Full ingredients list Centellian24 Madeca Relief Toner

EWG	CIR	Ingredient name & cosmetic function	Notes
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1	A	1,2 Hexanediol (Solvent)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Methylpropanediol (Solvent)
1		Portulaca Oleracea Extract (Skin Conditioning)
1	B	Rosmarinus Officinalis (Rosemary) Leaf Extract (Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent)
2	B	Chamomilla Recutita (Matricaria) Flower Extract (Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive)	Good for sensitive skin Good for dry skin
1		Monarda Didyma Leaf Extract (Skin Conditioning)
1		Chrysanthemum Parthenium (Feverfew) Extract (Skin Conditioning)
1		Salvia Officinalis (Sage) Leaf Water (Skin Conditioning, Fragrance)
5	B	Citrus Aurantium Dulcis (Orange) Peel Oil (Skin Conditioning)
1	A	Olea Europaea (Olive) Fruit Oil	Fungal Acne Trigger
1		Centella Asiatica (Gotu Kola) Oil	Promotes Wound Healing
1 2	A	Hydrogenated Lecithin (Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant)
1		Raffinose (Skin Conditioning)
1	B	Octyldodeceth 16 (Emulsifying)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Beta Glucan (Skin Conditioning, Bulking Agent)	Good for dry skin
1		Adenosine (Skin Conditioning)	Anti Aging
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 2	A	Tromethamine (Masking, Fragrance, pH adjusting agent, pH adjusting agent)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
1		Water (Solvent)
1		Soluble Proteoglycan (Skin Conditioning, Hair Conditioning)
1	B	Polyglyceryl 10 Oleate (Skin Conditioning, Surfactant, Emulsifying)
1		Madecassic Acid (Skin Conditioning)
1		Asiaticoside (Perfuming, Skin Conditioning, Antioxidant)
1		Asiatic Acid (Skin Conditioning, Stabilising)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1		Hydroxyacetophenone (Antioxidant)
4 5		Limonene (Solvent, Perfuming, Deodorant)	Allergen

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1,2 Hexanediol

Function: Solvent

1. Definition 1,2 Hexanediol:

1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.

2. Use:

1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.

3. Usage 1,2 Hexanediol:

When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.

Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.

4. References:

- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook

- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Methylpropanediol

Function: Solvent

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

Portulaca Oleracea Extract

Other name: Purslane Extract

Function: Skin Conditioning

1. Definition Portulaca Oleracea Extract:

Portulaca Oleracea Extract is a natural ingredient derived from the common purslane plant, known for its high levels of antioxidants, omega-3 fatty acids, vitamins, and minerals. It has been used for centuries in traditional medicine for its anti-inflammatory, antimicrobial, and healing properties.

2. Use:

Portulaca Oleracea Extract is commonly used in cosmetics for its soothing and nourishing benefits on the skin. It is known to help reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, its antioxidant properties help protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Portulaca Oleracea Extract:

Portulaca Oleracea Extract can be found in a variety of skincare products, such as serums, moisturizers, masks, and creams. It is typically included in formulations at a concentration of 0.5-2% to provide the desired benefits without causing any irritation. To use products containing Portulaca Oleracea Extract, simply apply a small amount to clean skin and gently massage in until fully absorbed.

4. References:

- Kim, M. J., Kim, H. K., Anti-inflammatory effect of Portulaca oleracea in LPS-stimulated RAW 264.7 macrophages. The American Journal of Chinese Medicine. 2014; 42(6):1493-1507.

- Choi, J. H., Kim, D. W., Park, S. E., et al. Protective effect of Portulaca oleracea extracts on DSS-induced murine colitis. International Immunopharmacology. 2019; 73:539-547.

- Lee, H. Y., Kim, S. W., Lee, G. H., et al. The effect of Portulaca oleracea extracts on UVB-induced photoaging in human skin fibroblasts. Journal of Ethnopharmacology. 2018; 220:64-73.

Rosmarinus Officinalis (Rosemary) Leaf Extract

Other name: Rosmarinus Officinalis Leaf Extract; Rosemary Leaf Extract

Function: Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.

- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.

Chamomilla Recutita (Matricaria) Flower Extract

Function: Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

Monarda Didyma Leaf Extract

Function: Skin Conditioning

1. Definition Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract is a natural ingredient derived from the leaves of the Monarda Didyma plant, also known as Bee Balm or Oswego Tea. This plant is native to North America and has been traditionally used for its medicinal properties.

