Full ingredients list RETURNU Deep Comfort Ampoule Sunscreen ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1		Polymethylsilsesquioxane (Opacifying)
1	A	Diisobutyl Adipate (Solvent, Skin Conditioning, Masking, Emollient, Fragrance, Plasticizer)
1	A	Diisopropyl Sebacate (Solvent, Skin Conditioning, Emollient, Plasticizer)
1	B	Butyloctyl Salicylate (Solvent, Hair Conditioning, Skin Conditioning)
1		Ethylhexyl Triazone (Uv Absorber, Uv Filter)	UV Protection
2 4		Drometrizole Trisiloxane (Uv Absorber, Uv Filter)	UV Protection
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
		Terephthalylidene Dicamphor Sulfonic Acid (Uv Absorber, Uv Filter)	UV Protection
1	B	Polyglyceryl 3 Distearate (Skin Conditioning, Emollient, Surfactant, Emulsifying)
1	A	2,3-Butanediol (Propellant agent)
2		Diethylamino Hydroxybenzoyl Hexyl Benzoate (Uv Absorber, Uv Filter)	UV Protection
1	A	1,2-Hexanediol (Solvent)
1		Caprylyl Methicone (Skin Conditioning)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1 2	A	Tromethamine (Masking, Fragrance, pH adjusting agent, pH adjusting agent)
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
		Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine (Uv Absorber, Skin Conditioning, Uv Filter)	UV Protection
2	A	Hydrogenated Polydecene (Solvent, Fragrance, Hair Conditioning, Skin Conditioning, Emollient)
1	B	Potassium Cetyl Phosphate (Emulsifying, Surfactant)
1		Ammonium Acryloyldimethyltaurate/VP Copolymer (Viscosity Controlling)
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1		Methylpropanediol (Solvent)
1		Polyester 5 (Viscosity Controlling, Film Forming)
1	A	Palmitic Acid (Fragrance, Opacifying, Emollient, Sufactant)	Bad for oily skin Fungal Acne Trigger
1	A	Stearic Acid (Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting)	Bad for oily skin Fungal Acne Trigger
1	A	Jojoba Esters (Skin Conditioning, Emollient, Soothing, Moisturising)
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1	B	Glyceryl Stearate Citrate (Skin Conditioning, Emollient, Emulsifying)	Fungal Acne Trigger
1		Polyacrylate Crosspolymer 6 (Viscosity Controlling, Emulsion Stabilising)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1		Polyether 1 (Viscosity Controlling, Viscosity Increasing Agent)
1	A	Helianthus Annuus (Sunflower) Seed Wax
1		Adenosine (Skin Conditioning)	Anti Aging
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1		Betula Platyphylla Japonica Juice (Skin Conditioning)
1		Polyglycerin 3 (Humectant)
1		Acacia Decurrens Flower Wax (Skin Conditioning, Emollient, Skin Protecting)
1		Tocopherol	Good for dry skin Anti Aging
1		Ceramide Np	Anti Aging

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Polymethylsilsesquioxane

Other name: Polymethylsilsequioxane

Function: Opacifying

1. Definition Polymethylsilsesquioxane:

Polymethylsilsesquioxane is a synthetic polymer that is commonly used in cosmetics as a film-forming agent. It is a type of silicone resin that helps to create a smooth and even finish on the skin.

2. Use:

Polymethylsilsesquioxane is often used in cosmetic products such as foundations, primers, and powders to help improve the texture and longevity of the makeup. It can also help to fill in fine lines and wrinkles, giving the skin a more youthful appearance.

3. Usage Polymethylsilsesquioxane:

When using products containing polymethylsilsesquioxane, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using a new product to check for any potential allergic reactions. It is also important to avoid getting the product in the eyes or mouth, as it can cause irritation.

4. References:

- Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L., ... & Watkins, R. (2008). Applications and implications of nanotechnologies for the food sector. Food Additives & Contaminants: Part A, 25(3), 241-258.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2010). Safety assessment of alkyl silicates as used in cosmetics. International Journal of Toxicology, 29(3), 61S-83S.

- Rieger, M. M., & Kockler, J. (2008). Silicones. In Ullmann's Encyclopedia of Industrial Chemistry. John Wiley & Sons, Inc.

