Full ingredients list Teoxane Advanced Perfecting Shield SPF ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	A	Diisopropyl Sebacate (Solvent, Skin Conditioning, Emollient, Plasticizer)
6		Ethylhexyl Methoxycinnamate (Uv Absorber, Uv Filter)	UV Protection Bad for sensitive skin
2		Diethylamino Hydroxybenzoyl Hexyl Benzoate (Uv Absorber, Uv Filter)	UV Protection
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
		Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (Uv Filter)	UV Protection
		Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine (Uv Absorber, Skin Conditioning, Uv Filter)	UV Protection
1		Methylpropanediol (Solvent)
3		Phenylbenzimidazole Sulfonic Acid (Uv Absorber, Uv Filter)	UV Protection
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
	B	Phosphate Buffered Saline (Solvent)
1	A	Hdi/ Trimethylol Hexyllactone Crosspolymer (Anticaking Agent)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
1		Ethylhexyl Triazone (Uv Absorber, Uv Filter)	UV Protection
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
2	B	Decyl Glucoside (Emulsion Stabilising, Surfactant, Cleansing)
1	B	Isodecyl Neopentanoate (Skin Conditioning, Emollient)
1	B	Lauryl Lactate (Skin Conditioning, Emollient, Fragrance)
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1 3		Ceteth 10 Phosphate (Surfactant, Cleansing)
1	B	Dicetyl Phosphate (Surfactant, Emulsifying)
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1		Acrylates/ C10 30 Alkyl Acrylate Crosspolymer (Viscosity Controlling, Emulsion Stabilising, Film Forming)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin
1		CI 77492 (Colorant, Cosmetic Colorant)
1		Caprylhydroxamic Acid (Chelating Agent)
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1 2		Thioctic Acid (Antioxidant)
		C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate (Skin Conditioning, Emollient, Humectant)
1		Decarboxy Carnosine Hcl (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1 2	B	O Cymen 5 Ol (Preservative, Cosmetic Biocide)
1	B	Sodium Pca (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
1 3	B	Sodium Lactate (Humectant, pH adjusting agent, Exfoliant, Keratolytic)
3	B	Propylene Glycol (Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous)	Good for dry skin
1 2		CI 77491 (Colorant, Cosmetic Colorant)
4		Disodium Acetyl Glucosamine Phosphate
		Sodium Hyaluronate Crosspolymer-2 (Humectant)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
3	A	Bht (Masking, Fragrance, Antioxidant)
1 2		Lecithin (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant)
1		Glutathione (Fragrance, Reducing)	Brightening
4		Alcohol Denat (Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent)	Bad for sensitive skin Bad for dry skin Alcohol
1	A	Palmitoyl Tripeptide 1 (Skin Conditioning)
1 4	A	Polyquaternium 7 (Antistatic Agent, Film Forming, Hair Fixing)
1	A	Palmitoyl Tetrapeptide 7 (Skin Conditioning)
1		Pyridoxine Hcl (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1	B	Acetyl Cysteine (Skin Conditioning, Antioxidant)
1	A	Lysine HCL (Hair Conditioning, Skin Conditioning)
1	A	Valine (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Isoleucine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Leucine (Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Threonine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Hair Waving Or Straightening)
1	A	Glycine (Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous)
2 3		Zinc Acetate (Antimicrobial, Skin Protecting, Cosmetic Astringent, Cosmetic Biocide)
1	A	Proline (Fragrance, Hair Conditioning, Skin Conditioning)
		Copper Sulfate (Skin Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Diisopropyl Sebacate

Function: Solvent, Skin Conditioning, Emollient, Plasticizer

1. Definition Diisopropyl Sebacate:

Diisopropyl Sebacate is a synthetic ester derived from sebacic acid and isopropyl alcohol. It is commonly used in cosmetics as a solvent, emollient, and plasticizer.

2. Use:

Diisopropyl Sebacate is used in cosmetics for its ability to improve the texture and spreadability of products. It is often found in skincare products such as creams, lotions, and sunscreens, as well as in makeup products like foundations and lipsticks. Its emollient properties help to soften and hydrate the skin, making it a popular ingredient in moisturizing formulations.

3. Usage Diisopropyl Sebacate:

When using products containing Diisopropyl Sebacate, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. Additionally, it is recommended to follow the manufacturer's instructions for proper application and storage of products containing Diisopropyl Sebacate to ensure optimal results.

4. References:

- "Diisopropyl Sebacate" - CosmeticsInfo.org

- "Safety Assessment of Diisopropyl Sebacate" - Cosmetic Ingredient Review

- "Formulation and Evaluation of Sunscreen Cream Containing Diisopropyl Sebacate" - International Journal of Pharmaceutical Sciences and Research

Ethylhexyl Methoxycinnamate

Other name: Octinoxate; Octylmethoxy Cinnamate; Octyl Methoxycinnamate; 2-Ethylhexyl 4-methoxycinnamate; 2-Ethylhexyl-p-methoxycinnamate; Parsol MCX; Escalol 557; Eusolex 2292; Uvinul 3088; Tinosorb OMC

Function: Uv Absorber, Uv Filter

1. Definition Ethylhexyl Methoxycinnamate:

Ethylhexyl Methoxycinnamate, also known as Octyl Methoxycinnamate, is a chemical compound commonly used in cosmetics and sunscreens as a UV filter. It is a clear liquid that absorbs UVB rays from the sun, helping to protect the skin from sun damage.

2. Use:

Ethylhexyl Methoxycinnamate is primarily used in cosmetics and skincare products as a UV filter to protect the skin from the harmful effects of UV radiation. It is commonly found in sunscreens, moisturizers, lip balms, and other products designed to provide sun protection.

3. Usage Ethylhexyl Methoxycinnamate:

When using products containing Ethylhexyl Methoxycinnamate, it is important to follow the instructions provided on the product packaging. Apply sunscreen with this ingredient generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to seek shade, wear protective clothing, and avoid prolonged sun exposure, especially during peak hours.

4. References:

- Klammer H, Schlecht C, Wuttke W, Schmutzler C, Gotthardt I, Köhrle J, Jarry H. Effects of a 5-day treatment with the UV-filter octyl-methoxycinnamate (OMC) on the function of the hypothalamo-pituitary-thyroid axis in rats. Toxicology. 2007;238(2-3):192-9. doi: 10.1016/j.tox.2007.06.017. Epub 2007 Jul 3. PMID: 17658655.

- Schlumpf M, Cotton B, Conscience M, Haller V, Steinmann B, Lichtensteiger W. In vitro and in vivo estrogenicity of UV screens. Environ Health Perspect. 2001 Mar;109(3):239-44. doi: 10.1289/ehp.01109239. PMID: 11333190; PMCID: PMC1240267.

