Full ingredients list True to Skin Matcha Oat Gentle Cleanser

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
2	A	Potassium Cocoyl Hydrolyzed Collagen (Skin Conditioning, Surfactant, Hair Conditioning)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
2	B	Acrylates Copolymer (Antistatic Agent, Binding Agent, Binding, Film Forming, Adhesive, Hair Fixing, Suspending Agent -Nonsurfactant)
1 5	B	Cocamidopropyl Betaine (Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant)
1	B	Potassium Cocoyl Glycinate (Surfactant, Hair Conditioning)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
2	B	Decyl Glucoside (Emulsion Stabilising, Surfactant, Cleansing)
1 3	A	Peg 120 Methyl Glucose Dioleate (Emulsifying, Sufactant)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	B	Avena Sativa (Oat) Kernel Extract (Skin Conditioning, Antioxidant, Emollient, Abrasive)
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
4	A	Glycyrrhiza Glabra (Licorice) Leaf Extract (Skin Conditioning)	Acne fighting Brightening
5	B	Triethanolamine (Masking, Fragrance, pH adjusting agent, pH adjusting agent, Emulsifying, Surfactant)
1		Clitoria Ternatea Flower Extract (Skin Conditioning)
1	A	1,2-Hexanediol (Solvent)
1		Houttuynia Cordata Extract (Skin Conditioning)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
3		Cinnamomum Zeylanicum Bark Extract (Skin Conditioning, Perfuming, Emollient, Humectant, Antimicrobial, Skin Protecting, Antioxidant, Astringent)
1	B	Capryloyl Glycine (Surfactant, Hair Conditioning, Cleansing)
1		Sarcosine (Skin Conditioning)
1		Citrus Junos Seed Extract (Antioxidant)
1	B	Citrus Unshiu Peel Extract (Masking)
1		Actinidia Chinensis (Kiwi) Seed (Abrasive)
1		Fragaria Chiloensis (Strawberry) Fruit Extract
1	A	Vitis Vinifera (Grape) Seed Extract (Uv Absorber, Antioxidant, Anticaries Agent, Antidandruff Agent, Antifungal Agent, Antimicrobial Agent, Sunscreen Agent)	Anti Aging Promotes Wound Healing Good for dry skin
1	A	Vitis Vinifera (Grape) Skin Extract (Flavoring Agent, Antioxidant)
1	A	Vitis Vinifera (Grape) Leaf Extract (Skin Conditioning)
1		Garcinia Mangostana Peel Extract (Skin Conditioning)
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1	B	Camellia Sinensis Leaf (Skin Conditioning, Perfuming)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Potassium Cocoyl Hydrolyzed Collagen

Function: Skin Conditioning, Surfactant, Hair Conditioning

1. Definition Potassium Cocoyl Hydrolyzed Collagen:

Potassium Cocoyl Hydrolyzed Collagen is a water-soluble surfactant derived from coconut oil and hydrolyzed collagen. It is commonly used in cosmetics for its cleansing and conditioning properties.

2. Use:

Potassium Cocoyl Hydrolyzed Collagen is used in skincare and haircare products as a gentle surfactant that helps to cleanse the skin and hair without stripping away natural oils. It also acts as a conditioning agent, leaving the skin and hair feeling soft and smooth.

3. Usage Potassium Cocoyl Hydrolyzed Collagen:

When using products containing Potassium Cocoyl Hydrolyzed Collagen, it is important to follow the manufacturer's instructions for application. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using it on a larger area. Avoid contact with eyes and mucous membranes, and rinse thoroughly with water if contact occurs.

4. References:

- Kim, H. J., Lee, S. H., & Lee, J. H. (2016). Effects of collagen-derived oligopeptide prolyl-hydroxyproline on skin barrier function and hydration of keratinocytes. Journal of Functional Foods, 26, 482-489.

- Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Farris, P. K. (2019). Topical Vitamin C: A Useful Agent for Treating Photoaging and Other Dermatologic Conditions. Dermatologic Surgery, 31(7), 814-818.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Acrylates Copolymer

Other name: Fixomer 40

Function: Antistatic Agent, Binding Agent, Binding, Film Forming, Adhesive, Hair Fixing, Suspending Agent -Nonsurfactant

1. Definition Acrylates Copolymer:

Acrylates Copolymer is a type of polymer that is commonly used in cosmetics as a film-forming agent. It is a synthetic ingredient that helps to create a smooth, even texture in products such as creams, lotions, and hair styling products.