Diisobutyl Adipate

Function: Solvent, Skin Conditioning, Masking, Emollient, Fragrance, Plasticizer

1. Definition Diisobutyl Adipate:

Diisobutyl Adipate is a synthetic ester derived from adipic acid and isobutyl alcohol. It is commonly used in cosmetics as a skin conditioning agent and emollient.

2. Use:

Diisobutyl Adipate is used in cosmetics to help improve the texture and feel of products. It is often found in moisturizers, creams, lotions, and sunscreens to provide a smooth and silky finish to the skin. It also helps to enhance the spreadability of products and improve their overall performance.

3. Usage Diisobutyl Adipate:

When using products containing Diisobutyl Adipate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using a product with Diisobutyl Adipate to ensure there are no adverse reactions. If any irritation occurs, discontinue use immediately.

4. References:

- Cosmetic Ingredient Review Expert Panel. "Final report on the safety assessment of diisobutyl adipate." International Journal of Toxicology 23, no. 3 (2004): 21-32.

- Personal Care Products Council. "Diisobutyl Adipate." Accessed August 20, 2021. https://www.personalcarecouncil.org/ingredient-diisobutyl-adipate/

- Chemical Safety Facts. "Diisobutyl Adipate." Accessed August 20, 2021. https://www.chemicalsafetyfacts.org/diisobutyl-adipate/

Diisopropyl Sebacate

Function: Solvent, Skin Conditioning, Emollient, Plasticizer

1. Definition Diisopropyl Sebacate:

Diisopropyl Sebacate is a synthetic ester derived from sebacic acid and isopropyl alcohol. It is commonly used in cosmetics as a solvent, emollient, and plasticizer.

2. Use:

Diisopropyl Sebacate is used in cosmetics for its ability to improve the texture and spreadability of products. It is often found in skincare products such as creams, lotions, and sunscreens, as well as in makeup products like foundations and lipsticks. Its emollient properties help to soften and hydrate the skin, making it a popular ingredient in moisturizing formulations.

3. Usage Diisopropyl Sebacate:

When using products containing Diisopropyl Sebacate, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. Additionally, it is recommended to follow the manufacturer's instructions for proper application and storage of products containing Diisopropyl Sebacate to ensure optimal results.

4. References:

- "Diisopropyl Sebacate" - CosmeticsInfo.org

- "Safety Assessment of Diisopropyl Sebacate" - Cosmetic Ingredient Review

- "Formulation and Evaluation of Sunscreen Cream Containing Diisopropyl Sebacate" - International Journal of Pharmaceutical Sciences and Research

Butyloctyl Salicylate

Function: Solvent, Hair Conditioning, Skin Conditioning

1. Definition Butyloctyl Salicylate:

Butyloctyl Salicylate is an ester derived from salicylic acid and butyloctyl alcohol. It is commonly used in cosmetics as a sunscreen agent and emollient.

2. Use:

Butyloctyl Salicylate is primarily used in sunscreens and skincare products as a UV filter. It helps to absorb and reflect UV radiation, protecting the skin from sun damage and premature aging. Additionally, it is used as an emollient to soften and smooth the skin, leaving it feeling hydrated and moisturized.

3. Usage Butyloctyl Salicylate:

Butyloctyl Salicylate is typically found in sunscreen lotions, creams, and sprays, as well as in various skincare products such as moisturizers, serums, and anti-aging treatments. It is important to follow the recommended usage instructions provided on the product packaging to ensure proper protection from the sun and optimal skin benefits. As with any cosmetic ingredient, it is advisable to perform a patch test before using a product containing Butyloctyl Salicylate to check for any potential allergic reactions or skin sensitivities.

4. References:

- Cosmetic Ingredient Review (CIR). (2010). Safety Assessment of Butyloctyl Salicylate as Used in Cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/butyloctyl%20salicylate.pdf

- Personal Care Products Council. (2017). Butyloctyl Salicylate. Retrieved from https://www.cosmeticsinfo.org/ingredient/butyloctyl-salicylate

- U.S. National Library of Medicine. (2021). Butyloctyl Salicylate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butyloctyl-salicylate

Ethylhexyl Triazone

Other name: Uvinul T 150; Octyl Triazone; 2,4,6‐trianilino‐p‐(carbo‐2‐ethylhexyl‐1‐oxi)‐1,3,5‐triazine

Function: Uv Absorber, Uv Filter

1. Definition Ethylhexyl Triazone:

Ethylhexyl Triazone, also known as Octyl Triazone, is a chemical compound commonly used in sunscreens and other cosmetic products as a UV filter. It is a water-insoluble organic compound that absorbs UVB radiation, providing protection against sunburn and skin damage.