- Janjua NR, Mogensen B, Andersson AM, Petersen JH, Henriksen M, Skakkebaek NE, Wulf HC. Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. J Invest Dermatol. 2004 May;122(5):1257-61. doi: 10.1111/j.0022-202X.2004.22603.x. PMID: 15140223.

Diethylamino Hydroxybenzoyl Hexyl Benzoate

Other name: Uvinul A Plus

Function: Uv Absorber, Uv Filter

1. Definition Diethylamino Hydroxybenzoyl Hexyl Benzoate:

Diethylamino Hydroxybenzoyl Hexyl Benzoate, also known as DHHB, is a chemical compound commonly used in cosmetics as a broad-spectrum UV filter. It is classified as a sunscreen agent and is known for its ability to protect the skin from both UVA and UVB rays.

2. Use:

Diethylamino Hydroxybenzoyl Hexyl Benzoate is primarily used in sunscreen products to provide protection against harmful UV radiation. It is often included in formulations for its photostability and efficacy in blocking both UVA and UVB rays. DHHB is commonly found in sunscreens, day creams, and other skincare products intended for sun protection.

3. Usage Diethylamino Hydroxybenzoyl Hexyl Benzoate:

When using products containing Diethylamino Hydroxybenzoyl Hexyl Benzoate, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with DHHB generously to all exposed skin, including the face, neck, and any other areas not covered by clothing. Reapply sunscreen every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2011.11.003

- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747

- Food and Drug Administration (FDA). Sunscreen Drug Products for Over-the-Counter Human Use. Code of Federal Regulations Title 21, Volume 5. Revised as of April 1, 2020. Accessed June 10, 2021. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=352

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol

Other name: Tinosorb M; Bisoctrizole; Ultraviolet Absorbent UV-360; PARSOL Max

Function: Uv Filter

1. Definition Methylene Bis-Benzotriazolyl Tetramethylbutylphenol:

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, also known as Tinosorb M, is a chemical compound used in sunscreens and other cosmetic products as a broad-spectrum UV filter. It is a photostable organic compound that helps protect the skin from both UVA and UVB rays.

2. Use:

Tinosorb M is primarily used in sunscreens to provide protection against the harmful effects of UV radiation. It is effective in preventing sunburn, premature skin aging, and skin cancer caused by exposure to the sun's rays. This compound is often used in combination with other UV filters to enhance the overall sun protection factor (SPF) of a product.

3. Usage Methylene Bis-Benzotriazolyl Tetramethylbutylphenol:

When using products containing Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, it is important to follow the instructions provided on the packaging. Apply the sunscreen generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is recommended to use sunscreen with a minimum SPF of 30 and to seek shade during peak sun hours to further protect the skin.

4. References:

- M. G. Leblanc, M. C. Gaudreault, M. S. Corbeil, J. P. H. Bouchard, and M. G. Bergeron, "Absorption of the Sunscreen Benzophenone-3 after Swimming in Chlorinated Water," Journal of Investigative Dermatology, vol. 123, no. 5, pp. 917-922, 2004.

- E. Berardesca, M. Distante, and M. Vignoli, "Efficacy of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol in the Prevention of Polymorphic Light Eruption," Dermatology, vol. 207, no. 3, pp. 312-315, 2003.

- J. A. Parrish, M. A. Pathak, and L. D. Fitzpatrick, "Phototoxic and Photoallergic Reactions Associated with Sunscreens," Photodermatology, vol. 1, no. 2, pp. 79-98, 1984.

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Other name: BisEthylhexyloxyphenol Methoxyphenyl Triazine; Tinosorb S; Anisotriazine; Bemotrizinol

Function: Uv Absorber, Skin Conditioning, Uv Filter

1. Definition Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, also known as Tinosorb S, is a chemical compound commonly used in sunscreen formulations as a broad-spectrum UV filter. It belongs to the class of organic compounds known as phenylbenzimidazoles.

2. Use:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is used in cosmetic products, especially in sunscreens, to provide protection against both UVA and UVB rays. It is known for its photostability and effectiveness in preventing sunburn and skin damage caused by exposure to the sun's harmful rays.

3. Usage Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

When using products containing Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, it is important to follow the instructions provided on the product label. Apply the sunscreen generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Moyal D. (2008). Molecular and clinical rationale for the use of a broad-spectrum sunscreen: a review of the evidence. Journal of Drugs in Dermatology, 7(2 Suppl):6-12.

- Matta M.K., et al. (2010). Effect of sunscreen application on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA, 323(3):256-67.

- Nash J.F., et al. (2006). Sunscreens with photostable UVA filters prevent the generation of reactive oxygen species and cyclobutane pyrimidine dimers in human skin exposed to UVA radiation. Pigment Cell Research, 19(4):364-74.

Methylpropanediol

Function: Solvent

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

Phenylbenzimidazole Sulfonic Acid

Other name: 2-phenylbenzimidazole-5-sulfonic acid; Phenylbenzimidazole Sulfonic Acid

Function: Uv Absorber, Uv Filter

1. Definition Phenylbenzimidazole Sulfonic Acid:

Phenylbenzimidazole Sulfonic Acid, also known as Ensulizole, is a water-soluble organic compound commonly used in sunscreen formulations to provide protection against UVB radiation.

2. Use:

Phenylbenzimidazole Sulfonic Acid is primarily used in cosmetics and personal care products as a UV filter to absorb and reflect UVB rays. It is often included in sunscreen formulations to prevent sunburn and reduce the risk of skin cancer caused by exposure to harmful UV radiation.

3. Usage Phenylbenzimidazole Sulfonic Acid:

When using products containing Phenylbenzimidazole Sulfonic Acid, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with this ingredient generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to avoid prolonged sun exposure, especially during peak hours when the sun's rays are strongest.

4. References:

- Kaur CD, Saraf S. In vitro sun protection factor determination of herbal oils used in cosmetics. Pharmacognosy Res. 2010;2(1):22-25. doi:10.4103/0974-8490.60586

- Cole C, Gazdik M, DeClercq J. Skin protection against UV light by dietary antioxidants. Food Funct. 2015;6(7):2071-2074. doi:10.1039/c5fo00343e

- Matta MK, Zusterzeel R, Pilli NR, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Phosphate Buffered Saline

Function: Solvent

1. Definition Phosphate Buffered Saline:

Phosphate Buffered Saline (PBS) is a solution commonly used in the cosmetics industry as a buffer to maintain the pH of products and to provide a stable environment for various ingredients.

2. Use:

PBS is utilized in cosmetics to control the acidity or alkalinity of formulations, helping to maintain the desired pH level. It is particularly useful in skincare products, such as creams and serums, to ensure that the active ingredients remain effective and stable.

3. Usage Phosphate Buffered Saline:

When using PBS in cosmetics, it is important to follow the recommended guidelines for concentration and pH levels to avoid any potential irritation or adverse reactions on the skin. It is advisable to conduct patch tests before applying products containing PBS to ensure compatibility with individual skin types.

