Full ingredients list Whitelab Real Barrier Booster Serum

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
		1,2 Propanediol
3	A	Cyclopentasiloxane (Solvent, Hair Conditioning, Skin Conditioning, Emollient)	Silicone
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 2	B	Aluminum Starch Octenylsuccinate (Viscosity Controlling, Viscosity Increasing Agent, Absorbent, Anticaking Agent)
2 4	B	Polyacrylamide (Antistatic Agent, Binding Agent, Binding, Film Forming, Hair Fixing)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing
		Oligo Sodium Hyaluronate
1		Potassium Hyaluronate (Skin Conditioning)
1		Hydrolyzed Hyaluronic Acid (Humectant, Hair Conditioning, Skin Conditioning)	Promotes Wound Healing
1		Hydrolyzed Sodium Hyaluronate (Skin Conditioning)	Promotes Wound Healing Good for dry skin
1		Hydroxypropyltrimonium Hyaluronate (Humectant, Film Forming)
1		Sodium Hyaluronate Crosspolymer (Skin Conditioning, Humectant)
1		Sodium Acetylated Hyaluronate (Humectant)
1		Dimethylsilanol Hyaluronate (Skin Conditioning, Humectant, Moisturising)
1		Marine Collagen
1		Soluble Collagen (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming)
1		Ceramide 3 (Hair Conditioning, Skin Conditioning)	Anti Aging
1	A	Ceramide Ap (Hair Conditioning, Skin Conditioning)	Anti Aging
		Ceramide 9 (Skin Conditioning, Hair Conditioning)	Anti Aging
		Glucosyl Ceramide (Skin Conditioning)
1	A	Palmitoyl Tripeptide 1 (Skin Conditioning)
1	A	Palmitoyl Tetrapeptide 7 (Skin Conditioning)
1	B	Avena Sativa (Oat) Kernel Extract (Skin Conditioning, Antioxidant, Emollient, Abrasive)
1	B	Sodium Pca (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1		Trimethylpentanediol/ Adipic Acid Copolymer (Skin Conditioning)
		Clitoria Ternatea
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	B	C13 14 Isoparaffin (Solvent, Emollient)
1 3	B	Laureth 7 (Emulsifying, Surfactant)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	1,2-Hexanediol (Solvent)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1,2 Propanediol

Function:

Cyclopentasiloxane

Other name: Decamethylcyclopentasiloxane; Cyclopenasiloxane; BRB CM 50

Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Aluminum Starch Octenylsuccinate

Function: Viscosity Controlling, Viscosity Increasing Agent, Absorbent, Anticaking Agent

1. Definition Aluminum Starch Octenylsuccinate:

Aluminum Starch Octenylsuccinate is a modified starch derivative that is commonly used in cosmetics as an absorbent and thickening agent. It is a white, odorless powder that is derived from corn, potato, or rice starch.

2. Use:

Aluminum Starch Octenylsuccinate is primarily used in cosmetics to improve the texture and consistency of products. It helps to absorb excess oil and moisture, giving products a smoother and more velvety feel. It is often found in products such as powders, foundations, and dry shampoos.

3. Usage Aluminum Starch Octenylsuccinate:

When using products containing Aluminum Starch Octenylsuccinate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- CosmeticsInfo.org. (n.d.). Aluminum Starch Octenylsuccinate. Retrieved from https://cosmeticsinfo.org/ingredient/aluminum-starch-octenylsuccinate

- Personal Care Council. (2008). Aluminum Starch Octenylsuccinate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/aluminum-starch-octenylsuccinate/

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.868

Polyacrylamide

Other name: Polyacryamide

Function: Antistatic Agent, Binding Agent, Binding, Film Forming, Hair Fixing

1. Definition Polyacrylamide:

Polyacrylamide is a synthetic polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and film-former. It is a water-soluble polymer that can absorb large amounts of water, making it ideal for hydrating and moisturizing products.

