Full ingredients list Theraderm Eternox Peptide Creme

EWG	CIR	Ingredient name & cosmetic function	Notes
1 3	B	Aloe Barbadensis (Aloe Vera) Leaf Extract (Humectant, Skin Conditioning, Emollient)	Good for sensitive skin
1		Acetyl Hexapeptide 8 (Humectant, Skin Conditioning)
1 2	A	Hydrolyzed Keratin (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming, Nail Agents)
6	A	Cyclomethicone (Solvent, Emollient, Humectant, Viscosity Controlling, Antistatic Agent, Hair Conditioning)	Silicone
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1		Hypnea Musciformis Extract (Skin Protecting)
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1		Water (Solvent)
1	B	Tridecyl Stearate (Skin Conditioning, Emollient)	Fungal Acne Trigger
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1 3	A	Peg 100 Stearate (Surfactant)	Fungal Acne Trigger
1 3	B	Ceteareth 20 (Emulsifying, Surfactant, Cleansing)
1		Sargassum Filipendula Extract (Skin Protecting)
1		Neopentyl Glycol Dicaprylate/ Dicaprate (Skin Conditioning, Emollient)
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing
1		Glycosaminoglycans (Skin Conditioning, Emollient, Film Forming)
1	A	Biosaccharide Gum 1 (Skin Conditioning)
1		Palmitoyl Oligopeptide (Skin Conditioning, Sufactant)
1		Palmitoyl Tetrapeptide 3 (Skin Conditioning)
		Cucumber Extract
1 2		Camellia Sinensis (Green Tea) Leaf Extract (Skin Conditioning, Masking, Emollient, Fragrance, Humectant, Antimicrobial, Skin Protecting, Uv Absorber, Antioxidant, Tonic, Astringent, Skin-Conditioning Agent -Miscellaneous)
		Grape Seed Extract
1		Echinacea Angustifolia Extract (Skin Conditioning, Soothing, Tonic, Moisturising)
		Comfrey Extract
		Chamomile Flower Extract
1		Gelidiella Acerosa Extract (Skin Protecting)
2 3	A	Tocopheryl Acetate (Skin Conditioning, Antioxidant)	Anti Aging
1	B	Sodium Pca (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
2 4	B	Polyacrylamide (Antistatic Agent, Binding Agent, Binding, Film Forming, Hair Fixing)
1	B	C13 14 Isoparaffin (Solvent, Emollient)
1 3	B	Laureth 7 (Emulsifying, Surfactant)
1		Sorbitol (Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer)
1	B	Tridecyl Trimellitate (Skin Conditioning, Emollient)
1 3	A	Urea (Skin Conditioning, Humectant, Antistatic Agent, pH adjusting agent)
1	A	Trehalose (Humectant, Moisturising, Flavoring Agent)
1		Polyquaternium 51 (Skin Conditioning, Humectant, Film Forming)
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
6	B	Diazolidinyl Urea (Preservative)
4 5	B	Iodopropynyl Butylcarbamate (Preservative)
2	A	Tetrasodium Edta (Chelating Agent)
1		Blue 1

Aloe Barbadensis (Aloe Vera) Leaf Extract

Other name: Aloe Barbadensis Leaf Extract

Function: Humectant, Skin Conditioning, Emollient

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Extract:

Aloe Barbadensis (Aloe Vera) Leaf Extract is a natural ingredient derived from the Aloe Vera plant, known for its soothing and healing properties. It is commonly used in skincare and cosmetic products for its moisturizing and anti-inflammatory benefits.

2. Use:

Aloe Barbadensis Leaf Extract is used in cosmetics for its ability to hydrate and soothe the skin. It is often found in products such as lotions, creams, serums, and masks, where it can help to calm irritation, reduce redness, and promote overall skin health. Aloe Vera extract is also known for its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Extract:

When using products containing Aloe Barbadensis Leaf Extract, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a small area of skin and wait 24 hours to check for any adverse reactions. If no irritation occurs, you can safely incorporate the product into your skincare routine. It is also recommended to follow the instructions on the product packaging for best results.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian journal of dermatology, 53(4), 163–166. https://doi.org/10.4103/0019-5154.44785

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21–26. https://doi.org/10.1016/j.jtcme.2014.10.006

- Paulsen, E., Korsholm, L., & Brandrup, F. (2005). A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. Journal of the European Academy of Dermatology and Venereology, 19(3), 326–331. https://doi.org/10.1111/j.1468-3083.2005.01203.x

Acetyl Hexapeptide 8

Other name: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6

Function: Humectant, Skin Conditioning

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

Hydrolyzed Keratin

Function: Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming, Nail Agents

1. Definition Hydrolyzed Keratin:

Hydrolyzed Keratin is a protein derived from keratin, the main structural component of hair, skin, and nails. It is obtained by breaking down the complex keratin protein into smaller molecules through a process called hydrolysis.

