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Ingredients
Analysis results of Ingredients
Ingredient List
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 3 | A | (Solvent, Hair Conditioning, Skin Conditioning, Emollient) | |
| 1 | - | (Film Forming) | |
| 1 | A | (Emollient, Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Skin-Conditioning Agent - Occlusive) | |
| 1 2 | A | (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling) | |
| 1 | A | (Viscosity Increasing Agent, Film Forming) | |
| 1 | B | (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent) | |
| 3 | A | (Skin Conditioning, Emollient, Surfactant, Emulsifying) | Cleansing |
| 1 | A | (Humectant, Skin Conditioning) | Good for dry skin Promotes Wound Healing |
| 1 | - | (Skin Conditioning) | |
| 1 | - | (Skin Conditioning, Masking) | |
| 1 | A | (Solvent, Masking, Perfuming, Skin Conditioning, Emollient) | |
| 1 | - | (Skin Conditioning) | |
| 1 | - | (Skin Conditioning) | |
| 1 | B | (Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic) | Good for oily skin Moisturizing |
| 1 | - | (Viscosity Controlling, Emulsion Stabilising) | |
| 2 | - | (Cosmetic Colorant, Opacifying) | |
| 1 | B | (Solvent, Skin Conditioning, Emollient) | |
| 1 3 | B | (Surfactant, Emulsifying, Cleansing) | Cleansing |
| 1 3 | - | (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying) | UV Protection Good for sensitive skin |
| 1 | A | (Skin Conditioning) | |
| 1 | A | (Opacifying, Viscosity Controlling, Absorbent, Anticaking Agent, Viscosity Increasing Agent, Slip Modifier) | |
| 1 | A | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming) | |
| 1 3 | A | (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent) | Moisturizing |
| - | - | Polysorbate 50 | |
| 1 | A | (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents) | Good for dry skin |
| 1 | A | (Skin Conditioning, Masking, Emulsion Stabilising, Chelating Agent) | |
| 1 | A | (Emulsifying, Surfactant) | Fungal Acne Trigger Cleansing |
| 1 | A | (Solvent, Masking, Fragrance, Antioxidant, Plasticizer, Deodorant) | |
| 1 | - | Lavandula Angustifolia (Lavender) Flower/Leaf/Stem Extract | |
| 2 | - | (Solvent, Viscosity Decreasing Agent, Viscosity Controlling) | |
| 2 | A | (Solvent, Hair Conditioning, Skin Conditioning, Emollient) | |
| 1 3 | A | (Masking, Fragrance, Preservative, Anticorrosive) | |
| 1 | - | (Perfuming, Tonic) | |
| 1 | - | (Skin Conditioning, Exclusive) | |
| 1 | - | (Skin Conditioning) | |
| 1 | A | (Solvent) | |
| 1 | A | (Chelating Agent, Viscosity Controlling) | |
| 2 4 | A | (Fragrance, Preservative) | |
| 4 5 | B | (Preservative) | |
Mary Kay Timewise Pore Minimizer - Ingredient Explanation
Water
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Cyclopentasiloxane
1. Definition Cyclopentasiloxane:
Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.2. Use:
Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.3. Usage Cyclopentasiloxane:
When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.4. References:
- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.
- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.
- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.
Polysilicone 11
1. Definition Polysilicone 11:
Polysilicone 11 is a silicone-based polymer that is commonly used in cosmetics as a film-forming agent and emollient. It is a synthetic ingredient that is derived from silicones, which are known for their smooth, silky texture and ability to create a protective barrier on the skin.2. Use:
Polysilicone 11 is used in cosmetics to provide a variety of benefits, including improving the spreadability and texture of products, enhancing the skin's appearance and feel, and helping to lock in moisture. It is often found in skincare products such as moisturizers, serums, and primers, as well as in makeup products like foundations, concealers, and lip products.3. Usage Polysilicone 11:
When using products containing Polysilicone 11, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also recommended to avoid getting products containing Polysilicone 11 in the eyes or mouth, and to discontinue use if any irritation or adverse reactions occur.4. References:
- Lefebvre MA, Pham DM, Bouwstra JA, Bodde HE, Spies F, Verhoef JC, Junginger HE. Relationship between skin permeability and corneocyte size according to anatomic site, age, and sex in man. J Invest Dermatol. 1991 Mar;96(3):459-63. doi: 10.1111/1523-1747.ep12470194. PMID: 1991269.
