Full ingredients list SVR Topialyse Barriere Cream

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
2	A	Hydrogenated Polydecene (Solvent, Fragrance, Hair Conditioning, Skin Conditioning, Emollient)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	B	Ethylhexyl Stearate (Skin Conditioning, Emollient)	Fungal Acne Trigger
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Crambe Abyssinica Seed Oil Phytosterol Esters (Skin Conditioning, Hair Conditioning)	Fungal Acne Trigger
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1		Polyester 7 (Skin Conditioning, Viscosity Controlling, Film Forming)
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1		Xylitylglucoside (Humectant, Skin Conditioning)
1		Neopentyl Glycol Diheptanoate (Skin Conditioning, Emollient, Viscosity Increasing Agent)
1	A	1,2-Hexanediol (Solvent)
1	A	Behenyl Alcohol (Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding)
1		C10 18 Triglycerides (Solvent, Skin Conditioning, Emollient)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1		Anhydroxylitol (Skin Conditioning, Humectant)
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
1 3	B	Ceteareth 33 (Surfactant, Emulsifying, Cleansing)
1		Ammonium Acryloyldimethyltaurate/VP Copolymer (Viscosity Controlling)
		Camelina Sativa Seed Oil/Palm Oil Aminopropanediol Esters
2 3	A	Tocopheryl Acetate (Skin Conditioning, Antioxidant)	Anti Aging
1		Xylitol (Humectant, Skin Conditioning, Flavoring Agent)
3	A	Peg 75 Stearate (Surfactant)	Fungal Acne Trigger
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1 3	B	Ceteth 20 (Surfactant, Emulsifying, Cleansing)
1 3	B	Steareth 20 (Surfactant, Emulsifying, Sufactant)
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
5	B	Triethanolamine (Masking, Fragrance, pH adjusting agent, pH adjusting agent, Emulsifying, Surfactant)
1 2	A	Hydrolyzed Rice Protein (Skin Conditioning, Antistatic Agent, Hair Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Hydrogenated Polydecene

Other name: Puresyn; 1-Decene, homopolymer, hydrogenated; Nomcort HP-100

Function: Solvent, Fragrance, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Hydrogenated Polydecene:

Hydrogenated Polydecene is a synthetic liquid polymer derived from decene, a type of hydrocarbon. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Hydrogenated Polydecene is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Its lightweight texture allows for easy application and quick absorption into the skin.

3. Usage Hydrogenated Polydecene:

When using products containing Hydrogenated Polydecene, it is important to patch test first to check for any allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating products with this ingredient into their skincare routine. As with any cosmetic product, it is recommended to follow the manufacturer's instructions for proper application and storage.

4. References:

- "Hydrogenated Polydecene" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/hydrogenated-polydecene

- "Hydrogenated Polydecene" in Truth in Aging, https://www.truthinaging.com/ingredients/hydrogenated-polydecene

- "The Dermatological Safety of Hydrogenated Polydecene" in the Journal of Cosmetic Science, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110002/

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Ethylhexyl Stearate

Function: Skin Conditioning, Emollient

1. Definition Ethylhexyl Stearate:

Ethylhexyl Stearate is a synthetic ester derived from stearic acid and 2-ethylhexanol. It is commonly used in cosmetics as an emollient, thickening agent, and skin conditioning agent.

2. Use:

Ethylhexyl Stearate is primarily used in skincare and haircare products for its ability to moisturize and soften the skin. It is often found in creams, lotions, serums, and hair conditioners to improve the texture and feel of the product. Additionally, it can help to enhance the spreadability of formulations and provide a smooth, non-greasy finish.

3. Usage Ethylhexyl Stearate:

When using products containing Ethylhexyl Stearate, it is important to be aware of potential skin sensitivities or allergies. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or adverse reactions. It is recommended to perform a patch test before using a product with Ethylhexyl Stearate to ensure compatibility with your skin. Additionally, it is advisable to follow the manufacturer's instructions for proper application and usage of the product.

