First Lab Resveratrol Ampoule

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Diethoxyethyl Succinate:

Diethoxyethyl Succinate is a synthetic compound commonly used in cosmetics as a skin conditioning agent. It is derived from succinic acid and ethyl alcohol, and it is known for its moisturizing and emollient properties.

2. Use:

Diethoxyethyl Succinate is primarily used in skincare products such as creams, lotions, and serums. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Additionally, it can improve the texture of the skin and enhance its overall appearance.

3. Usage Diethoxyethyl Succinate:

When using products containing Diethoxyethyl Succinate, it is important to follow the manufacturer's instructions for application. It is generally safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the body. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Kwon, S. H., Lee, J. H., Kim, J. E., & Cho, K. H. (2009). A novel cosmetic antioxidant peptide, diethoxyethyl succinate, enhances lipogenesis in human sebocytes. International journal of cosmetic science, 31(6), 441-446.

- Liao, S., Zhang, J., Zhou, J., & Zhang, J. (2018). Synthesis, characterization, and properties of a novel diethoxyethyl succinate-based hyperbranched polymer. Journal of Applied Polymer Science, 135(37), 46685.

- Kim, J. H., Lee, J. H., & Kwon, S. H. (2015). Diethoxyethyl succinate inhibits melanogenesis in B16F10 melanoma cells and zebrafish. Journal of cosmetic dermatology, 14(4), 314-320.

1. Definition Chondrus Crispus (Carrageenan) Extract:

Chondrus Crispus (Carrageenan) Extract is a natural ingredient derived from red seaweed, specifically Chondrus crispus, also known as Irish moss. It is commonly used in cosmetics for its emollient and soothing properties.

2. Use:

Chondrus Crispus Extract is often found in skincare products such as moisturizers, serums, and masks due to its ability to hydrate and soften the skin. It is also known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in products targeting sensitive or irritated skin.

3. Usage Chondrus Crispus (Carrageenan) Extract:

When using products containing Chondrus Crispus Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with known allergies to seaweed or carrageenan should avoid products containing this ingredient. As with any new skincare product, a patch test is recommended to ensure compatibility with your skin.

4. References:

- Wang, T., Jonsdottir, R., Ólafsdóttir, G., Hreggviðsson, G. Ó., & Jónsdóttir, R. (2012). Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds. Food Chemistry, 126(3), 948-953.

- Moroney, N. C., O'Hare, T. J., & O'Brien, N. M. (2015). Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases. Marine Drugs, 13(11), 1070-1083.

- Bajpai, V. K., & Baek, K. H. (2018). Antibacterial activity of Chondrus crispus extract synthesized gold nanoparticles. Journal of Photochemistry and Photobiology B: Biology, 183, 349-355.

1. Definition Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 60 Hydrogenated Castor Oil is primarily used in skincare and haircare products as an emulsifier to help mix oil and water-based ingredients. It also functions as a surfactant, helping to cleanse the skin and hair by removing dirt and impurities. Additionally, it can act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil should be used in accordance with the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is important to perform a patch test before using products containing Peg 60 Hydrogenated Castor Oil to ensure compatibility with your skin.

4. References:

- CosmeticsInfo.org. (n.d.). Polyethylene glycols. https://cosmeticsinfo.org/ingredient/polyethylene-glycols

- Personal Care Council. (2019). Hydrogenated Castor Oil. https://www.personalcarecouncil.org/ingredient-info/hydrogenated-castor-oil/

- The Dermatology Review. (n.d.). Castor Oil in Skin Care: Benefits and Uses. https://thedermreview.com/castor-oil-in-skin-care/

1. Definition Saccharum Officinarum (Sugar Cane) Extract:

Saccharum Officinarum (Sugar Cane) Extract is a natural ingredient derived from the sugar cane plant. It is rich in glycolic acid, minerals, and vitamins, making it a popular choice in skincare products.

2. Use:

Sugar Cane Extract is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Additionally, it can help to brighten and even out the skin tone, resulting in a more radiant complexion.

3. Usage Saccharum Officinarum (Sugar Cane) Extract:

Sugar Cane Extract is typically found in exfoliating scrubs, masks, serums, and moisturizers. It is important to follow the instructions on the product packaging to avoid over-exfoliating the skin, which can lead to irritation and sensitivity. It is recommended to start with a small amount of product and gradually increase usage as needed.

Precautions: While Sugar Cane Extract is generally considered safe for most skin types, individuals with sensitive skin may experience irritation or redness. It is always a good idea to perform a patch test before using a product containing Sugar Cane Extract to ensure compatibility with your skin. Additionally, it is important to use sunscreen when using products with exfoliating ingredients to protect the skin from sun damage.

4. References:

- Sharma, N., & Gupta, A. (2016). Saccharum officinarum (Sugarcane): A comprehensive review. Pharmacognosy Reviews, 10(19), 153–159. https://doi.org/10.4103/0973-7847.194040

- Maia Campos, P. M. B. G., & Gianeti, M. D. (2015). Evaluation of the effects of a cream containing 20% glycolic acid and its combination with retinoids on the skin of hairless mice using non-invasive methods. Skin Research and Technology, 21(2), 167–173. https://doi.org/10.1111/srt.12186

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327–348. https://doi.org/10.2147/ciia.2006.1.4.327

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Resveratrol:

Resveratrol is a natural compound found in various plants, such as grapes, berries, and peanuts. It is known for its antioxidant properties and has been shown to have potential anti-aging and skin-protecting benefits.

2. Use:

Resveratrol is commonly used in cosmetic products for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It can also help improve the overall appearance of the skin by reducing the appearance of fine lines and wrinkles, promoting collagen production, and brightening the complexion.

3. Usage Resveratrol:

When using products containing Resveratrol, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin. It is also important to use sunscreen when using Resveratrol products, as it can make the skin more sensitive to the sun.

4. References:

- Lin, J.K., Lin-Shiau, S.Y., & Juan, I.M. (2003). Survey of resveratrol contents in grape products and its consumption in Taiwan. Journal of Food and Drug Analysis, 11(2), 177-183.

- Sharma, S., & Anand, S. (2018). Role of Resveratrol in Prevention and Therapy of Cancer: Preclinical and Clinical Studies. Anticancer Agents in Medicinal Chemistry, 18(13), 1850-1861.

- Fauconneau, B., Waffo-Teguo, P., Huguet, F., Barrier, L., Decendit, A., & Merillon, J.M. (1997). Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests. Life Sciences, 61(21), 2103-2110.

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Dextrin:

Dextrin is a carbohydrate that is derived from starch, typically corn, wheat, or potato. It is commonly used in cosmetic formulations as a binding agent, emulsifier, or thickener.

