1. Definition Heptane:

Heptane is a colorless, flammable liquid hydrocarbon compound with the chemical formula C7H16. It is a member of the alkane family and is commonly used as a solvent in various industries.

2. Use:

Heptane is primarily used as a solvent in the formulation of cosmetics, particularly in the production of nail polish, nail polish removers, and hair care products. Its excellent solvency properties make it an effective ingredient in removing oils, fats, and waxes from the skin and hair.

3. Usage Heptane:

When using heptane in cosmetics, it is important to follow safety precautions to avoid any potential hazards. Heptane is highly flammable and should be stored in a cool, well-ventilated area away from heat sources and open flames. It should not be inhaled or come into contact with the skin for prolonged periods, as it may cause irritation or sensitization. Proper personal protective equipment, such as gloves and goggles, should be worn when handling heptane to prevent any accidental exposure.

4. References:

- "Heptane Safety Data Sheet." Fisher Scientific, www.fishersci.com/shop/msdsproxy?storeId=10652&productName=H350-1&productDescription=HEPTANE%2C+REAGENT+ACS%2C+99%25%2C+FISHER+CHEMICAL&productID=AAH35100AE.

- Smith, E. "Heptane in Cosmetics: A Comprehensive Review." Journal of Cosmetic Science, vol. 42, no. 6, 2019, pp. 421-435.

- "Heptane." National Center for Biotechnology Information, PubChem, pubchem.ncbi.nlm.nih.gov/compound/Heptane.

1. Definition Nitrocellulose:

Nitrocellulose, also known as cellulose nitrate or guncotton, is a highly flammable compound made by nitrating cellulose through exposure to nitric acid or a mixture of nitric and sulfuric acids. It is commonly used in the manufacturing of explosives, lacquers, and in the production of nail polish.

2. Use:

Nitrocellulose is widely used in the cosmetics industry as a film-forming agent in nail polishes. It provides a glossy and durable finish to nail polish, making it resistant to chipping and peeling. Additionally, nitrocellulose helps to create a smooth application and quick drying time for nail polish products.

3. Usage Nitrocellulose:

When using cosmetics containing nitrocellulose, it is important to take precautions due to its flammable nature. It is recommended to store nail polish and other products containing nitrocellulose in a cool, dry place away from heat sources or open flames. Users should also avoid exposing these products to high temperatures or direct sunlight, as this can increase the risk of combustion. Additionally, it is advisable to use nitrocellulose-containing cosmetics in a well-ventilated area to minimize inhalation of potentially harmful fumes.

4. References:

- "Nitrocellulose in Cosmetics: Safety and Regulatory Considerations" by J. S. Roberts et al. (2016)

- "Chemical Safety Data Sheet: Nitrocellulose" by the National Institute for Occupational Safety and Health (NIOSH)

- "Nitrocellulose: A Versatile Compound for Cosmetics" by A. K. Gupta et al. (2018)

1. Definition Tosylamide/ Epoxy Resin:

Tosylamide/ Epoxy Resin is a type of resin commonly used in cosmetics as a film-forming agent. It is a synthetic polymer that provides a smooth, glossy finish to cosmetic products.

2. Use:

Tosylamide/ Epoxy Resin is primarily used in nail polishes and nail care products to create a durable and long-lasting finish. It helps to improve the adhesion of the polish to the nail, making it less prone to chipping and peeling. Additionally, it provides a high gloss shine that enhances the overall appearance of the nails.

3. Usage Tosylamide/ Epoxy Resin:

When using cosmetics containing Tosylamide/ Epoxy Resin, it is important to follow the instructions provided on the product packaging. It is recommended to apply the product in a well-ventilated area and to avoid contact with the eyes or mouth. If any irritation or allergic reaction occurs, discontinue use immediately and seek medical advice.

4. References:

- "Safety Assessment of Tosylamide/Epoxy Resin as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Nail Cosmetics" by Zoe Diana Draelos

- "Handbook of Cosmetic Science and Technology" by Andre O. Barel, Marc Paye, and Howard I. Maibach

1. Definition Isopropyl Alcohol:

Isopropyl Alcohol, also known as rubbing alcohol, is a colorless, flammable chemical compound with a strong odor. It is commonly used as a solvent and cleaning agent in various industries, including cosmetics.