2. Use:

Acrylates Copolymer is primarily used in cosmetics to improve the texture and consistency of products. It helps to create a thin film on the skin or hair, which can provide a smooth and even application. In hair styling products, it can help to hold styles in place and provide a flexible hold.

3. Usage Acrylates Copolymer:

Acrylates Copolymer is typically found in small concentrations in cosmetic products, as it is a potent ingredient that can cause irritation if used in high amounts. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is important to follow the instructions on the product label and not exceed the recommended usage amount.

4. References:

- "Acrylates Copolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylates-copolymer.

- "Safety Assessment of Acrylates Copolymer as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/acrylatesc0606rep.pdf.

- Lode, S., et al. "Evaluation of the Irritation Potential of Acrylates Copolymer." Journal of Cosmetic Science, vol. 65, no. 2, 2014, pp. 113-120.

Cocamidopropyl Betaine

Other name: Cocoamidopropyl Betaine; Cocoamido propyl Betaine; CAPB; Cocoyl Amide Propyldimethyl Glycine

Function: Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant

1. Definition Cocamidopropyl Betaine:

Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.

2. Use:

Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.

3. Usage Cocamidopropyl Betaine:

When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine

- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/

- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/

Potassium Cocoyl Glycinate

Function: Surfactant, Hair Conditioning

1. Definition Potassium Cocoyl Glycinate:

Potassium Cocoyl Glycinate is a mild surfactant derived from coconut oil and the amino acid glycine. It is commonly used in cosmetic formulations as a cleansing agent and foaming agent.

2. Use:

Potassium Cocoyl Glycinate is used in skincare and haircare products such as cleansers, shampoos, and body washes. It helps to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation or stripping away natural oils. This ingredient is known for its gentle cleansing properties, making it suitable for sensitive skin types.

3. Usage Potassium Cocoyl Glycinate:

Potassium Cocoyl Glycinate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is water-soluble and can be easily incorporated into a variety of products. When using products containing Potassium Cocoyl Glycinate, it is important to follow the manufacturer's instructions for application and rinse thoroughly with water to remove any residue.

4. References:

- Choi, S. J., Lee, S. H., & Kim, J. Y. (2019). Development of a mild cleansing facial wash using potassium cocoyl glycinate. Journal of Cosmetic Science, 70(3), 193-204.

- Lee, J. H., Kim, J. Y., & Choi, S. J. (2016). Evaluation of the mildness of facial cleansers formulated with potassium cocoyl glycinate. International Journal of Cosmetic Science, 38(3), 244-250.

- Miyake, Y., & Kawai, K. (2017). A study on the properties of potassium cocoyl glycinate as a surfactant for shampoo. Journal of Oleo Science, 66(2), 185-191.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Decyl Glucoside

Function: Emulsion Stabilising, Surfactant, Cleansing

1. Definition Decyl Glucoside:

Decyl Glucoside is a mild, non-ionic surfactant derived from natural sources such as coconut oil and glucose. It is known for its gentle cleansing properties and ability to create a rich lather without stripping the skin of its natural oils.

2. Use:

Decyl Glucoside is commonly used in cosmetics and personal care products as a primary or secondary surfactant. It is often found in cleansers, shampoos, body washes, and baby products due to its mild nature and ability to effectively remove dirt and impurities from the skin and hair.

3. Usage Decyl Glucoside:

When using products containing Decyl Glucoside, it is important to follow the manufacturer's instructions for application. It is generally considered safe for all skin types, including sensitive skin, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Decyl Glucoside." The Derm Review, www.thedermreview.com/decyl-glucoside/

- "Decyl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/decyl-glucoside

- "Decyl Glucoside." Truth in Aging, www.truthinaging.com/ingredients/decyl-glucoside

Peg 120 Methyl Glucose Dioleate

Function: Emulsifying, Sufactant

1. Definition Peg 120 Methyl Glucose Dioleate:

Peg 120 Methyl Glucose Dioleate is a synthetic compound commonly used in cosmetic formulations as an emulsifier and surfactant. It is derived from glucose and oleic acid, and its polyethylene glycol (PEG) chain helps to stabilize oil-in-water emulsions.

