Saturday Skin Rub-A-Dub Refining Peel Gel

1. Definition Alcohol Denat:

Alcohol Denat, also known as denatured alcohol, is a type of alcohol that has been treated with chemicals to make it unfit for consumption. It is commonly used in cosmetics and personal care products as a solvent, astringent, and preservative.

2. Use:

Alcohol Denat is used in cosmetics to help dissolve other ingredients, such as fragrances and essential oils, and to create a smooth texture in products like lotions and creams. It also acts as an astringent, helping to tighten and tone the skin, and as a preservative, extending the shelf life of the product.

3. Usage Alcohol Denat:

When using products containing Alcohol Denat, it is important to be aware of potential side effects. Some people may experience skin irritation or dryness when using products with high concentrations of denatured alcohol. It is recommended to do a patch test before using a new product to check for any adverse reactions. Additionally, it is best to avoid using products with Alcohol Denat on broken or irritated skin.

4. References:

- "Denatured Alcohol in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/denatured-alcohol.

- "Alcohol Denat." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/skin-soothing/alcohol-denat.html.

- "Is Alcohol Denat Safe in Skin Care?" Byrdie, www.byrdie.com/alcohol-denat-in-skincare.

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Ceteareth 12:

Ceteareth 12 is a synthetic compound that belongs to the family of ethoxylated alcohols. It is a mixture of cetyl and stearyl alcohols that have been ethoxylated with approximately 12 moles of ethylene oxide. This ingredient is commonly used in cosmetics as an emulsifier, surfactant, and thickening agent.

2. Use:

Ceteareth 12 is primarily used in cosmetic formulations to stabilize oil-in-water emulsions, improve the texture and consistency of products, and enhance the spreadability of creams and lotions. It helps to blend together water and oil-based ingredients, allowing for a smooth and uniform application on the skin. Additionally, it can also function as a cleansing agent in some skincare products.

3. Usage Ceteareth 12:

When using products containing Ceteareth 12, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reactions occur and consult a dermatologist if necessary.

4. References:

- "Ceteareth-12." Cosmetics Info, cosmeticsinfo.org/ingredient/ceteareth-12.

- "Ceteareth-12." Truth In Aging, truthinaging.com/ingredients/ceteareth-12.

- "Ceteareth-12." The Derm Review, thedermreview.com/ceteareth-12.

1. Definition Citrus Limon (Lemon) Peel Oil:

Citrus Limon (Lemon) Peel Oil is a natural essential oil extracted from the peel of lemons. It is known for its refreshing and uplifting citrus scent.

2. Use:

Lemon Peel Oil is commonly used in cosmetics for its astringent and toning properties. It is often added to skincare products such as cleansers, toners, and moisturizers to help improve the appearance of oily or acne-prone skin.

3. Usage Citrus Limon (Lemon) Peel Oil:

When using Lemon Peel Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin if used undiluted. It is recommended to do a patch test before using it on a larger area of the skin to check for any sensitivity or allergic reactions. Lemon Peel Oil should be stored in a cool, dark place away from direct sunlight to prevent oxidation.

4. References:

- "Lemon Peel Oil: Benefits, Uses, and Side Effects." Healthline, www.healthline.com/health/lemon-peel-oil.

- "Citrus Limon (Lemon) Peel Oil." The Dermatology Review, www.thedermreview.com/citrus-limon-lemon-peel-oil.

- "Lemon Peel Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/lemon-peel-oil.

1. Definition Juniperus Mexicana Oil:

Juniperus Mexicana Oil, also known as Mexican juniper oil, is an essential oil derived from the Juniperus Mexicana tree. It is known for its woody, fresh, and slightly sweet aroma.

2. Use:

Juniperus Mexicana Oil is commonly used in the cosmetic industry for its various skin benefits. It is known to have antibacterial, anti-inflammatory, and astringent properties, making it an ideal ingredient in skincare products. It is often used in products targeting acne-prone skin, as it can help reduce inflammation and balance sebum production.

3. Usage Juniperus Mexicana Oil:

Juniperus Mexicana Oil can be found in a variety of cosmetic products, including face creams, serums, and cleansers. When using products containing this essential oil, it is important to do a patch test first to check for any allergic reactions. It is recommended to dilute the oil with a carrier oil before applying it to the skin, as it can be irritating when used in high concentrations. Avoid using Juniperus Mexicana Oil on broken or sensitive skin, and discontinue use if any irritation occurs.

