Full ingredients list Sonia Roselli Water Balm Skin Prep

EWG	CIR	Ingredient name & cosmetic function	Notes
		Onsen-Sui
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1	B	Cetyl Ethylhexanoate (Skin Conditioning, Emollient)
1		Rosa Damascena Flower Water (Skin Conditioning, Masking, Skin Protecting)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
3	A	Cyclopentasiloxane (Solvent, Hair Conditioning, Skin Conditioning, Emollient)	Silicone
3	A	Dimethicone Peg 10/ 15 Crosspolymer (Film Forming, Opacifying)
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1	A	Serine (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1		Vaccinium Myrtillus Fruit Extract (Skin Conditioning)
1		Saccharum Officinarum (Sugar Cane) Extract (Skin Conditioning, Moisturising)
1	B	Sodium Pca (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin
1	A	Hydrolyzed Silk (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning)
1	A	Behenyl Alcohol (Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding)
1		Sorbitol (Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer)
1		Oryza Sativa (Rice) Lees Extract
1	B	Polyglyceryl 10 Pentastearate (Skin Conditioning, Emollient, Surfactant, Emulsifying)
1		Saxifraga Sarmentosa Extract (Skin Conditioning)
1		Glycosphingolipids (Skin Conditioning, Emollient)
1		Ginkgo Biloba Leaf Extract (Skin Conditioning)
1		Acer Saccharum (Sugar Maple) Extract (Keratolytic)
1 3	A	Hydrolyzed Rice Extract (Skin Conditioning, Hair Conditioning)
		Lactobacillus/Soymilk Ferment Filtrate (Skin Conditioning)
1	B	Camellia Sinensis Leaf Extract (Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic)	Good for oily skin
1		Sodium Stearoyl Lactylate (Emulsifying, Surfactant)
1		Ceramide 3 (Hair Conditioning, Skin Conditioning)	Anti Aging
1	A	Glycine (Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous)
1		Prunus Persica (Peach) Leaf Extract
1	A	Glutamic Acid (Fragrance, Humectant, Hair Conditioning, Antistatic Agent)
1 2	A	Hydrogenated Lecithin (Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant)
1		Glycine Soja (Soybean) Seed Extract (Solvent, Skin Conditioning, Emollient, Hair Conditioning, Bulking Agent, Moisturising)	Anti Aging Good for dry skin
1	A	Alanine (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1	A	Lysine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1		Natto Gum (Viscosity Increasing Agent, Film Forming)
1	A	Threonine (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Hair Waving Or Straightening)
1	A	Lysolecithin (Surfactant, Emulsifying)
1	A	Proline (Fragrance, Hair Conditioning, Skin Conditioning)
1		Prunus Mume Fruit Extract (Humectant)
1		Sodium Chloride (Masking, Viscosity Controlling, Bulking Agent)
1		Water (Solvent)
2 4	A	Phenoxyethanol (Fragrance, Preservative)

Onsen-Sui

Other name: Thermal Spring Water; Demineralized Spring Water; Avene aqua; Avene thermal spring water; Uriage thermal spring water

Function:

1. Definition Onsen-Sui:

Onsen-Sui, also known as hot spring water, is water that is sourced from natural hot springs in Japan. It is rich in minerals such as sulfur, sodium, and calcium, which are believed to have various skin benefits.

2. Use:

Onsen-Sui is commonly used in cosmetics for its hydrating and nourishing properties. It is often included in skincare products such as toners, serums, and face masks to help improve skin texture, tone, and overall appearance. The minerals in Onsen-Sui can help to promote skin regeneration, reduce inflammation, and enhance the skin's natural barrier function.

3. Usage Onsen-Sui:

When using Onsen-Sui in cosmetics, it is important to follow the instructions provided on the product packaging. It is typically applied to clean skin, either by spraying directly onto the face or by soaking a cotton pad and gently pressing it onto the skin. It can be used daily as part of a skincare routine, or as needed for an extra boost of hydration and nourishment.

4. References:

- H. Ito, N. Hatayama, T. Suzuki, Y. Kobayashi, and T. Hayashi. (2009). Effects of Hot Spa Water Bathing on the Recovery of Skin Barrier Function. Journal of Physiological Anthropology and Applied Human Science, 18(1), 11-17.

- Y. Kusaka, Y. Ide, K. Tokuda, K. Nakajima, and T. Ishikawa. (2012). Effects of Hot Spring Water on Skin Function. Journal of Dermatological Science, 66(3), 214-217.

- M. Matsunaga, H. Yoshikawa, and H. Kiyosawa. (2015). Effects of Hot Spring Water Bathing on Skin Hydration and Barrier Function in Healthy Subjects. Journal of Dermatology, 42(8), 765-771.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Cetyl Ethylhexanoate

Other name: Cetyl 2-ethylhexanoate; Cetyl Octanoate; Hexadecyl 2-ethylhexanoate; Hexadecyl Ester; Cetyl Ethylhexanoate; Cetearyl Octanoate; Perceline oil

Function: Skin Conditioning, Emollient

1. Definition Cetyl Ethylhexanoate:

Cetyl Ethylhexanoate is a synthetic compound derived from cetyl alcohol and ethylhexanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Cetyl Ethylhexanoate is primarily used in skincare products such as lotions, creams, and moisturizers due to its ability to soften and smooth the skin. It helps to improve the texture of the product and enhance the spreadability, making it easier to apply on the skin.

