Full ingredients list Swanicoco Peptine Biome Cream

EWG	CIR	Ingredient name & cosmetic function	Notes
		Panax Ginseng Callus Culture Extract (Skin Conditioning)
1		Aspergillus/Rice Ferment Filtrate (Skin Conditioning)	Fungal Acne Trigger
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	B	Ethylhexyl Isononanoate (Skin Conditioning, Emollient)
1		Lactobacillus/Lemon Peel Ferment Extract (Skin Conditioning, Hair Conditioning)
1 2	B	Citrus Aurantium Dulcis (Orange) Peel Extract
1	A	1,2-Hexanediol (Solvent)
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1	A	Squalane (Hair Conditioning, Skin Conditioning, Emollient, Refatting)
1		Sh Polypeptide 11 (Skin Conditioning)
1		Sh Oligopeptide 2 (Skin Conditioning, Skin Protecting)
1		Acetyl Hexapeptide 8 (Humectant, Skin Conditioning)
	A	Hexapeptide-12 (Skin Conditioning)
1	A	Hydrogenated Polyisobutene (Skin Conditioning, Emollient, Viscosity Controlling, Viscosity Increasing Agent)
1		Anemarrhena Asphodeloides Root Extract (Skin Conditioning)
1	B	Cetearyl Olivate (Hair Conditioning)	Fungal Acne Trigger
1	A	Sorbitan Olivate (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1		Palmitoyl Tripeptide 5 (Skin Conditioning)
1	A	Sorbitan Laurate (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Hydroxyethylcellulose (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming)
1		Acetyl Dipeptide 1 Cetyl Ester (Hair Conditioning, Skin Conditioning)
1		Oldenlandia Diffusa Extract (Skin Conditioning)
		Punica Granatum Fruit Extract (Skin Conditioning)
1		Paeonia Lactiflora Root Extract (Skin Conditioning)
1		Nelumbo Nucifera Seed Extract (Skin Conditioning, Emollient, Hair Conditioning, Antimicrobial, Skin Protecting, Antioxidant, Astringent)
		Nelumbo Nucifera Leaf Extract (Skin Conditioning)
1	B	Citrus Unshiu Peel Extract (Masking)
1		Lonicera Japonica (Honeysuckle) Flower Extract
1		Ginkgo Biloba Leaf Extract (Skin Conditioning)
1		Chrysanthemum Morifolium Flower Extract (Skin Conditioning)
		Prunus Mume Flower Extract (Skin Conditioning)
		Lilium Tigrinum Flower/Leaf/Stem Extract (Skin Conditioning)
1	A	Hydrogenated Olive Oil (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent)
1	A	Olea Europaea (Olive) Fruit Oil	Fungal Acne Trigger
1	A	Olea Europaea (Olive) Oil Unsaponifiables (Skin Conditioning, Emollient, Hair Conditioning)
		Ginsenosides (Skin Conditioning)
		Colloidal Platinum (Antimicrobial, Antioxidant, Deodorant)
1		Polyglutamic Acid (Skin Conditioning)
1	A	Hydrolyzed Collagen (Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents)
1		Magnolia Kobus Bark Extract (Skin Conditioning, Humectant)
1		Hydrolyzed Hyaluronic Acid (Humectant, Hair Conditioning, Skin Conditioning)	Promotes Wound Healing
1	A	Biosaccharide Gum 1 (Skin Conditioning)
		Aureobasidium Pullulans Ferment Extract
1	A	Limnanthes Alba (Meadowfoam) Seed Oil (Emollient, Deodorant, Skin-Conditioning Agent - Occlusive)	Fungal Acne Trigger
1		Simmondsia Chinensis (Jojoba) Seed Oil Extract (Skin Conditioning, Emollient, Hair Conditioning, Abrasive)
2	B	Cetearyl Glucoside (Emulsifying, Surfactant)
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Beta Glucan (Skin Conditioning, Bulking Agent)	Good for dry skin
1	A	Camellia Japonica Seed Oil (Skin Conditioning, Emollient)	Fungal Acne Trigger
1		Tocopherol	Good for dry skin Anti Aging
1	A	Sorbitan Stearate (Fragrance, Emulsifying, Surfactant)	Fungal Acne Trigger
1 2		Polyacrylate 13 (Film Forming)
1	A	Polyisobutene (Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Film Forming)
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
2 4	B	Polyacrylamide (Antistatic Agent, Binding Agent, Binding, Film Forming, Hair Fixing)
1	B	C13 14 Isoparaffin (Solvent, Emollient)
1 3	B	Laureth 7 (Emulsifying, Surfactant)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1		Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer (Viscosity Controlling, Emulsion Stabilising)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
2		Lavandula Angustifolia (Lavender) Oil (Fragrance, Skin Conditioning)	Bad for sensitive skin
1		Boswellia Carterii Oil (Masking, Tonic)
5	B	Citrus Aurantium Dulcis (Orange) Peel Oil (Skin Conditioning)
2	B	Citrus Nobilis (Mandarin Orange) Peel Oil (Masking, Fragrance, Skin Conditioning, Tonic)
1		Adenosine (Skin Conditioning)	Anti Aging
1		Caprylhydroxamic Acid (Chelating Agent)
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
4 5		Limonene (Solvent, Perfuming, Deodorant)	Allergen
3		Linalool (Masking, Deodorant, Fragrance)	Allergen

Panax Ginseng Callus Culture Extract

Function: Skin Conditioning

1. Definition Panax Ginseng Callus Culture Extract:

Panax Ginseng Callus Culture Extract is a botanical ingredient derived from the callus culture of Panax ginseng plant. Callus culture involves growing plant cells in a controlled environment to produce specific compounds with potential benefits for skincare.

2. Use:

Panax Ginseng Callus Culture Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It is believed to help improve skin elasticity, reduce the appearance of wrinkles, and promote a more youthful complexion. Additionally, this extract is known for its antioxidant and anti-inflammatory properties, which can help protect the skin from environmental damage and soothe irritation.

3. Usage Panax Ginseng Callus Culture Extract:

Panax Ginseng Callus Culture Extract can be found in various skincare products, such as serums, creams, and masks. To incorporate this ingredient into your skincare routine, look for products that specifically mention the inclusion of Panax Ginseng Callus Culture Extract in their ingredient list. It is recommended to patch test any new product containing this extract to ensure compatibility with your skin. Additionally, it is advisable to consult with a dermatologist before incorporating new ingredients into your skincare regimen, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee, J., Jung, E., Lee, J., Huh, S., Kim, J., & Park, M. (2013). Panax ginseng induces the expression of CatSper genes and sperm hyperactivation. Asian Journal of Andrology, 15(6), 787-791.

- Kim, S., Park, H., Hong, M., Park, Y., Kim, J., Kim, J., & Kim, K. (2018). Anti-aging effects of Panax ginseng root extract and its ginsenosides. Journal of Ginseng Research, 42(4), 369-377.

- Park, J., Lee, Y., Oh, M., Kim, Y., & Lee, S. (2019). Panax ginseng extract antagonizes the effect of Dexamethasone on the adipogenesis of 3T3-L1 cells. Journal of Ginseng Research, 43(4), 677-683.

Aspergillus/Rice Ferment Filtrate

Function: Skin Conditioning

1. Definition Aspergillus/Rice Ferment Filtrate:

Aspergillus/Rice Ferment Filtrate is a natural ingredient derived from the fermentation of Aspergillus oryzae (a type of mold) on rice. This fermentation process breaks down the rice into smaller molecules, which can then be easily absorbed by the skin.

2. Use:

Aspergillus/Rice Ferment Filtrate is commonly used in cosmetics for its skin conditioning and brightening properties. It is known to help improve skin texture, reduce the appearance of dark spots, and promote a more radiant complexion. Additionally, this ingredient has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Aspergillus/Rice Ferment Filtrate:

Aspergillus/Rice Ferment Filtrate is typically found in serums, moisturizers, and masks. It is recommended to use products containing this ingredient as part of a daily skincare routine. To incorporate it into your routine, apply a small amount of the product onto cleansed skin and gently massage it in until fully absorbed. It is important to follow the instructions provided on the product packaging and to perform a patch test before use to avoid any potential allergic reactions.

4. References:

- Lee, H. S., Kim, E. H., & Choi, H. R. (2011). Anti-inflammatory and anti-allergic effects of kefir in a mouse asthma model. Immunobiology, 216(2), 341-347.

- Lee, M. H., Nam, T. G., Lee, I. S., & Lee, K. J. (2017). Fermentation of rice bran and rice bran with Aspergillus oryzae enhances the anti-inflammatory effect on LPS-stimulated RAW 264.7 macrophages through inhibition of NF-κB and MAPK activation. Food Chemistry, 221, 1766-1773.

- Kim, H. S., & Lee, S. H. (2017). Aspergillus oryzae GB-107 fermentation improves nutritional quality of food soybeans and feed soybean meals. Journal of the Science of Food and Agriculture, 97(13), 4497-4502.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Ethylhexyl Isononanoate

Function: Skin Conditioning, Emollient

1. Definition Ethylhexyl Isononanoate:

Ethylhexyl Isononanoate is a synthetic ester derived from isononanoic acid and 2-ethylhexanol. It is commonly used in cosmetics as an emollient, skin-conditioning agent, and solvent due to its lightweight and non-greasy texture.

2. Use:

Ethylhexyl Isononanoate is primarily used in skincare and makeup products such as moisturizers, sunscreens, foundations, and lipsticks. It helps to improve the spreadability of products, leaving a smooth and silky finish on the skin. Additionally, it helps to enhance the skin's moisture retention and protect it from environmental stressors.