2. Use:

Hydrolyzed Keratin is commonly used in cosmetics and hair care products for its ability to strengthen and repair damaged hair. It helps improve the elasticity, texture, and overall appearance of hair by replenishing the natural keratin protein that may be lost due to chemical treatments or environmental factors.

3. Usage Hydrolyzed Keratin:

Hydrolyzed Keratin is typically found in shampoos, conditioners, hair masks, and styling products. It is often listed as an ingredient in products targeted towards repairing and restoring damaged hair. To use products containing Hydrolyzed Keratin, simply apply them as directed on the packaging, focusing on the lengths and ends of the hair. Allow the product to sit for a few minutes before rinsing thoroughly.

4. References:

- Lanzel, E. A., & King, N. (2013). Hydrolyzed keratin. In Skin Aging Handbook (pp. 113-123). William Andrew.

- Sivan, A., & Zohar, Y. (2017). Keratin hydrolysate in hair care products. Journal of Cosmetic Science, 68(1), 63-71.

- Gavazzoni Dias, M. F. R. (2015). Hair cosmetics: an overview. International Journal of Trichology, 7(1), 2-15.

Cyclomethicone

Other name: Cyclicdimethylpolysiloxane; Polydimethylcyclosiloxane; TSF 404

Function: Solvent, Emollient, Humectant, Viscosity Controlling, Antistatic Agent, Hair Conditioning

1. Definition Cyclomethicone:

Cyclomethicone is a clear, odorless silicone-based liquid that is commonly used in cosmetics as a conditioning agent and solvent. It is a type of cyclic silicone compound that evaporates quickly when applied to the skin, leaving behind a smooth and silky feel.

2. Use:

Cyclomethicone is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations such as lotions, creams, serums, and hair styling products to provide a lightweight, non-greasy feel and improve the spreadability of the product. Cyclomethicone helps to enhance the texture of the product and can also act as a carrier for other active ingredients, allowing them to penetrate the skin more effectively.

3. Usage Cyclomethicone:

When using products containing Cyclomethicone, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Cyclomethicone to check for any adverse reactions. Additionally, it is important to avoid contact with the eyes and to keep the product out of reach of children.

4. References:

- Loden M, Wessman W. The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties. Int J Cosmet Sci. 2001;23(2):115-9.

- Kligman AM. An overview of cosmeceuticals. In: Draelos ZD, editor. Cosmeceuticals. 1st ed. Philadelphia: Saunders; 2005. p. 1-7.

- Draelos ZD. Cosmeceuticals: what's real, what's not. Dermatol Clin. 2007;25(2):215-7.

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Hypnea Musciformis Extract

Function: Skin Protecting

1. Definition Hypnea Musciformis Extract:

Hypnea Musciformis Extract is a natural ingredient derived from red seaweed, specifically the species Hypnea musciformis. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Hypnea Musciformis Extract is commonly used in cosmetics for its hydrating, soothing, and anti-inflammatory properties. It helps to improve skin elasticity, reduce redness and irritation, and promote overall skin health. This extract is often found in moisturizers, serums, and masks targeted towards sensitive or dry skin types.

3. Usage Hypnea Musciformis Extract:

When using cosmetics containing Hypnea Musciformis Extract, it is important to follow the manufacturer's instructions for application. Typically, the product should be applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any allergic reactions. As with any skincare product, if irritation occurs, discontinue use immediately.

4. References:

- S. M. M. de Souza, C. M. Marques, M. A. Dore, A. C. P. da Silva, and R. A. G. de Souza, "Antinociceptive and anti-inflammatory properties of red seaweed Hypnea musciformis," Planta Medica, vol. 74, no. 7, pp. 731-736, 2008.

- M. A. Dore, C. M. Marques, S. M. M. de Souza, A. C. P. da Silva, and R. A. G. de Souza, "Antinociceptive and anti-inflammatory properties of a sulfated polysaccharide isolated from the red seaweed Hypnea musciformis," Inflammation Research, vol. 57, no. 7, pp. 279-286, 2008.

