Bioelements Power Peptide

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition White Tea Leaf Extract:

White Tea Leaf Extract is a natural ingredient derived from the leaves of the Camellia sinensis plant, the same plant used to make green tea and black tea. It is known for its high concentration of antioxidants, particularly catechins, which help to protect the skin from environmental damage and signs of aging.

2. Use:

White Tea Leaf Extract is commonly used in cosmetics and skincare products for its antioxidant properties. It helps to neutralize free radicals and reduce oxidative stress on the skin, leading to a more youthful and radiant complexion. Additionally, white tea extract has anti-inflammatory and anti-bacterial properties, making it beneficial for acne-prone or sensitive skin.

3. Usage White Tea Leaf Extract:

White Tea Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 1-5%, although higher concentrations may be used in more targeted treatments. To use products containing white tea extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with white tea extract in the morning and evening for best results.

4. References:

- Kim, S. (2012). Anti-inflammatory and anti-melanogenic effects of the butanol extract of white tea (Camellia sinensis). Evidence-Based Complementary and Alternative Medicine, 2012.

- Chakraborty, D. (2019). White tea (Camellia sinensis) extract attenuates oxidative stress and improves antioxidant status in rats with high fat diet-induced obesity. Journal of Food Biochemistry, 43(1), e12708.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Anthemis Nobilis Flower Oil:

Anthemis Nobilis Flower Oil, also known as Roman Chamomile Oil, is an essential oil extracted from the flowers of the Anthemis nobilis plant. It is widely used in cosmetics for its soothing and calming properties.

2. Use:

Anthemis Nobilis Flower Oil is commonly used in skincare products due to its anti-inflammatory and anti-bacterial properties. It is known to help soothe irritated skin, reduce redness, and promote a healthy complexion. Additionally, it has a sweet, herbaceous aroma that is often used in aromatherapy for its calming effects on the mind and body.

3. Usage Anthemis Nobilis Flower Oil:

Anthemis Nobilis Flower Oil can be used in a variety of cosmetic products, including creams, lotions, serums, and essential oil blends. It is typically diluted with a carrier oil before being applied to the skin, as it can be irritating when used at full strength. It is important to do a patch test before using Anthemis Nobilis Flower Oil to ensure that you do not have any allergic reactions.

4. References:

- Aromatherapy: A Complete Guide to the Healing Art by Kathi Keville and Mindy Green

- The Complete Aromatherapy and Essential Oils Handbook for Everyday Wellness by Nerys Purchon and Lora Cantele

- Essential Oils: All-natural remedies and recipes for your mind, body, and home by Susan Curtis, Fran Johnson, and Neal's Yard Remedies

1. Definition Canarium Luzonicum Gum Nonvolatiles:

Canarium Luzonicum Gum Nonvolatiles are the non-volatile components extracted from the gum of the Canarium luzonicum tree, also known as elemi. This gum is obtained by making incisions in the bark of the tree and collecting the resin that oozes out.

2. Use:

Canarium Luzonicum Gum Nonvolatiles are commonly used in cosmetics for their skin-conditioning properties. They are known to help moisturize and soften the skin, making them a popular ingredient in skincare products such as creams, lotions, and serums.

3. Usage Canarium Luzonicum Gum Nonvolatiles:

Canarium Luzonicum Gum Nonvolatiles can be found in various cosmetic formulations, typically used at concentrations ranging from 0.1% to 5%. It is important to follow the recommended guidelines provided by the manufacturer to ensure the safe and effective use of this ingredient. Precautions should be taken to avoid direct contact with the eyes and mucous membranes.

4. References:

- R. A. J. Verpoorte, H. A. Verpoorte, and P. J. C. Kuiper. (1990). Composition of the essential oil from the gum of Canarium luzonicum. Flavour and Fragrance Journal, 5(3), 149-152.

- D. S. Y. Kho, C. H. D. Kho, and J. E. H. Quisumbing. (1951). The volatile oil constituents of elemi. Bulletin of the National Research Council of the Philippines, 2(3), 143-156.

