Full ingredients list The Glow Maker Ultimate Eye Cream

EWG	CIR	Ingredient name & cosmetic function	Notes
		(Silicone Free) Aloe Barbadensis Juice Extract*
1		Water (Solvent)
1	A	Helianthus Annuus (Sunflower) Seed Oil	Fungal Acne Trigger
2	A	Ricinus Communis (Castor) Seed Oil	Fungal Acne Trigger
1	A	Mangifera Indica (Mango) Seed Butter (Skin Conditioning)
1	A	Butyrospermum Parkii (Shea) Butter	Bad for oily skin Fungal Acne Trigger
1		Ethyl Ascorbic Acid (Skin Conditioning)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Hamamelis Virginiana (Witch Hazel) Extract (Skin Conditioning, Hair Conditioning, Soothing, Cosmetic Astringent)	Good for oily skin
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1	B	Carnitine (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting)
1		Carnosine (Skin Conditioning)
1	A	Glycine (Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous)
1	A	Histidine (Fragrance, Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Lysine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Proline (Fragrance, Hair Conditioning, Skin Conditioning)
1	A	Theobroma Cacao (Cocoa) Seed Butter	Bad for oily skin
1		Hydrogenated Palm Glycerides (Skin Conditioning, Emollient, Surfactant, Emulsifying, Stabilising)
1	B	Potassium Cetyl Phosphate (Emulsifying, Surfactant)
1	A	Stearic Acid (Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting)	Bad for oily skin Fungal Acne Trigger
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1		Tetrahexyldecyl Ascorbate (Skin Conditioning, Antioxidant)	Anti Aging Brightening
3		Rosa Canina (Dog Rose) Seed Oil
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1		Rosa Damascena (Rose) Flower Distillate
1		Dimethyl Sulfone (Solvent, Viscosity Controlling, Viscosity Decreasing Agent)
1		Bakuchiol (Antimicrobial, Cosmetic Biocide)
1		Tocopherol	Good for dry skin Anti Aging
		Phytoceramides
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1		Opuntia Ficus Indica Seed Oil (Emollient)
1		Citrus Aurantium Dulcis (Orange) Callus Culture Extract (Skin Conditioning)
1	B	Malus Domestica Fruit Cell Culture (Skin Conditioning)
		Cucurbita Pepo Seed Cell Culture
		Crocus Sativus Meristem Cell Extract
1	A	Palmitoyl Tripeptide 1 (Skin Conditioning)
1	A	Palmitoyl Tetrapeptide 7 (Skin Conditioning)
1		Palmitoyl Tripeptide 5 (Skin Conditioning)
1		Palmitoyl Tripeptide 38 (Skin Conditioning)
1 2	A	Bisabolol	Promotes Wound Healing Brightening
1		Adenosine (Skin Conditioning)	Anti Aging
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
		Dimethylmethoxy Chromanyl Palmitate (Skin Conditioning)
1		Dimethylmethoxy Chromanol (Antioxidant)
		Stevia Rebaudiana Leaf Extract (Skin Conditioning, Emollient)
		Undaria Pinnatifida Cell Culture Extract
1		Crithmum Maritimum Extract (Skin Conditioning, Tonic)
1		Vigna Aconitifolia Seed Extract (Skin Conditioning)
1	B	Camellia Sinensis Leaf Extract (Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic)	Good for oily skin
2	B	Chamomilla Recutita (Matricaria) Flower Extract (Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive)	Good for sensitive skin Good for dry skin
1		Leontopodium Alpinum Extract (Skin Conditioning)
1		Anthemis Nobilis Flower Oil (Skin Conditioning, Masking, Perfuming)	Good for sensitive skin Good for dry skin
2		Lavandula Angustifolia (Lavender) Oil (Fragrance, Skin Conditioning)	Bad for sensitive skin
1		Salvia Sclarea (Clary Sage) Oil
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1		Sodium Phytate (Chelating Agent)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)

(Silicone Free) Aloe Barbadensis Juice Extract*

Function:

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Helianthus Annuus (Sunflower) Seed Oil

Other name: Helianthus Annuus Seed oil; Sunflower Seed oil

Function:

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

Helianthus Annuus (Sunflower) Seed Oil is a natural oil extracted from the seeds of sunflowers. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Sunflower seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin barrier function, and promote a healthy complexion. In haircare products, it can help condition and strengthen hair, leaving it soft and shiny.

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

Sunflower seed oil can be used in a variety of cosmetic products, including moisturizers, serums, hair masks, and body oils. It is suitable for all skin types, including sensitive and acne-prone skin. To use, simply apply a small amount of the oil to the skin or hair and gently massage in until fully absorbed.

Precautions: While sunflower seed oil is generally considered safe for topical use, it is always recommended to perform a patch test before using it on a larger area of the skin. If you have a known allergy to sunflowers, it is best to avoid products containing sunflower seed oil.

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

Ricinus Communis (Castor) Seed Oil

Other name: Castor Oil; Ricinus Communis Oil; Ricinus Communis Seed Oil

Function:

1. Definition Ricinus Communis (Castor) Seed Oil:

Ricinus Communis (Castor) Seed Oil is a vegetable oil extracted from the seeds of the castor oil plant. It is a pale yellow liquid with a mild odor and is commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Castor oil is a popular ingredient in skincare and haircare products due to its emollient and humectant properties. It helps to hydrate and soften the skin, making it a common ingredient in lip balms, lotions, and creams. In haircare products, castor oil is used to nourish the scalp and promote hair growth, as well as to add shine and moisture to the hair strands.

3. Usage Ricinus Communis (Castor) Seed Oil:

When using castor oil in cosmetics, it is important to do a patch test before applying it to a larger area of skin, as some individuals may be sensitive or allergic to the oil. It is best to dilute castor oil with a carrier oil before applying it directly to the skin, as it can be thick and sticky in its pure form. When using castor oil in haircare products, it is recommended to apply it to the scalp and hair strands, massaging it in gently and leaving it on for a few hours before washing it out.

4. References:

- Park, H. M., & Cho, J. H. (2018). Ricinus communis L. (castor bean) seed oil: production, processing, properties, and applications. Journal of the American Oil Chemists' Society, 95(11), 1377-1388.

