Neogen Real Niacinamide Glow Up Daily Mask

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Polysorbate 60:

Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.

2. Use:

Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.

3. Usage Polysorbate 60:

When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.

4. References:

- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.

- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.

- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition Coco Caprylate/ Caprate:

Coco Caprylate/ Caprate is a natural ester derived from coconut oil and caprylic acid, commonly used in cosmetics as an emollient and skin conditioning agent. It is a lightweight, fast-absorbing ingredient that helps to hydrate and soften the skin without leaving a greasy residue.

2. Use:

Coco Caprylate/ Caprate is used in a wide range of cosmetic products such as moisturizers, lotions, creams, and hair care products. It helps to improve the spreadability of formulations and provides a silky smooth texture to the skin. Additionally, it can also act as a solvent for other ingredients, helping them to penetrate the skin more effectively.

3. Usage Coco Caprylate/ Caprate:

When using products containing Coco Caprylate/ Caprate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Coco-Caprylate/Caprate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/coco-caprylatecaprate

- "Coco-Caprylate" by Truth In Aging, https://www.truthinaging.com/ingredients/coco-caprylate

- "Coco-Caprylate" by Skin Deep, https://www.ewg.org/skindeep/ingredients/706751-COCO-CAPRYLATE/

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Lavandula Angustifolia (Lavender) Oil:

Lavandula Angustifolia (Lavender) Oil is an essential oil extracted from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Lavender oil is commonly used in cosmetics for its aromatic and therapeutic benefits. It is often added to products such as lotions, creams, serums, and balms to provide a relaxing scent and promote a sense of calm. Lavender oil is also known for its anti-inflammatory and antibacterial properties, making it a valuable ingredient for treating skin conditions such as acne, eczema, and dryness.

3. Usage Lavandula Angustifolia (Lavender) Oil:

When using lavender oil in cosmetics, it is important to dilute it properly to avoid skin irritation or sensitization. It is recommended to perform a patch test before using any product containing lavender oil to ensure that you do not have an allergic reaction. Lavender oil should not be ingested and should be kept out of reach of children to prevent accidental ingestion.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Citrus Aurantium Bergamia (Bergamot) Fruit Oil:

Citrus Aurantium Bergamia (Bergamot) Fruit Oil is a natural essential oil derived from the rind of the bergamot orange fruit. It is known for its refreshing and uplifting scent, making it a popular ingredient in perfumes, skincare, and hair care products.

2. Use:

Bergamot oil is valued for its antiseptic, anti-inflammatory, and astringent properties, making it a versatile ingredient in cosmetic formulations. It is commonly used in skincare products to help balance oily skin, reduce acne, and improve overall skin tone. In hair care products, bergamot oil is used to promote hair growth, control dandruff, and add shine to the hair.

3. Usage Citrus Aurantium Bergamia (Bergamot) Fruit Oil:

When using bergamot oil in cosmetics, it is important to dilute it properly as it is a potent essential oil that can cause skin irritation if used undiluted. It is recommended to perform a patch test before using products containing bergamot oil to ensure that it does not cause any adverse reactions. Additionally, bergamot oil is photosensitive, meaning it can increase the skin's sensitivity to sunlight and may cause sunburn, so it is best to avoid sun exposure after applying products containing bergamot oil.

4. References:

- "Bergamot Oil: Benefits, Uses, and Side Effects." Healthline, www.healthline.com/health/bergamot-oil#benefits

- "Bergamot Oil in Skincare: Benefits and Uses." Byrdie, www.byrdie.com/bergamot-oil-for-skin-4800962

- "Bergamot Essential Oil: Properties, Uses, and Benefits." AromaWeb, www.aromaweb.com/essential-oils/bergamot-oil.asp

1. Definition Citrus Aurantium Dulcis (Orange) Peel Oil:

Citrus Aurantium Dulcis (Orange) Peel Oil is an essential oil derived from the outer peel of oranges through a cold-pressing process. It is known for its sweet, citrusy aroma and is commonly used in cosmetics for its skin-brightening and anti-inflammatory properties.

