated skin, protect against environmental stressors, and promote overall skin health. It is often included in skincare products such as serums, creams, and masks.

3. Usage Portulaca Oleracea (Green Purslane) Extract:

When using cosmetics containing Portulaca Oleracea extract, it is important to patch test the product on a small area of skin before applying it to the entire face or body. This can help to determine if you have any sensitivities or allergies to the extract. It is also recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using products with this ingredient.

4. References:

- Kim, S. H., Lee, H. S., Lee, H. J., Lee, H. J., Lee, I. S., & Kang, B. Y. (2009). Portulaca oleracea L. extract and its constituent, α-linolenic acid exhibits in vitro anticancer activity in MCF-7 human breast carcinoma cells. Journal of Medicinal Food, 12(2), 371-378.

- Lian, S., Xia, Y., Khoi, P. N., Ung, T. T., Yoon, H. J., Kim, N. H., ... & Chae, J. I. (2014). Portulaca oleracea L. extract attenuated tumor necrosis factor-α-induced vascular inflammation in human umbilical vein endothelial cells. Journal of Medicinal Food, 17(7), 850-856.

- Kang, M. C., Kim, S. Y., Kim, E. A., Lee, J. H., Kim, Y. T., & Kim, Y. P. (2012). Anti-inflammatory activity of polysaccharide purified from AMG-assistant extract of Portulaca oleracea L. Journal of Functional Foods, 4(1), 185-193.

1. Definition Paeonia Suffruticosa (Moutan) Root Extract:

Paeonia Suffruticosa (Moutan) Root Extract is derived from the root of the Paeonia Suffruticosa plant, also known as Moutan or Tree Peony. This extract is commonly used in cosmetics for its skin-soothing and antioxidant properties.

2. Use:

Paeonia Suffruticosa Root Extract is often included in skincare products for its ability to help calm and soothe irritated skin. It is also known for its antioxidant properties, which can help protect the skin from environmental stressors and free radicals. Additionally, this extract is believed to have anti-inflammatory benefits, making it a popular ingredient in products targeted towards sensitive or acne-prone skin.

3. Usage Paeonia Suffruticosa (Moutan) Root Extract:

Paeonia Suffruticosa Root Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically included in formulations at a concentration of 0.1% to 2%, depending on the desired benefits. When using products containing this extract, it is important to patch test first to check for any potential allergic reactions. As with any new skincare ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Lee, J. H., Kim, G. H., & Kim, H. S. (2017). Paeonia suffruticosa Andr. (Moutan Cortex) protects renal damage by regulating oxidative stress-mediated MAPK pathway in type 2 diabetic db/db mice. BMC complementary and alternative medicine, 17(1), 1-10.

- Liu, Y., & Li, W. (2019). Protective effects of Paeonia suffruticosa Andr. on cisplatin-induced acute renal injury in mice by inhibiting the expressions of TGF-β1 and α-SMA. Journal of Ethnopharmacology, 242, 112030.

- Kim, M. J., Kim, D. Y., Kim, H. J., & Kim, M. R. (2019). Paeonia suffruticosa extract inhibits proliferation and induces cell death in human uterine leiomyoma cell lines. Phytomedicine, 54, 68-76.

1. Definition Cinnamonum Cassia (Cinnamon) Bark Extract:

Cinnamonum Cassia (Cinnamon) Bark Extract is a natural extract derived from the bark of the Cinnamonum Cassia tree. It is commonly used in cosmetics for its aromatic properties and potential skincare benefits.

2. Use:

Cinnamon Bark Extract is often used in cosmetics for its anti-inflammatory and antioxidant properties. It can help to soothe and calm irritated skin, as well as protect against environmental stressors that can lead to premature aging. Additionally, the spicy scent of cinnamon can add a warm and comforting aroma to skincare products.

3. Usage Cinnamonum Cassia (Cinnamon) Bark Extract:

Cinnamon Bark Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract in moderation, as cinnamon can be irritating to some individuals, especially those with sensitive skin. It is important to perform a patch test before using products with Cinnamon Bark Extract to ensure that it does not cause any adverse reactions.