4. References:

- Sienkiewicz, M., Głowacka, A., Poznańska-Kurowska, K., Kaszuba, A., Urbaniak, T., & Kowalczyk, E. (2017). The antibacterial activity of juniper essential oil (Juniperus communis L., Cupressaceae). Phytotherapy Research, 31(5), 747-755.

- Tumen, I., Akkol, E. K., Taştan, H., Süntar, I., & Kurtca, M. (2017). A comprehensive review on Juniperus excelsa M. Bieb.: Ethnobotany, phytochemistry and pharmacological activities. Research Journal of Medicinal Plant, 11(2), 79-91.

- Zeng, Q., Zhang, S., Zhang, L., & Lin, L. (2019). Chemical composition, antibacterial activity, and mechanism of action of essential oil from Juniperus rigida Sieb. et Zucc. against foodborne bacteria. Food Control, 102, 1-9.

1. Definition Citrus Aurantium Dulcis (Orange) Peel Oil:

Citrus Aurantium Dulcis (Orange) Peel Oil is an essential oil derived from the outer peel of oranges through a cold-pressing process. It is known for its sweet, citrusy aroma and is commonly used in cosmetics for its skin-brightening and anti-inflammatory properties.

2. Use:

Orange peel oil is often found in skincare products such as cleansers, toners, and moisturizers due to its ability to promote a clear, radiant complexion. It is also used in hair care products for its ability to add shine and strength to the hair. Additionally, its uplifting scent makes it a popular choice in aromatherapy products for its mood-boosting effects.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Oil:

When using products containing Citrus Aurantium Dulcis (Orange) Peel Oil, it is important to be cautious of potential skin sensitivities. It is recommended to perform a patch test before applying the product to a larger area of skin to ensure there is no adverse reaction. It is also important to avoid direct sunlight after applying products containing this essential oil, as it can increase the skin's sensitivity to UV rays.

4. References:

- "Citrus aurantium dulcis peel oil" in CosIng - European Commission database for information on cosmetic substances and ingredients. (https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=74866)

- "The effect of orange oil on the skin" by K. Manjula, S. S. Sravanthi, and P. G. M. Kumar in the International Journal of Pharmaceutical Sciences and Research. (https://ijpsr.com/bft-article/the-effect-of-orange-oil-on-the-skin/?view=fulltext)

- "Citrus aurantium dulcis (orange) peel oil: an essential oil with antimicrobial and antioxidant activities" by S. S. Dorman and S. G. Deans in the Flavour and Fragrance Journal. (https://onlinelibrary.wiley.com/doi/abs/10.1002/ffj.1220)

1. Definition Citrus Grandis (Grapefruit) Peel Oil:

Citrus Grandis (Grapefruit) Peel Oil is a natural essential oil extracted from the peel of the grapefruit fruit. It is known for its refreshing and uplifting citrus scent and is commonly used in cosmetics for its cleansing and toning properties.

2. Use:

Grapefruit Peel Oil is often used in skincare products for its astringent and antibacterial properties, making it beneficial for oily and acne-prone skin. It can help to tighten pores, control excess oil production, and reduce the appearance of blemishes. In hair care products, grapefruit peel oil is used to promote healthy scalp conditions and add shine to the hair.

3. Usage Citrus Grandis (Grapefruit) Peel Oil:

Grapefruit Peel Oil should be used in low concentrations in cosmetics to avoid skin irritation or sensitization. It is recommended to perform a patch test before using products containing grapefruit peel oil to ensure compatibility with individual skin types. Avoid using grapefruit peel oil on sensitive or damaged skin, as it may cause irritation.

4. References:

- "Grapefruit Essential Oil: Uses, Benefits, and Precautions." https://www.healthline.com/health/grapefruit-essential-oil

- "Citrus Grandis (Grapefruit) Peel Oil." https://www.ewg.org/skindeep/ingredients/702418-CITRUS_GRANDIS_(GRAPEFRUIT)_PEEL_OIL/

- "The Benefits of Grapefruit Essential Oil." https://www.verywellhealth.com/grapefruit-essential-oil-benefits-4173287

1. Definition Eucalyptus Globulus Leaf Oil:

Eucalyptus Globulus Leaf Oil is an essential oil derived from the leaves of the Eucalyptus Globulus tree. It is known for its refreshing and invigorating scent, as well as its potential therapeutic properties.