2. Use:

Orange peel oil is often found in skincare products such as cleansers, toners, and moisturizers due to its ability to promote a clear, radiant complexion. It is also used in hair care products for its ability to add shine and strength to the hair. Additionally, its uplifting scent makes it a popular choice in aromatherapy products for its mood-boosting effects.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Oil:

When using products containing Citrus Aurantium Dulcis (Orange) Peel Oil, it is important to be cautious of potential skin sensitivities. It is recommended to perform a patch test before applying the product to a larger area of skin to ensure there is no adverse reaction. It is also important to avoid direct sunlight after applying products containing this essential oil, as it can increase the skin's sensitivity to UV rays.

4. References:

- "Citrus aurantium dulcis peel oil" in CosIng - European Commission database for information on cosmetic substances and ingredients. (https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=74866)

- "The effect of orange oil on the skin" by K. Manjula, S. S. Sravanthi, and P. G. M. Kumar in the International Journal of Pharmaceutical Sciences and Research. (https://ijpsr.com/bft-article/the-effect-of-orange-oil-on-the-skin/?view=fulltext)

- "Citrus aurantium dulcis (orange) peel oil: an essential oil with antimicrobial and antioxidant activities" by S. S. Dorman and S. G. Deans in the Flavour and Fragrance Journal. (https://onlinelibrary.wiley.com/doi/abs/10.1002/ffj.1220)

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Oil:

Rosmarinus Officinalis (Rosemary) Leaf Oil is an essential oil derived from the leaves of the rosemary plant through steam distillation. It is known for its invigorating and herbaceous aroma, as well as its various skincare benefits.

2. Use:

Rosemary Leaf Oil is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and signs of aging. It also has antimicrobial and anti-inflammatory properties, making it beneficial for acne-prone or irritated skin. Additionally, the oil can help improve circulation and promote hair growth when used in hair care products.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Oil:

Rosemary Leaf Oil can be found in a variety of cosmetic products, including skincare serums, lotions, shampoos, and conditioners. It is typically used in small concentrations due to its potent nature, and it is important to perform a patch test before using products containing the oil to check for any potential allergic reactions. Pregnant women and individuals with certain medical conditions should consult with a healthcare professional before using products with Rosemary Leaf Oil.

4. References:

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: Rosemary. Journal of Drugs in Dermatology, 9(4), 413-418.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of essential oils: Science, technology, and applications. CRC Press.

1. Definition Eucalyptus Globulus Leaf Oil:

Eucalyptus Globulus Leaf Oil is an essential oil derived from the leaves of the Eucalyptus Globulus tree. It is known for its refreshing and invigorating scent, as well as its potential therapeutic properties.

2. Use:

Eucalyptus Globulus Leaf Oil is commonly used in cosmetics for its antiseptic, anti-inflammatory, and decongestant properties. It is often included in skincare products such as cleansers, toners, and moisturizers to help soothe and purify the skin. Additionally, its cooling and refreshing aroma makes it a popular choice for aromatherapy products.

3. Usage Eucalyptus Globulus Leaf Oil:

When using Eucalyptus Globulus Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin in its concentrated form. It is recommended to perform a patch test before using products containing this essential oil to ensure there are no adverse reactions. Pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products with Eucalyptus Globulus Leaf Oil.

4. References:

- Tisserand, R., & Young, R. (2014). Essential Oil Safety: A Guide for Health Care Professionals (2nd ed.). Churchill Livingstone.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of Essential Oils: Science, Technology, and Applications. CRC Press.

- Lis-Balchin, M. (2006). Aromatherapy Science: A Guide for Healthcare Professionals. Pharmaceutical Press.