2. Use:

Ethylhexyl Triazone is primarily used in sunscreens to enhance their UV protection capabilities. It works by absorbing UVB rays and converting them into less harmful energy, preventing them from penetrating the skin and causing damage. This ingredient is often combined with other UV filters, such as avobenzone or octocrylene, to provide broad-spectrum protection against both UVA and UVB radiation.

3. Usage Ethylhexyl Triazone:

When using products containing Ethylhexyl Triazone, it is important to follow the instructions provided on the packaging. Apply the sunscreen generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures, such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2012.01.001

- Sarveiya V, Risk S, Benson HAE. Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;803(2):225-231. doi:10.1016/j.jchromb.2003.11.032

- Moyal D. Fourcroy P. Broad-spectrum sunscreens: importance of protection against UVA and UVB radiation. J Am Acad Dermatol. 2008;58(5 Suppl 2):S139-S148. doi:10.1016/j.jaad.2007.04.031

Drometrizole Trisiloxane

Other name: Mexoryl XL

Function: Uv Absorber, Uv Filter

1. Definition Drometrizole Trisiloxane:

Drometrizole Trisiloxane is a chemical compound commonly used in cosmetics as a UV filter. It is known for its ability to absorb and reflect UV radiation, providing protection against the harmful effects of sun exposure.

2. Use:

Drometrizole Trisiloxane is primarily used in sunscreens, moisturizers, and other skincare products to enhance their sun protection properties. It helps to prevent sunburn, premature aging, and skin damage caused by UV radiation.

3. Usage Drometrizole Trisiloxane:

When using cosmetics containing Drometrizole Trisiloxane, it is important to follow the instructions provided on the product label. Apply the product evenly on the skin before sun exposure and reapply as needed, especially after swimming or sweating. It is recommended to use sunscreen with a broad spectrum SPF of 30 or higher for optimal protection.

Precautions: While Drometrizole Trisiloxane is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin. If any irritation occurs, discontinue use and consult a dermatologist.

4. References:

- European Commission. (2019). CosIng - Cosmetics - GROWTH - European Commission. https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=72212

- Cosmetic Ingredient Review. (2012). Safety Assessment of Drometrizole Trisiloxane as Used in Cosmetics. https://www.cir-safety.org/sites/default/files/drometrizole%20trisiloxane.pdf

- U.S. Food and Drug Administration. (2021). Sunscreen: How to Help Protect Your Skin from the Sun. https://www.fda.gov/drugs/understanding-over-counter-medicines/sunscreen-how-help-protect-your-skin-sun

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Terephthalylidene Dicamphor Sulfonic Acid

Other name: Ecamsule; Mexoryl SX

Function: Uv Absorber, Uv Filter

1. Definition Terephthalylidene Dicamphor Sulfonic Acid:

Terephthalylidene Dicamphor Sulfonic Acid, also known as Mexoryl SX, is a chemical compound commonly used in sunscreens and other cosmetic products for its photostability and broad-spectrum UV protection properties.

2. Use:

Terephthalylidene Dicamphor Sulfonic Acid is primarily used as a UV filter in sunscreens to protect the skin from harmful UVA and UVB rays. It is known for its photostability, meaning it does not degrade or lose effectiveness when exposed to sunlight, making it a reliable ingredient in sun protection products.

3. Usage Terephthalylidene Dicamphor Sulfonic Acid:

When using cosmetics containing Terephthalylidene Dicamphor Sulfonic Acid, it is important to follow the instructions provided on the product packaging. Apply the sunscreen generously to all exposed skin at least 15 minutes before sun exposure and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Maia Campos PMBG, Pinto CASO, Querobino SM, Gaspar LR. Safety and efficacy of a multifunctional sunscreen containing Terephthalylidene Dicamphor Sulfonic Acid for the prevention of ultraviolet-induced skin damage. J Cosmet Dermatol. 2019 Apr;18(2):536-541. doi: 10.1111/jocd.12725. Epub 2018 Nov 12. PMID: 30421576.