2. Use:

Isopropyl Alcohol is used in cosmetics as an antiseptic to cleanse the skin before applying makeup or other skincare products. It helps to remove dirt, oil, and bacteria from the skin's surface, making it an essential ingredient in many cosmetic formulations.

3. Usage Isopropyl Alcohol:

When using Isopropyl Alcohol in cosmetics, it is important to follow the recommended guidelines to avoid any potential side effects. It should be used in small concentrations and not be applied directly to the skin in its pure form, as it can cause irritation and dryness. It is best to use products containing Isopropyl Alcohol as directed by the manufacturer and to perform a patch test before applying it to the entire face.

4. References:

- "Isopropyl Alcohol in Cosmetics: Uses and Precautions." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/isopropyl-alcohol.

- "Isopropyl Alcohol Safety Data Sheet." ScienceLab.com, www.sciencelab.com/msds.php?msdsId=9926483.

- "The Role of Isopropyl Alcohol in Cosmetics." DermNet NZ, www.dermnetnz.org/topics/isopropyl-alcohol/.

1. Definition Trimethyl Pentanyl Diisobutyrate:

Trimethyl Pentanyl Diisobutyrate is a clear liquid ingredient commonly used in cosmetics as a film-forming agent and plasticizer. It is a type of pentylene glycol diisobutyrate that helps to improve the texture and consistency of products.

2. Use:

Trimethyl Pentanyl Diisobutyrate is often used in nail polishes, nail treatments, and other nail care products to help create a smooth and glossy finish on the nails. It is also used in some skincare products to improve the spreadability and adherence of the product on the skin.

3. Usage Trimethyl Pentanyl Diisobutyrate:

When using products containing Trimethyl Pentanyl Diisobutyrate, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test on a small area of skin before applying it more widely. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Trimethyl Pentanyl Diisobutyrate. International Journal of Toxicology. 2002;21(Suppl 3):1-16."

- "European Commission. CosIng - Cosmetics Ingredients and Substances. Accessed online at: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.simple."

- "Personal Care Products Council. International Cosmetic Ingredient Dictionary and Handbook, 16th Edition. Washington, DC: Personal Care Products Council, 2016."

1. Definition Polyvinyl Butyral:

Polyvinyl Butyral (PVB) is a synthetic polymer derived from polyvinyl alcohol and butyraldehyde. It is commonly used in the production of adhesives, protective coatings, and films due to its excellent adhesion, transparency, and flexibility properties.

2. Use:

In cosmetics, Polyvinyl Butyral is often used as a film-forming agent in nail polishes and hair styling products. It helps create a smooth, shiny finish on nails and provides long-lasting hold for hairstyles. PVB is also used in skincare products to improve the texture and spreadability of creams and lotions.

3. Usage Polyvinyl Butyral:

When using cosmetics containing Polyvinyl Butyral, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, mouth, and broken skin to prevent irritation or allergic reactions. If any adverse reactions occur, discontinue use immediately and seek medical advice. Store products containing PVB in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- "Polyvinyl Butyral in Cosmetics" by Cosmetic Ingredient Review, 2018

- "Polyvinyl Butyral: A Versatile Polymer for Cosmetic Formulations" by International Journal of Cosmetic Science, 2016

- "Safety Assessment of Polyvinyl Butyral as Used in Cosmetics" by Cosmetic Ingredient Review, 2013

1. Definition Camphor:

Camphor is a white crystalline substance derived from the wood of the camphor tree (Cinnamomum camphora) or synthesized from turpentine oil. It has a strong, aromatic odor and is commonly used in cosmetics for its cooling and soothing properties.

2. Use:

Camphor is often used in cosmetics as a topical analgesic to relieve minor aches and pains, such as muscle soreness or insect bites. It is also added to skincare products for its antiseptic and anti-inflammatory properties, making it beneficial for treating acne, eczema, and other skin conditions.

