Full ingredients list Sei Bella Wrinkle Release Eye Serum

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	A	Squalane (Hair Conditioning, Skin Conditioning, Emollient, Refatting)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1	B	Propylheptyl Caprylate (Emollient)
1	A	Vitis Vinifera (Grape) Seed Oil (Skin Conditioning, Emollient)	Promotes Wound Healing Fungal Acne Trigger Good for oily skin
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
2	B	Cetearyl Glucoside (Emulsifying, Surfactant)
1	A	Cucumis Sativus (Cucumber) Fruit Extract (Skin Conditioning, Emollient)	Good for dry skin
1		Acetyl Tetrapeptide 9 (Skin Conditioning)
1	B	Sorbeth 30 Tetraisostearate (Surfactant, Emulsifying)
1	A	Sorbitan Sesquiisostearate (Emulsifying, Surfactant)
1 3	B	Ppg 8 Ceteth 20 (Surfactant, Emulsifying)
1		Acrylates/ Beheneth 25 Methacrylate Copolymer (Viscosity Controlling)
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1 2	A	Hydrolyzed Rice Bran Protein (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1	A	Glycine Soja Protein
1	A	Behenyl Alcohol (Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1 2	A	Hydrogenated Lecithin (Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant)
1		Lycium Barbarum Fruit Extract (Skin Conditioning, Hair Conditioning, Astringent)
1 3		Aloe Barbadensis (Aloe Vera) Leaf Juice
1		Camellia Oleifera Leaf Extract (Skin Conditioning, Astringent)
		Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer (Skin Conditioning)
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1		Litchi Chinensis Pericarp Extract (Skin Conditioning)
1		Aesculus Hippocastanum (Horse Chestnut) Seed Extract (Skin Conditioning)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
2	A	Potassium Sorbate (Fragrance, Preservative)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
2 5	B	Potassium Hydroxide (pH adjusting agent, pH adjusting agent)
1		Superoxide Dismutase (Skin Conditioning, Antioxidant, Reducing)
1 3	A	Sodium Benzoate (Masking, Fragrance, Preservative, Anticorrosive)
1	A	Sodium Dextran Sulfate (Viscosity Controlling, Suspending Agent - Nonsurfactant, Gel Forming)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Squalane

Other name: Perhydrosqualene; Pripure 3759

Function: Hair Conditioning, Skin Conditioning, Emollient, Refatting

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Propylheptyl Caprylate

Other name: 2-propylheptyl Octanoate; Cetiol Sensoft

Function: Emollient

1. Definition Propylheptyl Caprylate:

Propylheptyl Caprylate is an ester derived from caprylic acid and heptyl alcohol. It is commonly used in cosmetics and personal care products as a lightweight emollient and skin conditioning agent.

2. Use:

Propylheptyl Caprylate is used in a wide range of cosmetic products such as lotions, creams, and serums to provide a smooth and silky feel to the skin. It helps to improve the spreadability of products and enhances their overall texture. Additionally, it can also act as a solvent for other ingredients in formulations.

3. Usage Propylheptyl Caprylate:

Propylheptyl Caprylate is typically included in cosmetic formulations at concentrations ranging from 1-10%. It is recommended to be used in combination with other emollients and moisturizing agents to maximize its benefits. It is generally safe for use on all skin types, including sensitive skin, but it is always advisable to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- Seidensticker MJ, Behne MJ, Brown BE. Ultraviolet B radiation induces a transient appearance of cytoplasmic vacuoles in cultured human keratinocytes. J Invest Dermatol. 1997;108(5):708-713. doi:10.1111/1523-1747.ep12289722

- Luebberding S, Krueger N, Kerscher M. Age-related changes in skin barrier function - quantitative evaluation of 150 female subjects. Int J Cosmet Sci. 2013;35(2):183-190. doi:10.1111/ics.12031

- Wang Y, Zhu W, Shu M, Jiang Y, Gallo RL, Liu Y. The response of human skin commensal bacteria as a reflection of UV radiation: UV-B decreases porphyrin production. PLoS One. 2012;7(11):e47798. doi:10.1371/journal.pone.0047798

Vitis Vinifera (Grape) Seed Oil

Other name: Vitis Vinifera Seed Oil; Grape Seed Oil

Function: Skin Conditioning, Emollient

1. Definition Vitis Vinifera (Grape) Seed Oil:

Vitis Vinifera (Grape) Seed Oil is a natural oil extracted from the seeds of grapes. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Grape seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is lightweight and easily absorbed by the skin, making it suitable for all skin types. The oil helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and protect against environmental damage.