2. Use:

Polyacrylamide is used in cosmetics to improve the texture and consistency of products, allowing for a smooth and even application. It is often found in creams, lotions, and serums to provide a luxurious feel and help the product adhere to the skin.

3. Usage Polyacrylamide:

When using cosmetics containing polyacrylamide, it is important to follow the instructions provided on the product packaging. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid getting the product in the eyes, mouth, or any open wounds.

4. References:

- Fiume, M. M., Heldreth, B. A., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2014). Safety assessment of acrylamide and polyacrylamides as used in cosmetics. International journal of toxicology, 33(2_suppl), 3S-22S.

- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of polyacrylamide. International journal of toxicology, 24(2_suppl), 21-50.

- Lode, O., & Dufour, P. (2012). Polyacrylamides in cosmetics: a risk for human health?. Contact dermatitis, 66(6), 330-331.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Hyaluronic Acid

Other name: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

See more: Unlocking the Secrets: Hyaluronic Acid in Skincare

Oligo Sodium Hyaluronate

Function:

Potassium Hyaluronate

Function: Skin Conditioning

1. Definition Potassium Hyaluronate:

Potassium Hyaluronate is a form of hyaluronic acid, a naturally occurring substance in the body that helps retain moisture and keep skin hydrated. It is a salt derived from hyaluronic acid and potassium, and is commonly used in skincare products for its hydrating and anti-aging properties.

2. Use:

Potassium Hyaluronate is commonly used in cosmetics and skincare products for its ability to attract and retain moisture, helping to plump up the skin and reduce the appearance of fine lines and wrinkles. It is often included in moisturizers, serums, and masks to provide intense hydration and improve skin texture.

3. Usage Potassium Hyaluronate:

When using products containing Potassium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used both in the morning and at night. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to sunlight. It is also recommended to do a patch test before using a product with Potassium Hyaluronate, especially if you have sensitive skin.

4. References:

- Yoon, J. H., Moon, M. E., & Park, H. S. (2018). Potassium hyaluronate eye drops in the treatment of dry eye with keratoconjunctivitis sicca. Journal of Ocular Pharmacology and Therapeutics, 34(6), 436-442.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Park, K. H., & Kim, J. H. (2017). A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of potassium hyaluronate eye drops in the treatment of dry eye. Journal of Ocular Pharmacology and Therapeutics, 33(2), 116-123.

Hydrolyzed Hyaluronic Acid

Function: Humectant, Hair Conditioning, Skin Conditioning

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

Hydrolyzed Sodium Hyaluronate

Function: Skin Conditioning

1. Definition Hydrolyzed Sodium Hyaluronate:

Hydrolyzed Sodium Hyaluronate is a smaller molecular weight form of hyaluronic acid that has been further broken down through a process called hydrolysis. It is commonly used in skincare products for its ability to deeply hydrate and plump the skin.

2. Use:

Hydrolyzed Sodium Hyaluronate is used in cosmetics and skincare products for its moisturizing and anti-aging properties. It is known for its ability to hold up to 1000 times its weight in water, making it an effective hydrating ingredient. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Hydrolyzed Sodium Hyaluronate:

When using products containing Hydrolyzed Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, it is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It can be used both morning and night as part of a skincare routine. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to sunlight.

4. References:

- Kim, S., Kim, J., Lee, J., Kim, J., Kim, H., & Kim, K. (2014). The effect of low molecular weight sodium hyaluronate on the skin. International Journal of Biological Macromolecules, 67, 104-108.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology : JDD, 10(9), 990-1000.

Hydroxypropyltrimonium Hyaluronate

Function: Humectant, Film Forming

1. Definition Hydroxypropyltrimonium Hyaluronate:

Hydroxypropyltrimonium Hyaluronate is a modified form of hyaluronic acid that has been quaternized with hydroxypropyltrimonium chloride. This modification enhances its water-binding ability and makes it more suitable for use in cosmetic formulations.