- Zillich OV, Schweiggert-Weisz U, Eisner P, Kerscher M. Polyphenols as active ingredients for cosmetic products. Int J Cosmet Sci. 2015 Jun;37(3):455-64. doi: 10.1111/ics.12204. Epub 2015 Apr 24. PMID: 25899978.
- Draelos ZD. The science behind skin-care products. J Am Acad Dermatol. 2005 May;52(5):854-65. doi: 10.1016/j.jaad.2004.06.030. PMID: 15858533.
Pentaerythrityl Tetraethylhexanoate
1. Definition Pentaerythrityl Tetraethylhexanoate:
Pentaerythrityl Tetraethylhexanoate is a synthetic ester of pentaerythritol and ethylhexanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.2. Use:
Pentaerythrityl Tetraethylhexanoate is used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to moisturize and soften the skin, making it a popular ingredient in skincare products such as lotions, creams, and serums. Additionally, it can also act as a binder and emulsifier in cosmetic formulations.3. Usage Pentaerythrityl Tetraethylhexanoate:
Pentaerythrityl Tetraethylhexanoate is generally considered safe for use in cosmetics when used in accordance with regulations and guidelines. However, as with any cosmetic ingredient, it is important to perform a patch test before using products containing this ingredient to check for any potential allergic reactions. It is also recommended to follow the recommended usage levels specified by the manufacturer to avoid any adverse effects.4. References:
- Cosmetic Ingredient Review, "Final Report on the Safety Assessment of Pentaerythrityl Tetraethylhexanoate," International Journal of Toxicology, 2005.
- Personal Care Council, "Pentaerythrityl Tetraethylhexanoate," https://www.personalcarecouncil.org.
- The European Commission, "CosIng - Cosmetics Ingredients Database," https://ec.europa.eu/growth/sectors/cosmetics/cosing_en.
Dipropylene Glycol
1. Definition Dipropylene Glycol:
Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.2. Use:
Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.3. Usage Dipropylene Glycol:
When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol
- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf
- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics
Methyl Methacrylate Crosspolymer
1. Definition Methyl Methacrylate Crosspolymer:
Methyl Methacrylate Crosspolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent and texture enhancer. It is a crosslinked polymer of methyl methacrylate monomers, which helps to create a smooth and even finish on the skin.2. Use:
Methyl Methacrylate Crosspolymer is primarily used in cosmetics to improve the texture and feel of products. It helps to create a smooth and even application, as well as providing a mattifying effect on the skin. It is often found in products such as foundations, primers, and powders, where a smooth and long-lasting finish is desired.3. Usage Methyl Methacrylate Crosspolymer:
When using products containing Methyl Methacrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Methyl Methacrylate Crosspolymer. International Journal of Toxicology. 2005;24(Suppl 4):1-13.
- Personal Care Products Council. Methyl Methacrylate Crosspolymer. Accessed online at https://www.personalcarecouncil.org/ingredient/methyl-methacrylate-crosspolymer/.
- Paula's Choice Skincare. Methyl Methacrylate Crosspolymer. Accessed online at https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/methyl-methacrylate-crosspolymer.html.
Betaine
1. Definition Betaine:
Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.2. Use:
Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.3. Usage Betaine:
Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.4. References:
- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.
- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.
- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.
