Rhonda Allison BHA Refine Gel

1. Definition Azelaic Acid:

Azelaic acid is a naturally occurring dicarboxylic acid found in grains like barley, wheat, and rye. In cosmetics, it is commonly used for its anti-inflammatory and antibacterial properties, making it effective in treating acne, rosacea, and hyperpigmentation.

2. Use:

Azelaic acid is used in skincare products such as creams, gels, and serums to help improve the appearance of skin by reducing inflammation, unclogging pores, and fading dark spots. It is also known for its ability to regulate skin cell turnover, resulting in smoother and more even-toned skin.

3. Usage Azelaic Acid:

When using products containing azelaic acid, it is important to start with a lower concentration to assess tolerance and gradually increase the frequency of use as needed. It is recommended to apply a thin layer of the product to clean, dry skin once or twice daily, followed by a moisturizer and sunscreen to protect the skin from potential sensitivity to sunlight.

4. References:

- Del Rosso, J. Q. (2013). Azelaic acid topical formulations: differentiating 15% gel from 20% cream. Journal of Drugs in Dermatology, 12(9), 1012-1016.

- Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A., Araviiskaia, E., Barona Cabal, M. I., ... & Zouboulis, C. C. (2018). Practical management of acne for clinicians: an international consensus from the Global Alliance to Improve Outcomes in Acne. Journal of the American Academy of Dermatology, 78(2), S1-S23.

- Kircik, L. H. (2014). Azelaic acid 15% gel: in the treatment of papulopustular rosacea. Journal of Clinical and Aesthetic Dermatology, 7(12), 27-29.

1. Definition Lactic Acid, L:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is often used in skincare products for its exfoliating and moisturizing properties.

2. Use:

Lactic acid is commonly used in cosmetics and skincare products for its ability to gently exfoliate the skin, promoting cell turnover and revealing smoother, brighter skin. It can also help to improve the skin's texture, reduce the appearance of fine lines and wrinkles, and even out skin tone.

3. Usage Lactic Acid, L:

When using skincare products containing lactic acid, it is important to start with a lower concentration and gradually increase as your skin becomes accustomed to the ingredient. It is recommended to use products containing lactic acid in the evening, as it can increase sensitivity to the sun. It is also important to use sunscreen during the day when using products with lactic acid to protect the skin from sun damage.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327.

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Hydroxypropyl Methylcellulose:

Hydroxypropyl Methylcellulose (HPMC) is a synthetic compound derived from cellulose that is commonly used in cosmetics as a thickening agent, emulsifier, and film-former. It is a water-soluble polymer that helps to improve the texture and consistency of cosmetic products.

2. Use:

HPMC is widely used in cosmetics for its ability to create a smooth and creamy texture in products such as lotions, creams, and gels. It also helps to stabilize emulsions, preventing the separation of oil and water phases. Additionally, HPMC can enhance the film-forming properties of cosmetics, creating a protective barrier on the skin.

3. Usage Hydroxypropyl Methylcellulose:

When using products containing HPMC, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products with HPMC to their entire face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Kim, S., et al. (2017). Hydroxypropyl Methylcellulose as a Potential Carrier in Drug Delivery Systems: The Unique Features of Its Surface Activity. Journal of Pharmaceutical Sciences, 106(6), 1956-1963.

- Lopes, M., et al. (2019). Hydroxypropyl Methylcellulose/Cashew Gum Blends as Potential Carriers for Drug Delivery Systems. Carbohydrate Polymers, 216, 1-9.

- Ribeiro, L., et al. (2020). Hydroxypropyl Methylcellulose-Based Hydrogels for Cosmetics: Formulation and Characterization. International Journal of Cosmetic Science, 42(1), 89-98.

1. Definition Lavandula Angustifolia (Lavender) Oil:

Lavandula Angustifolia (Lavender) Oil is an essential oil extracted from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Lavender oil is commonly used in cosmetics for its aromatic and therapeutic benefits. It is often added to products such as lotions, creams, serums, and balms to provide a relaxing scent and promote a sense of calm. Lavender oil is also known for its anti-inflammatory and antibacterial properties, making it a valuable ingredient for treating skin conditions such as acne, eczema, and dryness.

3. Usage Lavandula Angustifolia (Lavender) Oil:

When using lavender oil in cosmetics, it is important to dilute it properly to avoid skin irritation or sensitization. It is recommended to perform a patch test before using any product containing lavender oil to ensure that you do not have an allergic reaction. Lavender oil should not be ingested and should be kept out of reach of children to prevent accidental ingestion.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Citrus Grandis (Grapefruit) Peel Oil:

Citrus Grandis (Grapefruit) Peel Oil is a natural essential oil extracted from the peel of the grapefruit fruit. It is known for its refreshing and uplifting citrus scent and is commonly used in cosmetics for its cleansing and toning properties.