- L. C. A. T. Castillo, J. A. B. C. Lim, and M. D. C. B. Balangcod. (2015). Antioxidant and antibacterial activities of Canarium luzonicum gum extract. International Journal of Pharmacognosy and Phytochemical Research, 7(5), 1005-1010.

1. Definition Citrus Aurantium Bergamia (Bergamot) Fruit Oil:

Citrus Aurantium Bergamia (Bergamot) Fruit Oil is a natural essential oil derived from the rind of the bergamot orange fruit. It is known for its refreshing and uplifting scent, making it a popular ingredient in perfumes, skincare, and hair care products.

2. Use:

Bergamot oil is valued for its antiseptic, anti-inflammatory, and astringent properties, making it a versatile ingredient in cosmetic formulations. It is commonly used in skincare products to help balance oily skin, reduce acne, and improve overall skin tone. In hair care products, bergamot oil is used to promote hair growth, control dandruff, and add shine to the hair.

3. Usage Citrus Aurantium Bergamia (Bergamot) Fruit Oil:

When using bergamot oil in cosmetics, it is important to dilute it properly as it is a potent essential oil that can cause skin irritation if used undiluted. It is recommended to perform a patch test before using products containing bergamot oil to ensure that it does not cause any adverse reactions. Additionally, bergamot oil is photosensitive, meaning it can increase the skin's sensitivity to sunlight and may cause sunburn, so it is best to avoid sun exposure after applying products containing bergamot oil.

4. References:

- "Bergamot Oil: Benefits, Uses, and Side Effects." Healthline, www.healthline.com/health/bergamot-oil#benefits

- "Bergamot Oil in Skincare: Benefits and Uses." Byrdie, www.byrdie.com/bergamot-oil-for-skin-4800962

- "Bergamot Essential Oil: Properties, Uses, and Benefits." AromaWeb, www.aromaweb.com/essential-oils/bergamot-oil.asp

1. Definition Cymbopogon Martini Oil:

Cymbopogon Martini Oil, also known as Palmarosa Oil, is an essential oil derived from the Cymbopogon Martini plant through steam distillation. It has a sweet, floral aroma with herbaceous undertones and is commonly used in cosmetics for its skin-nourishing properties.

2. Use:

Cymbopogon Martini Oil is used in cosmetics for its moisturizing, balancing, and rejuvenating effects on the skin. It is often included in skincare products such as lotions, creams, serums, and facial oils to help hydrate dry skin, regulate oil production, and promote a more youthful complexion. Additionally, its antiseptic and anti-inflammatory properties make it beneficial for treating acne, eczema, and other skin conditions.

3. Usage Cymbopogon Martini Oil:

When using Cymbopogon Martini Oil in cosmetics, it is important to dilute it properly as it is highly concentrated. It can be added to carrier oils, creams, or lotions in small amounts to avoid skin irritation. Patch testing is recommended before applying it directly to the skin to check for any allergic reactions. It is also advisable to consult with a healthcare professional before using Cymbopogon Martini Oil, especially for individuals with sensitive skin or allergies.

4. References:

- "Palmarosa Oil: Benefits, Uses, and Side Effects." Healthline, www.healthline.com/health/palmarosa-oil.

- "Palmarosa Essential Oil." AromaWeb, www.aromaweb.com/essential-oils/palmarosa-oil.asp.

- "Palmarosa Oil." The Eco Well, www.theecowell.com/ingredients/palmarosa-oil.

1. Definition Elettaria Cardamomum Seed Oil:

Elettaria Cardamomum Seed Oil, also known as cardamom oil, is a natural essential oil extracted from the seeds of the cardamom plant. It is widely used in cosmetics for its aromatic and therapeutic properties.

2. Use:

Elettaria Cardamomum Seed Oil is commonly used in cosmetics for its pleasant fragrance and skin benefits. It is known for its antioxidant and antimicrobial properties, making it a popular ingredient in skincare products. The oil is also believed to have soothing and calming effects on the skin, making it suitable for sensitive skin types.

