Full ingredients list Tutare Serum Rosácea Microbiome Balance

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Simmondsia Chinensis (Jojoba) Seed Oil Extract (Skin Conditioning, Emollient, Hair Conditioning, Abrasive)
1		Calophyllum Inophyllum Oil
1	A	Borago Officinalis (Borage) Seed Oil (Skin Conditioning, Emollient)	Fungal Acne Trigger
		Salvia Hispanica (Chia) Oil
1	A	Helianthus Annuus (Sunflower) Seed Oil	Fungal Acne Trigger
		Lactobacillus/Salix Alba Bark Ferment Filtrate
1		Nigella Sativa (Black Cumin) Seed Oil (Skin Conditioning, Perfuming, Emollient)	Fungal Acne Trigger
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1		Aesculus Hippocastanum (Horse Chestnut) Extract	Good for sensitive skin
	A	Hippophae Rhamnoides Seed Oil (Skin Protecting)
1		Coconut Alkanes (Solvent, Emollient)	Bad for oily skin
1	B	Coco Caprylate/ Caprate (Skin Conditioning, Emollient)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1		Humulus Lupulus (Hops) Extract (Skin Conditioning, Perfuming, Emollient, Fragrance, Antimicrobial, Soothing, Tonic, Astringent)
1 2	A	Bisabolol	Promotes Wound Healing Brightening
1		Tocopherol	Good for dry skin Anti Aging

Simmondsia Chinensis (Jojoba) Seed Oil Extract

Function: Skin Conditioning, Emollient, Hair Conditioning, Abrasive

1. Definition Simmondsia Chinensis (Jojoba) Seed Oil Extract:

Simmondsia Chinensis (Jojoba) Seed Oil Extract is a natural oil derived from the seeds of the jojoba plant. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and hair care products.

2. Use:

Jojoba Seed Oil Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and lip balms due to its lightweight texture and non-greasy feel. Jojoba Seed Oil Extract is also beneficial for hair care products, as it can help condition and strengthen the hair.

3. Usage Simmondsia Chinensis (Jojoba) Seed Oil Extract:

When using products containing Jojoba Seed Oil Extract, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or used as an ingredient in DIY beauty recipes. Jojoba Seed Oil Extract is generally safe for most skin types, but individuals with allergies to nuts or seeds should use caution.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." 7th Edition.

- Dweck, A. C. (2003). "The Jojoba Story." Personal Care Magazine, 4(1), 1-4.

- Meier, L., & Sticher, O. (2004). "Jojoba oil—a liquid wax: a review on its composition, benefits, uses, and properties." Revista Brasileira de Farmacognosia, 14(1), 1-6.

Calophyllum Inophyllum Oil

Function:

1. Definition Calophyllum Inophyllum Oil:

Calophyllum Inophyllum Oil, also known as Tamanu Oil, is a botanical oil extracted from the nuts of the Calophyllum inophyllum tree. It is rich in fatty acids, antioxidants, and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Calophyllum Inophyllum Oil is commonly used in cosmetics for its moisturizing and healing properties. It is known to promote skin regeneration, reduce inflammation, and improve the overall appearance of the skin. It is often used in products for treating scars, stretch marks, acne, eczema, and other skin conditions.

3. Usage Calophyllum Inophyllum Oil:

When using Calophyllum Inophyllum Oil in cosmetics, it is important to perform a patch test before applying it to the skin, as some individuals may be sensitive to the oil. It can be used directly on the skin as a moisturizer or added to skincare products such as serums, creams, and lotions. It is recommended to use the oil sparingly, as a little goes a long way due to its rich and potent properties.

4. References:

- Kim, S. K., Karadeniz, F., & Kim, Y. T. (2013). Anti-inflammatory effect of Calophyllum inophyllum L. in RAW264.7 cells. Journal of Functional Foods, 5(4), 2197-2204.

- Nair, R., Kalariya, T., & Chanda, S. (2009). Antibacterial activity of some selected Indian medicinal flora. Turkish Journal of Biology, 33(2), 71-75.

- Léguillier, T., Lémus, C., Souza, C., Queiroz, V., Marcourt, L., Beniddir, M. A., ... & Espindola, L. (2015). In vitro antiplasmodial activity of Brazilian Cerrado plants used as traditional remedies. Journal of Ethnopharmacology, 173, 545-555.

