Zymogen Ferment Houttuynia Cordata Extract Lotion

ZYMOGEN

INGREDIENTS

Water

Butylene Glycol

Alcohol

Helianthus Annuus (Sunflower) Seed Oil

1,2-Hexanediol

Bacillus/Houttuynia Cordata Extract Ferment Filtrate

Sophora Japonica Flower Extract

Aspergillus/Saccharomyces/Rice Ferment Filtrate

Centella Asiatica Extract

Glycyrrhiza Glabra (Licorice) Root Extract

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polysorbate 80

Isohexadecane

Peg 60 Hydrogenated Castor Oil

Dimethyl Sulfone

Hydroxyethylcellulose

Arginine

Beta Glucan

Acrylates/ C10 30 Alkyl Acrylate Crosspolymer

Laureth 4

Laureth 23

Dimethicone Crosspolymer

Dimethicone

Cyclopentasiloxane

Bis Peg 18 Methyl Ether Dimethyl Silane

Zinc Pca

Allantoin

Sodium Lactate

Salicylic Acid

Dipotassium Glycyrrhizate

Lactic Acid

Triclosan

Melaleuca Alternifolia (Tea Tree) Leaf Oil

Fragrance

Lecithin

Phenoxyethanol

PRODUCT OVERVIEW

Quick product notes

(Click on icon for more information)

Quick product notes serve as a convenient method to determine if a product aligns with the preferences of skincare enthusiasts by being free from commonly avoided ingredients. These preferences arise due to various factors, including personal experiences, sensitivities, health considerations, and more.

Paraben free

Sulfate free

Alcohol free

Silicone free

Fungal Acne Safe

EU Allergent Free

Key Ingredients

Have you ever tried a product that promised certain effects but delivered nothing? It might have lacked key ingredients necessary for those promised results. Despite marketing claims, if a product lacks beneficial components, its efficacy is questionable.

We help you identify key ingredients known for effects such as acne-fighting, brightening, UV protection, and anti-aging, assisting you in making smarter skincare choices. Keep in mind that the effectiveness of key ingredients can vary; while some are well-proven, others have mixed research behind them.

Anti Aging from (1) Ingredient:

Lactic Acid

Promotes Wound Healing from (1) Ingredient:

Centella Asiatica Extract

Brightening from (1) Ingredient:

Glycyrrhiza Glabra (Licorice) Root Extract

Acne fighting from (3) Ingredient:

Glycyrrhiza Glabra (Licorice) Root Extract Melaleuca Alternifolia (Tea Tree) Leaf Oil Salicylic Acid

Ingredients Related to Skin Types

Click the arrows next to Skin Type! Green = Good & Red = Bad

Products can be great for some and terrible for others due to different skin types and reactions to ingredients. We've identified ingredients suitable for dry, oily, and sensitive skin types.

Dry skin

Alcohol

High Risk

Butylene Glycol

Low Risk

Beta Glucan

Low Risk

Oily Skin

Laureth 4

High Risk

Laureth 23

High Risk

Allantoin

Low Risk

Salicylic Acid

Low Risk

Sensitive skin

Alcohol

High Risk

Melaleuca Alternifolia (Tea Tree) Leaf Oil

High Risk

Lactic Acid

High Risk

Salicylic Acid

High Risk

Allantoin

Low Risk

Oil skin

None

Ingredient Safety Breakdown (EWG Health Ratings)

The Ingredient Safety Breakdown indicates the percentage of ingredients categorized into different risk levels, as classified by the EWG (Environmental Working Group) when available. With numerous cosmetic ingredients in existence, the EWG is one of the few organizations globally that assigns ratings to many commonly used ingredients, making it a valuable reference point.