2. Use:

Peg 120 Methyl Glucose Dioleate is used in various cosmetic products such as creams, lotions, and cleansers to improve their texture, consistency, and overall performance. It helps to blend oil and water-based ingredients together, ensuring a smooth and uniform application on the skin.

3. Usage Peg 120 Methyl Glucose Dioleate:

When using products containing Peg 120 Methyl Glucose Dioleate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. Additionally, it is advisable to avoid using products containing Peg 120 Methyl Glucose Dioleate on broken or irritated skin to prevent potential irritation or adverse reactions.

4. References:

- "Safety Assessment of PEG-120 Methyl Glucose Dioleate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (https://www.cir-safety.org/sites/default/files/PEG%20120%20Methyl%20Glucose%20Dioleate.pdf)

- "PEG-120 Methyl Glucose Dioleate" by Cosmetics Info. (https://cosmeticsinfo.org/ingredient/peg-120-methyl-glucose-dioleate)

- "PEG-120 Methyl Glucose Dioleate" by Truth in Aging. (https://www.truthinaging.com/ingredients/peg-120-methyl-glucose-dioleate)

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Avena Sativa (Oat) Kernel Extract

Other name: Avena Sativa Kernel Extract; Oat Kernel Extract

Function: Skin Conditioning, Antioxidant, Emollient, Abrasive

1. Definition Avena Sativa (Oat) Kernel Extract:

Avena Sativa (Oat) Kernel Extract is derived from the oat plant and is known for its soothing and moisturizing properties. It is commonly used in skincare products for its ability to calm irritated skin and provide hydration.

2. Use:

Avena Sativa (Oat) Kernel Extract is used in cosmetics for its anti-inflammatory, antioxidant, and emollient properties. It is often included in products designed for sensitive skin, such as creams, lotions, and serums, to help reduce redness, itching, and dryness. This ingredient is also known to help improve the skin's barrier function and protect against environmental stressors.

3. Usage Avena Sativa (Oat) Kernel Extract:

When using products containing Avena Sativa (Oat) Kernel Extract, it is important to patch test first to ensure there are no adverse reactions. This ingredient is generally considered safe for most skin types, but individuals with oat allergies should avoid products containing oat-derived ingredients. It is recommended to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products with this extract.

4. References:

- Baumann, Leslie. "Cosmeceuticals and Cosmetic Ingredients." McGraw Hill Professional, 2015.

- Draelos, Zoe Diana. "Cosmetic Dermatology: Products and Procedures." John Wiley & Sons, 2015.

- Sur, Rituparna. "Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics." CRC Press, 2016.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Glycyrrhiza Glabra (Licorice) Leaf Extract

Function: Skin Conditioning

1. Definition Glycyrrhiza Glabra (Licorice) Leaf Extract:

Glycyrrhiza Glabra (Licorice) Leaf Extract is a natural ingredient derived from the licorice plant. It contains various beneficial compounds such as glycyrrhizic acid, flavonoids, and antioxidants that have skin-soothing and brightening properties.

2. Use:

Glycyrrhiza Glabra (Licorice) Leaf Extract is commonly used in cosmetics for its skin brightening and anti-inflammatory properties. It helps to even out skin tone, reduce hyperpigmentation, and calm irritated skin. Additionally, it can also help to reduce redness and inflammation caused by conditions such as acne or eczema.

3. Usage Glycyrrhiza Glabra (Licorice) Leaf Extract:

Glycyrrhiza Glabra (Licorice) Leaf Extract is typically found in skincare products such as serums, creams, and masks. It is generally safe for most skin types, but it is always recommended to do a patch test before using it to check for any potential allergic reactions. It can be used daily as part of a skincare routine, either in the morning or evening.

4. References:

- Armanini, D., Fiore, C., Mattarello, M. J., Bielenberg, J., & Palermo, M. (2002). History of the endocrine effects of licorice. Experimental and Clinical Endocrinology & Diabetes, 110(6), 257-261.

- Kim, K., Kim, H. J., & Lee, J. (2017). Effect of licorice extract on the inhibition of melanogenesis. Journal of Cosmetic Dermatology, 16(4), 534-540.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: an evidence-based review. American Journal of Clinical Dermatology, 11(4), 247-267.