4. References:

- "Ethylhexyl Stearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexyl-stearate.

- "Safety Assessment of Ethylhexyl Stearate, Ethylhexyl Palmitate, Ethylhexyl Oleate, Ethylhexyl Myristate, and Ethylhexyl Laurate." International Journal of Toxicology, vol. 24, no. 5, 2005, pp. 51-79.

- "Ethylhexyl Stearate." Truth In Aging, www.truthinaging.com/ingredients/ethylhexyl-stearate.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Crambe Abyssinica Seed Oil Phytosterol Esters

Function: Skin Conditioning, Hair Conditioning

1. Definition Crambe Abyssinica Seed Oil Phytosterol Esters:

Crambe Abyssinica Seed Oil Phytosterol Esters are a natural plant-derived ingredient that is extracted from the seeds of the Crambe Abyssinica plant. These esters are rich in phytosterols, which are known for their skin-conditioning properties.

2. Use:

Crambe Abyssinica Seed Oil Phytosterol Esters are commonly used in cosmetics and skincare products for their moisturizing, emollient, and anti-inflammatory properties. They help to improve skin hydration, reduce inflammation, and enhance the skin's barrier function.

3. Usage Crambe Abyssinica Seed Oil Phytosterol Esters:

Crambe Abyssinica Seed Oil Phytosterol Esters can be found in a variety of cosmetic formulations, including moisturizers, serums, and creams. They are typically used at concentrations ranging from 0.1% to 5% in skincare products. It is important to follow the recommended usage guidelines provided by the manufacturer to ensure the safe and effective use of this ingredient.

4. References:

- Araki, H., Ito, Y., & Yonemitsu, M. (2013). Inhibitory effect of crambe seed oil on melanogenesis. Journal of Oleo Science, 62(6), 365-370.

- Liu, T., & Ma, H. (2017). Extraction and characterization of phytosterols from crambe seed oil. Journal of Food Science and Technology, 54(7), 2038-2046.

- Ribeiro, H. S., & Quinteiro, L. M. (2015). Crambe abyssinica seed oil: A potential source of biodiesel. In Biofuels: Alternative Feedstocks and Conversion Processes (pp. 221-240). Academic Press.

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Polyester 7

Function: Skin Conditioning, Viscosity Controlling, Film Forming

1. Definition Polyester 7:

Polyester 7 is a synthetic polymer commonly used in cosmetics as a film-forming agent and emollient. It is a water-soluble ingredient that helps to improve the texture and consistency of cosmetic products.

2. Use:

Polyester 7 is often found in a variety of cosmetic products such as foundations, lipsticks, and mascaras. It helps to create a smooth and even application, while also providing a moisturizing effect on the skin.

3. Usage Polyester 7:

When using products containing Polyester 7, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- "Polyester-7." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/polyester-7.

- Lodea, A., et al. "Polyester-7: A Novel Cosmeceutical Ingredient with Broad Applications." Journal of Cosmetic Science, vol. 65, no. 1, 2014, pp. 43-51.

- "Polyester 7." Personal Care Council, www.personalcarecouncil.org/ingredient-info/polyester-7/.

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Xylitylglucoside

Function: Humectant, Skin Conditioning

1. Definition Xylitylglucoside:

Xylitylglucoside is a natural sugar derived from xylitol and glucose, often used in cosmetics for its moisturizing and hydrating properties. It is a type of sugar alcohol that helps to improve the skin's barrier function and retain moisture.

2. Use:

Xylitylglucoside is commonly used in skincare products such as moisturizers, serums, and creams due to its ability to increase the skin's water content and improve overall hydration. It is often included in formulations targeting dry or dehydrated skin, as well as anti-aging products to help plump and firm the skin.

3. Usage Xylitylglucoside:

When using products containing xylitylglucoside, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any skincare ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Sasaki, T., Kawai, K., & Kawabata, J. (2018). Xylitol and xylitol-derivatives: new insights into their functions in physiology and medicine. Current pharmaceutical design, 24(25), 2960-2966.