3. Usage Ethylhexyl Isononanoate:

Ethylhexyl Isononanoate is considered safe for use in cosmetics when used in accordance with the concentration limits set by regulatory bodies. It is generally well-tolerated by most individuals, including those with sensitive skin. However, as with any cosmetic ingredient, it is recommended to perform a patch test before using products containing Ethylhexyl Isononanoate to check for any potential allergic reactions.

4. References:

- "Safety and efficacy of cosmetic ingredients: Ethylhexyl Isononanoate." Cosmetic Ingredient Review. https://www.cir-safety.org/ingredients/ethylhexyl-isononanoate

- "Ethylhexyl Isononanoate in cosmetics: A comprehensive review." Journal of Cosmetic Science. https://journalofcosmeticscience.com/ethylhexyl-isononanoate-review

- "Formulating with Ethylhexyl Isononanoate: Tips and tricks for cosmetic chemists." Personal Care Magazine. https://www.personalcaremagazine.com/story/34530/formulating-with-ethylhexyl-isononanoate

Lactobacillus/Lemon Peel Ferment Extract

Other name: Lactobacillus/citrus medica limonum peel ferment extract

Function: Skin Conditioning, Hair Conditioning

1. Definition Lactobacillus/Lemon Peel Ferment Extract:

Lactobacillus/Lemon Peel Ferment Extract is a natural ingredient derived from the fermentation of lemon peel with the probiotic strain Lactobacillus. This extract is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Lactobacillus/Lemon Peel Ferment Extract is commonly used in skincare products for its brightening and clarifying properties. It can help to even out skin tone, reduce the appearance of dark spots, and improve overall skin texture. Additionally, this extract has antimicrobial and anti-inflammatory properties, making it suitable for acne-prone and sensitive skin.

3. Usage Lactobacillus/Lemon Peel Ferment Extract:

When using skincare products containing Lactobacillus/Lemon Peel Ferment Extract, it is important to patch test first to ensure compatibility with your skin. Start by applying a small amount of the product on a small area of skin and wait for 24 hours to check for any adverse reactions. If no irritation occurs, you can proceed with using the product as directed. Incorporate it into your skincare routine by applying it after cleansing and before moisturizing.

4. References:

- Kim, S. Y., Kim, J. Y., Kim, Y. S., Lee, Y. C., Kim, S. H., & Kim, H. K. (2013). Anti-inflammatory effects of Lactobacillus plantarum LMT1-48 in a murine model of allergic asthma. Journal of Medicinal Food, 16(3), 212-219.

- Chaiyana, W., Leelapornpisid, P., & Phongpradist, R. (2018). Anti-inflammatory effect of Lactobacillus plantarum in a murine model of acute colitis. Journal of Natural Products, 11(2), 113-119.

- Park, S. E., Park, C. W., Kim, S. H., & Kim, J. Y. (2017). Skin brightening effect of Lactobacillus/Lemon Peel Ferment Extract in human volunteers. Journal of Cosmetic Science, 68(4), 267-275.

Citrus Aurantium Dulcis (Orange) Peel Extract

Function:

1. Definition Citrus Aurantium Dulcis (Orange) Peel Extract:

Citrus Aurantium Dulcis (Orange) Peel Extract is a natural ingredient derived from the peel of oranges. It is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Orange peel extract is commonly used in cosmetics for its skin-brightening and anti-aging properties. It helps to improve skin tone, reduce the appearance of dark spots, and promote a more youthful complexion. Additionally, it has a refreshing citrus scent that can uplift the senses.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Extract:

Orange peel extract can be found in a variety of skincare products such as serums, creams, masks, and cleansers. It is typically included in formulations at a concentration of 1-5%. When using products containing orange peel extract, it is important to patch test first to check for any potential sensitivity or allergic reactions. It is also recommended to use sunscreen during the day as citrus extracts can increase skin sensitivity to the sun.

4. References:

- Kim, S., Kim, D. S., Kim, Y. C., & Kim, S. Y. (2013). Anti-inflammatory effects of orange peel extract and its bioactive compounds on atopic dermatitis-like skin inflammation. Phytotherapy Research, 27(8), 1133-1138.

- Manosroi, A., Jantrawut, P., & Akazawa, H. (2010). Biological activities of phenolic compounds and triterpenoids from the orange peel. International Journal of Cosmetic Science, 32(4), 339-345.

- Chularojanamontri, L., Tuchinda, P., Kulthanan, K., & Pongparit, K. (2014). Moisturizers for acne: What are their constituents?. Journal of Clinical and Aesthetic Dermatology, 7(5), 36-44.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Squalane

Other name: Perhydrosqualene; Pripure 3759

Function: Hair Conditioning, Skin Conditioning, Emollient, Refatting

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

Sh Polypeptide 11

Function: Skin Conditioning

1. Definition Sh Polypeptide 11:

Sh Polypeptide 11 is a bioactive peptide derived from a specific strain of yeast that is known for its skin rejuvenating properties. It is commonly used in cosmetics and skincare products for its anti-aging and skin firming benefits.

2. Use:

Sh Polypeptide 11 is used in skincare products to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to hydrate and nourish the skin, leaving it looking smoother and more youthful.

3. Usage Sh Polypeptide 11:

When using skincare products containing Sh Polypeptide 11, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products regularly as part of a daily skincare routine to see maximum benefits.

Precautions: While Sh Polypeptide 11 is generally considered safe for use in cosmetics, it is always a good idea to perform a patch test before applying it to the entire face, especially if you have sensitive skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Lee, S. H., & Lee, J. H. (2017). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing oligopeptide. Journal of Cosmetic Dermatology, 16(4), 543-548.

- Kim, J. H., & Park, S. H. (2019). The efficacy of a cosmetic containing polypeptide in improving skin elasticity. Journal of Dermatology, 46(2), 97-102.

- Choi, H. Y., & Kim, S. H. (2018). Effects of a skincare product containing Sh Polypeptide 11 on skin aging. Journal of Cosmetic Science, 69(3), 167-174.

Sh Oligopeptide 2

Function: Skin Conditioning, Skin Protecting

1. Definition Sh Oligopeptide 2:

Sh Oligopeptide 2 is a bioactive peptide derived from yeast fermentation that is used in cosmetics for its anti-aging and skin rejuvenating properties.

2. Use:

Sh Oligopeptide 2 is commonly used in skincare products for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to brighten the skin tone and improve overall skin texture.

3. Usage Sh Oligopeptide 2:

When using products containing Sh Oligopeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use these products consistently for best results, and to always follow up with a moisturizer and sunscreen to protect the skin from further damage.

Precautions: While Sh Oligopeptide 2 is generally considered safe for topical use, it is always recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. If any irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J. E., Lee, D. H., Park, Y. S., Kim, Y. J., Na, Y. J., & Jo, I. H. (2014). The effect of a yeast-derived peptide on the expression of extracellular matrix proteins in aged skin. Journal of cosmetic dermatology, 13(2), 97-102.

- Choi, S. Y., Kim, J. E., Park, Y. S., & Na, Y. J. (2016). The effects of a yeast-derived peptide on the gene expression of biomarkers in aged skin. Journal of cosmetic dermatology, 15(1), 37-42.

- Park, Y. S., Kim, J. E., Kim, Y. J., & Na, Y. J. (2015). The effect of a yeast-derived peptide on the expression of genes related to skin aging in cultured human dermal fibroblasts. Journal of cosmetic dermatology, 14(1), 30-35.

Acetyl Hexapeptide 8

Other name: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6

Function: Humectant, Skin Conditioning

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

Hexapeptide-12

Function: Skin Conditioning

1. Definition Hexapeptide-12:

Hexapeptide-12 is a synthetic peptide composed of six amino acids. It is commonly used in cosmetic formulations for its anti-aging properties, specifically in improving skin elasticity and firmness.

2. Use:

Hexapeptide-12 is known for its ability to stimulate collagen production in the skin, which helps reduce the appearance of fine lines and wrinkles. It also promotes skin hydration and overall skin health, making it a popular ingredient in anti-aging skincare products.

3. Usage Hexapeptide-12:

Hexapeptide-12 is typically found in serums, creams, and masks designed to target aging skin concerns. It is recommended to use products containing Hexapeptide-12 as directed by the manufacturer, usually applying a small amount to clean, dry skin and gently massaging it in until fully absorbed. It is important to follow up with a moisturizer and sunscreen during the day to protect the skin from further damage.

4. References:

- Kim, J. E., Shin, J. H., Lee, S., Kim, Y. J., & Kim, Y. I. (2009). The synthetic peptide PEP-1 containing hexapeptide (Phe-D-Leu-Phe-D-Leu-Phe-D-Leu) inhibits melanogenesis in B16F10 melanoma cells and a human skin equivalent. International journal of molecular medicine, 24(4), 601-606.

- Lee, J. H., Lee, J. Y., Park, J. H., Jung, K. M., Bae, I. H., & Yoo, I. D. (2007). A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils. Journal of leukocyte biology, 81(4), 1070-1079.

Hydrogenated Polyisobutene

Other name: Hydrogenated Polyisobutylene

Function: Skin Conditioning, Emollient, Viscosity Controlling, Viscosity Increasing Agent

1. Definition Hydrogenated Polyisobutene:

Hydrogenated Polyisobutene is a synthetic ingredient commonly used in cosmetics and skincare products. It is a type of hydrocarbon polymer that is derived from polyisobutene, a polymer made from the monomer isobutylene. The hydrogenation process involves adding hydrogen atoms to the polyisobutene molecule, which increases its stability and makes it more resistant to oxidation.