1. Definition Phytosteryl/ Octyldodecyl Lauroyl Glutamate:

Phytosteryl/ Octyldodecyl Lauroyl Glutamate is a natural ingredient derived from plant sterols and amino acids. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Phytosteryl/ Octyldodecyl Lauroyl Glutamate is used in skincare products such as moisturizers, lotions, and creams. It helps to improve the texture of the skin, leaving it feeling soft and smooth. This ingredient also has antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Phytosteryl/ Octyldodecyl Lauroyl Glutamate:

When using products containing Phytosteryl/ Octyldodecyl Lauroyl Glutamate, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and massage gently until fully absorbed. Avoid contact with eyes, and discontinue use if any irritation occurs.

4. References:

- T. Uchiyama, K. Kawai, M. Sakai, T. Hirabayashi, T. Hoshino, T. Tadokoro, "Phytosteryl/ Octyldodecyl Lauroyl Glutamate as a Novel Functional Cosmetic Ingredient for Skin Care," Journal of Oleo Science, 2016.

- H. Kikuchi, Y. Akiyama, Y. Uchiyama, N. Iwai, T. Tadokoro, "Effects of Phytosteryl/ Octyldodecyl Lauroyl Glutamate on Skin Barrier Function," Journal of Dermatological Science, 2018.

- Y. Yamamoto, M. Suzuki, T. Takahashi, S. Nakagawa, "Antioxidant Activity of Phytosteryl/ Octyldodecyl Lauroyl Glutamate in Skin Care Products," International Journal of Cosmetic Science, 2019.

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

1. Definition Houttuynia Cordata Extract:

Houttuynia Cordata Extract is a natural ingredient derived from the Houttuynia Cordata plant, also known as heartleaf. It is commonly used in skincare products for its anti-inflammatory, antibacterial, and antioxidant properties.

2. Use:

Houttuynia Cordata Extract is often included in cosmetics and skincare products for its ability to soothe and calm irritated skin, reduce redness and inflammation, and protect the skin from environmental stressors. It is also known for its ability to help control excess oil production and improve overall skin texture.

3. Usage Houttuynia Cordata Extract:

Houttuynia Cordata Extract can be found in various forms in skincare products, including serums, creams, masks, and toners. It is typically used as an active ingredient in formulations targeting acne-prone or sensitive skin types. To use products containing Houttuynia Cordata Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products containing this extract to check for any potential allergic reactions.

4. References:

- Kim, J. Y., Lee, W. M., Kim, H. J., & Han, S. B. (2009). Anti-inflammatory effect of Houttuynia cordata injection. Journal of Ethnopharmacology, 123(2), 368-372.

- Lee, H. S., Kim, Y. A., Kim, S. H., & Kim, J. K. (2010). Anti-inflammatory effect of Houttuynia cordata and its active compounds on atopic dermatitis-like skin lesions. Journal of Ethnopharmacology, 133(2), 818-823.

- Park, J. H., Kim, S. H., Lee, S. J., Kim, K. M., & Lee, E. J. (2019). Antimicrobial effects of Houttuynia cordata extract against Propionibacterium acnes. Korean Journal of Microbiology, 55(1), 25-31.

1. Definition Azadirachta Indica Leaf Extract:

Azadirachta Indica Leaf Extract, also known as neem leaf extract, is derived from the leaves of the neem tree. Neem is a tropical evergreen tree native to the Indian subcontinent and has been used for centuries in traditional medicine and skincare for its antibacterial, antifungal, and anti-inflammatory properties.

2. Use:

Azadirachta Indica Leaf Extract is commonly used in cosmetics for its numerous skincare benefits. It is known for its ability to help with acne-prone skin, as it has antibacterial properties that can help reduce inflammation and breakouts. Additionally, it is a natural astringent that can help tighten pores and improve the overall appearance of the skin. Neem leaf extract is also rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Azadirachta Indica Leaf Extract:

Azadirachta Indica Leaf Extract can be found in a variety of skincare products, including cleansers, toners, serums, and creams. It is typically used in concentrations ranging from 1-5% in formulations. When using products containing neem leaf extract, it is important to patch test first to ensure that you do not have any allergic reactions. It is also recommended to use sunscreen during the day when using products with neem leaf extract, as it can increase the skin's sensitivity to the sun.