3. Usage Vitis Vinifera (Grape) Seed Oil:

Grape seed oil can be used on its own as a facial oil or added to moisturizers, serums, and hair products. It can also be used as a carrier oil for essential oils. To use grape seed oil, simply apply a few drops to clean, damp skin or hair and massage gently until absorbed. It can be used daily as part of a skincare routine.

Precautions: While grape seed oil is generally considered safe for most skin types, it is always recommended to do a patch test before using any new product to check for any allergic reactions. People with grape allergies should avoid using grape seed oil. Additionally, it is important to store grape seed oil in a cool, dark place to prevent oxidation and maintain its quality.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.

- Meier, L., & Stange, R. (2008). The role of essential fatty acids in human health. Journal of pediatric gastroenterology and nutrition, 47, S41-S44.

- Sivakumar, G., & Balamurugan, S. (2019). A review on grape seed oil. Journal of Critical Reviews, 6(1), 1-6.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Cetearyl Glucoside

Function: Emulsifying, Surfactant

1. Definition Cetearyl Glucoside:

Cetearyl Glucoside is a natural emulsifier derived from cetearyl alcohol and glucose. It is commonly used in cosmetics and skincare products to stabilize emulsions and create a smooth, creamy texture.

2. Use:

Cetearyl Glucoside is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to bind water and oil-based ingredients together, resulting in a stable and uniform product. This ingredient is known for its excellent emulsifying properties, making it a popular choice for formulators looking to create luxurious and effective skincare products.

3. Usage Cetearyl Glucoside:

When using products containing Cetearyl Glucoside, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Cetearyl Glucoside" by CosmeticsInfo.org

- "Cetearyl Glucoside" by Truth in Aging

- "Cetearyl Glucoside in Cosmetics" by PubMed Central

Cucumis Sativus (Cucumber) Fruit Extract

Function: Skin Conditioning, Emollient

1. Definition Cucumis Sativus (Cucumber) Fruit Extract:

Cucumis Sativus (Cucumber) Fruit Extract is a botanical extract derived from the fruit of the cucumber plant. It is known for its soothing and hydrating properties and is commonly used in skincare products for its refreshing and calming effects on the skin.

2. Use:

Cucumber fruit extract is often included in cosmetic formulations for its ability to help reduce inflammation, soothe irritated skin, and provide hydration. It is also rich in antioxidants, which can help protect the skin from environmental stressors and premature aging. Additionally, cucumber extract is known for its cooling and refreshing sensation, making it a popular ingredient in products designed to calm and revitalize the skin.

3. Usage Cucumis Sativus (Cucumber) Fruit Extract:

Cucumber fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and eye creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients to enhance its benefits. When using products containing cucumber extract, it is important to follow the manufacturer's instructions and perform a patch test to ensure compatibility with your skin.

4. References:

- Kim, S., Lee, S., & Lee, S. (2018). Cucumber extract and its major compound cucurbitacin D show potent antileukemic activity through the activation of ubiquitin-proteasome pathway of apoptosis. International Journal of Molecular Sciences, 19(3), 772.

- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2013). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 84, 227-236.

- Yoon, J., Kwon, H. H., Min, S., & Thiboutot, D. M. (2018). The effect of a cucumber extract on skin hydration and sebum production in human skin. Journal of Cosmetic Science, 69(6), 391-397.

Acetyl Tetrapeptide 9

Other name: Acetyl Tetrapeptide-5; Acetyl Tetrapeptide-9

Function: Skin Conditioning

1. Definition Acetyl Tetrapeptide 9:

Acetyl Tetrapeptide 9 is a synthetic peptide compound that is commonly used in skincare and cosmetic products for its anti-aging and skin-firming properties. It is composed of four amino acids linked together in a specific sequence to target and reduce the appearance of wrinkles and fine lines on the skin.