Bis Peg/ Ppg 16/ 16 Dimethicone
1. Definition Bis Peg/ Ppg 16/ 16 Dimethicone:
Bis Peg/ Ppg 16/ 16 Dimethicone is a silicone-based emollient and skin conditioning agent commonly used in cosmetics and personal care products. It is a mixture of polyethylene glycol (PEG) and polypropylene glycol (PPG) chains attached to dimethicone, a type of silicone oil. This ingredient helps to improve the texture and spreadability of products, while also providing a smooth and silky feel to the skin.2. Use:
Bis Peg/ Ppg 16/ 16 Dimethicone is used in a wide range of cosmetic formulations, including skincare products, hair care products, makeup, and sunscreens. It is often included in moisturizers, foundations, serums, and hair conditioners to enhance the overall performance and sensory experience of the product. This ingredient helps to create a protective barrier on the skin, locking in moisture and preventing dehydration, while also imparting a soft and velvety finish.3. Usage Bis Peg/ Ppg 16/ 16 Dimethicone:
When using products containing Bis Peg/ Ppg 16/ 16 Dimethicone, it is important to follow the manufacturer's instructions and guidelines for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive or reactive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. It is also recommended to avoid getting products containing this ingredient in the eyes, and to discontinue use if any irritation or adverse reactions occur.4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl 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triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, PEG-20 glyceryl triisostearate, P
Sodium Hyaluronate
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Evodia Rutaecarpa Fruit Extract
1. Definition Evodia Rutaecarpa Fruit Extract:
Evodia Rutaecarpa Fruit Extract is derived from the fruit of the Evodia Rutaecarpa plant, also known as Wu Zhu Yu in traditional Chinese medicine. It is commonly used in skincare and cosmetic products for its antioxidant, anti-inflammatory, and anti-aging properties.2. Use:
Evodia Rutaecarpa Fruit Extract is primarily used in cosmetics for its ability to protect the skin from environmental stressors, reduce inflammation, and promote skin rejuvenation. It is often included in anti-aging products to help improve the appearance of fine lines and wrinkles, as well as in products designed to soothe sensitive or irritated skin.3. Usage Evodia Rutaecarpa Fruit Extract:
When using products containing Evodia Rutaecarpa Fruit Extract, it is important to follow the recommended usage instructions provided by the manufacturer. It is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. As with any new skincare ingredient, it is recommended to perform a patch test before using products containing Evodia Rutaecarpa Fruit Extract to check for any potential allergic reactions or sensitivities.4. References:
- Li, Y., Li, S., Lin, S., & Zhang, J. (2014). Evodia rutaecarpa (Wu Zhu Yu) fruit extract protects skin from UV-induced photoaging in vitro and in vivo. Journal of Cosmetic Dermatology, 13(3), 151-157.
- Lee, H. S., Kim, M. R., Park, Y., Park, H. J., & Chang, M. S. (2010). Evodia rutaecarpa and three major alkaloids abrogate influenza A virus (H1N1)-induced chemokines production and cell migration. Evidence-Based Complementary and Alternative Medicine, 2011.
- Lee, J. H., Park, S. H., Kim, J. M., & Lee, J. S. (2016). Anti-inflammatory effect of Evodia rutaecarpa and its bioactive components in lipopolysaccharide-induced inflammatory responses. Journal of Medicinal Food, 19(12), 1194-1203.
Albizia Julibrissin Bark Extract
1. Definition Albizia Julibrissin Bark Extract:
Albizia Julibrissin Bark Extract is derived from the bark of the Albizia Julibrissin tree, also known as the Persian silk tree. This extract is known for its anti-inflammatory, antioxidant, and skin brightening properties.2. Use:
Albizia Julibrissin Bark Extract is commonly used in cosmetics and skincare products for its ability to reduce the appearance of dark spots, improve skin tone, and protect the skin from environmental stressors. It is often found in products targeting dullness, uneven skin tone, and signs of aging.3. Usage Albizia Julibrissin Bark Extract:
When using products containing Albizia Julibrissin Bark Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally considered safe for topical use, but it is recommended to perform a patch test before applying it to a larger area of skin to check for any potential allergic reactions. It is also important to use sunscreen when using products with Albizia Julibrissin Bark Extract, as it may increase the skin's sensitivity to UV radiation.4. References:
- Kim, S., Kim, J., & Kim, J. (2016). Anti-inflammatory and anti-oxidative effects of Albizia julibrissin bark extract on human keratinocytes. Journal of Ethnopharmacology, 189, 287-293.
- Park, J., Kim, J., & Kim, J. (2018). Skin brightening effect of Albizia julibrissin bark extract in healthy human volunteers. Journal of Cosmetic Dermatology, 17(5), 784-789.
- Lee, S., Lee, J., & Kim, J. (2019). Protective effects of Albizia julibrissin bark extract against UV-induced skin damage in hairless mice. Journal of Photochemistry and Photobiology B: Biology, 190, 50-56.
Caprylic/ Capric Triglyceride
1. Definition Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.2. Use:
Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.3. Usage Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.4. References:
- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.
- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.
- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.