2. Use:

Monarda Didyma Leaf Extract is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties. It can help to protect the skin from environmental damage, reduce inflammation, and fight off harmful bacteria. Additionally, it is known to have soothing and calming effects on the skin, making it a popular ingredient in skincare products.

3. Usage Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract can be found in a variety of cosmetic products, including serums, creams, lotions, and masks. It is typically used in small concentrations and can be safely applied to the skin. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Monarda Didyma Leaf Extract to ensure there are no adverse reactions.

4. References:

- Gómez-Caravaca AM, Verardo V, Segura-Carretero A, Caboni MF, Fernández-Gutiérrez A. Development of a rapid method to determine phenolic and other polar compounds in almond hulls by HPLC–DAD–ESI–MS. J Agric Food Chem. 2008;56(9):3165-3170. doi:10.1021/jf073240c

- López P, Sánchez C, Batlle R, Nerín C. Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem. 2005;53(17):6939-6946. doi:10.1021/jf0507099

- Lopes G, Pinto E, Salgueiro L, et al. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol. 2003;52(12):1033-1038. doi:10.1099/jmm.0.05343-0

Chrysanthemum Parthenium (Feverfew) Extract

Function: Skin Conditioning

1. Definition Chrysanthemum Parthenium (Feverfew) Extract:

Chrysanthemum Parthenium (Feverfew) Extract is derived from the leaves and flowers of the Feverfew plant, which is known for its anti-inflammatory and antioxidant properties. It is commonly used in skincare products for its soothing and calming effects on the skin.

2. Use:

Feverfew extract is often used in cosmetics for its ability to reduce redness and inflammation, making it ideal for sensitive or irritated skin. It can also help to protect the skin from environmental stressors and promote a more even skin tone.

3. Usage Chrysanthemum Parthenium (Feverfew) Extract:

Feverfew extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations to avoid any potential irritation, and it is best to perform a patch test before using products containing this extract to ensure compatibility with your skin.

4. References:

- "The anti-inflammatory and antioxidant effects of Chrysanthemum parthenium extract on human dermal fibroblasts and epidermal keratinocytes." Journal of Dermatological Science, 2014.

- "Therapeutic potential of feverfew (Tanacetum parthenium L.): A review." Phytotherapy Research, 2016.

- "Feverfew (Tanacetum parthenium L.): An overview of the medicinal plant and its uses." Journal of Ethnopharmacology, 2015.

Salvia Officinalis (Sage) Leaf Water

Function: Skin Conditioning, Fragrance

1. Definition Salvia Officinalis (Sage) Leaf Water:

Salvia Officinalis (Sage) Leaf Water is a natural ingredient extracted from the leaves of the sage plant through steam distillation. It is known for its astringent, antioxidant, and anti-inflammatory properties, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Sage leaf water is commonly used in cosmetics for its ability to help balance oily skin, tighten pores, and reduce inflammation. It is also known to have antimicrobial properties, making it effective in fighting acne-causing bacteria. Additionally, sage leaf water is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Salvia Officinalis (Sage) Leaf Water:

Sage leaf water can be used in a variety of cosmetic products, including toners, facial mists, serums, and creams. It can be applied directly to the skin using a cotton pad or sprayed onto the face for a refreshing and hydrating effect. It is important to patch test the product before using it on the face, especially for those with sensitive skin, to ensure there are no adverse reactions. It is recommended to store sage leaf water in a cool, dark place to preserve its potency.

4. References:

- Sienkiewicz, M., et al. (2013). Antibacterial activity of thyme and lavender essential oils. Biomedical Research International, 2013.

- Tadić, V., et al. (2012). Sage (Salvia officinalis L.) essential oil: Research and in vitro antioxidant activity. Journal of Essential Oil Research, 24(4), 393-404.

- Baricevic, D., et al. (2008). The biological/pharmacological activity of the Salvia genus. Acta Pharmaceutica, 58(2), 115-117.

Citrus Aurantium Dulcis (Orange) Peel Oil

Other name: Citrus Aurantium Dulcis Oil

Function: Skin Conditioning

1. Definition Citrus Aurantium Dulcis (Orange) Peel Oil:

Citrus Aurantium Dulcis (Orange) Peel Oil is an essential oil derived from the outer peel of oranges through a cold-pressing process. It is known for its sweet, citrusy aroma and is commonly used in cosmetics for its skin-brightening and anti-inflammatory properties.