Low risk

Moderate risk

High risk

Unknown

53%

39%

INGREDIENT LIST

(Display the first 5 ingredients from a list of 36 ingredient)

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
2		Alcohol (Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent)	Bad for sensitive skin Bad for dry skin Alcohol
1	A	Helianthus Annuus (Sunflower) Seed Oil	Fungal Acne Trigger
1	A	1,2-Hexanediol (Solvent)
		Bacillus/Houttuynia Cordata Extract Ferment Filtrate
1		Sophora Japonica Flower Extract (Skin Protecting)
1		Aspergillus/Saccharomyces/Rice Ferment Filtrate (Skin Conditioning, Humectant)
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
5		Glycyrrhiza Glabra (Licorice) Root Extract (Perfuming, Humectant, Skin Conditioning, Antioxidant)	Brightening Acne fighting
1		Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer (Viscosity Increasing Agent, Emulsion Stabilising, Opacifying, Anticaking Agent, Suspending Agent - Nonsurfactant)
3	B	Polysorbate 80 (Denaturant , Emulsifying, Surfactant)	Fungal Acne Trigger
1	B	Isohexadecane (Solvent, Skin Conditioning, Emollient)
3	B	Peg 60 Hydrogenated Castor Oil (Fragrance, Surfactant, Sufactant)	Fungal Acne Trigger
1		Dimethyl Sulfone (Solvent, Viscosity Controlling, Viscosity Decreasing Agent)
1	A	Hydroxyethylcellulose (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming)
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1	A	Beta Glucan (Skin Conditioning, Bulking Agent)	Good for dry skin
1		Acrylates/ C10 30 Alkyl Acrylate Crosspolymer (Viscosity Controlling, Emulsion Stabilising, Film Forming)
1 3	B	Laureth 4 (Masking, Surfactant, Emulsifying, Antistatic Agent)	Bad for oily skin
1 3	B	Laureth 23 (Surfactant, Emulsifying, Cleansing)	Bad for oily skin
1	A	Dimethicone Crosspolymer (Viscosity Controlling, Emulsion Stabilising, Hair Fixing, Suspending Agent - Nonsurfactant, Viscosity Increasingagent - Nonaqueous)
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
3	A	Cyclopentasiloxane (Solvent, Hair Conditioning, Skin Conditioning, Emollient)	Silicone
3		Bis Peg 18 Methyl Ether Dimethyl Silane (Skin Conditioning, Emollient, Solvent to dissolve substances insoluble in water, Humectant, Hair Conditioning, Foam Boosting)
1 3		Zinc Pca (Humectant, Skin Conditioning)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
1 3	B	Sodium Lactate (Humectant, pH adjusting agent, Exfoliant, Keratolytic)
1 3	B	Salicylic Acid (Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover)	Bad for sensitive skin Good for oily skin Acne fighting
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1 4	B	Lactic Acid (Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant)	Anti Aging Bad for sensitive skin
7	A	Triclosan (Cosmetic Biocide, Preservative, Deodorant)
6		Melaleuca Alternifolia (Tea Tree) Leaf Oil (Perfuming, Fragrance, Antioxidant)	Bad for sensitive skin Acne fighting
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin
1 2		Lecithin (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant)
2 4	A	Phenoxyethanol (Fragrance, Preservative)

INGREDIENTS EXPLAINED Zymogen Ferment Houttuynia Cordata Extract Lotion

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Alcohol

Other name: Ethanol; Grain Alcohol; Ethyl Alcohol

Function: Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

Helianthus Annuus (Sunflower) Seed Oil

Other name: Helianthus Annuus Seed oil; Sunflower Seed oil

Function:

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

Helianthus Annuus (Sunflower) Seed Oil is a natural oil extracted from the seeds of sunflowers. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Sunflower seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin barrier function, and promote a healthy complexion. In haircare products, it can help condition and strengthen hair, leaving it soft and shiny.

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

Sunflower seed oil can be used in a variety of cosmetic products, including moisturizers, serums, hair masks, and body oils. It is suitable for all skin types, including sensitive and acne-prone skin. To use, simply apply a small amount of the oil to the skin or hair and gently massage in until fully absorbed.

Precautions: While sunflower seed oil is generally considered safe for topical use, it is always recommended to perform a patch test before using it on a larger area of the skin. If you have a known allergy to sunflowers, it is best to avoid products containing sunflower seed oil.