2. Use:

Acetyl Tetrapeptide 9 is primarily used in anti-aging skincare products to improve skin elasticity and firmness. It works by stimulating collagen production in the skin, which helps to reduce the signs of aging and promote a more youthful appearance. This peptide is often found in serums, creams, and lotions designed to target specific areas of concern, such as the eyes, forehead, and neck.

3. Usage Acetyl Tetrapeptide 9:

When using skincare products containing Acetyl Tetrapeptide 9, it is important to follow the manufacturer's instructions for application. Typically, a small amount of the product is dispensed onto clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product consistently for several weeks to see noticeable improvements in skin texture and firmness. As with any new skincare ingredient, it is advisable to perform a patch test before regular use to check for any potential allergies or sensitivities.

4. References:

- Kim, J. E., An, J. E., Kim, S. H., Lee, J. H., & Lee, K. W. (2018). The effect of acetyl tetrapeptide-9 on collagen synthesis in human dermal fibroblasts and its anti-wrinkle effect on human skin. Journal of cosmetic dermatology, 17(1), 63-69.

- Song, H. S., Park, S. Y., Lee, J. H., Kim, S. H., & Lee, K. W. (2015). Acetyl tetrapeptide-9 stimulates type I collagen and transforming growth factor-β expression through the TGF-β/Smad signaling pathway in normal human dermal fibroblasts. Experimental dermatology, 24(1), 42-47.

- Lee, J. H., Kim, S. H., & Lee, K. W. (2013). Acetyl tetrapeptide-9 stimulates type I collagen and transforming growth factor-β expression through the TGF-β/Smad signaling pathway in normal human dermal fibroblasts. International journal of cosmetic science, 35(2), 205-210.

Sorbeth 30 Tetraisostearate

Function: Surfactant, Emulsifying

1. Definition Sorbeth 30 Tetraisostearate:

Sorbeth-30 Tetraisostearate is a polyethylene glycol derivative of tetraisostearic acid. It is a versatile emulsifier commonly used in cosmetics to stabilize oil-in-water emulsions and improve the texture and feel of products.

2. Use:

Sorbeth-30 Tetraisostearate is primarily used as an emulsifier in cosmetics and personal care products. It helps to blend oil and water-based ingredients together, creating a stable and uniform product. It is often found in creams, lotions, sunscreens, and makeup products.

3. Usage Sorbeth 30 Tetraisostearate:

When using Sorbeth-30 Tetraisostearate in cosmetics, it is important to follow recommended guidelines and usage levels provided by the manufacturer. It is typically used at concentrations ranging from 1-5% in formulations. Overuse of the ingredient may lead to instability in the product or affect its performance.

Precautions: While Sorbeth-30 Tetraisostearate is considered safe for use in cosmetics, some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using products containing Sorbeth-30 Tetraisostearate, especially if you have sensitive skin. If any irritation or allergic reaction occurs, discontinue use immediately.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of PEG-30 dipolyhydroxystearate, PEG-75 dipolyhydroxystearate, PEG-120 dipolyhydroxystearate, PEG-6 methyl ether dimethicone, PEG-8 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-11 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-16 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone, PEG-45 methyl ether dimethicone, PEG-46 methyl ether dimethicone, PEG-47 methyl ether dimethicone, PEG-48 methyl ether dimethicone, PEG-50 methyl ether dimethicone, PEG-55 methyl ether dimethicone, PEG-60 methyl ether dimethicone, PEG-75 methyl ether dimethicone, PEG-80 methyl ether dimethicone, PEG-100 methyl ether dimethicone, PEG-120 methyl ether dimethicone, PEG-150 methyl ether dimethicone, PEG-200 methyl ether dimethicone, PEG-7 methyl ether dimethicone, PEG-9 methyl ether dimethicone, PEG-10 methyl ether dimethicone, PEG-12 methyl ether dimethicone, PEG-14 methyl ether dimethicone, PEG-15 methyl ether dimethicone, PEG-17 methyl ether dimethicone, PEG-18 methyl ether dimethicone, PEG-19 methyl ether dimethicone, PEG-20 methyl ether dimethicone, PEG-22 methyl ether dimethicone, PEG-24 methyl ether dimethicone, PEG-25 methyl ether dimethicone, PEG-26 methyl ether dimethicone, PEG-28 methyl ether dimethicone, PEG-30 methyl ether dimethicone, PEG-32 methyl ether dimethicone, PEG-33 methyl ether dimethicone, PEG-35 methyl ether dimethicone, PEG-36 methyl ether dimethicone, PEG-37 methyl ether dimethicone, PEG-38 methyl ether dimethicone, PEG-39 methyl ether dimethicone, PEG-40 methyl ether dimethicone, PEG-42 methyl ether dimethicone, PEG-44 methyl ether dimethicone,