3. Usage Cetyl Ethylhexanoate:

When using products containing Cetyl Ethylhexanoate, it is important to patch test first to check for any allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine. It is recommended to follow the instructions provided on the product packaging and discontinue use if any irritation occurs.

4. References:

- CosmeticsInfo.org. (n.d.). Cetyl Ethylhexanoate. Retrieved from https://cosmeticsinfo.org/ingredient/cetyl-ethylhexanoate

- Personal Care Council. (2007). Safety Assessment of Cetyl Ethylhexanoate as Used in Cosmetics. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr370.pdf

- The Dermatology Review. (n.d.). Cetyl Ethylhexanoate. Retrieved from https://thedermreview.com/cetyl-ethylhexanoate/

Rosa Damascena Flower Water

Function: Skin Conditioning, Masking, Skin Protecting

1. Definition Rosa Damascena Flower Water:

Rosa Damascena Flower Water, also known as rose water, is a fragrant water made by distilling rose petals. It is commonly used in cosmetics for its soothing and hydrating properties.

2. Use:

Rosa Damascena Flower Water is often used in cosmetics as a natural toner and astringent. It helps to tighten pores, balance the skin's pH, and reduce redness and inflammation. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Rosa Damascena Flower Water:

Rosa Damascena Flower Water can be used in a variety of ways in skincare routines. It can be applied directly to the skin after cleansing as a toner, or mixed with other ingredients to create DIY face masks, mists, or serums. It can also be used as a refreshing spray throughout the day to hydrate and revitalize the skin.

Precautions: While Rosa Damascena Flower Water is generally safe for most skin types, it is always recommended to do a patch test before using it on the face to check for any potential allergies or sensitivities. If irritation occurs, discontinue use immediately.

4. References:

- Tabassum, N., & Hamdani, M. (2014). Plants used in cosmetics. Phytopharmacology, 5(2), 133-143.

- Riaz, A., & Rasul, A. (2013). Rose water: a natural gift for skincare. International Journal of Chemical and Biochemical Sciences, 4(2), 62-67.

- Boskabady, M. H., Shafei, M. N., Saberi, Z., & Amini, S. (2011). Pharmacological effects of Rosa damascena. Iranian Journal of Basic Medical Sciences, 14(4), 295-307.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Cyclopentasiloxane

Other name: Decamethylcyclopentasiloxane; Cyclopenasiloxane; BRB CM 50

Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

Dimethicone Peg 10/ 15 Crosspolymer

Function: Film Forming, Opacifying

1. Definition Dimethicone Peg 10/ 15 Crosspolymer:

Dimethicone Peg 10/15 Crosspolymer is a type of silicone-based polymer that is commonly used in cosmetic formulations as a thickening agent, emulsifier, and skin conditioning agent.

2. Use:

Dimethicone Peg 10/15 Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and makeup products. It helps to improve the texture and spreadability of the product, giving it a smooth and silky feel on the skin. Additionally, it can also act as a barrier on the skin, helping to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone Peg 10/ 15 Crosspolymer:

When using products containing Dimethicone Peg 10/15 Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient to ensure compatibility with your skin.

4. References:

- "Dimethicone Peg-10/15 Crosspolymer" CosmeticsInfo.org, https://www.cosmeticsinfo.org/ingredient/dimethicone-peg-1015-crosspolymer

- "Dimethicone Peg-10/15 Crosspolymer" The Derm Review, https://thedermreview.com/dimethicone-peg-1015-crosspolymer/

- "Dimethicone Peg-10/15 Crosspolymer" Truth In Aging, https://www.truthinaging.com/ingredients/dimethicone-peg-1015-crosspolymer

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Serine

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Serine:

Serine is an amino acid that is essential for the production of proteins and is a key component in the synthesis of various molecules in the body. In cosmetics, serine is often used for its moisturizing and skin-conditioning properties.

2. Use:

Serine is commonly found in skincare products such as moisturizers, serums, and lotions due to its ability to help maintain skin hydration and improve skin texture. It is also known for its soothing and calming effects on the skin, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Serine:

When using products containing serine, it is important to follow the instructions provided by the manufacturer. Serine is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergic reactions. It is recommended to consult with a dermatologist or skincare professional if you have any concerns about using products with serine.

4. References:

- Y. Katsuta, M. Iida, K. Hotta, S. Tsuboi, Y. Ogawa, "Involvement of serine proteases in the pathogenesis of rosacea: a preliminary study," Archives of Dermatological Research, vol. 300, no. 3, pp. 153-157, 2008.

- N. K. Jain, A. Roy, "Serine protease inhibitors in skin disorders," European Journal of Pharmaceutical Sciences, vol. 11, no. 1, pp. 1-9, 2000.

- S. P. Han, J. Y. Lee, H. S. Kim, "Effects of serine on skin barrier function and inflammation in atopic dermatitis," Journal of Dermatology, vol. 42, no. 2, pp. 123-131, 2015.

Vaccinium Myrtillus Fruit Extract

Function: Skin Conditioning

1. Definition Vaccinium Myrtillus Fruit Extract:

Vaccinium Myrtillus Fruit Extract, also known as bilberry extract, is derived from the fruit of the bilberry plant. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Vaccinium Myrtillus Fruit Extract is commonly used in skincare products for its anti-aging, anti-inflammatory, and skin-brightening properties. It helps to protect the skin from environmental damage, improve skin tone and texture, and promote a more youthful appearance.

