Name: Perrigo Ketoconazole Shampoo, 2%
Brand: Perrigo
Rating: 5 (6 reviews)

Ketoconazole

1. Definition Ketoconazole:

Ketoconazole is an antifungal medication commonly used in the treatment of fungal infections on the skin, hair, and nails. It works by inhibiting the growth of fungi that cause infections.

2. Use:

Ketoconazole is often used in cosmetic products, such as shampoos and creams, to treat conditions like dandruff, seborrheic dermatitis, and fungal acne. It is effective in reducing the itching, flaking, and inflammation associated with these conditions.

3. Usage Ketoconazole:

When using cosmetic products containing ketoconazole, it is important to follow the instructions provided by the manufacturer or healthcare provider. Typically, the product is applied to the affected area and left on for a few minutes before rinsing off. It is important to avoid getting the product in the eyes, mouth, or broken skin. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Elewski BE. Clinical pearl: ketoconazole foam, 2%, for the treatment of seborrheic dermatitis. Cutis. 2007;79(5):393-396.

- Gupta AK, Ryder JE, Nicol K, Cooper EA. Superficial fungal infections: an update on pityriasis versicolor, seborrheic dermatitis, tinea capitis, and onychomycosis. Clin Dermatol. 2003;21(5):417-429.

- Berg D, Otley CC. Management of seborrheic dermatitis and pityriasis rosea. Am Fam Physician. 2000;61(9):2703-2710.

Coconut Fatty Acid Diethanolamide

Ingredient data is being updated. Please check back later.

Disodium Laureth Sulfosuccinate

Function: Solvent to dissolve substances insoluble in water, Sufactant, Foam Boosting, Foaming

1. Definition Disodium Laureth Sulfosuccinate:

Disodium Laureth Sulfosuccinate is a mild surfactant that is commonly used in cosmetics and personal care products. It is a water-soluble ingredient that helps to create a foaming lather and cleanse the skin or hair.

2. Use:

Disodium Laureth Sulfosuccinate is often found in shampoos, body washes, facial cleansers, and other skincare products. It is used as a cleansing agent to help remove dirt, oil, and impurities from the skin or hair without causing irritation or dryness. Due to its mild nature, it is suitable for sensitive skin types.

3. Usage Disodium Laureth Sulfosuccinate:

When using products containing Disodium Laureth Sulfosuccinate, it is important to follow the instructions on the packaging. Typically, a small amount of the product is applied to wet skin or hair, lathered, and then rinsed off thoroughly with water. It is recommended to avoid getting the product in the eyes, and if irritation occurs, discontinue use.

4. References:

- "Safety Assessment of Disodium Laureth Sulfosuccinate and Sodium Laureth Sulfosuccinate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (https://www.cir-safety.org/sites/default/files/sulfosucc.pdf)

- "Disodium Laureth Sulfosuccinate" on the Environmental Working Group's Skin Deep Cosmetics Database. (https://www.ewg.org/skindeep/ingredients/706735-DISODIUM_LAURETH_SULFOSUCCINATE/)

- "Disodium Laureth Sulfosuccinate: A Mild Surfactant for Personal Care Formulations" by Croda International. (https://www.crodapersonalcare.com/en-gb/discover/personal-care/disodium-laureth-sulfosuccinate-a-mild-surfactant-for-personal-care-formulations)

FD & C Red No. 40

1. Definition Fd&C Red No. 40 (Ci 16035):

Fd&C Red No. 40 (Ci 16035) is a synthetic dye that is commonly used in cosmetics to impart a red color to various products.

2. Use:

Fd&C Red No. 40 is primarily used as a colorant in cosmetics such as lipsticks, blushes, eyeshadows, and nail polishes. It is known for its vibrant and long-lasting red hue, making it a popular choice for adding a pop of color to beauty products.

3. Usage Fd&C Red No. 40 (Ci 16035):

When using cosmetics containing Fd&C Red No. 40, it is important to be aware of any potential allergic reactions or sensitivities. Some individuals may experience skin irritation or allergic reactions when exposed to this dye, so it is recommended to perform a patch test before applying products with Fd&C Red No. 40 to a larger area of the skin. Additionally, it is advisable to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product.

4. References:

- U.S. Food and Drug Administration. (2021). Color Additives Permitted for Use in Cosmetics. Retrieved from https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics

- Cosmetic Ingredient Review. (2011). Final Report on the Safety Assessment of Red 40. Retrieved from https://www.cir-safety.org/sites/default/files/PR40.pdf

- Personal Care Products Council. (n.d.). Red 40. Retrieved from https://www.personalcarecouncil.org/Color-Additives/Red-40

Hydrochloric Acid

Function: pH adjusting agent, pH adjusting agent

1. Definition Hydrochloric Acid:

Hydrochloric Acid, also known as muriatic acid, is a strong mineral acid commonly used in various industries, including cosmetics. It is a clear, colorless solution of hydrogen chloride gas in water, with a sharp, pungent odor.

2. Use:

Hydrochloric Acid is used in cosmetics as a pH adjuster and a chemical exfoliant. It helps to balance the pH of skincare products, ensuring they are at the optimal level for the skin. Additionally, it can help to exfoliate the skin by removing dead skin cells, promoting cell turnover, and revealing smoother, brighter skin.