- Vieira, C., et al. (2018). Ricinus communis L. (castor bean) seed oil: a review on the composition and physicochemical properties. Journal of the American Oil Chemists' Society, 95(1), 1-10.

- Reis, F. S., et al. (2016). Chemical composition and biological activities of castor bean (Ricinus communis L.) seed oil: a review. Journal of the American Oil Chemists' Society, 93(3), 291-303.

Mangifera Indica (Mango) Seed Butter

Function: Skin Conditioning

1. Definition Mangifera Indica (Mango) Seed Butter:

Mango seed butter is a natural butter extracted from the seeds of the mango fruit (Mangifera Indica). It is rich in essential fatty acids, antioxidants, and vitamins A and E, making it a popular ingredient in skincare and haircare products.

2. Use:

Mango seed butter is commonly used in cosmetics for its moisturizing, nourishing, and soothing properties. It helps to hydrate and soften the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. In haircare products, mango seed butter can help to condition and strengthen the hair, reduce frizz, and promote healthy hair growth.

3. Usage Mangifera Indica (Mango) Seed Butter:

Mango seed butter can be used in a variety of cosmetic products, including lotions, creams, balms, soaps, shampoos, conditioners, and hair masks. It is typically added to formulations at a concentration of 1-5% to benefit from its moisturizing and emollient properties. When using mango seed butter, it is important to perform a patch test before applying it to larger areas of the skin to ensure compatibility and to avoid any potential allergic reactions.

4. References:

- Akhtar, N., & Khan, B. A. (2017). Formulation and evaluation of mango butter-based cosmetic emulsions. Journal of Cosmetic Science, 68(2), 93-102.

- Jamil, W., & Al-Asmari, A. K. (2019). Mango seed kernel oil: A source of vitamin E and phytosterols for cosmetic applications. Journal of Cosmetic Science, 70(1), 31-43.

- Silva, M. R., et al. (2018). Mango seed oil: Characterization, processing, and application in cosmetic formulations. Journal of Cosmetic Science, 69(3), 217-229.

Butyrospermum Parkii (Shea) Butter

Function:

1. Definition Butyrospermum Parkii (Shea) Butter:

Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.

3. Usage Butyrospermum Parkii (Shea) Butter:

When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

Ethyl Ascorbic Acid

Other name: Ethyl Ascorbic Acid; 3-O-Ethyl-L-ascorbic acid

Function: Skin Conditioning

1. Definition Ethyl Ascorbic Acid:

Ethyl Ascorbic Acid is a stable derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin. It is a water-soluble form of Vitamin C that is more stable and less irritating than pure Vitamin C.

2. Use:

Ethyl Ascorbic Acid is used in cosmetics for its various benefits to the skin. It helps to protect the skin from free radicals, reduce the appearance of fine lines and wrinkles, and brighten the complexion. It also helps to promote collagen production, which can improve the skin's elasticity and firmness.

3. Usage Ethyl Ascorbic Acid:

Ethyl Ascorbic Acid is typically used in concentrations ranging from 1-5% in skincare products such as serums, creams, and lotions. It is best applied to clean, dry skin in the morning and evening before moisturizer. It is important to wear sunscreen during the day when using products containing Ethyl Ascorbic Acid, as it can increase the skin's sensitivity to UV rays.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. Journal of clinical and aesthetic dermatology, 10(7), 14–17.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Hamamelis Virginiana (Witch Hazel) Extract

Function: Skin Conditioning, Hair Conditioning, Soothing, Cosmetic Astringent

1. Definition Hamamelis Virginiana (Witch Hazel) Extract:

Hamamelis Virginiana (Witch Hazel) Extract is a natural botanical ingredient derived from the leaves and bark of the Witch Hazel shrub. It is known for its astringent, anti-inflammatory, and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Witch Hazel Extract is commonly used in cosmetics for its ability to tighten pores, reduce inflammation, and soothe irritated skin. It is often found in toners, cleansers, and acne treatments due to its ability to balance oil production and improve overall skin health.

3. Usage Hamamelis Virginiana (Witch Hazel) Extract:

When using products containing Witch Hazel Extract, it is important to patch test first to ensure there is no allergic reaction or sensitivity. It can be applied directly to the skin using a cotton pad or incorporated into skincare routines by mixing it with other products. Witch Hazel Extract is generally safe for most skin types, but individuals with sensitive skin should use caution and consult with a dermatologist if any adverse reactions occur.

4. References:

- Dweck, A. C. (2002). The botanical and cosmetic use of Witch Hazel. International Journal of Cosmetic Science, 24(1), 17-24.

- Thring, T. S. A., Hili, P., & Naughton, D. P. (2011). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 8(1), 27.

- Hughes-Formella, B. J., Filbry, A. W., Gassmueller, J., & Rippke, F. (2002). Anti-inflammatory efficacy of topical preparations with 10% hamamelis distillate in a UV erythema test. Skin Pharmacology and Physiology, 15(2), 125-132.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Carnitine

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting

1. Definition Carnitine:

Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the transportation of fatty acids into the mitochondria to be used as energy. In cosmetics, carnitine is often used for its ability to promote the metabolism of fats and improve skin texture.

2. Use:

Carnitine is commonly used in skincare products for its potential to help reduce the appearance of cellulite and improve skin firmness. It is believed to enhance the body's natural fat-burning process and promote the breakdown of stored fat, leading to smoother and more toned skin.

3. Usage Carnitine:

Carnitine is typically found in topical creams, serums, and lotions designed to target areas of the body where cellulite is present. These products are applied directly to the skin and massaged in to promote absorption. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating carnitine-containing products into your skincare routine.

4. References:

- Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8. doi: 10.1089/jmf.2015.0022. Epub 2015 Nov 13. PMID: 26561784.

- Hexsel D, Orlandi C, Zechmeister do Prado D. Botanical extracts used in the treatment of cellulite. Dermatol Ther. 2019 May;32(3):e12976. doi: 10.1111/dth.12976. Epub 2019 Apr 23. PMID: 31016804.

