Mylan Inotyol

1. Definition Ichthammol:

Ichthammol, also known as ammonium bituminosulfonate, is a dark, tar-like substance derived from shale oil that has been used for centuries in various medicinal applications due to its anti-inflammatory, antibacterial, and antifungal properties.

2. Use:

Ichthammol is commonly used in cosmetics for its ability to draw out impurities and toxins from the skin, making it a popular ingredient in products designed to treat acne, boils, eczema, and other skin conditions. It is also known for its soothing and healing properties, making it effective in reducing inflammation and promoting skin healing.

3. Usage Ichthammol:

When using cosmetics containing ichthammol, it is important to follow the manufacturer's instructions carefully to avoid any potential side effects. It is typically applied topically to the affected area, either as a spot treatment or as part of a larger skincare regimen. Some individuals may experience mild skin irritation or allergic reactions when using products containing ichthammol, so it is recommended to perform a patch test before full application.

4. References:

- Draelos, Z. D. (2016). Cosmeceuticals (3rd ed.). Elsevier Health Sciences.

- Baumann, L. (2009). Cosmetic dermatology: Principles and practice (2nd ed.). McGraw-Hill Medical.

- Pazyar, N., Yaghoobi, R., & Bagherani, N. (2013). A review of applications of Ichthammol in dermatology. Journal of Dermatological Treatment, 24(5), 385-389.

1. Definition Zinc Oxide:

Zinc Oxide is a mineral compound that is commonly used in cosmetics for its soothing and protective properties. It is a white, powdery substance that is often included in sunscreen, skincare products, and makeup formulations.

2. Use:

Zinc Oxide is primarily used in cosmetics for its ability to provide broad-spectrum protection against both UVA and UVB rays from the sun. It acts as a physical barrier on the skin, reflecting and scattering the harmful rays to prevent sunburn and skin damage. In addition to its sun protection benefits, Zinc Oxide also has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Zinc Oxide:

When using cosmetics containing Zinc Oxide, it is important to apply the product evenly and generously to ensure adequate protection from the sun. Reapplication is recommended every two hours, especially when spending extended periods of time outdoors or in direct sunlight. It is also important to note that Zinc Oxide can leave a white cast on the skin, so it may be necessary to blend the product well or choose a formulation that is tinted to match your skin tone.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products (Cosmetic Science and Technology Series). CRC Press.

- Wang, S. Q., & Lim, H. W. (2007). Current status of the sunscreen regulation in the United States: 2011 Food and Drug Administration's final rule on labeling and effectiveness testing. Journal of the American Academy of Dermatology, 66(3), 489-496.

- Nasir, A., Kalam, A., Singh, P., & Sharma, K. (2019). Zinc oxide nanoparticles: a review of their biological synthesis, antimicrobial activity, uptake, translocation and biotransformation in plants. Journal of Materials Science, 54(2), 1016-1042.

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

1. Definition Lanolin:

Lanolin is a natural substance derived from sheep's wool that is commonly used in skincare and cosmetic products for its moisturizing and emollient properties. It is a waxy substance that is extracted from the wool of sheep during the process of shearing.

2. Use:

Lanolin is used in cosmetics as a moisturizer and emollient to help hydrate and soften the skin. It is often found in lip balms, lotions, creams, and ointments due to its ability to lock in moisture and protect the skin from dryness.

3. Usage Lanolin:

Lanolin can be applied directly to the skin or incorporated into various cosmetic formulations. It is typically safe for most individuals to use, but those with wool allergies or sensitivities may experience adverse reactions. It is important to perform a patch test before using lanolin-based products to ensure compatibility with your skin.

Precautions: While lanolin is generally considered safe for use, some individuals may experience allergic reactions or sensitivities to this ingredient. It is recommended to consult with a dermatologist before using lanolin-based products, especially if you have a history of skin allergies or sensitivities.

4. References:

- Paula Begoun, Bryan Barron. "The Original Beauty Bible: Skin Care Facts for Ageless Beauty." Beginning Press, 2003.

- Zoe Diana Draelos. "Cosmetic Dermatology: Products and Procedures." John Wiley & Sons, 2010.

- Raja Sivamani, Jared Jagdeo, Peter Elsner, Howard Maibach. "Cosmetic Formulation of Skin Care Products." CRC Press, 2015.