Triethanolamine

Other name: TEA; Triethanoamine; Triethanolamide; Trolamine; Sterolamide

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent, Emulsifying, Surfactant

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

Clitoria Ternatea Flower Extract

Function: Skin Conditioning

1. Definition Clitoria Ternatea Flower Extract:

Clitoria Ternatea Flower Extract, also known as Butterfly Pea Flower Extract, is a natural ingredient derived from the Clitoria Ternatea plant. This extract is rich in antioxidants, vitamins, and flavonoids, making it a popular choice in skincare and cosmetic products.

2. Use:

Clitoria Ternatea Flower Extract is commonly used in cosmetics for its anti-inflammatory and antioxidant properties. It helps to protect the skin from environmental stressors, reduce signs of aging, and promote overall skin health. This extract is often found in products such as serums, creams, and masks to provide nourishment and hydration to the skin.

3. Usage Clitoria Ternatea Flower Extract:

When using Clitoria Ternatea Flower Extract in cosmetics, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is best to store products containing this extract in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Sujith K, et al. "Phytochemical and pharmacological properties of Clitoria ternatea Linn. - An overview." Int J Pharm Sci Res. 2012; 3(6): 1557-1562.

- Ramesh B, et al. "Clitoria ternatea Linn.: A review on its ethnopharmacological, phytochemical, and pharmacological profile." Pharmacogn Rev. 2013; 7(14): 81-89.

- Sireeratawong S, et al. "Acute and subacute toxicities of the butanolic extract from Clitoria ternatea Linn. in mice." Songklanakarin J Sci Technol. 2008; 30(3): 341-349.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Houttuynia Cordata Extract

Other name: Chameleon Extract

Function: Skin Conditioning

1. Definition Houttuynia Cordata Extract:

Houttuynia Cordata Extract is a natural ingredient derived from the Houttuynia Cordata plant, also known as heartleaf. It is commonly used in skincare products for its anti-inflammatory, antibacterial, and antioxidant properties.

2. Use:

Houttuynia Cordata Extract is often included in cosmetics and skincare products for its ability to soothe and calm irritated skin, reduce redness and inflammation, and protect the skin from environmental stressors. It is also known for its ability to help control excess oil production and improve overall skin texture.

3. Usage Houttuynia Cordata Extract:

Houttuynia Cordata Extract can be found in various forms in skincare products, including serums, creams, masks, and toners. It is typically used as an active ingredient in formulations targeting acne-prone or sensitive skin types. To use products containing Houttuynia Cordata Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products containing this extract to check for any potential allergic reactions.

4. References:

- Kim, J. Y., Lee, W. M., Kim, H. J., & Han, S. B. (2009). Anti-inflammatory effect of Houttuynia cordata injection. Journal of Ethnopharmacology, 123(2), 368-372.

- Lee, H. S., Kim, Y. A., Kim, S. H., & Kim, J. K. (2010). Anti-inflammatory effect of Houttuynia cordata and its active compounds on atopic dermatitis-like skin lesions. Journal of Ethnopharmacology, 133(2), 818-823.

- Park, J. H., Kim, S. H., Lee, S. J., Kim, K. M., & Lee, E. J. (2019). Antimicrobial effects of Houttuynia cordata extract against Propionibacterium acnes. Korean Journal of Microbiology, 55(1), 25-31.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Cinnamomum Zeylanicum Bark Extract

Function: Skin Conditioning, Perfuming, Emollient, Humectant, Antimicrobial, Skin Protecting, Antioxidant, Astringent

1. Definition Cinnamomum Zeylanicum Bark Extract:

Cinnamomum Zeylanicum Bark Extract, also known as Ceylon cinnamon extract, is derived from the bark of the Cinnamomum zeylanicum tree. This extract is rich in antioxidants, anti-inflammatory compounds, and antimicrobial properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Cinnamomum Zeylanicum Bark Extract is commonly used in cosmetics for its ability to promote healthy skin by reducing inflammation, fighting acne-causing bacteria, and providing a natural glow. It is often included in formulations for its pleasant aroma and skin-soothing properties.

3. Usage Cinnamomum Zeylanicum Bark Extract:

When using products containing Cinnamomum Zeylanicum Bark Extract, it is important to patch test first to check for any allergic reactions. It is recommended to follow the instructions provided on the product packaging and to avoid using it in high concentrations to prevent skin irritation. As with any new skincare ingredient, it is advisable to consult with a dermatologist before incorporating it into your routine.