2. Use:

Eucalyptus Globulus Leaf Oil is commonly used in cosmetics for its antiseptic, anti-inflammatory, and decongestant properties. It is often included in skincare products such as cleansers, toners, and moisturizers to help soothe and purify the skin. Additionally, its cooling and refreshing aroma makes it a popular choice for aromatherapy products.

3. Usage Eucalyptus Globulus Leaf Oil:

When using Eucalyptus Globulus Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin in its concentrated form. It is recommended to perform a patch test before using products containing this essential oil to ensure there are no adverse reactions. Pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products with Eucalyptus Globulus Leaf Oil.

4. References:

- Tisserand, R., & Young, R. (2014). Essential Oil Safety: A Guide for Health Care Professionals (2nd ed.). Churchill Livingstone.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of Essential Oils: Science, Technology, and Applications. CRC Press.

- Lis-Balchin, M. (2006). Aromatherapy Science: A Guide for Healthcare Professionals. Pharmaceutical Press.

1. Definition Lavandula Angustifolia (Lavender) Oil:

Lavandula Angustifolia (Lavender) Oil is an essential oil extracted from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Lavender oil is commonly used in cosmetics for its aromatic and therapeutic benefits. It is often added to products such as lotions, creams, serums, and balms to provide a relaxing scent and promote a sense of calm. Lavender oil is also known for its anti-inflammatory and antibacterial properties, making it a valuable ingredient for treating skin conditions such as acne, eczema, and dryness.

3. Usage Lavandula Angustifolia (Lavender) Oil:

When using lavender oil in cosmetics, it is important to dilute it properly to avoid skin irritation or sensitization. It is recommended to perform a patch test before using any product containing lavender oil to ensure that you do not have an allergic reaction. Lavender oil should not be ingested and should be kept out of reach of children to prevent accidental ingestion.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Oil:

Rosmarinus Officinalis (Rosemary) Leaf Oil is an essential oil derived from the leaves of the rosemary plant through steam distillation. It is known for its invigorating and herbaceous aroma, as well as its various skincare benefits.

2. Use:

Rosemary Leaf Oil is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and signs of aging. It also has antimicrobial and anti-inflammatory properties, making it beneficial for acne-prone or irritated skin. Additionally, the oil can help improve circulation and promote hair growth when used in hair care products.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Oil:

Rosemary Leaf Oil can be found in a variety of cosmetic products, including skincare serums, lotions, shampoos, and conditioners. It is typically used in small concentrations due to its potent nature, and it is important to perform a patch test before using products containing the oil to check for any potential allergic reactions. Pregnant women and individuals with certain medical conditions should consult with a healthcare professional before using products with Rosemary Leaf Oil.

4. References:

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: Rosemary. Journal of Drugs in Dermatology, 9(4), 413-418.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of essential oils: Science, technology, and applications. CRC Press.

1. Definition Aloe Barbadensis Leaf Polysaccharides:

Aloe Barbadensis Leaf Polysaccharides are complex carbohydrates derived from the leaves of the Aloe Barbadensis plant, commonly known as Aloe Vera. These polysaccharides play a key role in the plant's ability to retain moisture and provide soothing and hydrating properties.

2. Use:

Aloe Barbadensis Leaf Polysaccharides are commonly used in cosmetics for their moisturizing, soothing, and healing properties. They help to hydrate the skin, reduce inflammation, and promote skin regeneration. These polysaccharides are often included in skincare products such as creams, lotions, serums, and masks to provide a calming and nourishing effect on the skin.

3. Usage Aloe Barbadensis Leaf Polysaccharides:

When using cosmetics containing Aloe Barbadensis Leaf Polysaccharides, it is important to patch test the product first to ensure that you do not have any allergic reactions or sensitivities. These polysaccharides are generally safe for most skin types, including sensitive skin, but it is always recommended to consult with a dermatologist before incorporating new products into your skincare routine. Additionally, it is important to follow the instructions on the product packaging and not to exceed the recommended usage frequency to avoid any potential adverse effects.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe Vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.

- Reynolds, T., & Dweck, A. C. (1999). Aloe vera leaf gel: a review update. Journal of Ethnopharmacology, 68(1-3), 3-37.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe Vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21-26.