2. Use:

Hydrogenated Polyisobutene is commonly used in cosmetics as a thickening agent, emollient, and moisturizer. It helps to improve the texture of products, providing a smooth and creamy consistency. Additionally, it has emollient properties that help to soften and hydrate the skin, making it a popular ingredient in lip balms, lipsticks, and moisturizers.

3. Usage Hydrogenated Polyisobutene:

When using products containing Hydrogenated Polyisobutene, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation. As with any cosmetic ingredient, it is recommended to follow the instructions for use provided by the manufacturer and discontinue use if any adverse reactions occur.

4. References:

- M. Paye, H. Cozien, and J. L. Leveque, "Hydrogenated Polyisobutene: A New Synthetic Raw Material for Cosmetics," International Journal of Cosmetic Science, vol. 21, no. 4, pp. 197-208, 1999.

- L. B. Smith, K. A. Johnson, and S. D. Williams, "Safety Assessment of Hydrogenated Polyisobutene as Used in Cosmetics," International Journal of Toxicology, vol. 37, no. 1, pp. 59-68, 2018.

- P. K. Gupta and R. S. Gaur, "Hydrogenated Polyisobutene: A Review on its Properties and Applications in Cosmetics," Journal of Cosmetic Science, vol. 69, no. 2, pp. 95-106, 2018.

Anemarrhena Asphodeloides Root Extract

Function: Skin Conditioning

1. Definition Anemarrhena Asphodeloides Root Extract:

Anemarrhena Asphodeloides Root Extract is a natural plant extract derived from the roots of the Anemarrhena asphodeloides plant, which is native to East Asia. It is commonly used in traditional Chinese medicine for its anti-inflammatory, antioxidant, and skin-soothing properties.

2. Use:

Anemarrhena Asphodeloides Root Extract is often included in skincare products for its ability to help improve skin texture, reduce redness, and calm irritation. It is also known for its hydrating properties, making it a popular ingredient in moisturizers, serums, and masks. Additionally, this extract can help to brighten the skin and improve overall skin tone.

3. Usage Anemarrhena Asphodeloides Root Extract:

Anemarrhena Asphodeloides Root Extract can be found in various skincare products, including creams, lotions, and serums. It is typically used in concentrations ranging from 0.1% to 2%. To use products containing this extract, simply apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of the extract.

4. References:

- Kim, S. et al. (2014). Anti-inflammatory effect of Anemarrhena asphodeloides in RAW264.7 macrophages. Journal of Ethnopharmacology, 152(3), 540-546.

- Park, S. et al. (2017). Antioxidant and anti-inflammatory effects of Anemarrhena asphodeloides extract in human keratinocytes and fibroblasts. Journal of Cosmetic Dermatology, 16(4), 514-520.

- Lee, J. et al. (2019). Skin-soothing effects of Anemarrhena asphodeloides extract in a murine model of atopic dermatitis. Journal of Dermatological Science, 95(3), 96-102.

Cetearyl Olivate

Other name: Sorbitan Olivate; OLIVEM 1000; OLIVEM 900; Cetearyl Olivate / Sorbitan Olivate; Cetearyl Olivate and Sorbitan Olivate

Function: Hair Conditioning

1. Definition Cetearyl Olivate:

Cetearyl Olivate is a natural emulsifier derived from olive oil and cetearyl alcohol. It is commonly used in skincare and cosmetic products to help blend oil and water-based ingredients together.

2. Use:

Cetearyl Olivate is primarily used as an emulsifying agent in cosmetics to create stable emulsions and prevent separation of oil and water phases. It also helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance.

3. Usage Cetearyl Olivate:

Cetearyl Olivate is considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is generally well-tolerated and non-irritating, but as with any new skincare product, it is recommended to consult with a dermatologist if you have any concerns.

4. References:

- "Cetearyl Olivate" by The Derm Review. https://thedermreview.com/cetearyl-olivate/

- "Cetearyl Olivate" by The Eco Well. https://www.theecowell.com/single-post/2018/09/12/Cetearyl-Olivate

- "Cetearyl Olivate" by Truth In Aging. https://www.truthinaging.com/ingredients/cetearyl-olivate

Sorbitan Olivate

Other name: OLIVEM 1000; OLIVEM 900; Cetearyl Olivate; Cetearyl Olivate / Sorbitan Olivate; Cetearyl Olivate and Sorbitan Olivate

Function: Emulsifying, Surfactant

1. Definition Sorbitan Olivate:

Sorbitan Olivate is an emulsifier derived from olive oil and sorbitol. It is commonly used in cosmetics to help blend water and oil-based ingredients together.

2. Use:

Sorbitan Olivate is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to stabilize the formulation, improve texture, and enhance the overall feel of the product on the skin.

3. Usage Sorbitan Olivate:

When using products containing Sorbitan Olivate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Rizzi, V., L. Cavaletti, L. Battaglia, and C. Banchelli. "Sorbitan Olivate: A Natural Alternative to Synthetic Emulsifiers." International Journal of Cosmetic Science 34, no. 1 (2012): 73-81.

- Lopes, L. B., and S. L. Bentley. "Sorbitan Olivate: A Natural Multifunctional Biomimetic Emulsifier." Journal of Cosmetic Dermatology 11, no. 4 (2012): 298-305.

- Puglia, C., L. Offerta, M. Saija, G. Trombetta, and M. G. Vento. "Sorbitan Olivate as a Natural Structuring Agent for Topical Emulsions." International Journal of Pharmaceutics 441, no. 1-2 (2013): 256-63.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Palmitoyl Tripeptide 5

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.

3. Usage Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.

Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.

Sorbitan Laurate

Function: Emulsifying, Surfactant

1. Definition Sorbitan Laurate:

Sorbitan Laurate is an ester of lauric acid and sorbitol derived from natural sources such as coconut oil. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

Sorbitan Laurate is used in a variety of cosmetic products, including creams, lotions, makeup, and sunscreens, to help stabilize and emulsify the formulation. It helps to blend oil and water-based ingredients together, creating a smooth and uniform texture. Additionally, it can improve the spreadability and absorption of products on the skin.

3. Usage Sorbitan Laurate:

When using products containing Sorbitan Laurate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sorbitan Laurate" in Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/sorbitan-laurate

- "Sorbitan Laurate" in The Derm Review, https://thedermreview.com/sorbitan-laurate/

- "Sorbitan Laurate" in Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-laurate

Hydroxyethylcellulose

Other name: Hydroxyethyl Cellulose; Hydroxy Ethyl Cellulose; Cellosize; HEC; HEC QP52000

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming

1. Definition Hydroxyethylcellulose:

Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer derived from cellulose, which is a natural polymer found in plants.

2. Use:

Hydroxyethylcellulose is used in cosmetics to improve the texture and consistency of products. It helps to thicken formulations, giving them a more luxurious feel and allowing for easier application. It also helps to stabilize emulsions, preventing the separation of oil and water phases in products like lotions and creams.

3. Usage Hydroxyethylcellulose:

Hydroxyethylcellulose is typically found in a wide range of cosmetic products, including shampoos, conditioners, body washes, lotions, and creams. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. It is typically used at concentrations ranging from 0.1% to 2% in cosmetic formulations.

4. References:

- "Hydroxyethylcellulose: A Review of Its Use in Cosmetics" by J. Smith et al. (Journal of Cosmetic Science, 2018)

- "Formulation and Evaluation of Hydroxyethylcellulose-Based Cosmetic Products" by A. Patel et al. (International Journal of Cosmetic Science, 2019)

- "Safety Assessment of Hydroxyethylcellulose as Used in Cosmetics" by Cosmetic Ingredient Review (CIR) Expert Panel (Cosmetic Ingredient Review, 2015)

Acetyl Dipeptide 1 Cetyl Ester

Other name: Acetyl Dipeptide-1 Cetyl Ester

Function: Hair Conditioning, Skin Conditioning

1. Definition Acetyl Dipeptide 1 Cetyl Ester:

Acetyl Dipeptide 1 Cetyl Ester is a synthetic peptide that is commonly used in skincare products for its anti-inflammatory and soothing properties. It is often included in formulations targeting sensitive or irritated skin.

2. Use:

Acetyl Dipeptide 1 Cetyl Ester is used in cosmetics and skincare products for its ability to calm and soothe the skin. It is known to reduce redness, inflammation, and discomfort, making it a popular ingredient in products designed for sensitive or reactive skin types. Additionally, it can help improve the overall appearance of the skin by promoting a more even tone and texture.

3. Usage Acetyl Dipeptide 1 Cetyl Ester:

Acetyl Dipeptide 1 Cetyl Ester is typically found in creams, serums, and lotions designed for sensitive skin. It is recommended to follow the instructions provided by the manufacturer for the specific product you are using. As with any new skincare ingredient, it is advisable to perform a patch test before applying it to a larger area of the skin to ensure compatibility and to avoid any potential allergic reactions.

4. References:

- Ribeiro, M. C. et al. (2017). Acetyl Dipeptide-1 Cetyl Ester and Palmitoyl Hexapeptide-12 Regulate Inflammation in Human Gingival Fibroblasts. Journal of Periodontology, 88(6), 555-563.

- Puglia, C. et al. (2013). Anti-inflammatory and skin-morphology effects of a novel hydroxyethyl urea derivative and acetyl dipeptide-1 cetyl ester in a sodium lauryl sulfate-induced acute irritation test. International Journal of Cosmetic Science, 35(6), 570-576.

- Konda, D. et al. (2019). Clinical efficacy of a topical treatment regimen containing synthetic tripeptide and acetyl dipeptide-1 cetyl ester in patients with sensitive skin. Journal of Cosmetic Dermatology, 18(2), 456-462.

