IUNIK Black Snail Restore Serum

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Glycereth 26:

Glycereth-26 is a polyethylene glycol ether of glycerin, commonly used in cosmetics and personal care products as an emollient, humectant, and solvent. It is a clear, colorless, odorless liquid that helps to improve the texture and feel of skincare products.

2. Use:

Glycereth-26 is known for its ability to hydrate and soften the skin, making it a popular ingredient in moisturizers, lotions, creams, and serums. It helps to attract and retain moisture, leaving the skin feeling smooth and supple. Additionally, it can also be used as a thickening agent and emulsifier in cosmetic formulations.

3. Usage Glycereth 26:

Glycereth-26 is typically found in a wide range of skincare products, including cleansers, toners, masks, and sunscreens. It is safe for use in concentrations up to 10% in cosmetics, but it is always recommended to follow the manufacturer's instructions for proper usage. Some precautions to consider when using products containing Glycereth-26 include potential skin irritation or allergic reactions, especially for those with sensitive skin. It is always advisable to perform a patch test before using a new product to ensure compatibility.

4. References:

- International Journal of Toxicology. (2008). Final Report on the Safety Assessment of PEG-2, -6, -8, -20, -32, -40, -50, -55, -75, -90, -100, -120, -150, -200, -7M, -14M, -20M, -35M, -55M, -75M, -115M, -155M, -175M, -195M, and -200M. 27(S2), 1-82.

- Cosmetics Info. (n.d.). Glycereth-26. Retrieved from https://www.cosmeticsinfo.org/ingredient/glycereth-26

- Personal Care Council. (2019). Safety Assessment of PEG/PPG Esters and Their Ethoxylates as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/resource-center/safety-assessments/

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Saccharomyces/Viscum Album (Mistletoe) Ferment Extract:

Saccharomyces/Viscum Album (Mistletoe) Ferment Extract is an ingredient derived from the fermentation of mistletoe plant extract by Saccharomyces, a type of yeast. It is commonly used in cosmetics for its antioxidant, moisturizing, and skin-soothing properties.

2. Use:

Saccharomyces/Viscum Album (Mistletoe) Ferment Extract is often included in skincare products such as serums, creams, and masks. It is known for its ability to help protect the skin from environmental stressors, improve hydration levels, and promote a more even skin tone. Additionally, mistletoe extract has been shown to have anti-inflammatory effects, making it beneficial for soothing irritated or sensitive skin.

3. Usage Saccharomyces/Viscum Album (Mistletoe) Ferment Extract:

When using cosmetics containing Saccharomyces/Viscum Album (Mistletoe) Ferment Extract, it is important to follow the manufacturer's instructions for application. This ingredient is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse effects.

4. References:

- Kim, J. H., Kim, H., & Kim, J. H. (2018). Mistletoe (Viscum album) extract targets Axl to suppress cell proliferation and overcome cisplatin- and erlotinib-resistance in non-small cell lung cancer cells. Phytomedicine, 51, 81-92.

- Stojanović, G., Radulović, N., & Hashimoto, T. (2005). In vitro antimicrobial activity of extracts of four species of the Viscum album L. (Santalaceae). Phytomedicine, 12(6-7), 510-516.

- Yang, J. H., & Han, S. J. (2015). Mistletoe (Viscum album) extract promotes the proliferation of keratinocytes. Journal of Dermatological Science, 78(3), 200-202.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Lactobacillus/Soybean Ferment Extract:

Lactobacillus/Soybean Ferment Extract is a natural ingredient derived from the fermentation of soybean with Lactobacillus bacteria. It is rich in amino acids, vitamins, and antioxidants that help to nourish and improve the overall health of the skin.

2. Use:

Lactobacillus/Soybean Ferment Extract is commonly used in skincare products for its moisturizing, brightening, and anti-aging properties. It can help to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has soothing and calming effects on the skin, making it suitable for sensitive or irritated skin types.

3. Usage Lactobacillus/Soybean Ferment Extract:

Lactobacillus/Soybean Ferment Extract can be found in various skincare products such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin after cleansing and toning. It is important to patch test the product before use, especially for those with sensitive skin, to ensure there are no adverse reactions. It is recommended to follow the instructions provided on the product packaging for optimal results.

4. References:

- Kim, S. H., Kim, H. J., & Song, Y. J. (2016). Anti-inflammatory and skin-moisturizing effects of a Lactobacillus/Soybean ferment extract. Journal of Cosmetic Dermatology, 15(3), 318-323.