3. Usage Hydrochloric Acid:

When using cosmetics containing Hydrochloric Acid, it is important to follow the instructions provided by the manufacturer carefully. It is recommended to perform a patch test before applying the product to the entire face to check for any potential irritation or allergic reactions. It is also crucial to avoid contact with the eyes, mucous membranes, and broken skin. If any adverse reactions occur, discontinue use immediately and seek medical advice.

4. References:

- Skin Inc. "Hydrochloric Acid in Cosmetics: What You Need to Know." www.skininc.com

- The Dermatology Review. "The Benefits of Hydrochloric Acid in Skincare." www.thedermreview.com

- Cosmetics Info. "Hydrochloric Acid." www.cosmeticsinfo.org

Imidurea

Ingredient data is being updated. Please check back later.

Laurdimonium Hydroxypropyl Hydrolyzed Collagen

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Laurdimonium Hydroxypropyl Hydrolyzed Collagen:

Laurdimonium Hydroxypropyl Hydrolyzed Collagen is a conditioning agent used in cosmetics and personal care products. It is a quaternized collagen derivative that is water-soluble and has excellent film-forming properties.

2. Use:

Laurdimonium Hydroxypropyl Hydrolyzed Collagen is commonly used in hair care products such as shampoos, conditioners, and hair masks. It helps to improve the strength and elasticity of the hair, making it more manageable and reducing breakage. In skincare products, it can help to improve the hydration and firmness of the skin, making it appear smoother and more youthful.

3. Usage Laurdimonium Hydroxypropyl Hydrolyzed Collagen:

When using products containing Laurdimonium Hydroxypropyl Hydrolyzed Collagen, it is important to follow the instructions provided on the product packaging. It is generally safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using it on a larger area of skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2012). Final report on the safety assessment of hydrolyzed collagen. International Journal of Toxicology, 31(2 Suppl), 85S-90S.

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Lee, S. J., & Thagard, M. (2004). The effects of a hydrolyzed collagen-based ingredient on skin moisture retention. Journal of Cosmetic Dermatology, 3(2), 88-93.

Peg 120 Methyl Glucose Dioleate

Function: Emulsifying, Sufactant

1. Definition Peg 120 Methyl Glucose Dioleate:

Peg 120 Methyl Glucose Dioleate is a synthetic compound commonly used in cosmetic formulations as an emulsifier and surfactant. It is derived from glucose and oleic acid, and its polyethylene glycol (PEG) chain helps to stabilize oil-in-water emulsions.

2. Use:

Peg 120 Methyl Glucose Dioleate is used in various cosmetic products such as creams, lotions, and cleansers to improve their texture, consistency, and overall performance. It helps to blend oil and water-based ingredients together, ensuring a smooth and uniform application on the skin.

3. Usage Peg 120 Methyl Glucose Dioleate:

When using products containing Peg 120 Methyl Glucose Dioleate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. Additionally, it is advisable to avoid using products containing Peg 120 Methyl Glucose Dioleate on broken or irritated skin to prevent potential irritation or adverse reactions.

4. References:

- "Safety Assessment of PEG-120 Methyl Glucose Dioleate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (https://www.cir-safety.org/sites/default/files/PEG%20120%20Methyl%20Glucose%20Dioleate.pdf)

- "PEG-120 Methyl Glucose Dioleate" by Cosmetics Info. (https://cosmeticsinfo.org/ingredient/peg-120-methyl-glucose-dioleate)

- "PEG-120 Methyl Glucose Dioleate" by Truth in Aging. (https://www.truthinaging.com/ingredients/peg-120-methyl-glucose-dioleate)

Purified Water

1. Definition Mineral Water:

Mineral water in cosmetics refers to water sourced from natural mineral springs that contains various minerals and trace elements beneficial for the skin.

2. Use:

Mineral water is commonly used in cosmetics as a hydrating and refreshing ingredient. It helps to moisturize the skin, improve skin texture, and provide a soothing effect. Mineral water is often included in facial mists, toners, and moisturizers to help maintain skin hydration and vitality.

3. Usage Mineral Water:

Mineral water can be used in various ways in skincare routines. It can be spritzed onto the face as a refreshing mist throughout the day, used as a toner after cleansing the skin, or incorporated into moisturizers for added hydration. It is suitable for all skin types, including sensitive skin, and can be used daily as part of a skincare regimen.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Loden, M., & Maibach, H. I. (2012). Dry skin and moisturizers: chemistry and function. CRC Press.

Sodium Chloride

Other Names: NaCl; Natrum muriaticum

Function: Masking, Viscosity Controlling, Bulking Agent

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

Sodium Hydroxide

Other Names: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Sodium Lauryl Ether Sulphate

Ingredient data is being updated. Please check back later.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
6	-	Ketoconazole
-	-	Coconut Fatty Acid Diethanolamide
2	B	Disodium Laureth Sulfosuccinate (Solvent to dissolve substances insoluble in water, Sufactant, Foam Boosting, Foaming)
3 6	-	FD & C Red No. 40
2	-	Hydrochloric Acid (pH adjusting agent, pH adjusting agent)
-	-	Imidurea
1	-	Laurdimonium Hydroxypropyl Hydrolyzed Collagen (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1 3	A	Peg 120 Methyl Glucose Dioleate (Emulsifying, Sufactant)	Cleansing
1	-	Purified Water
1	-	Sodium Chloride (Masking, Viscosity Controlling, Bulking Agent)
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
-	-	Sodium Lauryl Ether Sulphate

Perrigo Ketoconazole Shampoo, 2%

Ingredients

Analysis results of Ingredients

Ingredient List