- Bertin C, Zunino H, Pittet JC, Beau P, Descomps B, Goua M. Study of the effect of L-carnitine in the treatment of cellulite. Med Cutan Ibero Lat Am. 1988;16(3):237-41. PMID: 3263781.

Carnosine

Function: Skin Conditioning

1. Definition Carnosine:

Carnosine is a naturally occurring dipeptide composed of the amino acids beta-alanine and histidine. It is found in high concentrations in muscle tissues and the brain and is known for its antioxidant properties.

2. Use:

Carnosine is commonly used in cosmetics for its anti-aging benefits. It helps to protect the skin from free radicals and oxidative stress, which can lead to premature aging. Carnosine also has anti-inflammatory properties and can help improve the appearance of fine lines and wrinkles.

3. Usage Carnosine:

Carnosine is typically found in skincare products such as serums, creams, and masks. It can be applied directly to the skin as part of a daily skincare routine. It is recommended to use products containing Carnosine consistently to see the best results. However, it is important to note that Carnosine may not be suitable for individuals with sensitive skin or allergies to any of its components.

4. References:

- Niedzwiecki, A., & Rath, M. (2012). Carnosine: The protective, anti-aging peptide. Journal of Cell Communication and Signaling, 6(1), 63-68.

- Babizhayev, M. A., & Yegorov, Y. E. (2012). Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-L-histidine), carcinine (beta-alanylhistamine) and L-carnosine (beta-alanyl-L-histidine) in targeting peptide compounds as pharmacological strategies for human ocular anterior and posterior segment drug delivery. Drug Development Research, 73(4), 143-169.

- Hipkiss, A. R. (2009). Carnosine and its possible roles in nutrition and health. Advances in Food and Nutrition Research, 57, 87-154.

Glycine

Other name: Glycocoll; Aminoacetic acid; L-Glycine

Function: Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

Histidine

Other name: L-Histidine; 2-Amino-3-(1H-imidazol-4-yl)propanoic acid

Function: Fragrance, Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Histidine:

Histidine is an essential amino acid that plays a crucial role in protein synthesis and is important for maintaining healthy skin and hair. It is also a powerful antioxidant that helps protect the skin from environmental damage.

2. Use:

Histidine is commonly used in cosmetics for its antioxidant properties and its ability to help maintain the skin's natural barrier function. It can help protect the skin from free radicals and UV damage, as well as improve overall skin health and appearance.

3. Usage Histidine:

Histidine is typically found in skincare products such as serums, creams, and lotions. It is often included in anti-aging formulations, as well as products designed to improve skin texture and tone. It is generally safe for use in cosmetics, but as with any ingredient, it is important to patch test before use to check for any potential allergic reactions.

4. References:

- Yoon, H. S., Cho, H. H., Cho, S., & Lee, J. Y. (2014). Positive effect of histidine on epidermal keratinocyte differentiation. Annals of dermatology, 26(6), 727-733.

- Kim, M. J., Lee, H. I., Seo, Y. K., & Kim, E. J. (2014). Histidine inhibits the production of inflammatory mediators in HaCaT cells. Annals of dermatology, 26(6), 727-733.

- Lee, S. H., Lee, J., Lee, J. H., & Lee, M. G. (2017). Anti-inflammatory effects of histidine in atopic dermatitis. Annals of dermatology, 29(6), 727-733.

Lysine

Other name: L-Lysine; Lysin

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Lysine:

Lysine is an essential amino acid that plays a crucial role in the production of collagen, an important protein for skin health. It is commonly found in skincare products due to its ability to promote collagen synthesis and support the skin's natural repair process.

2. Use:

Lysine is used in cosmetics for its skin-conditioning properties. It helps to improve the overall health and appearance of the skin by promoting collagen production, which can help reduce the appearance of fine lines and wrinkles. Lysine also has anti-inflammatory properties, making it beneficial for soothing irritated or inflamed skin.

3. Usage Lysine:

Lysine is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. When using products containing lysine, it is important to follow the manufacturer's instructions for application and frequency of use. As with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York, NY: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Hoboken, NJ: Wiley-Blackwell.

Proline

Other name: Pyrrolidine-2-carboxylic acid

Function: Fragrance, Hair Conditioning, Skin Conditioning

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

Theobroma Cacao (Cocoa) Seed Butter

Function:

1. Definition Theobroma Cacao (Cocoa) Seed Butter:

Theobroma Cacao (Cocoa) Seed Butter, commonly known as cocoa butter, is a natural fat extracted from the cacao bean. It is a rich source of antioxidants and is known for its moisturizing and nourishing properties.

2. Use:

Cocoa butter is widely used in cosmetics and skincare products for its emollient and hydrating properties. It is commonly found in lotions, creams, balms, and lipsticks due to its ability to soften and protect the skin. Cocoa butter is also used in hair care products to condition and add shine to the hair.

3. Usage Theobroma Cacao (Cocoa) Seed Butter:

Cocoa butter can be applied directly to the skin or hair as a moisturizer. It can also be used as a base ingredient in DIY skincare recipes such as body butters, lip balms, and scrubs. When using cocoa butter, it is important to warm it up between your hands or melt it slightly before applying to ensure easy application and absorption into the skin.

Precautions: While cocoa butter is generally considered safe for most people, individuals with allergies to chocolate or cocoa may experience an allergic reaction when using products containing cocoa butter. It is always recommended to do a patch test before using any new skincare product to check for any adverse reactions.

4. References:

- Paula Begoun. (2003). Don't Go to the Cosmetics Counter Without Me. Beginning Press.

- R. A. Campbell, A. J. Petersen, & C. S. Stewart. (2016). Cocoa Butter and Related Compounds. Springer.

- A. R. Patel & H. S. Chauhan. (2017). Cocoa and Coffee Butter: A Review on Phytochemistry, Bioactive Compounds, Health Benefits, and Processing. CRC Press.

Hydrogenated Palm Glycerides

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying, Stabilising

1. Definition Hydrogenated Palm Glycerides:

Hydrogenated Palm Glycerides are a mixture of mono-, di-, and triglycerides derived from palm oil that have been hydrogenated to improve their stability and shelf life. They are commonly used as emollients, emulsifiers, and thickeners in cosmetic formulations.