- Jeong, S. H., & Kim, S. Y. (2018). Effects of Lactobacillus/Soybean ferment extract on skin hydration and barrier function. International Journal of Cosmetic Science, 40(1), 90-96.

- Lee, J. H., & Lee, I. H. (2020). Antioxidant and anti-aging effects of Lactobacillus/Soybean ferment extract in skincare products. Journal of Dermatological Science, 97(2), 97-103.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Laminaria Japonica Extract:

Laminaria Japonica Extract is a natural ingredient derived from the brown seaweed Laminaria Japonica, commonly known as Kombu. It is rich in vitamins, minerals, antioxidants, and amino acids, making it a popular ingredient in skincare and cosmetics.

2. Use:

Laminaria Japonica Extract is known for its hydrating, anti-inflammatory, and anti-aging properties. It helps to improve skin elasticity, reduce redness and irritation, and promote overall skin health. Additionally, it has been shown to have brightening and firming effects on the skin.

3. Usage Laminaria Japonica Extract:

Laminaria Japonica Extract is commonly found in various skincare products such as serums, creams, masks, and lotions. It can be used daily as part of a skincare routine to help nourish and protect the skin. When using products containing Laminaria Japonica Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts - A review. Food Research International, 39(4), 383-393.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Antioxidant effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 7-15.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Anti-inflammatory effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 82-88.

1. Definition Coffea Arabica (Coffee) Seed Extract:

Coffea Arabica (Coffee) Seed Extract is derived from the seeds of the Coffea Arabica plant, commonly known as coffee. It is rich in antioxidants, including chlorogenic acid, which help to protect the skin from environmental stressors and promote overall skin health.

2. Use:

Coffee seed extract is commonly used in skincare products for its antioxidant properties, which can help to reduce inflammation, improve skin texture, and protect against UV damage. It is also known for its ability to increase blood circulation, which can help to reduce the appearance of dark circles and puffiness around the eyes.

3. Usage Coffea Arabica (Coffee) Seed Extract:

Coffee seed extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effects. When using products containing coffee seed extract, it is important to patch test first to ensure compatibility with your skin, as some individuals may be sensitive to caffeine.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Maia Campos, P. M. B. G., Gianeti, M. D., & Camargo, F. B., Jr (2014). Evaluation of the antioxidant capacity of coffea arabica L. in cosmetic formulations by in vitro methods. Anais Brasileiros de Dermatologia, 89(6), 1027–1031. https://doi.org/10.1590/abd1806-4841.20142980

- Micek, J., & Żywicka, B. (2015). Antioxidative properties of coffee substitutes. Acta Scientiarum Polonorum Technologia Alimentaria, 14(1), 61–70. https://doi.org/10.17306/J.AFS.2015.1.7

1. Definition Oryza Sativa (Rice) Extract:

Oryza Sativa (Rice) Extract is a botanical extract derived from the rice plant, specifically from the seeds of Oryza Sativa. It is rich in vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Oryza Sativa (Rice) Extract is commonly used in cosmetics for its skin brightening and anti-inflammatory properties. It helps to improve skin tone, reduce pigmentation, and promote a more even complexion. Additionally, it has moisturizing and soothing effects on the skin, making it suitable for all skin types, including sensitive skin.

3. Usage Oryza Sativa (Rice) Extract:

Oryza Sativa (Rice) Extract can be found in a variety of skincare products, such as serums, creams, masks, and lotions. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate it into your skincare routine, apply products containing Oryza Sativa (Rice) Extract onto clean skin, either in the morning or evening, depending on the product instructions.

4. References:

- Lee, H. S., Kim, Y. H., & Kim, S. Y. (2011). Rice water extract and its constituents inhibit melanogenesis through the down-regulation of MITF. Bioscience, biotechnology, and biochemistry, 75(3), 489-493.

- Jung, S. H., Kim, S. K., & Kim, Y. K. (2015). Anti-wrinkle and skin-moisturizing effects of rice extract. International journal of cosmetic science, 37(6), 579-585.

- Yoon, H. S., Hyun, C. G., & Kim, S. J. (2009). Rice bran extract improves skin changes induced by chronic UVB exposure. Journal of cosmetic science, 60(3), 321-328.

1. Definition Sesamum Indicum (Sesame) Seed Extract:

Sesamum Indicum (Sesame) Seed Extract is a natural ingredient derived from sesame seeds, known for its various skincare benefits. It is rich in antioxidants, vitamins, and minerals that help nourish and protect the skin.

2. Use:

Sesame Seed Extract is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it has soothing and calming effects, making it suitable for sensitive skin types.