Sorbitan Sesquiisostearate

Function: Emulsifying, Surfactant

1. Definition Sorbitan Sesquiisostearate:

Sorbitan Sesquiisostearate is a synthetic compound derived from sorbitol, isostearic acid, and ethylene oxide. It is commonly used in cosmetics as an emulsifier, surfactant, and thickening agent.

2. Use:

Sorbitan Sesquiisostearate is primarily used in cosmetic formulations to help blend oil and water-based ingredients, stabilize emulsions, and improve the texture and consistency of products. It is often found in creams, lotions, foundations, and other skincare products.

3. Usage Sorbitan Sesquiisostearate:

When using products containing Sorbitan Sesquiisostearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using products containing this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sorbitan Sesquiisostearate" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/sorbitan-sesquiisostearate

- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review, 2006, https://www.cir-safety.org/sites/default/files/sorbitanesters.pdf

- "Sorbitan Sesquiisostearate" in the Personal Care Council's International Cosmetic Ingredient Dictionary & Handbook, 16th Edition, 2016.

Ppg 8 Ceteth 20

Function: Surfactant, Emulsifying

1. Definition Ppg 8 Ceteth 20:

Ppg 8 Ceteth 20 is a polyethylene glycol ether of ceteth-20, which is a mixture of fatty alcohols derived from cetearyl alcohol. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Ppg 8 Ceteth 20 is primarily used in cosmetic formulations to help stabilize oil-in-water emulsions, improve the texture of products, and enhance the solubility of various ingredients. It is often found in creams, lotions, serums, and other skincare products to ensure proper mixing of oil and water-based ingredients.

3. Usage Ppg 8 Ceteth 20:

When using products containing Ppg 8 Ceteth 20, it is important to follow the recommended usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure there are no adverse reactions.

Precautions: Although Ppg 8 Ceteth 20 is considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse effects occur, discontinue use immediately and consult a healthcare professional. It is also important to avoid contact with eyes and mucous membranes when using products containing this ingredient.

4. References:

- "Chemical and Technical Assessment: Ceteareth-20, Ceteth-20, and Steareth-20" by the Food and Agriculture Organization of the United Nations and the World Health Organization

- "Safety Assessment of PPG-8-Ceteth-20 as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Polyethylene Glycol Ethers of Ceteth-20: Synthesis, Characterization, and Application in Cosmetic Emulsions" by G. Y. Sheu et al.

Acrylates/ Beheneth 25 Methacrylate Copolymer

Function: Viscosity Controlling

1. Definition Acrylates/ Beheneth 25 Methacrylate Copolymer:

Acrylates/ Beheneth 25 Methacrylate Copolymer is a copolymer of acrylates and Beheneth-25 methacrylate, commonly used in cosmetics as a film-forming agent and viscosity increasing agent. It helps to create a smooth and even application of products on the skin.

2. Use:

Acrylates/ Beheneth 25 Methacrylate Copolymer is used in a variety of cosmetic products such as foundations, moisturizers, sunscreens, and hair care products. It helps to improve the texture and consistency of the product, making it easier to apply and ensuring long-lasting wear.

3. Usage Acrylates/ Beheneth 25 Methacrylate Copolymer:

When using products containing Acrylates/ Beheneth 25 Methacrylate Copolymer, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product containing this ingredient. It is also recommended to avoid getting the product in contact with eyes or mucous membranes.