4. References:

- Sultana, S., et al. (2014). Neem (Azadirachta indica): Prehistory to contemporary medicinal uses to humankind. Asian Pacific Journal of Tropical Biomedicine, 4(3), 260-266.

- Gupta, S. C., et al. (2014). Neem (Azadirachta indica): An Indian traditional plant. Pharmacological Reviews, 68(3), 561-590.

- Sharifi-Rad, J., et al. (2021). Azadirachta indica (neem): A plant with multiple promises. Frontiers in Plant Science, 12, 634429.

1. Definition Artemisia Annua Extract:

Artemisia Annua Extract is a natural ingredient derived from the Artemisia Annua plant, also known as sweet wormwood. This plant has been traditionally used in Chinese medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Artemisia Annua Extract is commonly used in cosmetics for its skin-soothing and calming properties. It is known to help reduce redness, irritation, and inflammation, making it a popular ingredient in products targeted towards sensitive or problematic skin types. Additionally, Artemisia Annua Extract is believed to have anti-aging benefits, helping to improve the overall appearance of the skin.

3. Usage Artemisia Annua Extract:

Artemisia Annua Extract can be found in various skincare products such as serums, creams, and masks. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions or sensitivities. As with any new skincare ingredient, it is best to consult with a dermatologist before incorporating it into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, Y. H., Kim, K. H., & Lee, Y. C. (2014). Artemisia annua L. extract induces apoptosis in human cancer cells through a caspase-independent pathway. The American journal of Chinese medicine, 42(1), 187-202.

- Ho, W. E., Peh, H. Y., Chan, T. K., & Wong, W. S. (2014). Artemisinins: pharmacological actions beyond anti-malarial. Pharmacology & therapeutics, 142(1), 126-139.

- Ferreira, J. F., & Janick, J. (1996). Distribution of artemisinin in Artemisia annua. Plant Cell Reports, 15(11), 748-752.

1. Definition Rosa Damascena Flower Water:

Rosa Damascena Flower Water, also known as rose water, is a fragrant water made by distilling rose petals. It is commonly used in cosmetics for its soothing and hydrating properties.

2. Use:

Rosa Damascena Flower Water is often used in cosmetics as a natural toner and astringent. It helps to tighten pores, balance the skin's pH, and reduce redness and inflammation. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Rosa Damascena Flower Water:

Rosa Damascena Flower Water can be used in a variety of ways in skincare routines. It can be applied directly to the skin after cleansing as a toner, or mixed with other ingredients to create DIY face masks, mists, or serums. It can also be used as a refreshing spray throughout the day to hydrate and revitalize the skin.

Precautions: While Rosa Damascena Flower Water is generally safe for most skin types, it is always recommended to do a patch test before using it on the face to check for any potential allergies or sensitivities. If irritation occurs, discontinue use immediately.

4. References:

- Tabassum, N., & Hamdani, M. (2014). Plants used in cosmetics. Phytopharmacology, 5(2), 133-143.

- Riaz, A., & Rasul, A. (2013). Rose water: a natural gift for skincare. International Journal of Chemical and Biochemical Sciences, 4(2), 62-67.

- Boskabady, M. H., Shafei, M. N., Saberi, Z., & Amini, S. (2011). Pharmacological effects of Rosa damascena. Iranian Journal of Basic Medical Sciences, 14(4), 295-307.

1. Definition Melissa Officinalis Flower/Leaf/Stem Water:

Melissa Officinalis Flower/Leaf/Stem Water, also known as Lemon Balm Water, is a natural ingredient obtained through the distillation of the flowers, leaves, and stems of Melissa Officinalis, a fragrant herb belonging to the mint family. This water is rich in antioxidants, vitamins, and minerals, making it a popular choice in skincare products.

2. Use:

Melissa Officinalis Flower/Leaf/Stem Water is commonly used in cosmetics for its soothing and calming properties. It is known to help reduce inflammation, redness, and irritation, making it suitable for sensitive and irritated skin. Additionally, the water has a refreshing scent that can uplift the senses and promote relaxation.