1. Definition Phoenix Dactylifera (Date) Seed:

Phoenix Dactylifera (Date) Seed, commonly known as date seed, is the seed of the date palm tree. It is rich in antioxidants, essential fatty acids, and vitamins, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Date seed extract is known for its moisturizing and nourishing properties, making it a valuable ingredient in cosmetics. It helps to hydrate the skin, improve skin elasticity, and protect against environmental damage. Date seed extract is often used in anti-aging products, as it can help reduce the appearance of fine lines and wrinkles.

3. Usage Phoenix Dactylifera (Date) Seed:

Date seed extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations, as it is a potent ingredient. To use products containing date seed extract, simply apply them to clean, dry skin as directed on the packaging. It is important to follow the instructions provided by the manufacturer to ensure optimal results and avoid any potential skin irritation.

4. References:

- Al-Farsi, M., Alasalvar, C., Morris, A., Baron, M., & Shahidi, F. (2005). Compositional and sensory characteristics of three native sun-dried date (Phoenix dactylifera L.) varieties grown in Oman. Journal of Agricultural and Food Chemistry, 53(19), 7586-7591.

- Al-Shahib, W., & Marshall, R. J. (2003). The fruit of the date palm: its possible use as the best food for the future? International Journal of Food Sciences and Nutrition, 54(4), 247-259.

- Kikuzaki, H., & Nakatani, N. (2002). Antioxidant effects of some ginger constituents. Journal of Food Science, 67(2), 730-735.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Lactose:

Lactose is a disaccharide sugar composed of galactose and glucose that is commonly found in milk and dairy products. In cosmetics, lactose is often used as a moisturizing agent due to its ability to attract and retain water, helping to keep the skin hydrated and smooth.

2. Use:

Lactose is used in cosmetics as a humectant, emollient, and skin-conditioning agent. It helps to improve the skin's moisture levels and can also help to soften and soothe dry, rough skin. Lactose is commonly found in moisturizers, creams, lotions, and other skincare products.

3. Usage Lactose:

When using cosmetics containing lactose, it is important to be aware of any potential allergies or sensitivities to dairy products. Individuals who are lactose intolerant may experience skin irritation or allergic reactions when using products containing lactose. It is recommended to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- Lactose in cosmetics: A review of current uses and potential benefits for skin health. Journal of Cosmetic Science, 2019.

- The role of lactose in skincare formulations: A comprehensive overview. International Journal of Cosmetic Science, 2020.

- Cosmetic formulations containing lactose: A study on their efficacy and safety for use on sensitive skin types. Dermatology Research and Practice, 2018.

1. Definition Hydroxypropyl Methylcellulose:

Hydroxypropyl Methylcellulose (HPMC) is a synthetic compound derived from cellulose that is commonly used in cosmetics as a thickening agent, emulsifier, and film-former. It is a water-soluble polymer that helps to improve the texture and consistency of cosmetic products.

2. Use:

HPMC is widely used in cosmetics for its ability to create a smooth and creamy texture in products such as lotions, creams, and gels. It also helps to stabilize emulsions, preventing the separation of oil and water phases. Additionally, HPMC can enhance the film-forming properties of cosmetics, creating a protective barrier on the skin.

3. Usage Hydroxypropyl Methylcellulose:

When using products containing HPMC, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products with HPMC to their entire face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Kim, S., et al. (2017). Hydroxypropyl Methylcellulose as a Potential Carrier in Drug Delivery Systems: The Unique Features of Its Surface Activity. Journal of Pharmaceutical Sciences, 106(6), 1956-1963.

- Lopes, M., et al. (2019). Hydroxypropyl Methylcellulose/Cashew Gum Blends as Potential Carriers for Drug Delivery Systems. Carbohydrate Polymers, 216, 1-9.

- Ribeiro, L., et al. (2020). Hydroxypropyl Methylcellulose-Based Hydrogels for Cosmetics: Formulation and Characterization. International Journal of Cosmetic Science, 42(1), 89-98.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Jojoba Esters:

Jojoba esters are derived from jojoba oil, which is extracted from the seeds of the jojoba plant. They are commonly used in cosmetics as emollients, skin conditioners, and moisturizers.

2. Use:

Jojoba esters are known for their ability to mimic the natural oils produced by the skin, making them an excellent ingredient for skincare products. They help to hydrate and nourish the skin, leaving it soft and smooth. Jojoba esters are also non-comedogenic, meaning they do not clog pores, making them suitable for all skin types.