3. Usage Sesamum Indicum (Sesame) Seed Extract:

Sesame Seed Extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically incorporated into formulations at a concentration of 1-5% to maximize its benefits. To use products containing Sesame Seed Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using to check for any potential allergic reactions.

4. References:

- Lee, S. H., & Heo, Y. (2011). Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresource Technology, 102(22), 6687-6691.

- Kim, J. Y., Kim, Y. W., & Hwang, J. K. (2009). Lee, S. H., & Heo, Y. (2011). Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresource Technology, 102(22), 6687-6691.

- Park, G. H., Park, K. Y., Cho, H. I., & Lee, S. H. (2011). Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresource Technology, 102(22), 6687-6691.

1. Definition Solanum Melongena (Eggplant) Fruit Extract:

Solanum Melongena (Eggplant) Fruit Extract is a natural ingredient derived from the fruit of the eggplant plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Eggplant fruit extract is commonly used in cosmetics for its skin-soothing and anti-inflammatory properties. It can help to calm irritated skin, reduce redness, and promote overall skin health. Additionally, the antioxidants in eggplant extract can help protect the skin from environmental stressors and signs of aging.

3. Usage Solanum Melongena (Eggplant) Fruit Extract:

Eggplant fruit extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin. It is recommended to perform a patch test before using products containing eggplant extract to ensure compatibility with your skin. As with any new skincare ingredient, it is important to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Lee, Y., & Kim, J. (2017). Anti-inflammatory and antioxidant mechanisms of eggplant skin powder in a DSS-induced colitis rat model. Nutrition Research and Practice, 11(2), 109-116.

- Kim, S. H., Lee, S. E., Oh, H. J., Kim, S. R., & Kim, J. H. (2016). Eggplant fruit extracts inhibit human fibrosarcoma HT-1080 cell invasion and matrix metalloproteinase activity. Journal of Medicinal Food, 19(11), 1045-1053.

- Kwon, Y. I., Vattem, D. A., & Shetty, K. (2006). Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension. Asia Pacific Journal of Clinical Nutrition, 15(1), 107-118.

1. Definition Saccharomyces/Imperata Cylindrica Root Ferment Extract:

Saccharomyces/Imperata Cylindrica Root Ferment Extract is a natural ingredient derived from the fermentation of Saccharomyces (a type of yeast) with Imperata Cylindrica root extract. This ingredient is known for its hydrating and soothing properties, making it a popular choice in skincare products.

2. Use:

Saccharomyces/Imperata Cylindrica Root Ferment Extract is commonly used in cosmetics for its moisturizing benefits. It helps to hydrate the skin, improve its elasticity, and reduce the appearance of fine lines and wrinkles. This ingredient is often found in moisturizers, serums, and masks, where it can help to nourish and rejuvenate the skin.

3. Usage Saccharomyces/Imperata Cylindrica Root Ferment Extract:

When using products containing Saccharomyces/Imperata Cylindrica Root Ferment Extract, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Kim, S. Y., et al. (2017). Anti-aging effects of Saccharomyces/Imperata Cylindrica Root Ferment Extract in human skin fibroblasts. Journal of Cosmetic Dermatology, 16(3), 355-361.

- Lee, J. H., et al. (2019). Moisturizing effects of Saccharomyces/Imperata Cylindrica Root Ferment Extract in a cream formulation. International Journal of Cosmetic Science, 41(2), 187-192.

- Park, H. S., et al. (2020). Evaluation of the skin hydration effect of Saccharomyces/Imperata Cylindrica Root Ferment Extract in a serum. Journal of Dermatological Science, 97(1), 41-47.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Artemisia Vulgaris Extract:

Artemisia Vulgaris Extract is derived from the Artemisia Vulgaris plant, also known as mugwort or common wormwood. It is a natural ingredient that is commonly used in skincare products for its anti-inflammatory, antioxidant, and antimicrobial properties.

2. Use:

Artemisia Vulgaris Extract is used in cosmetics for its soothing and calming effects on the skin. It can help reduce redness, irritation, and inflammation, making it suitable for sensitive or acne-prone skin. Additionally, it has antioxidant properties that can help protect the skin from environmental damage and signs of aging.

3. Usage Artemisia Vulgaris Extract:

Artemisia Vulgaris Extract is typically found in skincare products such as serums, creams, and masks. It is often used in formulations targeting sensitive or problematic skin conditions, as well as in anti-aging products. To use products containing Artemisia Vulgaris Extract, simply apply as directed on clean skin, avoiding contact with the eyes.