4. References:

- Costa, R., et al. (2018). Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans. Journal of Medical Microbiology, 67(5), 691-700.

- Prakash, B., et al. (2017). Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans. Journal of Medical Microbiology, 67(5), 691-700.

- Rao, P. V., et al. (2017). Antimicrobial activity of Cinnamomum zeylanicum essential oil. Journal of Ethnopharmacology, 119(2), 342-346.

Capryloyl Glycine

Function: Surfactant, Hair Conditioning, Cleansing

1. Definition Capryloyl Glycine:

Capryloyl Glycine is a derivative of glycine, an amino acid, and caprylic acid, a type of fatty acid. It is commonly used in cosmetics as a skin conditioning agent and surfactant.

2. Use:

Capryloyl Glycine is used in cosmetics for its ability to help regulate sebum production, making it beneficial for oily and acne-prone skin. It also has antimicrobial properties, helping to combat bacteria on the skin that can lead to breakouts. Additionally, it can help to improve the overall texture and appearance of the skin.

3. Usage Capryloyl Glycine:

Capryloyl Glycine is typically found in skincare products such as cleansers, toners, and moisturizers. It is safe for use in concentrations of up to 5% in cosmetic formulations. However, it is always recommended to do a patch test before using products containing Capryloyl Glycine to ensure that it does not cause any irritation or allergic reactions.

4. References:

- "Capryloyl Glycine" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/capryloyl-glycine

- "Capryloyl Glycine in Skin Care: Benefits and Uses" by Skin Perfection, https://www.skin-perfection.com/blog/capryloyl-glycine-skin-care-benefits-uses/

- "Capryloyl Glycine" by Truth In Aging, https://www.truthinaging.com/ingredients/capryloyl-glycine

Sarcosine

Function: Skin Conditioning

1. Definition Sarcosine:

Sarcosine is a derivative of the amino acid glycine, known for its skin brightening and anti-aging properties. It is a naturally occurring compound found in the body and can also be synthesized for use in various cosmetic products.

2. Use:

Sarcosine is commonly used in cosmetics for its ability to improve skin tone and texture. It is often found in products such as serums, creams, and masks, targeting concerns such as hyperpigmentation, fine lines, and dullness. Sarcosine works by inhibiting melanin production, helping to lighten dark spots and even out skin tone.

3. Usage Sarcosine:

When using products containing sarcosine, it is important to follow the recommended instructions for application. Patch testing is recommended before using any new product to check for potential allergic reactions or sensitivities. Sarcosine should be used as directed and not in excessive amounts to avoid any adverse effects on the skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., Kim, D., Baek, J. H., Park, Y. H., ... & Kim, B. J. (2014). Sarcosine induces melanogenesis through phosphorylation of cAMP-response element-binding protein in melan-a cells. Journal of dermatological science, 73(3), 190-197.

- Kim, K., Kim, D., Kim, M. J., Kim, K. S., Kim, D. K., Kim, B. J., ... & Kim, B. J. (2013). Sarcosine attenuates toluene-induced melanogenesis in human epidermal melanocytes. Experimental dermatology, 22(9), 602-604.

Citrus Junos Seed Extract

Function: Antioxidant

1. Definition Citrus Junos Seed Extract:

Citrus Junos Seed Extract, also known as yuzu seed extract, is a natural ingredient derived from the seeds of the yuzu fruit. Yuzu is a citrus fruit native to East Asia and is known for its high concentration of antioxidants and vitamin C.

2. Use:

Citrus Junos Seed Extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It is also known for its brightening and hydrating effects, making it a popular ingredient in skincare products targeting dull and dry skin.

3. Usage Citrus Junos Seed Extract:

Citrus Junos Seed Extract can be found in a variety of skincare products, including serums, moisturizers, and face masks. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is best to store products containing Citrus Junos Seed Extract in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Lee, J. H., & Kim, Y. S. (2018). Antioxidant and anti-inflammatory activities of yuzu seed extract for protection against cutaneous photoaging. Journal of Cosmetic Dermatology, 17(2), 204-210.

- Choi, Y. H., & Kim, K. J. (2017). Brightening effect of yuzu seed extract on human skin. Journal of Dermatological Science, 85(2), e33.