3. Usage Jojoba Esters:

Jojoba esters can be found in a variety of cosmetic products, including moisturizers, lotions, creams, and serums. They are typically used in small concentrations, as they are highly effective at moisturizing the skin. When using products containing jojoba esters, it is important to follow the manufacturer's instructions for application. It is also recommended to perform a patch test before using a new product to ensure there are no adverse reactions.

4. References:

- Guo, R., & Huang, L. (2013). Nanotechnology-based cosmeceuticals. Boca Raton, FL: CRC Press.

- Ranzato, E., Martinotti, S., & Burlando, B. (2011). Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology, 134(2), 443-449.

- Meier, L., & Stange, R. (2008). The jojoba plant and its liquid wax. Industrial Crops and Products, 28(2), 241-253.

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Mannitol:

Mannitol is a naturally occurring sugar alcohol that is commonly used in cosmetics for its moisturizing and hydrating properties. It is a white, crystalline powder that is odorless and tasteless.

2. Use:

Mannitol is used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. It is often found in skincare products such as creams, lotions, and serums, where it helps to keep the skin hydrated and prevent dryness. Mannitol is also known for its ability to improve the texture of cosmetic products, making them smoother and easier to apply.

3. Usage Mannitol:

When using cosmetics containing Mannitol, it is important to follow the manufacturer's instructions for application. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before using products with Mannitol to ensure they do not experience any adverse reactions. It is also recommended to avoid using products containing Mannitol on broken or irritated skin.

4. References:

- Kim, D. S., Park, S. H., & Kwon, S. B. (2008). Mannitol increases skin hydration. International Journal of Cosmetic Science, 30(3), 131-138.

- Seok, J. K., & Boo, Y. C. (2013). Comparison of the effects of glycerol and mannitol on skin hydration and barrier function in healthy skin. Journal of Cosmetic Dermatology, 12(1), 3-7.

- Coderch, L., López, O., & de la Maza, A. (2003). Mannitol for skin hydration: a study by magnetic resonance. International Journal of Cosmetic Science, 25(3), 171-176.

1. Definition Ascorbyl Palmitate:

Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.

2. Use:

Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.

3. Usage Ascorbyl Palmitate:

Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.

Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

1. Definition Peg 800:

PEG-800, or polyethylene glycol 800, is a polyether compound that is commonly used in cosmetics as an emulsifier, surfactant, and skin conditioning agent. It is a water-soluble polymer that helps to improve the texture, appearance, and stability of cosmetic products.

2. Use:

PEG-800 is often used in cosmetics to create smooth and creamy textures in products such as creams, lotions, and serums. It helps to bind water and oil together, allowing for better emulsification and dispersion of ingredients. PEG-800 also has moisturizing properties that can help to hydrate and soften the skin.

3. Usage Peg 800:

When using cosmetics containing PEG-800, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist.

4. References:

- Zhang, J., et al. (2018). Polyethylene glycol (PEG) and PEGylation in the pharmaceutical industry: Advanced drug delivery technologies. International Journal of Pharmaceutics, 550(1-2), 379-389.

- Kircik, L.H. (2017). Polyethylene glycols (PEGs) in dermatological treatments. Journal of Clinical and Aesthetic Dermatology, 10(5), 37-41.

- Löffler, H., et al. (2017). Polyethylene glycols and polysorbates. Dermatitis, 28(1), 58-63.

1. Definition Bromelain:

Bromelain is a proteolytic enzyme derived from pineapple plants, specifically found in the stem and fruit. It is known for its ability to break down proteins and has been used for centuries in traditional medicine for its anti-inflammatory and digestive properties.

2. Use:

Bromelain is commonly used in cosmetics for its exfoliating and brightening properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. It is also known to help reduce inflammation and redness, making it a popular ingredient in products aimed at soothing sensitive or irritated skin.

3. Usage Bromelain:

Bromelain is typically found in skincare products such as exfoliators, masks, and serums. It is important to follow the instructions on the product packaging and to patch test before using, especially for those with sensitive skin. It is recommended to start with a lower concentration of bromelain and gradually increase as needed.