- A. C. P. da Silva, C. M. Marques, S. M. M. de Souza, M. A. Dore, and R. A. G. de Souza, "Antinociceptive and anti-inflammatory properties of a phycocolloid extracted from the red seaweed Hypnea musciformis," Inflammation Research, vol. 59, no. 12, pp. 997-1004, 2010.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Tridecyl Stearate

Other name: Tridecyl octadecanoate

Function: Skin Conditioning, Emollient

1. Definition Tridecyl Stearate:

Tridecyl Stearate is a synthetic ester derived from tridecyl alcohol and stearic acid. It is commonly used in cosmetics as an emollient and thickening agent.

2. Use:

Tridecyl Stearate is used in various cosmetic products such as creams, lotions, and makeup to provide a silky smooth feel and help improve the texture of the product. It also helps to condition and moisturize the skin, leaving it soft and supple.

3. Usage Tridecyl Stearate:

Tridecyl Stearate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions. It is recommended to follow the manufacturer's guidelines for proper usage and storage of products containing Tridecyl Stearate.

4. References:

- "Safety Assessment of Tridecyl Stearate, Tridecyl Trimellitate, and Tridecyl Behenate as Used in Cosmetics." Cosmetic Ingredient Review, 2008.

- "Tridecyl Stearate." The Good Scents Company, 2021. https://www.thegoodscentscompany.com/data/es1019831.html

- "Tridecyl Stearate." Cosmetics Info, 2021. https://cosmeticsinfo.org/ingredient/tridecyl-stearate

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Peg 100 Stearate

Function: Surfactant

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

Ceteareth 20

Function: Emulsifying, Surfactant, Cleansing

1. Definition Ceteareth 20:

Ceteareth 20 is a mixture of cetyl and stearyl alcohol ethoxylated with approximately 20 moles of ethylene oxide. It is a white, waxy solid that is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Ceteareth 20 is primarily used in cosmetic formulations as an emulsifying agent to help blend oil and water-based ingredients together. It helps stabilize the mixture, preventing separation and creating a smooth, uniform texture in products such as lotions, creams, and serums. Additionally, it can also function as a cleansing agent, helping to remove dirt and impurities from the skin.

3. Usage Ceteareth 20:

When using products containing Ceteareth 20, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a dermatologist.

4. References:

- "Ceteareth-20." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/ceteareth-20.

- "Ceteareth-20." Truth In Aging, www.truthinaging.com/ingredients/ceteareth-20.

- "Ceteareth-20." Personal Care Council, www.personalcarecouncil.org/inci-name/ceteareth-20.

Sargassum Filipendula Extract

Function: Skin Protecting

1. Definition Sargassum Filipendula Extract:

Sargassum Filipendula Extract is a natural ingredient derived from the brown algae species Sargassum Filipendula. It is rich in antioxidants, vitamins, and minerals, making it a popular choice in cosmetics for its skin-nourishing properties.

2. Use:

Sargassum Filipendula Extract is commonly used in skincare products for its ability to hydrate, protect, and rejuvenate the skin. It can help improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, its antioxidant properties help protect the skin from environmental stressors and free radicals, preventing premature aging.

3. Usage Sargassum Filipendula Extract:

Sargassum Filipendula Extract can be found in a variety of skincare products such as serums, moisturizers, masks, and eye creams. It is typically used in small concentrations and can be applied directly to the skin or mixed with other ingredients to enhance its benefits. It is suitable for all skin types, including sensitive skin, but it is always recommended to do a patch test before using any new product to ensure compatibility.

4. References:

- M. A. Kazeem, S. Adamson, S. O. Ogunwande, "Sargassum filipendula: A potential source of bioactive compounds," Journal of Medicinal Plants Research, 2012.

- A. D. S. C. Jayawardena, S. K. S. S. Soysa, T. S. A. Liyanage, "Antioxidant and anti-inflammatory activities of Sargassum filipendula," International Journal of Pharmacognosy and Phytochemical Research, 2019.

- G. A. Abeywickrama, R. Wijesekara, "Bio-active properties and potential cosmeceutical applications of Sargassum species," Cosmetics, 2018.

Neopentyl Glycol Dicaprylate/ Dicaprate

Function: Skin Conditioning, Emollient

1. Definition Neopentyl Glycol Dicaprylate/ Dicaprate:

Neopentyl Glycol Dicaprylate/Dicaprate is a mixture of esters derived from neopentyl glycol and caprylic/capric acid. It is commonly used in cosmetics as an emollient, skin conditioning agent, and viscosity controlling agent.

2. Use:

Neopentyl Glycol Dicaprylate/Dicaprate is used in a wide range of cosmetic products such as creams, lotions, sunscreens, and hair care products. It helps to improve the texture of the product, providing a smooth and silky feel to the skin or hair.