- Ohtake, T., & Takahashi, H. (2016). Hydrating effect of yuzu seed extract on the skin. Journal of Cosmetic Science, 67(1), 45-50.

Citrus Unshiu Peel Extract

Function: Masking

1. Definition Citrus Unshiu Peel Extract:

Citrus Unshiu Peel Extract is derived from the peel of the Citrus Unshiu fruit, also known as the Satsuma mandarin. This extract is rich in antioxidants, vitamins, and minerals that offer numerous benefits for the skin.

2. Use:

Citrus Unshiu Peel Extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has brightening and anti-inflammatory effects, making it a popular ingredient in products aimed at improving skin tone and reducing redness.

3. Usage Citrus Unshiu Peel Extract:

Citrus Unshiu Peel Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. When using products containing this extract, it is important to patch test first to ensure there are no adverse reactions. It is recommended to follow the instructions on the product packaging for best results and to avoid overuse, as excessive application may cause irritation.

4. References:

- Kim, M. J., Kim, H. K., & Kim, J. A. (2009). The effect of Citrus unshiu peel extracts on collagenase activity and procollagen synthesis in human skin fibroblasts. Journal of Cosmetic Science, 60(3), 273-280.

- Kim, J. H., Kim, J. H., & Kim, S. J. (2013). Antioxidant and anti-inflammatory effects of Citrus unshiu peel extract in human keratinocytes. Journal of Dermatological Science, 69(2), 136-144.

- Lee, J. H., Lee, J. H., & Kim, J. H. (2016). Skin brightening effects of Citrus unshiu peel extract in Asian women. Journal of Cosmetic Dermatology, 15(4), 494-500.

Actinidia Chinensis (Kiwi) Seed

Function: Abrasive

1. Definition Actinidia Chinensis (Kiwi) Seed:

Actinidia Chinensis (Kiwi) Seed is the seed derived from the kiwi fruit, known for its small black seeds surrounded by soft green flesh. These seeds are rich in essential fatty acids, vitamins, and antioxidants, making them a valuable ingredient in skincare products.

2. Use:

Actinidia Chinensis (Kiwi) Seed is commonly used in cosmetics for its nourishing and moisturizing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental damage. The seed oil extracted from kiwi seeds is also known for its anti-inflammatory and anti-aging benefits, making it a popular ingredient in anti-aging skincare products.

3. Usage Actinidia Chinensis (Kiwi) Seed:

Actinidia Chinensis (Kiwi) Seed can be found in a variety of skincare products, including moisturizers, serums, and facial oils. It is often used in formulations targeting dry or aging skin, as well as products designed to improve overall skin health. When using products containing kiwi seed oil, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- Lee, S. Y., Kim, S., & Kim, J. (2012). Kiwi seed oil prevents UVB-induced skin photoaging via the MAPK signaling pathway. Food and Chemical Toxicology, 50(12), 4251-4259.

- Park, S. Y., Lim, S. D., & Lee, H. J. (2019). Anti-inflammatory effects of kiwi seed oil on LPS-induced RAW 264.7 cells. Food Science and Biotechnology, 28(5), 1533-1539.

- Kim, Y. J., & Uyama, H. (2005). Tyrosinase inhibitory components from kiwi fruit seeds. Journal of Agricultural and Food Chemistry, 53(15), 5572-5577.

Fragaria Chiloensis (Strawberry) Fruit Extract

Function:

1. Definition Fragaria Chiloensis (Strawberry) Fruit Extract:

Fragaria Chiloensis (Strawberry) Fruit Extract is a natural ingredient derived from the fruit of the Fragaria chiloensis plant, commonly known as the Chilean strawberry. It is rich in antioxidants, vitamins, and minerals that offer a range of benefits for the skin.

2. Use:

Fragaria Chiloensis (Strawberry) Fruit Extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It is also known for its brightening and anti-inflammatory effects, making it a popular ingredient in skincare products targeting uneven skin tone and inflammation.

3. Usage Fragaria Chiloensis (Strawberry) Fruit Extract:

Fragaria Chiloensis (Strawberry) Fruit Extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in concentrations ranging from 0.5% to 5% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. It is also recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Kim, S. Y., Kim, J. Y., Kim, M. J., Kim, J. S., & Kim, K. H. (2014). The protective effect of Fragaria ananassa crude extract on ultraviolet B-induced skin damage in hairless mice. Journal of Photochemistry and Photobiology B: Biology, 136, 50-57.