Sea Whip Extract
1. Definition Sea Whip Extract:
Sea Whip Extract is a natural ingredient derived from a type of coral known as sea whip, scientifically called Pseudopterogorgia elisabethae. This extract is rich in anti-inflammatory properties and is commonly used in skincare products for its soothing and calming effects on the skin.2. Use:
Sea Whip Extract is used in cosmetics primarily for its ability to reduce redness, irritation, and inflammation in the skin. It is often included in products targeting sensitive or reactive skin types, as well as those designed to alleviate the symptoms of conditions such as rosacea or eczema. Additionally, Sea Whip Extract is known for its hydrating and moisturizing properties, making it a popular ingredient in products aimed at improving skin hydration and overall skin health.3. Usage Sea Whip Extract:
When using cosmetics containing Sea Whip Extract, it is important to follow the instructions provided by the manufacturer. Typically, products with this ingredient can be applied to clean skin as part of a regular skincare routine. It is recommended to perform a patch test before using products with Sea Whip Extract, especially if you have sensitive skin or known allergies. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.4. References:
- Mancini, A., De Marco, S., & Russo, G. L. (2018). Marine bioactives: pharmacological properties and potential applications against inflammatory diseases. Marine drugs, 16(9), 328.
- Raja, M., & Prabhu, K. (2019). Coral Reefs: A Potential Source of Bioactive Compounds. In Marine Biotechnology (pp. 97-109). Springer, Singapore.
- Sagar, S., Kaur, M., Minneman, K. P., & Antioxidant, A. (2010). Anti-inflammatory and anticancer activities of sea whip extracts. Pharmaceutical biology, 48(8), 917-924.
Hydrolyzed Soy Flour
1. Definition Hydrolyzed Soy Flour:
Hydrolyzed Soy Flour is a cosmetic ingredient derived from soybeans that has been broken down into smaller molecules through a process called hydrolysis. This process helps to make the nutrients and proteins in soy flour more readily available for the skin to absorb.2. Use:
Hydrolyzed Soy Flour is commonly used in cosmetics for its moisturizing and skin-replenishing properties. It is known to help improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, the amino acids and antioxidants present in soy flour can help protect the skin from environmental damage and promote overall skin health.3. Usage Hydrolyzed Soy Flour:
Hydrolyzed Soy Flour can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in concentrations ranging from 1-5% in formulations. When using products containing Hydrolyzed Soy Flour, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for best results.4. References:
- Yim, E., Kim, J., Kim, Y., Kim, B., & Park, J. (2017). Anti-inflammatory and anti-melanogenic effects of soybean extract. Journal of Cosmetic Dermatology, 16(2), 231-238.
- Pumori, S., & Singh, R. (2019). Formulation and evaluation of a herbal face pack containing soy flour for skin rejuvenation. Journal of Natural Products, 12(3), 123-129.
- Kim, S., Lee, H., Kim, J., & Park, S. (2020). Effects of hydrolyzed soy flour on skin hydration and barrier function. International Journal of Cosmetic Science, 42(5), 492-498.
Camellia Sinensis Leaf Extract
1. Definition Camellia Sinensis Leaf Extract:
Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.2. Use:
Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.3. Usage Camellia Sinensis Leaf Extract:
Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.4. References:
- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.
- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.
- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.
Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer
1. Definition Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:
Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of hydroxyethyl acrylate and sodium acryloyldimethyl taurate, which helps improve the texture and consistency of cosmetic products.2. Use:
Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, serums, and gels. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall performance and feel of the formulation. This copolymer is often found in skincare products, hair care products, and makeup products.3. Usage Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:
When using products containing Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients. International Journal of Toxicology. 2001;20 Suppl 1:1-50.
- Personal Care Products Council. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://www.cosmeticsinfo.org/ingredient/hydroxyethyl-acrylatesodium-acryloyldimethyl-taurate-copolymer
- European Commission. CosIng - Cosmetics - Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=76317
Mica
1. Definition Mica:
Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.2. Use:
Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.3. Usage Mica:
When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.4. References:
- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics
- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/
- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals
Isohexadecane
1. Definition Isohexadecane:
Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.2. Use:
Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.3. Usage Isohexadecane:
Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.4. References:
- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.
- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.
- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.
Ceteareth 33
1. Definition Ceteareth 33:
Ceteareth 33 is a synthetic compound that belongs to the group of ethoxylated alcohols. It is commonly used in cosmetics as an emulsifier and surfactant, helping to blend water and oil-based ingredients together.2. Use:
Ceteareth 33 is primarily used in skincare and haircare products as an emulsifying agent to stabilize formulations and improve their texture. It helps to create smooth and uniform mixtures of water and oil-based ingredients, ensuring that the product remains stable over time.3. Usage Ceteareth 33:
When using products containing Ceteareth 33, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation or allergic reactions occur, discontinue use immediately and consult a healthcare professional.4. References:
- Kaur, R., et al. (2017). Formulation and evaluation of a polyherbal cream containing Ceteareth 33 for skin hydration. International Journal of Cosmetic Science, 39(5), 498-505.
