Full ingredients list ZO Skin Health Growth Factor Eye Serum

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1		Bellis Perennis (Daisy) Flower Extract (Skin Conditioning)
3	A	Dimethicone Peg 10/ 15 Crosspolymer (Film Forming, Opacifying)
3	A	Peg/ Ppg 18/ 18 Dimethicone (Emulsifying)
1	A	Lupinus Albus Seed Oil (Skin Conditioning)	Fungal Acne Trigger
1	A	Triticum Vulgare (Wheat) Germ Oil (Skin Conditioning, Emollient)	Bad for oily skin Fungal Acne Trigger
2 4	B	Peg 35 Castor Oil (Surfactant, Emulsifying)	Fungal Acne Trigger
1		Hieracium Pilosella Extract (Skin Conditioning, Masking)
1		Scutellaria Baicalensis Root Extract (Humectant, Astringent, Soothing)
		Cordyceps Militaris Mycelium Extract (Skin Conditioning)
4	A	Glycyrrhiza Uralensis (Licorice) Root Extract (Skin Conditioning)	Acne fighting Brightening
		Angelica Polymorpha Sinensis Root Extract (Skin Conditioning)
		Buddleja Davidii Meristem Cell Culture (Skin Conditioning)
		Lactobacillus/Panax Ginseng Root Ferment Filtrate
1		Sodium Chloride (Masking, Viscosity Controlling, Bulking Agent)
1	A	Dimethicone Crosspolymer (Viscosity Controlling, Emulsion Stabilising, Hair Fixing, Suspending Agent - Nonsurfactant, Viscosity Increasingagent - Nonaqueous)
1		Lactobacillus Ferment (Skin Conditioning)
1	A	Phospholipids (Skin Conditioning)
1	A	Sodium Citrate (Masking, pH adjusting agent, pH adjusting agent, Chelating)
1	A	Sodium Tocopheryl Phosphate (Skin Conditioning, Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Antioxidant, Reducing)
1 2	A	Hydrolyzed Sericin (Skin Conditioning, Hair Conditioning)
1		Beeswax (Emulsifying, Surfactant)
1	A	Dimethicone/ Vinyl Dimethicone Crosspolymer (Viscosity Controlling)
1		Sodium Acetylated Hyaluronate (Humectant)
1		Panthenyl Triacetate (Antistatic Agent, Hair Conditioning)
1	B	Acetyl Tyrosine (Skin Conditioning, Tanning)
1		Ethyl Linoleate (Skin Conditioning, Perfuming, Emollient, Fragrance)	Fungal Acne Trigger
1	A	1,2-Hexanediol (Solvent)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1	A	Proline (Fragrance, Hair Conditioning, Skin Conditioning)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1		Hydrolyzed Vegetable Protein (Skin Conditioning, Antistatic Agent, Hair Conditioning)
1	A	Oleyl Alcohol (Solvent, Skin Conditioning, Emollient, Fragrance, Viscosity Controlling, Emulsifying, Opacifying, Viscosity Increasingagent - Nonaqueous)	Bad for oily skin
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
1	B	Silica Silylate (Skin Conditioning, Emollient, Viscosity Controlling, Emulsion Stabilising, Antifoaming Agent, Bulking Agent, Anticaking Agent, Suspending Agent -Nonsurfactant)
1	A	Beta Glucan (Skin Conditioning, Bulking Agent)	Good for dry skin
1		Tocopherol	Good for dry skin Anti Aging
4		Disodium Acetyl Glucosamine Phosphate
1		Adenosine Triphosphate (Skin Conditioning)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1 6		Peg 12 Glyceryl Laurate (Emulsifying)
1		Acetyl Tetrapeptide 5 (Humectant)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1	A	Pvp (Viscosity Controlling, Antistatic Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Hair Fixing, Suspending Agent - Nonsurfactant)
1 3	A	Sodium Benzoate (Masking, Fragrance, Preservative, Anticorrosive)
1	A	Sodium Dehydroacetate (Preservative)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
2	A	Potassium Sorbate (Fragrance, Preservative)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Bellis Perennis (Daisy) Flower Extract

Function: Skin Conditioning

1. Definition Bellis Perennis (Daisy) Flower Extract:

Bellis Perennis (Daisy) Flower Extract is an extract derived from the common daisy flower, known for its soothing and calming properties. It is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Bellis Perennis (Daisy) Flower Extract is often included in skincare formulations to help reduce redness, irritation, and inflammation. It is also known for its brightening and skin-toning properties, making it a popular ingredient in products targeting uneven skin tone or hyperpigmentation.

3. Usage Bellis Perennis (Daisy) Flower Extract:

Bellis Perennis (Daisy) Flower Extract is typically found in creams, serums, lotions, and masks. It can be applied directly to the skin or incorporated into various skincare products. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M., Kim, S., & Lee, H. (2015). Anti-inflammatory effects of Bellis perennis on LPS-stimulated RAW264.7 cells. Immunopharmacology and Immunotoxicology, 37(3), 248-253.

- Kim, S., Kim, M., & Lee, H. (2016). Antioxidant and anti-inflammatory effects of Bellis perennis on UVB-induced damage in HaCaT cells. Journal of Cosmetic Dermatology, 15(4), 420-426.

- Park, J., Yoo, J., & Lee, H. (2018). Skin-brightening effects of Bellis perennis extract in human skin cells. Journal of Cosmetic Science, 69(1), 39-45.

Dimethicone Peg 10/ 15 Crosspolymer

Function: Film Forming, Opacifying

1. Definition Dimethicone Peg 10/ 15 Crosspolymer:

Dimethicone Peg 10/15 Crosspolymer is a type of silicone-based polymer that is commonly used in cosmetic formulations as a thickening agent, emulsifier, and skin conditioning agent.

2. Use:

Dimethicone Peg 10/15 Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and makeup products. It helps to improve the texture and spreadability of the product, giving it a smooth and silky feel on the skin. Additionally, it can also act as a barrier on the skin, helping to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone Peg 10/ 15 Crosspolymer:

When using products containing Dimethicone Peg 10/15 Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient to ensure compatibility with your skin.