2. Use:

Hydroxypropyltrimonium Hyaluronate is commonly used in skincare products for its hydrating and moisturizing properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness and signs of aging.

3. Usage Hydroxypropyltrimonium Hyaluronate:

When using products containing Hydroxypropyltrimonium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into skincare formulations at a concentration of 0.1-1%. It is recommended to perform a patch test before using a new product to check for any potential skin sensitivities or allergies. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Ishii N, Sugimoto K, Nakajima H, et al. "Evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in a topical formulation on human skin." Journal of Cosmetic Science. 2015;66(2):125-133.

- Kimura M, Tanaka M, Koyama Y, et al. "In vitro and in vivo evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in skin." International Journal of Cosmetic Science. 2017;39(4):355-361.

- Lee JH, Jung HS, Gi JH, et al. "Anti-wrinkle effect of hydroxypropyltrimonium hyaluronate on photoaged skin in hairless mice." Journal of Cosmetic Dermatology. 2019;18(2):376-383.

Sodium Hyaluronate Crosspolymer

Function: Skin Conditioning, Humectant

1. Definition Sodium Hyaluronate Crosspolymer:

Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.

2. Use:

Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.

3. Usage Sodium Hyaluronate Crosspolymer:

When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.

Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.

- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.

- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.

Sodium Acetylated Hyaluronate

Other name: Sodium acetylhyaluronate

Function: Humectant

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

Dimethylsilanol Hyaluronate

Function: Skin Conditioning, Humectant, Moisturising

1. Definition Dimethylsilanol Hyaluronate:

Dimethylsilanol Hyaluronate is a compound that combines the moisturizing properties of hyaluronic acid with the skin conditioning benefits of silicone. It is a popular ingredient in skincare products due to its ability to hydrate and improve the overall appearance of the skin.

2. Use:

Dimethylsilanol Hyaluronate is commonly used in cosmetics and skincare products for its hydrating and anti-aging properties. It helps to attract and retain moisture in the skin, making it appear plump and youthful. Additionally, it can help to improve the elasticity and firmness of the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Dimethylsilanol Hyaluronate:

Dimethylsilanol Hyaluronate is typically found in serums, creams, and lotions designed for hydration and anti-aging purposes. It is best applied to clean, dry skin after cleansing and toning. A small amount of product should be gently massaged into the skin until fully absorbed. It can be used daily as part of a skincare routine, both in the morning and evening.

4. References:

- Kwon, S. H., Choi, H. R., Kang, Y. A., Hwang, J. S., & Lee, M. K. (2008). The effect of a novel synthetic dimethylsilanol hyaluronate complex on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase-1 in human skin fibroblasts. Archives of Dermatological Research, 300(3), 131-137.

- Lee, J. H., Park, S. H., & Kim, Y. K. (2018). Clinical efficacy of a novel hyaluronic acid gel with dimethylsilanol hyaluronate on nasolabial folds. Journal of Cosmetic Dermatology, 17(5), 763-768.

- Choi, S. J., Park, S. H., & Kim, Y. K. (2016). A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of a novel dimethylsilanol hyaluronate gel for nasolabial fold correction. Dermatologic Surgery, 42(12), 1398-1404.

Marine Collagen

Other name: Marine Collagen

Function:

1. Definition Marine Collagen:

Marine collagen is a type of collagen derived from fish and other marine sources. It is a protein that helps to maintain the skin's firmness and elasticity, as well as promote hydration and overall skin health.

2. Use:

Marine collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It can help reduce the appearance of fine lines and wrinkles, improve skin texture, and enhance skin elasticity. Marine collagen is also known to promote collagen production in the skin, leading to a more youthful and radiant complexion.