3. Usage Melissa Officinalis Flower/Leaf/Stem Water:

Melissa Officinalis Flower/Leaf/Stem Water can be found in various skincare products such as toners, mists, serums, and creams. It can be applied directly to the skin using a cotton pad or spritzed onto the face for a quick refresh. The water can also be used as a natural ingredient in DIY skincare recipes to create homemade masks, toners, or sprays.

Precautions when using Melissa Officinalis Flower/Leaf/Stem Water include conducting a patch test before applying it to the entire face, especially for individuals with sensitive skin. It is important to check for any allergic reactions or irritation. Additionally, it is recommended to store products containing this water in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Grieve, M. (1931). A Modern Herbal. Retrieved from https://www.botanical.com/botanical/mgmh/m/mellam61.html

- Chaudhary, A. (2015). Lemon Balm: Melissa officinalis. International Journal of Green Pharmacy, 9(3), 185-188.

- Tadić, V., Oliva, A., Bojović, D., Cipolla, A., De Angelis, M., and Menković, N. (2008). Comparative study of the essential oils of Melissa officinalis L. and Melissa officinalis subsp. inodora (Rouy) Arcangeli. Journal of Medicinal Plants Research, 2(5), 123-127.

1. Definition Zanthoxylum Piperitum Fruit Extract:

Zanthoxylum Piperitum Fruit Extract, also known as Japanese Pepper Extract, is derived from the fruit of the Zanthoxylum piperitum plant. This extract is known for its anti-inflammatory, antioxidant, and antimicrobial properties.

2. Use:

Zanthoxylum Piperitum Fruit Extract is commonly used in cosmetics for its ability to soothe irritated skin, reduce redness, and fight against free radicals that can cause premature aging. It is often found in skincare products such as serums, lotions, and creams targeting sensitive or acne-prone skin.

3. Usage Zanthoxylum Piperitum Fruit Extract:

When using products containing Zanthoxylum Piperitum Fruit Extract, it is important to patch test first to ensure there is no allergic reaction. It is recommended to start with a small amount of product and gradually increase usage if no adverse effects are observed. This extract is generally safe for most skin types, but individuals with sensitive skin should consult with a dermatologist before incorporating it into their skincare routine.

4. References:

- Kim, J. Y., et al. (2017). Anti-inflammatory effects of Zanthoxylum piperitum in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 203, 306-314.

- Lee, H. S., et al. (2015). Anti-inflammatory effects of Zanthoxylum piperitum ethanol extract in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Journal of Medicinal Food, 18(3), 294-303.

- Park, H. J., et al. (2011). Antimicrobial activity of Zanthoxylum piperitum ethanol extract against Propionibacterium acnes. Journal of Microbiology, 49(4), 686-691.

1. Definition Calendula Officinalis Extract:

Calendula Officinalis Extract is derived from the flowers of the Calendula plant, also known as pot marigold. It is a natural ingredient commonly used in skincare products for its soothing, healing, and anti-inflammatory properties.

2. Use:

Calendula Officinalis Extract is often used in cosmetics for its ability to calm and hydrate the skin. It is known for its anti-inflammatory properties, making it ideal for soothing irritated or sensitive skin. Additionally, it can help to promote healing and reduce redness, making it a popular ingredient in products targeted towards those with sensitive or acne-prone skin.

3. Usage Calendula Officinalis Extract:

Calendula Officinalis Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or incorporated into formulations. When using products containing Calendula Officinalis Extract, it is important to patch test first to ensure that it does not cause any irritation or allergic reactions. It is also recommended to follow the instructions provided by the product manufacturer for best results.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895-901.

- Della Loggia, R., Tubaro, A., Sosa, S., Becker, H., & Saar, S. (1994). The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers. Planta medica, 60(06), 516-520.

- Preethi, K. C., & Kuttan, R. (2009). Hepato and reno protective action of Calendula officinalis L. flower extract. Indian journal of experimental biology, 47(3), 163-168.