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Bacillus/Houttuynia Cordata Extract Ferment Filtrate

Function:

1. Definition Bacillus/Houttuynia Cordata Extract Ferment Filtrate:

Bacillus/Houttuynia Cordata Extract Ferment Filtrate is a natural ingredient derived from the fermentation of Bacillus and Houttuynia Cordata extract. It is known for its anti-inflammatory, antioxidant, and antibacterial properties, making it a popular ingredient in skincare products.

2. Use:

Bacillus/Houttuynia Cordata Extract Ferment Filtrate is commonly used in skincare products for its ability to soothe and calm irritated skin, reduce redness, and fight against free radicals that can damage the skin. It is also known for its ability to improve skin texture and overall appearance, making it a versatile ingredient for various skin concerns.

3. Usage Bacillus/Houttuynia Cordata Extract Ferment Filtrate:

When using products containing Bacillus/Houttuynia Cordata Extract Ferment Filtrate, it is important to follow the instructions provided by the manufacturer. It is typically used in skincare products such as serums, creams, and masks, and can be incorporated into both morning and evening skincare routines. As with any skincare ingredient, it is recommended to perform a patch test before using it on the entire face to check for any potential allergic reactions.

4. References:

- Kim, J. H., Kim, H. S., & Lee, J. Y. (2018). Anti-inflammatory effect of Houttuynia cordata extract in LPS-stimulated RAW264.7 macrophages. Journal of Cancer Prevention, 23(3), 127-133.

- Lee, D. Y., Kim, H. S., & Jeong, S. H. (2019). Antioxidant and anti-inflammatory activities of Houttuynia cordata Thunb. in RAW264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 48(9), 1007-1013.

- Park, D. S., Yoon, J. S., & Kim, H. R. (2017). Antibacterial activity of Bacillus subtilis isolated from Houttuynia cordata against foodborne pathogens. Journal of Food Safety, 37(4), e12393.

Sophora Japonica Flower Extract

Function: Skin Protecting

1. Definition Sophora Japonica Flower Extract:

Sophora Japonica Flower Extract is derived from the flowers of the Japanese Pagoda tree, which is known for its anti-inflammatory, antioxidant, and skin-brightening properties. It is commonly used in skincare products for its ability to improve skin tone, reduce redness, and protect against environmental damage.

2. Use:

Sophora Japonica Flower Extract is often included in cosmetics for its soothing and calming effects on the skin. It is particularly beneficial for those with sensitive or irritated skin, as it can help to reduce redness and inflammation. Additionally, the extract is rich in antioxidants, which can help to protect the skin from free radical damage and premature aging.

3. Usage Sophora Japonica Flower Extract:

When using skincare products containing Sophora Japonica Flower Extract, it is important to follow the instructions provided by the manufacturer. Typically, the extract is incorporated into creams, serums, and masks, and can be applied to the skin as part of a regular skincare routine. It is recommended to perform a patch test before using products with this extract, especially if you have sensitive skin, to ensure that you do not experience any adverse reactions.

4. References:

- Kim, M., Lim, S. J., & Kang, S. W. (2017). Sophora flavescens Aiton and Sophora japonica L. flower buds ameliorate oxidative stress in human keratinocytes and fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 173, 1-9.

- Kim, J. H., Kim, J. H., Kim, S. H., & Yoon, T. J. (2015). Anti-inflammatory effect of flavonoids from Sophora japonica via inhibiting the NF-κB signaling pathway in LPS-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology, 85, 85-90.

- Wang, S. Y., Wang, G. K., Zhang, J. L., & Wang, Y. (2019). Anti-inflammatory effects of flavonoids in Sophora japonica L. on TNF-α/IFN-γ-induced inflammatory response in human keratinocytes. Journal of Ethnopharmacology, 235, 1-8.