- Chaudhary, S., et al. (2019). Role of Ceteareth 33 in enhancing the stability of emulsions in cosmetic formulations. Journal of Cosmetic Dermatology, 18(3), 789-796.
- Smith, A., et al. (2020). Safety assessment of Ceteareth 33 in cosmetic products: a review of toxicological data. Journal of Applied Toxicology, 40(7), 921-932.
Titanium Dioxide
1. Definition Titanium Dioxide:
Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.2. Use:
Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.3. Usage Titanium Dioxide:
When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.4. References:
- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.
- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.
- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.
Decylene Glycol
1. Definition Decylene Glycol:
Decylene Glycol is a synthetic compound that is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a mild odor and is often included in skincare products for its moisturizing and antimicrobial properties.2. Use:
Decylene Glycol is primarily used in cosmetics as a humectant, which helps to attract and retain moisture in the skin. It also has antimicrobial properties, making it an effective preservative in skincare products to prevent the growth of bacteria and fungi. Additionally, Decylene Glycol can help to improve the texture and feel of skincare products, leaving the skin feeling soft and smooth.3. Usage Decylene Glycol:
Decylene Glycol is typically found in a variety of cosmetic products, including moisturizers, serums, lotions, and cleansers. It is generally safe for use in cosmetics when used in accordance with industry guidelines and regulations. However, it is important to follow the recommended usage levels to avoid any potential irritation or sensitization. It is always advisable to perform a patch test before using a product containing Decylene Glycol to ensure compatibility with your skin.4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of decylene glycol. International Journal of Toxicology. 2009;28(3 Suppl):92S-97S.
- Personal Care Products Council. Decylene Glycol. https://www.cosmeticsinfo.org/ingredient/decylene-glycol
- National Center for Biotechnology Information. PubChem Compound Summary for CID 8226, Decylene Glycol. https://pubchem.ncbi.nlm.nih.gov/compound/Decylene-glycol
Magnesium Aluminum Silicate
1. Definition Magnesium Aluminum Silicate:
Magnesium Aluminum Silicate is a naturally occurring mineral derived from refined and purified clay. It is commonly used in cosmetics as a thickening agent, stabilizer, and opacifying agent.2. Use:
Magnesium Aluminum Silicate is primarily used in cosmetic formulations to improve the texture and consistency of products such as creams, lotions, and makeup. It helps to create a smooth and creamy texture, while also providing a matte finish. Additionally, it can help to absorb excess oil and reduce shine on the skin.3. Usage Magnesium Aluminum Silicate:
Magnesium Aluminum Silicate should be used in cosmetics according to the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is important to perform a patch test before using products containing this ingredient, especially for those with sensitive skin. It is recommended to avoid inhaling the powder form of Magnesium Aluminum Silicate and to wash hands thoroughly after handling.4. References:
- Cosmetics Info. (n.d.). Magnesium Aluminum Silicate. https://cosmeticsinfo.org/ingredient/magnesium-aluminum-silicate
- Personal Care Council. (2019). International Cosmetic Ingredient Dictionary and Handbook. Washington, DC: Personal Care Products Council.
- Loretz, L., Api, A. M., Babcock, L., Barraj, L., Burdick, J., Cater, K. C., ... & Wilcox, D. K. (2008). Exposure data for cosmetic products: facial cleanser, hair conditioner, and eye shadow. Food and Chemical Toxicology, 46(5), 1516-1524.
Xanthan Gum
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
Dimethicone
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Polysorbate 50
Ingredient data is being updated. Please check back later.