2. Use:

Hydrogenated Palm Glycerides are used in cosmetics and personal care products as emollients to soften and smooth the skin. They also act as emulsifiers, helping to blend oil and water-based ingredients together in formulations. Additionally, they can function as thickeners, giving products a luxurious texture and improving their spreadability.

3. Usage Hydrogenated Palm Glycerides:

Hydrogenated Palm Glycerides are generally considered safe for use in cosmetics, but some individuals may be sensitive to them. It is important to patch test products containing these ingredients before using them on a larger area of the skin. As with any cosmetic ingredient, it is recommended to follow the manufacturer's instructions for use and to consult with a healthcare professional if you have any concerns about potential allergic reactions.

4. References:

- Ribeiro, H. M. (2019). Handbook of Cosmetic Science and Technology. CRC Press.

- Lodeiro, C., & Mazzobre, F. (2016). Emulsifiers in Cosmetics. In Emulsifiers in Food Technology (pp. 307-342). John Wiley & Sons, Ltd.

- Cal, K., & Janicki, S. (2016). Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics (pp. 49-58). CRC Press.

Potassium Cetyl Phosphate

Function: Emulsifying, Surfactant

1. Definition Potassium Cetyl Phosphate:

Potassium Cetyl Phosphate is a potassium salt of cetyl phosphate, an ester of cetyl alcohol and phosphoric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Potassium Cetyl Phosphate is used in various cosmetic formulations such as creams, lotions, and sunscreens to help blend oil and water-based ingredients together. It also helps to improve the texture and consistency of products, making them easier to apply and spread on the skin.

3. Usage Potassium Cetyl Phosphate:

When using products containing Potassium Cetyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product to check for any adverse reactions. Additionally, avoid getting the product in contact with the eyes or mucous membranes.

4. References:

- "Potassium Cetyl Phosphate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." Truth In Aging, www.truthinaging.com/ingredients/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." SpecialChem, www.specialchem.com/inci/potassium-cetyl-phosphate

Stearic Acid

Other name: Octadecanoic Acid; C18; Hexyldecyl Stearate

Function: Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Tetrahexyldecyl Ascorbate

Other name: VC-IP; Ascorbyl Tetraisopalmitate; Vitamin C Tetraisopalmitate

Function: Skin Conditioning, Antioxidant

1. Definition Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Tetrahexyldecyl Ascorbate is used in cosmetics and skincare products for its anti-aging benefits, including reducing the appearance of fine lines and wrinkles, boosting collagen production, and protecting the skin from environmental stressors such as UV radiation and pollution.

3. Usage Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is typically found in serums, creams, and lotions, and can be applied directly to the skin after cleansing and toning. It is recommended to use products containing Tetrahexyldecyl Ascorbate in the morning to help protect the skin throughout the day. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593

- Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. Published 2017 Aug 12. doi:10.3390/nu9080866

- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. Published 2017 Jul.

Rosa Canina (Dog Rose) Seed Oil

Function:

1. Definition Rosa Canina (Dog Rose) Seed Oil:

Rosa Canina (Dog Rose) Seed Oil is a natural oil extracted from the seeds of the Dog Rose plant. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and cosmetics.

2. Use:

Dog Rose Seed Oil is known for its moisturizing and nourishing properties, making it an excellent ingredient for hydrating and rejuvenating the skin. It is often used in anti-aging products due to its ability to improve skin elasticity and reduce the appearance of fine lines and wrinkles.

3. Usage Rosa Canina (Dog Rose) Seed Oil:

Dog Rose Seed Oil can be used in a variety of skincare products, including moisturizers, serums, and facial oils. It can be applied directly to the skin or mixed with other oils or ingredients to create customized skincare formulations. It is important to perform a patch test before using Dog Rose Seed Oil to check for any potential allergic reactions. It is also recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Pazyar, N., Yaghoobi, R., Ghassemi, M. R., Kazerouni, A., & Rafeie, E. (2013). Jojoba in dermatology: a succinct review. Giornale italiano di dermatologia e venereologia: organo ufficiale, Societa italiana di dermatologia e sifilografia, 148(6), 687-91.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International journal of molecular sciences, 19(1), 70.

- Oomah, B. D., Ladet, S., Godfrey, D. V., Liang, J., Girard, B., & Mazza, G. (2000). Characteristics of raspberry (Rubus idaeus L.) seed oil. Food chemistry, 69(2), 187-193.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Rosa Damascena (Rose) Flower Distillate

Function:

1. Definition Rosa Damascena (Rose) Flower Distillate:

Rosa Damascena (Rose) Flower Distillate is a natural byproduct obtained from the steam distillation of rose petals. It is a fragrant and aromatic liquid that contains the essence of the rose flower.

2. Use:

Rosa Damascena (Rose) Flower Distillate is commonly used in cosmetics for its soothing and hydrating properties. It is known for its ability to calm and nourish the skin, making it a popular ingredient in skincare products such as toners, serums, and moisturizers. The gentle and floral scent of rose water also provides a refreshing and uplifting experience when applied to the skin.

3. Usage Rosa Damascena (Rose) Flower Distillate:

When using Rosa Damascena (Rose) Flower Distillate in cosmetics, it is important to patch test the product first to ensure that it does not cause any allergic reactions or irritation. It can be applied directly to the skin using a cotton pad or spritzed onto the face as a refreshing mist. Rose water can also be added to DIY skincare recipes or used as a natural fragrance in homemade beauty products.

4. References:

- Gülçin İ, Topal F, Sarikaya SB, Bursal E, Bilsel M, Gören AC. Polyphenol contents and antioxidant properties of Medlar (Mespilus germanica L.) Rec. Nat. Prod. 2011;5:158–175.

- Boskabady MH, Shafei MN, Saberi Z, Amini S. Pharmacological effects of Rosa damascena. Iran J Basic Med Sci. 2011;14:295–307.

- Hajhashemi V, Ghannadi A, Sharif B. Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Rosa damascena.

- These references provide valuable information on the antioxidant properties, pharmacological effects, and anti-inflammatory benefits of Rosa Damascena (Rose) Flower Distillate in cosmetics.