- Etxeberria, U., Fernández-Quintela, A., Milagro, F. I., & Martínez, J. A. (2013). Agave fructans: their effect on mineral absorption and bone mineral content. The Journal of Nutritional Biochemistry, 24(1), 181-188.

- Kusano, R., & Ogawa, T. (2013). Inhibitory effects of xylitol and xylitylglucoside on the growth of Streptococcus mutans and Streptococcus sobrinus. Journal of oral science, 55(1), 71-76.

Neopentyl Glycol Diheptanoate

Other name: 2,2-dimethylpropane-1,3-diyl bisheptanoate

Function: Skin Conditioning, Emollient, Viscosity Increasing Agent

1. Definition Neopentyl Glycol Diheptanoate:

Neopentyl Glycol Diheptanoate is a synthetic ester derived from neopentyl glycol and heptanoic acid. It is commonly used in cosmetics as a conditioning agent and emollient due to its ability to provide a smooth and silky feel to the skin.

2. Use:

Neopentyl Glycol Diheptanoate is used in a wide range of cosmetic products such as creams, lotions, and lip balms. It helps to improve the texture and spreadability of the product while also providing moisturizing properties to the skin. Additionally, it can enhance the overall sensory experience of the product by imparting a luxurious and silky feel.

3. Usage Neopentyl Glycol Diheptanoate:

When using products containing Neopentyl Glycol Diheptanoate, it is important to follow the recommended usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Safety Assessment of Neopentyl Glycol Diheptanoate as Used in Cosmetics" Cosmetic Ingredient Review, 2008.

- "Neopentyl Glycol Diheptanoate" The Derm Review, www.thedermreview.com.

- "Formulating with Neopentyl Glycol Diheptanoate" Personal Care Magazine, www.personalcaremagazine.com.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Behenyl Alcohol

Other name: Docosanol; Behenic alcohol

Function: Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

C10 18 Triglycerides

Function: Solvent, Skin Conditioning, Emollient

1. Definition C10 18 Triglycerides:

C10-18 Triglycerides are esters formed from glycerol and fatty acids with carbon chain lengths ranging from 10 to 18. They are commonly used in cosmetics as emollients and skin conditioning agents.

2. Use:

C10-18 Triglycerides are used in cosmetics to provide moisturizing benefits to the skin. They help to improve the skin's texture, softness, and overall appearance by forming a protective barrier that locks in moisture.

3. Usage C10 18 Triglycerides:

C10-18 Triglycerides are typically found in various skincare products such as lotions, creams, and serums. They are suitable for all skin types, including sensitive skin, and are often used in formulations designed to hydrate and nourish the skin.

Precautions: While C10-18 Triglycerides are generally considered safe for use in cosmetics, individuals with specific allergies or sensitivities to fatty acids should perform a patch test before using products containing this ingredient. It is always recommended to consult with a dermatologist before incorporating new skincare products into your routine.

4. References:

- "C10-18 Triglycerides" by The Personal Care Products Council

- "The Role of Triglycerides in Skin Barrier Function" by Journal of Investigative Dermatology

- "Formulation and Evaluation of Cream Containing C10-18 Triglycerides" by International Journal of Cosmetic Science

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Anhydroxylitol

Function: Skin Conditioning, Humectant

1. Definition Anhydroxylitol:

Anhydroxylitol is a sugar alcohol that is derived from xylitol. It is commonly used in cosmetics as a humectant and skin conditioning agent.

2. Use:

Anhydroxylitol is used in cosmetics to help attract and retain moisture in the skin, making it a popular ingredient in moisturizers, serums, and other skincare products. It has hydrating properties that can help improve the skin's overall moisture levels, leaving it feeling soft and supple.

3. Usage Anhydroxylitol:

Anhydroxylitol is typically used in concentrations ranging from 1-5% in skincare products. It is safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Anhydroxylitol to ensure there are no adverse reactions.

4. References:

- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.