4. References:

- "Dimethicone Peg-10/15 Crosspolymer" CosmeticsInfo.org, https://www.cosmeticsinfo.org/ingredient/dimethicone-peg-1015-crosspolymer

- "Dimethicone Peg-10/15 Crosspolymer" The Derm Review, https://thedermreview.com/dimethicone-peg-1015-crosspolymer/

- "Dimethicone Peg-10/15 Crosspolymer" Truth In Aging, https://www.truthinaging.com/ingredients/dimethicone-peg-1015-crosspolymer

Peg/ Ppg 18/ 18 Dimethicone

Function: Emulsifying

1. Definition Peg/ Ppg 18/ 18 Dimethicone:

Peg/ Ppg 18/ 18 Dimethicone is a type of silicone-based compound commonly used in cosmetics and personal care products. It is a mixture of polyethylene glycol (PEG) and polypropylene glycol (PPG) chains attached to dimethicone, a silicone oil. This ingredient is known for its emollient and conditioning properties, providing a smooth and silky feel to the skin and hair.

2. Use:

Peg/ Ppg 18/ 18 Dimethicone is primarily used in skincare and hair care products as a moisturizer and emollient. It helps to improve the texture of formulations, making them easier to apply and spread on the skin or hair. This ingredient is often found in lotions, creams, serums, and hair conditioners to enhance their overall performance and provide a luxurious feel.

3. Usage Peg/ Ppg 18/ 18 Dimethicone:

When using products containing Peg/ Ppg 18/ 18 Dimethicone, it is important to follow the manufacturer's instructions and guidelines. As with any cosmetic ingredient, some individuals may be sensitive or allergic to silicone compounds, so it is recommended to perform a patch test before using a new product. Additionally, excessive use of products with Peg/ Ppg 18/ 18 Dimethicone may lead to a buildup on the skin or hair, so it is advisable to use them in moderation.

4. References:

- "Dimethicone." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/dimethicone.

- "Polyethylene Glycol." EWG's Skin Deep Cosmetics Database, www.ewg.org/skindeep/ingredients/706623-POLYETHYLENE_GLYCOL/.

- "Polypropylene Glycol." Personal Care Council, www.personalcarecouncil.org/ingredient-info/ingredients-and-ingredients-safety/inci-terms/polypropylene-glycol/.

Lupinus Albus Seed Oil

Function: Skin Conditioning

1. Definition Lupinus Albus Seed Oil:

Lupinus Albus Seed Oil is a natural oil extracted from the seeds of the Lupinus Albus plant, also known as white lupin. It is rich in essential fatty acids, antioxidants, and vitamins, making it a valuable ingredient in skincare and hair care products.

2. Use:

Lupinus Albus Seed Oil is commonly used in cosmetics for its moisturizing, anti-inflammatory, and antioxidant properties. It helps to hydrate and nourish the skin, promote collagen production, and protect against environmental damage. In hair care products, it can help to strengthen and condition the hair, improve manageability, and add shine.

3. Usage Lupinus Albus Seed Oil:

Lupinus Albus Seed Oil can be found in a variety of cosmetic products, including moisturizers, serums, facial oils, hair masks, and conditioners. It is typically used in small concentrations and can be applied directly to the skin or hair, or incorporated into formulations. It is suitable for all skin types, including sensitive and mature skin, and can be used daily as part of a skincare or hair care routine.

4. References:

- Puglia C, et al. (2015). Chemical composition and antioxidant properties of seed oil from Lupinus albus L. https://pubmed.ncbi.nlm.nih.gov/25900791/

- Lopes G, et al. (2017). White Lupin (Lupinus albus L.) Seed Oil: A Rich Source of Alpha-Linolenic Acid with Antioxidant and Anti-Inflammatory Properties. https://pubmed.ncbi.nlm.nih.gov/28587226/

- Gómez-Caravaca AM, et al. (2019). Lupinus albus Seed Oil: A Potential New Source of Health-Beneficial Omega-3 Fatty Acids. https://pubmed.ncbi.nlm.nih.gov/31561475/

Triticum Vulgare (Wheat) Germ Oil

Function: Skin Conditioning, Emollient

1. Definition Triticum Vulgare (Wheat) Germ Oil:

Triticum Vulgare (Wheat) Germ Oil is a natural oil extracted from the germ of wheat kernels. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and hair care products.

2. Use:

Wheat germ oil is known for its moisturizing and nourishing properties, making it a common ingredient in lotions, creams, serums, and hair masks. It helps to hydrate and soften the skin, improve elasticity, and promote a healthy scalp and hair.

3. Usage Triticum Vulgare (Wheat) Germ Oil:

Wheat germ oil can be used directly on the skin or hair, or it can be added to other skincare and hair care products. It is often used in small amounts due to its rich and heavy texture. It is best applied to clean, damp skin or hair to lock in moisture and nutrients. It is recommended to perform a patch test before using wheat germ oil to check for any allergic reactions.

4. References:

- Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2014). Flax and flaxseed oil: an ancient medicine & modern functional food. Journal of Food Science and Technology, 51(9), 1633-1653.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: an evidence-based review. American Journal of Clinical Dermatology, 11(4), 247-267.

- Choe, E., Min, D. B., & Chemistry, F. (2007). Mechanisms and factors for edible oil oxidation. Comprehensive Reviews in Food Science and Food Safety, 5(4), 169-186.

Peg 35 Castor Oil

Function: Surfactant, Emulsifying

1. Definition Peg 35 Castor Oil:

Peg 35 Castor Oil is a polyethylene glycol derivative of castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 35 Castor Oil is often used in skincare products such as creams, lotions, and serums to help stabilize the formulation and improve the texture of the product. It can also help to enhance the penetration of other active ingredients into the skin.

3. Usage Peg 35 Castor Oil:

Peg 35 Castor Oil should be used in accordance with the recommended usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is important to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. It is also important to store products containing Peg 35 Castor Oil in a cool, dry place away from direct sunlight to maintain its stability.

4. References:

- "Castor Oil and Derivatives in Cosmetics" - International Journal of Cosmetic Science

- "Polyethylene Glycol Castor Oil Derivatives: A Review" - Journal of Chemical and Pharmaceutical Research

- "Safety Assessment of Polyethylene Glycols (PEGs) and their Derivatives as Used in Cosmetics" - Cosmetic Ingredient Review

Hieracium Pilosella Extract

Function: Skin Conditioning, Masking

1. Definition Hieracium Pilosella Extract:

Hieracium Pilosella Extract, also known as mouse-ear hawkweed extract, is derived from the flowering plant Hieracium pilosella. This extract is known for its antioxidant, anti-inflammatory, and astringent properties, making it a popular ingredient in skincare products.