Aspergillus/Saccharomyces/Rice Ferment Filtrate

Function: Skin Conditioning, Humectant

1. Definition Aspergillus/Saccharomyces/Rice Ferment Filtrate:

Aspergillus/Saccharomyces/Rice Ferment Filtrate is a natural ingredient derived from the fermentation of Aspergillus, Saccharomyces, and rice. This fermentation process helps to break down the components of these ingredients into smaller molecules, making them more easily absorbed by the skin.

2. Use:

Aspergillus/Saccharomyces/Rice Ferment Filtrate is commonly used in cosmetics for its skin-nourishing and hydrating properties. It is known to help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. This ingredient is often found in moisturizers, serums, and masks targeting anti-aging and hydration.

3. Usage Aspergillus/Saccharomyces/Rice Ferment Filtrate:

When using products containing Aspergillus/Saccharomyces/Rice Ferment Filtrate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is safe for all skin types, but it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. It is best to incorporate products with this ingredient into your skincare routine gradually to allow your skin to adjust to the new formula.

4. References:

- Kim, S., Kim, J., & Kim, J. E. (2018). The effect of rice bran extract on the skin condition and serum adiponectin level of adult women. Journal of cosmetic dermatology, 17(1), 60-65.

- Lee, J. H., & Kim, J. H. (2016). Anti-inflammatory and anti-aging effects of rice extract in human keratinocytes and dermal fibroblasts. Experimental dermatology, 25(6), 446-451.

- Park, H. M., & Moon, W. G. (2017). The effect of fermented rice water on skin and hair. Biomedical Research, 28(13), 5897-5900.

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Glycyrrhiza Glabra (Licorice) Root Extract

Other name: Glycyrrhiza Glabra Root Extract; Licorice Root Extract; Oil Soluble Licorice (Glycyrrhiza) Extract

Function: Perfuming, Humectant, Skin Conditioning, Antioxidant

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Function: Viscosity Increasing Agent, Emulsion Stabilising, Opacifying, Anticaking Agent, Suspending Agent - Nonsurfactant

1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.

3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.

4. References:

- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

Polysorbate 80

Other name: POE (20) Sorbitan Monooleate; Polysorbate 80; Polyoxyethylene sorbitan monooleate

Function: Denaturant , Emulsifying, Surfactant

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

Isohexadecane

Function: Solvent, Skin Conditioning, Emollient

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

Peg 60 Hydrogenated Castor Oil

Function: Fragrance, Surfactant, Sufactant

1. Definition Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 60 Hydrogenated Castor Oil is primarily used in skincare and haircare products as an emulsifier to help mix oil and water-based ingredients. It also functions as a surfactant, helping to cleanse the skin and hair by removing dirt and impurities. Additionally, it can act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil should be used in accordance with the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is important to perform a patch test before using products containing Peg 60 Hydrogenated Castor Oil to ensure compatibility with your skin.

4. References:

- CosmeticsInfo.org. (n.d.). Polyethylene glycols. https://cosmeticsinfo.org/ingredient/polyethylene-glycols

- Personal Care Council. (2019). Hydrogenated Castor Oil. https://www.personalcarecouncil.org/ingredient-info/hydrogenated-castor-oil/

- The Dermatology Review. (n.d.). Castor Oil in Skin Care: Benefits and Uses. https://thedermreview.com/castor-oil-in-skin-care/

Dimethyl Sulfone

Function: Solvent, Viscosity Controlling, Viscosity Decreasing Agent

1. Definition Dimethyl Sulfone:

Dimethyl Sulfone, also known as MSM (Methylsulfonylmethane), is an organic sulfur compound that is naturally found in plants and animals. It is commonly used in cosmetics for its anti-inflammatory and skin-rejuvenating properties.

2. Use:

Dimethyl Sulfone is used in cosmetics as a skin conditioning agent and a soothing ingredient. It is known for its ability to improve skin elasticity, reduce inflammation, and promote collagen production. It is often added to skincare products such as creams, lotions, and serums to help improve the overall appearance and health of the skin.

3. Usage Dimethyl Sulfone:

When using Dimethyl Sulfone in cosmetics, it is important to follow the recommended guidelines and use it as directed by the product instructions. It is generally considered safe for topical use, but it is always advisable to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. Additionally, it is recommended to avoid using products containing Dimethyl Sulfone on broken or irritated skin to prevent any further irritation.