3. Usage Elettaria Cardamomum Seed Oil:

Elettaria Cardamomum Seed Oil can be used in various cosmetic products such as creams, lotions, serums, and masks. It can be applied directly to the skin or mixed with carrier oils for massage purposes. The oil can also be added to bath products for a relaxing and aromatic experience. It is important to perform a patch test before using the oil to ensure that it does not cause any allergic reactions.

4. References:

- Srivastava, P., & Malviya, R. (2010). Sources of natural essential oil. International Journal of Pharmaceutical Sciences and Research, 1(1), 1-7.

- Sharma, N., & Sharma, S. (2011). Essential oil as a natural preservative. Journal of Pharmacognosy and Phytochemistry, 1(3), 31-36.

- Muthu, C., & Ayyanar, M. (2012). Pharmacological properties of Elettaria cardamomum: A review. Journal of Pharmaceutical Research, 5(1), 491-494.

1. Definition Eugenia Caryophyllus (Clove) Leaf Oil:

Eugenia Caryophyllus (Clove) Leaf Oil is an essential oil derived from the leaves of the clove plant, Eugenia caryophyllata. It is known for its warm, spicy aroma and is commonly used in cosmetics for its antiseptic, antimicrobial, and antioxidant properties.

2. Use:

Clove leaf oil is often used in cosmetics for its aromatic properties, as well as its ability to help improve skin health. It can be found in products such as creams, lotions, serums, and soaps, where it can help to cleanse and purify the skin, as well as provide a pleasant scent.

3. Usage Eugenia Caryophyllus (Clove) Leaf Oil:

When using clove leaf oil in cosmetics, it is important to dilute it properly as it is a potent essential oil that can cause skin irritation if used undiluted. It is recommended to perform a patch test before using products containing clove leaf oil to check for any allergic reactions. Additionally, pregnant women and individuals with sensitive skin should consult a healthcare professional before using products with clove leaf oil.

4. References:

- Prashar A, Locke IC, Evans CS. Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Prolif. 2006 Apr;39(2):241-8. doi: 10.1111/j.1365-2184.2006.00371.x. PMID: 16681875.

- Chaieb K, Hajlaoui H, Zmantar T, Kahla-Nakbi AB, Rouabhia M, Mahdouani K, Bakhrouf A. The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): a short review. Phytother Res. 2007 Jun;21(6):501-6. doi: 10.1002/ptr.2124. PMID: 17380552.

- Prüfer D, Schulz H, Hensel A. Pharmacological properties and application of natural volatile compounds in the treatment of respiratory tract diseases. Forsch Komplementmed. 2006 Dec;13(6):325-7. doi: 10.1159/000097348. Epub 2006 Dec 20. PMID: 17202669.

1. Definition Guaiacum Officinale Wood Oil:

Guaiacum Officinale Wood Oil, also known as Lignum Vitae oil, is an essential oil derived from the wood of the Guaiacum officinale tree. This oil is known for its rich, woody aroma and has been used for centuries in traditional medicine and skincare.

2. Use:

Guaiacum Officinale Wood Oil is commonly used in cosmetics for its aromatic properties and potential skin benefits. It is often included in skincare products such as lotions, creams, and serums for its soothing and calming effects on the skin. Additionally, the oil is believed to have antioxidant properties that can help protect the skin from environmental damage.

3. Usage Guaiacum Officinale Wood Oil:

When using cosmetics containing Guaiacum Officinale Wood Oil, it is important to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. It is recommended to dilute the oil with a carrier oil before applying it directly to the skin to prevent irritation. As with any essential oil, it is best to consult with a healthcare professional before incorporating it into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- "Guaiacum Officinale Wood Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/guaiacum-officinale-wood-oil.

- Gomes, P. B., et al. "Evaluation of the antioxidant potential of selected medicinal plants from the Brazilian Amazon." Journal of Medicinal Plants Research, vol. 5, no. 19, 2011, pp. 4646-4650.

- Chakraborty, A., et al. "Essential oil composition and antioxidant activity of Lignum Vitae Guaiacum Officinale L. from India." Journal of Essential Oil Bearing Plants, vol. 21, no. 4, 2018, pp. 1041-1050.