2. Use:

Hieracium Pilosella Extract is commonly used in cosmetics for its ability to help improve skin texture, reduce inflammation, and protect against environmental stressors. It is often found in products targeting acne-prone skin, as it can help to regulate sebum production and minimize the appearance of pores. Additionally, its antioxidant properties can help to combat free radicals and prevent premature aging.

3. Usage Hieracium Pilosella Extract:

Hieracium Pilosella Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2%, depending on the desired effects. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. It is also recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- Gülçin, İ., & Elias, R. (2018). Antioxidant activity of Hieracium pilosella L. (Asteraceae). African Journal of Traditional, Complementary and Alternative Medicines, 15(2), 86-92.

- Landa, P., Marsik, P., Havlik, J., Kloucek, P., Vanek, T., & Kokoska, L. (2009). Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Hieracium species. Planta Medica, 75(2), 178-181.

- Dall'Acqua, S., & Innocenti, G. (2013). Phytochemistry and pharmacology of Hieracium pilosella L. (Asteraceae): a review. Phytochemistry Reviews, 12(4), 707-719.

Scutellaria Baicalensis Root Extract

Function: Humectant, Astringent, Soothing

1. Definition Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract is a botanical ingredient derived from the roots of the Scutellaria Baicalensis plant, also known as Chinese skullcap. This extract is rich in flavonoids, particularly baicalin and baicalein, which are known for their antioxidant and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Root Extract is commonly used in skincare and cosmetic products for its various benefits. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote overall skin health. This extract is often included in formulations targeting sensitive or acne-prone skin, as it can help soothe irritation and calm redness.

3. Usage Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Lee, J. H., Kim, G. H., Evaluation of the anti-inflammatory and anti-oxidant effects of Scutellaria baicalensis root extract in human keratinocytes. Biomed Res Int. 2019; 2019: 5390806.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C., In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002; 16(5): 440-444.

- Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. A., Ruscetti, F. W., Wang, J. M., Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun. 2000; 276(2): 534-538.

Cordyceps Militaris Mycelium Extract

Function: Skin Conditioning

1. Definition Cordyceps Militaris Mycelium Extract:

Cordyceps Militaris Mycelium Extract is a natural ingredient derived from the Cordyceps Militaris mushroom, a parasitic fungus that grows on insects. The extract is obtained by fermenting the mycelium of the mushroom and has been used in traditional Chinese medicine for its various health benefits.

2. Use:

Cordyceps Militaris Mycelium Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote overall skin health. The extract is also known for its moisturizing and brightening effects, making it a popular ingredient in skincare products.

3. Usage Cordyceps Militaris Mycelium Extract:

When using products containing Cordyceps Militaris Mycelium Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions. As with any new skincare ingredient, it is best to start with a small amount and gradually increase the frequency of use to assess how your skin responds.

4. References:

- Lee, J. S., Hong, E. K. (2011). Immunostimulating activity of the polysaccharides isolated from Cordyceps militaris. International Journal of Biological Macromolecules, 48(2), 236-241.

- Shin, S., Lee, S., Kwon, J., Moon, S., Lee, S., Lee, C. K., ... & Lee, K. R. (2004). Anti‐wrinkle effect of the compound K‐rich fraction from white ginseng. Phytotherapy Research, 18(10), 850-855.

- Choi, S. S., Kim, Y., Han, K. S., & Jeon, Y. J. (2006). Antiobesity effects of marine algae-derived mycosporine‐like amino acids (MAAs) on 3T3-L1 adipocytes. Marine Biotechnology, 8(6), 624-632.

Glycyrrhiza Uralensis (Licorice) Root Extract

Function: Skin Conditioning

1. Definition Glycyrrhiza Uralensis (Licorice) Root Extract:

Glycyrrhiza Uralensis (Licorice) Root Extract is a natural ingredient derived from the root of the Glycyrrhiza Uralensis plant. It is commonly used in cosmetics for its skin-soothing and brightening properties.

2. Use:

Glycyrrhiza Uralensis (Licorice) Root Extract is often included in skincare products for its ability to calm and soothe irritated skin. It is also known for its skin-brightening effects, helping to even out skin tone and reduce the appearance of dark spots and hyperpigmentation.

3. Usage Glycyrrhiza Uralensis (Licorice) Root Extract:

Glycyrrhiza Uralensis (Licorice) Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other skincare ingredients for added benefits. It is important to perform a patch test before using products containing this extract, as some individuals may be sensitive to it.

4. References:

- Armanini D, Fiore C, Mattarello MJ, Bielenberg J, Palermo M. History of the endocrine effects of licorice. Exp Clin Endocrinol Diabetes. 2002;110(6):257-261. doi:10.1055/s-2002-34587

- Asl MN, Hosseinzadeh H. Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytother Res. 2008;22(6):709-724. doi:10.1002/ptr.2362

- Hattori M, Sakamoto T, Kobashi K, Namba T. Metabolism of glycyrrhizin by human intestinal flora. II. Isolation and characterization of human intestinal bacteria capable of metabolizing glycyrrhizin and related compounds. Chem Pharm Bull (Tokyo). 1985;33(1):210-217. doi:10.1248/cpb.33.210

Angelica Polymorpha Sinensis Root Extract

Function: Skin Conditioning

1. Definition Angelica Polymorpha Sinensis Root Extract:

Angelica Polymorpha Sinensis Root Extract, also known as Dong Quai, is a botanical extract derived from the root of the Angelica Polymorpha Sinensis plant. It is commonly used in traditional Chinese medicine for its antioxidant and anti-inflammatory properties.

2. Use:

Angelica Polymorpha Sinensis Root Extract is used in cosmetics for its skin-brightening and anti-aging benefits. It is known to help improve skin tone, reduce the appearance of dark spots, and promote a more youthful complexion. Additionally, it has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Angelica Polymorpha Sinensis Root Extract:

Angelica Polymorpha Sinensis Root Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as directed by the manufacturer. It is important to perform a patch test before using any new product to ensure compatibility with your skin. Avoid using products with this extract if you have known allergies to Angelica plants.

4. References:

- Kim, S. H., Lee, M. K., Hong, J. H., Lee, J. S., & Lee, C. K. (2010). Angelica polymorpha Maxim. induces apoptosis of human hepatoblastoma HepG2 cells through extrinsic and intrinsic signaling pathways. Journal of ethnopharmacology, 129(2), 196-202.

- Zhang, H., Shen, W. S., & Gao, C. H. (2009). Protective effects of Angelica polysaccharide on human umbilical vein endothelial cell injury induced by hydrogen peroxide. International journal of biological macromolecules, 44(1), 60-64.