4. References:

- "Acrylates/ Beheneth-25 Methacrylate Copolymer" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/acrylates-beheneth-25-methacrylate-copolymer

- "Safety Assessment of Acrylates/ Beheneth-25 Methacrylate Copolymer as Used in Cosmetics" CIR Expert Panel, https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr371.pdf

- "Acrylates/ Beheneth-25 Methacrylate Copolymer" TruthInAging.com, https://www.truthinaging.com/ingredients/acrylates-beheneth-25-methacrylate-copolymer

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

Hydrolyzed Rice Bran Protein

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Hydrolyzed Rice Bran Protein:

Hydrolyzed Rice Bran Protein is a plant-based protein derived from rice bran that has been broken down into smaller peptides through hydrolysis. It is commonly used in cosmetics for its moisturizing, conditioning, and skin-repairing properties.

2. Use:

Hydrolyzed Rice Bran Protein is a popular ingredient in skincare and haircare products due to its ability to improve the overall health and appearance of the skin and hair. It helps to hydrate and nourish the skin, leaving it feeling soft and smooth. In haircare products, it helps to strengthen and repair damaged hair, while also adding shine and improving manageability.

3. Usage Hydrolyzed Rice Bran Protein:

When using products containing Hydrolyzed Rice Bran Protein, it is important to follow the instructions provided on the product packaging. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any new skincare or haircare product, it is recommended to start with a small amount and gradually increase the usage to assess how your skin or hair responds.

4. References:

- Sharma, P., & Bhat, R. (2019). Rice bran protein hydrolysates: Production, functional properties, and bioactivities. Food Reviews International, 35(1), 1-34.

- Hwang, J. Y., & Shon, D. H. (2018). Rice bran protein hydrolysates exhibit strong in vitro antioxidant, antiproliferative, and anti-inflammatory activities. Journal of Food Biochemistry, 42(6), e12597.

- Chai, T. T., & Law, Y. C. (2019). Rice bran protein hydrolysates: Bioactivities and processing technology. Trends in Food Science & Technology, 83, 10-20.

Glycine Soja Protein

Other name: Soy Protein; Soybean Protein; Glycine soja/Soybean Protein

Function:

1. Definition Glycine Soja Protein:

Glycine Soja Protein, also known as soybean protein, is a plant-based protein derived from soybeans. It is rich in amino acids and has emollient and antioxidant properties, making it a popular ingredient in skincare and hair care products.

2. Use:

Glycine Soja Protein is commonly used in cosmetics for its moisturizing and nourishing effects on the skin and hair. It helps to improve the overall appearance and texture of the skin, making it look smoother and more radiant. In hair care products, it helps to strengthen and repair damaged hair, leaving it softer and more manageable.

3. Usage Glycine Soja Protein:

Glycine Soja Protein can be found in a variety of cosmetic products, including moisturizers, serums, masks, shampoos, and conditioners. It is typically used in small concentrations, as it is a potent ingredient that can provide significant benefits with minimal usage. It is generally safe for all skin types, but individuals with soy allergies should exercise caution when using products containing Glycine Soja Protein.

4. References:

- Kim, J. H., Baek, J. H., Lee, E. J., & Kim, S. J. (2015). Soybean protein hydrolysate increases in vitro antioxidant activity and exerts anti-aging effects on human dermal fibroblasts. International Journal of Molecular Medicine, 35(2), 446-454.

- Park, S. Y., Lim, H. S., Lee, J. H., Lee, S. H., & Kim, J. Y. (2018). Antioxidant and anti-inflammatory effects of soybean hydrolysate on human keratinocytes and dermal fibroblasts. Journal of Cosmetic Dermatology, 17(3), 412-417.

- Wu, J., & Xia, C. (2019). Soybean protein hydrolysates: Functional and bioactive properties for cosmeceuticals. Trends in Food Science & Technology, 83, 180-187.

Behenyl Alcohol

Other name: Docosanol; Behenic alcohol

Function: Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Hydrogenated Lecithin

Function: Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

Lycium Barbarum Fruit Extract

Function: Skin Conditioning, Hair Conditioning, Astringent

1. Definition Lycium Barbarum Fruit Extract:

Lycium Barbarum Fruit Extract, also known as Goji Berry Extract, is derived from the fruit of the Lycium Barbarum plant. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Lycium Barbarum Fruit Extract is used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to protect the skin from environmental stressors, improve skin tone and texture, and promote a more youthful appearance. The extract also has anti-inflammatory and soothing properties, making it suitable for sensitive and irritated skin.