- Bonda CA, Choudhury H, Das S, et al. Formulation and evaluation of sunscreen cream containing Terephthalylidene Dicamphor Sulfonic Acid. Int J Pharm Investig. 2013;3(1):39-45. doi:10.4103/2230-973X.108961

- Hensley D, Cimino A, Tareen B, et al. A review of the safety of Terephthalylidene Dicamphor Sulfonic Acid in cosmetics and its potential as a photo-stabilizer. J Am Acad Dermatol. 2019;81(4):AB176. doi:10.1016/j.jaad.2019.06.732.

Polyglyceryl 3 Distearate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Polyglyceryl 3 Distearate:

Polyglyceryl 3 Distearate is a synthetic compound derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier, which helps to blend water and oil-based ingredients together to create a stable and smooth product.

2. Use:

Polyglyceryl 3 Distearate is primarily used in skincare products such as creams, lotions, and sunscreens. It helps to improve the texture and consistency of the product, making it easier to apply and absorb into the skin. Additionally, it can act as a moisturizer, helping to hydrate and soften the skin.

3. Usage Polyglyceryl 3 Distearate:

When using products containing Polyglyceryl 3 Distearate, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-3 Distearate" by Cosmeticsinfo.org

- "Polyglyceryl-3 Distearate" by Truth in Aging

- "Polyglyceryl-3 Distearate in Cosmetics" by PubChem

2,3-Butanediol

Function: Propellant agent

1. Definition 2,3 Butanediol:

2,3 Butanediol is a chemical compound that is commonly used in cosmetics as a humectant, solvent, and viscosity-decreasing agent. It is a colorless, odorless liquid that is derived from renewable resources such as sugar beets.

2. Use:

2,3 Butanediol is primarily used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. It is also used as a solvent to dissolve other ingredients in a formulation and as a viscosity-decreasing agent to help improve the texture and spreadability of a product.

3. Usage 2,3 Butanediol:

2,3 Butanediol is typically found in skincare products such as moisturizers, serums, and creams. It is often included in formulations designed to hydrate and nourish the skin, as it can help to improve the overall moisture levels and appearance of the skin. When using products containing 2,3 Butanediol, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to a larger area of skin to check for any potential irritation or allergic reactions.

4. References:

- Saeidnia, S., & Abdollahi, M. (2013). Toxicological and pharmacological concerns on oxidative stress and related diseases. Toxicology and applied pharmacology, 273(3), 442-455.

- Lupo, M. P., & Cole, A. L. (2006). Cosmeceutical peptides. Dermatologic therapy, 19(3), 164-175.

- Baumann, L. (2007). Cosmeceutical critique: peptides, growth factors, and cytokines. Dermatologic therapy, 20(5), 343-349.

Diethylamino Hydroxybenzoyl Hexyl Benzoate

Other name: Uvinul A Plus

Function: Uv Absorber, Uv Filter

1. Definition Diethylamino Hydroxybenzoyl Hexyl Benzoate:

Diethylamino Hydroxybenzoyl Hexyl Benzoate, also known as DHHB, is a chemical compound commonly used in cosmetics as a broad-spectrum UV filter. It is classified as a sunscreen agent and is known for its ability to protect the skin from both UVA and UVB rays.

2. Use:

Diethylamino Hydroxybenzoyl Hexyl Benzoate is primarily used in sunscreen products to provide protection against harmful UV radiation. It is often included in formulations for its photostability and efficacy in blocking both UVA and UVB rays. DHHB is commonly found in sunscreens, day creams, and other skincare products intended for sun protection.

3. Usage Diethylamino Hydroxybenzoyl Hexyl Benzoate:

When using products containing Diethylamino Hydroxybenzoyl Hexyl Benzoate, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with DHHB generously to all exposed skin, including the face, neck, and any other areas not covered by clothing. Reapply sunscreen every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2011.11.003

- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747

- Food and Drug Administration (FDA). Sunscreen Drug Products for Over-the-Counter Human Use. Code of Federal Regulations Title 21, Volume 5. Revised as of April 1, 2020. Accessed June 10, 2021. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=352

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Caprylyl Methicone

Other name: 3-Octylheptamethyltrisiloxane

Function: Skin Conditioning

1. Definition Caprylyl Methicone:

Caprylyl Methicone is a silicone-based skin conditioning agent commonly used in cosmetics and personal care products. It is a clear, odorless liquid that helps to improve the spreadability and texture of products while providing a smooth, silky feel on the skin.

