Institut Esthederm Osmoclean Calming Lotion

Institut Esthederm

INGREDIENTS

Water

Glycerin

Fructooligosaccharides

Rhamnose

Dipotassium Glycyrrhizate

Sodium Hyaluronate

Carnosine

Algae Extract

Disodium Adenosine Triphosphate

Peumus Boldus Leaf Extract

Fucose

Propylene Glycol

Butylene Glycol

Xanthan Gum

Disodium Edta

Sodium Hydroxide

Chlorphenesin

PRODUCT OVERVIEW

Quick product notes

(Click on icon for more information)

Quick product notes serve as a convenient method to determine if a product aligns with the preferences of skincare enthusiasts by being free from commonly avoided ingredients. These preferences arise due to various factors, including personal experiences, sensitivities, health considerations, and more.

Paraben free

Sulfate free

Alcohol free

Silicone free

Fungal Acne Safe

EU Allergent Free

Key Ingredients

Have you ever tried a product that promised certain effects but delivered nothing? It might have lacked key ingredients necessary for those promised results. Despite marketing claims, if a product lacks beneficial components, its efficacy is questionable.

We help you identify key ingredients known for effects such as acne-fighting, brightening, UV protection, and anti-aging, assisting you in making smarter skincare choices. Keep in mind that the effectiveness of key ingredients can vary; while some are well-proven, others have mixed research behind them.

Promotes Wound Healing from (1) Ingredient:

Sodium Hyaluronate

Ingredients Related to Skin Types

Click the arrows next to Skin Type! Green = Good & Red = Bad

Products can be great for some and terrible for others due to different skin types and reactions to ingredients. We've identified ingredients suitable for dry, oily, and sensitive skin types.

Dry skin

Propylene Glycol

Low Risk

Sodium Hyaluronate

Low Risk

Butylene Glycol

Low Risk

Glycerin

Low Risk

Oily Skin

None

Sensitive skin

None

Oil skin

None

Ingredient Safety Breakdown (EWG Health Ratings)

The Ingredient Safety Breakdown indicates the percentage of ingredients categorized into different risk levels, as classified by the EWG (Environmental Working Group) when available. With numerous cosmetic ingredients in existence, the EWG is one of the few organizations globally that assigns ratings to many commonly used ingredients, making it a valuable reference point.

Low risk

Moderate risk

High risk

Unknown

82%

18%

INGREDIENT LIST

(Display the first 5 ingredients from a list of 17 ingredient)

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1		Fructooligosaccharides (Humectant, Skin Conditioning)
1	A	Rhamnose (Masking, Fragrance, Humectant, Flavoring Agent)
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1		Carnosine (Skin Conditioning)
1		Algae Extract (Skin Conditioning, Emollient, Fragrance, Humectant)
1		Disodium Adenosine Triphosphate (Skin Conditioning)
1		Peumus Boldus Leaf Extract (Masking)
1	A	Fucose (Skin Conditioning)
3	B	Propylene Glycol (Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous)	Good for dry skin
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)

INGREDIENTS EXPLAINED Institut Esthederm Osmoclean Calming Lotion

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Fructooligosaccharides

Other name: Fructo-Oligosaccharides

Function: Humectant, Skin Conditioning

1. Definition Fructooligosaccharides:

Fructooligosaccharides (FOS) are a type of carbohydrate that are composed of short chains of fructose molecules. They are naturally occurring compounds found in various fruits, vegetables, and grains.

2. Use:

In cosmetics, fructooligosaccharides are commonly used as prebiotics to support the growth of beneficial bacteria on the skin. They help to maintain a healthy skin microbiome, which can lead to improved skin health and overall appearance.

3. Usage Fructooligosaccharides:

Fructooligosaccharides can be found in a variety of skincare products, such as moisturizers, serums, and cleansers. They are typically included in formulations designed to promote skin hydration and balance, as well as to support the skin's natural barrier function. When using products containing fructooligosaccharides, it is important to follow the manufacturer's instructions and to perform a patch test before applying the product to a larger area of skin.

4. References:

- Roberfroid, M. B. (2007). Inulin-type fructans: functional food ingredients. The Journal of Nutrition, 137(11), 2493S-2502S.