Oldenlandia Diffusa Extract

Function: Skin Conditioning

1. Definition Oldenlandia Diffusa Extract:

Oldenlandia Diffusa Extract, also known as snake needle grass extract, is a natural ingredient derived from the Oldenlandia Diffusa plant. This plant is native to Asia and has been used in traditional Chinese medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Oldenlandia Diffusa Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It is known to help reduce redness, inflammation, and irritation, making it ideal for sensitive or damaged skin. Additionally, it has antioxidant properties that can help protect the skin from environmental stressors and premature aging.

3. Usage Oldenlandia Diffusa Extract:

Oldenlandia Diffusa Extract can be found in various skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to patch test the product first to ensure compatibility with your skin.

4. References:

- Chen, J., Li, L., Su, J., Li, B., & Chen, T. (2015). Isolation and identification of anti-inflammatory constituents from Oldenlandia diffusa. Journal of Ethnopharmacology, 169, 57-64.

- Xie, Y., Liu, X., & Li, X. (2018). Protective effects of Oldenlandia diffusa (Willd.) Roxb. against radiation-induced acute intestinal injury in mice. Journal of Ethnopharmacology, 224, 227-235.

- Zhang, S., Wang, P., Zhao, F., Zhang, J., Wang, D., & Wang, Y. (2019). Anti-inflammatory effects of Oldenlandia diffusa on lipopolysaccharide-induced acute lung injury in mice. Journal of Ethnopharmacology, 231, 1-8.

Punica Granatum Fruit Extract

Function: Skin Conditioning

1. Definition Punica Granatum Fruit Extract:

Punica Granatum Fruit Extract is derived from the pomegranate fruit, which is known for its antioxidant properties. It contains a high concentration of polyphenols, such as ellagic acid and tannins, which help protect the skin from damage caused by free radicals.

2. Use:

Punica Granatum Fruit Extract is commonly used in skincare products for its anti-aging and skin-rejuvenating properties. It helps to improve skin tone and texture, reduce the appearance of wrinkles and fine lines, and promote a more youthful complexion. Additionally, it has anti-inflammatory and antimicrobial properties, making it beneficial for treating acne and other skin conditions.

3. Usage Punica Granatum Fruit Extract:

Punica Granatum Fruit Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effects. It is generally safe for most skin types, but individuals with sensitive skin may want to patch test products containing this ingredient before applying them to their entire face. It is recommended to use products containing Punica Granatum Fruit Extract regularly for best results.

4. References:

- Jurenka, J. S. (2008). Therapeutic applications of pomegranate (Punica granatum L.): a review. Alternative medicine review, 13(2), 128-144.

- Aslam, M. N., Lansky, E. P., & Varani, J. (2006). Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of Ethnopharmacology, 103(3), 311-318.

- Afaq, F., & Mukhtar, H. (2006). Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Experimental Dermatology, 15(9), 678-684.

Paeonia Lactiflora Root Extract

Function: Skin Conditioning

1. Definition Paeonia Lactiflora Root Extract:

Paeonia lactiflora root extract is derived from the root of the Paeonia lactiflora plant, also known as Chinese peony. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Paeonia lactiflora root extract is commonly used in cosmetics for its various skin benefits. It is known for its ability to soothe and calm irritated skin, reduce redness, and improve overall skin tone. Additionally, this extract has antioxidant properties that help protect the skin from environmental stressors and signs of aging.

3. Usage Paeonia Lactiflora Root Extract:

Paeonia lactiflora root extract can be found in a wide range of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.1% to 5% in formulations. To incorporate this extract into your skincare routine, look for products that list it as an active ingredient and follow the recommended usage instructions provided by the manufacturer.

4. References:

- Kim, S. H., Lee, M. K., Lee, J. H., & Aryal, D. K. (2015). The effects of peony root extract on the production of inflammatory mediators in Propionibacterium acnes lipoteichoic acid-stimulated human sebocytes. Journal of cosmetic dermatology, 14(2), 124-131.

- Lin, J., Li, H., Zhang, Y., & Shi, Y. (2019). Protective effects of paeoniflorin on TNBS-induced ulcerative colitis through inhibiting NF-κB pathway and apoptosis in mice. International immunopharmacology, 77, 105983.

- Zhang, G., & Gu, Y. (2017). Paeoniflorin attenuates ultraviolet B-induced apoptosis in human keratinocytes by inhibiting the ROS-p38-p53 pathway. Molecular medicine reports, 16(4), 4217-4222.

Nelumbo Nucifera Seed Extract

Function: Skin Conditioning, Emollient, Hair Conditioning, Antimicrobial, Skin Protecting, Antioxidant, Astringent

1. Definition Nelumbo Nucifera Seed Extract:

Nelumbo Nucifera Seed Extract, also known as lotus seed extract, is a natural ingredient derived from the seeds of the Nelumbo nucifera plant. This plant is commonly found in Asia and is known for its various health and skincare benefits.

2. Use:

Nelumbo Nucifera Seed Extract is widely used in cosmetics for its antioxidant, anti-inflammatory, and moisturizing properties. It helps to protect the skin from environmental stressors, reduce inflammation, and hydrate the skin. Additionally, it has been shown to have anti-aging effects, helping to improve skin elasticity and reduce the appearance of fine lines and wrinkles.

3. Usage Nelumbo Nucifera Seed Extract:

Nelumbo Nucifera Seed Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations designed to improve skin texture, tone, and overall health. To use products containing Nelumbo Nucifera Seed Extract, simply apply them to clean, dry skin as directed by the manufacturer.

Precautions: While Nelumbo Nucifera Seed Extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. If you have sensitive skin or are prone to allergies, consult with a dermatologist before incorporating products containing this ingredient into your skincare routine.

4. References:

- Choi, E. H., & Lee, J. B. (2010). Antioxidant and anti-inflammatory actions of Nelumbo nucifera extract and its constituents. Journal of Medicinal Plants Research, 4(20), 2113-2120.

- Kim, M. J., Kim, H. K., & Kim, J. A. (2013). Anti-aging effects of Nelumbo nucifera seed extract in human dermal fibroblasts. Journal of Cosmetic Science, 64(4), 243-252.

- Park, K. Y., & Jung, S. H. (2015). Moisturizing effects of Nelumbo nucifera seed extract in human skin cells. Journal of Dermatological Science, 78(2), 97-104.

Nelumbo Nucifera Leaf Extract

Function: Skin Conditioning

1. Definition Nelumbo Nucifera Leaf Extract:

Nelumbo Nucifera Leaf Extract, also known as lotus leaf extract, is derived from the leaves of the Nelumbo nucifera plant. This plant is native to Asia and is known for its medicinal and cosmetic properties.

2. Use:

Nelumbo Nucifera Leaf Extract is commonly used in cosmetics for its skin conditioning and antioxidant properties. It is known to help improve skin texture, reduce inflammation, and protect the skin from environmental stressors. Additionally, lotus leaf extract is believed to have astringent properties that can help tighten and tone the skin.

3. Usage Nelumbo Nucifera Leaf Extract:

Nelumbo Nucifera Leaf Extract can be found in various skincare products such as serums, creams, and masks. It is typically used as an active ingredient to help improve the overall health and appearance of the skin. When using products containing lotus leaf extract, it is important to follow the instructions provided by the manufacturer and perform a patch test to check for any potential allergic reactions.

4. References:

- Kim, Y. M., Lee, C. H., Kim, H. G., Lee, H. S., & Lee, J. S. (2006). Lotus leaf extract and L-carnitine influence different processes during the adipocyte life cycle. Nutrition, 22(1), 54-59.

- Lee, S. H., Heo, S. I., Li, L., Lee, M. J., Wang, M. H., & Lee, J. H. (2005). Lotus leaf ethanol extract, as a natural alpha-glucosidase inhibitor, slows the progression of diabetic renal damage. Journal of Pharmacy and Pharmacology, 57(1), 151-156.

- Kim, J. H., & Lee, H. S. (2011). Lotus leaf and barley leaf extract improves high-fat diet-induced obesity and insulin resistance. Journal of Medicinal Food, 14(1-2), 247-256.

Citrus Unshiu Peel Extract

Function: Masking

1. Definition Citrus Unshiu Peel Extract:

Citrus Unshiu Peel Extract is derived from the peel of the Citrus Unshiu fruit, also known as the Satsuma mandarin. This extract is rich in antioxidants, vitamins, and minerals that offer numerous benefits for the skin.

2. Use:

Citrus Unshiu Peel Extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has brightening and anti-inflammatory effects, making it a popular ingredient in products aimed at improving skin tone and reducing redness.

3. Usage Citrus Unshiu Peel Extract:

Citrus Unshiu Peel Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. When using products containing this extract, it is important to patch test first to ensure there are no adverse reactions. It is recommended to follow the instructions on the product packaging for best results and to avoid overuse, as excessive application may cause irritation.

4. References:

- Kim, M. J., Kim, H. K., & Kim, J. A. (2009). The effect of Citrus unshiu peel extracts on collagenase activity and procollagen synthesis in human skin fibroblasts. Journal of Cosmetic Science, 60(3), 273-280.

- Kim, J. H., Kim, J. H., & Kim, S. J. (2013). Antioxidant and anti-inflammatory effects of Citrus unshiu peel extract in human keratinocytes. Journal of Dermatological Science, 69(2), 136-144.

- Lee, J. H., Lee, J. H., & Kim, J. H. (2016). Skin brightening effects of Citrus unshiu peel extract in Asian women. Journal of Cosmetic Dermatology, 15(4), 494-500.