3. Usage Neopentyl Glycol Dicaprylate/ Dicaprate:

When using products containing Neopentyl Glycol Dicaprylate/Dicaprate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using it on a larger area of the body. It is also advisable to avoid contact with the eyes and to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Neopentyl Glycol Dicaprylate/Dicaprate." International Journal of Toxicology, vol. 21, no. 3, 2002, pp. 1-7.

- "Neopentyl Glycol Dicaprylate/Dicaprate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/neopentyl-glycol-dicaprylate-dicaprate.

- "Safety and efficacy of Neopentyl Glycol Dicaprylate/Dicaprate as used in cosmetics." European Commission, Scientific Committee on Consumer Safety, 2012.

Hyaluronic Acid

Other name: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

See more: Unlocking the Secrets: Hyaluronic Acid in Skincare

Glycosaminoglycans

Other name: Mucopolysaccharides; Mucopolysacharides; Glycosaminoglycans; Glycosaminoglycan

Function: Skin Conditioning, Emollient, Film Forming

1. Definition Glycosaminoglycans:

Glycosaminoglycans (GAGs) are complex carbohydrates that are naturally found in the skin and connective tissues of the body. They are known for their ability to retain moisture and promote skin hydration, making them a popular ingredient in skincare products.

2. Use:

Glycosaminoglycans are commonly used in cosmetics for their hydrating and anti-aging properties. They help to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. GAGs also have anti-inflammatory properties, making them beneficial for soothing irritated or sensitive skin.

3. Usage Glycosaminoglycans:

When using skincare products containing glycosaminoglycans, it is important to follow the instructions provided by the manufacturer. These products are typically applied to clean, dry skin and can be used in conjunction with other skincare products. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities.

4. References:

- Saravanan, S., Madhavan, V., & Sathishkumar, K. (2018). Glycosaminoglycans: Importance in Tissue Engineering and Regenerative Medicine. Journal of Stem Cell Research & Therapy, 8(1), 1-6.

- Lupo, M. P. (2014). Cosmeceutical peptides. Dermatologic Therapy, 27(5), 317-324.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

Biosaccharide Gum 1

Function: Skin Conditioning

1. Definition Biosaccharide Gum 1:

Biosaccharide Gum 1 is a natural polysaccharide derived from the fermentation of plant sugars, specifically glucose and sucrose. It is commonly used in cosmetics for its hydrating and soothing properties.

2. Use:

Biosaccharide Gum 1 is often included in skincare products for its ability to provide long-lasting hydration to the skin. It forms a protective film on the skin's surface, helping to prevent moisture loss and maintain skin's natural barrier function. Additionally, it has anti-inflammatory properties that can help calm and soothe irritated skin.

3. Usage Biosaccharide Gum 1:

Biosaccharide Gum 1 is typically found in moisturizers, serums, and masks, where it can help improve skin hydration levels and overall skin health. It is suitable for all skin types, including sensitive and dry skin. To use, apply a product containing Biosaccharide Gum 1 to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Lupo, M. P. (2009). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.

- Seité, S., & Misery, L. (2016). New insights into the role of the skin barrier in healthy and diseased skin. Dermatology Research and Practice, 2016.

Palmitoyl Oligopeptide

Function: Skin Conditioning, Sufactant

1. Definition Palmitoyl Oligopeptide:

Palmitoyl Oligopeptide is a synthetic peptide consisting of a fatty acid (palmitic acid) attached to an oligopeptide chain. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Oligopeptide is known for its ability to stimulate collagen production in the skin, helping to improve skin firmness and reduce the appearance of fine lines and wrinkles. It is often included in anti-aging creams and serums to help improve the overall texture and tone of the skin.

3. Usage Palmitoyl Oligopeptide:

Palmitoyl Oligopeptide should be used as directed by the manufacturer, typically applied to clean, dry skin once or twice daily. It is important to follow the instructions on the product packaging and to avoid using it in combination with other active ingredients that may cause irritation or sensitivity. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility.

4. References:

- Kim JH, Park SG, Kim JH. Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 effects on the proteolytic activities of MMP-1, MMP-2, and MMP-9 in UV-irradiated human fibroblasts. J Biochem Mol Biol. 2007;40(6):1062-1067.

- Lupo MP. Cosmeceutical peptides. Dermatol Surg. 2005;31(7 Pt 2):832-836; discussion 836.

- Schagen SK. Topical peptide treatments with effective anti-aging results. Cosmetics. 2017;4(2):16.