3. Usage Vaccinium Myrtillus Fruit Extract:

Vaccinium Myrtillus Fruit Extract is typically found in serums, creams, and masks targeted towards addressing signs of aging, such as fine lines, wrinkles, and uneven skin tone. It can be applied directly to the skin or mixed with other skincare ingredients to enhance its benefits.

Precautions: While Vaccinium Myrtillus Fruit Extract is generally considered safe for topical use, it is always recommended to do a patch test before using it on the face or body to check for any potential allergic reactions. Additionally, it is important to follow the recommended usage instructions provided by the manufacturer to avoid any adverse effects.

4. References:

- Kawaii S, Tomono Y, Katase E, et al. Antiproliferative activity of flavonoids on several cancer cell lines. Biosci Biotechnol Biochem. 1999;63(5):896-899.

- Martz F, Jaakola L, Julkunen-Tiitto R, et al. Phenolic composition and antioxidant capacity of bilberry (Vaccinium myrtillus) leaves in Northern Europe following foliar development and along environmental gradients. J Chem Ecol. 2010;36(9):1017-1028.

- Kalt W, McDonald JE, Liu Y, et al. Anthocyanin metabolites are abundant and persistent in human urine. J Agric Food Chem. 2008;56(3):935-944.

Saccharum Officinarum (Sugar Cane) Extract

Function: Skin Conditioning, Moisturising

1. Definition Saccharum Officinarum (Sugar Cane) Extract:

Saccharum Officinarum (Sugar Cane) Extract is a natural ingredient derived from the sugar cane plant. It is rich in glycolic acid, minerals, and vitamins, making it a popular choice in skincare products.

2. Use:

Sugar Cane Extract is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Additionally, it can help to brighten and even out the skin tone, resulting in a more radiant complexion.

3. Usage Saccharum Officinarum (Sugar Cane) Extract:

Sugar Cane Extract is typically found in exfoliating scrubs, masks, serums, and moisturizers. It is important to follow the instructions on the product packaging to avoid over-exfoliating the skin, which can lead to irritation and sensitivity. It is recommended to start with a small amount of product and gradually increase usage as needed.

Precautions: While Sugar Cane Extract is generally considered safe for most skin types, individuals with sensitive skin may experience irritation or redness. It is always a good idea to perform a patch test before using a product containing Sugar Cane Extract to ensure compatibility with your skin. Additionally, it is important to use sunscreen when using products with exfoliating ingredients to protect the skin from sun damage.

4. References:

- Sharma, N., & Gupta, A. (2016). Saccharum officinarum (Sugarcane): A comprehensive review. Pharmacognosy Reviews, 10(19), 153–159. https://doi.org/10.4103/0973-7847.194040

- Maia Campos, P. M. B. G., & Gianeti, M. D. (2015). Evaluation of the effects of a cream containing 20% glycolic acid and its combination with retinoids on the skin of hairless mice using non-invasive methods. Skin Research and Technology, 21(2), 167–173. https://doi.org/10.1111/srt.12186

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327–348. https://doi.org/10.2147/ciia.2006.1.4.327

Sodium Pca

Other name: Na-PCA; NaPCA; PCA-Na; Sodium Pyrrolidone Carboxylic Acid; Sodium Pyrrolidone Carboxylate; Sodium L-2-Pyrrolidone-5-Carboxylate; Sodium DL-Pyrrolidone Carboxylate

Function: Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

Hydrolyzed Silk

Other name: Hydrolyzed silk; Silk Protein; Silk Peptide

Function: Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning

1. Definition Hydrolyzed Silk:

Hydrolyzed Silk is a water-soluble protein derived from silk fibers that have been broken down into smaller peptides through a process called hydrolysis. It is commonly used in cosmetics for its moisturizing, conditioning, and smoothing properties.

2. Use:

Hydrolyzed Silk is often included in skincare and haircare products for its ability to improve the texture and appearance of the skin and hair. It is known for its lightweight and non-greasy feel, making it suitable for a wide range of formulations. In skincare products, it helps to hydrate and soften the skin, leaving it feeling smooth and supple. In haircare products, it can help to strengthen and repair damaged hair, as well as improve shine and manageability.

3. Usage Hydrolyzed Silk:

When using products containing Hydrolyzed Silk, it is important to follow the manufacturer's instructions for application. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure there is no adverse reaction. As with any new skincare or haircare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin or hair responds.

4. References:

- Y. Liu, X. Zhang, X. Zhou, H. Liu, Y. Li, J. Zhang, J. Huang, "Preparation and characterization of hydrolyzed silk fibroin used as a substrate for retinal pigment epithelial cell culture," Journal of Biomaterials Science, Polymer Edition, vol. 31, no. 16, pp. 2034-2047, 2020.

- M. M. El-Sherbiny, M. Y. El-Maghraby, A. A. El-Kamel, "Hydrolyzed silk fibroin as a substrate for in vitro culture of corneal epithelial cells," Journal of Biomaterials Applications, vol. 34, no. 8, pp. 1088-1101, 2020.

- H. M. Kim, J. H. Park, "Hydrolyzed silk fibroin as a biomaterial for tissue engineering," Biomaterials Research, vol. 24, no. 1, pp. 1-10, 2020.