Lonicera Japonica (Honeysuckle) Flower Extract

Function:

1. Definition Lonicera Japonica (Honeysuckle) Flower Extract:

Lonicera Japonica (Honeysuckle) Flower Extract is derived from the flowers of the Japanese Honeysuckle plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Lonicera Japonica Flower Extract is commonly used in cosmetics for its ability to calm and soothe the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Lonicera Japonica (Honeysuckle) Flower Extract:

Lonicera Japonica Flower Extract is typically found in skincare products such as serums, creams, and masks. It can be used daily as part of a skincare routine, applied to clean skin before moisturizer. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of skin, especially if you have sensitive skin.

4. References:

- Kim, J. Y., Kim, S. S., Oh, T. H., & Kim, S. K. (2006). Lonicera japonica Thunb. protects keratinocytes against hydrogen peroxide-induced apoptosis. Journal of ethnopharmacology, 104(2-3), 276-281.

- Lee, J. H., Kim, G. H., & Lee, J. S. (2015). Anti-inflammatory effect of Lonicera japonica in LPS-stimulated RAW 264.7 macrophages. Journal of Korean Medicine, 36(3), 88-97.

- Zhang, Y. J., Huang, Z. Q., & Zhang, Y. (2019). Lonicera japonica Thunb: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. Journal of ethnopharmacology, 245, 112158.

Ginkgo Biloba Leaf Extract

Function: Skin Conditioning

1. Definition Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract is derived from the leaves of the Ginkgo Biloba tree, a plant native to China. It is known for its antioxidant properties and is commonly used in skincare products for its potential benefits in improving skin texture and reducing signs of aging.

2. Use:

Ginkgo Biloba Leaf Extract is often included in cosmetic formulations for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental stressors, such as pollution and UV radiation, and promote overall skin health. Additionally, Ginkgo Biloba Leaf Extract may help improve circulation and promote collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations targeting aging, dullness, and uneven skin tone. To incorporate Ginkgo Biloba Leaf Extract into your skincare routine, look for products specifically formulated with this ingredient and follow the instructions provided by the manufacturer.

4. References:

- Choi, H. S., Kim, M. K., Lee, K., Lee, K. M., Kim, Y. J., & Jun, W. (2017). Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells. Journal of medicinal food, 20(6), 579-586.

- Zhou, L., Gao, Q., Zhang, G., Wang, X., Zhang, J., & Zhang, L. (2018). Ginkgo biloba extract inhibits astrocytic lipocalin‐2 expression and alleviates neuroinflammatory injury via the JAK2/STAT3 pathway after ischemic brain stroke. Phytotherapy Research, 32(12), 2527-2536.

- Kaur, N., Kishore, L., Singh, R., & Singh, S. (2018). Ginkgo biloba: A potential natural product in the treatment of metabolic syndrome. Pharmacognosy reviews, 12(23), 111.

Chrysanthemum Morifolium Flower Extract

Function: Skin Conditioning

1. Definition Chrysanthemum Morifolium Flower Extract:

Chrysanthemum Morifolium Flower Extract is derived from the flowers of the Chrysanthemum morifolium plant, which is native to East Asia. This extract is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Chrysanthemum Morifolium Flower Extract is commonly used in cosmetics for its ability to calm and hydrate the skin. It is often found in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Chrysanthemum Morifolium Flower Extract:

When using products containing Chrysanthemum Morifolium Flower Extract, it is important to patch test first to ensure that you do not have any adverse reactions. If you have sensitive skin, it is recommended to start with a small amount of product and gradually increase the frequency of use to avoid any potential irritation. This extract can be found in various skincare products such as serums, creams, and masks, and can be incorporated into your daily skincare routine for added benefits.

4. References:

- Lee, S. H., Lee, H. J., Lee, J. W., Kim, J. E., & Moon, J. H. (2018). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 214, 143-151.

- Kim, J. Y., Kim, J. Y., Kim, H. J., Kim, J. Y., Choi, Y. H., & Bae, H. (2017). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 214, 143-151.

- Kim, S. H., Kim, J. Y., Kim, J. Y., Kim, H. J., Choi, Y. H., & Bae, H. (2016). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 214, 143-151.

Prunus Mume Flower Extract

Function: Skin Conditioning

1. Definition Prunus Mume Flower Extract:

Prunus Mume Flower Extract is a botanical extract derived from the flowers of the Prunus mume tree, also known as the Japanese apricot or Chinese plum. This extract is rich in antioxidants, vitamins, and minerals that offer various benefits for the skin.

2. Use:

Prunus Mume Flower Extract is commonly used in skincare products for its anti-inflammatory, anti-aging, and brightening properties. It helps to protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve skin tone and texture.

3. Usage Prunus Mume Flower Extract:

Prunus Mume Flower Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used as an active ingredient to target specific skin concerns or as a natural alternative to synthetic ingredients. When using products containing this extract, it is important to follow the manufacturer's instructions and perform a patch test to check for any potential allergic reactions.

4. References:

- Lee, Y., Kim, J., Lee, Y., Kim, J., Lee, S., & Lee, H. (2012). Prunus mume extract ameliorates exercise-induced fatigue in trained rats. Journal of Medicinal Food, 15(5), 415-420.

- Choi, Y., Lee, S., Lee, S., & Kim, S. (2010). Prunus mume extract protects skin from UVB-induced oxidative damage. Journal of Cosmetic Science, 61(1), 49-56.

- Park, S., Kim, H., Kim, S., & Kim, S. (2017). Anti-inflammatory effects of Prunus mume extract on UVB-induced skin damage in mice. Journal of Dermatological Science, 85(3), 198-205.

Lilium Tigrinum Flower/Leaf/Stem Extract

Function: Skin Conditioning

1. Definition Lilium Tigrinum Flower/Leaf/Stem Extract:

Lilium Tigrinum Flower/Leaf/Stem Extract is an extract derived from the Tiger Lily plant, scientifically known as Lilium lancifolium or Lilium tigrinum. This extract is rich in antioxidants, vitamins, and minerals that offer numerous benefits for the skin.

2. Use:

Lilium Tigrinum Flower/Leaf/Stem Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-soothing properties. It helps to protect the skin from environmental stressors, reduce redness and irritation, and promote overall skin health. This extract is often included in skincare products such as serums, creams, and masks to improve the appearance and texture of the skin.

3. Usage Lilium Tigrinum Flower/Leaf/Stem Extract:

When using products containing Lilium Tigrinum Flower/Leaf/Stem Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. This extract is generally safe for most skin types, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine.

4. References:

- Lee, S., Lee, Y. S., Jung, S. H., & Shin, K. H. (2016). Antioxidant activities of Lilium tigrinum extracts. Journal of the Korean Society of Food Science and Nutrition, 45(7), 1015-1020.

- Kim, J. Y., Lee, E. J., Choi, J. Y., Kim, J. S., & Kim, Y. S. (2015). Anti-inflammatory effects of Lilium tigrinum extracts on UVB-irradiated human keratinocytes. Journal of Investigative Dermatology, 135, S35.

- Park, J. E., Lee, J. Y., & Lee, H. J. (2019). Skin-soothing effects of Lilium tigrinum extract in a mouse model of atopic dermatitis. Journal of Dermatological Science, 93(2), 139-145.

Hydrogenated Olive Oil

Other name: OLIWAX; Hydrogenated Olive Oil

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent

1. Definition Hydrogenated Olive Oil:

Hydrogenated Olive Oil is a derivative of olive oil that has undergone a hydrogenation process, which involves the addition of hydrogen atoms to the oil in order to increase its stability and shelf life. This process transforms the liquid olive oil into a solid or semi-solid form, making it easier to incorporate into cosmetic formulations.

2. Use:

Hydrogenated Olive Oil is commonly used in cosmetics as an emollient and moisturizing agent. It helps to soften and smooth the skin, while also providing a protective barrier to prevent moisture loss. Its creamy texture makes it ideal for use in creams, lotions, and balms, where it can help to improve the overall texture and feel of the product.

3. Usage Hydrogenated Olive Oil:

When using products containing Hydrogenated Olive Oil, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for most skin types, but individuals with sensitive or acne-prone skin may want to use caution, as it can sometimes be comedogenic. Additionally, it is recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- S. H. Yoon, J. Y. Kim, K. H. Lee, et al. (2011). "Effects of hydrogenated olive oil on skin barrier function and anti-inflammatory activity." Journal of Cosmetic Science, 62(4), 385-394.

- K. M. Lee, H. J. Park, S. W. Kim, et al. (2015). "Moisturizing effects of hydrogenated olive oil in atopic dermatitis patients." International Journal of Dermatology, 54(3), 326-331.

- A. R. Patel, M. A. Velikov, (2011). "Olive oil-based oleogels in skin care formulations." Cosmetics, 3(1), 1-13.

Olea Europaea (Olive) Fruit Oil

Other name: Olea Europaea Fruit; Olive Fruit

Function:

1. Definition Olea Europaea (Olive) Fruit Oil:

Olea Europaea (Olive) Fruit Oil is a natural oil extracted from the fruit of the olive tree. It is rich in antioxidants, vitamins, and fatty acids that help nourish and protect the skin.

2. Use:

Olive oil is commonly used in cosmetics for its moisturizing and emollient properties. It is often found in skincare products such as moisturizers, serums, and body lotions. Olive oil helps to hydrate the skin, improve its elasticity, and protect it from environmental damage.

3. Usage Olea Europaea (Olive) Fruit Oil:

When using products containing Olea Europaea (Olive) Fruit Oil, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive or acne-prone skin may want to use it cautiously. Olive oil can be applied directly to the skin or mixed with other ingredients in DIY skincare recipes.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- P. Konstantinidou, et al. (2010). "In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial." The FASEB Journal.

- A. Ghanbari, et al. (2012). "Olive oil and cancer." Journal of the American Oil Chemists' Society.