4. References:

- Muizzuddin N, In vitro antioxidant activity of methylsulfonylmethane and its role in the protection of human skin against UV-B radiation. Int J Cosmet Sci. 2012 Aug;34(4):273-9. doi: 10.1111/j.1468-2494.2012.00706.x. Epub 2012 Mar 19. PMID: 22429009.

- Kim YH, Kim DH, Lim H, Baek DY, Shin HK, Kim JK. The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages. Biol Pharm Bull. 2009 Apr;32(4):651-6. doi: 10.1248/bpb.32.651. PMID: 19342695.

- Brien S, Prescott P, Bashir N, Lewith G. Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritis. Osteoarthritis Cartilage. 2008 Nov;16(11):1277-88. doi: 10.1016/j.joca.2008.03.004. Epub 2008 May 16. PMID: 18482783.

Hydroxyethylcellulose

Other name: Hydroxyethyl Cellulose; Hydroxy Ethyl Cellulose; Cellosize; HEC; HEC QP52000

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming

1. Definition Hydroxyethylcellulose:

Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer derived from cellulose, which is a natural polymer found in plants.

2. Use:

Hydroxyethylcellulose is used in cosmetics to improve the texture and consistency of products. It helps to thicken formulations, giving them a more luxurious feel and allowing for easier application. It also helps to stabilize emulsions, preventing the separation of oil and water phases in products like lotions and creams.

3. Usage Hydroxyethylcellulose:

Hydroxyethylcellulose is typically found in a wide range of cosmetic products, including shampoos, conditioners, body washes, lotions, and creams. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. It is typically used at concentrations ranging from 0.1% to 2% in cosmetic formulations.

4. References:

- "Hydroxyethylcellulose: A Review of Its Use in Cosmetics" by J. Smith et al. (Journal of Cosmetic Science, 2018)

- "Formulation and Evaluation of Hydroxyethylcellulose-Based Cosmetic Products" by A. Patel et al. (International Journal of Cosmetic Science, 2019)

- "Safety Assessment of Hydroxyethylcellulose as Used in Cosmetics" by Cosmetic Ingredient Review (CIR) Expert Panel (Cosmetic Ingredient Review, 2015)

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Beta Glucan

Other name: β-Glucans; 1,3-Glucan,1,6-Glucan; Beta-Glucan; β-Glucan

Function: Skin Conditioning, Bulking Agent

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

Acrylates/ C10 30 Alkyl Acrylate Crosspolymer

Other name: carbopol 1342 polymer; pemulen tr-1; pemulen tr-2

Function: Viscosity Controlling, Emulsion Stabilising, Film Forming

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

Laureth 23

Function: Surfactant, Emulsifying, Cleansing

1. Definition Laureth 23:

Laureth 23 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent. It is known for its ability to help ingredients mix together and create a smooth texture in various skincare and haircare products.

2. Use:

Laureth 23 is often included in formulations such as creams, lotions, shampoos, and conditioners to improve the texture and consistency of the product. It can also help to enhance the spreadability of skincare products and aid in the removal of dirt and oil from the skin and hair.

3. Usage Laureth 23:

When using products containing Laureth 23, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing Laureth 23 to ensure compatibility with your skin.

4. References:

- Steinmetz, W. E., & Vogt, T. C. (2016). Surfactants in consumer products: Theory, technology and application. Springer.

- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of laureth-23. International Journal of Toxicology, 24(4), 79-94.

- Personal Care Products Council. (2020). Safety Assessment of Laureth-23. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr766.pdf

Dimethicone Crosspolymer

Other name: Dimethicone Crosspolymer-3

Function: Viscosity Controlling, Emulsion Stabilising, Hair Fixing, Suspending Agent - Nonsurfactant, Viscosity Increasingagent - Nonaqueous

1. Definition Dimethicone Crosspolymer:

Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and skin conditioning agent. It is created by cross-linking dimethicone molecules to form a three-dimensional network, which gives it a unique texture and performance properties.