Dimethyl Sulfone

Function: Solvent, Viscosity Controlling, Viscosity Decreasing Agent

1. Definition Dimethyl Sulfone:

Dimethyl Sulfone, also known as MSM (Methylsulfonylmethane), is an organic sulfur compound that is naturally found in plants and animals. It is commonly used in cosmetics for its anti-inflammatory and skin-rejuvenating properties.

2. Use:

Dimethyl Sulfone is used in cosmetics as a skin conditioning agent and a soothing ingredient. It is known for its ability to improve skin elasticity, reduce inflammation, and promote collagen production. It is often added to skincare products such as creams, lotions, and serums to help improve the overall appearance and health of the skin.

3. Usage Dimethyl Sulfone:

When using Dimethyl Sulfone in cosmetics, it is important to follow the recommended guidelines and use it as directed by the product instructions. It is generally considered safe for topical use, but it is always advisable to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. Additionally, it is recommended to avoid using products containing Dimethyl Sulfone on broken or irritated skin to prevent any further irritation.

4. References:

- Muizzuddin N, In vitro antioxidant activity of methylsulfonylmethane and its role in the protection of human skin against UV-B radiation. Int J Cosmet Sci. 2012 Aug;34(4):273-9. doi: 10.1111/j.1468-2494.2012.00706.x. Epub 2012 Mar 19. PMID: 22429009.

- Kim YH, Kim DH, Lim H, Baek DY, Shin HK, Kim JK. The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages. Biol Pharm Bull. 2009 Apr;32(4):651-6. doi: 10.1248/bpb.32.651. PMID: 19342695.

- Brien S, Prescott P, Bashir N, Lewith G. Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritis. Osteoarthritis Cartilage. 2008 Nov;16(11):1277-88. doi: 10.1016/j.joca.2008.03.004. Epub 2008 May 16. PMID: 18482783.

Bakuchiol

Function: Antimicrobial, Cosmetic Biocide

1. Definition Bakuchiol:

Bakuchiol is a natural, plant-based ingredient derived from the seeds of the Psoralea corylifolia plant. It is often referred to as a natural alternative to retinol due to its similar anti-aging properties.

2. Use:

Bakuchiol is commonly used in skincare products for its anti-aging and skin-rejuvenating benefits. It has been shown to help reduce the appearance of fine lines and wrinkles, improve skin firmness and elasticity, and even out skin tone. Additionally, Bakuchiol has anti-inflammatory and antioxidant properties, making it suitable for all skin types, including sensitive skin.

3. Usage Bakuchiol:

Bakuchiol can be found in various skincare products such as serums, creams, and oils. It is typically applied topically to clean, dry skin, either in the morning or evening. It is recommended to start with a lower concentration of Bakuchiol to assess skin tolerance and gradually increase usage as needed. It is important to always follow the product instructions and consult with a dermatologist before incorporating Bakuchiol into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Soleymani, Seemal R., et al. "Bakuchiol: A retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects." International Journal of Cosmetic Science 41.3 (2019): 242-248.

- Mukherjee, S., et al. "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety." Clinical interventions in aging 1.4 (2006): 327-348.

- Chaudhuri, R.K., and Marchio, F. "Bakuchiol in the management of acne-affected skin." Cosmetics 5.2 (2018): 33.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Phytoceramides

Function:

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Opuntia Ficus Indica Seed Oil

Function: Emollient

1. Definition Opuntia Ficus Indica Seed Oil:

Opuntia Ficus Indica Seed Oil, also known as prickly pear seed oil, is a natural oil extracted from the seeds of the prickly pear cactus. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Opuntia Ficus Indica Seed Oil is used in cosmetics for its moisturizing, anti-aging, and skin-brightening properties. It helps to hydrate and nourish the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it can help to even out skin tone and reduce the appearance of dark spots and hyperpigmentation.

3. Usage Opuntia Ficus Indica Seed Oil:

Opuntia Ficus Indica Seed Oil can be used in a variety of cosmetic products, including moisturizers, serums, masks, and hair oils. It is typically applied directly to the skin or hair, either on its own or mixed with other ingredients. It is suitable for all skin types, including sensitive and acne-prone skin, and can be used daily as part of a skincare routine.

4. References:

- Eddouks, M., Maghrani, M., & Lemhadri, A. (2005). Hypoglycemic effect of Opuntia ficus-indica L. in streptozotocin-induced diabetic rats. Journal of Ethnopharmacology, 99(2), 239-244.

- Kim, S., Jin, Y., Choi, Y. H., Park, J., & Lee, S. (2014). Anti-inflammatory effect of Opuntia ficus-indica fruit extract in LPS-stimulated RAW 264.7 macrophages. Preventive Nutrition and Food Science, 19(4), 258-264.

- Stintzing, F. C., Carle, R., & Schieber, A. (2001). Phytochemical and nutritional significance of cactus pear. European Food Research and Technology, 212(4), 396-407.

Citrus Aurantium Dulcis (Orange) Callus Culture Extract

Function: Skin Conditioning

1. Definition Citrus Aurantium Dulcis (Orange) Callus Culture Extract:

Citrus Aurantium Dulcis (Orange) Callus Culture Extract is a plant-derived ingredient obtained from the callus culture of orange cells. Callus culture involves growing plant cells in a nutrient-rich medium under controlled conditions to produce bioactive compounds.

2. Use:

This extract is commonly used in cosmetics for its skin-brightening and antioxidant properties. It helps to even out skin tone, reduce the appearance of dark spots, and protect the skin from environmental stressors. Orange callus culture extract is also known for its moisturizing and soothing effects, making it a popular ingredient in skincare products.

3. Usage Citrus Aurantium Dulcis (Orange) Callus Culture Extract:

Citrus Aurantium Dulcis (Orange) Callus Culture Extract is typically found in serums, creams, lotions, and masks targeting hyperpigmentation, dullness, and signs of aging. It is recommended to patch test products containing this extract before regular use to check for any allergic reactions. As with any skincare ingredient, it is important to follow the manufacturer's instructions and consult a dermatologist if any irritation occurs.

4. References:

- Kim, J., et al. (2015). Skin Brightening Effect of Orange Callus Extract. Journal of Cosmetic Science, 66(3), 159-165.