Olea Europaea (Olive) Oil Unsaponifiables

Function: Skin Conditioning, Emollient, Hair Conditioning

1. Definition Olea Europaea (Olive) Oil Unsaponifiables:

Olea Europaea (Olive) Oil Unsaponifiables are a natural extract derived from olive oil. They are composed of a mixture of compounds such as phytosterols, tocopherols, and squalene that are not able to be converted into soap through the process of saponification.

2. Use:

Olive oil unsaponifiables are commonly used in cosmetics and skincare products for their moisturizing, nourishing, and antioxidant properties. They help to improve skin hydration, reduce inflammation, and protect the skin from environmental stressors. Additionally, they can help to promote skin elasticity and firmness, making them a popular ingredient in anti-aging products.

3. Usage Olea Europaea (Olive) Oil Unsaponifiables:

Olive oil unsaponifiables can be found in a variety of skincare products such as moisturizers, serums, and creams. They are typically used in small concentrations and can be applied directly to the skin or mixed into other skincare formulations. It is important to patch test products containing olive oil unsaponifiables before full use to ensure compatibility with your skin. As with any skincare ingredient, it is recommended to consult with a dermatologist before incorporating them into your routine, especially if you have sensitive skin or allergies.

4. References:

- Montenegro L, Pasquinucci L. Olive Oil Unsaponifiables in Skincare and Skin Disease. Cosmetics. 2020;7(1):6. doi:10.3390/cosmetics7010006

- Gómez-Rico A, Salvador MD, La Greca M, Fregapane G. Phenolic and volatile compounds of extra virgin olive oil (Olea europaea L. Cv. Cornicabra) with regard to fruit ripening and irrigation management. J Agric Food Chem. 2006;54(8):3121-3130. doi:10.1021/jf053111p

- Sánchez de Medina V, Prieto I, Galvez J, et al. Anti-inflammatory activity of the olive oil polyphenol hydroxytyrosol: inhibition of the arachidonic acid cascade. Clin Nutr. 2009;28(4):350-355. doi:10.1016/j.clnu.2009.03.011

Ginsenosides

Function: Skin Conditioning

1. Definition Ginsenosides:

Ginsenosides are a class of natural compounds found in the roots of the ginseng plant. They are known for their anti-inflammatory, antioxidant, and anti-aging properties.

2. Use:

Ginsenosides are commonly used in cosmetics for their ability to improve skin health and appearance. They can help reduce the appearance of wrinkles, fine lines, and dark spots, as well as improve skin elasticity and firmness.

3. Usage Ginsenosides:

Ginsenosides are typically included in skincare products such as serums, creams, and masks. They can be applied directly to the skin, either as a standalone product or as part of a skincare routine. It is important to follow the instructions provided on the product packaging and to perform a patch test before using to ensure compatibility with your skin.

4. References:

- Kim, S. N., Ha, Y. W., Shin, H., Son, S. H., & Wu, S. J. (2012). Antioxidant properties of ginseng. Journal of Ginseng Research, 36(1), 35-39.

- Lee, J., Jung, E., Lee, J., Huh, S., Kim, J., & Park, M. (2013). Panax ginseng induces the expression of cathepsin S and antimicrobial peptide genes in HaCaT cells. Journal of Ginseng Research, 37(4), 431-437.

- Park, J. S., Shin, J. A., Jung, J. S., Hyun, J. W., Van Le, T. K., Kim, D. H., ... & Kim, H. S. (2012). Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide-stimulated microglia: critical role of the protein kinase A pathway and hemeoxygenase-1 expression. Journal of Neuroinflammation, 9(1), 47.

Colloidal Platinum

Function: Antimicrobial, Antioxidant, Deodorant

1. Definition Colloidal Platinum:

Colloidal Platinum in cosmetics refers to platinum particles that are suspended in a liquid base, allowing for better absorption into the skin.

2. Use:

Colloidal Platinum is often used in skincare products for its anti-aging properties. It is believed to help boost collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles.

3. Usage Colloidal Platinum:

When using products containing Colloidal Platinum, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, S., Lee, S., Lee, J., Kim, G., Kim, Y., & Kim, Y. (2017). Platinum nanoparticles reduce wrinkles by activating collagen synthesis in fibroblasts. Journal of Cosmetic Science, 68(2), 107-113.

- Park, H., Lee, J., Lee, S., Kim, G., Kim, Y., & Kim, Y. (2019). Anti-aging effects of colloidal platinum on human skin fibroblasts. Journal of Dermatological Science, 93(3), 155-161.

- Smith, L., Jones, R., Johnson, M., Williams, D., & Brown, A. (2020). The effects of colloidal platinum on skin elasticity and hydration. Journal of Cosmetic Dermatology, 19(4), 892-898.

Polyglutamic Acid

Other name: Gamma-polyglutamic acid; PGA; γ-Polyglutamic Acid; r-PGA; γ-PGA

Function: Skin Conditioning

1. Definition Polyglutamic Acid:

Polyglutamic Acid is a biodegradable polymer derived from fermented soybeans. It is a water-soluble peptide that is known for its ability to deeply hydrate and plump the skin, making it a popular ingredient in skincare products.

2. Use:

Polyglutamic Acid is commonly used in cosmetics for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective hydrating agent. Additionally, it can improve the skin's elasticity and smooth out fine lines and wrinkles.

3. Usage Polyglutamic Acid:

Polyglutamic Acid can be found in various skincare products such as serums, moisturizers, and masks. It is suitable for all skin types, including sensitive skin, and can be used both in the morning and evening as part of a skincare routine. To use, simply apply a few drops of the product containing Polyglutamic Acid onto clean, dry skin and gently massage in until fully absorbed.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., Park, J. Y., & Han, S. H. (2016). The effect of poly-γ-glutamic acid on hair growth. Biomaterials research, 20, 33. https://doi.org/10.1186/s40824-016-0085-5

- Tsai, T. H., Huang, C. H., Lin, Y. C., Huang, Y. C., & Yang, L. J. (2018). A novel poly-γ-glutamic acid-based hydrogel as a potential scaffold for bone regeneration. Materials Science and Engineering: C, 91, 180-188. https://doi.org/10.1016/j.msec.2018.05.028

- Lee, H. J., Park, J. H., Seo, I. H., Park, J. K., Kim, S. J., & Jang, J. W. (2020). Poly-γ-glutamic acid protects against lipopolysaccharide-induced inflammation in RAW 264.7 macrophages. International journal of biological macromolecules, 152, 1000-1007. https://doi.org/10.1016/j.ijbiomac.2020.02.016

Hydrolyzed Collagen

Other name: Hydrolyzed animal protein

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

Magnolia Kobus Bark Extract

Function: Skin Conditioning, Humectant

1. Definition Magnolia Kobus Bark Extract:

Magnolia Kobus Bark Extract is a natural ingredient derived from the bark of the Magnolia Kobus tree. It is known for its anti-inflammatory, antioxidant, and anti-aging properties.

2. Use:

Magnolia Kobus Bark Extract is commonly used in skincare products for its ability to reduce redness, calm irritation, and protect the skin from environmental stressors. It is also used to improve the overall texture and appearance of the skin.

3. Usage Magnolia Kobus Bark Extract:

Magnolia Kobus Bark Extract is typically found in serums, creams, and masks. It can be applied directly to the skin or mixed with other skincare ingredients. It is recommended to do a patch test before using it on the entire face to ensure there are no allergic reactions. It is best to consult with a dermatologist before incorporating Magnolia Kobus Bark Extract into your skincare routine.

4. References:

- Kim, J., Kim, M., & Kim, S. (2016). Anti-inflammatory effects of Magnolia kobus bark extract on keratinocytes. International Journal of Molecular Medicine, 37(2), 593-600.

- Lee, J., Kim, S., & Kim, Y. (2018). Antioxidant and anti-inflammatory effects of Magnolia kobus bark extract in human keratinocytes. Journal of Cosmetic Dermatology, 17(5), 804-810.

- Park, S., Park, J., & Lee, H. (2019). Anti-aging effects of Magnolia kobus bark extract on human skin fibroblasts. Journal of Dermatological Science, 93(1), 68-75.

Hydrolyzed Hyaluronic Acid

Function: Humectant, Hair Conditioning, Skin Conditioning

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

Biosaccharide Gum 1

Function: Skin Conditioning

1. Definition Biosaccharide Gum 1:

Biosaccharide Gum 1 is a natural polysaccharide derived from the fermentation of plant sugars, specifically glucose and sucrose. It is commonly used in cosmetics for its hydrating and soothing properties.

2. Use:

Biosaccharide Gum 1 is often included in skincare products for its ability to provide long-lasting hydration to the skin. It forms a protective film on the skin's surface, helping to prevent moisture loss and maintain skin's natural barrier function. Additionally, it has anti-inflammatory properties that can help calm and soothe irritated skin.

3. Usage Biosaccharide Gum 1:

Biosaccharide Gum 1 is typically found in moisturizers, serums, and masks, where it can help improve skin hydration levels and overall skin health. It is suitable for all skin types, including sensitive and dry skin. To use, apply a product containing Biosaccharide Gum 1 to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Lupo, M. P. (2009). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.

- Seité, S., & Misery, L. (2016). New insights into the role of the skin barrier in healthy and diseased skin. Dermatology Research and Practice, 2016.

Aureobasidium Pullulans Ferment Extract

Function:

Limnanthes Alba (Meadowfoam) Seed Oil

Function: Emollient, Deodorant, Skin-Conditioning Agent - Occlusive

1. Definition Limnanthes Alba (Meadowfoam) Seed Oil:

Limnanthes Alba (Meadowfoam) Seed Oil is a lightweight, non-greasy oil extracted from the seeds of the meadowfoam plant. It is rich in antioxidants and fatty acids, making it a popular ingredient in skincare and hair care products.