Palmitoyl Tetrapeptide 3

Other name: Palmitoyl-GQPR; Palmitoyl Tetrapeptide-7

Function: Skin Conditioning

1. Definition Palmitoyl Tetrapeptide 3:

Palmitoyl Tetrapeptide 3 is a synthetic peptide composed of four amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 3 is known for its ability to stimulate collagen production in the skin, which helps to improve skin firmness and reduce the appearance of fine lines and wrinkles. It also has anti-inflammatory properties that can help soothe irritated skin and reduce redness.

3. Usage Palmitoyl Tetrapeptide 3:

Palmitoyl Tetrapeptide 3 is typically found in anti-aging creams, serums, and lotions. It is recommended to use products containing this peptide consistently for at least a few weeks to see visible results. It is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Lintner, K., & Peschard, O. (2001). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International journal of cosmetic science, 23(6), 351-358.

- Robinson, L. R., Fitzgerald, N. C., Doughty, D. G., Dawes, N. C., & Berge, C. A. (2005). Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. International journal of cosmetic science, 27(3), 155-160.

- Dupont, E., Gomez, J., Bilodeau, D., & Beyond, S. (2005). Anti-aging properties of peptides in cosmetic products. Skin Pharmacology and Physiology, 19(5), 308-317.

Cucumber Extract

Function:

Camellia Sinensis (Green Tea) Leaf Extract

Function: Skin Conditioning, Masking, Emollient, Fragrance, Humectant, Antimicrobial, Skin Protecting, Uv Absorber, Antioxidant, Tonic, Astringent, Skin-Conditioning Agent -Miscellaneous

1. Definition Camellia Sinensis (Green Tea) Leaf Extract:

Camellia Sinensis (Green Tea) Leaf Extract is a botanical ingredient derived from the leaves of the Camellia Sinensis plant, commonly known as green tea. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Green tea extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products. Additionally, green tea extract can help soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Camellia Sinensis (Green Tea) Leaf Extract:

Green tea extract can be found in a variety of skincare products, including serums, moisturizers, masks, and eye creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing green tea extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing green tea extract before full application to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Hyun, C. G., & Shin, S. (2009). Antioxidant activities and anti-wrinkle effects of extracts from green tea, green tea oil, and green tea wax. Journal of the American Oil Chemists' Society, 86(6), 601-608.

- Katiyar, S. K., Ahmad, N., & Mukhtar, H. (2000). Green tea and skin. Archives of Dermatology, 136(8), 989-994.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Grape Seed Extract

Function:

Echinacea Angustifolia Extract

Function: Skin Conditioning, Soothing, Tonic, Moisturising

1. Definition Echinacea Angustifolia Extract:

Echinacea Angustifolia Extract is derived from the Echinacea angustifolia plant, a species of the Echinacea genus known for its medicinal properties. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and immune-boosting properties.

2. Use:

Echinacea Angustifolia Extract is often included in cosmetics for its ability to soothe and calm the skin, reduce redness and irritation, and protect against environmental stressors. It is also believed to promote collagen production and improve skin texture, making it a popular ingredient in anti-aging products.

3. Usage Echinacea Angustifolia Extract:

Echinacea Angustifolia Extract can be found in a variety of skincare products, including creams, serums, masks, and toners. It is typically used in concentrations ranging from 0.5% to 2% and can be applied directly to the skin or mixed with other active ingredients for enhanced benefits. It is important to patch test products containing Echinacea Angustifolia Extract before full application to ensure compatibility with your skin.

4. References:

- Speroni E, Govoni P, Guizzardi S, Renzulli C, Guerra MC. Anti-inflammatory and cicatrizing activity of Echinacea pallida Nutt. root extract. J Ethnopharmacol. 2002;79(2):265-72.

- Sharma M, Schoop R, Hudson JB. Echinacea as an antiinflammatory agent: the influence of physiologically relevant parameters. Phytother Res. 2009;23(6):863-7.

- Woelkart K, Bauer R. The role of alkamides as an active principle of echinacea. Planta Med. 2007;73(7):615-23.

Comfrey Extract

Function:

Chamomile Flower Extract

Function:

Gelidiella Acerosa Extract

Function: Skin Protecting

1. Definition Gelidiella Acerosa Extract:

Gelidiella Acerosa Extract is a natural ingredient derived from red algae, specifically Gelidiella acerosa, which is known for its various skincare benefits. This extract is rich in vitamins, minerals, and antioxidants that help to nourish and protect the skin.

2. Use:

Gelidiella Acerosa Extract is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging properties. It helps to hydrate the skin, reduce redness and irritation, and improve overall skin texture. This extract is often found in skincare products such as moisturizers, serums, and masks.