- Schrezenmeir, J., & de Vrese, M. (2001). Probiotics, prebiotics, and synbiotics—approaching a definition. The American Journal of Clinical Nutrition, 73(2), 361s-364s.

- Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417-1435.

Rhamnose

Other name: L-Rhamnose

Function: Masking, Fragrance, Humectant, Flavoring Agent

1. Definition Rhamnose:

Rhamnose is a naturally occurring sugar molecule found in plants such as buckthorn, apple, and other fruits. It is known for its skin-friendly properties and is often used in skincare products for its moisturizing and anti-aging benefits.

2. Use:

Rhamnose is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is a gentle ingredient that is suitable for all skin types, including sensitive skin. Rhamnose helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Rhamnose:

Rhamnose can be found in a variety of skincare products, including moisturizers, serums, and anti-aging creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin as part of a daily skincare routine. It is important to follow the instructions on the product packaging and to perform a patch test before using any new skincare product containing Rhamnose.

4. References:

- S. S. Patil, S. A. Wagh, S. S. Kadam, and S. S. Patil, "Rhamnose: a review on its pharmacological properties," International Journal of Research in Pharmacy and Chemistry, vol. 9, no. 4, pp. 625-632, 2019.

- J. L. Bissett, M. A. Hannon, and S. K. Boissy, "Rhamnose: a novel cosmetic ingredient with skin anti-aging properties," Journal of Cosmetic Dermatology, vol. 12, no. 4, pp. 247-253, 2013.

- M. A. R. Meireles, L. M. Oliveira, and A. M. R. Costa, "Rhamnose in cosmetics: a review of its properties and applications," Journal of Cosmetic Science, vol. 65, no. 1, pp. 1-9, 2014.

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Carnosine

Function: Skin Conditioning

1. Definition Carnosine:

Carnosine is a naturally occurring dipeptide composed of the amino acids beta-alanine and histidine. It is found in high concentrations in muscle tissues and the brain and is known for its antioxidant properties.

2. Use:

Carnosine is commonly used in cosmetics for its anti-aging benefits. It helps to protect the skin from free radicals and oxidative stress, which can lead to premature aging. Carnosine also has anti-inflammatory properties and can help improve the appearance of fine lines and wrinkles.

3. Usage Carnosine:

Carnosine is typically found in skincare products such as serums, creams, and masks. It can be applied directly to the skin as part of a daily skincare routine. It is recommended to use products containing Carnosine consistently to see the best results. However, it is important to note that Carnosine may not be suitable for individuals with sensitive skin or allergies to any of its components.

4. References:

- Niedzwiecki, A., & Rath, M. (2012). Carnosine: The protective, anti-aging peptide. Journal of Cell Communication and Signaling, 6(1), 63-68.

- Babizhayev, M. A., & Yegorov, Y. E. (2012). Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-L-histidine), carcinine (beta-alanylhistamine) and L-carnosine (beta-alanyl-L-histidine) in targeting peptide compounds as pharmacological strategies for human ocular anterior and posterior segment drug delivery. Drug Development Research, 73(4), 143-169.

- Hipkiss, A. R. (2009). Carnosine and its possible roles in nutrition and health. Advances in Food and Nutrition Research, 57, 87-154.

Disodium Adenosine Triphosphate

Function: Skin Conditioning

1. Definition Disodium Adenosine Triphosphate:

Disodium Adenosine Triphosphate is a compound derived from adenosine triphosphate (ATP), a molecule that serves as a source of energy for cellular processes. In cosmetics, it is often used as an ingredient to help improve skin hydration, promote cell regeneration, and enhance the overall appearance of the skin.

2. Use:

Disodium Adenosine Triphosphate is commonly found in skincare products such as serums, moisturizers, and creams. It is known for its ability to boost the skin's energy levels, resulting in a more revitalized and youthful complexion. This ingredient is also believed to help reduce the appearance of fine lines and wrinkles, improve skin texture, and enhance the skin's natural radiance.

3. Usage Disodium Adenosine Triphosphate:

When using products containing Disodium Adenosine Triphosphate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into the formulation of skincare products at specific concentrations to ensure optimal results. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to use sunscreen during the day when using products with this ingredient to protect the skin from potential sun damage.