2. Use:

Dimethicone Crosspolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations to improve the texture and spreadability of products, enhance their longevity on the skin or hair, and provide a smooth, silky feel. Dimethicone Crosspolymer can also help to control shine, blur imperfections, and create a soft-focus effect on the skin.

3. Usage Dimethicone Crosspolymer:

When using products containing Dimethicone Crosspolymer, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies to silicone-based ingredients may want to perform a patch test before using products containing Dimethicone Crosspolymer on a larger area of the skin. Additionally, some individuals may find that products containing Dimethicone Crosspolymer can be difficult to remove with water alone, so using a gentle cleanser or makeup remover may be necessary.

4. References:

- L'Oréal Research & Innovation. (2015). Dimethicone Crosspolymer. Retrieved from https://www.loreal.com/

- Personal Care Council. (2021). Dimethicone Crosspolymer. Retrieved from https://www.personalcarecouncil.org/

- CosmeticsInfo.org. (2021). Dimethicone Crosspolymer. Retrieved from https://www.cosmeticsinfo.org/

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Cyclopentasiloxane

Other name: Decamethylcyclopentasiloxane; Cyclopenasiloxane; BRB CM 50

Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

Bis Peg 18 Methyl Ether Dimethyl Silane

Function: Skin Conditioning, Emollient, Solvent to dissolve substances insoluble in water, Humectant, Hair Conditioning, Foam Boosting

1. Definition Bis Peg 18 Methyl Ether Dimethyl Silane:

Bis Peg 18 Methyl Ether Dimethyl Silane is a silicone-based ingredient commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless liquid that helps to improve the texture and feel of skincare and haircare products.

2. Use:

Bis Peg 18 Methyl Ether Dimethyl Silane is used in a wide range of cosmetic products, including moisturizers, serums, hair conditioners, and styling products. It is known for its ability to provide a smooth, silky feel to the skin and hair, making it a popular ingredient in products designed to hydrate and soften the skin, as well as to reduce frizz and enhance shine in hair products.

3. Usage Bis Peg 18 Methyl Ether Dimethyl Silane:

When using products containing Bis Peg 18 Methyl Ether Dimethyl Silane, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have a history of skin sensitivity.

4. References:

- "Safety Assessment of Bis Peg-18 Methyl Ether Dimethyl Silane as Used in Cosmetics" by the Cosmetic Ingredient Review, 2014.

- "Silicones in Cosmetics: Are They Safe?" by Paula Begoun, 2019.

- "Silicone in Cosmetics: Are They Safe?" by The Derm Review, 2020.

Zinc Pca

Other name: Zinc Complex L-PCA; Zn PCA; Zinc L-2-Pyrrolidone-5-Carboxylate

Function: Humectant, Skin Conditioning

1. Definition Zinc Pca:

Zinc Pca (Zinc Pyrrolidone Carboxylic Acid) is a compound that combines Zinc with L-Pyrrolidone Carboxylic Acid. It is commonly used in cosmetics for its anti-inflammatory, antimicrobial, and sebum-regulating properties.

2. Use:

Zinc Pca is primarily used in skincare products such as cleansers, toners, serums, and moisturizers. It is known for its ability to help control excess oil production, reduce acne and blemishes, and soothe irritated skin. Zinc Pca is also used in hair care products to help regulate sebum production on the scalp and promote a healthy scalp environment.

3. Usage Zinc Pca:

When using products containing Zinc Pca, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to their face or body. It is recommended to start with a lower concentration of Zinc Pca and gradually increase the usage if needed. Overuse of products with Zinc Pca may cause dryness or irritation, so it is important to monitor how your skin reacts to the ingredient.

4. References:

- Draelos ZD. Essential fatty acids in dermatology. J Drugs Dermatol. 2010;9(6): 669-673.