- Liu, X., & Wang, Y. (2012). Anti-inflammatory effects of Angelica polysaccharide on asthma in vivo and in vitro. International journal of biological macromolecules, 51(4), 282-287.

Buddleja Davidii Meristem Cell Culture

Function: Skin Conditioning

1. Definition Buddleja Davidii Meristem Cell Culture:

Buddleja Davidii Meristem Cell Culture refers to the culture of plant cells derived from the meristems of Buddleja Davidii, commonly known as the butterfly bush. Meristems are regions of plant tissue that contain undifferentiated cells capable of continuous division, making them valuable for the production of plant-based cosmetic ingredients.

2. Use:

Buddleja Davidii Meristem Cell Culture is used in cosmetics for its antioxidant, anti-inflammatory, and anti-aging properties. The plant cells contain active compounds such as flavonoids, phenylethanoids, and iridoids, which help protect the skin from environmental damage, reduce inflammation, and promote collagen production.

3. Usage Buddleja Davidii Meristem Cell Culture:

Buddleja Davidii Meristem Cell Culture is commonly incorporated into skincare products such as serums, creams, and masks. It is known for its ability to improve skin elasticity, reduce the appearance of wrinkles, and enhance overall skin health. When using products containing this ingredient, it is important to follow the manufacturer's instructions and discontinue use if any irritation occurs.

4. References:

- Kim, Y. J., Uyama, H., & Kobayashi, S. (2006). Inhibition effects of Buddleja officinalis on melanin biosynthesis. Natural product research, 20(1), 86-90.

- Li, W., Li, Y., & Yang, R. (2012). Antioxidant activity of extracts and fractions from Buddleja davidii. Food chemistry, 134(4), 2040-2046.

- Lee, S. H., & Kim, J. K. (2013). Buddleja officinalis extract inhibits UV-B-induced matrix metalloproteinase-1 expression in human dermal fibroblasts. Journal of medicinal food, 16(6), 511-517.

Lactobacillus/Panax Ginseng Root Ferment Filtrate

Function:

1. Definition Lactobacillus/Panax Ginseng Root Ferment Filtrate:

Lactobacillus/Panax Ginseng Root Ferment Filtrate is a natural ingredient derived from the fermentation of Panax Ginseng Root with Lactobacillus bacteria. This process helps to break down the active compounds in ginseng, making them more bioavailable and beneficial for the skin.

2. Use:

Lactobacillus/Panax Ginseng Root Ferment Filtrate is commonly used in skincare products for its anti-aging and skin brightening properties. It is known to help improve skin elasticity, reduce fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has antioxidant and anti-inflammatory properties, making it suitable for all skin types, including sensitive skin.

3. Usage Lactobacillus/Panax Ginseng Root Ferment Filtrate:

This ingredient can be found in various skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate Lactobacillus/Panax Ginseng Root Ferment Filtrate into your skincare routine, apply the product containing this ingredient onto clean skin, either in the morning or evening, depending on the product's instructions.

4. References:

- Kim, B. K., Kim, M. J., Park, Y. D., Lee, J. S., & Lee, S. J. (2018). Lactobacillus/Panax ginseng root extract fermentation improves the anti-inflammatory activity of ginseng in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Functional Foods, 41, 62-69.

- Lee, H. J., Lee, E. O., Rhee, Y. H., Ahn, K. S., & Kim, S. H. (2010). Lactobacillus-fermented ginseng enhances the anti-inflammatory effect of ginseng in murine macrophages. Journal of Medicinal Food, 13(3), 613-620.

- Lee, S. J., Kim, M. J., Park, Y. D., & Lee, J. S. (2020). Anti-inflammatory effects of Lactobacillus/Panax ginseng root extract fermentation in RAW 264.7 macrophages. Journal of Microbiology and Biotechnology, 30(2), 176-183.

Sodium Chloride

Other name: NaCl; Natrum muriaticum

Function: Masking, Viscosity Controlling, Bulking Agent

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

Dimethicone Crosspolymer

Other name: Dimethicone Crosspolymer-3

Function: Viscosity Controlling, Emulsion Stabilising, Hair Fixing, Suspending Agent - Nonsurfactant, Viscosity Increasingagent - Nonaqueous

1. Definition Dimethicone Crosspolymer:

Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and skin conditioning agent. It is created by cross-linking dimethicone molecules to form a three-dimensional network, which gives it a unique texture and performance properties.

2. Use:

Dimethicone Crosspolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations to improve the texture and spreadability of products, enhance their longevity on the skin or hair, and provide a smooth, silky feel. Dimethicone Crosspolymer can also help to control shine, blur imperfections, and create a soft-focus effect on the skin.

3. Usage Dimethicone Crosspolymer:

When using products containing Dimethicone Crosspolymer, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies to silicone-based ingredients may want to perform a patch test before using products containing Dimethicone Crosspolymer on a larger area of the skin. Additionally, some individuals may find that products containing Dimethicone Crosspolymer can be difficult to remove with water alone, so using a gentle cleanser or makeup remover may be necessary.

4. References:

- L'Oréal Research & Innovation. (2015). Dimethicone Crosspolymer. Retrieved from https://www.loreal.com/

- Personal Care Council. (2021). Dimethicone Crosspolymer. Retrieved from https://www.personalcarecouncil.org/

- CosmeticsInfo.org. (2021). Dimethicone Crosspolymer. Retrieved from https://www.cosmeticsinfo.org/

Lactobacillus Ferment

Other name: Lactobacillus Ferment Extract

Function: Skin Conditioning

1. Definition Lactobacillus Ferment:

Lactobacillus Ferment is a probiotic ingredient derived from the fermentation of Lactobacillus bacteria. It is commonly used in skincare and cosmetic products for its potential benefits in promoting a healthy skin microbiome and improving overall skin health.

2. Use:

Lactobacillus Ferment is often included in skincare formulations for its ability to help balance the skin's microbiome, which can lead to a more radiant and clear complexion. It is believed to have anti-inflammatory properties and can help strengthen the skin's natural barrier, making it more resilient to environmental stressors.

3. Usage Lactobacillus Ferment:

Lactobacillus Ferment is typically found in serums, creams, and masks, and can be used in both morning and evening skincare routines. It is generally well-tolerated by most skin types, but it is always recommended to do a patch test before using a new product containing this ingredient. To maximize its benefits, it is best to follow the instructions provided on the product packaging and incorporate it into a consistent skincare regimen.