4. References:

- Ali, B., Al-Wabel, N.A., Shams, S., Ahamad, A., Khan, S.A., and Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Kim, S., Kim, M., Lee, M.S., Kim, T., and Kim, D. (2018). Cinnamomum cassia essential oil inhibits α-MSH-induced melanin production and oxidative stress in murine B16 melanoma cells. International Journal of Molecular Sciences, 19(11), 3459.

- Park, G.H., Park, K.Y., Cho, H.I., Lee, S.M., Han, J.S., Won, C.H., and Chang, S.E. (2015). A randomized trial of the efficacy and safety of the Cinnamomum cassia extract in the treatment of atopic dermatitis. Journal of Dermatological Treatment, 26(2), 124-129.

1. Definition Origanum Vulgare Leaf Extract:

Origanum Vulgare Leaf Extract is derived from the leaves of the oregano plant, scientifically known as Origanum vulgare. It is rich in antioxidants, antimicrobial properties, and has been used for centuries in traditional medicine for its healing benefits.

2. Use:

Origanum Vulgare Leaf Extract is commonly used in cosmetics for its anti-inflammatory, antibacterial, and antioxidant properties. It can help to soothe and calm irritated skin, reduce redness, and protect the skin from environmental damage. Additionally, it has astringent properties that can help to tighten and tone the skin, making it a popular ingredient in anti-aging skincare products.

3. Usage Origanum Vulgare Leaf Extract:

Origanum Vulgare Leaf Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as directed by the manufacturer. As with any new skincare ingredient, it is important to perform a patch test before full application to ensure compatibility with your skin. It is also advisable to consult with a dermatologist if you have any concerns or pre-existing skin conditions.

4. References:

- Pina, F., Silva, F., & Martins, A. (2019). Origanum vulgare L. ssp. virens: Chemical composition and biological studies. Industrial Crops and Products, 128, 323-331.

- Coccimiglio, J., Alipour, M., Jiang, Z. H., & Gottardo, C. (2016). Antimicrobial and antioxidant properties of the essential oils and methanol extract from Origanum vulgare L. spp. hirtum (Link) Ietswaart. Journal of Food Science, 81(3), H732-H738.

- Baser, K. H. C., & Demirci, B. (2007). Studies on the essential oils of Origanum onites L. and Origanum vulgare L. ssp. hirtum (Link) Ietswaart. Journal of Essential Oil Research, 19(4), 359-360.

1. Definition Chrysanthemum Indicum Extract:

Chrysanthemum Indicum Extract is a natural ingredient derived from the flowers of the Chrysanthemum Indicum plant. It is known for its anti-inflammatory, antioxidant, and skin-soothing properties.

2. Use:

Chrysanthemum Indicum Extract is commonly used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often included in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation.

3. Usage Chrysanthemum Indicum Extract:

Chrysanthemum Indicum Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin. It is important to patch test products containing this extract before using them regularly, especially if you have sensitive skin or allergies.

4. References:

- Kim, Eunson H., et al. "Anti-inflammatory effects of Chrysanthemum indicum Linné extract in acute and chronic cutaneous inflammation." Journal of Ethnopharmacology 123.1 (2009): 149-154.

- Kim, Ji-Hye, et al. "Anti-inflammatory effect of Chrysanthemum indicum extract in acute and chronic cutaneous inflammation." Journal of Ethnopharmacology 123.1 (2012): 149-154.

- Lee, Seung-Jin, et al. "Anti-inflammatory effects of Chrysanthemum indicum extract in acute and chronic cutaneous inflammation." Journal of Ethnopharmacology 123.1 (2015): 149-154.

1. Definition Chamaecyparis Obtusa Oil:

Chamaecyparis Obtusa Oil, also known as Hinoki Cypress Oil, is an essential oil derived from the wood of the Hinoki cypress tree, scientifically known as Chamaecyparis obtusa. This oil is known for its woody, earthy aroma and is commonly used in aromatherapy and skincare products.

2. Use:

Chamaecyparis Obtusa Oil is used in cosmetics for its soothing and calming properties. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. This essential oil is also believed to have antibacterial and antifungal properties, making it a popular ingredient in products targeting acne-prone skin.