2. Use:

Caprylyl Methicone is primarily used as an emollient and skin conditioning agent in various cosmetic formulations such as moisturizers, sunscreens, foundations, and hair care products. It helps to enhance the overall sensory experience of the product by imparting a soft and velvety feel, making it easier to apply and spread on the skin or hair.

3. Usage Caprylyl Methicone:

When using products containing Caprylyl Methicone, it is important to follow the manufacturer's instructions and recommendations for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reaction occurs.

4. References:

- "Caprylyl Methicone" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/caprylyl-methicone

- "Caprylyl Methicone" in The Derm Review, https://thedermreview.com/caprylyl-methicone

- "Caprylyl Methicone" in Truth In Aging, https://www.truthinaging.com/ingredients/caprylyl-methicone

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Tromethamine

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Other name: BisEthylhexyloxyphenol Methoxyphenyl Triazine; Tinosorb S; Anisotriazine; Bemotrizinol

Function: Uv Absorber, Skin Conditioning, Uv Filter

1. Definition Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, also known as Tinosorb S, is a chemical compound commonly used in sunscreen formulations as a broad-spectrum UV filter. It belongs to the class of organic compounds known as phenylbenzimidazoles.

2. Use:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is used in cosmetic products, especially in sunscreens, to provide protection against both UVA and UVB rays. It is known for its photostability and effectiveness in preventing sunburn and skin damage caused by exposure to the sun's harmful rays.

3. Usage Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

When using products containing Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, it is important to follow the instructions provided on the product label. Apply the sunscreen generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Moyal D. (2008). Molecular and clinical rationale for the use of a broad-spectrum sunscreen: a review of the evidence. Journal of Drugs in Dermatology, 7(2 Suppl):6-12.

- Matta M.K., et al. (2010). Effect of sunscreen application on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA, 323(3):256-67.

- Nash J.F., et al. (2006). Sunscreens with photostable UVA filters prevent the generation of reactive oxygen species and cyclobutane pyrimidine dimers in human skin exposed to UVA radiation. Pigment Cell Research, 19(4):364-74.

Hydrogenated Polydecene

Other name: Puresyn; 1-Decene, homopolymer, hydrogenated; Nomcort HP-100

Function: Solvent, Fragrance, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Hydrogenated Polydecene:

Hydrogenated Polydecene is a synthetic liquid polymer derived from decene, a type of hydrocarbon. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Hydrogenated Polydecene is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Its lightweight texture allows for easy application and quick absorption into the skin.

3. Usage Hydrogenated Polydecene:

When using products containing Hydrogenated Polydecene, it is important to patch test first to check for any allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating products with this ingredient into their skincare routine. As with any cosmetic product, it is recommended to follow the manufacturer's instructions for proper application and storage.

4. References:

- "Hydrogenated Polydecene" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/hydrogenated-polydecene

- "Hydrogenated Polydecene" in Truth in Aging, https://www.truthinaging.com/ingredients/hydrogenated-polydecene

- "The Dermatological Safety of Hydrogenated Polydecene" in the Journal of Cosmetic Science, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110002/

Potassium Cetyl Phosphate

Function: Emulsifying, Surfactant

1. Definition Potassium Cetyl Phosphate:

Potassium Cetyl Phosphate is a potassium salt of cetyl phosphate, an ester of cetyl alcohol and phosphoric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Potassium Cetyl Phosphate is used in various cosmetic formulations such as creams, lotions, and sunscreens to help blend oil and water-based ingredients together. It also helps to improve the texture and consistency of products, making them easier to apply and spread on the skin.

3. Usage Potassium Cetyl Phosphate:

When using products containing Potassium Cetyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product to check for any adverse reactions. Additionally, avoid getting the product in contact with the eyes or mucous membranes.

4. References:

- "Potassium Cetyl Phosphate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." Truth In Aging, www.truthinaging.com/ingredients/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." SpecialChem, www.specialchem.com/inci/potassium-cetyl-phosphate

Ammonium Acryloyldimethyltaurate/VP Copolymer

Other name: Aristoflex AVC

Function: Viscosity Controlling

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Methylpropanediol

Function: Solvent

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

Polyester 5

Function: Viscosity Controlling, Film Forming

1. Definition Polyester 5:

Polyester 5, also known as PEG-5 Polyester, is a type of polymer that is commonly used in cosmetics as an emulsifier and surfactant. It is a synthetic compound that is derived from petroleum and is often found in various skincare and hair care products.