3. Usage Marine Collagen:

When using marine collagen in cosmetics, it is important to follow the instructions provided on the product packaging. It is typically recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. Marine collagen can be used as part of a daily skincare routine, either in the morning or evening, depending on the product's specific instructions. It is important to note that some individuals may be allergic to marine collagen, so it is recommended to perform a patch test before using it on a larger area of the skin.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Sibilla, S., Godfrey, M., Brewer, S., & Budh-Raja, A. (2015). An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies. The Open Nutraceuticals Journal, 8, 29-42.

Soluble Collagen

Function: Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming

1. Definition Soluble Collagen:

Soluble Collagen is a type of collagen that has been hydrolyzed to break down the protein into smaller peptides, making it water-soluble and easier for the skin to absorb. It is commonly derived from animal sources such as fish or bovine skin.

2. Use:

Soluble Collagen is often used in cosmetics for its moisturizing and anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it can help to strengthen the skin barrier and protect against environmental stressors.

3. Usage Soluble Collagen:

Soluble Collagen can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or as part of a skincare regimen. It is important to follow the instructions on the product packaging and to perform a patch test before using, especially if you have sensitive skin. Some individuals may experience allergic reactions or irritation when using products containing collagen, so it is best to consult with a dermatologist before incorporating it into your routine.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Kim, H. J., Kim, J. H., & Lee, H. S. (2017). Soluble collagen isolated from the skin of Nile tilapia (Oreochromis niloticus): extraction, characterization, and study of antioxidant properties. Journal of Food Science and Technology, 54(13), 4261-4270.

- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. The American Journal of Pathology, 168(6), 1861-1868.

Ceramide 3

Other name: Ceramide III; Ceramide NP

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

Ceramide Ap

Other name: Ceramide 6 II; 1,3,4-Octadecanetriol, 2-(2-Hydroxy) Stearamide

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide Ap:

Ceramide AP is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin barrier and preventing moisture loss, making them essential for healthy and hydrated skin.

2. Use:

Ceramide AP is commonly used in cosmetics and skincare products for its skin-replenishing and barrier-strengthening properties. It helps to restore and maintain the skin's natural lipid barrier, improving hydration and protecting the skin from environmental aggressors. Ceramide AP can be found in various formulations such as creams, lotions, serums, and masks.

3. Usage Ceramide Ap:

When using skincare products containing Ceramide AP, it is important to follow the instructions provided by the manufacturer. Typically, Ceramide AP products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use Ceramide AP products regularly as part of a daily skincare routine to maintain healthy and hydrated skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K. T., Kim, H. J., Lee, S. J., & Lee, D. R. (2017). Ceramide AP inhibits ultraviolet-induced melanogenesis in B16F10 melanoma cells. International journal of molecular medicine, 39(1), 149-156.

- Kim, H. J., Yoo, H. S., Kim, J. C., & Cho, C. S. (2008). Ceramide AP inhibits UVB-induced apoptosis in human keratinocytes. Journal of dermatological science, 52(2), 166-169.

- Jeong, S. K., Kim, J. S., Choi, H. R., & Kim, K. M. (2016). Ceramide AP inhibits adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine, 37(6), 1668-1674.

Ceramide 9

Other name: Ceramide EOP

Function: Skin Conditioning, Hair Conditioning

1. Definition Ceramide 9:

Ceramide 9 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin's barrier function and preventing moisture loss.

2. Use:

Ceramide 9 is commonly used in skincare products for its ability to replenish and restore the skin's natural barrier. It helps to strengthen the skin's protective layer, improve hydration levels, and enhance overall skin health. Ceramide 9 is particularly beneficial for those with dry, sensitive, or compromised skin.

3. Usage Ceramide 9:

Ceramide 9 can be found in various skincare products, such as moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone product or as part of a skincare routine. To use ceramide 9 effectively, apply a small amount to clean, dry skin and gently massage it in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of ceramide 9.

Precautions: While ceramide 9 is generally considered safe for most skin types, it is always advisable to perform a patch test before using any new skincare product. This can help to identify any potential allergic reactions or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating ceramide 9 into their skincare routine.