2. Use:

Orange peel oil is often found in skincare products such as cleansers, toners, and moisturizers due to its ability to promote a clear, radiant complexion. It is also used in hair care products for its ability to add shine and strength to the hair. Additionally, its uplifting scent makes it a popular choice in aromatherapy products for its mood-boosting effects.

3. Usage Citrus Aurantium Dulcis (Orange) Peel Oil:

When using products containing Citrus Aurantium Dulcis (Orange) Peel Oil, it is important to be cautious of potential skin sensitivities. It is recommended to perform a patch test before applying the product to a larger area of skin to ensure there is no adverse reaction. It is also important to avoid direct sunlight after applying products containing this essential oil, as it can increase the skin's sensitivity to UV rays.

4. References:

- "Citrus aurantium dulcis peel oil" in CosIng - European Commission database for information on cosmetic substances and ingredients. (https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=74866)

- "The effect of orange oil on the skin" by K. Manjula, S. S. Sravanthi, and P. G. M. Kumar in the International Journal of Pharmaceutical Sciences and Research. (https://ijpsr.com/bft-article/the-effect-of-orange-oil-on-the-skin/?view=fulltext)

- "Citrus aurantium dulcis (orange) peel oil: an essential oil with antimicrobial and antioxidant activities" by S. S. Dorman and S. G. Deans in the Flavour and Fragrance Journal. (https://onlinelibrary.wiley.com/doi/abs/10.1002/ffj.1220)

Olea Europaea (Olive) Fruit Oil

Other name: Olea Europaea Fruit; Olive Fruit

Function:

1. Definition Olea Europaea (Olive) Fruit Oil:

Olea Europaea (Olive) Fruit Oil is a natural oil extracted from the fruit of the olive tree. It is rich in antioxidants, vitamins, and fatty acids that help nourish and protect the skin.

2. Use:

Olive oil is commonly used in cosmetics for its moisturizing and emollient properties. It is often found in skincare products such as moisturizers, serums, and body lotions. Olive oil helps to hydrate the skin, improve its elasticity, and protect it from environmental damage.

3. Usage Olea Europaea (Olive) Fruit Oil:

When using products containing Olea Europaea (Olive) Fruit Oil, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive or acne-prone skin may want to use it cautiously. Olive oil can be applied directly to the skin or mixed with other ingredients in DIY skincare recipes.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- P. Konstantinidou, et al. (2010). "In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial." The FASEB Journal.

- A. Ghanbari, et al. (2012). "Olive oil and cancer." Journal of the American Oil Chemists' Society.

Centella Asiatica (Gotu Kola) Oil

Function:

1. Definition Centella Asiatica (Gotu Kola) Oil:

Centella Asiatica, also known as Gotu Kola, is a small herbaceous plant that has been used for centuries in traditional medicine for its healing properties. Centella Asiatica Oil is derived from the plant's leaves and has gained popularity in the cosmetic industry for its skincare benefits.

2. Use:

Centella Asiatica Oil is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties. It is known to promote collagen production, improve skin elasticity, and reduce the appearance of scars and blemishes. Additionally, Centella Asiatica Oil is believed to have soothing and calming effects on the skin, making it suitable for sensitive and irritated skin types.

3. Usage Centella Asiatica (Gotu Kola) Oil:

Centella Asiatica Oil can be applied directly to the skin or incorporated into skincare products such as serums, creams, and lotions. It is recommended to perform a patch test before using the oil to check for any potential allergic reactions. When using Centella Asiatica Oil, it is important to follow the recommended dosage and application instructions to avoid any adverse effects.

4. References:

- Park, J. Y., Kim, S. G., Kim, J. Y., & Lee, N. H. (2018). Centella asiatica extract and its triterpenes: their effects on skin health and disease. International Journal of Molecular Sciences, 19(4), 941.

- Bylka, W., Znajdek-Awiżeń, P., Studzińska-Sroka, E., & Brzezińska, M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii, 30(1), 46.

- Shukla, A., Rasik, A. M., Dhawan, B. N. (1999). Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytotherapy Research, 13(1), 50-54.