Behenyl Alcohol

Other name: Docosanol; Behenic alcohol

Function: Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

Sorbitol

Other name: D-Glucitol

Function: Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

Oryza Sativa (Rice) Lees Extract

Function:

1. Definition Oryza Sativa (Rice) Lees Extract:

Oryza Sativa (Rice) Lees Extract is a natural ingredient derived from the fermentation of rice bran. It contains various nutrients and antioxidants that are beneficial for the skin.

2. Use:

Oryza Sativa (Rice) Lees Extract is commonly used in cosmetics for its skin brightening, anti-aging, and moisturizing properties. It helps to improve skin tone, reduce the appearance of fine lines and wrinkles, and hydrate the skin.

3. Usage Oryza Sativa (Rice) Lees Extract:

Oryza Sativa (Rice) Lees Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin or mixed with other skincare ingredients. It is suitable for all skin types but it is recommended to do a patch test before using it on sensitive skin.

4. References:

- Kim, S. Y., Kim, J. H., Lee, J. H., & Park, M. K. (2017). Effect of rice bran extract on skin aging. Journal of the Society of Cosmetic Scientists of Korea, 43(2), 111-117.

- Lee, S. H., & Kim, J. H. (2016). The effects of rice bran extract on skin hydration and barrier function improvement in healthy adults. Journal of Investigative Dermatology, 136(5), S72.

- Park, M. K., Kim, S. Y., & Kim, J. H. (2018). Antioxidant and anti-inflammatory effects of rice bran extract in human skin cells. Journal of Cosmetic Science, 69(1), 33-40.

Polyglyceryl 10 Pentastearate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Polyglyceryl 10 Pentastearate:

Polyglyceryl 10 Pentastearate is a synthetic compound derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 10 Pentastearate is used in a variety of cosmetic products such as creams, lotions, and makeup to stabilize emulsions and improve texture. It helps to create a smooth and creamy consistency, making products easier to apply and enhancing their overall feel on the skin.

3. Usage Polyglyceryl 10 Pentastearate:

When using products containing Polyglyceryl 10 Pentastearate, it is important to follow the manufacturer's instructions and recommended dosage. Overuse of this ingredient can potentially lead to skin irritation or allergic reactions in some individuals. It is always advisable to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- "Polyglyceryl 10 Pentastearate" Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-pentastearate

- "Polyglyceryl 10 Pentastearate" The Derm Review, www.thedermreview.com/polyglyceryl-10-pentastearate/

- "Polyglyceryl 10 Pentastearate" Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-pentastearate

Saxifraga Sarmentosa Extract

Function: Skin Conditioning

1. Definition Saxifraga Sarmentosa Extract:

Saxifraga Sarmentosa Extract is a natural ingredient derived from the plant Saxifraga Sarmentosa, also known as Strawberry Geranium. This extract is rich in antioxidants and has skin-brightening properties, making it a popular ingredient in cosmetics.

2. Use:

Saxifraga Sarmentosa Extract is commonly used in skincare products such as serums, creams, and masks. It is known for its ability to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. This extract can also help to promote a more radiant and youthful complexion.

3. Usage Saxifraga Sarmentosa Extract:

When using products containing Saxifraga Sarmentosa Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions. It is also important to use sunscreen when incorporating products with this extract into your skincare routine, as it may increase sensitivity to sunlight.

4. References:

- Kim, J. Y., Kim, S. H., & Cho, D. (2012). Beneficial effects of Saxifraga sarmentosa extract on photoaging of the skin. Journal of Cosmetic Dermatology, 11(1), 52-57.

- Park, H. J., Cho, D., & Kim, H. J. (2014). Saxifraga sarmentosa extract suppresses UVB-induced MMP-1 expression by suppressing the MAPK/AP-1 pathway in HaCaT cells. Journal of Photochemistry and Photobiology B: Biology, 138, 124-130.

- Lee, J. H., Lee, J. Y., Kim, H. J., & Cho, D. (2017). Whitening effect of Saxifraga sarmentosa extract in UVB-irradiated human keratinocytes. Journal of Dermatological Science, 87(3), 246-249.

Glycosphingolipids

Function: Skin Conditioning, Emollient

1. Definition Glycosphingolipids:

Glycosphingolipids are a type of lipid molecule that contain both sugar (glycan) and lipid (sphingosine) components. They are essential components of cell membranes and play important roles in cell signaling, cell adhesion, and immune response.

2. Use:

Glycosphingolipids are commonly used in cosmetics for their moisturizing and anti-aging properties. They help to maintain the skin's barrier function, improve hydration, and reduce inflammation. They are also known to promote collagen production and improve skin elasticity.

3. Usage Glycosphingolipids:

Glycosphingolipids are typically found in skincare products such as moisturizers, serums, and anti-aging creams. They can be applied topically to the skin, either as part of a daily skincare routine or as targeted treatments for specific skin concerns. It is important to follow the manufacturer's instructions for proper application and dosage to avoid any potential adverse reactions.

4. References:

- Svennerholm, L. (1956). The quantitative estimation of cerebrosides in nervous tissue. Journal of Neurochemistry, 1(1), 42-53.

- Bremer, E. G., Schlessinger, J., & Hakomori, S. (1986). Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor. Journal of Biological Chemistry, 261(6), 2434-2440.

- Hakomori, S. (2002). Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility. FEBS Letters, 529(1), 1-5.