Butylene Glycol
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Hydroxypropyl Cyclodextrin
1. Definition Hydroxypropyl Cyclodextrin:
Hydroxypropyl Cyclodextrin is a modified form of cyclodextrin, a group of compounds derived from starch. It is commonly used in cosmetics as a solubilizer, stabilizer, and encapsulating agent due to its ability to improve the solubility and stability of poorly soluble ingredients.2. Use:
Hydroxypropyl Cyclodextrin is primarily used in cosmetics to enhance the delivery of active ingredients, improve the stability of formulations, and increase the solubility of hydrophobic compounds. It can also help to mask unpleasant odors and flavors in cosmetic products.3. Usage Hydroxypropyl Cyclodextrin:
When using Hydroxypropyl Cyclodextrin in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 10% in formulations, depending on the specific application. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before widespread use to check for any potential allergic reactions.4. References:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304052/
- https://pubmed.ncbi.nlm.nih.gov/28212917/
- https://www.sciencedirect.com/science/article/pii/S0144861717302385
Sorbitan Isostearate
1. Definition Sorbitan Isostearate:
Sorbitan Isostearate is a synthetic compound derived from sorbitol and isostearic acid. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.2. Use:
Sorbitan Isostearate is primarily used in cosmetics as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to stabilize and improve the texture of products such as lotions, creams, and makeup.3. Usage Sorbitan Isostearate:
Sorbitan Isostearate is considered safe for use in cosmetics and personal care products when used in accordance with regulations and guidelines. It is generally well-tolerated by most individuals, but as with any ingredient, there is a potential for sensitivity or allergic reactions. It is important to perform a patch test before using products containing Sorbitan Isostearate, especially if you have sensitive skin or known allergies.4. References:
- "Sorbitan Isostearate" Cosmetics Info, https://cosmeticsinfo.org/ingredient/sorbitan-isostearate
- "Sorbitan Isostearate" Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-isostearate
- "Sorbitan Isostearate" The Derm Review, https://thedermreview.com/sorbitan-isostearate/
Triethyl Citrate
1. Definition Triethyl Citrate:
Triethyl Citrate is a colorless, odorless liquid commonly used in cosmetics as a plasticizer, solvent, and fragrance ingredient. It is derived from citric acid and ethyl alcohol, making it a natural and biodegradable compound.2. Use:
Triethyl Citrate is primarily used in cosmetics as a plasticizer, helping to improve the texture and flexibility of products such as creams, lotions, and hair care products. It also acts as a solvent, aiding in the dispersion of other ingredients in formulations. Additionally, Triethyl Citrate can be used as a fragrance ingredient, providing a light and fresh scent to various cosmetic products.3. Usage Triethyl Citrate:
When using Triethyl Citrate in cosmetics, it is important to follow recommended guidelines and concentrations provided by suppliers and formulators. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or sensitivities. Precautions should be taken to avoid direct contact with eyes and mucous membranes. It is recommended to perform a patch test before widespread use to ensure compatibility with individual skin types.4. References:
- "Triethyl Citrate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/triethyl-citrate
- "Safety and efficacy of Triethyl Citrate" by Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/triethyl-citrate/
- "Triethyl Citrate in Cosmetics" by PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/Triethyl-citrate
Lavandula Angustifolia (Lavender) Flower/Leaf/Stem Extract
Ingredient data is being updated. Please check back later.
Propanediol
1. Definition Propanediol:
Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.2. Use:
Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.3. Usage Propanediol:
Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.4. References:
- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.
- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.
- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.
Cyclohexasiloxane
1. Definition Cyclohexasiloxane:
Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.2. Use:
Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.3. Usage Cyclohexasiloxane:
Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.4. References:
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.
- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.
- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.
Sodium Benzoate
1. Definition Sodium Benzoate:
Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.2. Use:
Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.3. Usage Sodium Benzoate:
When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.4. References:
- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate
- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024
- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics
Elettaria Cardamomum Seed Extract
1. Definition Elettaria Cardamomum Seed Extract:
Elettaria Cardamomum Seed Extract is a natural ingredient derived from the seeds of the cardamom plant, scientifically known as Elettaria cardamomum. It is commonly used in cosmetics for its antioxidant, antimicrobial, and anti-inflammatory properties.2. Use:
Elettaria Cardamomum Seed Extract is often included in skincare products for its ability to protect the skin from environmental stressors and free radicals. It can help to improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has a soothing effect on the skin, making it suitable for sensitive or irritated skin.3. Usage Elettaria Cardamomum Seed Extract:
Elettaria Cardamomum Seed Extract can be found in a variety of cosmetic products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To incorporate this ingredient into your skincare routine, simply apply products containing Elettaria Cardamomum Seed Extract to clean, dry skin as directed by the manufacturer.4. References:
- Bhowmik D, Gopinath H, Kumar BP, Chiranjib, Kumar KPS. Medicinal uses of cardamom (Elettaria cardamomum): a review. J Med Plants Stud. 2014;2(1):42-47.
- Nair R, Chanda S. Antimicrobial activity of Terminalia catappa, Manilkara zapota and Piper betel leaf extract. Indian J Pharm Sci. 2008;70(3):390-393.