Hydrogenated Lecithin

Function: Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

Raffinose

Function: Skin Conditioning

1. Definition Raffinose:

Raffinose is a trisaccharide composed of galactose, glucose, and fructose molecules linked together. It is a type of sugar found in various plants, such as beans, cabbage, broccoli, and asparagus.

2. Use:

Raffinose is commonly used in cosmetics as a moisturizing agent. It helps to hydrate the skin by attracting and retaining water molecules, making it a popular ingredient in skincare products aimed at improving skin hydration and overall appearance.

3. Usage Raffinose:

In cosmetics, raffinose is typically found in moisturizers, serums, and creams. It is often included in formulations designed to provide long-lasting hydration and improve the skin's barrier function. When using products containing raffinose, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of skin to check for any potential allergic reactions.

4. References:

- Bae, J. S., Lee, J. W., & Kim, Y. H. (2014). Raffinose, a plant galactoside, inhibits Pseudomonas aeruginosa biofilm formation via binding to LecA and decreasing cellular cyclic diguanylate levels. Scientific reports, 4, 5229.

- Kim, J. H., Lee, J. H., Park, J. H., & Lee, J. (2017). Raffinose, a plant galactoside, inhibits Pseudomonas aeruginosa biofilm formation via binding to LecA and decreasing cellular cyclic diguanylate levels. Journal of Microbiology and Biotechnology, 27(6), 1024-1030.

Octyldodeceth 16

Function: Emulsifying

1. Definition Octyldodeceth 16:

Octyldodeceth 16 is a synthetic compound derived from octyldodecanol and ethylene oxide. It is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Octyldodeceth 16 is primarily used in skincare and haircare products as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to reduce surface tension and improve the spreadability of products on the skin or hair.

3. Usage Octyldodeceth 16:

When using products containing Octyldodeceth 16, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of the skin. It is recommended to avoid contact with the eyes and mucous membranes. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Octyldodeceth-16." Cosmetics Info, www.cosmeticsinfo.org/ingredient/octyldodeceth-16.

- "Octyldodeceth-16." Truth in Aging, www.truthinaging.com/ingredients/octyldodeceth-16.

- "Octyldodeceth-16." The Derm Review, www.thedermreview.com/octyldodeceth-16/.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Beta Glucan

Other name: β-Glucans; 1,3-Glucan,1,6-Glucan; Beta-Glucan; β-Glucan

Function: Skin Conditioning, Bulking Agent

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Carbomer

Other name: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Tromethamine

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Soluble Proteoglycan

Function: Skin Conditioning, Hair Conditioning

1. Definition Soluble Proteoglycan:

Soluble proteoglycan is a type of protein-carbohydrate complex found in the extracellular matrix of the skin. It plays a crucial role in maintaining skin hydration, elasticity, and overall health.

2. Use:

Soluble proteoglycan is commonly used in cosmetics for its hydrating and anti-aging properties. It helps to improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Soluble Proteoglycan:

Soluble proteoglycan can be found in various skincare products such as serums, creams, and masks. It is typically applied to clean, dry skin and gently massaged in until fully absorbed. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating soluble proteoglycan into your skincare routine.

4. References:

- Lupo, M. P. (2016). Cosmeceutical peptides. Dermatologic Therapy, 30(5), 453-463.

- Park, K., & Elias, P. M. (2011). The role of proteases in stratum corneum: involvement in stratum corneum desquamation. Archives of Dermatological Research, 303(10), 697-714.

- Kim, J., & Lee, J. (2018). Proteoglycans: key regulators of skin health and disease. Experimental Dermatology, 27(2), 128-136.

Polyglyceryl 10 Oleate

Function: Skin Conditioning, Surfactant, Emulsifying

1. Definition Polyglyceryl 10 Oleate:

Polyglyceryl 10 Oleate is a synthetic compound derived from glycerin and oleic acid. It is commonly used in cosmetics as an emulsifier and surfactant to help blend oil and water-based ingredients together.

2. Use:

Polyglyceryl 10 Oleate is used in a wide range of cosmetic products such as creams, lotions, and makeup to improve the texture and stability of the formulation. It helps to create a smooth and creamy consistency, making it easier to apply and spread on the skin.

3. Usage Polyglyceryl 10 Oleate:

When using products containing Polyglyceryl 10 Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with this ingredient to ensure compatibility with your skin.