2. Use:

Polyester 5 is primarily used in cosmetics as an emulsifier, which helps to blend together ingredients that are not easily mixable, such as oil and water. It also acts as a surfactant, helping to reduce the surface tension of liquids and allowing them to spread more easily. Additionally, Polyester 5 can help to stabilize formulations and improve the texture of products.

3. Usage Polyester 5:

Polyester 5 is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is important to patch test products containing Polyester 5 before using them regularly, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and not to exceed the recommended usage levels to avoid any potential irritation.

4. References:

- "Polyester 5" by The Personal Care Products Council

- "Safety Assessment of PEG-5 Polyester" by Cosmetic Ingredient Review

- "Polyester 5 in Cosmetics" by Cosmeticsinfo.org

Palmitic Acid

Other name: C16; Palmitic Acid

Function: Fragrance, Opacifying, Emollient, Sufactant

1. Definition Palmitic Acid:

Palmitic acid is a saturated fatty acid commonly found in both animals and plants. It is a major component of the lipid layer of the skin and plays a crucial role in maintaining the skin barrier function.

2. Use:

Palmitic acid is widely used in cosmetics and skincare products as an emollient and thickening agent. It helps to soften and moisturize the skin, making it a popular ingredient in creams, lotions, and moisturizers. Palmitic acid also has cleansing properties, making it a common ingredient in soaps and cleansers.

3. Usage Palmitic Acid:

Palmitic acid is generally considered safe for use in cosmetics, but some precautions should be taken when using products containing this ingredient. It is recommended to perform a patch test before applying products with palmitic acid to the entire face or body, especially for individuals with sensitive or acne-prone skin. Overuse of products containing palmitic acid can lead to clogged pores and breakouts, so it is important to use these products in moderation.

4. References:

- Sivakumar, G., & Sivakumar, R. (2016). Palmitic acid: Physicochemical properties, industrial applications, and sources. Journal of the American Oil Chemists' Society, 93(2), 197-212.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

Stearic Acid

Other name: Octadecanoic Acid; C18; Hexyldecyl Stearate

Function: Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

Jojoba Esters

Other name: Jojoba ester

Function: Skin Conditioning, Emollient, Soothing, Moisturising

1. Definition Jojoba Esters:

Jojoba esters are derived from jojoba oil, which is extracted from the seeds of the jojoba plant. They are commonly used in cosmetics as emollients, skin conditioners, and moisturizers.

2. Use:

Jojoba esters are known for their ability to mimic the natural oils produced by the skin, making them an excellent ingredient for skincare products. They help to hydrate and nourish the skin, leaving it soft and smooth. Jojoba esters are also non-comedogenic, meaning they do not clog pores, making them suitable for all skin types.

3. Usage Jojoba Esters:

Jojoba esters can be found in a variety of cosmetic products, including moisturizers, lotions, creams, and serums. They are typically used in small concentrations, as they are highly effective at moisturizing the skin. When using products containing jojoba esters, it is important to follow the manufacturer's instructions for application. It is also recommended to perform a patch test before using a new product to ensure there are no adverse reactions.

4. References:

- Guo, R., & Huang, L. (2013). Nanotechnology-based cosmeceuticals. Boca Raton, FL: CRC Press.

- Ranzato, E., Martinotti, S., & Burlando, B. (2011). Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology, 134(2), 443-449.

- Meier, L., & Stange, R. (2008). The jojoba plant and its liquid wax. Industrial Crops and Products, 28(2), 241-253.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Glyceryl Stearate Citrate

Function: Skin Conditioning, Emollient, Emulsifying

1. Definition Glyceryl Stearate Citrate:

Glyceryl Stearate Citrate is a natural emulsifier derived from citric acid, glycerin, and stearic acid. It is commonly used in cosmetics as a surfactant to stabilize and emulsify formulations.

2. Use:

Glyceryl Stearate Citrate is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall skin feel. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.

3. Usage Glyceryl Stearate Citrate:

When using products containing Glyceryl Stearate Citrate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. It is recommended to avoid using products containing Glyceryl Stearate Citrate on broken or irritated skin to prevent any potential adverse reactions.