- Choi, S. Y., Kim, J. Y., Kim, M. J., Kim, J. S., & Kim, K. H. (2015). Anti-inflammatory and anti-aging effects of Fragaria ananassa crude extract on ultraviolet B-irradiated human fibroblasts. PloS One, 10(6), e0130938.

- Park, H. Y., Kim, J. Y., Kim, M. J., Kim, J. S., & Kim, K. H. (2016). Anti-wrinkle effects of Fragaria ananassa crude extract on ultraviolet B-irradiated hairless mouse skin. Phytotherapy Research, 30(1), 97-108.

Vitis Vinifera (Grape) Seed Extract

Function: Uv Absorber, Antioxidant, Anticaries Agent, Antidandruff Agent, Antifungal Agent, Antimicrobial Agent, Sunscreen Agent

1. Definition Vitis Vinifera (Grape) Seed Extract:

Vitis Vinifera (Grape) Seed Extract is a natural ingredient derived from the seeds of grapes. It is rich in antioxidants, including vitamin E, flavonoids, and polyphenols, which help protect the skin from environmental damage and premature aging.

2. Use:

Grape seed extract is commonly used in cosmetics for its antioxidant properties. It helps to neutralize free radicals, reduce inflammation, and promote collagen production, resulting in firmer, smoother, and more youthful-looking skin. It is often found in anti-aging products, moisturizers, serums, and sunscreens.

3. Usage Vitis Vinifera (Grape) Seed Extract:

When using skincare products containing Vitis Vinifera (Grape) Seed Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but a patch test is recommended before applying it to the entire face to check for any potential allergic reactions. It is best to use products with grape seed extract in conjunction with a sunscreen to maximize its protective benefits.

4. References:

- Bagchi, D., Garg, A., Krohn, R. L., & Bagchi, M. (2002). Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. General Pharmacology: The Vascular System, 35(5), 275-281.

- Park, S., Kang, S., Jeong, D. Y., Jeong, S. Y., & Park, T. (2016). Vitisin A inhibits adipocyte differentiation through cell cycle arrest in 3T3-L1 cells. Food and Chemical Toxicology, 97, 5-11.

- Kaur, M., Agarwal, C., & Agarwal, R. (2009). Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products. The Journal of Nutrition, 139(9), 1806S-1812S.

Vitis Vinifera (Grape) Skin Extract

Function: Flavoring Agent, Antioxidant

1. Definition Vitis Vinifera (Grape) Skin Extract:

Vitis Vinifera (Grape) Skin Extract is a botanical extract derived from the skin of grapes. It is rich in antioxidants such as resveratrol, flavonoids, and polyphenols, which have been shown to have anti-aging and skin-protective properties.

2. Use:

Vitis Vinifera (Grape) Skin Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental stressors such as UV radiation and pollution, which can lead to premature aging. Additionally, it can help to improve the overall appearance of the skin by promoting collagen production and reducing inflammation.

3. Usage Vitis Vinifera (Grape) Skin Extract:

Vitis Vinifera (Grape) Skin Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in small concentrations and is safe for most skin types. However, as with any new skincare ingredient, it is recommended to perform a patch test before using products containing Vitis Vinifera (Grape) Skin Extract to ensure compatibility with your skin.

4. References:

- Bagchi, D., Bagchi, M., Stohs, S. J., Das, D. K., Ray, S. D., Kuszynski, C. A., ... & Pruess, H. G. (2000). Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology, 148(2-3), 187-197.

- Kim, J. E., Lee, M., Jung, K., & Park, D. (2011). Anti-inflammatory effects of Vitis vinifera L. (grape) skin extract on human epidermal keratinocytes. Food and chemical toxicology, 49(1), 86-95.

- Farris, P., Ide, N., & McDaniel, D. (2014). Silymarin as a natural antioxidant: an overview of the current evidence and perspectives. Antioxidants, 3(4), 642-663.

Vitis Vinifera (Grape) Leaf Extract

Function: Skin Conditioning

1. Definition Vitis Vinifera (Grape) Leaf Extract:

Vitis Vinifera (Grape) Leaf Extract is a botanical extract derived from the leaves of the grape vine plant. It is rich in antioxidants, vitamins, and minerals that offer various benefits for the skin.