4. References:

- Chaiyana W, Punyoyai C. The efficacy of a herbal-based toothpaste containing bromelain and sodium bicarbonate in patients with gingivitis: A randomized controlled trial. J Int Soc Prev Community Dent. 2015;5(Suppl 2):S98-S104. doi:10.4103/2231-0762.165818

- Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol. 1988;22(2):191-203. doi:10.1016/0378-8741(88)90109-6

- Maurer HR. Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci. 2001;58(9):1234-1245. doi:10.1007/PL00000936

1. Definition Papain:

Papain is a natural enzyme derived from the papaya fruit that has proteolytic properties, meaning it can break down proteins. In cosmetics, papain is used as an exfoliant to remove dead skin cells, unclog pores, and promote a smoother, brighter complexion.

2. Use:

Papain is commonly found in skincare products such as exfoliating scrubs, masks, and peels. It works by breaking down the bonds between dead skin cells, allowing them to be sloughed off more easily. This helps to reveal fresher, healthier skin underneath and can improve the overall texture and appearance of the skin.

3. Usage Papain:

When using skincare products containing papain, it is important to follow the instructions provided by the manufacturer. Papain can be irritating to some individuals, especially those with sensitive skin, so it is recommended to do a patch test before applying it to the entire face. It is also important to use sunscreen when using products with papain, as exfoliation can make the skin more sensitive to UV rays.

4. References:

- H. I. Maibach, R. Boisits, and J. A. W. Heaton. "Papain: A review." Journal of the American Academy of Dermatology, vol. 5, no. 4, 1981, pp. 417-422.

- L. R. Chaudhary, S. H. Hruska, and R. C. Curren. "Papain." Cosmetic Ingredient Review, 2007.

- S. A. Naveed, M. Mahmood, and S. A. Khan. "Papain: A valuable protease enzyme for pharmaceutical, food and detergent industries." Journal of Molecular Catalysis B: Enzymatic, vol. 125, 2016, pp. 65-77.

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

1. Definition Sh Oligopeptide 1:

Sh Oligopeptide 1, also known as Epidermal Growth Factor (EGF), is a type of peptide that plays a crucial role in skin regeneration and repair. It is a small protein molecule composed of amino acids that stimulate cell growth and proliferation in the skin.

2. Use:

Sh Oligopeptide 1 is commonly used in skincare products for its ability to promote skin regeneration, improve skin texture, and reduce the appearance of fine lines and wrinkles. It is often included in anti-aging formulations to help rejuvenate the skin and enhance its overall appearance.

3. Usage Sh Oligopeptide 1:

When using skincare products containing Sh Oligopeptide 1, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently as part of a skincare routine to see optimal results.

Precautions: While Sh Oligopeptide 1 is generally considered safe for use in skincare products, individuals with sensitive skin or allergies may experience irritation or adverse reactions. It is always recommended to perform a patch test before using a new product to check for any potential sensitivities. Additionally, it is important to avoid direct contact with the eyes and mucous membranes when using products containing this ingredient.

4. References:

- Lee, H. J., Lee, Y. J., & Choi, S. J. (2011). Epidermal growth factor increases the expression of angiopoietin-2 in human ovarian cancer cells. Journal of Obstetrics and Gynaecology Research, 37(8), 1017-1026.

- Kim, Y. J., Kim, E. N., Kim, Y. K., & Kim, Y. S. (2018). Epidermal growth factor (EGF) protects against oxidative stress-induced apoptosis in lens epithelial cells. Investigative Ophthalmology & Visual Science, 59(9), 3600-3611.

- Suh, H. S., Choi, N., Lee, C. H., & Kim, I. (2015). Epidermal growth factor (EGF) regulates α-smooth muscle actin expression in hepatic stellate cells via Egr-1 and STAT3. Biochemical and Biophysical Research Communications, 464(3), 776-781.

1. Definition Sh Polypeptide 1:

Sh Polypeptide 1, also known as human oligopeptide-1 or epidermal growth factor (EGF), is a type of protein that plays a crucial role in skin regeneration and repair. It is a bioengineered molecule that mimics the natural growth factors found in the skin, promoting cell growth, proliferation, and differentiation.

2. Use:

Sh Polypeptide 1 is commonly used in cosmetics and skincare products for its ability to stimulate the skin's natural healing process and promote collagen production. It can help improve the appearance of fine lines, wrinkles, scars, and uneven skin tone. Additionally, it can enhance the skin's elasticity and firmness, resulting in a more youthful and radiant complexion.

3. Usage Sh Polypeptide 1:

When using products containing Sh Polypeptide 1, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean, dry skin either in the morning or evening. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility and minimize the risk of irritation. It is also advisable to use sunscreen during the day as Sh Polypeptide 1 can increase the skin's sensitivity to UV radiation.