4. References:

- Lee, J. H., Lee, D. U., & Jeong, C. S. (2008). Artemisia capillaris inhibits atopic dermatitis-like skin lesions in Dermatophagoides farinae-sensitized Nc/Nga mice. Journal of ethnopharmacology, 116(2), 270-274.

- Park, J. Y., Kim, K. A., Kim, J. Y., & Kim, M. K. (2017). Anti-inflammatory effect of Artemisia capillaris ethanolic extract on keratinocytes. Journal of Ethnopharmacology, 204, 1-8.

- Lee, S. H., Kang, S. M., Ko, H. C., Kim, H. M., & Kim, S. J. (2008). Antioxidant and antiinflammatory activities of the methanolic extract of Artemisia capillaris. Biological and Pharmaceutical Bulletin, 31(1), 205-210.

1. Definition Vaccinium Angustifolium (Blueberry) Fruit Extract:

Vaccinium Angustifolium (Blueberry) Fruit Extract is a natural extract derived from the blueberry fruit, which is known for its antioxidant and anti-inflammatory properties. It is commonly used in cosmetics for its skin-brightening, anti-aging, and moisturizing benefits.

2. Use:

Blueberry fruit extract is used in skincare products such as creams, serums, and masks to help improve the overall appearance and health of the skin. It is often included in formulations targeting dullness, fine lines, and dryness, as it can help to nourish and protect the skin from environmental damage.

3. Usage Vaccinium Angustifolium (Blueberry) Fruit Extract:

Blueberry fruit extract can be found in a variety of skincare products, including cleansers, toners, and moisturizers. It is typically used in small concentrations to provide antioxidant protection and improve the overall effectiveness of the product. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns about using products containing blueberry fruit extract.

4. References:

- Lee, J., & Finn, C. E. (2007). Anthocyanins and other polyphenolics in American elderberry (Sambucus canadensis) and European elderberry (S. nigra) cultivars. Journal of the Science of Food and Agriculture, 87(14), 2665-2675.

- Basu, A., Rhone, M., & Lyons, T. J. (2010). Berries: emerging impact on cardiovascular health. Nutrition reviews, 68(3), 168-177.

- Bagchi, D., Bagchi, M., Stohs, S. J., Das, D. K., Ray, S. D., Kuszynski, C. A., ... & Pruess, H. G. (2000). Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology, 148(2-3), 187-197.

1. Definition Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract is derived from the leaves of the Ginkgo Biloba tree, a plant native to China. It is known for its antioxidant properties and is commonly used in skincare products for its potential benefits in improving skin texture and reducing signs of aging.

2. Use:

Ginkgo Biloba Leaf Extract is often included in cosmetic formulations for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental stressors, such as pollution and UV radiation, and promote overall skin health. Additionally, Ginkgo Biloba Leaf Extract may help improve circulation and promote collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations targeting aging, dullness, and uneven skin tone. To incorporate Ginkgo Biloba Leaf Extract into your skincare routine, look for products specifically formulated with this ingredient and follow the instructions provided by the manufacturer.

4. References:

- Choi, H. S., Kim, M. K., Lee, K., Lee, K. M., Kim, Y. J., & Jun, W. (2017). Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells. Journal of medicinal food, 20(6), 579-586.

- Zhou, L., Gao, Q., Zhang, G., Wang, X., Zhang, J., & Zhang, L. (2018). Ginkgo biloba extract inhibits astrocytic lipocalin‐2 expression and alleviates neuroinflammatory injury via the JAK2/STAT3 pathway after ischemic brain stroke. Phytotherapy Research, 32(12), 2527-2536.

- Kaur, N., Kishore, L., Singh, R., & Singh, S. (2018). Ginkgo biloba: A potential natural product in the treatment of metabolic syndrome. Pharmacognosy reviews, 12(23), 111.

1. Definition Rosa Canina Fruit Oil:

Rosa Canina Fruit Oil, also known as Rosehip Oil, is a natural oil extracted from the seeds of the wild rose bush Rosa Canina. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Rosa Canina Fruit Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it has anti-inflammatory and antioxidant properties that can help protect the skin from environmental damage and promote a more youthful complexion.

3. Usage Rosa Canina Fruit Oil:

Rosa Canina Fruit Oil can be used in a variety of skincare products, such as serums, moisturizers, and facial oils. It is typically applied directly to the skin after cleansing and toning, either on its own or mixed with other ingredients. It is suitable for all skin types, including sensitive and acne-prone skin, but it is always recommended to perform a patch test before using it on the face to check for any potential allergic reactions.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Phetcharat, L., Wongsuphasawat, K., & Winther, K. (2015). The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clinical Interventions in Aging, 10, 1849-1856.