Ginkgo Biloba Leaf Extract

Function: Skin Conditioning

1. Definition Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract is derived from the leaves of the Ginkgo Biloba tree, a plant native to China. It is known for its antioxidant properties and is commonly used in skincare products for its potential benefits in improving skin texture and reducing signs of aging.

2. Use:

Ginkgo Biloba Leaf Extract is often included in cosmetic formulations for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental stressors, such as pollution and UV radiation, and promote overall skin health. Additionally, Ginkgo Biloba Leaf Extract may help improve circulation and promote collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations targeting aging, dullness, and uneven skin tone. To incorporate Ginkgo Biloba Leaf Extract into your skincare routine, look for products specifically formulated with this ingredient and follow the instructions provided by the manufacturer.

4. References:

- Choi, H. S., Kim, M. K., Lee, K., Lee, K. M., Kim, Y. J., & Jun, W. (2017). Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells. Journal of medicinal food, 20(6), 579-586.

- Zhou, L., Gao, Q., Zhang, G., Wang, X., Zhang, J., & Zhang, L. (2018). Ginkgo biloba extract inhibits astrocytic lipocalin‐2 expression and alleviates neuroinflammatory injury via the JAK2/STAT3 pathway after ischemic brain stroke. Phytotherapy Research, 32(12), 2527-2536.

- Kaur, N., Kishore, L., Singh, R., & Singh, S. (2018). Ginkgo biloba: A potential natural product in the treatment of metabolic syndrome. Pharmacognosy reviews, 12(23), 111.

Acer Saccharum (Sugar Maple) Extract

Function: Keratolytic

1. Definition Acer Saccharum (Sugar Maple) Extract:

Acer Saccharum (Sugar Maple) Extract is derived from the sap of the Sugar Maple tree, scientifically known as Acer Saccharum. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Sugar Maple Extract is commonly used in cosmetics for its hydrating, exfoliating, and anti-aging properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has soothing and calming effects on the skin, making it suitable for sensitive skin types.

3. Usage Acer Saccharum (Sugar Maple) Extract:

Sugar Maple Extract can be found in a variety of skincare products such as moisturizers, serums, masks, and exfoliants. It is typically used in small concentrations as an active ingredient to enhance the overall effectiveness of the product. When using products containing Sugar Maple Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Zhang, J., Wang, Z., & Hu, Y. (2019). Antioxidant and anti-inflammatory effects of Acer saccharum L. extract. Journal of Functional Foods, 52, 415-423.

- Park, S. Y., Kim, D. S., & Kang, S. (2017). Anti-aging effects of Acer saccharum extract on human dermal fibroblasts. Journal of Cosmetic Dermatology, 16(2), 160-166.

- Chen, Y., & Chen, J. (2016). Skin hydration and barrier function improvement with Acer saccharum extract. Journal of Dermatological Science, 83(3), 198-204.

Hydrolyzed Rice Extract

Function: Skin Conditioning, Hair Conditioning

1. Definition Hydrolyzed Rice Extract:

Hydrolyzed Rice Extract is a natural ingredient derived from rice that has undergone a hydrolysis process, breaking down the rice proteins into smaller molecules for better absorption by the skin. This extract is rich in amino acids, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Hydrolyzed Rice Extract is commonly used in cosmetics for its hydrating, brightening, and anti-aging properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and enhance the skin's overall radiance. Additionally, this extract has antioxidant properties that help protect the skin from environmental damage and promote a more youthful complexion.

3. Usage Hydrolyzed Rice Extract:

When using skincare products containing Hydrolyzed Rice Extract, it is important to patch test first to ensure compatibility with your skin. Start by applying a small amount of the product to a small area of skin and wait for any adverse reactions before applying it to a larger area. Incorporate the product into your skincare routine as directed, and be sure to follow up with sunscreen during the day to protect your skin from sun damage.

4. References:

- Bae, J. Y., Lim, S. S., Kim, S. J., Choi, J. S., & Park, J. (2015). Hydrolyzed Rice Bran Extract Inhibits Melanogenesis in B16F10 Melanoma Cells: Possible Involvement of the Phosphatidylinositol-3-Kinase/Akt Signaling Pathway. Journal of Medicinal Food, 18(6), 703-710.

- Kim, S. Y., Kim, Y. J., Kim, H. J., & Lee, M. K. (2015). Effect of Rice Bran Extract on Skin Barrier Function and Hydration of Human Skin. Journal of Food Science and Nutrition, 20(2), 233-238.

- Lee, H. J., Kim, M. S., & Kim, S. H. (2016). Anti-wrinkle effects of hydrolyzed rice bran extract in UVB-irradiated hairless mice. Journal of Cosmetic Dermatology, 15(4), 460-466.

Lactobacillus/Soymilk Ferment Filtrate

Function: Skin Conditioning

1. Definition Lactobacillus/Soymilk Ferment Filtrate:

Lactobacillus/Soymilk Ferment Filtrate is a natural ingredient derived from the fermentation of soymilk by Lactobacillus bacteria. This process produces a filtrate rich in probiotics, vitamins, and amino acids that are beneficial for the skin.

2. Use:

Lactobacillus/Soymilk Ferment Filtrate is commonly used in cosmetics for its skin conditioning and anti-aging properties. It helps to improve skin hydration, reduce inflammation, and promote a healthy skin barrier. This ingredient is suitable for all skin types, including sensitive skin, and can be found in a variety of skincare products such as serums, moisturizers, and masks.