Borago Officinalis (Borage) Seed Oil

Function: Skin Conditioning, Emollient

1. Definition Borago Officinalis (Borage) Seed Oil:

Borago Officinalis (Borage) Seed Oil is a natural oil extracted from the seeds of the borage plant. It is known for its high content of gamma-linolenic acid (GLA), an essential fatty acid that is beneficial for the skin.

2. Use:

Borage Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is known to help improve the appearance of dry, damaged, or aging skin. The oil is also believed to have anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products.

3. Usage Borago Officinalis (Borage) Seed Oil:

Borage Seed Oil can be used in a variety of cosmetic products, including moisturizers, serums, and facial oils. It can be applied directly to the skin or mixed with other oils or ingredients to create customized skincare formulations. It is important to perform a patch test before using Borage Seed Oil to ensure compatibility with your skin. As with any new ingredient, it is recommended to consult with a dermatologist or skincare professional before incorporating Borage Seed Oil into your routine.

4. References:

- Simopoulos, A. P. (1991). Omega-6 essential fatty acids: pathophysiology and roles in clinical medicine. The Journal of the American College of Nutrition, 10(5), 383-393.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Saeedi, M., Morteza-Semnani, K., Ghoreishi, M. R., & Akbarzadeh, M. (2013). The treatment of atopic dermatitis with licorice gel. Journal of Dermatological Treatment, 24(4), 260-264.

Salvia Hispanica (Chia) Oil

Function:

Helianthus Annuus (Sunflower) Seed Oil

Other name: Helianthus Annuus Seed oil; Sunflower Seed oil

Function:

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

Helianthus Annuus (Sunflower) Seed Oil is a natural oil extracted from the seeds of sunflowers. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Sunflower seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin barrier function, and promote a healthy complexion. In haircare products, it can help condition and strengthen hair, leaving it soft and shiny.

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

Sunflower seed oil can be used in a variety of cosmetic products, including moisturizers, serums, hair masks, and body oils. It is suitable for all skin types, including sensitive and acne-prone skin. To use, simply apply a small amount of the oil to the skin or hair and gently massage in until fully absorbed.

Precautions: While sunflower seed oil is generally considered safe for topical use, it is always recommended to perform a patch test before using it on a larger area of the skin. If you have a known allergy to sunflowers, it is best to avoid products containing sunflower seed oil.

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

Lactobacillus/Salix Alba Bark Ferment Filtrate

Function:

Nigella Sativa (Black Cumin) Seed Oil

Function: Skin Conditioning, Perfuming, Emollient

1. Definition Nigella Sativa (Black Cumin) Seed Oil:

Nigella Sativa (Black Cumin) Seed Oil is a natural oil extracted from the seeds of the Nigella Sativa plant, also known as black cumin or black seed. It has been used for centuries in traditional medicine and is known for its potent anti-inflammatory, antioxidant, and antibacterial properties.

2. Use:

Black Cumin Seed Oil is commonly used in cosmetics for its ability to nourish and moisturize the skin. It is rich in essential fatty acids, vitamins, and minerals that help improve skin texture, reduce inflammation, and promote healthy skin cell regeneration. It is often included in skincare products such as serums, moisturizers, and facial oils.

3. Usage Nigella Sativa (Black Cumin) Seed Oil:

When using Black Cumin Seed Oil in cosmetics, it is important to perform a patch test before applying it directly to the skin to check for any allergic reactions. It is recommended to dilute the oil with a carrier oil before applying it topically, as it is highly concentrated. Avoid using it near the eyes and mucous membranes, and discontinue use if any irritation occurs.

4. References:

- Cheikh-Rouhou, S., Besbes, S., Hentati, B., Blecker, C., & Deroanne, C. (2007). Nigella Sativa L.: Chemical composition and physicochemical characteristics of lipid fraction. Food Chemistry, 101(2), 673-681.

- Ahmad, A., Husain, A., Mujeeb, M., Khan, S. A., Najmi, A. K., Siddique, N. A., ... & Anwar, F. (2013). A review on therapeutic potential of Nigella Sativa: A miracle herb. Asian Pacific Journal of Tropical Biomedicine, 3(5), 337-352.