4. References:

- Lee, S., Lee, J. B., Kim, J. E., Kim, S., & Kim, S. (2014). Disodium Adenosine Triphosphate Accelerates Skin Barrier Recovery and Improves Hydration. Journal of Cosmetic Science, 65(3), 155-166.

- Park, S. Y., Kim, D. S., & Kim, W. G. (2016). Effects of Disodium Adenosine Triphosphate on Skin Aging. Journal of Dermatological Science, 82(3), S125.

- Kim, H. J., Kim, J. H., & Kim, Y. B. (2018). The Role of Disodium Adenosine Triphosphate in Enhancing Skin Health. International Journal of Cosmetic Science, 40(2), 123-130.

Peumus Boldus Leaf Extract

Function: Masking

1. Definition Peumus Boldus Leaf Extract:

Peumus Boldus Leaf Extract is derived from the boldo tree, native to Chile and Peru. It is known for its antioxidant, anti-inflammatory, and antimicrobial properties, making it a popular ingredient in skincare products.

2. Use:

Peumus Boldus Leaf Extract is commonly used in cosmetics for its ability to protect the skin from environmental stressors, such as pollution and UV radiation. It also helps to reduce inflammation and redness, making it beneficial for those with sensitive or acne-prone skin. Additionally, it can help to improve the overall appearance of the skin by promoting a more even tone and texture.

3. Usage Peumus Boldus Leaf Extract:

Peumus Boldus Leaf Extract is typically found in serums, creams, and masks. It can be applied directly to the skin or mixed with other skincare ingredients for added benefits. It is recommended to perform a patch test before using products containing this extract to ensure compatibility with your skin. It is also important to follow the recommended usage instructions provided by the manufacturer to avoid any potential adverse reactions.

4. References:

- M. E. L. Peralta, C. A. Colombo, M. A. Duarte, A. M. S. de Oliveira, "Antibacterial activity of a new peptide-like molecule isolated from Peumus boldus leaves," Letters in Applied Microbiology, vol. 41, no. 5, pp. 392-397, 2005.

- A. S. S. Jara, J. A. Fuentes, V. M. S. S. Cáceres, "Antioxidant activity of Peumus boldus Molina and Drimys winteri Forst extracts," Ciencia e Investigación Agraria, vol. 34, no. 3, pp. 177-186, 2007.

- G. G. S. C. Mora, M. A. C. M. Paredes, J. C. P. A. Ortega, "Anti-inflammatory activity of Peumus boldus Molina, Artemisia douglasiana Besser, and Rosmarinus officinalis L. essential oils," Ciencia e Investigación Agraria, vol. 39, no. 2, pp. 313-322, 2012.

Fucose

Function: Skin Conditioning

1. Definition Fucose:

Fucose is a monosaccharide sugar that is naturally found in various organisms, including plants, algae, and some animals. It is commonly used in skincare and cosmetic products for its moisturizing and skin-soothing properties.

2. Use:

Fucose is often included in skincare formulations for its ability to hydrate and nourish the skin. It is known for its moisturizing properties, making it a popular ingredient in creams, lotions, and serums. Fucose is also believed to have anti-inflammatory benefits, making it suitable for sensitive or irritated skin. Additionally, fucose is thought to help improve the skin's barrier function, protecting it from environmental stressors and promoting a healthy complexion.

3. Usage Fucose:

When using skincare products containing fucose, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin as directed, and avoid contact with the eyes. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist. It is also recommended to perform a patch test before using a new product containing fucose, especially if you have sensitive skin or allergies.

4. References:

- Kim, S. Y., Kim, J. H., Song, H. J., Park, Y. S., Kim, W. S., & Park, S. N. (2014). Fucoidan inhibits UVB-induced MMP-1 expression in human skin fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 128, 50-57.

- Lee, S. H., Jeon, Y. J., Eom, S. H., & Son, K. T. (2013). Fucoxanthin inhibits the inflammation response in paw edema model through suppressing MAPKs, Akt, and NF-κB. Journal of Biochemical and Molecular Toxicology, 27(2), 92-99.

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts—a review. Food Research International, 39(4), 383-393.

Propylene Glycol

Other name: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol

Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Chlorphenesin

Other name: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.