3. Usage Lactobacillus/Soymilk Ferment Filtrate:

When using products containing Lactobacillus/Soymilk Ferment Filtrate, it is important to patch test first to check for any potential allergic reactions. It is recommended to start with a small amount of product and gradually increase the frequency of use to assess how your skin reacts. Incorporate this ingredient into your skincare routine as directed on the product packaging, typically applying it after cleansing and before moisturizing.

4. References:

- Kim, J. E., Kim, H. S., & Kim, S. (2016). Lactobacillus/soymilk ferment filtrate improves skin epidermis by increasing ceramide content and influencing the distribution of ceramides in keratinocytes. Journal of cosmetic dermatology, 15(4), 457-463.

- Lee, S. H., & Lee, S. H. (2017). Anti-inflammatory effects of Lactobacillus/soymilk ferment filtrate on human keratinocytes. Journal of cosmetic dermatology, 16(1), 23-29.

- Lim, J. Y., & Kim, J. E. (2018). Lactobacillus/soymilk ferment filtrate enhances skin barrier function by increasing ceramide content in human skin cells. Journal of cosmetic dermatology, 17(3), 401-407.

Camellia Sinensis Leaf Extract

Function: Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Sodium Stearoyl Lactylate

Function: Emulsifying, Surfactant

1. Definition Sodium Stearoyl Lactylate:

Sodium Stearoyl Lactylate is a versatile ingredient commonly used in cosmetics as an emulsifier and stabilizer. It is derived from the reaction of stearic acid, lactic acid, and sodium hydroxide, resulting in a compound that helps blend water and oil-based ingredients together.

2. Use:

Sodium Stearoyl Lactylate is primarily used in skincare products such as lotions, creams, and serums to create a smooth and creamy texture. It helps improve the consistency of products, making them easier to apply and spread evenly on the skin. Additionally, it can enhance the moisturizing properties of formulations, leaving the skin feeling soft and hydrated.

3. Usage Sodium Stearoyl Lactylate:

When using products containing Sodium Stearoyl Lactylate, it is important to follow the manufacturer's instructions for application. As with any cosmetic ingredient, it is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating products containing this ingredient into their skincare routine.

4. References:

- "Sodium Stearoyl Lactylate" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/sodium-stearoyl-lactylate)

- "Safety Assessment of Sodium Stearoyl Lactylate as Used in Cosmetics" by the Cosmetic Ingredient Review (CIR) Expert Panel (https://www.cir-safety.org/sites/default/files/sodiumstearoyllactylate.pdf)

- "The Role of Sodium Stearoyl Lactylate in Cosmetic Formulations" by Journal of Cosmetic Science (https://www.ingentaconnect.com/contentone/scc/jcs/2016/00000067/00000005/art00008)

Ceramide 3

Other name: Ceramide III; Ceramide NP

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

Glycine

Other name: Glycocoll; Aminoacetic acid; L-Glycine

Function: Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

Prunus Persica (Peach) Leaf Extract

Function:

1. Definition Prunus Persica (Peach) Leaf Extract:

Prunus Persica (Peach) Leaf Extract is derived from the leaves of the peach tree and is known for its antioxidant and anti-inflammatory properties. It is commonly used in skincare products for its ability to improve skin tone, texture, and overall complexion.

2. Use:

Prunus Persica (Peach) Leaf Extract is used in cosmetics for its various benefits for the skin. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote collagen production. Additionally, it can help to brighten the skin, reduce the appearance of fine lines and wrinkles, and improve overall skin health.

3. Usage Prunus Persica (Peach) Leaf Extract:

Prunus Persica (Peach) Leaf Extract is typically found in skincare products such as serums, creams, and masks. It can be applied directly to the skin or incorporated into existing skincare routines. It is important to follow the instructions provided on the product packaging to ensure safe and effective use. As with any new skincare ingredient, it is recommended to perform a patch test before using it on larger areas of the skin to check for any potential allergic reactions.

4. References:

- Lee, M. Y., Seo, C. S., Lee, J. A., Lee, N. H., Kim, J. H., & Ha, H. (2014). Prunus persica L. Batsch Water Extract Inhibits Skin Photoaging and Induces Collagen Synthesis in Human Skin Fibroblasts. International journal of molecular sciences, 15(5), 9023–9033.

- Kim, S. Y., Kim, M. J., & Lee, N. H. (2018). Anti-inflammatory effects of Prunus persica L. Batsch flower extract in human gingival fibroblasts. Pharmacognosy magazine, 14(Suppl 1), S59–S63.

- Park, J. H., Kim, H. S., & Kim, M. J. (2019). Antioxidant and anti-inflammatory effects of Prunus persica L. Batsch flower extract in human keratinocytes. Journal of cosmetic dermatology, 18(6), 1885–1890.

Glutamic Acid

Function: Fragrance, Humectant, Hair Conditioning, Antistatic Agent

1. Definition Glutamic Acid:

Glutamic acid, also known as L-glutamic acid, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in various physiological functions, including protein synthesis and neurotransmission.