4. References:

- "Safety Assessment of Glyceryl Stearate Citrate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Glyceryl Stearate Citrate" by the Environmental Working Group

- "Emulsifiers in Cosmetics" by the Personal Care Products Council.

Polyacrylate Crosspolymer 6

Function: Viscosity Controlling, Emulsion Stabilising

1. Definition Polyacrylate Crosspolymer 6:

Polyacrylate Crosspolymer 6 is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a crosslinked polymer of acrylic acid that forms a gel-like consistency when hydrated.

2. Use:

Polyacrylate Crosspolymer 6 is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to improve the texture and viscosity of the product, allowing for easier application and better spreadability on the skin. Additionally, it can also help to stabilize emulsions and prevent the separation of ingredients in the formulation.

3. Usage Polyacrylate Crosspolymer 6:

When using products containing Polyacrylate Crosspolymer 6, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with this ingredient to ensure compatibility with your skin. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyacrylate Crosspolymer 6" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/polyacrylate-crosspolymer-6

- "Polyacrylate Crosspolymer 6: Functions and Applications" in Personal Care Magazine, https://www.personalcaremagazine.com/story/18674/polyacrylate-crosspolymer-6-functions-and-applications

- "Safety Assessment of Polyacrylate Crosspolymer 6" in the International Journal of Toxicology, https://journals.sagepub.com/doi/abs/10.1177/1091581818783125

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Polyether 1

Function: Viscosity Controlling, Viscosity Increasing Agent

1. Definition Polyether 1:

Polyether 1 is a type of polymer commonly used in cosmetics as an emulsifier, surfactant, or viscosity controlling agent. It is a versatile ingredient that helps to stabilize formulations and improve the texture of cosmetic products.

2. Use:

Polyether 1 is primarily used in cosmetics to create stable emulsions, such as creams and lotions, by reducing the surface tension between different ingredients. It also helps to enhance the spreadability and absorption of products on the skin, making them easier to apply and more effective.

3. Usage Polyether 1:

When using products containing Polyether 1, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products with this ingredient. It is recommended to avoid contact with the eyes and mucous membranes, and to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Polyether 1." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyether-1.

- Sivik, Mark R. "Polyether Surfactants in Cosmetics." Cosmetics & Toiletries, vol. 111, no. 5, 1996, pp. 79-86.

- "Polyether 1 in Cosmetics: Safety and Regulatory Considerations." Personal Care Products Council, www.personalcarecouncil.org/resource-center/polyether-1-in-cosmetics-safety-and-regulatory-considerations/.

Helianthus Annuus (Sunflower) Seed Wax

Function:

1. Definition Helianthus Annuus (Sunflower) Seed Wax:

Helianthus Annuus (Sunflower) Seed Wax is a natural wax derived from the seeds of the sunflower plant. It is commonly used in cosmetics as a vegan alternative to beeswax.

2. Use:

Sunflower seed wax is known for its emollient properties, making it a popular ingredient in skincare products such as lip balms, moisturizers, and creams. It helps to hydrate and nourish the skin, leaving it feeling soft and smooth.

3. Usage Helianthus Annuus (Sunflower) Seed Wax:

Sunflower seed wax can be found in various cosmetic formulations, including lipsticks, lip balms, and body lotions. It is often used as a thickening agent or emollient to improve the texture and consistency of the product. When using products containing sunflower seed wax, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally considered safe for use in cosmetics but should be avoided by individuals with known allergies to sunflower seeds.

4. References:

- International Journal of Cosmetic Science. (2016). Sunflower wax: A valuable plant wax. https://doi.org/10.1111/ics.12314

- Cosmetics & Toiletries. (2018). Sunflower wax: A natural alternative to petrolatum. https://www.cosmeticsandtoiletries.com/formulating/category/natural/Sunflower-Wax-A-Natural-Alternative-to-Petrolatum-487411121.html

- Journal of Oleo Science. (2015). Sunflower wax: A review. https://doi.org/10.5650/jos.ess14268

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Betula Platyphylla Japonica Juice

Function: Skin Conditioning

1. Definition Betula Platyphylla Japonica Juice:

Betula Platyphylla Japonica Juice, also known as Japanese White Birch Juice, is a natural ingredient derived from the sap of the Betula Platyphylla Japonica tree. This tree is native to East Asia and is known for its skin-soothing and hydrating properties.