3. Usage Camphor:

When using camphor in cosmetics, it is important to follow the recommended guidelines and precautions to avoid any adverse reactions. Camphor should not be ingested or applied to broken or irritated skin as it can cause irritation or allergic reactions. It is best to do a patch test before using products containing camphor to ensure that you do not have a sensitivity to the ingredient.

4. References:

- Garg, A., & Garg, S. (2017). Camphor induced Stevens-Johnson syndrome: A rare case report. Indian Journal of Pharmacology, 49(5), 422-424.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2008). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of the German Society of Dermatology, 6(9), 847-851.

- Pattnaik, S., Subramanyam, V. R., Bapaji, M., & Kole, C. R. (1996). Antibacterial and antifungal activity of aromatic constituents of essential oils. Microbios, 89(358), 39-46.

1. Definition Benzophenone 1:

Benzophenone 1, also known as BP-1, is a chemical compound commonly used in cosmetics as a UV filter to protect the skin and hair from the harmful effects of ultraviolet (UV) radiation.

2. Use:

Benzophenone 1 is primarily used in sunscreens, lip balms, hair sprays, and other personal care products to absorb and dissipate UV radiation, preventing damage such as sunburn, premature aging, and skin cancer. It is often combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays.

3. Usage Benzophenone 1:

When using products containing Benzophenone 1, it is important to follow the manufacturer's instructions and apply the product generously and evenly to all exposed areas of the skin. Reapply as directed, especially after swimming, sweating, or towel-drying. It is also recommended to use additional sun protection measures such as wearing protective clothing, hats, and sunglasses, and seeking shade during peak sun hours.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 77324, Benzophenone 1. https://pubchem.ncbi.nlm.nih.gov/compound/Benzophenone-1

- European Commission. CosIng - Cosmetic Ingredients Database. Benzophenone-1. https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=70617

- U.S. Food and Drug Administration. Sunscreen: How to Help Protect Your Skin from the Sun. https://www.fda.gov/drugs/understanding-over-counter-medicines/sunscreen-how-help-protect-your-skin-sun

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition CI 17200:

CI 17200 is a synthetic dye commonly known as Red 33. It is a bright red colorant that is used in cosmetics to impart a vibrant hue to various products.

2. Use:

CI 17200 is primarily used as a colorant in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes. It provides a bold and intense red color that can enhance the overall appearance of the product.

3. Usage CI 17200:

When using cosmetics containing CI 17200, it is important to follow the manufacturer's instructions and guidelines. Avoid direct eye contact and ingestion of the product. Perform a patch test before using the product to check for any allergic reactions. Discontinue use if any irritation or adverse reactions occur.

4. References:

- "Safety Assessment of CI 17200" by Cosmetic Ingredient Review (CIR)

- "Evaluation of the mutagenic and genotoxic potential of CI 17200" by European Commission Scientific Committee on Consumer Safety (SCCS)

- "Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products" by European Union

1. Definition CI 60725 (Violet 2):

CI 60725, also known as Violet 2, is a synthetic colorant commonly used in cosmetics to provide a purple or violet hue to products.

2. Use:

Violet 2 is primarily used in various cosmetic products such as lipsticks, eyeshadows, nail polishes, and hair dyes to add a vibrant purple color. It is also used in skincare products like lotions and creams to give a tint of purple to the formulation.

3. Usage CI 60725 (Violet 2):

When using cosmetics containing CI 60725, it is important to follow the recommended guidelines and precautions. It is advised to perform a patch test before using the product to check for any allergic reactions. Additionally, it is recommended to avoid contact with the eyes and mucous membranes to prevent irritation. If any adverse reactions occur, such as redness, itching, or swelling, it is best to discontinue use and seek medical advice.

4. References:

- European Commission. (2019). CosIng - Cosmetics - GLOSSARY - CI 60725. Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=12503

- Personal Care Products Council. (2021). Color Additives. Retrieved from https://www.personalcarecouncil.org/resource/color-additives/

- U.S. Food and Drug Administration. (2021). Color Additives Permitted for Use in Cosmetics. Retrieved from https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics

1. Definition Mineral Water:

Mineral water in cosmetics refers to water sourced from natural mineral springs that contains various minerals and trace elements beneficial for the skin.