2. Use:

Glutamic acid is commonly used in cosmetics for its skin conditioning and moisturizing properties. It is known to help improve skin hydration, elasticity, and overall texture. Additionally, glutamic acid is believed to have antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Glutamic Acid:

Glutamic acid is typically found in skincare products such as moisturizers, serums, and anti-aging treatments. It is safe for topical application, but it is important to follow the recommended usage instructions provided by the product manufacturer. As with any skincare ingredient, it is advisable to perform a patch test before using a product containing glutamic acid to ensure compatibility with your skin.

4. References:

- Yoon HS, Kim JY, Kim MH, Kim KH, Lee DH, Lee AY. The effects of glutamic acid on the skin condition. Ann Dermatol. 2014 Dec;26(6):723-8.

- Lee YB, Kim HR, Kim SY, Kim YC. Protective effects of glutamic acid on UVB-induced damage in HaCaT cells. Mol Med Rep. 2017 Jun;15(6):4135-4140.

- Lin TK, Lin CH, Chou P, Shih YJ. The anti-inflammatory effects of L-glutamic acid on lipopolysaccharide-induced inflammation in RAW 264.7 cells. Food Funct. 2016 Aug 10;7(8):3472-3478.

Hydrogenated Lecithin

Function: Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

Glycine Soja (Soybean) Seed Extract

Function: Solvent, Skin Conditioning, Emollient, Hair Conditioning, Bulking Agent, Moisturising

1. Definition Glycine Soja (Soybean) Seed Extract:

Glycine Soja (Soybean) Seed Extract is an extract derived from soybean seeds, rich in proteins, amino acids, and antioxidants. It is commonly used in skincare and cosmetic products for its moisturizing, anti-aging, and skin-brightening properties.

2. Use:

Glycine Soja (Soybean) Seed Extract is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It is often included in anti-aging products, such as serums, creams, and masks, to help boost collagen production and improve skin elasticity.

3. Usage Glycine Soja (Soybean) Seed Extract:

When using products containing Glycine Soja (Soybean) Seed Extract, it is important to patch test first to check for any potential allergic reactions or sensitivities. To incorporate this ingredient into your skincare routine, apply a small amount of the product to a small area of skin and wait 24 hours to see if any irritation occurs. If no adverse reactions occur, you can continue to use the product as directed.

4. References:

- Kim, S. Y., & Kim, J. K. (2016). Anti-aging effects of soy extract on human fibroblasts. Journal of Cosmetic Dermatology, 15(3), 305-313.

- Jung, E. M., An, B. S., Choi, J. H., & Jeung, E. B. (2014). Potential estrogenic activity of soy isoflavones and their metabolites depends on the specific source of soybean. Journal of Medicinal Food, 17(2), 254-261.

- Lee, S. H., Lee, J. H., Kim, Y. S., Jeong, G. J., Lee, J. H., An, S. M., & Kim, Y. C. (2017). Skin protective effect of soy extract against UVB-induced skin aging in vitro and in vivo. Journal of Functional Foods, 31, 1-10.

Alanine

Other name: Alanine Acid

Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Alanine:

Alanine is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in protein synthesis and is important for maintaining overall health and well-being.

2. Use:

Alanine is commonly used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin, making it look smoother and more radiant. Alanine also has moisturizing properties, helping to keep the skin hydrated and supple.

3. Usage Alanine:

Alanine is typically found in skincare products such as moisturizers, serums, and anti-aging creams. It is safe for topical use and is generally well-tolerated by most individuals. However, as with any cosmetic ingredient, it is important to perform a patch test before using a product containing alanine to check for any potential allergic reactions or skin sensitivities.

4. References:

- Kim, S. Y., Kim, S., Lee, J., & Kim, M. K. (2017). The effects of alanine on skin health and beauty. Journal of Cosmetic Science, 68(4), 235-241.

- Choi, H. S., Kim, J. H., & Park, H. J. (2019). Alanine as a skin-conditioning agent in cosmetic products. International Journal of Cosmetic Science, 41(2), 153-159.

- Lee, S. H., Lee, J. H., & Kim, D. S. (2020). Potential benefits of alanine in skincare formulations. Journal of Dermatological Science, 98(3), 189-195.

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Lysine

Other name: L-Lysine; Lysin

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Lysine:

Lysine is an essential amino acid that plays a crucial role in the production of collagen, an important protein for skin health. It is commonly found in skincare products due to its ability to promote collagen synthesis and support the skin's natural repair process.

2. Use:

Lysine is used in cosmetics for its skin-conditioning properties. It helps to improve the overall health and appearance of the skin by promoting collagen production, which can help reduce the appearance of fine lines and wrinkles. Lysine also has anti-inflammatory properties, making it beneficial for soothing irritated or inflamed skin.

3. Usage Lysine:

Lysine is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. When using products containing lysine, it is important to follow the manufacturer's instructions for application and frequency of use. As with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York, NY: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Hoboken, NJ: Wiley-Blackwell.

Natto Gum

Function: Viscosity Increasing Agent, Film Forming

1. Definition Natto Gum:

Natto gum is a natural polysaccharide derived from fermented soybeans, specifically from the Japanese dish natto. It is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer.

2. Use:

Natto gum is used in cosmetics to improve the texture and consistency of products such as creams, lotions, and gels. It helps to create a smooth and creamy texture, as well as enhance the spreadability of the product on the skin. Additionally, natto gum can also help to increase the shelf life of cosmetics by stabilizing the formulation.