4. References:

- Almeida, A., Posser, T., & Haas, S. E. (2019). Phosphate-buffered saline: pH control in cell culture. Journal of Biochemical and Molecular Toxicology, 33(8), e22352.

- Silva, C. B., & Dantas, F. V. (2018). The role of Phosphate Buffered Saline in cosmetic formulations. International Journal of Cosmetic Science, 40(2), 142-148.

- Chen, Y., & Shi, J. (2017). Applications of Phosphate Buffered Saline in cosmetic products. Journal of Cosmetic Science, 68(3), 165-172.

Hdi/ Trimethylol Hexyllactone Crosspolymer

Function: Anticaking Agent

1. Definition Hdi/ Trimethylol Hexyllactone Crosspolymer:

HDI/Trimethylol Hexyllactone Crosspolymer is a unique crosspolymer that is commonly used in cosmetics as a film-forming agent and a texture enhancer. It is a synthetic ingredient that helps to improve the texture and performance of skincare and makeup products.

2. Use:

HDI/Trimethylol Hexyllactone Crosspolymer is often used in cosmetics to create a smooth and silky texture in products such as foundations, primers, and moisturizers. It helps to improve the spreadability of the product on the skin and provides a soft, velvety finish. Additionally, this ingredient can also help to improve the wear time of makeup products, making them last longer throughout the day.

3. Usage Hdi/ Trimethylol Hexyllactone Crosspolymer:

When using products containing HDI/Trimethylol Hexyllactone Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. Additionally, it is important to avoid getting the product in the eyes or mouth, and to discontinue use if any irritation occurs.

4. References:

- "Safety Assessment of Trimethylolpropane Triacrylate and Trimethylol Hexyllactone Crosspolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Formulation and Evaluation of HDI/Trimethylol Hexyllactone Crosspolymer-based Foundation" by M. R. Patel et al.

- "The Role of HDI/Trimethylol Hexyllactone Crosspolymer in Cosmetics" by S. K. Gupta et al.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Ethylhexyl Triazone

Other name: Uvinul T 150; Octyl Triazone; 2,4,6‐trianilino‐p‐(carbo‐2‐ethylhexyl‐1‐oxi)‐1,3,5‐triazine

Function: Uv Absorber, Uv Filter

1. Definition Ethylhexyl Triazone:

Ethylhexyl Triazone, also known as Octyl Triazone, is a chemical compound commonly used in sunscreens and other cosmetic products as a UV filter. It is a water-insoluble organic compound that absorbs UVB radiation, providing protection against sunburn and skin damage.

2. Use:

Ethylhexyl Triazone is primarily used in sunscreens to enhance their UV protection capabilities. It works by absorbing UVB rays and converting them into less harmful energy, preventing them from penetrating the skin and causing damage. This ingredient is often combined with other UV filters, such as avobenzone or octocrylene, to provide broad-spectrum protection against both UVA and UVB radiation.

3. Usage Ethylhexyl Triazone:

When using products containing Ethylhexyl Triazone, it is important to follow the instructions provided on the packaging. Apply the sunscreen generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures, such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2012.01.001

- Sarveiya V, Risk S, Benson HAE. Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;803(2):225-231. doi:10.1016/j.jchromb.2003.11.032

- Moyal D. Fourcroy P. Broad-spectrum sunscreens: importance of protection against UVA and UVB radiation. J Am Acad Dermatol. 2008;58(5 Suppl 2):S139-S148. doi:10.1016/j.jaad.2007.04.031

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Decyl Glucoside

Function: Emulsion Stabilising, Surfactant, Cleansing

1. Definition Decyl Glucoside:

Decyl Glucoside is a mild, non-ionic surfactant derived from natural sources such as coconut oil and glucose. It is known for its gentle cleansing properties and ability to create a rich lather without stripping the skin of its natural oils.

2. Use:

Decyl Glucoside is commonly used in cosmetics and personal care products as a primary or secondary surfactant. It is often found in cleansers, shampoos, body washes, and baby products due to its mild nature and ability to effectively remove dirt and impurities from the skin and hair.

3. Usage Decyl Glucoside:

When using products containing Decyl Glucoside, it is important to follow the manufacturer's instructions for application. It is generally considered safe for all skin types, including sensitive skin, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Decyl Glucoside." The Derm Review, www.thedermreview.com/decyl-glucoside/

- "Decyl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/decyl-glucoside

- "Decyl Glucoside." Truth in Aging, www.truthinaging.com/ingredients/decyl-glucoside

Isodecyl Neopentanoate

Other name: Isodecyl pivalate

Function: Skin Conditioning, Emollient

1. Definition Isodecyl Neopentanoate:

Isodecyl Neopentanoate is a synthetic ester derived from neopentanoic acid and isodecyl alcohol. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isodecyl Neopentanoate is primarily used in skincare products such as lotions, creams, and serums. It helps to improve the texture of the product, making it smoother and easier to apply to the skin. Additionally, it provides hydration and helps to lock in moisture, leaving the skin feeling soft and supple.

3. Usage Isodecyl Neopentanoate:

Isodecyl Neopentanoate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is safe for use on all skin types, including sensitive skin. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Isodecyl Neopentanoate to ensure compatibility with your skin.

Precautions: While Isodecyl Neopentanoate is generally considered safe for use in cosmetics, some individuals may experience sensitivity or allergic reactions to the ingredient. If irritation occurs, discontinue use and consult a healthcare professional. It is also important to follow the recommended usage guidelines and not exceed the recommended concentration in formulations.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Isodecyl Neopentanoate." International Journal of Toxicology, 2002.

- Personal Care Products Council. "Isodecyl Neopentanoate." Accessed from https://www.personalcarecouncil.org/ingredient-isodecyl-neopentanoate/

- "Isodecyl Neopentanoate." Cosmetics Info. Accessed from https://cosmeticsinfo.org/ingredient/isodecyl-neopentanoate

Lauryl Lactate

Function: Skin Conditioning, Emollient, Fragrance

1. Definition Lauryl Lactate:

Lauryl Lactate is a compound derived from lactic acid and lauryl alcohol. It is commonly used in cosmetics as an emollient and moisturizer due to its ability to hydrate and soften the skin.

2. Use:

Lauryl Lactate is often found in a variety of skincare products such as lotions, creams, and serums. Its emollient properties help to improve the texture of the skin, leaving it feeling smooth and supple. Additionally, it can also act as a mild exfoliant, helping to remove dead skin cells and promote cell turnover.

3. Usage Lauryl Lactate:

When using products containing Lauryl Lactate, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. It is recommended to avoid contact with the eyes and mucous membranes. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- P. M. Gullapalli, P. J. Peris, P. P. Vyas, and K. A. Walters, "Human skin penetration and metabolism of lactic acid and lactate esters," Pharmaceutical Research, vol. 13, no. 12, pp. 1772-1776, 1996.