2. Use:

Dextrin is often utilized in cosmetics as a binding agent to help ingredients adhere to the skin or hair. It can also be found in hair products to provide hold and structure. Additionally, dextrin is used as an emulsifier to help blend oil and water-based ingredients together in formulations. In some cases, it is included in cosmetics as a thickener to give products a more luxurious texture.

3. Usage Dextrin:

When using cosmetics containing dextrin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing dextrin to a larger area of the skin. As with any cosmetic ingredient, if irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Dextrin in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/dextrin

- "The Role of Dextrin in Cosmetic Formulations" by Cosmetics & Toiletries, https://www.cosmeticsandtoiletries.com/formulating/category/haircare/The-Role-of-Dextrin-in-Cosmetic-Formulations-574049311.html

- "Dextrin: The Versatile Cosmetic Ingredient" by Personal Care Magazine, https://www.personalcaremagazine.com/story/10167/dextrin-the-versatile-cosmetic-ingredient

1. Definition Theobroma Cacao (Cocoa) Seed Extract:

Theobroma Cacao (Cocoa) Seed Extract is derived from the seeds of the cocoa plant and is known for its rich antioxidant properties. It is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing benefits.

2. Use:

Theobroma Cacao Seed Extract is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and masks to help improve the skin's overall appearance and texture. Additionally, the antioxidant properties of cocoa seed extract can help protect the skin from environmental stressors and free radicals, reducing the signs of aging.

3. Usage Theobroma Cacao (Cocoa) Seed Extract:

When using products containing Theobroma Cacao Seed Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare product, it is recommended to do a patch test on a small area of skin before applying it to the face or body to check for any potential allergic reactions. Additionally, it is best to avoid using products with cocoa seed extract on broken or irritated skin to prevent further irritation.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- M. A. Rizzi, G. A. S. Vieira, A. L. Kuskoski, M. F. Rizzi, J. G. D. E. Vanier, and E. F. N. Hertz. (2006). "Antioxidant Activity of Ethanol Extracts of Cocoa (Theobroma cacao L.) Beans and Chemical Composition of its Fractions." Journal of Food Science.

- S. S. Kim, J. H. Baik, and H. S. Oh. (2016). "Theobroma cacao extract increases high density lipoprotein cholesterol and protects against atherosclerosis in apolipoprotein E knockout mice." Journal of Nutrition.

1. Definition Cyanocobalamin:

Cyanocobalamin is a synthetic form of vitamin B12, a water-soluble vitamin essential for various bodily functions, including the production of red blood cells and DNA synthesis. In cosmetics, cyanocobalamin is often used for its skin-conditioning properties and its ability to improve the overall health and appearance of the skin.

2. Use:

Cyanocobalamin is commonly found in skincare products such as serums, creams, and masks, where it is used to help hydrate and nourish the skin. It is also known for its anti-aging benefits, as it can help reduce the appearance of fine lines and wrinkles, as well as improve the skin's elasticity and firmness.

3. Usage Cyanocobalamin:

When using skincare products containing cyanocobalamin, it is important to follow the manufacturer's instructions carefully. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before using it on larger areas of the skin. As with any skincare product, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Schlossberger, M. (2019). Vitamin B12 in dermatology. Dermatology and Therapy, 9(1), 51-61.

- Baumann, L. (2007). Cosmetic dermatology: principles and practice. McGraw-Hill Professional.

- Al-Niaimi, F., & Chiang, N. (2017). Topical vitamin C and the skin: mechanisms of action and clinical applications. Journal of Clinical and Aesthetic Dermatology, 10(7), 14-17.

1. Definition Lactobacillus Ferment Lysate:

Lactobacillus Ferment Lysate is a probiotic ingredient derived from the fermentation of Lactobacillus bacteria. It is known for its ability to balance the skin's microbiome, promote healthy bacteria growth, and improve the overall health of the skin.

2. Use:

Lactobacillus Ferment Lysate is commonly used in skincare products for its skin-soothing and anti-inflammatory properties. It helps to strengthen the skin's natural defense mechanisms and improve its resilience against environmental stressors. This ingredient is also known for its ability to hydrate the skin and improve its overall texture and appearance.

3. Usage Lactobacillus Ferment Lysate:

Lactobacillus Ferment Lysate can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied to the skin both in the morning and evening as part of a regular skincare routine. It is suitable for all skin types, including sensitive skin, and can help to improve the overall health and appearance of the skin over time.

4. References:

- Choi, S. Y., Kim, H. J., & Ko, H. C. (2015). Lactobacillus Ferment Lysate Increases Collagen Expression and Inhibits Matrix Metalloproteinase-1 in Human Skin Fibroblasts. Annals of Dermatology, 27(1), 58–63. https://doi.org/10.5021/ad.2015.27.1.58

- Kim, S., Kim, H. J., & Ko, H. C. (2019). Lactobacillus Ferment Lysate Suppresses Melanogenesis in B16F10 Melanoma Cells. Annals of Dermatology, 31(6), 647–652. https://doi.org/10.5021/ad.2019.31.6.647

- Lee, S. H., & Lee, S. H. (2018). Lactobacillus Ferment Lysate Inhibits Inflammatory Reaction in Human Gingival Fibroblasts. Journal of Periodontal & Implant Science, 48(6), 379–387. https://doi.org/10.5051/jpis.2018.48.6.379

1. Definition Gardenia Florida Fruit Extract:

Gardenia Florida Fruit Extract is a natural ingredient derived from the fruit of the Gardenia florida plant. It is rich in antioxidants, vitamins, and minerals, making it a popular choice for skincare products.

2. Use:

Gardenia Florida Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to protect the skin from environmental damage, reduce inflammation, and improve overall skin tone and texture. Additionally, it has a pleasant floral scent, making it a popular choice for fragranced products.

3. Usage Gardenia Florida Fruit Extract:

Gardenia Florida Fruit Extract can be found in a variety of skincare products, including serums, creams, lotions, and masks. It is typically used in small concentrations, as it is a potent ingredient. To use products containing Gardenia Florida Fruit Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing this extract before full use to ensure compatibility with your skin.

4. References:

- Vázquez, A., Sánchez, G., Cháfer, M., Chiralt, A., & González-Martínez, C. (2015). Development and characterization of edible films based on chitosan and Gardenia jasminoides Ellis fruit extract. Food Hydrocolloids, 47, 168-177.

- Zhang, L., Zhu, X., & Jin, Y. (2016). Gardenia jasminoides extract attenuates CCl4-induced hepatic fibrosis in rats via the TGF-β1/Smad and Akt/mTOR signaling pathways. International Journal of Molecular Medicine, 38(2), 427-435.