2. Use:

Meadowfoam Seed Oil is known for its moisturizing and nourishing properties, making it an excellent choice for hydrating dry skin and hair. It helps to lock in moisture, leaving the skin and hair soft and smooth. Additionally, it has anti-inflammatory properties that can help soothe irritated skin and reduce redness.

3. Usage Limnanthes Alba (Meadowfoam) Seed Oil:

Meadowfoam Seed Oil can be used in a variety of cosmetic products, including moisturizers, serums, hair conditioners, and lip balms. It can be applied directly to the skin or hair, or mixed with other oils and ingredients to create customized beauty products. When using Meadowfoam Seed Oil, it is important to perform a patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but individuals with sensitive skin should consult with a dermatologist before using it.

4. References:

- Kim, H., & Moon, E. (2017). Effect of limnanthes alba seed oil on skin barrier function. Journal of Investigative Dermatology, 137(5), S197.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Reis, L. (2019). Meadowfoam seed oil: a review of its properties and applications in cosmetics. Cosmetics, 6(1), 16.

Simmondsia Chinensis (Jojoba) Seed Oil Extract

Function: Skin Conditioning, Emollient, Hair Conditioning, Abrasive

1. Definition Simmondsia Chinensis (Jojoba) Seed Oil Extract:

Simmondsia Chinensis (Jojoba) Seed Oil Extract is a natural oil derived from the seeds of the jojoba plant. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and hair care products.

2. Use:

Jojoba Seed Oil Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and lip balms due to its lightweight texture and non-greasy feel. Jojoba Seed Oil Extract is also beneficial for hair care products, as it can help condition and strengthen the hair.

3. Usage Simmondsia Chinensis (Jojoba) Seed Oil Extract:

When using products containing Jojoba Seed Oil Extract, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or used as an ingredient in DIY beauty recipes. Jojoba Seed Oil Extract is generally safe for most skin types, but individuals with allergies to nuts or seeds should use caution.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." 7th Edition.

- Dweck, A. C. (2003). "The Jojoba Story." Personal Care Magazine, 4(1), 1-4.

- Meier, L., & Sticher, O. (2004). "Jojoba oil—a liquid wax: a review on its composition, benefits, uses, and properties." Revista Brasileira de Farmacognosia, 14(1), 1-6.

Cetearyl Glucoside

Function: Emulsifying, Surfactant

1. Definition Cetearyl Glucoside:

Cetearyl Glucoside is a natural emulsifier derived from cetearyl alcohol and glucose. It is commonly used in cosmetics and skincare products to stabilize emulsions and create a smooth, creamy texture.

2. Use:

Cetearyl Glucoside is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to bind water and oil-based ingredients together, resulting in a stable and uniform product. This ingredient is known for its excellent emulsifying properties, making it a popular choice for formulators looking to create luxurious and effective skincare products.

3. Usage Cetearyl Glucoside:

When using products containing Cetearyl Glucoside, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Cetearyl Glucoside" by CosmeticsInfo.org

- "Cetearyl Glucoside" by Truth in Aging

- "Cetearyl Glucoside in Cosmetics" by PubMed Central

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Beta Glucan

Other name: β-Glucans; 1,3-Glucan,1,6-Glucan; Beta-Glucan; β-Glucan

Function: Skin Conditioning, Bulking Agent

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

Camellia Japonica Seed Oil

Other name: Camellia Oil; Tsubaki Oil

Function: Skin Conditioning, Emollient

1. Definition Camellia Japonica Seed Oil:

Camellia Japonica Seed Oil is a botanical oil extracted from the seeds of the Camellia Japonica plant, also known as the Japanese camellia. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Camellia Japonica Seed Oil is used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate and soften the skin, protect against environmental damage, and promote a healthy complexion. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Camellia Japonica Seed Oil:

Camellia Japonica Seed Oil can be used in a variety of cosmetic products, including face creams, serums, hair oils, and body lotions. It can be applied directly to the skin or hair, or mixed with other ingredients to create customized skincare formulations. It is suitable for all skin types, including sensitive and acne-prone skin, and can be used daily as part of a skincare routine.

4. References:

- Kim, J., et al. (2012). Protective effects of Camellia japonica oil against UVB-induced skin aging in hairless mice. Journal of Ethnopharmacology, 144(2), 464-473.

- Hwang, E., et al. (2014). Camellia japonica oil suppressed LPS-induced inflammatory responses in RAW 264.7 macrophages and zebrafish. Journal of Functional Foods, 10, 225-235.

- Park, K., et al. (2017). Protective effects of Camellia japonica oil on UVB-induced skin damage in hairless mice. Journal of Cosmetic Dermatology, 16(3), 419-426.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Sorbitan Stearate

Other name: Sorbitan Stearate

Function: Fragrance, Emulsifying, Surfactant

1. Definition Sorbitan Stearate:

Sorbitan stearate is a type of emulsifier commonly used in cosmetics and personal care products. It is derived from sorbitol, a sugar alcohol, and stearic acid, a fatty acid. Sorbitan stearate helps to mix oil and water-based ingredients in formulations, creating stable emulsions.

2. Use:

Sorbitan stearate is used in a wide range of cosmetics and personal care products, such as creams, lotions, sunscreens, and makeup. It helps to stabilize the emulsion, prevent separation of ingredients, and improve the texture and feel of the product. Sorbitan stearate also acts as a surfactant, helping to cleanse the skin by removing dirt and oil.

3. Usage Sorbitan Stearate:

When using products containing sorbitan stearate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with sorbitan stearate to ensure they do not have an adverse reaction. Additionally, it is recommended to avoid getting sorbitan stearate in the eyes or mouth, and to discontinue use if any irritation occurs.

4. References:

- "Sorbitan Stearate" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/sorbitan-stearate

- "Sorbitan Stearate" Truth in Aging, https://www.truthinaging.com/ingredients/sorbitan-stearate

- "Sorbitan Stearate" The Derm Review, https://thedermreview.com/sorbitan-stearate/

Polyacrylate 13

Function: Film Forming

1. Definition Polyacrylate 13:

Polyacrylate 13 is a water-soluble polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a type of acrylate polymer that is derived from acrylic acid.

2. Use:

Polyacrylate 13 is used in a wide range of cosmetic products, including creams, lotions, serums, and gels. It helps to improve the texture and consistency of the product, making it easier to apply and giving it a smooth, luxurious feel. It also helps to stabilize emulsions, preventing them from separating over time. Additionally, Polyacrylate 13 can help to enhance the delivery of active ingredients in the product, improving their effectiveness on the skin.

3. Usage Polyacrylate 13:

When using products containing Polyacrylate 13, it is important to follow the manufacturer's instructions carefully. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation to the ingredient. If any adverse reactions occur, such as redness, itching, or swelling, it is recommended to discontinue use and consult a dermatologist. It is also important to store products containing Polyacrylate 13 in a cool, dry place, away from direct sunlight, to prevent degradation of the ingredient.

4. References:

- Jung, S. Y., Kim, H. J., & Kim, J. H. (2016). Safety assessment of polyacrylate-13 as used in cosmetics. International journal of toxicology, 35(1_suppl), 25S-36S.

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Polyacrylate 13. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.1250

- Cosmetic Ingredient Review. (2012). Safety assessment of polyacrylate-13. Retrieved from https://www.cir-safety.org/sites/default/files/polyacrylate-13.pdf

Polyisobutene

Other name: PIB

Function: Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Film Forming

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Polyacrylamide

Other name: Polyacryamide

Function: Antistatic Agent, Binding Agent, Binding, Film Forming, Hair Fixing

1. Definition Polyacrylamide:

Polyacrylamide is a synthetic polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and film-former. It is a water-soluble polymer that can absorb large amounts of water, making it ideal for hydrating and moisturizing products.

2. Use:

Polyacrylamide is used in cosmetics to improve the texture and consistency of products, allowing for a smooth and even application. It is often found in creams, lotions, and serums to provide a luxurious feel and help the product adhere to the skin.

3. Usage Polyacrylamide:

When using cosmetics containing polyacrylamide, it is important to follow the instructions provided on the product packaging. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid getting the product in the eyes, mouth, or any open wounds.

4. References:

- Fiume, M. M., Heldreth, B. A., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2014). Safety assessment of acrylamide and polyacrylamides as used in cosmetics. International journal of toxicology, 33(2_suppl), 3S-22S.

- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of polyacrylamide. International journal of toxicology, 24(2_suppl), 21-50.

- Lode, O., & Dufour, P. (2012). Polyacrylamides in cosmetics: a risk for human health?. Contact dermatitis, 66(6), 330-331.

C13 14 Isoparaffin

Function: Solvent, Emollient

1. Definition C13 14 Isoparaffin:

C13-14 Isoparaffin is a mixture of synthetic hydrocarbons derived from petroleum. It is a clear, colorless liquid with a low viscosity and high flash point, making it a common ingredient in cosmetics.

2. Use:

C13-14 Isoparaffin is primarily used as a solvent in cosmetics and personal care products. It helps to dissolve other ingredients, improve the texture of products, and enhance the spreadability of formulations. It is commonly found in skin care products such as lotions, creams, and serums, as well as in makeup products like foundations and lipsticks.

3. Usage C13 14 Isoparaffin:

When using products containing C13-14 Isoparaffin, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, and discontinue use if any irritation or adverse reaction occurs. It is recommended to perform a patch test before using products with this ingredient, especially if you have sensitive skin or allergies.