- Tavakkoli, A., Mahdian, V., Razavi, B. M., & Hosseinzadeh, H. (2017). Review on clinical trials of black seed (Nigella Sativa) and its active constituent, thymoquinone. Journal of Pharmacopuncture, 20(3), 179-193.

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Aesculus Hippocastanum (Horse Chestnut) Extract

Function:

1. Definition Aesculus Hippocastanum (Horse Chestnut) Extract:

Aesculus Hippocastanum (Horse Chestnut) Extract is a botanical ingredient derived from the seeds of the Horse Chestnut tree. It is known for its anti-inflammatory, antioxidant, and astringent properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Horse Chestnut Extract is commonly used in cosmetic formulations for its ability to improve the appearance of skin by reducing redness, swelling, and inflammation. It is also known to help strengthen blood vessels, which can be beneficial for reducing the appearance of dark circles and puffiness around the eyes.

3. Usage Aesculus Hippocastanum (Horse Chestnut) Extract:

Horse Chestnut Extract is typically found in creams, lotions, serums, and eye treatments. It can be applied directly to the skin or mixed with other ingredients to create a customized skincare product. When using products containing Horse Chestnut Extract, it is important to follow the manufacturer's instructions for application and frequency to achieve the desired results.

4. References:

- Kim, J. E., Lee, S. H., Lee, S. Y., Lee, S. J., & Chung, B. C. (2013). Anti-inflammatory mechanism of Aesculus hippocastanum L. bark in HMGB1-induced inflammatory responses. Journal of Ethnopharmacology, 148(3), 937-945.

- Saeed, S. A., Simjee, S. U., & Shamim, G. (2015). Anti-inflammatory activity of Aesculus hippocastanum L. in experimental animals. African Journal of Pharmacy and Pharmacology, 9(5), 120-126.

- Kwon, Y. S., Kim, K. M., & Jang, H. D. (2015). Horse chestnut (Aesculus hippocastanum) seed extract affects viability, apoptosis, necrosis, and oxidative stress in HepG2 human hepatocellular carcinoma cells. Nutrition Research and Practice, 9(6), 625-632.

Hippophae Rhamnoides Seed Oil

Function: Skin Protecting

1. Definition Hippophae Rhamnoides Seed Oil:

Hippophae Rhamnoides Seed Oil, also known as Sea Buckthorn Seed Oil, is a natural oil extracted from the seeds of the sea buckthorn plant. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Hippophae Rhamnoides Seed Oil is commonly used in cosmetics for its nourishing and moisturizing properties. It helps to improve skin hydration, elasticity, and firmness. The oil is also known for its anti-inflammatory and antioxidant properties, which can help protect the skin from environmental damage and reduce signs of aging.

3. Usage Hippophae Rhamnoides Seed Oil:

Hippophae Rhamnoides Seed Oil can be used in various skincare products, such as serums, moisturizers, and facial oils. It is suitable for all skin types, including sensitive and acne-prone skin. The oil can be applied directly to the skin or mixed with other skincare ingredients to enhance its benefits. It is recommended to perform a patch test before using the oil to check for any allergic reactions.

4. References:

- Kim, J. H., Lee, H. J., Jeong, S. J., Lee, H. J., Kim, B. W., Park, J. H., ... & Kim, H. R. (2017). Anti-inflammatory mechanism of Hippophae rhamnoides L. in a co-culture system of 3T3-L1 adipocytes and RAW 264.7 macrophages. Journal of Ethnopharmacology, 202, 10-18.

- Yang, B., & Kallio, H. (2002). Composition and physiological effects of sea buckthorn (Hippophae) lipids. Trends in Food Science & Technology, 13(5), 160-167.

- Zheng, J., Ding, C., Wang, L., Li, G., Shi, J., Li, H., ... & Liu, L. (2017). Hippophae rhamnoides L. in the treatment of asthmatic mice: Effect on the NF-κB pathway. Journal of Ethnopharmacology, 203, 30-39.