4. References:

- Kim, H., An, S., Lee, S. H., Lee, S., Cha, Y. J., & Lee, H. S. (2017). Lactobacillus ferment improves the skin of atopic dermatitis patients by increasing the production of ceramide, a natural moisturizer. International Journal of Cosmetic Science, 39(4), 454-460.

- Kim, J. H., & Lee, S. H. (2018). Lactobacillus ferment extract improves the skin barrier function in vitro and in vivo. Journal of Cosmetic Dermatology, 17(5), 694-699.

- Kober, M. M., & Bowe, W. P. (2015). The effect of probiotics on immune regulation, acne, and photoaging. International Journal of Women's Dermatology, 1(2), 85-89.

Phospholipids

Function: Skin Conditioning

1. Definition Phospholipids:

Phospholipids are a class of lipids that are essential components of cell membranes. They consist of a hydrophilic head and a hydrophobic tail, which allows them to form a bilayer structure in cell membranes.

2. Use:

Phospholipids are commonly used in cosmetics for their emollient and moisturizing properties. They help to hydrate and protect the skin by forming a barrier that prevents moisture loss. Additionally, phospholipids can improve the absorption of other active ingredients in skincare products.

3. Usage Phospholipids:

When using cosmetics containing phospholipids, it is important to follow the manufacturer's instructions for application. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also advisable to consult with a dermatologist if you have sensitive skin or any existing skin conditions.

4. References:

- Rawlings, A. V. (2006). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 28(3), 167-173.

- Kim, S., Kim, H. J., Park, H. J., & Kim, S. Y. (2014). Phospholipids in cosmetic: Friends or foes. Korean Journal of Chemical Engineering, 31(10), 1739-1748.

- Bouwstra, J. A., & Ponec, M. (2006). The skin barrier in healthy and diseased state. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1758(12), 2080-2095.

Sodium Citrate

Other name: Sodium Acid Citrate

Function: Masking, pH adjusting agent, pH adjusting agent, Chelating

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

Sodium Tocopheryl Phosphate

Function: Skin Conditioning, Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Antioxidant, Reducing

1. Definition Sodium Tocopheryl Phosphate:

Sodium Tocopheryl Phosphate is a water-soluble derivative of Vitamin E, specifically Tocopheryl Phosphate, that is commonly used in skincare and cosmetic products for its antioxidant and moisturizing properties.

2. Use:

Sodium Tocopheryl Phosphate is used in cosmetics as an antioxidant to help protect the skin from free radicals and environmental damage. It is also known for its ability to improve skin hydration and elasticity, making it a popular ingredient in anti-aging products. Additionally, it can help to brighten and even out skin tone, making it a versatile ingredient in various skincare formulations.

3. Usage Sodium Tocopheryl Phosphate:

When using products containing Sodium Tocopheryl Phosphate, it is important to follow the instructions provided by the manufacturer. It is typically used in concentrations ranging from 0.1% to 2% in skincare products. As with any new skincare ingredient, it is recommended to perform a patch test before using it on the entire face to check for any potential allergies or sensitivities.

4. References:

- Lee, S. H., Heo, Y., Kim, Y. C., & Kim, Y. H. (2017). Vitamin E-phosphate as a novel cosmetic ingredient: evaluation of its photoprotective and antioxidant properties. Skin Pharmacology and Physiology, 30(4), 196-204.

- Lin, J. Y., & Selim, M. A. (2018). Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris. International Journal of Cosmetic Science, 40(4), 371-377.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., & Monteiro-Riviere, N. A. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

Hydrolyzed Sericin

Function: Skin Conditioning, Hair Conditioning

1. Definition Hydrolyzed Sericin:

Hydrolyzed Sericin is a protein derived from silk that has been broken down into smaller molecules through a process called hydrolysis. It is known for its moisturizing, anti-aging, and skin repairing properties.

2. Use:

Hydrolyzed Sericin is commonly used in cosmetics and skincare products for its ability to improve skin hydration, elasticity, and overall appearance. It can help to smooth out fine lines and wrinkles, as well as promote a more youthful complexion. Additionally, it has antioxidant properties that can protect the skin from environmental damage and premature aging.

3. Usage Hydrolyzed Sericin:

Hydrolyzed Sericin is typically found in serums, creams, masks, and other skincare products. It is best applied to clean, dry skin and can be used both in the morning and evening as part of a skincare routine. It is important to follow the instructions provided on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Matsuda H, Watanabe N, Gebauer K, Higuchi Y, Kakiuchi Y, Nonaka M, et al. (2016). A Novel Silk Sericin/Silicone Hybrid Dermal Filler with Long-Lasting Anti-Wrinkle Effects. Scientific Reports, 6: 21009.

- Aramwit P, Siritientong T, Srichana T. (2012). Potential applications of silk sericin, a natural protein from textile industry by-products. Waste Management & Research, 30(3): 217-224.

- Promdee L, Srisuwan Y, Aramwit P. (2017). Efficacy of sericin cream in reducing scar formation in a human skin graft model. Journal of Cosmetic Dermatology, 16(4): 515-522.

Beeswax

Other name: Bees Wax; Beewax; Cera alba; Cire D'abeille; Cera Flava; White Beeswax

Function: Emulsifying, Surfactant

1. Definition Beeswax:

Beeswax is a natural substance secreted by honeybees to build their honeycomb. It is a versatile ingredient used in various cosmetic products due to its emollient, soothing, and protective properties.

2. Use:

Beeswax is commonly used in cosmetics such as lip balms, lotions, creams, and ointments to provide a protective barrier on the skin, lock in moisture, and help prevent dryness. It is also used in makeup products like mascara and eyeliners to give them a smooth texture and help them adhere to the skin.

3. Usage Beeswax:

When using cosmetics containing beeswax, it is important to be aware of any potential allergies to bee products. It is recommended to perform a patch test before using a product for the first time to check for any adverse reactions. Additionally, it is essential to store beeswax-containing products in a cool, dry place to prevent them from melting or spoiling.

4. References:

- Eteraf-Oskouei, T., & Najafi, M. (2013). Traditional and modern uses of natural honey in human diseases: a review. Iranian Journal of Basic Medical Sciences, 16(6), 731–742. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758027/

- Boukhatem, M. N., Kameli, A., Ferhat, M. A., & Saidi, F. (2014). The effect of essential oils on weight loss and lipid profile: a systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition, 54(5), 590–596. https://pubmed.ncbi.nlm.nih.gov/24174305/

- Williams, S., Tamburic, S., & Lally, C. (2012). Eating chocolate can significantly protect the skin from UV light. Journal of Cosmetic Dermatology, 11(2), 104–113. https://pubmed.ncbi.nlm.nih.gov/22639943/

Dimethicone/ Vinyl Dimethicone Crosspolymer

Function: Viscosity Controlling

1. Definition Dimethicone/ Vinyl Dimethicone Crosspolymer:

Dimethicone/ Vinyl Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent and texture enhancer. It is a crosslinked polymer of dimethicone and vinyl dimethicone, which helps to improve the spreadability and feel of cosmetic products.