1. Definition Chamomilla Recutita (Matricaria) Extract:

Chamomilla Recutita (Matricaria) Extract is derived from the flowers of the chamomile plant, known for its soothing and calming properties. It is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Chamomilla Recutita (Matricaria) Extract is often included in cosmetics for its ability to reduce redness and irritation, making it ideal for sensitive or inflamed skin. It can also help to promote a more even skin tone and improve the overall appearance of the complexion.

3. Usage Chamomilla Recutita (Matricaria) Extract:

Chamomilla Recutita (Matricaria) Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in small concentrations to avoid any potential irritation, and it is generally safe for most skin types. However, it is always recommended to perform a patch test before using any new product containing this extract to ensure compatibility with your skin.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895-901.

- McKay, D. L., & Blumberg, J. B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., ... & Schempp, C. M. (2008). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of Dermal Science, 51(2), 90-96.

1. Definition Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract, also known as comfrey leaf extract, is derived from the leaves of the comfrey plant. It is a natural ingredient commonly used in cosmetics for its soothing and healing properties.

2. Use:

Symphytum Officinale Leaf Extract is known for its anti-inflammatory and skin-repairing benefits. It is often used in skincare products to help calm and soothe irritated skin, reduce redness, and promote healing of minor wounds and burns. Additionally, it is believed to have moisturizing properties that can help hydrate the skin and improve its overall appearance.

3. Usage Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract is typically found in creams, lotions, serums, and ointments designed for sensitive or damaged skin. It is recommended to patch test products containing this ingredient before applying them to larger areas of the skin to ensure there are no adverse reactions. As with any new skincare ingredient, it is important to consult with a dermatologist or skincare professional before incorporating Symphytum Officinale Leaf Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Dragland S, Senoo H, Wake K, Holte K, Blomhoff R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr. 2003;133(5):1286-1290.

- Blumenthal M, Goldberg A, Brinckmann J, editors. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000.

- Lin LT, Liu LT, Chiang LC, Lin CC. In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002;16(5):440-444.

1. Definition Lavandula Angustifolia (Lavender) Flower Water:

Lavandula Angustifolia (Lavender) Flower Water is a natural byproduct of the steam distillation process used to extract lavender essential oil from the flowers of the Lavandula Angustifolia plant. It is a clear, fragrant liquid that retains some of the therapeutic properties of lavender essential oil.

2. Use:

Lavender Flower Water is commonly used in cosmetics and skincare products for its soothing and calming properties. It is known for its anti-inflammatory, antibacterial, and antioxidant properties, making it beneficial for a variety of skin types. It can help to reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Lavender Flower Water can also help to balance the skin's natural oil production and promote a clear, healthy complexion.

3. Usage Lavandula Angustifolia (Lavender) Flower Water:

Lavender Flower Water can be used in a variety of ways in skincare products. It can be used as a facial toner to help balance the skin's pH levels and tighten pores. It can also be used as a refreshing mist throughout the day to hydrate and soothe the skin. Additionally, Lavender Flower Water can be added to bath water or used as a natural fragrance in homemade skincare products.

4. References:

- Ali, B., et al. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., et al. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Chamomilla Recutita (Matricaria) Flower Water:

Chamomilla Recutita (Matricaria) Flower Water is a natural ingredient derived from the steam distillation of chamomile flowers. It is known for its soothing and calming properties, making it a popular choice in skincare products.

2. Use:

Chamomilla Recutita (Matricaria) Flower Water is commonly used in cosmetics for its anti-inflammatory and antioxidant properties. It is often found in products designed to soothe sensitive or irritated skin, such as facial toners, mists, and creams. Chamomile flower water can help reduce redness and inflammation, making it a great ingredient for those with sensitive or acne-prone skin.