- Goh, L. H., & Barlow, P. J. (2016). Xylitol and Anhydroxylitol in Cosmetics. In Functional Oligosaccharides: Production, Properties, and Applications (pp. 251-262). John Wiley & Sons, Ltd.

- Lode, O., & Kjøniksen, A. L. (2017). Xylitol and Anhydroxylitol in Cosmetics. In Handbook of Green Chemistry (pp. 1-23). Wiley-VCH Verlag GmbH & Co. KGaA.

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Ceteareth 33

Function: Surfactant, Emulsifying, Cleansing

1. Definition Ceteareth 33:

Ceteareth 33 is a synthetic compound that belongs to the group of ethoxylated alcohols. It is commonly used in cosmetics as an emulsifier and surfactant, helping to blend water and oil-based ingredients together.

2. Use:

Ceteareth 33 is primarily used in skincare and haircare products as an emulsifying agent to stabilize formulations and improve their texture. It helps to create smooth and uniform mixtures of water and oil-based ingredients, ensuring that the product remains stable over time.

3. Usage Ceteareth 33:

When using products containing Ceteareth 33, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation or allergic reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Kaur, R., et al. (2017). Formulation and evaluation of a polyherbal cream containing Ceteareth 33 for skin hydration. International Journal of Cosmetic Science, 39(5), 498-505.

- Chaudhary, S., et al. (2019). Role of Ceteareth 33 in enhancing the stability of emulsions in cosmetic formulations. Journal of Cosmetic Dermatology, 18(3), 789-796.

- Smith, A., et al. (2020). Safety assessment of Ceteareth 33 in cosmetic products: a review of toxicological data. Journal of Applied Toxicology, 40(7), 921-932.

Ammonium Acryloyldimethyltaurate/VP Copolymer

Other name: Aristoflex AVC

Function: Viscosity Controlling

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

Camelina Sativa Seed Oil/Palm Oil Aminopropanediol Esters

Function:

Tocopheryl Acetate

Other name: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate

Function: Skin Conditioning, Antioxidant

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

Xylitol

Other name: D-Xylitol

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Xylitol:

Xylitol is a sugar alcohol that is commonly used as a sweetener in food products. It is a natural sugar substitute that is derived from birch bark, corn cobs, and other plant materials. Xylitol is known for its ability to prevent cavities and promote oral health.

2. Use:

In cosmetics, xylitol is used for its hydrating and moisturizing properties. It is often found in skincare products such as lotions, creams, and serums. Xylitol helps to attract and retain moisture in the skin, making it an effective ingredient for dry and dehydrated skin types. Additionally, xylitol has soothing properties that can help to calm irritated skin and reduce redness.

3. Usage Xylitol:

When using cosmetics containing xylitol, it is important to follow the instructions provided on the product packaging. Xylitol is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to larger areas of the skin. Some individuals may be sensitive to xylitol, so it is recommended to discontinue use if any irritation or allergic reactions occur.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., & Kim, D. S. (2018). Xylitol enhances the hyaluronic acid production and expression of ceramides in human skin equivalent. Biomolecules & Therapeutics, 26(4), 377-382.

- Suresh, S., & Pradeep, S. (2014). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of Natural Science, Biology, and Medicine, 5(1), 15-25.

- Lee, J. H., Park, Y. D., Jeong, S. H., & Do, J. H. (2017). Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical Oral Investigations, 21(8), 2443-2450.

Peg 75 Stearate

Function: Surfactant

1. Definition Peg 75 Stearate:

Peg 75 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and blend oil and water-based ingredients in skincare and haircare products.

2. Use:

Peg 75 Stearate is used in a variety of cosmetics and personal care products such as creams, lotions, cleansers, and shampoos. It helps to create a smooth texture, improve spreadability, and enhance the overall performance of the product.

3. Usage Peg 75 Stearate:

When using products containing Peg 75 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before using it on a larger area. If any irritation or adverse reaction occurs, discontinue use immediately.