- Majeed M, Prakash L. The effect of a novel botanical agent on lipofuscin accumulation in aging skin. J Clin Aesthet Dermatol. 2009;2(11):20-24.
Pyrus Malus (Apple) Fruit Extract
1. Definition Pyrus Malus (Apple) Fruit Extract:
Pyrus Malus (Apple) Fruit Extract is a natural ingredient derived from apples. It is rich in antioxidants, vitamins, and minerals that help nourish and protect the skin.2. Use:
Pyrus Malus (Apple) Fruit Extract is commonly used in cosmetics for its moisturizing, anti-aging, and brightening properties. It helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and even out skin tone.3. Usage Pyrus Malus (Apple) Fruit Extract:
Pyrus Malus (Apple) Fruit Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5%. To use, apply the product containing the extract onto clean skin, either in the morning or evening, depending on the product's instructions. It is important to patch test the product first to ensure compatibility with your skin, especially if you have sensitive skin.4. References:
- Lee, S. H., Lee, S. Y., Son, D. J., Lee, H., Yoo, H. S., Song, S., . . . Hong, J. T. (2013). Inhibitory effect of ursolic acid purified from Origanum majorana L. on the acetylcholinesterase. Molecules, 18(7), 8409-8416.
- Kim, J. H., Kim, Y. H., Song, G. G., & Park, J. J. (2016). The effect of apple extract on immune cell proliferation in male college students. Journal of the Korean Society of Food Science and Nutrition, 45(5), 731-736.
- Kim, M. J., Lee, H. J., & Kim, J. K. (2018). Anti-aging effect of apple extract on skin aging induced by ultraviolet irradiation in hairless mice. Journal of the Korean Society of Cosmetology, 24(3), 513-522.
Rubus Idaeus (Raspberry) Fruit Extract
1. Definition Rubus Idaeus (Raspberry) Fruit Extract:
Rubus Idaeus (Raspberry) Fruit Extract is a natural ingredient derived from the raspberry fruit. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.2. Use:
Raspberry fruit extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It also has anti-inflammatory properties that can soothe irritated skin and reduce redness. Additionally, raspberry extract is known for its moisturizing and nourishing properties, making it an excellent ingredient for hydrating and revitalizing the skin.3. Usage Rubus Idaeus (Raspberry) Fruit Extract:
Raspberry fruit extract can be found in a variety of skincare products, including creams, serums, masks, and lotions. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing raspberry extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with raspberry extract regularly to see the full benefits for the skin.4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
- Afaq, F., & Katiyar, S. K. (2003). Polyphenols: skin photoprotection and inhibition of photocarcinogenesis. Mini reviews in medicinal chemistry, 3(4), 303-308.
- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143.
1,2 Hexanediol
1. Definition 1,2 Hexanediol:
1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.2. Use:
1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.3. Usage 1,2 Hexanediol:
When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.
4. References:
- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook
- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.
Disodium Edta
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Iodopropynyl Butylcarbamate
1. Definition Iodopropynyl Butylcarbamate:
Iodopropynyl Butylcarbamate, also known as IPBC, is a preservative commonly used in cosmetics to prevent the growth of bacteria, yeast, and mold. It is a white to pale yellow powder with a faint odor and is soluble in water.2. Use:
IPBC is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, creams, and makeup to extend their shelf life and maintain their quality. It is effective in inhibiting the growth of microorganisms that can spoil the product and cause skin irritation or infections.3. Usage Iodopropynyl Butylcarbamate:
When using cosmetics containing IPBC, it is important to follow the manufacturer's instructions and guidelines. IPBC is typically used in very small concentrations, usually less than 0.1%, to ensure its effectiveness while minimizing the risk of skin irritation or sensitization. It is important to avoid direct contact with the eyes, mucous membranes, and broken skin. If irritation occurs, discontinue use and consult a healthcare professional.4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of iodopropynyl butylcarbamate. Int J Toxicol. 1995;14 Suppl 1:31-54.
- Cosmetic Ingredient Review Expert Panel. Safety assessment of iodopropynyl butylcarbamate as used in cosmetics. Int J Toxicol. 2010 Jan;29(1 Suppl):182S-202S.
- U.S. Food and Drug Administration. Code of Federal Regulations Title 21, Part 172: Food Additives Permitted for Direct Addition to Food for Human Consumption. Accessed online at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.210
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