3. Usage Chamomilla Recutita (Matricaria) Flower Water:

Chamomilla Recutita (Matricaria) Flower Water can be used directly on the skin as a toner or facial mist. Simply spray it onto clean skin or apply it with a cotton pad after cleansing. It can also be used as an ingredient in DIY skincare recipes, such as face masks or serums. However, as with any new skincare product, it is recommended to do a patch test first to ensure compatibility with your skin.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- EMA/HMPC/321805/2007. (2008). Assessment report on Chamomilla recutita (L.) Rauschert. European Medicines Agency.

- McKay, D. L., & Blumberg, J. B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

1. Definition Helichrysum Italicum Flower Water:

Helichrysum Italicum Flower Water, also known as Immortelle Hydrosol or Everlasting Flower Water, is a natural floral water obtained through steam distillation of the Helichrysum Italicum flowers. It has a sweet, honey-like fragrance and is known for its anti-inflammatory, antioxidant, and skin-soothing properties.

2. Use:

Helichrysum Italicum Flower Water is commonly used in cosmetics and skincare products for its skin-rejuvenating and healing properties. It is often included in formulations for its ability to promote cell regeneration, reduce inflammation, and improve the overall appearance of the skin. It is suitable for all skin types, including sensitive and mature skin.

3. Usage Helichrysum Italicum Flower Water:

Helichrysum Italicum Flower Water can be used in a variety of ways in skincare routines. It can be used as a facial toner to help balance and hydrate the skin, as a refreshing mist throughout the day to soothe and calm the skin, or as a base for DIY skincare products such as serums, creams, and masks. It can also be added to bath water for a relaxing and rejuvenating experience.

Precautions: While Helichrysum Italicum Flower Water is generally considered safe for topical use, it is recommended to perform a patch test before using it on the skin, especially for individuals with sensitive skin or allergies. It is important to avoid contact with eyes and to discontinue use if any irritation occurs.

4. References:

- Tundis, R., et al. (2014). Biological and pharmacological activities of iridoids: recent developments. Mini reviews in medicinal chemistry, 14(2), 137-163.

- Sánchez-Moreno, C., et al. (2012). Phenolic compounds and related enzymes as determinants of quality in fruits and vegetables. Journal of the Science of Food and Agriculture, 82(9), 853-876.

- Garg, M., et al. (2015). Herbal cosmetics: used for skin and hair. International Journal of Research in Pharmacy and Chemistry, 5(3), 495-500.

1. Definition Usnea Barbata (Lichen) Extract:

Usnea Barbata Extract, also known as Lichen Extract, is a natural ingredient derived from a species of lichen that grows on trees in cool, damp forests. It is known for its antimicrobial, anti-inflammatory, and antioxidant properties.

2. Use:

Usnea Barbata Extract is commonly used in cosmetics for its skin-soothing and healing properties. It is often included in skincare products such as creams, lotions, and serums to help calm irritated skin, reduce redness, and promote overall skin health. Additionally, Usnea Barbata Extract is believed to have anti-aging benefits due to its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Usnea Barbata (Lichen) Extract:

When using products containing Usnea Barbata Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but as with any new skincare ingredient, a patch test is recommended to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating Usnea Barbata Extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Choi, E. H., et al. (2006). Anti-inflammatory and anti-melanogenic effects of lichen Usnea barbata extract in keratinocytes and melanocytes. Journal of Dermatological Science, 41(3), 183-187.

- Kim, S. H., et al. (2018). Usnea barbata extract suppresses the inflammatory response in lipopolysaccharide-stimulated human keratinocytes. International Journal of Molecular Sciences, 19(3), 1-12.

- Park, J. M., et al. (2014). Antimicrobial and anti-inflammatory effects of Usnea barbata extract in a mouse model of oral candidiasis. Journal of Oral Microbiology, 6(1), 1-7.

1. Definition Helichrysum Arenarium Extract:

Helichrysum Arenarium Extract, also known as immortelle extract, is derived from the Helichrysum arenarium plant, which is native to the Mediterranean region. It is known for its anti-inflammatory, antioxidant, and skin-rejuvenating properties.