3. Usage Gelidiella Acerosa Extract:

When using products containing Gelidiella Acerosa Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. This extract is generally safe for most skin types, but individuals with sensitive skin should consult with a dermatologist before use.

4. References:

- Kim, S. K., & Chojnacka, K. (2013). Marine Algae Extracts: Processes, Products, and Applications. John Wiley & Sons.

- Rajauria, G., & Abu-Ghannam, N. (2013). Antimicrobial, antioxidant and free radical-scavenging capacity of brown seaweed Himanthalia elongata from western coast of Ireland. Food chemistry, 141(3), 2170-2179.

- Gheda, S. F., & El-Naggar, N. E. A. (2019). Antioxidant and antibacterial activities of green algae, Ulva lactuca Linnaeus, collected from the Egyptian Mediterranean coast. Journal of Applied Pharmaceutical Science, 9(7), 22-28.

Tocopheryl Acetate

Other name: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate

Function: Skin Conditioning, Antioxidant

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

Sodium Pca

Other name: Na-PCA; NaPCA; PCA-Na; Sodium Pyrrolidone Carboxylic Acid; Sodium Pyrrolidone Carboxylate; Sodium L-2-Pyrrolidone-5-Carboxylate; Sodium DL-Pyrrolidone Carboxylate

Function: Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Polyacrylamide

Other name: Polyacryamide

Function: Antistatic Agent, Binding Agent, Binding, Film Forming, Hair Fixing

1. Definition Polyacrylamide:

Polyacrylamide is a synthetic polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and film-former. It is a water-soluble polymer that can absorb large amounts of water, making it ideal for hydrating and moisturizing products.

2. Use:

Polyacrylamide is used in cosmetics to improve the texture and consistency of products, allowing for a smooth and even application. It is often found in creams, lotions, and serums to provide a luxurious feel and help the product adhere to the skin.

3. Usage Polyacrylamide:

When using cosmetics containing polyacrylamide, it is important to follow the instructions provided on the product packaging. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid getting the product in the eyes, mouth, or any open wounds.

4. References:

- Fiume, M. M., Heldreth, B. A., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2014). Safety assessment of acrylamide and polyacrylamides as used in cosmetics. International journal of toxicology, 33(2_suppl), 3S-22S.

- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of polyacrylamide. International journal of toxicology, 24(2_suppl), 21-50.

- Lode, O., & Dufour, P. (2012). Polyacrylamides in cosmetics: a risk for human health?. Contact dermatitis, 66(6), 330-331.

C13 14 Isoparaffin

Function: Solvent, Emollient

1. Definition C13 14 Isoparaffin:

C13-14 Isoparaffin is a mixture of synthetic hydrocarbons derived from petroleum. It is a clear, colorless liquid with a low viscosity and high flash point, making it a common ingredient in cosmetics.

2. Use:

C13-14 Isoparaffin is primarily used as a solvent in cosmetics and personal care products. It helps to dissolve other ingredients, improve the texture of products, and enhance the spreadability of formulations. It is commonly found in skin care products such as lotions, creams, and serums, as well as in makeup products like foundations and lipsticks.

3. Usage C13 14 Isoparaffin:

When using products containing C13-14 Isoparaffin, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, and discontinue use if any irritation or adverse reaction occurs. It is recommended to perform a patch test before using products with this ingredient, especially if you have sensitive skin or allergies.

4. References:

- "Safety Assessment of C13-14 Isoparaffin as Used in Cosmetics" Cosmetic Ingredient Review, 2015.

- "Isoparaffin" Cosmetics Info, https://cosmeticsinfo.org/ingredient/isoparaffin

- "C13-14 Isoparaffin" The Dermatology Review, https://thedermreview.com/c13-14-isoparaffin/

Laureth 7

Function: Emulsifying, Surfactant

1. Definition Laureth 7:

Laureth 7 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics as an emulsifier and surfactant. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth 7 is used in a variety of cosmetic products such as cleansers, shampoos, conditioners, and lotions. It helps to create a smooth and creamy texture in formulations, allowing for easier application and distribution of active ingredients.