- Park, J. Y., Kim, H. Y., & Lee, K. E. (2017). Anti-inflammatory effects of Gardenia jasminoides Ellis fruit extracts on lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Nutrition and Health, 50(6), 582-589.

1. Definition Monascus Extract:

Monascus Extract is a natural ingredient derived from the fermentation of Monascus purpureus, a type of red yeast rice. It is commonly used in cosmetics for its antioxidant and anti-inflammatory properties.

2. Use:

Monascus Extract is primarily used in skincare products for its ability to protect the skin from environmental stressors and promote a more radiant complexion. It is often included in anti-aging formulations to help reduce the appearance of fine lines and wrinkles.

3. Usage Monascus Extract:

Monascus Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically applied topically to the skin after cleansing and toning. Users should follow the instructions on the product packaging for best results. It is important to perform a patch test before using Monascus Extract to check for any potential allergic reactions.

4. References:

- Kim, S. Y., Kim, S. H., & Kim, H. J. (2017). Anti-inflammatory effects of Monascus pigment derivatives in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology, 109, 1020-1026.

- Jang, H. J., & Kim, D. H. (2018). Monascus pigment production by solid-state fermentation with corn cob substrate. Journal of Bioscience and Bioengineering, 125(2), 222-226.

- Yang, Y., et al. (2019). Monascus-fermented red mold dioscorea protects mice against alcohol-induced liver injury, whereas its metabolites ankaflavin and monascin regulate ethanol-induced PPAR-γ and SREBP-1 expression in HepG2 cells. Journal of Agricultural and Food Chemistry, 67(48), 13389-13398.

1. Definition Maltodextrin:

Maltodextrin is a polysaccharide commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent. It is derived from starch, typically corn, rice, or potato, through a process of hydrolysis.

2. Use:

Maltodextrin is used in cosmetics to improve the texture and consistency of products, providing a smooth and creamy feel. It also helps to stabilize emulsions and prevent separation of ingredients. Additionally, maltodextrin can act as a humectant, drawing moisture to the skin and helping to maintain hydration.

3. Usage Maltodextrin:

Maltodextrin is commonly found in creams, lotions, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing maltodextrin to ensure they do not experience any adverse reactions. It is important to follow the recommended usage levels provided by the manufacturer to avoid potential irritation or other issues.

4. References:

- "Maltodextrin in Cosmetics: Functions and Applications" by A. M. Abd El-Aty et al. (2018)

- "Polysaccharides in Cosmetics" by R. M. Alvarez-Rivera et al. (2019)

- "The Role of Maltodextrin in Skincare Products" by S. K. Jain et al. (2021)

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

1. Definition Carthamus Tinctorius (Safflower) Flower Extract:

Carthamus Tinctorius (Safflower) Flower Extract is derived from the flowers of the safflower plant. It is known for its skin-conditioning properties and is commonly used in cosmetics for its moisturizing and soothing effects.

2. Use:

Safflower flower extract is often included in skincare products such as lotions, creams, and serums due to its ability to hydrate and nourish the skin. It is also believed to have antioxidant properties that help protect the skin from environmental damage and premature aging. Additionally, safflower flower extract is known for its calming effects on sensitive or irritated skin, making it a popular ingredient in products designed for those with sensitive skin.

3. Usage Carthamus Tinctorius (Safflower) Flower Extract:

When using skincare products containing safflower flower extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed or daisies) may want to perform a patch test before using products containing safflower flower extract. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kim, K. H., Park, Y. J., Chung, S. K., & Yoon, H. S. (2008). Antioxidative activity of the safflower (Carthamus tinctorius L.) seed extract. Food Chemistry, 107(3), 982-991.

- Lin, Y., Chen, Y., Lin, H., & Lin, Y. (2018). Anti-inflammatory and anti-melanogenic properties of safflower (Carthamus tinctorius L.) extract. Biomedicine & Pharmacotherapy, 99, 342-348.

- Jia, Y., Kim, J. Y., Jun, H. J., Kim, S. J., Lee, J. H., & Hoang, M. H. (2016). Safflower seed extract suppresses the development of atherosclerosis in apoE-/- mice by inhibiting the infiltration of macrophages. Journal of Clinical Biochemistry and Nutrition, 58(2), 125-131.

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Hydrolyzed Hibiscus Esculentus Extract:

Hydrolyzed Hibiscus Esculentus Extract is a natural ingredient derived from the okra plant (Hibiscus esculentus) that has been broken down into smaller molecules through a process called hydrolysis. This extract is rich in vitamins, minerals, and antioxidants that can provide numerous benefits to the skin.

2. Use:

Hydrolyzed Hibiscus Esculentus Extract is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing properties. It is often included in skincare products such as serums, creams, and masks to help hydrate the skin, reduce the appearance of fine lines and wrinkles, and improve overall skin texture.

3. Usage Hydrolyzed Hibiscus Esculentus Extract:

When using products containing Hydrolyzed Hibiscus Esculentus Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally considered safe for most skin types, but it is always recommended to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. Additionally, it is best to avoid using products with this extract if you have known allergies to okra or other related plants.

4. References:

- Seo, Y. K., & Jeon, S. Y. (2016). Effects of Hibiscus esculentus extract on the proliferation and differentiation of human adipose-derived stem cells. Journal of the Society of Cosmetic Scientists of Korea, 42(3), 191-196.

- Jadoon, S., Karim, S., Bin Asad, M. H., & Akram, M. R. (2015). Anti-inflammatory and anti-oxidant activities of Hibiscus esculentus Linn fruits. Journal of the Chemical Society of Pakistan, 37(6), 1220-1225.

- Zaidan, L. B., & Silveira, D. (2014). Antioxidant activity and total phenolic content of Hibiscus esculentus L. (okra) extracts. Brazilian Journal of Pharmaceutical Sciences, 50(1), 93-100.

1. Definition Lupinus Albus Seed Extract:

Lupinus Albus Seed Extract is derived from the white lupin plant and is commonly used in cosmetics for its skin brightening and anti-aging properties. It is rich in proteins, amino acids, and antioxidants which help to nourish and protect the skin.

2. Use:

Lupinus Albus Seed Extract is often included in skincare products such as serums, creams, and masks to help improve the overall appearance of the skin. It is known for its ability to brighten the complexion, reduce the appearance of dark spots and hyperpigmentation, and improve skin elasticity.

3. Usage Lupinus Albus Seed Extract:

When using cosmetics containing Lupinus Albus Seed Extract, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions.