Coconut Alkanes

Function: Solvent, Emollient

1. Definition Coconut Alkanes:

Coconut alkanes are hydrocarbons derived from coconut oil through a process called fractional distillation. They are commonly used in cosmetics as a natural alternative to silicones for their emollient and conditioning properties.

2. Use:

Coconut alkanes are used in a wide range of cosmetic products such as moisturizers, hair care products, and makeup to provide a silky smooth texture and enhance the spreadability of the product. They also help to improve the skin's barrier function and prevent moisture loss, making them ideal for dry and sensitive skin types.

3. Usage Coconut Alkanes:

When using products containing coconut alkanes, it is important to patch test first to check for any allergic reactions or sensitivities. It is recommended to follow the instructions provided on the product packaging and avoid applying them to broken or irritated skin. Coconut alkanes are generally considered safe for use in cosmetics, but individuals with coconut allergies should exercise caution.

4. References:

- S. M. G. C. L. E. Silva, M. S. B. Oliveira, C. S. P. Silva, L. M. S. L. A. Silva, J. A. D. S. Sousa, A. C. S. C. Teixeira, & M. S. S. G. S. Costa. (2015). Coconut oil: What do we really know about it so far? Food Quality and Safety, 1(3), 107-115.

- Rele, A. S., & Mohile, R. B. (2003). Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage. Journal of Cosmetic Science, 54(2), 175-192.

- Korać, R. R., & Khambholja, K. M. (2011). Potential of herbs in skin protection from ultraviolet radiation. Pharmacognosy Reviews, 5(10), 164-173.

Coco Caprylate/ Caprate

Function: Skin Conditioning, Emollient

1. Definition Coco Caprylate/ Caprate:

Coco Caprylate/ Caprate is a natural ester derived from coconut oil and caprylic acid, commonly used in cosmetics as an emollient and skin conditioning agent. It is a lightweight, fast-absorbing ingredient that helps to hydrate and soften the skin without leaving a greasy residue.

2. Use:

Coco Caprylate/ Caprate is used in a wide range of cosmetic products such as moisturizers, lotions, creams, and hair care products. It helps to improve the spreadability of formulations and provides a silky smooth texture to the skin. Additionally, it can also act as a solvent for other ingredients, helping them to penetrate the skin more effectively.

3. Usage Coco Caprylate/ Caprate:

When using products containing Coco Caprylate/ Caprate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Coco-Caprylate/Caprate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/coco-caprylatecaprate

- "Coco-Caprylate" by Truth In Aging, https://www.truthinaging.com/ingredients/coco-caprylate

- "Coco-Caprylate" by Skin Deep, https://www.ewg.org/skindeep/ingredients/706751-COCO-CAPRYLATE/

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Humulus Lupulus (Hops) Extract

Function: Skin Conditioning, Perfuming, Emollient, Fragrance, Antimicrobial, Soothing, Tonic, Astringent

1. Definition Humulus Lupulus (Hops) Extract:

Humulus Lupulus (Hops) Extract is derived from the flowers of the hop plant and is commonly used in cosmetics for its skin-soothing, antioxidant, and anti-inflammatory properties.

2. Use:

Hops extract is often included in skincare products for its ability to calm and condition the skin, making it suitable for sensitive or irritated skin types. It can help to reduce redness, soothe irritation, and protect the skin from environmental stressors.

3. Usage Humulus Lupulus (Hops) Extract:

Hops extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 2% and can be applied directly to the skin as part of a daily skincare routine. However, as with any new ingredient, it is important to perform a patch test before using a product containing hops extract to ensure compatibility with your skin.

4. References:

- Hops Extract: Benefits for Skin and Hair. (n.d.). Retrieved from https://www.healthline.com/health/hops-extract

- Humulus Lupulus (Hops) Extract. (n.d.). Retrieved from https://incidecoder.com/ingredients/humulus-lupulus-extract

- Hops Extract. (n.d.). Retrieved from https://www.paulaschoice.com/ingredient-dictionary/plant-extracts/hops-extract

Bisabolol

Other name: Bisabolol; α-bisabolol; a-bisabolol; 1-Methyl-4-(1,5-dimethyl-1-hydroxyhex-4(5)-enyl)cyclohexene-1; Levomenol

Function:

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.