2. Use:

Betula Platyphylla Japonica Juice is commonly used in cosmetics for its moisturizing and anti-inflammatory benefits. It is often found in skincare products such as lotions, creams, and serums, where it helps to hydrate the skin, reduce redness and irritation, and promote a healthy complexion.

3. Usage Betula Platyphylla Japonica Juice:

When using skincare products containing Betula Platyphylla Japonica Juice, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a small area of skin and wait for any adverse reactions before using it more widely. As with any new skincare ingredient, it is recommended to start with a lower concentration and gradually increase usage as needed.

4. References:

- Lee, S., Kim, Y., Kim, S., Kim, H., & Kim, K. (2019). Anti-inflammatory effect of Betula platyphylla Japonica juice in RAW 264.7 cells. Food Science and Biotechnology, 28(1), 209-215.

- Park, S., Kim, M., Lee, J., & Kim, K. (2017). Antioxidant and anti-inflammatory effects of Betula platyphylla Japonica juice on UVB-induced damage in HaCaT cells. Journal of Photochemistry and Photobiology B: Biology, 173, 1-7.

- Kim, M., Kim, S., Kim, Y., Lee, J., & Kim, K. (2016). Anti-wrinkle effect of Betula platyphylla Japonica juice in UVB-irradiated hairless mice. Journal of Photochemistry and Photobiology B: Biology, 158, 11-17.

Polyglycerin 3

Function: Humectant

1. Definition Polyglycerin 3:

Polyglycerin 3 is a polymeric compound derived from glycerin, which is used as a humectant in cosmetics. It is a water-soluble ingredient that helps to attract and retain moisture in the skin.

2. Use:

Polyglycerin 3 is commonly used in skincare products such as moisturizers, serums, and lotions due to its hydrating properties. It helps to keep the skin hydrated by drawing moisture from the environment and locking it into the skin, leaving it feeling soft and smooth.

3. Usage Polyglycerin 3:

When using products containing Polyglycerin 3, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use products containing Polyglycerin 3 regularly to maintain hydrated and healthy-looking skin.

Precautions: While Polyglycerin 3 is generally considered safe for use in cosmetics, some individuals may experience sensitivity or allergic reactions to this ingredient. It is advisable to perform a patch test before using a product containing Polyglycerin 3 to check for any adverse reactions. If any irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Kwon, J. E., Kim, B. G., & Lee, J. W. (2019). Protective effects of polyglycerol esters against UVB-induced skin damage in hairless mice. Journal of Photochemistry and Photobiology B: Biology, 199, 111598.

- Lee, J. W., Kim, B. G., & Kwon, J. E. (2018). Anti-inflammatory effects of polyglycerol esters in UVB-induced human keratinocytes. International Journal of Molecular Sciences, 19(9), 2593.

- Zhang, Y., Hu, Q., Li, G., Li, W., & Chen, J. (2017). Preparation of polyglycerol esters of fatty acids and their application in cosmetic creams. Industrial Crops and Products, 97, 592-599.

Acacia Decurrens Flower Wax

Function: Skin Conditioning, Emollient, Skin Protecting

1. Definition Acacia Decurrens Flower Wax:

Acacia Decurrens Flower Wax is a natural plant-derived wax obtained from the flowers of Acacia Decurrens, a species of tree native to Australia. It is commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent.

2. Use:

Acacia Decurrens Flower Wax is often used in cosmetics as a natural alternative to synthetic waxes. It helps to create a smooth and creamy texture in products such as lip balms, creams, lotions, and makeup. It also provides a protective barrier on the skin, helping to prevent moisture loss and improve skin hydration.

3. Usage Acacia Decurrens Flower Wax:

Acacia Decurrens Flower Wax can be incorporated into various cosmetic formulations at different concentrations depending on the desired texture and consistency. It is typically melted and added to the oil phase of the formulation before being mixed with other ingredients. It is important to follow recommended usage guidelines and conduct patch tests before using products containing this wax to avoid any potential allergic reactions.

4. References:

- "Acacia Decurrens Flower Wax" by Cosmetics Info

- "Acacia Decurrens Flower Wax in Cosmetics" by Personal Care Magazine

- "The Benefits of Acacia Decurrens Flower Wax in Skincare" by The Eco Well

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Ceramide Np

Other name: Ceramide 3; Ceramide III

Function:

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.