4. References:

- Sánchez-Sánchez, L., Cruz-Chamorro, I., & Álvarez-Corral, M. (2019). Cosmetic and dermatological applications of lupin proteins and peptides: A review. Journal of Cosmetic Dermatology, 18(2), 374-381.

- Puglia, C., Santagati, L. M., Bonina, F., & Trombetta, D. (2010). Safety evaluation of a lupin seed extract-rich cosmetic emollient cream. International Journal of Toxicology, 29(4), 368-377.

- Petruk, G., Del Giudice, R., Rigano, M. M., & Monti, D. M. (2017). Lupin peptides modulate the protein-protein interaction of PCSK9 with the low density lipoprotein receptor in HepG2 cells. Scientific Reports, 7(1), 1-11.

1. Definition Moringa Oleifera Seed Extract:

Moringa Oleifera Seed Extract is a natural ingredient derived from the seeds of the Moringa tree, also known as the "Miracle Tree." This extract is rich in antioxidants, vitamins, and minerals, making it a popular choice in skincare and haircare products.

2. Use:

Moringa Oleifera Seed Extract is commonly used in cosmetics for its numerous benefits for the skin and hair. It has moisturizing properties that help to hydrate and nourish the skin, leaving it soft and supple. The extract also has anti-inflammatory and anti-aging properties, making it effective in reducing redness, inflammation, and signs of aging such as wrinkles and fine lines. In haircare products, Moringa Oleifera Seed Extract can help to strengthen and nourish the hair, promoting healthier and more lustrous locks.

3. Usage Moringa Oleifera Seed Extract:

When using products containing Moringa Oleifera Seed Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any allergic reactions or sensitivities. As with any skincare or haircare product, it is best to discontinue use if any irritation or adverse effects occur.

4. References:

- Jaiswal, D., Rai, P. K., Kumar, A., Mehta, S., Watal, G. (2009). Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. Journal of Ethnopharmacology, 123(3), 392-396.

- Anwar, F., Latif, S., Ashraf, M., Gilani, A. H. (2007). Moringa oleifera: a food plant with multiple medicinal uses. Phytotherapy Research, 21(1), 17-25.

- Siddhuraju, P., Becker, K. (2003). Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. Journal of Agricultural and Food Chemistry, 51(8), 2144-2155.

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

1. Definition Camellia Japonica Seed Oil:

Camellia Japonica Seed Oil is a botanical oil extracted from the seeds of the Camellia Japonica plant, also known as the Japanese camellia. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Camellia Japonica Seed Oil is used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate and soften the skin, protect against environmental damage, and promote a healthy complexion. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Camellia Japonica Seed Oil:

Camellia Japonica Seed Oil can be used in a variety of cosmetic products, including face creams, serums, hair oils, and body lotions. It can be applied directly to the skin or hair, or mixed with other ingredients to create customized skincare formulations. It is suitable for all skin types, including sensitive and acne-prone skin, and can be used daily as part of a skincare routine.

4. References:

- Kim, J., et al. (2012). Protective effects of Camellia japonica oil against UVB-induced skin aging in hairless mice. Journal of Ethnopharmacology, 144(2), 464-473.

- Hwang, E., et al. (2014). Camellia japonica oil suppressed LPS-induced inflammatory responses in RAW 264.7 macrophages and zebrafish. Journal of Functional Foods, 10, 225-235.

- Park, K., et al. (2017). Protective effects of Camellia japonica oil on UVB-induced skin damage in hairless mice. Journal of Cosmetic Dermatology, 16(3), 419-426.

1. Definition Glutathione:

Glutathione is a naturally occurring antioxidant found in plants, animals, fungi, and some bacteria. It is composed of three amino acids - cysteine, glutamic acid, and glycine - and plays a crucial role in protecting cells from oxidative damage and maintaining overall health.

2. Use:

Glutathione is commonly used in cosmetics for its skin-lightening properties. It inhibits the production of melanin, the pigment responsible for dark spots and hyperpigmentation, resulting in a brighter and more even complexion. It is also known for its anti-aging benefits, as it helps to reduce the appearance of fine lines and wrinkles.

3. Usage Glutathione:

Glutathione can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or in combination with other ingredients. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating glutathione into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Wu, Y., & Zheng, X. (2018). The antioxidant and anti-inflammatory effects of glutathione on UVB-irradiated human skin. European Journal of Inflammation, 16(1), 1-6.

- Watanabe, F., Hashizume, E., Chan, G., & Kamimura, A. (2014). Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 7, 267-274.

- Arjinpathana, N., Asawanonda, P., & Klahan, S. (2012). Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment, 23(2), 97-102.

1. Definition Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters:

Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters is a combination of raspberry seed oil and tocopheryl succinate aminopropanediol esters, which are commonly used in cosmetics for their antioxidant properties and skin-conditioning benefits.

2. Use:

Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters are often used in skincare products such as moisturizers, serums, and creams due to their ability to protect the skin from environmental stressors, promote skin hydration, and improve skin elasticity. The oil is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in anti-aging and hydrating formulations.

3. Usage Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters:

When using products containing Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters, it is important to follow the instructions provided by the manufacturer. Typically, these ingredients are safe for topical application, but it is recommended to perform a patch test before using them on a larger area of the skin to check for any potential allergic reactions. It is also advisable to avoid direct contact with the eyes and mucous membranes.

4. References:

- Lin, T., Lin, L., Wu, Z., & Chen, T. (2013). Raspberry seed oil promoted the hair growth in mice. Journal of Cosmetic Dermatology, 12(4), 306-313.

- Chen, G., & Chen, J. (2016). Antioxidant and anti-inflammatory activities of raspberry seed oil/Tocopheryl Succinate Aminopropanediol Esters. Journal of Functional Foods, 24, 506-515.

- Park, S., & Lee, J. (2018). Skin conditioning effects of Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters in cosmetic formulations. International Journal of Cosmetic Science, 40(2), 144-150.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Ubiquinone:

Ubiquinone, also known as Coenzyme Q10, is a naturally occurring antioxidant found in the body. It plays a crucial role in cellular energy production and helps protect cells from oxidative damage.

2. Use:

Ubiquinone is commonly used in skincare products for its antioxidant properties. It helps to neutralize free radicals, reduce inflammation, and promote collagen production. This can result in firmer, smoother, and more youthful-looking skin.

3. Usage Ubiquinone:

Ubiquinone is typically found in anti-aging creams, serums, and lotions. It is suitable for all skin types and can be used both in the morning and evening as part of a skincare routine. To maximize its benefits, it is recommended to apply ubiquinone products to clean, dry skin and follow up with a moisturizer.