2. Use:

Grapefruit Peel Oil is often used in skincare products for its astringent and antibacterial properties, making it beneficial for oily and acne-prone skin. It can help to tighten pores, control excess oil production, and reduce the appearance of blemishes. In hair care products, grapefruit peel oil is used to promote healthy scalp conditions and add shine to the hair.

3. Usage Citrus Grandis (Grapefruit) Peel Oil:

Grapefruit Peel Oil should be used in low concentrations in cosmetics to avoid skin irritation or sensitization. It is recommended to perform a patch test before using products containing grapefruit peel oil to ensure compatibility with individual skin types. Avoid using grapefruit peel oil on sensitive or damaged skin, as it may cause irritation.

4. References:

- "Grapefruit Essential Oil: Uses, Benefits, and Precautions." https://www.healthline.com/health/grapefruit-essential-oil

- "Citrus Grandis (Grapefruit) Peel Oil." https://www.ewg.org/skindeep/ingredients/702418-CITRUS_GRANDIS_(GRAPEFRUIT)_PEEL_OIL/

- "The Benefits of Grapefruit Essential Oil." https://www.verywellhealth.com/grapefruit-essential-oil-benefits-4173287

1. Definition Mentha Viridis (Spearmint) Leaf Oil:

Mentha Viridis (Spearmint) Leaf Oil is an essential oil derived from the steam distillation of the leaves of the spearmint plant. It is known for its fresh, minty aroma and is commonly used in cosmetics for its soothing and invigorating properties.

2. Use:

Mentha Viridis (Spearmint) Leaf Oil is often used in cosmetics for its refreshing scent and cooling sensation on the skin. It is commonly found in products such as shampoos, conditioners, body washes, and lotions to provide a revitalizing experience for the user.

3. Usage Mentha Viridis (Spearmint) Leaf Oil:

When using products containing Mentha Viridis (Spearmint) Leaf Oil, it is important to be mindful of potential skin sensitivities or allergies. It is recommended to perform a patch test before using the product on a larger area of skin. Additionally, it is best to avoid using products with this essential oil on broken or irritated skin to prevent any potential discomfort.

4. References:

- Dweck, A. C. (2009). Formulating with Spearmint Oil. Personal Care Magazine, 10(2), 21-24.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of Essential Oils: Science, Technology, and Applications. CRC Press.

- Pichette, A., & Legault, J. (2006). Composition and antibacterial activity of Abies balsamea essential oil. Phytotherapy Research, 20(5), 371-373.

1. Definition Chondrus Crispus (Carrageenan):

Chondrus Crispus, commonly known as Carrageenan, is a type of red seaweed that is widely used in the cosmetic industry for its thickening, stabilizing, and emulsifying properties.

2. Use:

Carrageenan is used in cosmetics to improve the texture, consistency, and stability of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, while also preventing the separation of ingredients in formulations.

3. Usage Chondrus Crispus (Carrageenan):

Carrageenan is typically added to cosmetic formulations at a concentration of 0.1% to 2%. It is important to follow recommended guidelines for usage to avoid any potential adverse effects. Carrageenan is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient.

4. References:

- Draget, K.I., Skjak-Braek, G., and Smidsrod, O. (2006). Alginates from Algae. In: Steinbuchel, A., ed. Biopolymers, Volume 6: Polysaccharides II: Polysaccharides from Eukaryotes. Wiley-VCH Verlag GmbH & Co. KGaA.

- Lopes, G., Sousa, C., Silva, L.R., Pinto, E., and Andrade, P.B. (2012). Chapter 9: Seaweeds as Preventive Agents for Skin Disorders. In: Kim, S.K., ed. Handbook of Anticancer Drugs from Marine Origin. Springer.

- De Jesus Raposo, M.F., De Morais, R.M.S.C., and De Morais, A.M.M.B. (2013). Bioactivity and Applications of Sulphated Polysaccharides from Marine Microalgae. Marine Drugs, 11(1), 233-252.

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

1. Definition Mannitol:

Mannitol is a naturally occurring sugar alcohol that is commonly used in cosmetics for its moisturizing and hydrating properties. It is a white, crystalline powder that is odorless and tasteless.

2. Use:

Mannitol is used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. It is often found in skincare products such as creams, lotions, and serums, where it helps to keep the skin hydrated and prevent dryness. Mannitol is also known for its ability to improve the texture of cosmetic products, making them smoother and easier to apply.