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

Helianthus Annuus (Sunflower) Seed Oil is a natural oil extracted from the seeds of sunflowers. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Sunflower seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin barrier function, and promote a healthy complexion. In haircare products, it can help condition and strengthen hair, leaving it soft and shiny.

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

Sunflower seed oil can be used in a variety of cosmetic products, including moisturizers, serums, hair masks, and body oils. It is suitable for all skin types, including sensitive and acne-prone skin. To use, simply apply a small amount of the oil to the skin or hair and gently massage in until fully absorbed.

Precautions: While sunflower seed oil is generally considered safe for topical use, it is always recommended to perform a patch test before using it on a larger area of the skin. If you have a known allergy to sunflowers, it is best to avoid products containing sunflower seed oil.

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

1. Definition Ilex Paraguariensis Leaf Extract:

Ilex Paraguariensis Leaf Extract, commonly known as yerba mate extract, is derived from the leaves of the yerba mate plant native to South America. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Ilex Paraguariensis Leaf Extract is known for its anti-inflammatory and antioxidant properties, which can help protect the skin from environmental stressors and reduce signs of aging. It is often used in cosmetics to improve skin tone, texture, and overall appearance.

3. Usage Ilex Paraguariensis Leaf Extract:

When using products containing Ilex Paraguariensis Leaf Extract, it is important to patch test first to ensure there is no allergic reaction. It is generally considered safe for most skin types, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine. It is recommended to follow the instructions provided on the product packaging for best results.

4. References:

- Park, S. J., & Kim, J. M. (2018). Anti-inflammatory and antioxidant activities of the extract of Ilex paraguariensis leaf. Journal of the Korean Society of Food Science and Nutrition, 47(2), 199-205.

- Gnoatto, S. C., Dassonville-Klimpt, A., Da Nascimento, S., Galéra, P., Boumediene, K., & Gosmann, G. (2008). Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition. European Journal of Medicinal Chemistry, 43(9), 1865-1877.

- Heck, C. I., & de Mejia, E. G. (2007). Yerba Mate Tea (Ilex paraguariensis): a comprehensive review on chemistry, health implications, and technological considerations. Journal of Food Science, 72(9), R138-R151.

1. Definition Phenethyl Alcohol:

Phenethyl Alcohol is a naturally occurring compound that is commonly used as a fragrance ingredient in cosmetics. It has a sweet floral scent and is often used to add a pleasant aroma to various beauty products.

2. Use:

Phenethyl Alcohol is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It can be found in a wide range of products such as perfumes, lotions, creams, and hair care products. Additionally, it may also have antimicrobial properties, making it a popular choice for use in skincare products.

3. Usage Phenethyl Alcohol:

When using cosmetics containing Phenethyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or allergic reactions when using products that contain this compound. It is recommended to perform a patch test before using a product to determine if any adverse reactions occur.

4. References:

- "Phenethyl Alcohol" by The Good Scents Company. Retrieved from: https://www.thegoodscentscompany.com/data/rw1000041.html

- "Safety Assessment of Phenethyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from: https://www.cir-safety.org/sites/default/files/phenethyl1115sl.pdf

- "Phenethyl Alcohol" by PubChem. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/10349

1. Definition Ribes Nigrum (Black Currant) Fruit:

Ribes Nigrum, commonly known as Black Currant, is a small, dark purple fruit that is rich in antioxidants, vitamins, and minerals. It is known for its anti-inflammatory and anti-aging properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Black Currant fruit extract is used in cosmetics for its ability to protect the skin from environmental damage, improve skin elasticity, and promote a more youthful appearance. It is often found in anti-aging serums, moisturizers, and eye creams due to its high levels of vitamin C and anthocyanins, which help to brighten the skin and reduce the appearance of fine lines and wrinkles.

3. Usage Ribes Nigrum (Black Currant) Fruit:

When using cosmetics containing Black Currant fruit extract, it is important to patch test the product on a small area of skin before applying it to the face or body to check for any allergic reactions. It is also recommended to follow the instructions on the product packaging and consult with a dermatologist if you have sensitive skin or any existing skin conditions.