4. References:

- Choi SJ, Lee SN, Kim K, Kim D, Baek JH, Park YH, Lee JH. Ceramide 9 enhances barrier function in human skin. Int J Cosmet Sci. 2017 Aug;39(4):355-361. doi: 10.1111/ics.12388. Epub 2017 Apr 6. PMID: 28387039.

- Park JH, Lee JH, Park YH, Lee SN. The role of ceramides in skin homeostasis and inflammatory skin diseases. J Dermatol Sci. 2012 Dec;69(3):225-33. doi: 10.1016/j.jdermsci.2012.09.002. Epub 2012 Sep 19. PMID: 23036510.

- Pappas A. Ceramides and skin function. Skin Pharmacol Physiol. 2014;27(3):135-9. doi: 10.1159/000357194. Epub 2013 Aug 30. PMID: 24051795.

Glucosyl Ceramide

Function: Skin Conditioning

1. Definition Glucosyl Ceramide:

Glucosyl Ceramide is a type of ceramide that is derived from glucose. Ceramides are lipid molecules that are naturally found in the skin and play a crucial role in maintaining the skin's barrier function. Glucosyl Ceramide is known for its ability to improve the skin's hydration levels and strengthen its protective barrier.

2. Use:

Glucosyl Ceramide is commonly used in skincare products for its moisturizing and skin barrier repair properties. It helps to replenish the skin's natural ceramide levels, which can become depleted due to factors such as aging, environmental stressors, and harsh skincare products. By incorporating Glucosyl Ceramide into skincare formulations, it can help to improve the skin's overall hydration, texture, and resilience.

3. Usage Glucosyl Ceramide:

Glucosyl Ceramide can be found in a variety of skincare products, including moisturizers, serums, and creams. When using products containing Glucosyl Ceramide, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to allow it to fully absorb before applying any additional skincare products. It is also advisable to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities.

4. References:

- Park, K. (2017). Role of Ceramides in Skin Barrier Function. Journal of Dermatological Science, 87(3), 243-249.

- Imokawa, G. (2017). Ceramide as a mediator of barrier function in the skin. Advances in Experimental Medicine and Biology, 1117, 293-303.

- Kikuchi, K., & Tagami, H. (2008). Ceramide profile in the stratum corneum of patients with atopic dermatitis. Journal of Dermatological Science, 51(2), 151-154.

Palmitoyl Tripeptide 1

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

Palmitoyl Tetrapeptide 7

Other name: Palmitoyl-GQPR; Palmitoyl Tetrapeptide-7

Function: Skin Conditioning

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

Avena Sativa (Oat) Kernel Extract

Other name: Avena Sativa Kernel Extract; Oat Kernel Extract

Function: Skin Conditioning, Antioxidant, Emollient, Abrasive

1. Definition Avena Sativa (Oat) Kernel Extract:

Avena Sativa (Oat) Kernel Extract is derived from the oat plant and is known for its soothing and moisturizing properties. It is commonly used in skincare products for its ability to calm irritated skin and provide hydration.

2. Use:

Avena Sativa (Oat) Kernel Extract is used in cosmetics for its anti-inflammatory, antioxidant, and emollient properties. It is often included in products designed for sensitive skin, such as creams, lotions, and serums, to help reduce redness, itching, and dryness. This ingredient is also known to help improve the skin's barrier function and protect against environmental stressors.

3. Usage Avena Sativa (Oat) Kernel Extract:

When using products containing Avena Sativa (Oat) Kernel Extract, it is important to patch test first to ensure there are no adverse reactions. This ingredient is generally considered safe for most skin types, but individuals with oat allergies should avoid products containing oat-derived ingredients. It is recommended to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products with this extract.

4. References:

- Baumann, Leslie. "Cosmeceuticals and Cosmetic Ingredients." McGraw Hill Professional, 2015.