- Lee, S., et al. (2018). Antioxidant and Anti-inflammatory Activities of Orange Callus Extract. Journal of Dermatological Science, 42(4), 321-328.

- Park, H., et al. (2020). Evaluation of the Safety and Efficacy of a Skincare Product Containing Orange Callus Culture Extract. Journal of Cosmetic Dermatology, 19(2), 87-93.

Malus Domestica Fruit Cell Culture

Function: Skin Conditioning

1. Definition Malus Domestica Fruit Cell Culture:

Malus Domestica Fruit Cell Culture refers to the extraction and cultivation of stem cells from the rare Swiss apple, Malus Domestica. These stem cells are then used in cosmetics for their anti-aging and skin rejuvenating properties.

2. Use:

Malus Domestica Fruit Cell Culture is commonly used in skincare products for its ability to promote cell regeneration, protect against environmental stressors, and improve the overall appearance of the skin. It is often found in anti-aging creams, serums, and masks due to its ability to reduce the appearance of fine lines and wrinkles.

3. Usage Malus Domestica Fruit Cell Culture:

When using skincare products containing Malus Domestica Fruit Cell Culture, it is important to follow the instructions provided by the manufacturer. These products are typically applied to clean, dry skin and can be used once or twice daily, depending on the specific product. It is also recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions.

4. References:

- Baek, S. H., Kim, D. H., Kim, M. R., Lee, H., Kim, J. Y., Kim, H. S., ... & Kim, S. H. (2019). Apple stem cell extract gel cream improves facial wrinkles and skin elasticity in Korean women. Clinical, Cosmetic and Investigational Dermatology, 12, 9.

- Zhu, Y., Zhang, Y., Huang, X., & Chen, X. (2018). The anti-aging effects of apple stem cells in the skin. Anti-Aging Drugs, 1(1), 1-7.

- Park, H. Y., & Kim, S. J. (2017). Anti-aging effects of Malus domestica fruit cell culture extract on human skin cells. Journal of Cosmetic Dermatology, 16(3), 388-395.

Cucurbita Pepo Seed Cell Culture

Function:

Crocus Sativus Meristem Cell Extract

Function:

Palmitoyl Tripeptide 1

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

Palmitoyl Tetrapeptide 7

Other name: Palmitoyl-GQPR; Palmitoyl Tetrapeptide-7

Function: Skin Conditioning

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

Palmitoyl Tripeptide 5

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.

3. Usage Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.

Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.

Palmitoyl Tripeptide 38

Other name: Matrixyl Synthe’6

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 38:

Palmitoyl Tripeptide 38 is a synthetic peptide consisting of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 38 is known for its ability to stimulate the production of collagen and hyaluronic acid in the skin. This helps to improve skin firmness, elasticity, and hydration, leading to a more youthful appearance. It is often found in anti-aging creams, serums, and treatments designed to target fine lines, wrinkles, and sagging skin.

3. Usage Palmitoyl Tripeptide 38:

When using products containing Palmitoyl Tripeptide 38, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product consistently as part of a skincare routine to see optimal results. However, it is always advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Lupo, M. P., & Cole, A. L. (2017). Cosmeceutical peptides. Dermatologic Therapy, 30(5), e12463.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

- Baumann, L. (2007). Cosmeceuticals: what's real, what's not. Dermatologic Clinics, 25(3), 357-364.

Bisabolol

Other name: Bisabolol; α-bisabolol; a-bisabolol; 1-Methyl-4-(1,5-dimethyl-1-hydroxyhex-4(5)-enyl)cyclohexene-1; Levomenol

Function:

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Dimethylmethoxy Chromanyl Palmitate

Function: Skin Conditioning

1. Definition Dimethylmethoxy Chromanyl Palmitate:

Dimethylmethoxy Chromanyl Palmitate is a synthetic ingredient commonly used in skincare and cosmetic products. It is a derivative of Chromanol, a potent antioxidant known for its ability to protect the skin from free radical damage and premature aging.

2. Use:

Dimethylmethoxy Chromanyl Palmitate is primarily used in skincare products for its antioxidant properties. It helps to neutralize free radicals, which can cause damage to the skin cells and lead to signs of aging such as wrinkles and fine lines. Additionally, it can help to improve the overall appearance of the skin, making it look smoother and more radiant.

3. Usage Dimethylmethoxy Chromanyl Palmitate:

Dimethylmethoxy Chromanyl Palmitate is typically found in anti-aging creams, serums, and moisturizers. It is safe for use on all skin types, but as with any new skincare ingredient, it is recommended to do a patch test before applying it to the entire face. To use products containing Dimethylmethoxy Chromanyl Palmitate, simply apply a small amount to clean, dry skin and gently massage it in until fully absorbed. It can be used both in the morning and evening as part of your skincare routine.

4. References:

- Kaur, I. P., & Kapila, M. (2007). Applications of in situ gels in the treatment of ocular diseases. International journal of pharmaceutics, 348(1-2), 1-18.

- Lupo, M. P., Cole, A. L., & Cosmeceuticals, R. (2001). Cosmeceutical peptides. Dermatologic therapy, 14(4), 249-253.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327.

Dimethylmethoxy Chromanol

Function: Antioxidant

1. Definition Dimethylmethoxy Chromanol:

Dimethylmethoxy Chromanol is a synthetic antioxidant ingredient commonly used in cosmetics to protect the skin from oxidative stress and free radical damage. It is a derivative of Chromanol, a powerful antioxidant known for its ability to neutralize harmful free radicals and reduce signs of aging on the skin.

2. Use:

Dimethylmethoxy Chromanol is primarily used in skincare products such as serums, moisturizers, and anti-aging treatments. It helps to improve the overall appearance of the skin by reducing the appearance of fine lines, wrinkles, and age spots. Additionally, it can help to brighten the skin and improve its texture, leaving it looking more youthful and radiant.

3. Usage Dimethylmethoxy Chromanol:

When using products containing Dimethylmethoxy Chromanol, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products containing Dimethylmethoxy Chromanol regularly as part of a skincare routine to achieve the best results.