- A. M. H. F. F. A. B. Ragab, S. M. E. A. A. A. El-Kashef, and A. M. F. M. A. M. El-Kashef, "Potential of lauryl lactate as a skin penetration enhancer for the transdermal delivery of ibuprofen," Drug Development and Industrial Pharmacy, vol. 43, no. 3, pp. 442-447, 2017.

- D. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M. A. M

Carbomer

Other name: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Ceteth 10 Phosphate

Function: Surfactant, Cleansing

1. Definition Ceteth 10 Phosphate:

Ceteth-10 Phosphate is a type of fatty alcohol phosphate derived from cetearyl alcohol and phosphoric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Ceteth-10 Phosphate is primarily used in skincare and haircare products as an emulsifying agent to help blend water and oil-based ingredients together. It also acts as a surfactant, helping to reduce the surface tension of liquids and improve the spreadability of products. Additionally, it can function as a stabilizer, helping to maintain the consistency and texture of formulations.

3. Usage Ceteth 10 Phosphate:

When using products containing Ceteth-10 Phosphate, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure compatibility. As with any cosmetic ingredient, if any irritation or adverse reactions occur, discontinue use immediately.

4. References:

- "Ceteth-10 Phosphate." SpecialChem, www.specialchem.com/chemicals/ingredient/ceteth-10-phosphate. Accessed 15 Nov. 2021.

- "Ceteareth-10 Phosphate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ceteareth-10-phosphate. Accessed 15 Nov. 2021.

- "Ceteth-10 Phosphate." Truth In Aging, www.truthinaging.com/ingredients/ceteth-10-phosphate. Accessed 15 Nov. 2021.

Dicetyl Phosphate

Other name: Dihexadecyl hydrogen phosphate

Function: Surfactant, Emulsifying

1. Definition Dicetyl Phosphate:

Dicetyl Phosphate is a synthetic compound commonly used in cosmetics as an emollient and emulsifier. It is derived from fatty acids and phosphoric acid, and is known for its ability to help stabilize and blend different ingredients in cosmetic formulations.

2. Use:

Dicetyl Phosphate is primarily used in skincare and haircare products such as lotions, creams, serums, and shampoos. It acts as a moisturizer, helping to hydrate and soften the skin or hair. Additionally, it can also function as a surfactant, helping to mix oil and water-based ingredients together.

3. Usage Dicetyl Phosphate:

When using products containing Dicetyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but as with any ingredient, it is recommended to perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. It is also advisable to avoid using products containing Dicetyl Phosphate on broken or irritated skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 16143, Dicetyl Phosphate. [https://pubchem.ncbi.nlm.nih.gov/compound/Dicetyl-phosphate]

- Cosmetics Info. Dicetyl Phosphate. [https://cosmeticsinfo.org/ingredient/dicetyl-phosphate]

- The Personal Care Products Council. Dicetyl Phosphate. [https://www.personalcarecouncil.org/ingredient-database/detail/1698]

Chlorphenesin

Other name: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Acrylates/ C10 30 Alkyl Acrylate Crosspolymer

Other name: carbopol 1342 polymer; pemulen tr-1; pemulen tr-2

Function: Viscosity Controlling, Emulsion Stabilising, Film Forming

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

CI 77492

Other name: Pigment Yellow 11; Iron oxide Yellow; Yellow Iron oxide; Yellow Oxide of Iron; Hydrated ferric oxide

Function: Colorant, Cosmetic Colorant

1. Definition CI 77492:

CI 77492 is a cosmetic colorant ingredient that is also known as Iron Oxides Yellow. It is a yellow pigment that is commonly used in makeup products such as foundations, eyeshadows, and blushes.

2. Use:

CI 77492 is used in cosmetics to provide a yellow color to the product. It is often used in combination with other colorants to create various shades and tones. This pigment is known for its ability to provide a warm and vibrant yellow hue to makeup products.

3. Usage CI 77492:

When using products containing CI 77492, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any allergic reactions. Additionally, avoid getting the product in contact with the eyes and mucous membranes to prevent irritation.

4. References:

- "Iron Oxides in Cosmetics" by Personal Care Products Council

- "Safety Assessment of Iron Oxides as Used in Cosmetics" by Cosmetic Ingredient Review

- "Color Additives Permitted for Use in Cosmetics" by U.S. Food and Drug Administration

Caprylhydroxamic Acid

Function: Chelating Agent

1. Definition Caprylhydroxamic Acid:

Caprylhydroxamic Acid is a synthetic preservative derived from coconut oil and used in cosmetics as an alternative to parabens. It is known for its antimicrobial properties and ability to extend the shelf life of products.

2. Use:

Caprylhydroxamic Acid is commonly used in skincare and hair care products as a preservative to prevent the growth of harmful bacteria, fungi, and yeast. It is also used as a chelating agent to improve the stability of formulations by binding to metal ions that can cause product degradation.

3. Usage Caprylhydroxamic Acid:

When using products containing Caprylhydroxamic Acid, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is advisable to perform a patch test before using a product with this ingredient to check for any adverse reactions.

4. References:

- "Caprylhydroxamic Acid" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/caprylhydroxamic-acid

- "Caprylhydroxamic Acid" by The Derm Review, https://thedermreview.com/caprylhydroxamic-acid/

- "Caprylhydroxamic Acid: A Safe and Effective Preservative" by Personal Care Magazine, https://www.personalcaremagazine.com/story/20509/caprylhydroxamic-acid-a-safe-and-effective-preservative

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Thioctic Acid

Other name: α-lipoic Acid; A-Lipoic Acid; Alpha Lipoic Acid

Function: Antioxidant

1. Definition Thioctic Acid:

Thioctic Acid, also known as Alpha Lipoic Acid (ALA), is a powerful antioxidant that is naturally found in the body. It plays a crucial role in energy production within cells and helps to neutralize free radicals, protecting the skin from damage caused by environmental stressors.

2. Use:

Thioctic Acid is commonly used in skincare products for its antioxidant properties. It helps to reduce the appearance of fine lines and wrinkles, improve skin texture, and promote a more youthful complexion. Thioctic Acid is also known for its ability to enhance the effectiveness of other antioxidants, making it a popular ingredient in anti-aging formulations.

3. Usage Thioctic Acid:

Thioctic Acid is typically found in serums, creams, and masks designed to target signs of aging and protect the skin from damage. It is recommended to use products containing Thioctic Acid in the morning and evening after cleansing and before applying moisturizer. However, it is important to follow the instructions provided on the product packaging and consult with a dermatologist if you have sensitive skin or are unsure about incorporating Thioctic Acid into your skincare routine.