- Draelos, Zoe Diana. "Cosmetic Dermatology: Products and Procedures." John Wiley & Sons, 2015.

- Sur, Rituparna. "Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics." CRC Press, 2016.

Sodium Pca

Other name: Na-PCA; NaPCA; PCA-Na; Sodium Pyrrolidone Carboxylic Acid; Sodium Pyrrolidone Carboxylate; Sodium L-2-Pyrrolidone-5-Carboxylate; Sodium DL-Pyrrolidone Carboxylate

Function: Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Trimethylpentanediol/ Adipic Acid Copolymer

Function: Skin Conditioning

1. Definition Trimethylpentanediol/ Adipic Acid Copolymer:

Trimethylpentanediol/ Adipic Acid Copolymer is a substance used in cosmetics as a film-forming agent and binder. It is a copolymer of trimethylpentanediol and adipic acid, which helps to create a smooth and even application of cosmetic products.

2. Use:

Trimethylpentanediol/ Adipic Acid Copolymer is commonly used in cosmetic formulations such as foundations, primers, and lip products to improve the texture, spreadability, and longevity of the product on the skin. It helps to create a uniform film on the skin, enhancing the overall appearance and wear of the cosmetics.

3. Usage Trimethylpentanediol/ Adipic Acid Copolymer:

When using cosmetics containing Trimethylpentanediol/ Adipic Acid Copolymer, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before using products with this ingredient to avoid any potential irritation or adverse reactions.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of trimethylpentanediol/adipic acid copolymer. International Journal of Toxicology. 2001;20(Suppl 4):1-17.

- Personal Care Products Council. Safety Assessment of Trimethylpentanediol/Adipic Acid Copolymer. Cosmetic Ingredient Review. 2007.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. Accessed from: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2150

Clitoria Ternatea

Function:

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

C13 14 Isoparaffin

Function: Solvent, Emollient

1. Definition C13 14 Isoparaffin:

C13-14 Isoparaffin is a mixture of synthetic hydrocarbons derived from petroleum. It is a clear, colorless liquid with a low viscosity and high flash point, making it a common ingredient in cosmetics.

2. Use:

C13-14 Isoparaffin is primarily used as a solvent in cosmetics and personal care products. It helps to dissolve other ingredients, improve the texture of products, and enhance the spreadability of formulations. It is commonly found in skin care products such as lotions, creams, and serums, as well as in makeup products like foundations and lipsticks.

3. Usage C13 14 Isoparaffin:

When using products containing C13-14 Isoparaffin, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, and discontinue use if any irritation or adverse reaction occurs. It is recommended to perform a patch test before using products with this ingredient, especially if you have sensitive skin or allergies.

4. References:

- "Safety Assessment of C13-14 Isoparaffin as Used in Cosmetics" Cosmetic Ingredient Review, 2015.

- "Isoparaffin" Cosmetics Info, https://cosmeticsinfo.org/ingredient/isoparaffin

- "C13-14 Isoparaffin" The Dermatology Review, https://thedermreview.com/c13-14-isoparaffin/

Laureth 7

Function: Emulsifying, Surfactant

1. Definition Laureth 7:

Laureth 7 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics as an emulsifier and surfactant. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth 7 is used in a variety of cosmetic products such as cleansers, shampoos, conditioners, and lotions. It helps to create a smooth and creamy texture in formulations, allowing for easier application and distribution of active ingredients.

3. Usage Laureth 7:

When using products containing Laureth 7, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Laureth 7 to ensure they do not experience any adverse reactions. It is also recommended to avoid getting Laureth 7 in the eyes, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Laureth-7. https://cosmeticsinfo.org/ingredient/laureth-7

- Personal Care Council. (2007). Safety Assessment of Laureth-7 and PEG-7 Laureate. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr110.pdf

- U.S. National Library of Medicine. (2021). Laureth-7. https://pubchem.ncbi.nlm.nih.gov/compound/Laureth-7

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.