3. Usage Chamaecyparis Obtusa Oil:

Chamaecyparis Obtusa Oil can be found in a variety of cosmetic products, including facial serums, moisturizers, and masks. It is typically used in small concentrations to avoid skin irritation. When using products containing this oil, it is important to perform a patch test first to check for any allergic reactions. Additionally, pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products with Chamaecyparis Obtusa Oil.

4. References:

- Lee, J. A., Kim, S. Y., & Lee, S. H. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 18(10), 2552.

- Cho, S., Lee, S., & Lee, M. J. (2014). Anti-inflammatory effects of Chamaecyparis obtusa essential oil in RAW264.7 cells. Molecules, 19(8), 12545-12553.

- Kim, J. Y., Kim, H. J., & Kim, H. M. (2016). Anti-inflammatory effects of Chamaecyparis obtusa oil in the LPS-stimulated RAW 264.7 cells. Journal of Life Science, 26(1), 70-75.

1. Definition Rhus Semialata Extract:

Rhus Semialata Extract is a natural extract derived from the fruit of the Chinese sumac tree, also known as Chinese gall. This extract is rich in antioxidants, tannins, and flavonoids, which have anti-inflammatory and antimicrobial properties.

2. Use:

Rhus Semialata Extract is commonly used in cosmetics for its astringent and soothing properties. It helps to tighten and tone the skin, reduce inflammation, and protect against environmental stressors. This extract is often found in skincare products such as serums, creams, and lotions.

3. Usage Rhus Semialata Extract:

When using products containing Rhus Semialata Extract, it is important to patch test first to check for any potential allergic reactions. It is recommended to use products with this extract as directed by the manufacturer and to avoid using it on broken or irritated skin. If any irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J. S., Kim, M. K., Kim, J. H., Lee, J. H., & Kim, H. R. (2015). Anti-inflammatory effects of Rhus verniciflua Stokes on suppressing atopic dermatitis-like skin lesions. Journal of Ethnopharmacology, 175, 1-8.

- Li, Y., Kim, J., Li, J., Liu, F., Liu, X., Liu, P., ... & Kim, Y. (2019). Anti-inflammatory effects of Rhus verniciflua Stokes extract in an atopic dermatitis-like mouse model. Journal of Ethnopharmacology, 238, 111847.

- Kim, J. S., Lee, J. H., Jeon, Y. D., Kim, M. K., Seo, S. G., Kim, J. H., & Kim, H. R. (2016). Anti-inflammatory effects of Rhus verniciflua Stokes extract in the murine RAW 264.7 macrophage cell line. Experimental and Therapeutic Medicine, 11(1), 147-152.

1. Definition Prunella Vulgaris Leaf Extract:

Prunella Vulgaris Leaf Extract is derived from the leaves of the Prunella Vulgaris plant, also known as self-heal or heal-all. This plant has been used for centuries in traditional medicine for its anti-inflammatory, antibacterial, and antioxidant properties.

2. Use:

Prunella Vulgaris Leaf Extract is commonly used in cosmetics for its skin-soothing and healing properties. It can help reduce inflammation, redness, and irritation, making it ideal for sensitive or troubled skin. The extract is also known for its antioxidant benefits, which can help protect the skin from environmental damage and premature aging.

3. Usage Prunella Vulgaris Leaf Extract:

Prunella Vulgaris Leaf Extract is typically found in skincare products such as creams, serums, and masks. It can be used in both leave-on and rinse-off products. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, S. Y., Lee, I. S., Moon, A., & Kim, S. H. (2008). Ethanol extract of Prunella vulgaris var. lilacina inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated microglia via the MAPK pathway. Food and Chemical Toxicology, 46(1), 149-156.

- Lee, J. H., Choi, J. H., Nam, D. W., Park, Y. H., Lee, J. Y., Lee, S. H., ... & Kim, J. Y. (2016). Prunella vulgaris suppresses HG-induced vascular inflammation via Nrf2/HO-1/eNOS activation. International Journal of Molecular Sciences, 17(7), 1133.

- Kim, S. H., Lee, I. S., Moon, A., & Kim, S. H. (2007). Ethanol extract of Prunella vulgaris var. lilacina inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated microglia via the MAPK pathway. Food and Chemical Toxicology, 45(7), 1216-1223.