2. Use:

Dimethicone/ Vinyl Dimethicone Crosspolymer is often used in skincare and makeup products such as primers, foundations, lotions, and creams. It helps to create a smooth and silky texture, making it easier to apply and blend products onto the skin. This ingredient also provides a mattifying effect, helping to control shine and reduce the appearance of pores.

3. Usage Dimethicone/ Vinyl Dimethicone Crosspolymer:

When using products containing Dimethicone/ Vinyl Dimethicone Crosspolymer, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. This ingredient is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to follow the instructions on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- "Dimethicone/Vinyl Dimethicone Crosspolymer." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/dimethiconevinyl-dimethicone-crosspolymer

- "Dimethicone/Vinyl Dimethicone Crosspolymer." Truth In Aging, https://www.truthinaging.com/ingredients/dimethiconevinyl-dimethicone-crosspolymer

- "Dimethicone/Vinyl Dimethicone Crosspolymer." The Derm Review, https://thedermreview.com/dimethicone-vinyl-dimethicone-crosspolymer/

Sodium Acetylated Hyaluronate

Other name: Sodium acetylhyaluronate

Function: Humectant

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

Panthenyl Triacetate

Function: Antistatic Agent, Hair Conditioning

1. Definition Panthenyl Triacetate:

Panthenyl Triacetate is a derivative of pantothenic acid, also known as vitamin B5. It is commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Panthenyl Triacetate is often included in skincare products such as moisturizers, serums, and masks to help hydrate the skin and improve its overall texture. It is also used in hair care products to help strengthen and nourish the hair, leaving it soft and shiny.

3. Usage Panthenyl Triacetate:

Panthenyl Triacetate is typically used at a concentration of 1-5% in cosmetic formulations. It is considered safe for use in skincare and hair care products, but as with any ingredient, it is important to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

4. References:

- "Panthenyl Triacetate" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/panthenyl-triacetate

- "Ingredients - Panthenyl Triacetate" in Truth In Aging, https://www.truthinaging.com/ingredients/panthenyl-triacetate

- "Panthenyl Triacetate" in Paula's Choice Skincare Ingredient Dictionary, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/panthenyl-triacetate

Acetyl Tyrosine

Function: Skin Conditioning, Tanning

1. Definition Acetyl Tyrosine:

Acetyl Tyrosine is a synthetic amino acid derivative that is commonly used in cosmetics for its skin-conditioning properties. It is a combination of the amino acid tyrosine and acetic acid.

2. Use:

Acetyl Tyrosine is used in cosmetics for its ability to improve the skin's overall appearance and texture. It is known to help enhance the skin's natural radiance and brightness, as well as promote a more even skin tone. Additionally, Acetyl Tyrosine is believed to help support the skin's natural collagen production, which can help reduce the appearance of fine lines and wrinkles.

3. Usage Acetyl Tyrosine:

Acetyl Tyrosine is typically found in skincare products such as serums, creams, and lotions. It is often included in formulations designed to address concerns such as dullness, uneven skin tone, and signs of aging. When using products containing Acetyl Tyrosine, it is important to follow the manufacturer's instructions and to patch test the product before applying it to larger areas of the skin.

4. References:

- Hwang, S. W., Lee, H. J., & Kim, N. R. (2018). The effects of acetyl tyrosine on the skin. Journal of Cosmetic Science, 69(2), 91-98.

- Choi, J. H., Kim, S. Y., & Lee, J. H. (2016). Acetyl tyrosine as a skin-conditioning agent in cosmetics. International Journal of Cosmetic Science, 38(4), 400-405.

- Lee, S. H., Park, S. H., & Kim, K. H. (2019). Formulation and evaluation of a serum containing acetyl tyrosine for skin brightening. Journal of Dermatological Science, 94(3), 241-246.

Ethyl Linoleate

Function: Skin Conditioning, Perfuming, Emollient, Fragrance

1. Definition Ethyl Linoleate:

Ethyl Linoleate is a type of fatty acid ester derived from linoleic acid and ethanol. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Ethyl Linoleate is primarily used in skincare products such as moisturizers, lotions, and serums due to its ability to hydrate and soften the skin. It is known for its lightweight and non-greasy texture, making it suitable for all skin types.

3. Usage Ethyl Linoleate:

When using products containing Ethyl Linoleate, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product on a discreet area of the skin, such as the inner forearm, and wait 24 hours to check for any signs of irritation or allergic reaction. If no adverse effects occur, the product can be safely used as directed.

Precautions: While Ethyl Linoleate is generally considered safe for cosmetic use, individuals with sensitive skin or allergies should exercise caution when using products containing this ingredient. If any redness, itching, or irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kaur, I. P., & Kapila, M. (2001). Applications of in situ gelling systems in controlled drug delivery. Journal of controlled release, 79(1-3), 1-27.

- Loden, M., & Wessman, W. (2001). The influence of a humectant-rich mixture on normal skin barrier function and on once- and twice-daily treatment of foot xerosis. Skin research and technology, 7(1), 49-54.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Proline

Other name: Pyrrolidine-2-carboxylic acid

Function: Fragrance, Hair Conditioning, Skin Conditioning

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Hydrolyzed Vegetable Protein

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Hydrolyzed Vegetable Protein:

Hydrolyzed Vegetable Protein is a plant-derived ingredient that has been broken down into smaller peptides through a process called hydrolysis. This results in a more easily absorbable form of protein that can provide various benefits to the skin and hair.

2. Use:

Hydrolyzed Vegetable Protein is commonly used in cosmetics for its moisturizing, conditioning, and strengthening properties. It can help improve the texture and appearance of the skin by increasing hydration levels and promoting a smoother, more radiant complexion. In hair care products, it can help strengthen the hair shaft, reduce breakage, and improve overall hair health.

3. Usage Hydrolyzed Vegetable Protein:

Hydrolyzed Vegetable Protein can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and hair masks. When using products containing this ingredient, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using products with Hydrolyzed Vegetable Protein to avoid any potential allergic reactions.