3. Usage Laureth 7:

When using products containing Laureth 7, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Laureth 7 to ensure they do not experience any adverse reactions. It is also recommended to avoid getting Laureth 7 in the eyes, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Laureth-7. https://cosmeticsinfo.org/ingredient/laureth-7

- Personal Care Council. (2007). Safety Assessment of Laureth-7 and PEG-7 Laureate. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr110.pdf

- U.S. National Library of Medicine. (2021). Laureth-7. https://pubchem.ncbi.nlm.nih.gov/compound/Laureth-7

Sorbitol

Other name: D-Glucitol

Function: Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

Tridecyl Trimellitate

Function: Skin Conditioning, Emollient

1. Definition Tridecyl Trimellitate:

Tridecyl Trimellitate is a synthetic ester derived from trimellitic anhydride and tridecyl alcohol. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Tridecyl Trimellitate is used in a variety of cosmetic products such as lipsticks, lip balms, and skincare creams. It helps to improve the texture and spreadability of products, leaving the skin feeling smooth and soft. Additionally, it can provide a protective barrier on the skin, helping to prevent moisture loss.

3. Usage Tridecyl Trimellitate:

Tridecyl Trimellitate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before using products containing this ingredient to ensure compatibility with your skin. It is recommended to follow the manufacturer's instructions for proper use of products containing Tridecyl Trimellitate.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Tridecyl Trimellitate." International Journal of Toxicology, vol. 22, no. S2, 2003, pp. 1-10.

- "Tridecyl Trimellitate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/tridecyl-trimellitate.

- "Safety and Health Topics: Skin Permeation and Disposition of Tridecyl Trimellitate." Occupational Safety and Health Administration, www.osha.gov/dts/chemicalsampling/data/CH_273300.html.

Urea

Other name: Carbonyl diamide; Carbamide

Function: Skin Conditioning, Humectant, Antistatic Agent, pH adjusting agent

1. Definition Urea:

Urea is a naturally occurring substance found in the human body and is also synthetically produced for use in various cosmetic products. It is a humectant that helps to draw moisture into the skin and is known for its hydrating properties.

2. Use:

Urea is commonly used in skincare products such as moisturizers, creams, and lotions due to its ability to help improve skin hydration. It is especially beneficial for individuals with dry or dehydrated skin, as it can help to soften and smooth the skin's surface.

3. Usage Urea:

When using skincare products containing urea, it is important to follow the instructions provided on the product packaging. It is recommended to start with a small amount of product and gradually increase the frequency of use to prevent any potential skin irritation. Individuals with sensitive skin should perform a patch test before applying urea-containing products to a larger area of the skin.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Loden, M., & Maibach, H. I. (2005). Dry skin and moisturizers: chemistry and function. CRC Press.

Trehalose

Function: Humectant, Moisturising, Flavoring Agent

1. Definition Trehalose:

Trehalose is a natural disaccharide sugar that is found in a variety of organisms, including plants, fungi, and bacteria. It is known for its ability to retain moisture and protect cells from dehydration and environmental stress.

2. Use:

Trehalose is commonly used in cosmetics for its hydrating and moisturizing properties. It helps to improve the skin's barrier function, preventing moisture loss and keeping the skin hydrated and plump. Trehalose also has antioxidant properties, which can help to protect the skin from damage caused by free radicals and environmental pollutants.

3. Usage Trehalose:

Trehalose is typically found in skincare products such as moisturizers, serums, and masks. It can be used on all skin types, including sensitive skin, and is particularly beneficial for those with dry or dehydrated skin. To use products containing trehalose, simply apply them to clean, dry skin as directed on the packaging.

4. References:

- Yoon, H. S., Cho, H. H., Kim, M. H., & Lee, S. R. (2019). The clinical efficacy of a facial essence containing Trehalose on skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 31(2), 206-211.

- Chen, L., Zhang, Z., Chen, W., & Zhang, Z. (2018). Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway. Scientific Reports, 8(1), 1-11.

- Kim, J. H., Baek, S. H., Lee, H. J., & Kim, M. R. (2015). Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance. Nutrition Research and Practice, 9(3), 249-256.

Polyquaternium 51

Other name: Lipidure-PMB

Function: Skin Conditioning, Humectant, Film Forming

1. Definition Polyquaternium 51:

Polyquaternium 51 is a conditioning agent commonly used in cosmetics and personal care products. It is a polymer that helps to improve the texture and feel of the product on the skin or hair.

2. Use:

Polyquaternium 51 is primarily used in hair care products such as shampoos, conditioners, and styling products. It helps to smooth the hair cuticle, reduce frizz, and enhance shine. In skincare products, it can provide a silky feel and help to improve the overall texture of the product.

3. Usage Polyquaternium 51:

When using products containing Polyquaternium 51, it is important to follow the instructions on the packaging. It is generally safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is also important to avoid getting the product in the eyes, as it may cause irritation.

4. References:

- "Polyquaternium-51." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyquaternium-51.