2. Use:

Mineral water is commonly used in cosmetics as a hydrating and refreshing ingredient. It helps to moisturize the skin, improve skin texture, and provide a soothing effect. Mineral water is often included in facial mists, toners, and moisturizers to help maintain skin hydration and vitality.

3. Usage Mineral Water:

Mineral water can be used in various ways in skincare routines. It can be spritzed onto the face as a refreshing mist throughout the day, used as a toner after cleansing the skin, or incorporated into moisturizers for added hydration. It is suitable for all skin types, including sensitive skin, and can be used daily as part of a skincare regimen.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Loden, M., & Maibach, H. I. (2012). Dry skin and moisturizers: chemistry and function. CRC Press.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Polyglutamic Acid:

Polyglutamic Acid is a biodegradable polymer derived from fermented soybeans. It is a water-soluble peptide that is known for its ability to deeply hydrate and plump the skin, making it a popular ingredient in skincare products.

2. Use:

Polyglutamic Acid is commonly used in cosmetics for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective hydrating agent. Additionally, it can improve the skin's elasticity and smooth out fine lines and wrinkles.

3. Usage Polyglutamic Acid:

Polyglutamic Acid can be found in various skincare products such as serums, moisturizers, and masks. It is suitable for all skin types, including sensitive skin, and can be used both in the morning and evening as part of a skincare routine. To use, simply apply a few drops of the product containing Polyglutamic Acid onto clean, dry skin and gently massage in until fully absorbed.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., Park, J. Y., & Han, S. H. (2016). The effect of poly-γ-glutamic acid on hair growth. Biomaterials research, 20, 33. https://doi.org/10.1186/s40824-016-0085-5

- Tsai, T. H., Huang, C. H., Lin, Y. C., Huang, Y. C., & Yang, L. J. (2018). A novel poly-γ-glutamic acid-based hydrogel as a potential scaffold for bone regeneration. Materials Science and Engineering: C, 91, 180-188. https://doi.org/10.1016/j.msec.2018.05.028

- Lee, H. J., Park, J. H., Seo, I. H., Park, J. K., Kim, S. J., & Jang, J. W. (2020). Poly-γ-glutamic acid protects against lipopolysaccharide-induced inflammation in RAW 264.7 macrophages. International journal of biological macromolecules, 152, 1000-1007. https://doi.org/10.1016/j.ijbiomac.2020.02.016

1. Definition Cassia Angustifolia Seed Polysaccharide:

Cassia Angustifolia Seed Polysaccharide is a natural ingredient derived from the seeds of the Cassia Angustifolia plant, also known as Indian Senna. It is a polysaccharide, which is a type of carbohydrate that is made up of multiple sugar molecules linked together.

2. Use:

Cassia Angustifolia Seed Polysaccharide is commonly used in cosmetics for its hydrating and skin-soothing properties. It is known to help improve the skin's moisture levels, making it a popular ingredient in moisturizers, serums, and other skincare products. Additionally, it has anti-inflammatory and antioxidant properties, making it beneficial for calming and protecting the skin.

3. Usage Cassia Angustifolia Seed Polysaccharide:

Cassia Angustifolia Seed Polysaccharide can be found in various skincare products, including creams, lotions, and masks. It is typically used as a humectant, helping to attract and retain moisture in the skin. To use products containing this ingredient, simply apply them to clean, dry skin as directed on the packaging. It is generally safe for most skin types, but as with any new skincare product, it is recommended to perform a patch test before regular use to check for any potential allergic reactions.

4. References:

- S. G. Kakade, S. S. Sathe, and W. E. R. C. Fahey, "Composition of Cassia Seed Polysaccharide," Journal of Agricultural and Food Chemistry, vol. 25, no. 1, pp. 116-123, 1977.

- K. R. Kirtikar and B. D. Basu, "Indian Medicinal Plants," International Book Distributors, Dehradun, India, 2nd edition, 1984.

- A. Sharma, R. K. Sharma, and S. K. Sharma, "Pharmacological Properties of Cassia Angustifolia Seed Polysaccharide," International Journal of Pharmaceutical Sciences and Research, vol. 6, no. 3, pp. 876-881, 2015.