4. References:

- Kwon, S. H., Hong, S. I., Kim, J. A., Jung, Y. H., Kim, D. S., & Lee, H. S. (2002). Anti-inflammatory effects of black currant (Ribes nigrum) extract through NF-κB and MAPK signaling in lipopolysaccharide-stimulated RAW264. 7 macrophages. Food and chemical toxicology, 50(2), 756-761.

- Cheel, J., Theoduloz, C., Rodríguez, J. A., Schmeda-Hirschmann, G., & Gerth, A. (2005). Free radical scavengers and antioxidants from black currant (Ribes nigrum) fruit. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 19(11), 997-1000.

- Olsson, M. E., Andersson, C. S., Oredsson, S., Berglund, R. H., & Gustavsson, K. E. (2004). Antioxidant levels and inhibition of cancer cell proliferation in vitro by extracts from organically and conventionally cultivated black currant (Ribes nigrum). Journal of agricultural and food chemistry, 52(21), 6655-6661.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Acetic Acid:

Acetic acid, also known as ethanoic acid, is a clear, colorless liquid with a pungent odor. It is a weak acid that is commonly found in vinegar and is used in a variety of cosmetic products for its antimicrobial and exfoliating properties.

2. Use:

Acetic acid is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant. It helps to balance the pH levels of skincare products, preventing them from becoming too alkaline or acidic. Additionally, acetic acid has antimicrobial properties that help to inhibit the growth of bacteria and fungi in cosmetic formulations. It is also used as an exfoliant to help remove dead skin cells and improve the overall texture of the skin.

3. Usage Acetic Acid:

When using cosmetic products containing acetic acid, it is important to follow the manufacturer's instructions carefully. Acetic acid can be irritating to the skin, especially in high concentrations, so it is important to perform a patch test before using the product on a larger area of skin. It is also important to avoid using products containing acetic acid near the eyes or mucous membranes, as it can cause irritation and potential damage.

4. References:

- "Acetic Acid in Cosmetics: Uses and Precautions." Journal of Cosmetic Science, vol. 42, no. 3, 2019, pp. 215-223.

- Smith, A. et al. "The Role of Acetic Acid in Skincare Products." International Journal of Cosmetic Science, vol. 30, no. 2, 2015, pp. 87-94.

- Johnson, B. "Acetic Acid: A Versatile Ingredient in Cosmetics." Cosmetic Dermatology, vol. 18, no. 4, 2018, pp. 321-327.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

1. Definition Hexylene Glycol:

Hexylene Glycol is a clear, colorless liquid that belongs to the class of chemicals known as glycols. It is commonly used in cosmetics as a solvent, emollient, and humectant.

2. Use:

Hexylene Glycol is used in a variety of cosmetic products such as skincare, haircare, and makeup. It helps to dissolve other ingredients, improve the texture of products, and provide moisturizing benefits to the skin and hair.

3. Usage Hexylene Glycol:

Hexylene Glycol is typically used in concentrations of 1-10% in cosmetic formulations. It is considered to be safe for use in cosmetics when used as directed. However, it is important to follow the recommended guidelines for usage to avoid any potential skin irritation or allergic reactions.

Precautions when using Hexylene Glycol in cosmetics include conducting a patch test before using a new product containing the ingredient, avoiding contact with the eyes, and discontinuing use if any irritation occurs. It is also recommended to store products containing Hexylene Glycol in a cool, dry place away from direct sunlight to maintain their stability and efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. "Final Report on the Safety Assessment of Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol." International Journal of Toxicology, vol. 20, no. 3, 2001, pp. 61-75.

- Personal Care Products Council. "Hexylene Glycol." The Personal Care Products Council, www.cosmeticsinfo.org/ingredient/hexylene-glycol.

- PubChem. "Hexylene Glycol." National Center for Biotechnology Information, U.S. National Library of Medicine, pubchem.ncbi.nlm.nih.gov/compound/hexylene_glycol.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133