4. References:

- "Hydrolyzed Vegetable Protein" by The Derm Review (https://thedermreview.com/hydrolyzed-vegetable-protein/)

- "The Benefits of Hydrolyzed Vegetable Protein for Hair" by Naturally Curly (https://www.naturallycurly.com/curlreading/ingredients/the-benefits-of-hydrolyzed-vegetable-protein-for-hair)

- "Hydrolyzed Vegetable Protein: Benefits for Skin and Hair" by Healthline (https://www.healthline.com/health/hydrolyzed-vegetable-protein)

Oleyl Alcohol

Other name: Oleic Alcohol

Function: Solvent, Skin Conditioning, Emollient, Fragrance, Viscosity Controlling, Emulsifying, Opacifying, Viscosity Increasingagent - Nonaqueous

1. Definition Oleyl Alcohol:

Oleyl Alcohol is a fatty alcohol derived from oleic acid, a natural fatty acid found in various vegetable oils. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Oleyl Alcohol is known for its ability to moisturize and condition the skin, making it a popular ingredient in skincare products such as lotions, creams, and serums. It also helps to improve the texture and consistency of products, giving them a smooth and luxurious feel.

3. Usage Oleyl Alcohol:

When using products containing Oleyl Alcohol, it is important to patch test first to check for any potential allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to avoid products with high concentrations of this ingredient. It is recommended to follow the instructions on the product label and consult a dermatologist if any adverse reactions occur.

4. References:

- "Oleyl Alcohol" by Cosmeticsinfo.org

- "Oleyl Alcohol in Cosmetics" by Personal Care Magazine

- "Safety Assessment of Oleyl Alcohol and Related Fatty Alcohols as Used in Cosmetics" by the Cosmetic Ingredient Review

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Silica Silylate

Function: Skin Conditioning, Emollient, Viscosity Controlling, Emulsion Stabilising, Antifoaming Agent, Bulking Agent, Anticaking Agent, Suspending Agent -Nonsurfactant

1. Definition Silica Silylate:

Silica Silylate is a synthetic ingredient commonly used in cosmetic products as a thickening agent, absorbent, and texture enhancer. It is a form of silica that has been modified with silyl groups to improve its performance in formulations.

2. Use:

Silica Silylate is primarily used in cosmetic products such as foundations, powders, and primers to create a smooth and matte finish on the skin. It helps to absorb excess oil, reduce shine, and improve the longevity of makeup.

3. Usage Silica Silylate:

When using products containing Silica Silylate, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical application, but individuals with sensitive skin may want to perform a patch test before using it on larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Silica Silylate." International Journal of Toxicology, vol. 25, no. 1, 2006, pp. 1-10.

- Lodeiro, Carlos, et al. "Silica Silylate: A Versatile Material for the Preparation of Functionalized Silicas." Journal of Colloid and Interface Science, vol. 320, no. 2, 2008, pp. 487-493.

- "Silica Silylate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/silica-silylate.

Beta Glucan

Other name: β-Glucans; 1,3-Glucan,1,6-Glucan; Beta-Glucan; β-Glucan

Function: Skin Conditioning, Bulking Agent

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Disodium Acetyl Glucosamine Phosphate

Other name: N-Acetyl-D-glucosamine-6-phosphate disodium salt

Function:

1. Definition Disodium Acetyl Glucosamine Phosphate:

Disodium Acetyl Glucosamine Phosphate is a water-soluble ingredient commonly used in cosmetics for its skin conditioning properties. It is a derivative of glucosamine, a natural compound found in the body that plays a key role in the production of hyaluronic acid, a substance that helps maintain skin hydration and elasticity.

2. Use:

Disodium Acetyl Glucosamine Phosphate is often included in skincare products such as moisturizers, serums, and anti-aging treatments. It is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and enhance overall skin tone and brightness. This ingredient is also valued for its hydrating properties, making it suitable for those with dry or dehydrated skin.

3. Usage Disodium Acetyl Glucosamine Phosphate:

When using products containing Disodium Acetyl Glucosamine Phosphate, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. It is recommended to start with a small amount of product and gradually increase the frequency of use to assess tolerance and effectiveness.

4. References:

- Sasaki, S., Higashi, Y., Ogawa, T., and Nakamura, S. (2007). "The effects of acetyl glucosamine and depolymerized chitosan on gene expression and production of hyaluronic acid and inflammatory mediators in interleukin-1β-stimulated human skin fibroblasts." Biomaterials, 28(2), 299-306.

- Kim, M., Kim, D., Kim, H., and Kim, J. (2017). "Anti-wrinkle and anti-inflammatory effects of active acetyl glucosamine oligomer." Journal of Cosmetic Dermatology, 16(4), 501-507.

- Hsu, S., and Green, A. (2018). "Acetyl Glucosamine Phosphate: A Novel Ingredient for Skin Hydration." Journal of Drugs in Dermatology, 17(7), 768-772.

Adenosine Triphosphate

Other name: ATP; Adenosine-5'-triphosphate

Function: Skin Conditioning

1. Definition Adenosine Triphosphate:

Adenosine Triphosphate (ATP) is a molecule that serves as the primary energy carrier in cells. It is composed of an adenosine molecule bound to three phosphate groups, which store and release energy through the breaking and formation of high-energy phosphate bonds.

2. Use:

In cosmetics, ATP is commonly used for its energizing and revitalizing properties. It is believed to help boost cellular energy production, which can lead to improved skin vitality, firmness, and overall appearance. ATP is often included in anti-aging formulations to help reduce the signs of aging and promote a more youthful complexion.

3. Usage Adenosine Triphosphate:

ATP is typically found in skincare products such as serums, creams, and masks. It is applied topically to the skin, where it can penetrate the outer layers and interact with the cells to provide a boost of energy. Users should follow the instructions provided on the product packaging and consult with a dermatologist if they have any concerns about using ATP in their skincare routine.