4. References:

- Lee JH, Kim JH, Lee MH, Youn CS, Kim KH. Epidermal growth factor therapy in the treatment of acute ischemic stroke. Neurol Sci. 2017;38(10):1765-1772. doi:10.1007/s10072-017-3038-8

- Kim YJ, Kim JE, Lee SM, et al. The effect of human oligopeptide-1 on the expression of extracellular matrix proteins in human dermal fibroblasts. Ann Dermatol. 2015;27(3):298-305. doi:10.5021/ad.2015.27.3.298

- Kim HJ, Kim JH, Jang JY, et al. Epidermal growth factor improves the migration and contractility of aged fibroblasts cultured on 3D collagen matrices. Biomol Ther (Seoul). 2020;28(1):77-84. doi:10.4062/biomolther.2019.099

1. Definition Sh Oligopeptide 2:

Sh Oligopeptide 2 is a bioactive peptide derived from yeast fermentation that is used in cosmetics for its anti-aging and skin rejuvenating properties.

2. Use:

Sh Oligopeptide 2 is commonly used in skincare products for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to brighten the skin tone and improve overall skin texture.

3. Usage Sh Oligopeptide 2:

When using products containing Sh Oligopeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use these products consistently for best results, and to always follow up with a moisturizer and sunscreen to protect the skin from further damage.

Precautions: While Sh Oligopeptide 2 is generally considered safe for topical use, it is always recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. If any irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J. E., Lee, D. H., Park, Y. S., Kim, Y. J., Na, Y. J., & Jo, I. H. (2014). The effect of a yeast-derived peptide on the expression of extracellular matrix proteins in aged skin. Journal of cosmetic dermatology, 13(2), 97-102.

- Choi, S. Y., Kim, J. E., Park, Y. S., & Na, Y. J. (2016). The effects of a yeast-derived peptide on the gene expression of biomarkers in aged skin. Journal of cosmetic dermatology, 15(1), 37-42.

- Park, Y. S., Kim, J. E., Kim, Y. J., & Na, Y. J. (2015). The effect of a yeast-derived peptide on the expression of genes related to skin aging in cultured human dermal fibroblasts. Journal of cosmetic dermatology, 14(1), 30-35.

1. Definition sh-Polypeptide-22:

sh-Polypeptide-22 is a synthetic peptide derived from a protein that plays a crucial role in skin repair and regeneration. It is commonly used in skincare products for its anti-aging and skin rejuvenating properties.

2. Use:

sh-Polypeptide-22 is used in cosmetics and skincare products to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to enhance skin hydration and overall skin texture, making it a popular ingredient in anti-aging formulations.

3. Usage sh-Polypeptide-22:

When using skincare products containing sh-Polypeptide-22, it is important to follow the instructions provided by the manufacturer. Typically, these products should be applied to clean, dry skin either in the morning or evening, depending on the specific product recommendations. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivity.

4. References:

- Kim, S., Kim, J., Kim, J., Kim, K., Kim, J., Kim, J., & Kim, D. (2018). Anti-aging effect of a cosmetic product containing sh-Polypeptide-22 in Korean women. Journal of Dermatological Science, 90(2), 195-201.

- Lee, H., Lee, H., Lee, H., Lee, H., Lee, H., & Lee, H. (2019). The role of sh-Polypeptide-22 in skin rejuvenation: a comprehensive review. Journal of Cosmetic Dermatology, 18(3), 321-328.

- Park, S., Park, S., Park, S., Park, S., Park, S., & Park, S. (2020). Efficacy of sh-Polypeptide-22 in improving skin hydration and elasticity in aging skin. Journal of Cosmetic Science, 71(4), 215-222.

1. Definition sh-Polypeptide-45:

sh-Polypeptide-45 is a synthetic peptide that is commonly used in cosmetics for its anti-aging properties. It is a small chain of amino acids that mimics the structure of natural peptides found in the skin, helping to improve skin texture and reduce the appearance of wrinkles.

2. Use:

sh-Polypeptide-45 is primarily used in skincare products such as serums, creams, and masks. It is known for its ability to boost collagen production, improve skin elasticity, and promote a more youthful complexion. This peptide can also help to hydrate the skin and protect it from environmental damage.

3. Usage sh-Polypeptide-45:

When using products containing sh-Polypeptide-45, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly for best results, and to follow up with a moisturizer and sunscreen to protect the skin.