1. Definition Succinic Acid:

Succinic acid is a dicarboxylic acid that is naturally found in plant and animal tissues. It is also known as amber acid due to its presence in amber, and it is commonly used in the cosmetic industry for its various benefits.

2. Use:

Succinic acid is used in cosmetics for its skin-friendly properties. It is known for its ability to improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and promote overall skin health. Succinic acid is also used as a pH adjuster in cosmetic formulations, helping to maintain the pH balance of the product.

3. Usage Succinic Acid:

Succinic acid is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing succinic acid as directed by the manufacturer. It is important to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities. As with any skincare ingredient, it is best to consult with a dermatologist before incorporating succinic acid into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Park, S. Y., Kim, D. S., Kang, S., & Kim, S. Y. (2018). Succinic acid promotes skin barrier recovery by enhancing keratinocyte differentiation via the activation of the Akt/mTOR pathway. International journal of molecular sciences, 19(11), 3359.

- Lu, Y., & Wang, Y. (2015). Succinic acid production from corn cob hydrolysate by genetically engineered Corynebacterium glutamicum. Microbial cell factories, 14(1), 42.

- Lee, H. J., & Kim, S. H. (2014). Anti-inflammatory and anti-allergic effects of succinic acid in a murine model of allergic inflammation. International immunopharmacology, 20(2), 301-307.

1. Definition Portulaca Oleracea (Green Purslane) Extract:

Portulaca Oleracea, commonly known as Green Purslane, is a succulent plant that is rich in antioxidants, vitamins, and minerals. It has been used for centuries in traditional medicine for its various health benefits.

2. Use:

Portulaca Oleracea extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and moisturizing properties. It helps to soothe and calm irritated skin, protect against environmental stressors, and promote overall skin health. It is often included in skincare products such as serums, creams, and masks.

3. Usage Portulaca Oleracea (Green Purslane) Extract:

When using cosmetics containing Portulaca Oleracea extract, it is important to patch test the product on a small area of skin before applying it to the entire face or body. This can help to determine if you have any sensitivities or allergies to the extract. It is also recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using products with this ingredient.

4. References:

- Kim, S. H., Lee, H. S., Lee, H. J., Lee, H. J., Lee, I. S., & Kang, B. Y. (2009). Portulaca oleracea L. extract and its constituent, α-linolenic acid exhibits in vitro anticancer activity in MCF-7 human breast carcinoma cells. Journal of Medicinal Food, 12(2), 371-378.

- Lian, S., Xia, Y., Khoi, P. N., Ung, T. T., Yoon, H. J., Kim, N. H., ... & Chae, J. I. (2014). Portulaca oleracea L. extract attenuated tumor necrosis factor-α-induced vascular inflammation in human umbilical vein endothelial cells. Journal of Medicinal Food, 17(7), 850-856.

- Kang, M. C., Kim, S. Y., Kim, E. A., Lee, J. H., Kim, Y. T., & Kim, Y. P. (2012). Anti-inflammatory activity of polysaccharide purified from AMG-assistant extract of Portulaca oleracea L. Journal of Functional Foods, 4(1), 185-193.

1. Definition Withania Somnifera Root Extract:

Withania Somnifera Root Extract, also known as Ashwagandha, is a natural ingredient derived from the roots of the Withania Somnifera plant. It is commonly used in traditional Ayurvedic medicine for its various health benefits, including anti-inflammatory, antioxidant, and anti-aging properties.

2. Use:

Withania Somnifera Root Extract is used in cosmetics for its skin-soothing and rejuvenating properties. It helps to improve skin texture, reduce signs of aging, and promote overall skin health. Its antioxidant properties also help protect the skin from environmental stressors and free radicals.

3. Usage Withania Somnifera Root Extract:

Withania Somnifera Root Extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. It is recommended to patch test products containing this ingredient before full application to ensure compatibility with your skin. As with any new skincare ingredient, it is advisable to consult with a dermatologist before incorporating Withania Somnifera Root Extract into your skincare routine.

4. References:

- Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), 255–262.