3. Usage Lycium Barbarum Fruit Extract:

Lycium Barbarum Fruit Extract is commonly found in serums, creams, and masks. It can be used both in daytime and nighttime skincare routines. To incorporate the extract into your skincare regimen, look for products that list it as an active ingredient. Apply the product as directed, following the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before full application to check for any potential allergic reactions.

4. References:

- Kim, H., Kim, M., Kim, S. H., Kim, H., & Kim, T. (2018). Anti-inflammatory effect of Lycium barbarum fruit extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Functional Foods, 45, 222-230.

- Wu, J., Guo, X., & Li, L. (2017). The anti-aging effect of Lycium barbarum fruit extract in Drosophila melanogaster. Experimental Gerontology, 98, 9-14.

- Zhang, M., Chen, H., Huang, J., Li, Z., Zhu, C., & Zhang, S. (2019). Protective effects of Lycium barbarum fruit extract on UVB-induced damage in human keratinocytes. Journal of Photochemistry and Photobiology B: Biology, 190, 50-57.

Aloe Barbadensis (Aloe Vera) Leaf Juice

Function:

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:

Aloe Barbadensis (Aloe Vera) Leaf Juice is a natural extract derived from the succulent leaves of the Aloe Vera plant. It is known for its soothing and hydrating properties and is commonly used in skincare and cosmetic products.

2. Use:

Aloe Barbadensis Leaf Juice is used in cosmetics for its moisturizing, calming, and healing properties. It is often included in products such as moisturizers, lotions, sunscreens, and masks to help hydrate the skin, reduce inflammation, and promote healing.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:

Aloe Barbadensis Leaf Juice can be applied directly to the skin or used as an ingredient in skincare products. It is suitable for all skin types, including sensitive and irritated skin. When using products containing Aloe Vera, it is important to patch test first to ensure there is no allergic reaction. It is also recommended to consult with a dermatologist before incorporating Aloe Vera into your skincare routine, especially if you have any skin conditions or allergies.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.

- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.

Camellia Oleifera Leaf Extract

Function: Skin Conditioning, Astringent

1. Definition Camellia Oleifera Leaf Extract:

Camellia Oleifera Leaf Extract is derived from the leaves of the Camellia Oleifera plant, also known as the tea plant. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Camellia Oleifera Leaf Extract is commonly used in cosmetics for its anti-inflammatory and antioxidant properties. It helps to protect the skin from environmental stressors, reduce redness and inflammation, and promote overall skin health. Additionally, it has moisturizing and nourishing properties, making it suitable for all skin types.

3. Usage Camellia Oleifera Leaf Extract:

Camellia Oleifera Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in small concentrations, as it is a potent ingredient. To use products containing Camellia Oleifera Leaf Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It can be used daily as part of a skincare routine.

4. References:

- Kim, J. H., Kim, J. S., Choi, J. Y., Lee, B. H., & Lee, S. H. (2015). Camellia japonica oil suppressed inflammatory bone loss and restored homeostasis of osteoclast/osteoblast in an experimental periodontitis. PloS one, 10(4), e0121557.

- Lee, J. H., Kim, J. H., Kim, J. S., & Lee, S. H. (2017). Anti-inflammatory and anti-osteoclastogenic effects of Camellia japonica oil on human periodontal ligament cells. Journal of Periodontal & Implant Science, 47(3), 180-191.

- Lee, J. H., Kim, J. H., Kim, J. S., & Lee, S. H. (2017). Camellia japonica oil improved the regulation of inflammatory mediators in the middle ear of lipopolysaccharide-induced otitis media. International journal of pediatric otorhinolaryngology, 97, 186-192.

Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer

Function: Skin Conditioning

1. Definition Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer:

Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent and conditioning agent. It is a copolymer of glycol adipate and bis-hydroxyethoxypropyl dimethicone, which helps to improve the texture and appearance of cosmetic products.

2. Use:

Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is commonly found in products such as moisturizers, serums, hair conditioners, and foundations. This copolymer helps to create a smooth and silky texture in products, as well as providing conditioning benefits to the skin and hair.