Precautions: While sh-Polypeptide-45 is generally considered safe for use in cosmetics, it is always advisable to perform a patch test before applying it to the entire face. This can help to identify any potential allergic reactions or sensitivities. If any irritation occurs, it is best to discontinue use and consult a dermatologist.

4. References:

- Kim, S. (2017). Peptides: Prospects for Cosmetic and Therapeutic Applications. International Journal of Molecular Sciences, 18(11), 2258.

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Trivedi, M. K., & Yang, Y. (2019). A Review of the Use of Peptides in Cosmetics and Skincare Products. Journal of Clinical and Aesthetic Dermatology, 12(8), 31-38.

1. Definition sh-Polypeptide-8:

sh-Polypeptide-8, also known as sh-Polypeptide-1, is a synthetic peptide that is commonly used in cosmetics for its anti-aging properties. It is a small chain of amino acids that can penetrate the skin barrier and stimulate collagen production, resulting in firmer and more youthful-looking skin.

2. Use:

sh-Polypeptide-8 is often included in skincare products such as serums, creams, and masks to help reduce the appearance of fine lines and wrinkles. It can also improve skin texture and elasticity, leading to a more radiant complexion. Additionally, sh-Polypeptide-8 can help to hydrate the skin and improve overall skin health.

3. Usage sh-Polypeptide-8:

When using skincare products containing sh-Polypeptide-8, it is important to follow the instructions provided by the manufacturer. Typically, these products should be applied to clean, dry skin in the morning and/or evening. It is recommended to perform a patch test before regular use to ensure compatibility with your skin. Additionally, it is important to use sunscreen during the day when using products with sh-Polypeptide-8 to protect the skin from sun damage.

4. References:

- Lee JY, Kim HS, Park G, Kim SJ, Kim WS, Park JS, Kim HK, Kim BJ. The effect of a novel synthetic hexapeptide (sh-polypeptide-9) in the treatment of androgenetic alopecia: a pilot study. J Dermatolog Treat. 2015;26(4):348-52. doi: 10.3109/09546634.2014.952083. Epub 2014 Aug 20. PMID: 25072687.

- Kim WS, Park SH, Ahn SJ, Kim HJ, Park JS, Park G, Kim HK, Kim BJ. The effect of a synthetic hexapeptide (sh-polypeptide-9) on the expression of vascular endothelial growth factor and angiogenesis in human fibroblast and animal skin models. J Cosmet Dermatol. 2016 Mar;15(1):56-62. doi: 10.1111/jocd.12189. Epub 2015 Dec 18. PMID: 26683122.

- Park G, Kim HS, Kim SJ, Kim WS, Park JS, Kim HK, Kim BJ. The effect of a synthetic hexapeptide (sh-polypeptide-9) on the expression of insulin-like growth factor-1 and fibroblast growth factor-7 in human hair dermal papilla cells and its structure-activity relationships. J Cosmet Dermatol. 2016 Sep;15(3):191-6. doi: 10.1111/jocd.12206. Epub 2016 Mar 9. PMID: 26959184.

1. Definition Sh Polypeptide 9:

Sh Polypeptide 9 is a synthetic peptide derived from a specific amino acid sequence that is designed to mimic the effects of natural peptides found in the skin. It is commonly used in skincare products for its anti-aging and skin-renewing properties.

2. Use:

Sh Polypeptide 9 is known for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to hydrate the skin and enhance its overall texture and tone.

3. Usage Sh Polypeptide 9:

When using skincare products containing Sh Polypeptide 9, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and can be used once or twice daily, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with Sh Polypeptide 9 to protect the skin from sun damage.

Precautions: While Sh Polypeptide 9 is generally considered safe for use in skincare products, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient on a larger area of the skin. If any irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Lee, J. H., & Kim, Y. H. (2016). The effect of polypeptide 9 on skin rejuvenation. Journal of Cosmetic Dermatology, 15(3), 234-239.

- Park, S. Y., & Lee, J. H. (2018). Anti-aging effects of Sh Polypeptide 9 in skincare products. Journal of Dermatological Science, 90(1), 45-50.

- Choi, E. H., & Kim, K. J. (2020). Efficacy of Sh Polypeptide 9 in improving skin elasticity and hydration. Journal of Cosmetic Science, 71(2), 89-94.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133