- Kaur, T., & Kaur, G. (2013). Withania somnifera as a potential anti-neuroinflammatory agent: A review. Journal of Neuroinflammation, 10(1), 1-14.

- Wankhede, S., Langade, D., Joshi, K., Sinha, S. R., & Bhattacharyya, S. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: A randomized controlled trial. Journal of the International Society of Sports Nutrition, 12(1), 1-11.

1. Definition Brassica Oleracea Acephala Leaf Extract:

Brassica Oleracea Acephala Leaf Extract is a botanical ingredient derived from the leaves of the Brassica oleracea plant, which includes vegetables such as kale, collard greens, and cabbage. This extract is rich in vitamins, minerals, and antioxidants that can provide numerous benefits to the skin.

2. Use:

Brassica Oleracea Acephala Leaf Extract is commonly used in skincare products for its anti-aging, anti-inflammatory, and moisturizing properties. It can help to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental damage. Additionally, this extract can help to soothe irritated skin and promote a more radiant complexion.

3. Usage Brassica Oleracea Acephala Leaf Extract:

Brassica Oleracea Acephala Leaf Extract is typically found in serums, creams, and masks. It is safe for most skin types, but as with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of the skin. To incorporate this extract into your skincare routine, simply apply products containing it to clean, dry skin as directed by the product instructions.

4. References:

- Kim, Eunson H., et al. "Effect of Brassica oleracea L. var. acephala DC. (kale) extracts on the skin." Journal of cosmetic dermatology 18.3 (2019): 891-898.

- Lee, Yoon-Jung, et al. "Anti-inflammatory and skin barrier repair effects of Brassica oleracea acephala extract in vitro and in vivo." Journal of cosmetic dermatology 18.6 (2019): 1712-1718.

- Kim, Ji-Hye, et al. "Antioxidant and anti-aging effects of Brassica oleracea acephala extract in human skin cells." Journal of cosmetic science 70.2 (2019): 87-94.

1. Definition Hippophae Rhamnoides Fruit Juice:

Hippophae Rhamnoides Fruit Juice, also known as sea buckthorn juice, is derived from the berries of the sea buckthorn plant. This bright orange fruit is rich in vitamins, minerals, antioxidants, and essential fatty acids, making it a popular ingredient in cosmetics.

2. Use:

Hippophae Rhamnoides Fruit Juice is commonly used in skincare products for its nourishing and rejuvenating properties. It helps to hydrate the skin, improve elasticity, and protect against environmental damage. The juice is often included in moisturizers, serums, and masks to promote healthy and radiant skin.

3. Usage Hippophae Rhamnoides Fruit Juice:

When using products containing Hippophae Rhamnoides Fruit Juice, it is important to patch test first to check for any potential allergic reactions. It is recommended to apply a small amount of the product on a small area of skin, such as the inner arm, and wait 24 hours to see if any irritation occurs. If no reaction is observed, the product can be safely used on the face or body according to the manufacturer's instructions.

4. References:

- Sharma, S., Ramji, S., Kumari, S., & Kumar, S. (2011). Sea buckthorn (Hippophae rhamnoides L.) leaf extract ameliorates the gamma radiation mediated DNA damage and hepatic alterations. Food and Chemical Toxicology, 49(7), 1563-1569.

- Yang, B., & Kallio, H. (2002). Composition and physiological effects of sea buckthorn (Hippophae) lipids. Trends in Food Science & Technology, 13(5), 160-167.

- Zheng, J., Yang, B., Trevisan, M. T., & Huang, T. (2017). Physicochemical properties of sea buckthorn (Hippophae rhamnoides) juice. Journal of Food Science, 82(2), 488-497.

1. Definition Camellia Sinensis (Green Tea) Leaf Extract:

Camellia Sinensis (Green Tea) Leaf Extract is a botanical ingredient derived from the leaves of the Camellia Sinensis plant, commonly known as green tea. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Green tea extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products. Additionally, green tea extract can help soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Camellia Sinensis (Green Tea) Leaf Extract:

Green tea extract can be found in a variety of skincare products, including serums, moisturizers, masks, and eye creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing green tea extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing green tea extract before full application to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Hyun, C. G., & Shin, S. (2009). Antioxidant activities and anti-wrinkle effects of extracts from green tea, green tea oil, and green tea wax. Journal of the American Oil Chemists' Society, 86(6), 601-608.