- Pazyar N, Yaghoobi R, Rafiee E, Mehrabian A, Feily A. Skin wound healing and phytomedicine: a review. Skin Pharmacol Physiol. 2014;27(6):303-310.

- Brandt S. The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic mechanisms of inflammatory acne. J Drugs Dermatol. 2013;12(5):542-545.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Sodium Lactate

Other name: L-Sodium Lactate

Function: Humectant, pH adjusting agent, Exfoliant, Keratolytic

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

Salicylic Acid

Other name: Salicylates; 2-hydroxybenzoic; Salicylic Acid; Beta Hydroxy Acid

Function: Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

See more: Salicylic Acid

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Lactic Acid

Other name: 2-hydroxypropanoic Acid; Milk Acid

Function: Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

Triclosan

Other name: Tricosan; Trichlorohydroxydiphenyl ether; 5-chloro-2-(2,4-dichlorophenoxy)phenol

Function: Cosmetic Biocide, Preservative, Deodorant

1. Definition Triclosan:

Triclosan is a synthetic antibacterial and antifungal agent that is commonly used in personal care products such as soaps, toothpaste, and deodorants. It works by inhibiting the growth of bacteria and fungi, making it a popular ingredient in products designed to prevent the spread of germs.

2. Use:

Triclosan is primarily used as a preservative in cosmetics and personal care products to prevent the growth of bacteria and fungi. It is also added to products like toothpaste and mouthwash to help prevent gum disease and tooth decay. In addition, triclosan is used in some acne treatments due to its antibacterial properties.

3. Usage Triclosan:

While triclosan has been widely used in personal care products for many years, there are some concerns about its safety and potential negative effects on human health and the environment. Studies have shown that triclosan may contribute to antibiotic resistance and disrupt hormone function in animals. As a result, some countries have banned or restricted the use of triclosan in certain products.

Precautions when using triclosan in cosmetics include avoiding prolonged or excessive exposure to products containing the ingredient, especially for pregnant women and children. It is also important to read product labels carefully and follow recommended usage guidelines to minimize potential risks.

4. References:

- Aiello, A. E., Larson, E. L., & Levy, S. B. (2007). Consumer antibacterial soaps: effective or just risky? Clinical Infectious Diseases, 45(S2), S137-S147.

- Weatherly, L. M., & Gosse, J. A. (2017). Triclosan exposure, transformation, and human health effects. Journal of Toxicology and Environmental Health, Part B, 20(8), 447-469.

- Yueh, M. F., Taniguchi, K., Chen, S., Evans, R. M., Hammock, B. D., & Karin, M. (2014). The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proceedings of the National Academy of Sciences, 111(48), 17200-17205.

Melaleuca Alternifolia (Tea Tree) Leaf Oil

Other name: melaleuca alternifolia leaf oil; melaleuca alternifolia oil; tea tree leaf oil; tea tree essential oil

Function: Perfuming, Fragrance, Antioxidant

1. Definition Melaleuca Alternifolia (Tea Tree) Leaf Oil:

Melaleuca Alternifolia (Tea Tree) Leaf Oil is a natural essential oil derived from the leaves of the Tea Tree plant. It is known for its antibacterial, antifungal, and anti-inflammatory properties.

2. Use:

Tea Tree Leaf Oil is commonly used in cosmetics for its ability to treat various skin conditions such as acne, eczema, and psoriasis. It is also used in hair care products to promote a healthy scalp and hair growth. Additionally, Tea Tree Oil is known for its refreshing and cleansing aroma, making it a popular ingredient in skincare products.

3. Usage Melaleuca Alternifolia (Tea Tree) Leaf Oil:

When using Tea Tree Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin when used in high concentrations. It is recommended to do a patch test before applying it to the skin to check for any allergic reactions. Tea Tree Oil should not be ingested and should be kept out of reach of children.

4. References:

- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

- Hammer, K. A., Carson, C. F., & Riley, T. V. (2012). Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. Journal of Applied Microbiology, 95(4), 853-860.

- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

Lecithin

Other name: phosphatidylcholine; Lecithin; Lecithins; Soy Lecithin

Function: Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.