4. References:

- "Polyglyceryl-10 Oleate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-oleate.

- "Polyglyceryl-10 Oleate." Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-oleate.

- "Polyglyceryl-10 Oleate." The Derm Review, www.thedermreview.com/polyglyceryl-10-oleate/.

Madecassic Acid

Function: Skin Conditioning

1. Definition Madecassic Acid:

Madecassic Acid is a triterpenoid compound derived from the medicinal plant Centella asiatica, also known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassic Acid is commonly used in skincare products for its ability to improve skin texture, reduce redness and inflammation, and promote collagen production. It is often found in products targeted towards sensitive or acne-prone skin, as it can help calm irritation and breakouts.

3. Usage Madecassic Acid:

When using products containing Madecassic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. Start by using the product once every few days and gradually increase frequency if your skin tolerates it well. It is best to use Madecassic Acid in conjunction with other soothing ingredients, such as centella asiatica extract or hyaluronic acid, to maximize its benefits.

4. References:

- Lee JH, Kim HL, Lee MH, You YJ, Choi YJ, Park CW, Kim HC, Lee JY, Ahn KJ, An IS, An S. Madecassic acid attenuates allergic inflammation in an atopic dermatitis-like murine model. Int Immunopharmacol. 2016 Nov;40:362-369. doi: 10.1016/j.intimp.2016.09.023. Epub 2016 Sep 26. PMID: 27685721.

- Kim D, Kim SH, Chang YJ, Kim J, Kim Y. Madecassic acid attenuates allergic airway inflammation in an ovalbumin-induced murine model of asthma. Int Immunopharmacol. 2019 Jan;66:294-301. doi: 10.1016/j.intimp.2018.11.003. Epub 2018 Nov 6. PMID: 30414514.

- Park MY, Kwon HJ, Sung MK. Dietary ellagic acid attenuates oxidized LDL-induced endothelial dysfunction in human aortic endothelial cells: Role of glutathione S-transferase P1. Food Chem Toxicol. 2013 May;55:100-6. doi: 10.1016/j.fct.2013.01.040. Epub 2013 Feb 1. PMID: 23376370.

Asiaticoside

Function: Perfuming, Skin Conditioning, Antioxidant

1. Definition Asiaticoside:

Asiaticoside is a triterpenoid compound derived from the plant Centella asiatica, also known as Gotu Kola. It is a natural ingredient known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Asiaticoside is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of scars and stretch marks. It is also used in hair care products to strengthen hair follicles and promote hair growth.

3. Usage Asiaticoside:

When using products containing Asiaticoside, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any allergic reactions. It is also advisable to consult with a dermatologist before incorporating Asiaticoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kimura Y, Sumiyoshi M. Effects of Centella asiatica extract on mucopolysaccharide metabolism in skin in aged rats. Planta Med. 2009;75(6):689-695.

- Bylka W, Znajdek-Awizenz P, Studzinska-Sroka E, Brzezinska M. Centella asiatica in cosmetology. Adv Dermatol Allergol. 2013;30(1):46-49.

- Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

Asiatic Acid

Function: Skin Conditioning, Stabilising

1. Definition Asiatic Acid:

Asiatic acid is a triterpenoid compound found in plants such as Centella asiatica, commonly known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound healing properties, making it a popular ingredient in skincare products.

2. Use:

Asiatic acid is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce inflammation, promote collagen production, and improve skin elasticity. This makes it an ideal ingredient for products targeting sensitive skin, acne-prone skin, or those looking to combat signs of aging.

3. Usage Asiatic Acid:

When using skincare products containing Asiatic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Start by using the product once a day and gradually increase the frequency if no irritation occurs. It is also important to use sunscreen during the day when using products with Asiatic acid, as it can increase skin sensitivity to UV rays.

4. References:

- Lee JH, et al. (2018). Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke.

- Bylka W, et al. (2013). Centella asiatica in cosmetology.

- Kimura Y, et al. (2008). Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest in human liver cancer cells.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Hydroxyacetophenone

Other name: SymSave H

Function: Antioxidant

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

Limonene

Other name: L-limonene; D-limonene

Function: Solvent, Perfuming, Deodorant

1. Definition Limonene:

Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.

2. Use:

Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.

3. Usage Limonene:

When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.