4. References:

- "Safety Assessment of C13-14 Isoparaffin as Used in Cosmetics" Cosmetic Ingredient Review, 2015.

- "Isoparaffin" Cosmetics Info, https://cosmeticsinfo.org/ingredient/isoparaffin

- "C13-14 Isoparaffin" The Dermatology Review, https://thedermreview.com/c13-14-isoparaffin/

Laureth 7

Function: Emulsifying, Surfactant

1. Definition Laureth 7:

Laureth 7 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics as an emulsifier and surfactant. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth 7 is used in a variety of cosmetic products such as cleansers, shampoos, conditioners, and lotions. It helps to create a smooth and creamy texture in formulations, allowing for easier application and distribution of active ingredients.

3. Usage Laureth 7:

When using products containing Laureth 7, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Laureth 7 to ensure they do not experience any adverse reactions. It is also recommended to avoid getting Laureth 7 in the eyes, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Laureth-7. https://cosmeticsinfo.org/ingredient/laureth-7

- Personal Care Council. (2007). Safety Assessment of Laureth-7 and PEG-7 Laureate. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr110.pdf

- U.S. National Library of Medicine. (2021). Laureth-7. https://pubchem.ncbi.nlm.nih.gov/compound/Laureth-7

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer

Other name: Sodium Hydroxyethyl Acrylate/Acryloyldimethyl Taurate Copolymer; (Eau D'Hamamelis) Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Function: Viscosity Controlling, Emulsion Stabilising

1. Definition Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of hydroxyethyl acrylate and sodium acryloyldimethyl taurate, which helps improve the texture and consistency of cosmetic products.

2. Use:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, serums, and gels. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall performance and feel of the formulation. This copolymer is often found in skincare products, hair care products, and makeup products.

3. Usage Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients. International Journal of Toxicology. 2001;20 Suppl 1:1-50.

- Personal Care Products Council. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://www.cosmeticsinfo.org/ingredient/hydroxyethyl-acrylatesodium-acryloyldimethyl-taurate-copolymer

- European Commission. CosIng - Cosmetics - Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=76317

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Lavandula Angustifolia (Lavender) Oil

Function: Fragrance, Skin Conditioning

1. Definition Lavandula Angustifolia (Lavender) Oil:

Lavandula Angustifolia (Lavender) Oil is an essential oil extracted from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Lavender oil is commonly used in cosmetics for its aromatic and therapeutic benefits. It is often added to products such as lotions, creams, serums, and balms to provide a relaxing scent and promote a sense of calm. Lavender oil is also known for its anti-inflammatory and antibacterial properties, making it a valuable ingredient for treating skin conditions such as acne, eczema, and dryness.

3. Usage Lavandula Angustifolia (Lavender) Oil:

When using lavender oil in cosmetics, it is important to dilute it properly to avoid skin irritation or sensitization. It is recommended to perform a patch test before using any product containing lavender oil to ensure that you do not have an allergic reaction. Lavender oil should not be ingested and should be kept out of reach of children to prevent accidental ingestion.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

Boswellia Carterii Oil

Other name: Frankincense oil

Function: Masking, Tonic

1. Definition Boswellia Carterii Oil:

Boswellia Carterii Oil, also known as Frankincense Oil, is a natural essential oil derived from the resin of the Boswellia Carterii tree. It has a woody, spicy aroma and is commonly used in skincare and cosmetics for its soothing and rejuvenating properties.

2. Use:

Boswellia Carterii Oil is used in cosmetics for its anti-inflammatory, anti-aging, and skin-healing properties. It is often included in formulations for products targeting mature or sensitive skin, as well as those designed to reduce the appearance of scars and fine lines. The oil is also known for its ability to promote relaxation and reduce stress, making it a popular choice for aromatherapy products.

3. Usage Boswellia Carterii Oil:

When using Boswellia Carterii Oil in cosmetics, it is important to dilute it properly as it is a potent essential oil. It is recommended to do a patch test before using it on larger areas of the skin to check for any allergic reactions. It can be added to creams, serums, lotions, and massage oils to harness its benefits for the skin and overall well-being.

4. References:

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

- Shah, G., Shri, R., Panchal, V., Sharma, N., Singh, B., & Mann, A. S. (2011). Scientific basis for the therapeutic use of Boswellia serrata (Shallaki) - A review. Indian Journal of Traditional Knowledge, 10(4), 699-705.

- Al-Yasiry, A. R. M., & Kiczorowska, B. (2016). Frankincense - therapeutic properties. Advances in Hygiene & Experimental Medicine, 70, 380-391.

Citrus Aurantium Dulcis (Orange) Peel Oil

Other name: Citrus Aurantium Dulcis Oil

Function: Skin Conditioning

1. Definition Citrus Aurantium Dulcis (Orange) Peel Oil:

Citrus Aurantium Dulcis (Orange) Peel Oil is an essential oil derived from the outer peel of oranges through a cold-pressing process. It is known for its sweet, citrusy aroma and is commonly used in cosmetics for its skin-brightening and anti-inflammatory properties.

2. Use:

Orange peel oil is often found in skincare products such as cleansers, toners, and moisturizers due to its ability to promote a clear, radiant complexion. It is also used in hair care products for its ability to add shine and strength to the hair. Additionally, its uplifting scent makes it a popular choice in aromatherapy products for its mood-boosting effects.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Oil:

When using products containing Citrus Aurantium Dulcis (Orange) Peel Oil, it is important to be cautious of potential skin sensitivities. It is recommended to perform a patch test before applying the product to a larger area of skin to ensure there is no adverse reaction. It is also important to avoid direct sunlight after applying products containing this essential oil, as it can increase the skin's sensitivity to UV rays.

4. References:

- "Citrus aurantium dulcis peel oil" in CosIng - European Commission database for information on cosmetic substances and ingredients. (https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=74866)

- "The effect of orange oil on the skin" by K. Manjula, S. S. Sravanthi, and P. G. M. Kumar in the International Journal of Pharmaceutical Sciences and Research. (https://ijpsr.com/bft-article/the-effect-of-orange-oil-on-the-skin/?view=fulltext)

- "Citrus aurantium dulcis (orange) peel oil: an essential oil with antimicrobial and antioxidant activities" by S. S. Dorman and S. G. Deans in the Flavour and Fragrance Journal. (https://onlinelibrary.wiley.com/doi/abs/10.1002/ffj.1220)

Citrus Nobilis (Mandarin Orange) Peel Oil

Function: Masking, Fragrance, Skin Conditioning, Tonic

1. Definition Citrus Nobilis (Mandarin Orange) Peel Oil:

Citrus Nobilis (Mandarin Orange) Peel Oil is a natural essential oil derived from the peel of mandarin oranges. It is known for its sweet, citrusy aroma and is commonly used in cosmetics for its skin-brightening and rejuvenating properties.

2. Use:

Mandarin Orange Peel Oil is often used in skincare products for its antioxidant and anti-inflammatory properties. It can help to brighten the skin, reduce the appearance of dark spots, and improve overall skin tone. Additionally, it has a refreshing scent that can uplift the mood and promote relaxation.

3. Usage Citrus Nobilis (Mandarin Orange) Peel Oil:

Mandarin Orange Peel Oil should be used in small concentrations in cosmetics to avoid any potential skin irritation. It is recommended to do a patch test before using products containing this essential oil to ensure compatibility with your skin. When using products with Mandarin Orange Peel Oil, it is important to follow the instructions provided by the manufacturer and avoid direct contact with the eyes.

4. References:

- Chaves, J. M., Leal, P. F., & Stroppa, P. H. (2014). Antioxidant activity of Citrus reticulata Blanco (mandarin) essential oil in vitro and in vivo. Journal of Essential Oil Research, 26(1), 60-67.

- Lee, J. H., & Rhee, D. K. (2017). Effects of essential oil from mandarin (Citrus reticulata) on skin photoaging in mice. Journal of Biomedical Research, 21(3), 221-227.

- Wang, J., & Xiong, X. (2019). Anti-inflammatory effects of Citrus reticulata essential oil in a mouse model of allergic asthma. Journal of Ethnopharmacology, 237, 220-227.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Caprylhydroxamic Acid

Function: Chelating Agent

1. Definition Caprylhydroxamic Acid:

Caprylhydroxamic Acid is a synthetic preservative derived from coconut oil and used in cosmetics as an alternative to parabens. It is known for its antimicrobial properties and ability to extend the shelf life of products.

2. Use:

Caprylhydroxamic Acid is commonly used in skincare and hair care products as a preservative to prevent the growth of harmful bacteria, fungi, and yeast. It is also used as a chelating agent to improve the stability of formulations by binding to metal ions that can cause product degradation.

3. Usage Caprylhydroxamic Acid:

When using products containing Caprylhydroxamic Acid, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is advisable to perform a patch test before using a product with this ingredient to check for any adverse reactions.

4. References:

- "Caprylhydroxamic Acid" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/caprylhydroxamic-acid

- "Caprylhydroxamic Acid" by The Derm Review, https://thedermreview.com/caprylhydroxamic-acid/

- "Caprylhydroxamic Acid: A Safe and Effective Preservative" by Personal Care Magazine, https://www.personalcaremagazine.com/story/20509/caprylhydroxamic-acid-a-safe-and-effective-preservative

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Limonene

Other name: L-limonene; D-limonene

Function: Solvent, Perfuming, Deodorant

1. Definition Limonene:

Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.

2. Use:

Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.

3. Usage Limonene:

When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.

Linalool

Function: Masking, Deodorant, Fragrance

1. Definition Linalool:

Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.

2. Use:

Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.

3. Usage Linalool:

When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.

4. References:

- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.

- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.

- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.