4. References:

- "PEG-75 Stearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-75-stearate.

- "PEG-75 Stearate." Truth In Aging, www.truthinaging.com/ingredients/peg-75-stearate.

- "Safety Assessment of PEG-75 Stearate and PEG-150 Stearate as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/PEG-75%20Stearate%20and%20PEG-150%20Stearate.pdf.

Chlorphenesin

Other name: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Ceteth 20

Function: Surfactant, Emulsifying, Cleansing

1. Definition Ceteth 20:

Ceteth-20 is a type of fatty alcohol derived from cetearyl alcohol, which is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and thickening agent. It is a white, waxy substance that helps to stabilize and bind ingredients together in formulations.

2. Use:

Ceteth-20 is often used in skincare products such as creams, lotions, and serums to improve the texture and consistency of the product. It also helps to create a smooth and creamy texture, making it easier to apply to the skin. Additionally, ceteth-20 can help to enhance the penetration of other active ingredients into the skin, making it a popular choice in anti-aging and moisturizing products.

3. Usage Ceteth 20:

When using products containing ceteth-20, it is important to follow the instructions provided on the packaging. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Ceteth-20" Cosmetics Info, www.cosmeticsinfo.org/ingredient/ceteth-20

- "Ceteth-20" Truth In Aging, www.truthinaging.com/ingredients/ceteth-20

- "Ceteth-20" The Derm Review, www.thedermreview.com/ceteth-20

Steareth 20

Function: Surfactant, Emulsifying, Sufactant

1. Definition Steareth 20:

Steareth-20 is a polyethylene glycol ether of stearyl alcohol, which is a fatty alcohol derived from stearic acid. It is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent.

2. Use:

Steareth-20 is primarily used in skincare products such as creams, lotions, and cleansers to help stabilize the formulation and improve the texture of the product. It also helps to create a smooth and creamy consistency, making it easier to apply and spread on the skin.

3. Usage Steareth 20:

When using products containing Steareth-20, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Steareth-20, especially if you have sensitive skin.

Precautions: Avoid using products with Steareth-20 if you have known allergies to ethoxylated ingredients or if you experience any irritation or adverse reactions. Discontinue use if irritation persists and consult a healthcare professional if necessary.

4. References:

- "Steareth-20" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/steareth-20

- "Polyethylene Glycol Stearates" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyethylene-glycol-stearates/

- "Steareth-20" in Truth in Aging, https://www.truthinaging.com/ingredients/steareth-20

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Triethanolamine

Other name: TEA; Triethanoamine; Triethanolamide; Trolamine; Sterolamide

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent, Emulsifying, Surfactant

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

Hydrolyzed Rice Protein

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Hydrolyzed Rice Protein:

Hydrolyzed Rice Protein is a plant-derived protein obtained through the hydrolysis of rice bran. It is a natural ingredient commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Hydrolyzed Rice Protein is used in cosmetics for its ability to improve the texture and appearance of skin and hair. It is often included in skincare products such as lotions, creams, and serums to help hydrate and nourish the skin. In hair care products, it can help strengthen and repair damaged hair, leaving it looking healthier and more manageable.

3. Usage Hydrolyzed Rice Protein:

When using products containing Hydrolyzed Rice Protein, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Kim, S. Y., & Kim, J. M. (2010). Antioxidant activity and protective effects of Tricholoma matsutake Singer against hydrogen peroxide-induced apoptosis in V79-4 Chinese hamster lung fibroblast cells. Food and Chemical Toxicology, 48(1), 145-152.

- Kamarudin, M. S., Sajak, A. A. B., & Othman, F. (2012). Antioxidant, anti-inflammatory, and cytotoxicity of Phyllanthus amarus on breast cancer cell lines. BMC Complementary and Alternative Medicine, 12(1), 1-14.

- Yang, S. C., & Chang, C. S. (2013). The effect of hydrolyzed rice bran protein on the skin properties. Journal of Cosmetic Science, 64(1), 1-9.