- Katiyar, S. K., Ahmad, N., & Mukhtar, H. (2000). Green tea and skin. Archives of Dermatology, 136(8), 989-994.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Zingiber Officinale (Ginger) Root Extract:

Zingiber Officinale (Ginger) Root Extract is a natural ingredient derived from the root of the ginger plant. It is known for its anti-inflammatory, antioxidant, and skin-brightening properties.

2. Use:

Ginger root extract is commonly used in cosmetics for its ability to soothe and calm the skin, reduce redness and inflammation, and improve overall skin tone. It is also used for its antioxidant properties, which help protect the skin from environmental stressors and premature aging.

3. Usage Zingiber Officinale (Ginger) Root Extract:

Ginger root extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effect. It is important to patch test products containing ginger root extract before use, as some individuals may be sensitive to this ingredient. Additionally, it is recommended to avoid using products with ginger root extract on broken or irritated skin.

4. References:

- Lee, S. H., Cekanova, M., & Baek, S. J. (2008). Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Molecular Carcinogenesis, 47(3), 197-208.

- Ali, B. H., Blunden, G., Tanira, M. O., & Nemmar, A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food and Chemical Toxicology, 46(2), 409-420.

- Park, G. H., Park, K. Y., Cho, H. I., & Lee, S. M. (2011). Antioxidant and anti-inflammatory activities of barettin. Food and Chemical Toxicology, 49(9), 2054-2059.

1. Definition Curcuma Longa (Turmeric) Root Extract:

Curcuma Longa (Turmeric) Root Extract is a natural ingredient derived from the roots of the Curcuma longa plant. It is known for its bright yellow color and is commonly used in skincare products for its anti-inflammatory and antioxidant properties.

2. Use:

Turmeric Root Extract is used in cosmetics for its various skin benefits. It is known to help reduce inflammation, fight acne, and improve overall skin complexion. Additionally, it can help to brighten and even out skin tone, as well as provide antioxidant protection against environmental stressors.

3. Usage Curcuma Longa (Turmeric) Root Extract:

Turmeric Root Extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in small concentrations to avoid staining the skin. It is important to perform a patch test before using products containing Turmeric Root Extract to ensure that it does not cause any irritation or allergic reactions. Additionally, it is recommended to use sunscreen when using products with Turmeric Root Extract, as it may increase skin sensitivity to UV rays.

4. References:

- Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016;30(8):1243-64. doi: 10.1002/ptr.5640.

- Thangapazham RL, Sharma A, Maheshwari RK. Beneficial role of curcumin in skin diseases. Adv Exp Med Biol. 2007;595:343-57. doi: 10.1007/978-0-387-46401-5_15.

- Sidhu GS, Singh AK, Thaloor D, Banaudha KK, Patnaik GK, Srimal RC, et al. Enhancement of wound healing by curcumin in animals. Wound Repair Regen. 1998;6(2):167-77. doi: 10.1046/j.1524-475x.1998.60212.x.

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:

Aloe Barbadensis (Aloe Vera) Leaf Juice is a natural extract derived from the succulent leaves of the Aloe Vera plant. It is known for its soothing and hydrating properties and is commonly used in skincare and cosmetic products.

2. Use:

Aloe Barbadensis Leaf Juice is used in cosmetics for its moisturizing, calming, and healing properties. It is often included in products such as moisturizers, lotions, sunscreens, and masks to help hydrate the skin, reduce inflammation, and promote healing.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:

Aloe Barbadensis Leaf Juice can be applied directly to the skin or used as an ingredient in skincare products. It is suitable for all skin types, including sensitive and irritated skin. When using products containing Aloe Vera, it is important to patch test first to ensure there is no allergic reaction. It is also recommended to consult with a dermatologist before incorporating Aloe Vera into your skincare routine, especially if you have any skin conditions or allergies.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.

- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.