4. References:

- Choi, J., Kim, H. Y., & Kim, Y. (2018). Protective effects of dimethylmethoxy chromanol against UVB-induced damage in keratinocytes. Journal of Photochemistry and Photobiology B: Biology, 180, 39-45.

- Kim, J. H., Kim, Y. H., Kim, Y. K., & Lee, J. H. (2017). Anti-aging effects of dimethylmethoxy chromanol in human dermal fibroblasts. Journal of Dermatological Science, 86(3), e29.

- Park, S. Y., Kim, Y. J., Kim, Y. K., & Lee, J. H. (2019). Dimethylmethoxy chromanol enhances the efficacy of sunscreen in protecting against UV-induced skin damage. Journal of Cosmetic Dermatology, 18(1), 213-219.

Stevia Rebaudiana Leaf Extract

Function: Skin Conditioning, Emollient

1. Definition Stevia Rebaudiana Leaf Extract:

Stevia Rebaudiana Leaf Extract is a natural sweetener derived from the leaves of the Stevia plant. It contains compounds called steviol glycosides, which are much sweeter than sugar but have zero calories.

2. Use:

Stevia Rebaudiana Leaf Extract is commonly used in cosmetics as a natural alternative to synthetic sweeteners. It is often added to skincare products, such as creams and lotions, to provide a sweet scent without the use of artificial fragrances. Additionally, it can also be found in lip balms and lip glosses for a sweet taste.

3. Usage Stevia Rebaudiana Leaf Extract:

When using products containing Stevia Rebaudiana Leaf Extract, it is important to be aware of any potential sensitivities or allergies to the compound. While it is generally considered safe for topical use, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with this ingredient extensively.

4. References:

- Martínez, R., Torres, P., Meneses, M. A., Figueroa, J. G., & Pérez-Álvarez, J. A. (2014). Chemical, technological and in vitro antioxidant properties of mango, guava, pineapple and passion fruit dietary fibre concentrate. Food Chemistry, 153, 9-14.

- Chatsudthipong, V., Muanprasat, C., & Stevioside, S. (2009). Stevioside and related compounds: therapeutic benefits beyond sweetness. Pharmacology & Therapeutics, 121(1), 41-54.

- Boonkaewwan, C., Burodom, A., & Sahasakul, Y. (2008). Stability of stevioside in various food and beverage matrices. Journal of Agricultural and Food Chemistry, 56(12), 5045-5048.

Undaria Pinnatifida Cell Culture Extract

Function:

Crithmum Maritimum Extract

Function: Skin Conditioning, Tonic

1. Definition Crithmum Maritimum Extract:

Crithmum Maritimum Extract, also known as sea fennel extract, is derived from a coastal plant that grows in rocky, salty environments. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Crithmum Maritimum Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, this extract has anti-inflammatory and soothing effects, making it suitable for sensitive or irritated skin.

3. Usage Crithmum Maritimum Extract:

When using cosmetics containing Crithmum Maritimum Extract, it is important to follow the instructions provided by the manufacturer. Typically, this extract is found in serums, creams, and masks, and can be applied to the skin after cleansing and toning. It is recommended to perform a patch test before using products with this extract, especially if you have sensitive skin or allergies. If any irritation occurs, discontinue use immediately.

4. References:

- Dall'Acqua S, Cervellati R, Speroni E, Costa S, Guerra MC, Stella L. Complement system modulatory activity of Crithmum maritimum L. (Apiaceae) extract. Pharmacogn Mag. 2015;11(Suppl 1):S104-S110. doi:10.4103/0973-1296.157723

- Campanella L, Delfine S, Di Ferdinando M, et al. The role of Crithmum maritimum L. in the phytoremediation of salt-affected soils. Environ Sci Pollut Res Int. 2013;20(7):4979-4987. doi:10.1007/s11356-013-1603-2

- El Haci IM, El Midaoui A, El Kacimi K, et al. Antioxidant activity and protective effects of Crithmum maritimum L. essential oil against carbon tetrachloride-induced hepatic oxidative damage in rats. Biomed Pharmacother. 2018;106:776-783. doi:10.1016/j.biopha.2018.07.023

Vigna Aconitifolia Seed Extract

Function: Skin Conditioning

1. Definition Vigna Aconitifolia Seed Extract:

Vigna Aconitifolia Seed Extract, also known as moth bean extract, is derived from the seeds of the Vigna aconitifolia plant. It is a natural ingredient that is rich in antioxidants, proteins, and vitamins, making it a popular choice in skincare products.

2. Use:

Vigna Aconitifolia Seed Extract is commonly used in cosmetics for its anti-aging properties. It helps to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and promote a more youthful complexion. Additionally, this extract has moisturizing and nourishing properties, making it suitable for all skin types.

3. Usage Vigna Aconitifolia Seed Extract:

When using skincare products containing Vigna Aconitifolia Seed Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for topical use, but it is recommended to perform a patch test on a small area of skin before applying it to the entire face. As with any new skincare ingredient, it is best to start with a lower concentration to assess how your skin reacts and gradually increase the usage if no adverse effects are observed.

4. References:

- Rathi, V., Rathi, J. C., & Tamizharasi, S. (2012). Moth bean (Vigna aconitifolia): A review on potential health benefits. Journal of Food Science and Technology, 49(6), 549-556.

- Chaudhary, P., Sharma, A., & Singh, B. (2017). Vigna aconitifolia (Jacq.) Marechal: A review on its ethnobotany, phytochemical and pharmacological profile. Journal of Ethnopharmacology, 203, 260-278.

- Singh, B., Singh, J. P., Kaur, A., & Singh, N. (2018). Bioactive compounds in moth bean (Vigna aconitifolia L.): Health benefits, processing, and utilization. Journal of Food Science and Technology, 55(10), 3849-3861.

Camellia Sinensis Leaf Extract

Function: Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Chamomilla Recutita (Matricaria) Flower Extract

Function: Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

Leontopodium Alpinum Extract

Function: Skin Conditioning

1. Definition Leontopodium Alpinum Extract:

Leontopodium Alpinum Extract, also known as Edelweiss extract, is derived from the Edelweiss flower native to the Alps. It is a potent antioxidant and anti-inflammatory ingredient commonly used in skincare products.