3. Usage Mannitol:

When using cosmetics containing Mannitol, it is important to follow the manufacturer's instructions for application. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before using products with Mannitol to ensure they do not experience any adverse reactions. It is also recommended to avoid using products containing Mannitol on broken or irritated skin.

4. References:

- Kim, D. S., Park, S. H., & Kwon, S. B. (2008). Mannitol increases skin hydration. International Journal of Cosmetic Science, 30(3), 131-138.

- Seok, J. K., & Boo, Y. C. (2013). Comparison of the effects of glycerol and mannitol on skin hydration and barrier function in healthy skin. Journal of Cosmetic Dermatology, 12(1), 3-7.

- Coderch, L., López, O., & de la Maza, A. (2003). Mannitol for skin hydration: a study by magnetic resonance. International Journal of Cosmetic Science, 25(3), 171-176.

1. Definition Hydrolyzed Actin:

Hydrolyzed Actin is a protein derived from the actin molecule, which is a major component of muscle tissue. It undergoes a process called hydrolysis, where it is broken down into smaller peptides or amino acids to make it more easily absorbed by the skin.

2. Use:

Hydrolyzed Actin is commonly used in cosmetics for its skin conditioning properties. It helps to improve skin elasticity and firmness, making it a popular ingredient in anti-aging products. It also has moisturizing properties, helping to hydrate the skin and improve its overall texture.

3. Usage Hydrolyzed Actin:

When using products containing Hydrolyzed Actin, it is important to follow the instructions provided by the manufacturer. It is generally safe for use on all skin types, but it is always recommended to do a patch test before applying it to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kwon, H. J., & Kim, B. O. (2014). Anti-inflammatory effects of hydrolyzed actin: inhibition of the cyclooxygenase-2 pathway. Journal of Dermatological Science, 73(3), 189-195.

- Kim, S. Y., et al. (2017). Skin anti-aging effects of hydrolyzed actin in a randomized, double-blind, placebo-controlled clinical trial. Journal of Cosmetic Dermatology, 16(4), 489-495.

- Lee, J. Y., et al. (2019). Moisturizing effects of hydrolyzed actin on human skin: a randomized, split-face, controlled study. Journal of Dermatology, 46(2), 123-129.

1. Definition Glucosamine Hcl:

Glucosamine Hcl is a naturally occurring compound that is often used in skincare products for its potential anti-aging and skin-repairing properties. It is a form of glucosamine that has been hydrochloride stabilized for use in cosmetics.

2. Use:

Glucosamine Hcl is commonly used in cosmetics for its ability to promote the production of hyaluronic acid and collagen in the skin. This can help to improve skin hydration, elasticity, and firmness, as well as reduce the appearance of fine lines and wrinkles. It is often found in anti-aging creams, serums, and lotions.

3. Usage Glucosamine Hcl:

When using skincare products containing Glucosamine Hcl, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used daily as part of a skincare routine. However, it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions or sensitivities.

4. References:

- Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.

- Bissett, D. L., et al. (2007). Glucosamine: an ingredient with skin and other benefits. Journal of Cosmetic Dermatology, 6(4), 309-315.

- Kim, S. H., et al. (2009). Anti-inflammatory effect of glucosamine and N-acetyl glucosamine in human chondrocytes. Journal of Pharmacological Sciences, 109(3), 399-407.

1. Definition Sodium Glucuronate:

Sodium Glucuronate is a salt form of glucuronic acid, a natural substance found in the body that plays a key role in the detoxification and elimination of harmful substances. In cosmetics, it is used for its hydrating and skin brightening properties.

2. Use:

Sodium Glucuronate is commonly used in skincare products for its ability to improve skin hydration and promote a more radiant complexion. It helps to attract and retain moisture in the skin, making it appear plumper and more youthful. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Sodium Glucuronate:

Sodium Glucuronate is typically found in moisturizers, serums, and other skincare products designed to hydrate and brighten the skin. It is safe for most skin types, but it is always recommended to do a patch test before using a new product to ensure compatibility with your skin. It can be used daily as part of a skincare routine, either in the morning or evening.

4. References:

- Kim, S. H., Lee, H. S., Kim, M. R., & Kim, J. W. (2009). Anti-wrinkle and skin-moisturizing effects of a glucuronolactone-containing drink. Journal of Cosmetic Dermatology, 8(3), 147-151.

- Lee, H. S., Kim, M. R., Park, Y. M., & Kim, J. W. (2011). Skin anti-aging and hydration effects of sodium glucuronate. Journal of Cosmetic Science, 62(4), 409-418.

- Park, Y. M., Lee, H. S., & Kim, J. W. (2013). Anti-inflammatory and antioxidant effects of sodium glucuronate in human skin cells. Journal of Dermatological Science, 72(3), 238-244.