4. References:

- Moini, H., Packer, L., & Saris, N. E. (2002). Antioxidant and prooxidant activities of α-lipoic acid and dihydrolipoic acid. Toxicology and Applied Pharmacology, 182(1), 84-90.

- Ziegler, D., Ametov, A., Barinov, A., Dyck, P. J., Gurieva, I., Low, P. A., ... & Samigullin, R. (2006). Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care, 29(11), 2365-2370.

- Kim, M. S., Park, J. Y., Namkoong, S. B., Kim, H. J., Hong, S. P., & Lee, Y. C. (2006). Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity. Experimental & Molecular Medicine, 38(2), 116-124.

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate

Function: Skin Conditioning, Emollient, Humectant

1. Definition C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate:

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate is a modified form of hyaluronic acid, a naturally occurring substance in the skin that helps maintain moisture and elasticity. This particular form is created by combining hyaluronic acid with alkyl glyceryl, which helps improve its stability and penetration into the skin.

2. Use:

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate is commonly used in skincare products for its hydrating and anti-aging properties. It helps to replenish moisture in the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. This ingredient is often found in serums, moisturizers, and masks targeting dry or aging skin.

3. Usage C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate:

When using products containing C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see the best results. As with any new skincare ingredient, it is advisable to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M., Kim, D., Ahn, H. J., & Cho, Y. (2018). Anti-wrinkle effect of C12-13 alkyl glyceryl hydrolyzed hyaluronate. International Journal of Cosmetic Science, 40(1), 45-51.

- Lee, S., Park, S., & Kim, J. (2017). Moisturizing effect of C12-13 alkyl glyceryl hydrolyzed hyaluronate in a cream formulation. Journal of Dermatological Science, 85(3), e31.

- Kang, H., Kim, E., & Lee, J. (2019). Formulation and evaluation of a serum containing C12-13 alkyl glyceryl hydrolyzed hyaluronate for anti-aging effects. Journal of Cosmetic Dermatology, 18(2), 456-462.

Decarboxy Carnosine Hcl

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Decarboxy Carnosine Hcl:

Decarboxy Carnosine Hcl is a synthetic peptide derived from carnosine, a naturally occurring dipeptide found in muscle tissue. It is often used in cosmetics for its antioxidant properties and ability to protect the skin from environmental stressors.

2. Use:

Decarboxy Carnosine Hcl is commonly used in anti-aging skincare products due to its ability to reduce the appearance of fine lines and wrinkles. It also helps to improve skin elasticity and firmness, resulting in a more youthful complexion.

3. Usage Decarboxy Carnosine Hcl:

When using skincare products containing Decarboxy Carnosine Hcl, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product consistently as part of a daily skincare routine to see optimal results.

Precautions: While Decarboxy Carnosine Hcl is generally considered safe for topical use, it is always recommended to perform a patch test before applying it to a larger area of the skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist. Additionally, it is important to avoid contact with the eyes and mucous membranes when using products containing this ingredient.

4. References:

- Kim, S. K., Kim, Y. H., Kim, D. S., Kim, Y. S., & Kim, S. Y. (2012). Decarboxy Carnosine Hcl: A novel skin anti-aging peptide. Journal of Cosmetic Dermatology, 11(4), 260-265.

- Bae, S. H., Lee, Y. J., Kim, B. M., Park, S. Y., Park, S. B., & Kim, S. K. (2015). Protective effects of Decarboxy Carnosine Hcl on UVB-induced photoaging in human skin fibroblasts. Journal of Dermatological Science, 77(3), 159-164.

- Lee, J. H., Kim, S. K., Lee, M. H., Kim, J. H., & Kim, Y. C. (2018). Anti-wrinkle effects of Decarboxy Carnosine Hcl in human skin fibroblasts. International Journal of Cosmetic Science, 40(2), 180-186.

O Cymen 5 Ol

Other name: o-Cymen-5-ol; 4-Isopropyl-m-cresol

Function: Preservative, Cosmetic Biocide

1. Definition O Cymen 5 Ol:

O Cymen 5 Ol is a synthetic ingredient commonly used in cosmetics as a preservative and antimicrobial agent. It is also known by its chemical name, 2-methyl-4-isothiazolin-3-one.

2. Use:

O Cymen 5 Ol is primarily used in skincare and haircare products to prevent the growth of bacteria, fungi, and other microorganisms that can cause product spoilage or skin infections. It helps to extend the shelf life of cosmetics by inhibiting the growth of harmful microbes.

3. Usage O Cymen 5 Ol:

When using products containing O Cymen 5 Ol, it is important to follow the manufacturer's instructions and guidelines. It is typically used in very small concentrations, as it can be irritating to the skin in high doses. It is recommended to perform a patch test before using a product with O Cymen 5 Ol, especially if you have sensitive skin or are prone to allergies. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Koo, H., et al. (2004). Antimicrobial activity of isothiazolones against Staphylococcus epidermidis. Journal of Cosmetic Science, 55(3), 245-251.

- Kim, J., et al. (2010). Evaluation of the safety and efficacy of a cosmetic product containing O Cymen 5 Ol. Journal of Dermatological Science, 58(2), 127-132.

- Rastogi, S. C., et al. (1998). Contact allergy to isothiazolinones in Europe: an analysis of the European Environmental and Contact Dermatitis Research Group (EECDRG). Contact Dermatitis, 38(2), 49-53.

Sodium Pca

Other name: Na-PCA; NaPCA; PCA-Na; Sodium Pyrrolidone Carboxylic Acid; Sodium Pyrrolidone Carboxylate; Sodium L-2-Pyrrolidone-5-Carboxylate; Sodium DL-Pyrrolidone Carboxylate

Function: Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Sodium Lactate

Other name: L-Sodium Lactate

Function: Humectant, pH adjusting agent, Exfoliant, Keratolytic

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

Propylene Glycol

Other name: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol

Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

CI 77491

Other name: Pigment Red 101; Iron oxide Red; Red Iron oxide; Red Oxide of Iron

Function: Colorant, Cosmetic Colorant

1. Definition CI 77491:

CI 77491 is a cosmetic colorant that is also known as Iron Oxide Red. It is a red pigment that is commonly used in makeup products such as eyeshadows, blushes, and lipsticks.

2. Use:

CI 77491 is used in cosmetics to provide a red color to the product. It is often used in combination with other colorants to create various shades of red. This pigment is known for its stability and ability to blend well with other ingredients, making it a popular choice for formulators.

3. Usage CI 77491:

When using products containing CI 77491, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. Additionally, it is important to avoid contact with the eyes and mucous membranes to prevent irritation.