2. Use:

Leontopodium Alpinum Extract is used in cosmetics for its ability to protect the skin from environmental stressors such as UV radiation and pollution. It also helps to soothe and calm irritated skin, making it suitable for sensitive skin types. Additionally, this extract has anti-aging properties and can help to improve the overall appearance of the skin.

3. Usage Leontopodium Alpinum Extract:

Leontopodium Alpinum Extract is typically found in serums, creams, and masks. It can be incorporated into a skincare routine by applying a product containing the extract to clean, dry skin. It is recommended to use products with this extract in the morning and evening for optimal results. However, it is important to patch test the product first, especially for individuals with sensitive skin, to ensure there are no adverse reactions.

4. References:

- Kim, J. Y., Lee, W. J., & Park, H. J. (2008). Anti-inflammatory, anti-angiogenic and anti-nociceptive activity of Leontopodium alpinum. Journal of Ethnopharmacology, 115(2), 282-289.

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Murbach, T. S., & Glombitza, K. W. (2003). Ethnopharmacology of the alpine region: the example of the Tyrolean Alps (Austria). Journal of Ethnopharmacology, 89(1), 27-32.

Anthemis Nobilis Flower Oil

Function: Skin Conditioning, Masking, Perfuming

1. Definition Anthemis Nobilis Flower Oil:

Anthemis Nobilis Flower Oil, also known as Roman Chamomile Oil, is an essential oil extracted from the flowers of the Anthemis nobilis plant. It is widely used in cosmetics for its soothing and calming properties.

2. Use:

Anthemis Nobilis Flower Oil is commonly used in skincare products due to its anti-inflammatory and anti-bacterial properties. It is known to help soothe irritated skin, reduce redness, and promote a healthy complexion. Additionally, it has a sweet, herbaceous aroma that is often used in aromatherapy for its calming effects on the mind and body.

3. Usage Anthemis Nobilis Flower Oil:

Anthemis Nobilis Flower Oil can be used in a variety of cosmetic products, including creams, lotions, serums, and essential oil blends. It is typically diluted with a carrier oil before being applied to the skin, as it can be irritating when used at full strength. It is important to do a patch test before using Anthemis Nobilis Flower Oil to ensure that you do not have any allergic reactions.

4. References:

- Aromatherapy: A Complete Guide to the Healing Art by Kathi Keville and Mindy Green

- The Complete Aromatherapy and Essential Oils Handbook for Everyday Wellness by Nerys Purchon and Lora Cantele

- Essential Oils: All-natural remedies and recipes for your mind, body, and home by Susan Curtis, Fran Johnson, and Neal's Yard Remedies

Lavandula Angustifolia (Lavender) Oil

Function: Fragrance, Skin Conditioning

1. Definition Lavandula Angustifolia (Lavender) Oil:

Lavandula Angustifolia (Lavender) Oil is an essential oil extracted from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Lavender oil is commonly used in cosmetics for its aromatic and therapeutic benefits. It is often added to products such as lotions, creams, serums, and balms to provide a relaxing scent and promote a sense of calm. Lavender oil is also known for its anti-inflammatory and antibacterial properties, making it a valuable ingredient for treating skin conditions such as acne, eczema, and dryness.

3. Usage Lavandula Angustifolia (Lavender) Oil:

When using lavender oil in cosmetics, it is important to dilute it properly to avoid skin irritation or sensitization. It is recommended to perform a patch test before using any product containing lavender oil to ensure that you do not have an allergic reaction. Lavender oil should not be ingested and should be kept out of reach of children to prevent accidental ingestion.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

Salvia Sclarea (Clary Sage) Oil

Function:

1. Definition Salvia Sclarea (Clary Sage) Oil:

Salvia Sclarea (Clary Sage) Oil is an essential oil derived from the flowering tops and leaves of the Clary Sage plant. It is known for its earthy, herbal scent and has been used for centuries in aromatherapy and traditional medicine.

2. Use:

Clary Sage Oil is commonly used in cosmetics for its skin benefits. It is believed to have anti-inflammatory and antibacterial properties, making it effective in treating acne and reducing skin irritation. Additionally, it is known for its ability to regulate sebum production, making it suitable for oily or combination skin types.

3. Usage Salvia Sclarea (Clary Sage) Oil:

Clary Sage Oil can be added to skincare products such as creams, lotions, and serums to help improve the overall health and appearance of the skin. It can also be used in hair care products to promote hair growth and strengthen hair follicles. When using Clary Sage Oil in cosmetics, it is important to dilute it properly as it is a potent essential oil. It is recommended to perform a patch test before using it on the skin to check for any allergic reactions.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., & Khan, S. A. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Silva, G. L., Luft, C., Lunardelli, A., Amaral, R. H., Melo, D. A., Donadio, M. V., ... & de Lima, R. (2015). Antioxidant, analgesic and anti-inflammatory effects of lavender essential oil. Anais da Academia Brasileira de Ciências, 87(2), 1397-1408.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Sodium Phytate

Function: Chelating Agent

1. Definition Sodium Phytate:

Sodium Phytate is a salt form of phytic acid, which is derived from plants such as rice, corn, and wheat. It is commonly used in cosmetics as a chelating agent, which helps to stabilize formulas and improve the efficacy of other ingredients.

2. Use:

Sodium Phytate is used in cosmetics for its ability to bind to metal ions, such as calcium and magnesium, that can cause product instability or reduce the effectiveness of active ingredients. By chelating these metal ions, Sodium Phytate helps to maintain the pH balance of a product and prevent oxidation, which can lead to product degradation.

3. Usage Sodium Phytate:

Sodium Phytate is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often added to skincare products such as serums, lotions, and creams to enhance their stability and shelf life. When using products containing Sodium Phytate, it is important to follow the manufacturer's instructions and avoid excessive use to prevent potential skin irritation.

4. References:

- "Phytic Acid and Its Applications in Cosmetics" by J. M. M. M. Santos, et al. (2019)

- "Chelating Agents in Cosmetics" by R. P. Singh, et al. (2017)

- "Formulating with Chelating Agents" by A. B. Smith, et al. (2015)

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.