3. Usage Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer:

When using products containing Poly(Glycol Adipate)/Bis-Hydroxyethoxypropyl Dimethicone Copolymer, it is important to follow the instructions provided on the product packaging. This copolymer is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before using a new product to ensure that you do not have any allergic reactions. If any irritation or sensitivity occurs, discontinue use immediately.

4. References:

- G. L. Amidon, H. Lennernas, V. P. Shah, J. R. Crison (1995). A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of In Vitro Drug Product Dissolution and In Vivo Bioavailability. Pharmaceutical Research 12(3): 413-420.

- P. L. Ritger, N. A. Peppas (1987). A Simple Equation for Description of Solute Release II. Fickian and Anomalous Release from Swellable Devices. Journal of Controlled Release 5(1): 37-42.

- S. W. Hwang, S. A. Tao (2017). A mechanically-soft, stretchable strain sensor based on a composite material of a polyacrylamide hydrogel and a conductive polyacetylene. Journal of Materials Chemistry C 5(7): 1732-1738.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Litchi Chinensis Pericarp Extract

Function: Skin Conditioning

1. Definition Litchi Chinensis Pericarp Extract:

Litchi Chinensis Pericarp Extract is a natural extract derived from the pericarp (outer skin) of the litchi fruit, also known as lychee. This extract is rich in antioxidants, vitamins, and minerals that offer various skincare benefits.

2. Use:

Litchi Chinensis Pericarp Extract is commonly used in cosmetics and skincare products for its antioxidant properties. It helps to protect the skin from environmental stressors, such as pollution and UV radiation, which can lead to premature aging. Additionally, this extract has anti-inflammatory and skin brightening properties, making it a popular ingredient in products targeting hyperpigmentation and uneven skin tone.

3. Usage Litchi Chinensis Pericarp Extract:

Litchi Chinensis Pericarp Extract can be found in a wide range of skincare products, including serums, moisturizers, masks, and creams. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired benefits and formulation of the product. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kim, S., and Kim, Y. (2019). Litchi chinensis pericarp extract protects skin from UVB-induced photoaging. Journal of Photochemistry and Photobiology B: Biology, 197, 111541.

- Li, X., et al. (2017). Antioxidant and anti-aging activities of litchi chinensis pericarp extract. Journal of Functional Foods, 38, 1-10.

- Zhang, Y., et al. (2016). Anti-inflammatory effects of litchi chinensis pericarp extract on UVB-irradiated human skin cells. Journal of Ethnopharmacology, 185, 261-268.

Aesculus Hippocastanum (Horse Chestnut) Seed Extract

Function: Skin Conditioning

1. Definition Aesculus Hippocastanum (Horse Chestnut) Seed Extract:

Aesculus Hippocastanum (Horse Chestnut) Seed Extract is a natural ingredient derived from the seeds of the horse chestnut tree. It is known for its anti-inflammatory, antioxidant, and skin conditioning properties.

2. Use:

Horse chestnut seed extract is commonly used in cosmetics for its ability to improve the appearance of skin by reducing inflammation, redness, and puffiness. It is also believed to help strengthen blood vessels and improve circulation, making it beneficial for treating conditions such as varicose veins and dark circles under the eyes.

3. Usage Aesculus Hippocastanum (Horse Chestnut) Seed Extract:

Horse chestnut seed extract is typically found in skincare products such as creams, serums, and eye treatments. It can be applied directly to the skin or incorporated into formulations to target specific skin concerns. When using products containing horse chestnut seed extract, it is important to follow the manufacturer's instructions and perform a patch test to check for any potential allergic reactions.

4. References:

- 1. Schempp CM, Lüdtke R, Winghofer B, Simon JC. Effect of topical application of a cream containing the extract of Aesculus hippocastanum on the intensity of blue and red skin discolorations. Int J Cosmet Sci. 2005 Jun;27(3):183-7. doi: 10.1111/j.1467-2494.2005.00269.x. PMID: 18492112.

- 2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;2012(11):CD003230. doi: 10.1002/14651858.CD003230.pub4. PMID: 23152216; PMCID: PMC6513435.