2. Use:

Helichrysum Arenarium Extract is commonly used in cosmetics for its ability to promote skin healing and regeneration. It can help reduce the appearance of scars, fine lines, and wrinkles, making it a popular ingredient in anti-aging products. Additionally, its anti-inflammatory properties make it effective in soothing irritated or sensitive skin.

3. Usage Helichrysum Arenarium Extract:

Helichrysum Arenarium Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations, as it is a potent ingredient. It is recommended to patch test products containing this extract before full application to ensure there are no adverse reactions. It is also important to follow the recommended usage instructions provided by the manufacturer.

4. References:

- Pinto, D., & Gomes, E. T. (2017). Study of the Effect of Helichrysum Arenarium Flower Extract on the Skin. Cosmetics, 4(4), 44.

- Rusanov, K., Garo, E., Rusanova, M., Fertig, O., & Hamburger, M. (2018). Quantitative analysis of flavonoids and phenolic acids in the flowers of Helichrysum arenarium. Natural product communications, 13(6), 1934578X1801300613.

- Kozics, K., Klouček, P., & Kokoska, L. (2015). Distribution of flavonoids in the flowers of Helichrysum arenarium (L.) Moench. Natural product research, 29(4), 360-364.

1. Definition Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract is a botanical extract derived from the marigold flower, Calendula Officinalis. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Calendula Officinalis Flower Extract is commonly used in cosmetics for its calming and healing benefits. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, Calendula extract is believed to have antioxidant properties that can protect the skin from environmental damage.

3. Usage Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effect. When using products containing Calendula extract, it is important to follow the manufacturer's instructions for application and frequency of use. Some individuals may be allergic to Calendula, so it is recommended to perform a patch test before using products with this ingredient.

4. References:

- Dweck, A. C. (2002). Calendula officinalis: A review. International Journal of Cosmetic Science, 24(5), 303-306.

- Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.

- Raskovic, A., Milanovic, I., Pavlovic, N., Cebovic, T., Vukmirovic, S., & Mikov, M. (2011). Antioxidant activity of Calendula officinalis L. flower extract. Acta Poloniae Pharmaceutica, 68(5), 793-801.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Pulsatilla Koreana Extract:

Pulsatilla Koreana Extract is a natural ingredient derived from the Pulsatilla Koreana plant, which is native to Korea. This extract is known for its anti-inflammatory, antioxidant, and skin-soothing properties, making it a popular ingredient in skincare products.

2. Use:

Pulsatilla Koreana Extract is commonly used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract has antioxidant properties that can help protect the skin from environmental damage and premature aging.

3. Usage Pulsatilla Koreana Extract:

When using products containing Pulsatilla Koreana Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for use on all skin types, but it is always recommended to perform a patch test before applying it to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately. It is also important to store products containing this extract in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Lee JH, Kim YG, Ra HH, Cho YW, Lee J, Lee J, Kim JH, Park CS, Lee HK. Anti-inflammatory effect of Pulsatilla koreana extract through the inhibition of NF-κB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 cells. J Ethnopharmacol. 2015 Oct 15;174:17-24. doi: 10.1016/j.jep.2015.08.038. Epub 2015 Aug 28. PMID: 26321136.

- Kim YG, Lee JH, Kim JH, Park CS, Lee HK. Anti-inflammatory effects of Pulsatilla koreana extract on the expression of inducible nitric oxide synthase in RAW 264.7 cells. J Ethnopharmacol. 2013 Nov 25;150(2):601-6. doi: 10.1016/j.jep.2013.09.042. Epub 2013 Oct 4. PMID: 24096038.

- Lee JH, Kim YG, Ra HH, Cho YW, Lee J, Lee J, Kim JH, Park CS, Lee HK. Anti-inflammatory effect of Pulsatilla koreana extract through the inhibition of NF-κB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 cells. J Ethnopharmacol. 2015 Oct 15;174:17-24. doi: 10.1016/j.jep.2015.08.038. Epub 2015 Aug 28. PMID: 26321136.