- "Polyquaternium-51." The Derm Review, www.thedermreview.com/polyquaternium-51/.

- "Polyquaternium-51." Truth In Aging, www.truthinaging.com/ingredients/polyquaternium-51.

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Carbomer

Other name: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Diazolidinyl Urea

Other name: Germall II; Liposerve DU; Germall Ⅱ

Function: Preservative

1. Definition Diazolidinyl Urea:

Diazolidinyl Urea is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria, yeast, and mold. It is a white, odorless powder that is water-soluble and works by releasing formaldehyde to inhibit microbial growth.

2. Use:

Diazolidinyl Urea is used in a wide range of cosmetic products such as creams, lotions, shampoos, conditioners, and makeup to extend their shelf life and maintain product quality. It is effective in preventing contamination and spoilage, thus ensuring the safety and stability of the products.

3. Usage Diazolidinyl Urea:

When using products containing Diazolidinyl Urea, it is important to follow the recommended usage guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 0.5%, depending on the formulation and intended use of the product. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this preservative.

4. References:

- Cosmetic Ingredient Review (CIR). (2006). Final Report on the Safety Assessment of Diazolidinyl Urea. Retrieved from https://www.cir-safety.org/sites/default/files/diazolidinyl%20urea.pdf

- Personal Care Council. (2019). Diazolidinyl Urea. Retrieved from https://www.personalcarecouncil.org/ingredient-info/diazolidinyl-urea/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=700.10

Iodopropynyl Butylcarbamate

Other name: 3-Iodo-2-Propynyl Butyl Carbamate; IPBC; Biodocarb C450

Function: Preservative

1. Definition Iodopropynyl Butylcarbamate:

Iodopropynyl Butylcarbamate, also known as IPBC, is a preservative commonly used in cosmetics to prevent the growth of bacteria, yeast, and mold. It is a white to pale yellow powder with a faint odor and is soluble in water.

2. Use:

IPBC is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, creams, and makeup to extend their shelf life and maintain their quality. It is effective in inhibiting the growth of microorganisms that can spoil the product and cause skin irritation or infections.

3. Usage Iodopropynyl Butylcarbamate:

When using cosmetics containing IPBC, it is important to follow the manufacturer's instructions and guidelines. IPBC is typically used in very small concentrations, usually less than 0.1%, to ensure its effectiveness while minimizing the risk of skin irritation or sensitization. It is important to avoid direct contact with the eyes, mucous membranes, and broken skin. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of iodopropynyl butylcarbamate. Int J Toxicol. 1995;14 Suppl 1:31-54.

- Cosmetic Ingredient Review Expert Panel. Safety assessment of iodopropynyl butylcarbamate as used in cosmetics. Int J Toxicol. 2010 Jan;29(1 Suppl):182S-202S.

- U.S. Food and Drug Administration. Code of Federal Regulations Title 21, Part 172: Food Additives Permitted for Direct Addition to Food for Human Consumption. Accessed online at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.210

Tetrasodium Edta

Other name: EDTA-4Na; Tetrasodium ethylenediaminetetraacetate

Function: Chelating Agent

1. Definition Tetrasodium Edta:

Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.

2. Use:

Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.

3. Usage Tetrasodium Edta:

Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

Blue 1

Other name: Brillant blue FCF; Brilliant blue FCF; CI 42090; FD&C Blue 1 Aluminium Lake; FD&C Blue #1; Food Blue 2; Blue 1; Blue 1 Lake; Acid blue 9; Erioglaucine A; Acid Blue 9 Aluminum Lake

Function:

1. Definition Blue 1:

Blue 1, also known as FD&C Blue No. 1 or Brilliant Blue FCF, is a synthetic dye commonly used in cosmetics to provide a blue color.

2. Use:

Blue 1 is primarily used as a colorant in various cosmetic products such as eyeshadows, lipsticks, nail polishes, and hair dyes. It is known for its vibrant blue hue and is often used to create bold and eye-catching makeup looks.

3. Usage Blue 1:

Blue 1 is considered safe for use in cosmetics by regulatory bodies such as the Food and Drug Administration (FDA) in the United States and the European Union. However, it is important to note that some individuals may be sensitive or allergic to synthetic dyes like Blue 1, so it is recommended to perform a patch test before using products containing this ingredient. Additionally, it is advisable to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of FD&C Blue No. 1. International Journal of Toxicology. 2002;21(Suppl 3):15-41.

- Food and Drug Administration (FDA). Color Additives Permitted for Use in Cosmetics. Accessed from: https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics

- European Commission. CosIng Database. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/