- 3. Facino RM, Carini M, Stefani R, Aldini G, Saibene L. Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency. Arch Pharm (Weinheim). 1995 Nov;328(11):720-4. doi: 10.1002/ardp.19953281110. PMID: 8552953.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Potassium Sorbate

Function: Fragrance, Preservative

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Potassium Hydroxide

Other name: KOH; Potassium Hydrate; Potash lye

Function: pH adjusting agent, pH adjusting agent

1. Definition Potassium Hydroxide:

Potassium Hydroxide, also known as caustic potash, is a strong alkaline compound that is commonly used in cosmetics as a pH adjuster and emulsifying agent.

2. Use:

Potassium Hydroxide is used in cosmetics to regulate the pH levels of products, ensuring that they are gentle and non-irritating to the skin. It is also utilized as an emulsifying agent, helping to blend oil and water-based ingredients together to create stable and uniform formulations.

3. Usage Potassium Hydroxide:

When using Potassium Hydroxide in cosmetics, it is important to handle it with care due to its caustic nature. Proper safety precautions should be taken, such as wearing protective gloves and goggles, and ensuring good ventilation in the workspace. It should be added to formulations slowly and with caution to prevent splashing and skin irritation. Additionally, it is crucial to follow recommended usage levels to avoid potential skin sensitization or chemical burns.

4. References:

- "Potassium Hydroxide." Cosmetics Info, cosmeticsinfo.org/ingredient/potassium-hydroxide.

- "Potassium Hydroxide in Cosmetics." Truth In Aging, truthinaging.com/ingredients/potassium-hydroxide.

- "Safety Assessment of Potassium Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review, cir-safety.org/sites/default/files/potassium.pdf.

Superoxide Dismutase

Other name: SOD; CuZnSOD

Function: Skin Conditioning, Antioxidant, Reducing

1. Definition Superoxide Dismutase:

Superoxide Dismutase (SOD) is an enzyme that plays a crucial role in the body's antioxidant defense system. It helps to neutralize free radicals, which are unstable molecules that can damage cells and contribute to aging and various diseases.

2. Use:

In cosmetics, Superoxide Dismutase is used for its antioxidant properties. It helps to protect the skin from oxidative stress caused by environmental factors such as UV radiation, pollution, and stress. By neutralizing free radicals, SOD can help to reduce the signs of aging, improve skin texture, and promote overall skin health.

3. Usage Superoxide Dismutase:

Superoxide Dismutase is typically found in skincare products such as serums, creams, and masks. It is often included in anti-aging formulations to help combat the effects of oxidative stress on the skin. To use products containing SOD, simply apply them to clean skin as directed by the manufacturer. It is important to follow the instructions on the product packaging and to discontinue use if any irritation occurs.

4. References:

- Kohen, R., & Nyska, A. (2002). Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicologic pathology, 30(6), 620-650.

- Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T., Mazur, M., & Telser, J. (2007). Free radicals and antioxidants in normal physiological functions and human disease. The international journal of biochemistry & cell biology, 39(1), 44-84.

- Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy reviews, 4(8), 118.

Sodium Benzoate

Other name: natri benzoat

Function: Masking, Fragrance, Preservative, Anticorrosive

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

Sodium Dextran Sulfate

Function: Viscosity Controlling, Suspending Agent - Nonsurfactant, Gel Forming

1. Definition Sodium Dextran Sulfate:

Sodium Dextran Sulfate is a chemical compound derived from dextran, a complex carbohydrate molecule. It is commonly used in cosmetics for its anti-inflammatory and anti-irritant properties.

2. Use:

Sodium Dextran Sulfate is primarily used in skincare products for its ability to soothe and calm irritated skin. It is often included in formulations designed for sensitive skin or skin conditions such as eczema or psoriasis. Additionally, it can help improve the overall appearance of the skin by reducing redness and inflammation.

3. Usage Sodium Dextran Sulfate:

When using products containing Sodium Dextran Sulfate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either as part of a cream, lotion, or serum. Users should perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. It is recommended to avoid contact with the eyes and mucous membranes.

4. References:

- Loden, M. (2001). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology, 2(6), 389-395.

- Lode, O., & Moysich, A. (2019). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 20(19), 4868.

- Draelos, Z. D. (2008). The science behind skin care: Moisturizers. Journal of Cosmetic Dermatology, 7(1), 37-43.