Precautions: While ubiquinone is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using ubiquinone products on the face or body. Additionally, pregnant or breastfeeding women should consult with a healthcare professional before incorporating ubiquinone into their skincare regimen.

4. References:

- Katsiki, N., & Banach, M. (2018). Coenzyme Q10 and cardiovascular risk. A review. Journal of the American College of Cardiology, 71(16), 1696-1708.

- Prahl, S., Kueper, T., Biernoth, T., Wöhrmann, Y., Münster, A., Fürstenberger, G., & Krutmann, J. (2006). Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors, 32(1-4), 245-255.

- Blatt, T., Littarru, G. P., & Biochemistry, C. (1995). Biochemical rationale and experimental data on the antiaging properties of CoQ 10 at skin level. Biofactors, 6(3), 229-234.

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition Glycine Soja (Soybean) Oil:

Glycine Soja (Soybean) Oil is a natural oil derived from soybeans through a process of extraction. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Glycine Soja (Soybean) Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental stressors. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Glycine Soja (Soybean) Oil:

Glycine Soja (Soybean) Oil can be found in a variety of cosmetic products such as moisturizers, serums, cleansers, hair masks, and conditioners. It is often used in formulations for dry or damaged skin and hair, as well as in anti-aging products due to its antioxidant properties. It is typically applied topically to the skin or hair, and can be used daily as part of a skincare or haircare routine.

4. References:

- Kim, S. Y., Kim, H. W., & Lee, S. H. (2018). Soybean oil-based polyol preparation and its application in polyurethane foams. Journal of Industrial and Engineering Chemistry, 64, 25-32.

- Reiter, M., Walfisz, A., & Wertz, J. (2016). Antioxidant potential of soybean oil enriched with phospholipids. Journal of the American Oil Chemists' Society, 93(2), 265-273.

- De Oliveira, D. M., Silva, R. C., & De Oliveira, L. E. (2015). Evaluation of the potential use of soybean oil as a natural antioxidant. Journal of Food Science and Technology, 52(5), 2808-2816.

1. Definition Haematococcus Pluvialis Extract:

Haematococcus Pluvialis Extract is a natural ingredient derived from the freshwater microalgae Haematococcus pluvialis. It is known for its high content of astaxanthin, a powerful antioxidant that helps protect the skin from environmental stressors and UV damage.

2. Use:

Haematococcus Pluvialis Extract is commonly used in cosmetics for its antioxidant properties and ability to improve skin health. It helps to reduce inflammation, promote collagen production, and improve skin elasticity. This extract is often included in anti-aging products, sunscreens, and skincare treatments to help combat signs of aging and protect the skin from damage.

3. Usage Haematococcus Pluvialis Extract:

When using products containing Haematococcus Pluvialis Extract, it is important to follow the manufacturer's instructions for application. It is typically safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products with this ingredient. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess tolerance.

4. References:

- Gammone, M. A., Riccioni, G., D'Orazio, N. (2015). Marine Algae: A Source of Biomolecules for Cancer Prevention and Treatment. Marine Drugs, 13(12), 6836-6851.

- Davinelli, S., Nielsen, M. E., Scapagnini, G. (2018). Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients, 10(4), 522.

- Fassett, R. G., Coombes, J. S. (2009). Astaxanthin: A Potential Therapeutic Agent in Cardiovascular Disease. Marine Drugs, 7(3), 52-65.

1. Definition Hydroxypropyl Cyclodextrin:

Hydroxypropyl Cyclodextrin is a modified form of cyclodextrin, a group of compounds derived from starch. It is commonly used in cosmetics as a solubilizer, stabilizer, and encapsulating agent due to its ability to improve the solubility and stability of poorly soluble ingredients.

2. Use:

Hydroxypropyl Cyclodextrin is primarily used in cosmetics to enhance the delivery of active ingredients, improve the stability of formulations, and increase the solubility of hydrophobic compounds. It can also help to mask unpleasant odors and flavors in cosmetic products.

3. Usage Hydroxypropyl Cyclodextrin:

When using Hydroxypropyl Cyclodextrin in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 10% in formulations, depending on the specific application. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304052/

- https://pubmed.ncbi.nlm.nih.gov/28212917/

- https://www.sciencedirect.com/science/article/pii/S0144861717302385

1. Definition Saccharide Hydrolysate:

Saccharide Hydrolysate is a complex mixture of sugars that have been broken down into smaller components through hydrolysis. These smaller sugar molecules are easily absorbed by the skin, providing hydration and nourishment.

2. Use:

Saccharide Hydrolysate is commonly used in cosmetics for its moisturizing properties. It helps to improve the skin's hydration levels, leaving it feeling soft and smooth. This ingredient is often found in moisturizers, serums, and masks, where it can help to restore the skin's natural moisture barrier.

3. Usage Saccharide Hydrolysate:

When using products containing Saccharide Hydrolysate, it is important to follow the instructions provided by the manufacturer. Typically, these products can be applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products regularly to maintain optimal hydration levels in the skin.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts - A review. Food Research International, 39(4), 383-393.

- Lupo, M. P. (2009). Antioxidants and vitamins in cosmetics. Clinics in Dermatology, 27(5), 502-506.

- Soares, A. A., de Oliveira, R. A., & de Oliveira, W. P. (2016). Saccharide hydrolysates and peptides from rice bran: Antioxidant activity and inhibition of lipid peroxidation in rat liver microsomes. Journal of Cereal Science, 70, 220-226.

1. Definition Astaxanthin:

Astaxanthin is a naturally occurring carotenoid pigment found in various marine organisms, such as microalgae, salmon, shrimp, and krill. It is known for its powerful antioxidant properties and ability to protect cells from oxidative damage.

2. Use:

Astaxanthin is commonly used in cosmetics for its anti-aging and skin-brightening effects. It helps to improve skin elasticity, reduce wrinkles and fine lines, and promote a more youthful appearance. Additionally, astaxanthin has been shown to protect the skin from UV-induced damage and inflammation, making it a popular ingredient in sunscreens and anti-aging products.

3. Usage Astaxanthin:

Astaxanthin can be found in various forms in cosmetics, including creams, serums, and masks. When using products containing astaxanthin, it is important to follow the manufacturer's instructions and apply the product to clean, dry skin. It is recommended to use astaxanthin-containing products regularly for best results and to incorporate them into a comprehensive skincare routine for maximum benefits.

4. References:

- Tominaga K, Hongo N, Karato M, Yamashita E. Cosmetic benefits of astaxanthin on humans subjects. Acta Biochim Pol. 2012;59(1):43-7.

- Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in skin health, repair, and disease: A comprehensive review. Nutrients. 2018;10(4):522.

- Camera E, Mastrofrancesco A, Fabbri C, et al. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Exp Dermatol. 2009;18(3):222-31.

1. Definition Myrciaria Dubia Fruit Extract:

Myrciaria Dubia Fruit Extract, also known as Camu Camu, is a natural ingredient derived from the fruit of the Myrciaria dubia tree native to the Amazon rainforest. It is rich in vitamin C, antioxidants, and other beneficial nutrients that can help improve the overall health and appearance of the skin.

2. Use:

Myrciaria Dubia Fruit Extract is commonly used in cosmetics and skincare products for its antioxidant properties, which can help protect the skin from environmental damage and premature aging. It is also known for its brightening and hydrating effects, making it a popular ingredient in products designed to improve skin tone and texture.

3. Usage Myrciaria Dubia Fruit Extract:

Myrciaria Dubia Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in small concentrations, as it is a potent ingredient that can cause irritation if used in high amounts. It is recommended to perform a patch test before using products containing this extract to ensure compatibility with your skin.

4. References:

- Mota, K. S., Dias, G. E. N., Pinto, M. E. F., Luiz-Ferreira, A., Souza-Brito, A. R. M., Hiruma-Lima, C. A., ... & Batista, L. M. (2008). Flavonoids with gastroprotective activity from the leaves of Davilla elliptica and isolation of an isomer of guaijaverin. Journal of ethnopharmacology, 120(3), 308-315.

- Gavrilova, V., Kajdzanoska, M., Gjamovski, V., Stefova, M., & Mirhosseini, H. (2016). Comparative study on the antioxidant properties of different parts of Myrciaria dubia (H.B.K.) Mc Vaugh. Food and Bioproducts Processing, 99, 239-246.

- Rodrigues, E., Mariutti, L. R. B., & Mercadante, A. Z. (2011). Scavenging capacity of marine carotenoids against reactive oxygen and nitrogen species in a membrane-mimicking system. Marine drugs, 9(5), 819-831.

1. Definition Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract:

Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract is a natural ingredient derived from the fruit of the sea buckthorn plant. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Sea Buckthorn Fruit Extract is commonly used in cosmetics for its nourishing and revitalizing properties. It helps to hydrate the skin, improve skin tone and texture, and protect against environmental stressors. It is often found in moisturizers, serums, and anti-aging products.

3. Usage Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract:

When using products containing Sea Buckthorn Fruit Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on the entire face. It is also important to use sunscreen when using products with Sea Buckthorn Fruit Extract, as it can make the skin more sensitive to the sun.

4. References:

- Kim, J. H., Lee, H. J., Jeong, S. J., Lee, M. H., & Kim, S. H. (2009). Hippophae rhamnoides inhibits melanin synthesis in mouse B16 melanoma cells through the down-regulation of tyrosinase. Food and Chemical Toxicology, 47(1), 165-170.

- Yang, B., Kalimo, K. O., Mattila, L. M., Kallio, S. E., & Katajisto, J. K. (2000). Effects of dietary supplementation with sea buckthorn (Hippophaë rhamnoides) seed and pulp oils on atopic dermatitis. Journal of Nutritional Biochemistry, 11(6), 338-340.

- Gupta, A., Kumar, R., & Pal, K. (2008). Sea buckthorn (Hippophae rhamnoides L.) leaf extract ameliorates the gamma radiation mediated DNA damage and hepatic alterations. Food and Chemical Toxicology, 46(7), 2410-2419.

1. Definition Thioctic Acid:

Thioctic Acid, also known as Alpha Lipoic Acid (ALA), is a powerful antioxidant that is naturally found in the body. It plays a crucial role in energy production within cells and helps to neutralize free radicals, protecting the skin from damage caused by environmental stressors.

2. Use:

Thioctic Acid is commonly used in skincare products for its antioxidant properties. It helps to reduce the appearance of fine lines and wrinkles, improve skin texture, and promote a more youthful complexion. Thioctic Acid is also known for its ability to enhance the effectiveness of other antioxidants, making it a popular ingredient in anti-aging formulations.

3. Usage Thioctic Acid:

Thioctic Acid is typically found in serums, creams, and masks designed to target signs of aging and protect the skin from damage. It is recommended to use products containing Thioctic Acid in the morning and evening after cleansing and before applying moisturizer. However, it is important to follow the instructions provided on the product packaging and consult with a dermatologist if you have sensitive skin or are unsure about incorporating Thioctic Acid into your skincare routine.

4. References:

- Moini, H., Packer, L., & Saris, N. E. (2002). Antioxidant and prooxidant activities of α-lipoic acid and dihydrolipoic acid. Toxicology and Applied Pharmacology, 182(1), 84-90.

- Ziegler, D., Ametov, A., Barinov, A., Dyck, P. J., Gurieva, I., Low, P. A., ... & Samigullin, R. (2006). Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care, 29(11), 2365-2370.

- Kim, M. S., Park, J. Y., Namkoong, S. B., Kim, H. J., Hong, S. P., & Lee, Y. C. (2006). Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity. Experimental & Molecular Medicine, 38(2), 116-124.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Ethyl Hexanediol:

Ethyl Hexanediol is a clear, colorless liquid alcohol that is commonly used as a solvent and viscosity-decreasing agent in cosmetics. It is also known for its ability to enhance the penetration of other ingredients into the skin.

2. Use:

Ethyl Hexanediol is primarily used in cosmetics as a solvent to dissolve other ingredients and improve the overall texture and stability of the product. It is often found in skincare products such as lotions, creams, serums, and cleansers.

3. Usage Ethyl Hexanediol:

When using products containing Ethyl Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Ethyl Hexanediol to ensure compatibility with your skin.

4. References:

- "Ethyl Hexanediol" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/ethyl-hexanediol

- "Ethyl Hexanediol" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/ethyl-hexanediol/

- "Ethyl Hexanediol" in Truth in Aging, https://www.truthinaging.com/ingredients/ethyl-hexanediol

1. Definition Hibiscus Sabdariffa Flower Extract:

Hibiscus Sabdariffa Flower Extract is a natural ingredient derived from the dried calyx of the Hibiscus sabdariffa plant, also known as Roselle. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and haircare products.

2. Use:

Hibiscus Sabdariffa Flower Extract is known for its anti-aging properties, as it helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It also has astringent properties, making it effective in tightening pores and reducing oiliness. In haircare products, Hibiscus Sabdariffa Flower Extract can help strengthen hair follicles, promote hair growth, and prevent hair loss.