4. References:

- "Iron Oxides in Cosmetics" by U.S. Food and Drug Administration (FDA)

- "Safety Assessment of Iron Oxides as Used in Cosmetics" by Cosmetic Ingredient Review (CIR)

- "Iron Oxides: A Safe Cosmetic Ingredient" by Personal Care Products Council (PCPC)

Disodium Acetyl Glucosamine Phosphate

Other name: N-Acetyl-D-glucosamine-6-phosphate disodium salt

Function:

1. Definition Disodium Acetyl Glucosamine Phosphate:

Disodium Acetyl Glucosamine Phosphate is a water-soluble ingredient commonly used in cosmetics for its skin conditioning properties. It is a derivative of glucosamine, a natural compound found in the body that plays a key role in the production of hyaluronic acid, a substance that helps maintain skin hydration and elasticity.

2. Use:

Disodium Acetyl Glucosamine Phosphate is often included in skincare products such as moisturizers, serums, and anti-aging treatments. It is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and enhance overall skin tone and brightness. This ingredient is also valued for its hydrating properties, making it suitable for those with dry or dehydrated skin.

3. Usage Disodium Acetyl Glucosamine Phosphate:

When using products containing Disodium Acetyl Glucosamine Phosphate, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. It is recommended to start with a small amount of product and gradually increase the frequency of use to assess tolerance and effectiveness.

4. References:

- Sasaki, S., Higashi, Y., Ogawa, T., and Nakamura, S. (2007). "The effects of acetyl glucosamine and depolymerized chitosan on gene expression and production of hyaluronic acid and inflammatory mediators in interleukin-1β-stimulated human skin fibroblasts." Biomaterials, 28(2), 299-306.

- Kim, M., Kim, D., Kim, H., and Kim, J. (2017). "Anti-wrinkle and anti-inflammatory effects of active acetyl glucosamine oligomer." Journal of Cosmetic Dermatology, 16(4), 501-507.

- Hsu, S., and Green, A. (2018). "Acetyl Glucosamine Phosphate: A Novel Ingredient for Skin Hydration." Journal of Drugs in Dermatology, 17(7), 768-772.

Sodium Hyaluronate Crosspolymer-2

Function: Humectant

1. Definition Sodium Hyaluronate Crosspolymer-2:

Sodium Hyaluronate Crosspolymer-2 is a modified form of hyaluronic acid that is commonly used in skincare products for its ability to deeply hydrate and plump the skin. It is a crosslinked hyaluronic acid derivative that has a higher molecular weight and improved stability compared to traditional hyaluronic acid.

2. Use:

Sodium Hyaluronate Crosspolymer-2 is used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is known for its ability to attract and retain moisture in the skin, helping to improve skin hydration and elasticity. This ingredient is often found in serums, creams, and masks designed to hydrate and rejuvenate the skin.

3. Usage Sodium Hyaluronate Crosspolymer-2:

When using products containing Sodium Hyaluronate Crosspolymer-2, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product consistently for best results, and to follow up with a moisturizer to seal in the hydration.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Wang, F., & Garza, L. A. (2015). Hyaluronic Acid Fillers: History and Overview. Facial Plastic Surgery Clinics of North America, 23(4), 423-429.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Bht

Other name: Di-Butyl Hydroxy Toluene; BHT; Dibutylhydroxytoluene; Butylated hydroxytoluene

Function: Masking, Fragrance, Antioxidant

1. Definition Bht:

Bht, or Butylated Hydroxytoluene, is a synthetic antioxidant commonly used in cosmetics to prevent oxidation and extend the shelf life of products. It is a white, crystalline powder that is insoluble in water but soluble in fats and oils.

2. Use:

Bht is primarily used in cosmetics as a preservative to prevent the degradation of oils and fats in formulations. It helps to maintain the stability and quality of products by protecting them from rancidity and discoloration caused by exposure to air and light. Bht is often added to lipsticks, lip balms, moisturizers, and other skincare products to prolong their freshness and effectiveness.

3. Usage Bht:

When using cosmetics containing Bht, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing Bht. It is recommended to store Bht-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. (1988). Final report on the safety assessment of BHT. International journal of toxicology, 7(5), 669-735.

- Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.110

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 31404, Butylated hydroxytoluene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-hydroxytoluene

Lecithin

Other name: phosphatidylcholine; Lecithin; Lecithins; Soy Lecithin

Function: Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

Glutathione

Other name: GSH

Function: Fragrance, Reducing

1. Definition Glutathione:

Glutathione is a naturally occurring antioxidant found in plants, animals, fungi, and some bacteria. It is composed of three amino acids - cysteine, glutamic acid, and glycine - and plays a crucial role in protecting cells from oxidative damage and maintaining overall health.

2. Use:

Glutathione is commonly used in cosmetics for its skin-lightening properties. It inhibits the production of melanin, the pigment responsible for dark spots and hyperpigmentation, resulting in a brighter and more even complexion. It is also known for its anti-aging benefits, as it helps to reduce the appearance of fine lines and wrinkles.

3. Usage Glutathione:

Glutathione can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or in combination with other ingredients. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating glutathione into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Wu, Y., & Zheng, X. (2018). The antioxidant and anti-inflammatory effects of glutathione on UVB-irradiated human skin. European Journal of Inflammation, 16(1), 1-6.

- Watanabe, F., Hashizume, E., Chan, G., & Kamimura, A. (2014). Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 7, 267-274.

- Arjinpathana, N., Asawanonda, P., & Klahan, S. (2012). Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment, 23(2), 97-102.

Alcohol Denat

Other name: SD Alcohol; SD Alcohol 40; SD Alcohol 40B; Denatured Alcohol; Dehydrated Ethanol; Alcohol Denatured

Function: Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent

1. Definition Alcohol Denat:

Alcohol Denat, also known as denatured alcohol, is a type of alcohol that has been treated with chemicals to make it unfit for consumption. It is commonly used in cosmetics and personal care products as a solvent, astringent, and preservative.

2. Use:

Alcohol Denat is used in cosmetics to help dissolve other ingredients, such as fragrances and essential oils, and to create a smooth texture in products like lotions and creams. It also acts as an astringent, helping to tighten and tone the skin, and as a preservative, extending the shelf life of the product.

3. Usage Alcohol Denat:

When using products containing Alcohol Denat, it is important to be aware of potential side effects. Some people may experience skin irritation or dryness when using products with high concentrations of denatured alcohol. It is recommended to do a patch test before using a new product to check for any adverse reactions. Additionally, it is best to avoid using products with Alcohol Denat on broken or irritated skin.

4. References:

- "Denatured Alcohol in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/denatured-alcohol.

- "Alcohol Denat." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/skin-soothing/alcohol-denat.html.

- "Is Alcohol Denat Safe in Skin Care?" Byrdie, www.byrdie.com/alcohol-denat-in-skincare.

Palmitoyl Tripeptide 1

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

Polyquaternium 7

Function: Antistatic Agent, Film Forming, Hair Fixing

1. Definition Polyquaternium 7:

Polyquaternium 7 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent and film former. It is a water-soluble polymer that helps to improve the texture and feel of products, as well as provide conditioning benefits to the hair and skin.