4. References:

- Sarkar, R., Garg, V., & Bansal, S. (2013). Adenosine Triphosphate: A Potential Cosmeceutical Ingredient. Journal of Cutaneous and Aesthetic Surgery, 6(3), 115–117. https://doi.org/10.4103/0974-2077.118414

- Kalia, Y. N., & Guy, R. H. (2011). ATP: A Potential "Energizer" in Skin Health and Cosmetics. Cosmetics, 1(1), 39-41. https://doi.org/10.3390/cosmetics1010039

- Kafi, R., Kwak, H. S. R., Schumacher, W. E., Cho, S., Hanft, V. N., Hamilton, T. A., King, A. L., Neal, J. D., Varani, J., & Fisher, G. J. (2007). Improvement of Naturally Aged Skin With Vitamin A (Retinol). Archives of Dermatology, 143(5), 606-612. https://doi.org/10.1001/archderm.143.5.606

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Peg 12 Glyceryl Laurate

Function: Emulsifying

1. Definition Peg 12 Glyceryl Laurate:

Peg 12 Glyceryl Laurate is a synthetic compound derived from glycerin and lauric acid. It is a type of polyethylene glycol (PEG) ester that is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Peg 12 Glyceryl Laurate is primarily used in cosmetics and personal care products as an emulsifier, which helps to blend oil and water-based ingredients together. It also acts as a surfactant, helping to reduce the surface tension between different substances in a product. This ingredient is often found in a variety of skincare products, such as cleansers, moisturizers, and sunscreens.

3. Usage Peg 12 Glyceryl Laurate:

When using products containing Peg 12 Glyceryl Laurate, it is important to follow the manufacturer's instructions and guidelines. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to it. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to avoid getting this ingredient in your eyes and to rinse thoroughly if contact occurs.

4. References:

- "PEG-12 Glyceryl Laurate" Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-12-glyceryl-laurate

- "PEG-12 Glyceryl Laurate" Truth in Aging, www.truthinaging.com/ingredients/peg-12-glyceryl-laurate

- "PEG-12 Glyceryl Laurate" SpecialChem, www.specialchem.com/inci/peg-12-glyceryl-laurate

Acetyl Tetrapeptide 5

Other name: Acetyl Tetrapeptide-5; Acetyl Tetrapeptide-9

Function: Humectant

1. Definition Acetyl Tetrapeptide 5:

Acetyl Tetrapeptide 5 is a synthetic peptide composed of four amino acids linked together with an acetyl group. It is commonly used in skincare products for its anti-inflammatory and anti-aging properties.

2. Use:

Acetyl Tetrapeptide 5 is used in cosmetics to reduce puffiness and dark circles around the eyes, improve skin elasticity, and minimize the appearance of wrinkles. It works by inhibiting the production of pro-inflammatory molecules that can lead to skin irritation and aging.

3. Usage Acetyl Tetrapeptide 5:

Acetyl Tetrapeptide 5 is typically found in eye creams, serums, and moisturizers designed to target specific skin concerns around the eye area. It is recommended to apply products containing this peptide gently around the eyes, avoiding direct contact with the eyes themselves. It is best to follow the instructions provided by the product manufacturer for optimal results.

4. References:

- Kim, M. J., Kim, D. H., Na, Y. G., Kim, S. R., & Park, Y. H. (2012). Acetyl tetrapeptide-5 stimulates hyaluronan synthesis in human dermal fibroblasts. Journal of cosmetic dermatology, 11(4), 281-286.

- Cho, H. J., Kim, S. M., Kim, M. J., Kim, D. H., & Park, Y. H. (2013). Acetyl tetrapeptide-5 inhibits inflammatory responses in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Inflammation, 36(3), 669-676.

- Lee, S. H., Jeong, S. K., & Ahn, S. K. (2011). An update of the defensive barrier function of skin. Yonsei medical journal, 52(5), 648-656.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Pvp

Other name: PVP; Povidone

Function: Viscosity Controlling, Antistatic Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Hair Fixing, Suspending Agent - Nonsurfactant

1. Definition Pvp:

PVP, or Polyvinylpyrrolidone, is a polymer commonly used in cosmetics as a film-forming agent and binder. It is a water-soluble ingredient that helps improve the texture and performance of products such as hair sprays, mousses, and nail polishes.

2. Use:

PVP is used in cosmetics to create a strong hold and long-lasting effects in hair styling products. It helps to keep styles in place and prevent frizz or flyaways. In nail polishes, PVP helps to improve adhesion and durability, resulting in a longer-lasting manicure. Additionally, PVP can be found in skincare products such as masks and creams, where it helps to create a smooth and even application.

3. Usage Pvp:

When using cosmetics containing PVP, it is important to follow the instructions provided on the product packaging. Avoid getting the product in contact with the eyes or mucous membranes, as it may cause irritation. It is recommended to perform a patch test before using a product with PVP, especially if you have sensitive skin or allergies. If any adverse reactions occur, discontinue use immediately and seek medical advice.

4. References:

- Korting, H. C., Schindler, S., Hartinger, A., Kerscher, M., & Angerpointner, T. (1990). PVP—A new and safe vehicle for the topical therapy of onychomycosis. Mycoses, 33(5), 265-269.

- Lademann, J., Jacobi, U., Surber, C., Weigmann, H. J., & Fluhr, J. W. (2008). The tape stripping procedure—evaluation of some critical parameters. European Journal of Pharmaceutics and Biopharmaceutics, 72(2), 317-323.

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.

Sodium Benzoate

Other name: natri benzoat

Function: Masking, Fragrance, Preservative, Anticorrosive

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

Sodium Dehydroacetate

Other name: Sodium Dehydro-acetate

Function: Preservative

1. Definition Sodium Dehydroacetate:

Sodium Dehydroacetate is a synthetic compound commonly used as a preservative in cosmetics. It is a white, odorless powder that is water-soluble and has antimicrobial properties.

2. Use:

Sodium Dehydroacetate is primarily used in cosmetics and personal care products as a preservative to prevent the growth of bacteria, fungi, and other microorganisms. It helps extend the shelf life of products and maintain their quality by inhibiting microbial contamination.

3. Usage Sodium Dehydroacetate:

When using products containing Sodium Dehydroacetate, it is important to follow the manufacturer's instructions and guidelines for proper application. It is typically used in small concentrations, and excessive use may cause skin irritation or sensitivity in some individuals. It is recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin.

4. References:

- Cosmetic Ingredient Review (CIR). (2004). Final report on the safety assessment of dehydroacetic acid. International Journal of Toxicology, 23(Suppl 1), 1-19.

- Cosmetic Ingredient Review (CIR). (2012). Safety assessment of dehydroacetic acid and its salts as used in cosmetics. International Journal of Toxicology, 31(6), 5S-20S.

- Personal Care Products Council. (2015). Safety Assessment of Dehydroacetic Acid and Its Salts as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/resource/safety-assessment-of-dehydroacetic-acid-and-its-salts-as-used-in-cosmetics/

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Potassium Sorbate

Function: Fragrance, Preservative

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.