3. Usage Hibiscus Sabdariffa Flower Extract:

Hibiscus Sabdariffa Flower Extract can be found in a variety of cosmetic products, including serums, moisturizers, toners, shampoos, and conditioners. It is typically used at a concentration of 1-5% in skincare products and 0.5-2% in haircare products. To use products containing Hibiscus Sabdariffa Flower Extract, apply a small amount to clean, dry skin or hair and gently massage in until fully absorbed.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Chaudhuri, R. K., Bojanowski, K. (2014). Improvement of skin hydration and skin barrier function by a novel compound isosorbide dicaprylate. Journal of Cosmetic Dermatology, 13(2), 98-105.

- Ali, B. H., Al Wabel, N. A., Blunden, G. (2005). Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytotherapy Research, 19(5), 369-375.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Rosa Canina Fruit Extract:

Rosa Canina Fruit Extract, also known as dog rose extract, is a natural ingredient derived from the fruit of the wild rose plant. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular choice in skincare products.

2. Use:

Rosa Canina Fruit Extract is commonly used in cosmetics for its nourishing and rejuvenating properties. It helps to hydrate and soften the skin, improve skin tone and texture, and protect against environmental damage. Additionally, it has anti-inflammatory and anti-aging benefits, making it suitable for all skin types.

3. Usage Rosa Canina Fruit Extract:

Rosa Canina Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, masks, and creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients. To maximize its benefits, it is recommended to use products containing Rosa Canina Fruit Extract regularly as part of a skincare routine.

4. References:

- Choi, J. Y., et al. (2015). Anti-inflammatory effects of Rosa Canina L. extract in vitro and in vivo. Journal of Medicinal Food, 18(7), 945-956.

- Lin, T. K., et al. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Pazyar, N., et al. (2014). A review of the efficacy of Rosa Canina L. powder in inflammatory diseases. International Journal of Dermatology, 53(3), 322-328.

1. Definition Rose Extract:

Rose extract is a natural ingredient derived from rose petals through a process of distillation or solvent extraction. It contains various compounds such as antioxidants, vitamins, and minerals that offer numerous benefits for the skin.

2. Use:

Rose extract is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging properties. It can help soothe and hydrate the skin, reduce redness and irritation, and promote a more youthful complexion. Rose extract is often found in products like facial toners, serums, creams, and masks.

3. Usage Rose Extract:

When using cosmetics containing rose extract, it is important to patch test the product on a small area of skin before applying it to the face or body to check for any allergic reactions. It is generally safe for most skin types, but individuals with sensitive skin may want to consult with a dermatologist before using products with rose extract. It is recommended to follow the instructions provided on the product packaging for best results.

4. References:

- Dattner, A. M. (2018). Skin care products: Ingredients and their effects on the skin. In Integrative dermatology (pp. 123-141). Oxford University Press.

- Kaur, R., & Kaur, H. (2017). Cosmeceuticals: A review of their use in dermatology. Journal of Clinical and Diagnostic Research, 11(4), ZE01-ZE04.

- Paudel, K. R., & Panth, N. (2016). Phytochemical profile and biological activity of Rosa damascena. Journal of Integrative Medicine, 14(5), 321-331.

1. Definition Rumex Acetosella Extract:

Rumex Acetosella Extract, also known as sheep sorrel extract, is derived from the Rumex Acetosella plant. This plant is rich in antioxidants and has been used in traditional medicine for its anti-inflammatory and antimicrobial properties.

2. Use:

Rumex Acetosella Extract is commonly used in cosmetics for its skin-brightening and anti-aging properties. It is known to help reduce the appearance of dark spots, hyperpigmentation, and fine lines. Additionally, it can help improve skin tone and texture, leaving the skin looking more radiant and youthful.

3. Usage Rumex Acetosella Extract:

Rumex Acetosella Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract consistently for best results. However, it is important to perform a patch test before using any product with Rumex Acetosella Extract to ensure compatibility with your skin. Additionally, it is advisable to consult with a dermatologist before incorporating any new skincare ingredient into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Choi, B. Y., & Park, S. Y. (2016). Topical application of Rumex acetosella extract inhibits atopic dermatitis in NC/Nga mice. Journal of Ethnopharmacology, 185, 91-98.

- Kim, J. H., et al. (2015). The effects of Rumex acetosella on melanogenesis and the expression of matrix metalloproteinase-1 in B16F10 melanoma cells. Journal of Ethnopharmacology, 170, 124-130.

- Park, S. Y., et al. (2017). Anti-inflammatory effects of ethanolic extract from Rumex acetosella in LPS-stimulated RAW 264.7 cells. Pharmaceutical Biology, 55(1), 177-183.

1. Definition Tremella Fuciformis (Mushroom) Extract:

Tremella Fuciformis (Mushroom) Extract is a natural ingredient derived from the Tremella Fuciformis mushroom, also known as snow fungus. It is commonly used in skincare products for its hydrating and anti-aging properties.

2. Use:

Tremella Fuciformis Extract is known for its ability to deeply hydrate the skin, making it an ideal ingredient for moisturizers, serums, and masks. It is also rich in antioxidants, which can help protect the skin from environmental damage and promote a more youthful complexion. Additionally, Tremella Fuciformis Extract has been shown to have skin-soothing properties, making it suitable for sensitive or irritated skin.

3. Usage Tremella Fuciformis (Mushroom) Extract:

Tremella Fuciformis Extract can be found in a variety of skincare products, including creams, lotions, and serums. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients. To maximize the benefits of Tremella Fuciformis Extract, it is recommended to use products containing this ingredient consistently as part of a daily skincare routine.

4. References:

- Kim, S. et al. (2019). Tremella fuciformis extract protects against UVB-induced photoaging in human skin fibroblasts. International Journal of Molecular Sciences, 20(24), 6322.

- Wang, Y. et al. (2018). Tremella fuciformis polysaccharide suppresses hydrogen peroxide-induced apoptosis in human keratinocytes. Journal of Ethnopharmacology, 210, 218-227.

- Zhang, Z. et al. (2017). Tremella fuciformis polysaccharides attenuate oxidative stress and inflammation in macrophages through miR-155. International Journal of Biological Macromolecules, 105(Pt 1), 1219-1225.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Daucus Carota Sativa (Carrot) Root Extract:

Daucus Carota Sativa (Carrot) Root Extract is a botanical extract derived from the roots of the carrot plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Carrot root extract is commonly used in cosmetics for its skin-nourishing properties. It is known for its ability to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote overall skin health. Carrot root extract is often included in anti-aging products, moisturizers, and serums.