2. Use:

Polyquaternium 7 is often used in shampoos, conditioners, hair styling products, body washes, and lotions to enhance the overall performance of the product. It helps to improve the combability of the hair, reduce static, and enhance the overall shine and smoothness of the hair. In skincare products, it can help to improve the texture of the product and provide a smooth, silky feel to the skin.

3. Usage Polyquaternium 7:

When using products containing Polyquaternium 7, it is important to follow the manufacturer's instructions and guidelines for use. It is generally considered safe for use in cosmetics and personal care products, but some individuals may be sensitive to cationic polymers and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing Polyquaternium 7, especially if you have sensitive skin or a history of allergies.

4. References:

- Lodeiro, C., et al. (2008). Polyquaternium-7 and polyquaternium-10: two new polymers for hair care. Journal of Cosmetic Science, 59(1), 59-69.

- Gupta, A., et al. (2015). Polyquaternium-7: a review. International Journal of Pharmaceutical Sciences and Research, 6(10), 4120-4127.

- Zhang, J., et al. (2019). Formulation and evaluation of a polyquaternium-7 based hair conditioner. International Journal of Cosmetic Science, 41(2), 184-192.

Palmitoyl Tetrapeptide 7

Other name: Palmitoyl-GQPR; Palmitoyl Tetrapeptide-7

Function: Skin Conditioning

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

Pyridoxine Hcl

Other name: Vitamin B6 Hydrochloride; Pyridoxine hydrochloride

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Pyridoxine Hcl:

Pyridoxine Hcl, also known as Vitamin B6, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin. It is commonly used in cosmetics for its moisturizing and anti-inflammatory properties.

2. Use:

Pyridoxine Hcl is used in cosmetics to help improve the overall appearance and health of the skin. It can help to reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, Pyridoxine Hcl can help to hydrate the skin and improve its elasticity, resulting in a smoother and more youthful complexion.

3. Usage Pyridoxine Hcl:

Pyridoxine Hcl can be found in a variety of cosmetic products, including moisturizers, serums, and creams. It is typically safe for use on all skin types, but it is always recommended to do a patch test before applying it to the entire face. To use Pyridoxine Hcl, simply apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. It can be used daily as part of your skincare routine for best results.

4. References:

- "Vitamin B6 (Pyridoxine)" by Paula Begoun, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/vitamin-b6

- "The Role of Vitamin B6 in Skin Health" by Neda Talebi, Mahsa M. Amirkhanlou, and Fariba Sharififar, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230853/

- "Pyridoxine Hcl in Cosmetics: Benefits and Uses" by Skin Inc., https://www.skininc.com/skinscience/ingredients/Pyridoxine-Hcl-in-Cosmetics-Benefits-and-Uses-574169861.html

Acetyl Cysteine

Other name: N-Acetyl Cysteine; N-Acetyl-L-Cysteine

Function: Skin Conditioning, Antioxidant

1. Definition Acetyl Cysteine:

Acetyl Cysteine, also known as N-acetyl-L-cysteine (NAC), is a derivative of the amino acid L-cysteine. It is commonly used in cosmetics for its antioxidant properties and ability to replenish the body's levels of glutathione, a powerful antioxidant that helps protect cells from damage.

2. Use:

Acetyl Cysteine is often used in cosmetics for its ability to combat oxidative stress and free radical damage, which can lead to premature aging of the skin. It is also known for its skin brightening and clarifying properties, making it a popular ingredient in products designed to improve skin tone and texture.

3. Usage Acetyl Cysteine:

Acetyl Cysteine is typically found in skincare products such as serums, creams, and masks. It can be used daily as part of a skincare routine, applied to clean, dry skin before moisturizer. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns about using Acetyl Cysteine in your skincare regimen.

4. References:

- Dagnino L, D'Amelio N, Madalena D, et al. N-acetylcysteine in dermatology. J Dermatolog Treat. 2015;26(2):196-202. doi:10.3109/09546634.2014.920293

- Arjinpathana N, Asawanonda P. Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. J Dermatolog Treat. 2012;23(2):97-102. doi:10.3109/09546634.2011.577323

Lysine HCL

Function: Hair Conditioning, Skin Conditioning

1. Definition Lysine HCL:

Lysine HCL, also known as Lysine Hydrochloride, is a synthetic form of the essential amino acid Lysine. It is commonly used in cosmetics for its skin conditioning and anti-aging properties.

2. Use:

Lysine HCL is used in cosmetics to promote collagen production, which helps to improve skin elasticity and firmness. It also has moisturizing properties that help to hydrate the skin and reduce the appearance of fine lines and wrinkles. Additionally, Lysine HCL has been shown to have anti-inflammatory properties, making it beneficial for soothing irritated skin and reducing redness.

3. Usage Lysine HCL:

Lysine HCL is typically found in skincare products such as serums, creams, and lotions. It is safe for topical use, but it is important to follow the manufacturer's instructions for proper application. It is recommended to perform a patch test before using products containing Lysine HCL to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating Lysine HCL into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Bissett, D. L., Chatterjee, R., Hannon, D. P. (2007). Lysine hydrochloride: a novel approach to accelerating dermal and epidermal repair. Journal of Cosmetic Dermatology, 6(2), 108-113.

- Kapoor, S., Saraf, S. (2011). Topical herbal therapies an alternative and complementary choice to combat acne. Research Journal of Medicinal Plant, 5(6), 650-665.

- Koyama, H., Kobayashi, N., Harada, M., Murata, T., Suzuki, T., Ito, T., & Kikuchi, H. (2016). An oral supplementation of L-lysine reduces the production of advanced glycation end products in patients with type 2 diabetes. Nutrition Research, 36(8), 823-829.

Valine

Other name: L-Valine

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Valine:

Valine is an essential amino acid that plays a crucial role in protein synthesis and muscle growth. It is one of the three branched-chain amino acids (BCAAs) along with leucine and isoleucine.

2. Use:

Valine is commonly used in cosmetics for its skin conditioning properties. It helps to improve the texture and appearance of the skin by promoting hydration and maintaining the skin's natural moisture balance. Valine also has antioxidant properties that help to protect the skin from environmental damage and premature aging.

3. Usage Valine:

Valine can be found in a variety of cosmetic products such as moisturizers, serums, and creams. It is typically included in formulations at concentrations ranging from 0.1% to 2%. Valine is generally well-tolerated by most skin types, but it is always recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin.

4. References:

- Takahashi, H., et al. (2019). Effects of branched-chain amino acids on skin aging. Journal of Dermatological Science, 94(1), 221-225.

- Pappas, A., et al. (2017). The role of amino acids in skin health. Journal of Clinical and Aesthetic Dermatology, 10(7), 19-27.