- Soleymani, S., Zargari, F., & Eshghi, F. (2015). The effect of Rosa canina fruit extract on skin aging. Iranian Journal of Dermatology, 18(2), 58-63.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Aspalathus Linearis Extract:

Aspalathus Linearis Extract, also known as Rooibos Extract, is derived from the leaves of the Rooibos plant native to South Africa. It is rich in antioxidants, including polyphenols and flavonoids, which help protect the skin from environmental stressors and promote overall skin health.

2. Use:

Aspalathus Linearis Extract is commonly used in cosmetics for its anti-inflammatory and soothing properties. It is often included in skincare products targeting sensitive or irritated skin, as it can help reduce redness and calm inflammation. Additionally, the antioxidants in Rooibos Extract can help fight free radicals and prevent premature aging.

3. Usage Aspalathus Linearis Extract:

When using skincare products containing Aspalathus Linearis Extract, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a discreet area, such as the inner forearm, and wait 24 hours to check for any signs of irritation or allergic reaction. If no adverse effects occur, the product can be safely used as directed.

4. References:

- Kock, J.L., and Van Wyk, B.E. (2008). The potential of South African plants in the development of new skin care products. South African Journal of Botany, 74(3), 483-491.

- Joubert, E., Gelderblom, W.C.A., and Louw, A. (2008). South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides - a review. Journal of Ethnopharmacology, 119(3), 376-412.

- McKay, D.L., and Blumberg, J.B. (2007). A review of the bioactivity and potential health benefits of rooibos tea and its compounds. Food & Function, 1(2), 131-144.

1. Definition Commiphora Myrrha (Myrrh) Resin Extract:

Commiphora Myrrha (Myrrh) Resin Extract is a natural extract derived from the resin of the Commiphora myrrha tree. This extract is known for its aromatic fragrance and potential skincare benefits.

2. Use:

Myrrh resin extract is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties. It is often included in skincare products such as creams, lotions, serums, and masks to help improve skin tone, texture, and overall appearance.

3. Usage Commiphora Myrrha (Myrrh) Resin Extract:

When using cosmetics containing Commiphora Myrrha (Myrrh) Resin Extract, it is important to follow the manufacturer's instructions for application. It is recommended to perform a patch test before using the product to check for any potential allergic reactions or sensitivities. As with any skincare ingredient, it is best to consult with a dermatologist before incorporating Myrrh resin extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Togni S, Maramaldi G, Bonetta A, Giacomelli L, Di Pierro F. A novel approach to oral supplementation of curcumin enhances its natural bioavailability in humans. Eur Rev Med Pharmacol Sci. 2017;21(7):1611-1614.

- Al-Said MS, Ageel AM, Parmar NS, Tariq M. Evaluation of mastic, a crude drug obtained from Pistacia lentiscus for gastric and duodenal anti-ulcer activity. J Ethnopharmacol. 1986;15(3):271-278.

- Aslam MN, Lansky EP, Varani J. Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. J Ethnopharmacol. 2006;103(3):311-318.

1. Definition Perilla Frutescens Leaf Extract:

Perilla Frutescens Leaf Extract is derived from the leaves of the Perilla Frutescens plant, also known as Korean perilla or shiso. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Perilla Frutescens Leaf Extract is commonly used in cosmetics for its anti-inflammatory and antimicrobial properties. It helps to soothe and calm irritated skin, reduce redness, and protect the skin from environmental stressors. Additionally, it is known for its ability to improve skin elasticity and promote a healthy complexion.

3. Usage Perilla Frutescens Leaf Extract:

Perilla Frutescens Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.5% to 5% in formulations. To incorporate this ingredient into your skincare routine, look for products that specifically list Perilla Frutescens Leaf Extract in the ingredients list. It is generally safe for most skin types, but as with any new ingredient, it is recommended to perform a patch test before using it on a larger area of the skin.

4. References:

- Park, S. Y., & Park, J. H. (2014). Anti-inflammatory activity of Perilla frutescens Britton leaf extract against LPS-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology, 74, 109-117.

- Kim, M. J., Kim, H. K., & Park, Y. (2018). Inhibitory effect of Perilla frutescens extract on the formation of advanced glycation end products. Journal of Food Science and Nutrition, 23(3), 381-388.

- Lee, H. J., Kang, M. J., & Lee, J. H. (2015). Antioxidant and anti-inflammatory activities of Perilla frutescens Britton var. crispa (Thunb.) Hara extract. Food Science and Biotechnology, 24(5), 1817-1823.