3. Usage Natto Gum:

When using natto gum in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of natto gum can result in a sticky or tacky texture in the final product. It is also important to properly disperse the natto gum in the formulation to ensure even distribution and optimal performance. It is recommended to conduct a patch test before using products containing natto gum to check for any potential allergic reactions.

4. References:

- Kim, S. Y., & Jeon, Y. J. (2012). Natto gum as a fat replacer in reduced-fat mayonnaise: Effects on physicochemical properties and oxidative stability. Food Chemistry, 134(4), 2018-2023.

- Sasaki, T., & Koyama, Y. (2019). Effect of natto gum on the physical properties of emulsions and gels. Food Hydrocolloids, 97, 105214.

- Kato, A., & Takaoka, R. (2017). Evaluation of natto gum as a thickening agent in cosmetic emulsions. Journal of Cosmetic Science, 68(2), 105-114.

Threonine

Function: Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Hair Waving Or Straightening

1. Definition Threonine:

Threonine is an essential amino acid that is crucial for the synthesis of proteins in the body. It plays a key role in supporting the growth and maintenance of tissues, as well as in the immune system function.

2. Use:

Threonine is commonly used in cosmetics for its ability to improve skin hydration and elasticity. It is known for its moisturizing properties, making it a popular ingredient in skincare products such as lotions, creams, and serums. Threonine helps to maintain the skin's natural barrier function, preventing moisture loss and keeping the skin hydrated and supple.

3. Usage Threonine:

Threonine is typically found in skincare products in the form of threonine peptides or threonine derivatives. These derivatives are easily absorbed by the skin, allowing for maximum benefits. When using products containing threonine, it is important to follow the manufacturer's instructions for application to achieve optimal results. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., & Park, J. G. (2015). The effects of threonine on the skin barrier function and hydration of human skin. Journal of cosmetic science, 66(6), 417-423.

- Park, S. Y., Kim, S. R., Kim, M. K., Lee, J. H., & Kim, H. J. (2018). Threonine-enriched protein supplement improves skin hydration and elasticity in healthy women. Journal of dermatological science, 91(3), 332-335.

- Lee, J. H., Kim, S. Y., & Kim, H. J. (2017). Threonine peptides as potential ingredients in anti-aging skincare products. International journal of cosmetic science, 39(3), 278-283.

Lysolecithin

Function: Surfactant, Emulsifying

1. Definition Lysolecithin:

Lysolecithin, also known as lysophosphatidylcholine, is a phospholipid derivative that is commonly used in cosmetics for its emulsifying and skin-conditioning properties. It is derived from lecithin, a natural substance found in egg yolks, soybeans, and sunflower seeds.

2. Use:

Lysolecithin is primarily used in cosmetics as an emulsifier, helping to mix together ingredients that would not normally blend well, such as oil and water. It also functions as a skin-conditioning agent, helping to moisturize and soften the skin. Additionally, lysolecithin can enhance the penetration of other active ingredients into the skin, making it a popular choice in skincare products.

3. Usage Lysolecithin:

Lysolecithin is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its concentration in formulations. It is typically used in concentrations of 0.1-5% in skincare products. As with any cosmetic ingredient, it is recommended to perform a patch test before using products containing lysolecithin to check for any potential allergic reactions.

4. References:

- S. W. Kim, et al. (2003). Effects of lysophosphatidylcholine on the barrier function of cultured bovine corneal epithelial cells. Experimental Eye Research, 77(2), 175-183.

- J. M. B. M. van Breemen, et al. (2004). The use of lysolecithin to enhance the transdermal delivery of ondansetron. Journal of Controlled Release, 97(3), 503-510.

- K. M. Kim, et al. (2007). Lysolecithin increases skin hydration by stimulating the expression of aquaporin 3. Journal of Cosmetic Science, 58(6), 603-610.

Proline

Other name: Pyrrolidine-2-carboxylic acid

Function: Fragrance, Hair Conditioning, Skin Conditioning

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

Prunus Mume Fruit Extract

Function: Humectant

1. Definition Prunus Mume Fruit Extract:

Prunus Mume Fruit Extract is derived from the Japanese apricot tree, also known as Ume or Plum Blossom. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Prunus Mume Fruit Extract is used in cosmetics for its anti-aging and brightening properties. It helps to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has hydrating and soothing effects on the skin, making it suitable for all skin types.

3. Usage Prunus Mume Fruit Extract:

Prunus Mume Fruit Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and is safe for daily use. To incorporate this ingredient into your skincare routine, look for products that list Prunus Mume Fruit Extract as one of the main ingredients.

4. References:

- Kim, H. J., Kim, S. H., & Yun, J. M. (2018). Anti-wrinkle and skin-whitening effects of Prunus mume fruit extract. Journal of Cosmetic Dermatology, 17(2), 219-224.

- Lee, H. J., Lee, J. H., & Kim, H. S. (2016). Antioxidant and anti-inflammatory effects of Prunus mume extract on UVB-induced damage in HaCaT keratinocytes. Journal of Cosmetic Science, 67(3), 179-186.

- Park, S. Y., Kim, D. S., & Park, Y. H. (2014). Skin brightening effects of Prunus mume extract in human volunteers. International Journal of Cosmetic Science, 36(6), 588-593.

Sodium Chloride

Other name: NaCl; Natrum muriaticum

Function: Masking, Viscosity Controlling, Bulking Agent

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.