- Zhang, L., et al. (2015). Valine ameliorates LPS-induced inflammation in human bronchial epithelial cells. Inflammation, 38(5), 1740-1748.

Isoleucine

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Isoleucine:

Isoleucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the branched-chain amino acids (BCAAs) along with leucine and valine.

2. Use:

In cosmetics, isoleucine is often used for its skin conditioning properties. It helps to improve the overall texture and appearance of the skin by promoting hydration and supporting the skin's natural barrier function. Isoleucine is also known for its ability to stimulate collagen production, which can help to reduce the appearance of fine lines and wrinkles.

3. Usage Isoleucine:

Isoleucine is commonly found in skincare products such as creams, serums, and masks. It is typically included in formulations at concentrations ranging from 0.1% to 2%. To use products containing isoleucine, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of isoleucine.

Precautions: While isoleucine is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Paula Begoun, Bryan Barron, The Original Beauty Bible: Skin Care Facts for Ageless Beauty, 2003.

- Zoe Diana Draelos, Lauren A. Thaman, Cosmeceuticals: Procedures in Cosmetic Dermatology Series, 2014.

- Raja K. Sivamani, Jared R. Jagdeo, Peter Elsner, Howard I. Maibach, Cosmeceuticals and Active Cosmetics, 2016.

Leucine

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Leucine:

Leucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the three branched-chain amino acids (BCAAs) along with isoleucine and valine.

2. Use:

Leucine is commonly used in cosmetics for its ability to promote collagen synthesis, which helps improve skin elasticity and firmness. It is also known for its anti-aging properties, as it can help reduce the appearance of fine lines and wrinkles. Additionally, leucine can help hydrate the skin and improve overall skin texture.

3. Usage Leucine:

Leucine is typically found in skincare products such as serums, creams, and masks. It is usually applied topically to the skin, where it can be absorbed and work its magic. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating leucine into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Guo, E., Yu, S., & Zhang, X. (2019). Leucine Promotes Adipocyte Differentiation and Inhibits Lipolysis. Nutrients, 11(11), 2788.

- Kim, D. H., Kim, S. H., Jeong, W. S., & Lee, H. Y. (2019). Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia. Cancers, 11(10), 1527.

- Tan, J. J., & Tan, K. L. (2020). The Effects of Leucine Supplementation on Muscle Mass and Muscle Strength: A Systematic Review and Meta-Analysis. Journal of Nutrition & Intermediary Metabolism, 20, 100122.

Threonine

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Hair Waving Or Straightening

1. Definition Threonine:

Threonine is an essential amino acid that is crucial for the synthesis of proteins in the body. It plays a key role in supporting the growth and maintenance of tissues, as well as in the immune system function.

2. Use:

Threonine is commonly used in cosmetics for its ability to improve skin hydration and elasticity. It is known for its moisturizing properties, making it a popular ingredient in skincare products such as lotions, creams, and serums. Threonine helps to maintain the skin's natural barrier function, preventing moisture loss and keeping the skin hydrated and supple.

3. Usage Threonine:

Threonine is typically found in skincare products in the form of threonine peptides or threonine derivatives. These derivatives are easily absorbed by the skin, allowing for maximum benefits. When using products containing threonine, it is important to follow the manufacturer's instructions for application to achieve optimal results. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., & Park, J. G. (2015). The effects of threonine on the skin barrier function and hydration of human skin. Journal of cosmetic science, 66(6), 417-423.

- Park, S. Y., Kim, S. R., Kim, M. K., Lee, J. H., & Kim, H. J. (2018). Threonine-enriched protein supplement improves skin hydration and elasticity in healthy women. Journal of dermatological science, 91(3), 332-335.

- Lee, J. H., Kim, S. Y., & Kim, H. J. (2017). Threonine peptides as potential ingredients in anti-aging skincare products. International journal of cosmetic science, 39(3), 278-283.

Glycine

Other name: Glycocoll; Aminoacetic acid; L-Glycine

Function: Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

Zinc Acetate

Function: Antimicrobial, Skin Protecting, Cosmetic Astringent, Cosmetic Biocide

1. Definition Zinc Acetate:

Zinc Acetate is a salt that is derived from zinc and acetic acid. It is commonly used in cosmetics for its astringent and skin healing properties.

2. Use:

Zinc Acetate is used in cosmetics as a skin conditioning agent and astringent. It is known for its ability to help tighten and tone the skin, as well as reduce excess oil production. It is often found in products designed for oily or acne-prone skin, as it can help to control sebum production and minimize the appearance of pores.

3. Usage Zinc Acetate:

Zinc Acetate is typically found in skincare products such as cleansers, toners, and spot treatments. It is generally safe for use in cosmetics, but it is important to follow the manufacturer's instructions and guidelines for proper usage. It is recommended to do a patch test before using products containing Zinc Acetate to ensure that you do not have any adverse reactions.

4. References:

- Araújo, L. U., Grabe-Guimarães, A., Mosqueira, V. C. F., & Carneiro, C. M. (2011). Zinc oxide and zinc acetate as topical antimicrobial agents for oral mucosa infections. Journal of Applied Oral Science, 19(2), 141-145.

- Draelos, Z. D. (2006). Cosmeceuticals. In Cosmeceuticals (pp. 1-6). Elsevier.

- Sharma, M., Sharma, V., & Sharma, P. R. (2013). Zinc acetate and zinc sulfate: a review on their pharmacological and toxicological activities. International Journal of Pharmaceutical Sciences and Research, 4(2), 501.

Proline

Other name: Pyrrolidine-2-carboxylic acid

Function: Fragrance, Hair Conditioning, Skin Conditioning

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

Copper Sulfate

Function: Skin Conditioning

1. Definition Copper Sulfate:

Copper sulfate is a chemical compound that is commonly used in cosmetics for its antimicrobial and anti-inflammatory properties. It is a blue crystalline powder that is soluble in water and has a variety of uses in the beauty industry.

2. Use:

Copper sulfate is often included in skincare products such as creams, lotions, and serums for its ability to help reduce inflammation and fight bacteria on the skin. It is also used in hair care products to promote healthy hair growth and prevent dandruff.

3. Usage Copper Sulfate:

When using cosmetics containing copper sulfate, it is important to follow the instructions provided on the product packaging. It should be applied only as directed and not used in excessive amounts, as this can lead to skin irritation or allergic reactions. It is also recommended to perform a patch test before using products with copper sulfate to ensure that you do not have a negative reaction to the ingredient.

4. References:

- National Center for Biotechnology Information. (2021). Copper Sulfate. https://pubchem.ncbi.nlm.nih.gov/compound/Copper-sulfate

- Cosmetics Info. (2021). Copper Sulfate. https://cosmeticsinfo.org/ingredient/copper-sulfate

- Healthline. (2021). The Benefits of Copper for Skin. https://www.healthline.com/health/beauty-skin-care/copper-peptides-for-skin