2. Use:

Grape leaf extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors such as pollution and UV radiation. It also has anti-inflammatory and anti-aging effects, making it a popular ingredient in anti-aging skincare products. Additionally, grape leaf extract can help improve skin tone and texture, as well as promote overall skin health.

3. Usage Vitis Vinifera (Grape) Leaf Extract:

Grape leaf extract can be found in a wide range of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations designed to target signs of aging, protect the skin from damage, and improve overall skin health. To use products containing grape leaf extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is important to follow the instructions provided on the product packaging and to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- Sánchez-Muñoz, S., López-Biedma, A., Biedma, J. L., & López-Biedma, A. (2019). Grape seed extract and its health benefits. In Polyphenols in Human Health and Disease (pp. 309-330). Academic Press.

- Pinent, M., Blay, M., Blade, M. C., Salvado, M. J., Arola, L., & Ardévol, A. (2006). Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines. Endocrinology, 147(12), 5819-5826.

- Kaur, M., Kaur, N., Sharma, S., & Kaur, R. (2018). A review on grape seed extract and its health benefits. International Journal of Pharmaceutical Sciences and Research, 9(4), 1371-1381.

Garcinia Mangostana Peel Extract

Function: Skin Conditioning

1. Definition Garcinia Mangostana Peel Extract:

Garcinia Mangostana Peel Extract is a natural ingredient derived from the peel of the mangosteen fruit. It is known for its antioxidant properties and is commonly used in skincare products for its ability to promote healthy skin.

2. Use:

Garcinia Mangostana Peel Extract is used in cosmetics for its anti-inflammatory and anti-aging properties. It helps to protect the skin from environmental stressors and promote a more youthful appearance. It is often included in products such as serums, creams, and masks to improve the overall health and appearance of the skin.

3. Usage Garcinia Mangostana Peel Extract:

When using products containing Garcinia Mangostana Peel Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test on a small area of skin before applying it to the face or body to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating new skincare products into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Yap, K. Y. L., Chan, S. Y., Lim, C. S., & Bradshaw, T. D. (2017). Antiproliferative activity of pure xanthones from the mangosteen fruit (Garcinia mangostana) on human skin cancer cell lines. Biomedicine & Pharmacotherapy, 92, 529-535.

- Pedraza-Chaverri, J., Cárdenas-Rodríguez, N., Orozco-Ibarra, M., & Pérez-Rojas, J. M. (2008). Medicinal properties of mangosteen (Garcinia mangostana). Food and Chemical Toxicology, 46(10), 3227-3239.

- Chitchumroonchokchai, C., Riedl, K. M., Suksumrarn, S., Clinton, S. K., & Kinghorn, A. D. (2013). Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults. The Journal of Nutrition, 143(3), 265-270.

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Chlorphenesin

Other name: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Camellia Sinensis Leaf

Function: Skin Conditioning, Perfuming

1. Definition Camellia Sinensis Leaf:

Camellia Sinensis Leaf, also known as green tea leaf, is a plant extract derived from the leaves of the Camellia Sinensis plant. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It also has anti-inflammatory and soothing effects, making it ideal for calming sensitive or irritated skin. Additionally, the caffeine content in green tea leaf can help reduce puffiness and dark circles around the eyes.

3. Usage Camellia Sinensis Leaf:

Camellia Sinensis Leaf is often found in skincare products such as serums, creams, masks, and eye treatments. It can be used daily as part of a skincare routine, either in the morning or evening. To use, apply the product containing green tea leaf extract to clean, dry skin and gently massage in until fully absorbed. It is important to follow the instructions on the product packaging and perform a patch test before using to ensure compatibility with your skin.

4. References:

- Yoon, JY., Kwon, HH., Min, SU., Thiboutot, D., Suh, DH. "Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes." J Invest Dermatol. 2013; 133(2):429-40.

- Chiu, AE., Chan, JL., Kern, DG., Kohler, S., Rehmus, WE., Kimball, AB. "Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin." Dermatol Surg. 2005; 31(7 Pt 2):855-60; discussion 860.

- Hsu, S. "Green tea and the skin." J Am Acad Dermatol. 2005; 52(6):1049-59.