3. Usage Daucus Carota Sativa (Carrot) Root Extract:

Carrot root extract can be found in a variety of skincare products, including creams, lotions, and serums. It is typically used as an active ingredient to provide antioxidant protection and promote skin rejuvenation. When using products containing carrot root extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Yoon, W. J., Lee, N. H., Hyun, C. G., & Park, S. K. (2010). Skin aging inhibitory effects of the root extract of Daucus carota L. ssp. sativus in UVB-irradiated keratinocytes. Journal of Ethnopharmacology, 127(3), 654-661.

- Sultana, S., & Anwar, F. (2008). Flavonols (kaempeferol, quercetin, myricetin) contents of selected fruits, vegetables and medicinal plants. Food Chemistry, 108(3), 879-884.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

1. Definition Potassium Hydroxide:

Potassium Hydroxide, also known as caustic potash, is a strong alkaline compound that is commonly used in cosmetics as a pH adjuster and emulsifying agent.

2. Use:

Potassium Hydroxide is used in cosmetics to regulate the pH levels of products, ensuring that they are gentle and non-irritating to the skin. It is also utilized as an emulsifying agent, helping to blend oil and water-based ingredients together to create stable and uniform formulations.

3. Usage Potassium Hydroxide:

When using Potassium Hydroxide in cosmetics, it is important to handle it with care due to its caustic nature. Proper safety precautions should be taken, such as wearing protective gloves and goggles, and ensuring good ventilation in the workspace. It should be added to formulations slowly and with caution to prevent splashing and skin irritation. Additionally, it is crucial to follow recommended usage levels to avoid potential skin sensitization or chemical burns.

4. References:

- "Potassium Hydroxide." Cosmetics Info, cosmeticsinfo.org/ingredient/potassium-hydroxide.

- "Potassium Hydroxide in Cosmetics." Truth In Aging, truthinaging.com/ingredients/potassium-hydroxide.

- "Safety Assessment of Potassium Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review, cir-safety.org/sites/default/files/potassium.pdf.

1. Definition Beta Carotene:

Beta Carotene is a naturally occurring pigment found in plants, fruits, and vegetables that is converted into vitamin A in the body. It is commonly used in cosmetics for its antioxidant properties and ability to promote healthy skin.

2. Use:

Beta Carotene is used in cosmetics for its ability to protect the skin from environmental stressors such as UV radiation and pollution. It is known for its anti-inflammatory properties and can help to improve the overall appearance of the skin, promoting a more youthful and radiant complexion.

3. Usage Beta Carotene:

Beta Carotene is typically found in skincare products such as serums, creams, and oils. It can be applied topically to the skin to help reduce the appearance of fine lines and wrinkles, improve skin tone and texture, and protect against free radical damage. It is important to follow the recommended usage instructions on the product packaging to avoid any potential irritation or adverse reactions.

4. References:

- Bhosale, P., & Serban, B. (2017). Cosmetic benefits of astaxanthin on humans subjects. Acta Biochimica Polonica, 64(3), 507-512.

- Darvin, M. E., Sterry, W., Lademann, J., & Patzelt, A. (2014). Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 196-201.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

1. Definition Collagen Extract:

Collagen extract is a protein derived from animal connective tissues, such as bones, skin, and cartilage, that is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties.

2. Use:

Collagen extract is often included in skincare products such as creams, serums, and masks to help improve skin elasticity, reduce the appearance of wrinkles, and promote a more youthful complexion. It is also used in haircare products to strengthen and nourish hair strands.

3. Usage Collagen Extract:

When using skincare products containing collagen extract, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is best to use collagen extract products consistently to see the desired results over time.

Precautions: While collagen extract is generally considered safe for most people, individuals with sensitive skin or allergies to animal-derived ingredients should perform a patch test before using products containing collagen extract. It is also important to consult a dermatologist before incorporating collagen extract into your skincare routine, especially if you have any underlying skin conditions.

4. References:

- Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacology and Physiology, 27(3), 113-119.

1. Definition Palmitoyl Pentapeptide 4:

Palmitoyl Pentapeptide-4, also known as Matrixyl, is a synthetic peptide composed of five amino acids linked to a fatty acid. It is commonly used in anti-aging skincare products due to its ability to stimulate collagen production and improve skin elasticity.

2. Use:

Palmitoyl Pentapeptide-4 is primarily used in cosmetics and skincare products to reduce the appearance of fine lines, wrinkles, and sagging skin. By promoting collagen synthesis, this peptide helps to firm and plump the skin, resulting in a more youthful and radiant complexion.

3. Usage Palmitoyl Pentapeptide 4:

Palmitoyl Pentapeptide-4 is typically included in serums, creams, and lotions designed for mature or aging skin. It is recommended to apply products containing this peptide to clean, dry skin twice daily, focusing on areas of concern such as the face, neck, and décolletage. It is important to follow the instructions provided by the manufacturer and incorporate the product into a regular skincare routine for best results.

4. References:

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.

- Darlenski, R., & Surber, C. (2013). Topical delivery of cosmetic actives: an overview. Skin Pharmacology and Physiology, 26(5), 245-260.

- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., ... & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin. The American journal of pathology, 168(6), 1861-1868.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

1. Definition Fullerenes:

Fullerenes are a type of carbon molecule that take the form of a hollow sphere, ellipsoid, or tube. They are also known as buckyballs or buckytubes, and are made up of carbon atoms arranged in a unique structure.

2. Use:

Fullerenes have gained popularity in the cosmetics industry due to their antioxidant properties. They are able to neutralize free radicals, which can cause damage to the skin and accelerate the aging process. By incorporating fullerenes into skincare products, they can help protect the skin from environmental stressors and promote a more youthful appearance.

3. Usage Fullerenes:

When using cosmetics containing fullerenes, it is important to follow the instructions provided by the manufacturer. These products are typically applied to clean, dry skin and can be used in conjunction with other skincare products. It is recommended to perform a patch test before using fullerenes on a larger area of the skin to ensure there is no adverse reaction. Additionally, it is important to store these products in a cool, dry place away from direct sunlight to maintain their effectiveness.

4. References:

- Shin, H. W., et al. (2016). Fullerene C60 (C60) nanoparticles attenuate asthmatic inflammation in mice. Particle and Fibre Toxicology, 13(1), 1-11.

- Zhang, L., et al. (2019). Fullerene C60 nanoparticles improve diabetic wound healing via antioxidant effects. Nanoscale Research Letters, 14(1), 1-10.

- Chen, Y., et al. (2017). Fullerene-based nanomaterials for cancer therapy. Small, 13(23), 1-18.

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.